Result of FASTA (omim) for
pF1KE2304
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2304, 300 aa
1>>>pF1KE2304 300 - 300 aa - 300 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.6397+/-0.000378; mu= -0.8089+/- 0.024
mean_var=155.0111+/-31.200, 0's: 0 Z-trim(117.6): 65 B-trim: 332 in 2/50
Lambda= 0.103013
statistics sampled from 29609 (29675) to 29609 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.692), E-opt: 0.2 (0.348), width: 16
Scan time: 6.740
The best scores are: opt bits E(85289)
NP_000573 (OMIM: 166490) osteopontin isoform OPN-b ( 300) 2024 312.4 6.9e-85
NP_001035147 (OMIM: 166490) osteopontin isoform OP ( 314) 1639 255.2 1.2e-67
NP_001238759 (OMIM: 166490) osteopontin isoform 5 ( 327) 1639 255.2 1.3e-67
XP_016864053 (OMIM: 166490) PREDICTED: osteopontin ( 327) 1639 255.2 1.3e-67
NP_001035149 (OMIM: 166490) osteopontin isoform OP ( 287) 1637 254.9 1.4e-67
NP_001238758 (OMIM: 166490) osteopontin isoform 4 ( 273) 1632 254.1 2.2e-67
>>NP_000573 (OMIM: 166490) osteopontin isoform OPN-b pre (300 aa)
initn: 2024 init1: 2024 opt: 2024 Z-score: 1645.0 bits: 312.4 E(85289): 6.9e-85
Smith-Waterman score: 2024; 100.0% identity (100.0% similar) in 300 aa overlap (1-300:1-300)
10 20 30 40 50 60
pF1KE2 MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSHME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSHME
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 SEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDES
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 NEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKFRISHELDSASSEVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKFRISHELDSASSEVN
250 260 270 280 290 300
>>NP_001035147 (OMIM: 166490) osteopontin isoform OPN-a (314 aa)
initn: 1627 init1: 1627 opt: 1639 Z-score: 1335.4 bits: 255.2 E(85289): 1.2e-67
Smith-Waterman score: 1986; 95.5% identity (95.5% similar) in 314 aa overlap (1-300:1-314)
10 20 30 40 50
pF1KE2 MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQ--
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQNA
10 20 30 40 50 60
60 70 80 90 100
pF1KE2 ------------TLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQS
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQS
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE2 DESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQ
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE2 YPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSH
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE2 KQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKF
250 260 270 280 290 300
290 300
pF1KE2 RISHELDSASSEVN
::::::::::::::
NP_001 RISHELDSASSEVN
310
>>NP_001238759 (OMIM: 166490) osteopontin isoform 5 [Hom (327 aa)
initn: 1627 init1: 1627 opt: 1639 Z-score: 1335.1 bits: 255.2 E(85289): 1.3e-67
Smith-Waterman score: 1788; 92.5% identity (93.2% similar) in 294 aa overlap (21-300:34-327)
10 20 30 40 50
pF1KE2 MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQ
: : . :.:::::::::::::::::::
NP_001 VPRSLDKKAHRVQFQLNRIKAKIELPWGSLQLDCLMKTLKELYNKYPDAVATWLNPDPSQ
10 20 30 40 50 60
60 70 80 90
pF1KE2 KQNLLAPQ--------------TLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDD
:::::::: ::::::::::::::::::::::::::::::::::::::
NP_001 KQNLLAPQNAVSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDD
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE2 VDDTDDSHQSDESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDDTDDSHQSDESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSK
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE2 SKKFRRPDIQYPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKKFRRPDIQYPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQL
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE2 DDQSAETHSHKQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDQSAETHSHKQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPK
250 260 270 280 290 300
280 290 300
pF1KE2 SKEEDKHLKFRISHELDSASSEVN
::::::::::::::::::::::::
NP_001 SKEEDKHLKFRISHELDSASSEVN
310 320
>>XP_016864053 (OMIM: 166490) PREDICTED: osteopontin iso (327 aa)
initn: 1627 init1: 1627 opt: 1639 Z-score: 1335.1 bits: 255.2 E(85289): 1.3e-67
Smith-Waterman score: 1788; 92.5% identity (93.2% similar) in 294 aa overlap (21-300:34-327)
10 20 30 40 50
pF1KE2 MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQ
: : . :.:::::::::::::::::::
XP_016 VPRSLDKKAHRVQFQLNRIKAKIELPWGSLQLDCLMKTLKELYNKYPDAVATWLNPDPSQ
10 20 30 40 50 60
60 70 80 90
pF1KE2 KQNLLAPQ--------------TLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDD
:::::::: ::::::::::::::::::::::::::::::::::::::
XP_016 KQNLLAPQNAVSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDD
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE2 VDDTDDSHQSDESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDDTDDSHQSDESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSK
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE2 SKKFRRPDIQYPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKKFRRPDIQYPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQL
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE2 DDQSAETHSHKQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDQSAETHSHKQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPK
250 260 270 280 290 300
280 290 300
pF1KE2 SKEEDKHLKFRISHELDSASSEVN
::::::::::::::::::::::::
XP_016 SKEEDKHLKFRISHELDSASSEVN
310 320
>>NP_001035149 (OMIM: 166490) osteopontin isoform OPN-c (287 aa)
initn: 1821 init1: 1627 opt: 1637 Z-score: 1334.4 bits: 254.9 E(85289): 1.4e-67
Smith-Waterman score: 1811; 92.3% identity (94.3% similar) in 300 aa overlap (1-300:1-287)
10 20 30 40 50 60
pF1KE2 MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQTL
::::::::::::::::::::::::::::::: .::. :.. : . .::
NP_001 MRIAVICFCLLGITCAIPVKQADSGSSEEKQ------NAVS-------SEETNDFKQETL
10 20 30 40
70 80 90 100 110 120
pF1KE2 PSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVT
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE2 DFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSHME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSHME
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE2 SEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDES
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE2 NEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKFRISHELDSASSEVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKFRISHELDSASSEVN
230 240 250 260 270 280
>>NP_001238758 (OMIM: 166490) osteopontin isoform 4 prec (273 aa)
initn: 1632 init1: 1632 opt: 1632 Z-score: 1330.8 bits: 254.1 E(85289): 2.2e-67
Smith-Waterman score: 1769; 91.0% identity (91.0% similar) in 300 aa overlap (1-300:1-273)
10 20 30 40 50 60
pF1KE2 MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQTL
::::::::::::::::::::::::::::::: ::
NP_001 MRIAVICFCLLGITCAIPVKQADSGSSEEKQ---------------------------TL
10 20 30
70 80 90 100 110 120
pF1KE2 PSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVT
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE2 DFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSHME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSHME
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE2 SEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDES
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE2 NEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKFRISHELDSASSEVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKFRISHELDSASSEVN
220 230 240 250 260 270
300 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 23:15:17 2016 done: Sun Nov 6 23:15:18 2016
Total Scan time: 6.740 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]