Result of FASTA (ccds) for
pF1KE1947
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1947, 501 aa
1>>>pF1KE1947 501 - 501 aa - 501 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3548+/-0.000907; mu= 18.0048+/- 0.055
mean_var=71.6474+/-14.563, 0's: 0 Z-trim(106.4): 23 B-trim: 243 in 1/48
Lambda= 0.151521
statistics sampled from 8913 (8936) to 8913 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.652), E-opt: 0.2 (0.274), width: 16
Scan time: 1.360
The best scores are: opt bits E(32554)
CCDS8383.1 BACE1 gene_id:23621|Hs108|chr11 ( 501) 3417 756.4 1.7e-218
CCDS55787.1 BACE1 gene_id:23621|Hs108|chr11 ( 401) 2607 579.3 2.8e-165
CCDS44740.1 BACE1 gene_id:23621|Hs108|chr11 ( 457) 2144 478.1 9.1e-135
CCDS55786.1 BACE1 gene_id:23621|Hs108|chr11 ( 376) 1960 437.8 9.9e-123
CCDS44739.1 BACE1 gene_id:23621|Hs108|chr11 ( 476) 1960 437.9 1.2e-122
CCDS44741.1 BACE1 gene_id:23621|Hs108|chr11 ( 432) 1959 437.6 1.3e-122
CCDS13668.1 BACE2 gene_id:25825|Hs108|chr21 ( 518) 1535 345.0 1.2e-94
CCDS13670.1 BACE2 gene_id:25825|Hs108|chr21 ( 396) 1249 282.4 6.3e-76
CCDS13669.1 BACE2 gene_id:25825|Hs108|chr21 ( 468) 1041 237.0 3.5e-62
CCDS73013.1 CTSE gene_id:1510|Hs108|chr1 ( 396) 321 79.5 7.4e-15
CCDS73012.1 CTSE gene_id:1510|Hs108|chr1 ( 363) 308 76.7 4.9e-14
CCDS7725.1 CTSD gene_id:1509|Hs108|chr11 ( 412) 267 67.7 2.7e-11
>>CCDS8383.1 BACE1 gene_id:23621|Hs108|chr11 (501 aa)
initn: 3417 init1: 3417 opt: 3417 Z-score: 4036.4 bits: 756.4 E(32554): 1.7e-218
Smith-Waterman score: 3417; 100.0% identity (100.0% similar) in 501 aa overlap (1-501:1-501)
10 20 30 40 50 60
pF1KE1 MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 HVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 HVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
430 440 450 460 470 480
490 500
pF1KE1 RCLRCLRQQHDDFADDISLLK
:::::::::::::::::::::
CCDS83 RCLRCLRQQHDDFADDISLLK
490 500
>>CCDS55787.1 BACE1 gene_id:23621|Hs108|chr11 (401 aa)
initn: 2607 init1: 2607 opt: 2607 Z-score: 3080.8 bits: 579.3 E(32554): 2.8e-165
Smith-Waterman score: 2607; 100.0% identity (100.0% similar) in 384 aa overlap (118-501:18-401)
90 100 110 120 130 140
pF1KE1 LNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVS
::::::::::::::::::::::::::::::
CCDS55 MVPFIYLQAHFTLCSGWSSTYRDLRKGVYVPYTQGKWEGELGTDLVS
10 20 30 40
150 160 170 180 190 200
pF1KE1 IPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 IPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHV
50 60 70 80 90 100
210 220 230 240 250 260
pF1KE1 PNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 PNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRV
110 120 130 140 150 160
270 280 290 300 310 320
pF1KE1 EINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 EINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQ
170 180 190 200 210 220
330 340 350 360 370 380
pF1KE1 LVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQ
230 240 250 260 270 280
390 400 410 420 430 440
pF1KE1 SSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 SSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNI
290 300 310 320 330 340
450 460 470 480 490 500
pF1KE1 PQTDESTLMTIAYVMAAICALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 PQTDESTLMTIAYVMAAICALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLLK
350 360 370 380 390 400
>>CCDS44740.1 BACE1 gene_id:23621|Hs108|chr11 (457 aa)
initn: 3118 init1: 2130 opt: 2144 Z-score: 2533.0 bits: 478.1 E(32554): 9.1e-135
Smith-Waterman score: 3034; 91.2% identity (91.2% similar) in 501 aa overlap (1-501:1-457)
10 20 30 40 50 60
pF1KE1 MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
:::::::::::::::::::::::::
CCDS44 YRDLRKGVYVPYTQGKWEGELGTDL-----------------------------------
130 140
190 200 210 220 230 240
pF1KE1 GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI
:::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ---------PDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI
150 160 170 180 190
250 260 270 280 290 300
pF1KE1 DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
200 210 220 230 240 250
310 320 330 340 350 360
