FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE2256, 419 aa
  1>>>pF1KE2256     419 - 419 aa - 419 aa
Library: human.CCDS.faa
  18921897 residues in 33420 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.6547+/-0.00107; mu= -1.8739+/- 0.066
 mean_var=513.2237+/-110.442, 0's: 0 Z-trim(117.3): 96  B-trim: 2944 in 3/51
 Lambda= 0.056614
 statistics sampled from 18160 (18273) to 18160 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.804), E-opt: 0.2 (0.547), width:  16
 Scan time:  1.850

The best scores are:                                      opt bits E(33420)
CCDS7710.1 DRD4 gene_id:1815|Hs109|chr11           ( 419) 2932 253.5 2.9e-67
CCDS8362.1 DRD2 gene_id:1813|Hs109|chr11           ( 414)  860 84.3 2.5e-16
CCDS34168.1 HTR1A gene_id:3350|Hs109|chr5          ( 422)  709 71.9 1.3e-12


>>CCDS7710.1 DRD4 gene_id:1815|Hs109|chr11                (419 aa)
 initn: 2932 init1: 2932 opt: 2932  Z-score: 1321.4  bits: 253.5 E(33420): 2.9e-67
Smith-Waterman score: 2932; 100.0% identity (100.0% similar) in 419 aa overlap (1-419:1-419)

               10        20        30        40        50        60
pF1KE2 MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
              310       320       330       340       350       360

              370       380       390       400       410         
pF1KE2 PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
              370       380       390       400       410         

>>CCDS8362.1 DRD2 gene_id:1813|Hs109|chr11                (414 aa)
 initn: 618 init1: 222 opt: 860  Z-score: 406.8  bits: 84.3 E(33420): 2.5e-16
Smith-Waterman score: 868; 40.8% identity (62.3% similar) in 390 aa overlap (43-418:43-414)

             20        30        40        50        60        70  
pF1KE2 LAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSF
                                     :::.... :: :::..:. :.:::: :: .
CCDS83 LERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYL
             20        30        40        50        60        70  

             80        90       100       110       120       130  
pF1KE2 IVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVD
       :::::.::::.: ::.:  :: :: :  : .:   :: ....:::.:::::.::::::.:
CCDS83 IVSLAVADLLVATLVMPWVVYLEVVG-EWKFSRIHCDIFVTLDVMMCTASILNLCAISID
             80        90        100       110       120       130 

            140        150       160       170       180       190 
pF1KE2 RFVAVAVPLRYN-RQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRD
       :..:::.:. :: : ...::  ..:. .:.:: ... :.: :::..   :   : . .  
CCDS83 RYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNA---DQNECIIANPA
             140       150       160       170          180        

             200       210       220       230       240       250 
pF1KE2 YVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAP
       .:::::. ::..:  . ::.:   .  :.:    :: ... .   :       .:   : 
CCDS83 FVVYSSIVSFYVPFIVTLLVYIKIYIVLRR----RRKRVNTKRSSRAFRAHLRAPLKEAA
      190       200       210           220       230       240    

             260       270       280           290         300     
pF1KE2 RLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQ----DPC--GPDCAPPAPGLPPDP
       :  :.      .  .:     :     .:  ::  :    ::   :   .: .:.  :. 
CCDS83 RRAQELEMEMLSSTSP-----PERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPA-KPEK
          250       260            270       280       290         

         310       320       330       340              350        
pF1KE2 CGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGR-------ERKAMRVLPVVVGAFLLC
        :     :    :  .  :: :. . :   :  .:       :.:: ..: .:.:.:..:
CCDS83 NGHAKDHPKI--AKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIIC
      300         310       320       330       340       350      

      360       370       380       390       400       410        
pF1KE2 WTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRAC
       : :::..:: .  :  :..:: : :: :::::::::.::.:::.:: :::..: : :. :
CCDS83 WLPFFITHILNIHCD-CNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILH-C
        360       370        380       390       400       410     

        
pF1KE2 C

>>CCDS34168.1 HTR1A gene_id:3350|Hs109|chr5               (422 aa)
 initn: 657 init1: 195 opt: 709  Z-score: 340.1  bits: 71.9 E(33420): 1.3e-12
Smith-Waterman score: 709; 32.5% identity (61.2% similar) in 418 aa overlap (18-418:16-417)

               10        20        30             40        50     
pF1KE2 MGNRSTADADGLLAGRGPAAGASAGASAGLAG-----QGAAALVGGVLLIGAVLAGNSLV
                        ::   ..: ..:..      :  ..:. :.:.. ::: ::. :
CCDS34   MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVL-GNACV
                 10        20        30        40        50        

          60        70        80        90       100       110     
pF1KE2 CVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMD
        ...: ::.::. .: .: :::..::....::::. .  .: .  : :.   :: ..:.:
CCDS34 VAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLN-KWTLGQVTCDLFIALD
        60        70        80        90       100        110      

         120       130       140       150       160       170     
pF1KE2 VMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLN
       :. ::.::..::::..::. :.. :. :  .   ::   ::. :::..  .. : . :  
CCDS34 VLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWR
        120       130       140       150       160       170      

         180         190       200       210       220       230   
pF1KE2 DVRGR-DPAVCRL-EDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGR
         . : :: .: . .:. :..::.  .:..:  :::.::   ::.  :... . .:    
CCDS34 TPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRA-ARFRIRKTVK----
        180       190       200       210       220        230     

           240       250       260        270       280       290  
pF1KE2 APRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAP-GLPRGPCGPDCAPAAPSLPQDPCGP
          . .:      . :::.  ..  : . .     :.     :  :: .:    .:  . 
CCDS34 -KVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAAL
              240       250       260       270       280       290

                  300         310       320       330       340    
pF1KE2 DCAP------PAPGLP-PDPCG-SNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKA
       .             :: :.  : . :::      :..  ..  ... .:.  .. ::::.
CCDS34 EVIEVHRVGNSKEHLPLPSEAGPTPCAP------ASFERKNERNAEAKRKMALA-RERKT
              300       310             320       330        340   

          350       360       370        380       390       400   
pF1KE2 MRVLPVVVGAFLLCWTPFFVVHITQALCPA-CSVPPRLVSAVTWLGYVNSALNPVIYTVF
       ...: ...:.:.::: :::.: ..  .: . : .:  : . ..:::: :: ::::::. :
CCDS34 VKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYF
           350       360       370       380       390       400   

           410             
pF1KE2 NAEFRNVFRKALRACC    
       : .:.:.:.: .. :     
CCDS34 NKDFQNAFKKIIK-CKFCRQ
           410        420  




419 residues in 1 query   sequences
18921897 residues in 33420 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Jul 20 18:04:05 2018 done: Fri Jul 20 18:04:05 2018
 Total Scan time:  1.850 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]