pF1KE1 VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
260 270 280 290 300 310
370 380 390 400 410 420
pF1KE1 ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC
320 330 340 350 360 370
430 440 450 460 470 480
pF1KE1 HVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 HVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
380 390 400 410 420 430
490 500
pF1KE1 RCLRCLRQQHDDFADDISLLK
:::::::::::::::::::::
CCDS44 RCLRCLRQQHDDFADDISLLK
440 450
>>CCDS55786.1 BACE1 gene_id:23621|Hs108|chr11 (376 aa)
initn: 1960 init1: 1960 opt: 1960 Z-score: 2316.9 bits: 437.8 E(32554): 9.9e-123
Smith-Waterman score: 2376; 93.5% identity (93.5% similar) in 384 aa overlap (118-501:18-376)
90 100 110 120 130 140
pF1KE1 LNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVS
::::::::::::::::::::::::::::::
CCDS55 MVPFIYLQAHFTLCSGWSSTYRDLRKGVYVPYTQGKWEGELGTDLVS
10 20 30 40
150 160 170 180 190 200
pF1KE1 IPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHV
::::::::::::::::::::::::::::::::::::::::::
CCDS55 IPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIAR------------------
50 60 70 80
210 220 230 240 250 260
pF1KE1 PNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRV
:::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 -------LCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRV
90 100 110 120 130 140
270 280 290 300 310 320
pF1KE1 EINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 EINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQ
150 160 170 180 190 200
330 340 350 360 370 380
pF1KE1 LVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQ
210 220 230 240 250 260
390 400 410 420 430 440
pF1KE1 SSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 SSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNI
270 280 290 300 310 320
450 460 470 480 490 500
pF1KE1 PQTDESTLMTIAYVMAAICALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 PQTDESTLMTIAYVMAAICALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLLK
330 340 350 360 370
>>CCDS44739.1 BACE1 gene_id:23621|Hs108|chr11 (476 aa)
initn: 1960 init1: 1960 opt: 1960 Z-score: 2315.4 bits: 437.9 E(32554): 1.2e-122
Smith-Waterman score: 3186; 95.0% identity (95.0% similar) in 501 aa overlap (1-501:1-476)
10 20 30 40 50 60
pF1KE1 MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI
::::::::: ::::::::::::::::::::::::::
CCDS44 GLAYAEIAR-------------------------LCGAGFPLNQSEVLASVGGSMIIGGI
190 200 210
250 260 270 280 290 300
pF1KE1 DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE1 VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE1 ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE1 HVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 HVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
400 410 420 430 440 450
490 500
pF1KE1 RCLRCLRQQHDDFADDISLLK
:::::::::::::::::::::
CCDS44 RCLRCLRQQHDDFADDISLLK
460 470
>>CCDS44741.1 BACE1 gene_id:23621|Hs108|chr11 (432 aa)
initn: 1959 init1: 1959 opt: 1959 Z-score: 2314.8 bits: 437.6 E(32554): 1.3e-122
Smith-Waterman score: 2813; 86.2% identity (86.2% similar) in 501 aa overlap (1-501:1-432)
10 20 30 40 50 60
pF1KE1 MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
:::::::::::::::::::::::::
CCDS44 YRDLRKGVYVPYTQGKWEGELGTDL-----------------------------------
130 140
190 200 210 220 230 240
pF1KE1 GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI
::::::::::::::::::::::::::
CCDS44 ----------------------------------LCGAGFPLNQSEVLASVGGSMIIGGI
150 160 170
250 260 270 280 290 300
pF1KE1 DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
180 190 200 210 220 230
310 320 330 340 350 360
pF1KE1 VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
240 250 260 270 280 290
370 380 390 400 410 420
pF1KE1 ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC
300 310 320 330 340 350
430 440 450 460 470 480
pF1KE1 HVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 HVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
360 370 380 390 400 410
490 500
pF1KE1 RCLRCLRQQHDDFADDISLLK
:::::::::::::::::::::
CCDS44 RCLRCLRQQHDDFADDISLLK
420 430
>>CCDS13668.1 BACE2 gene_id:25825|Hs108|chr21 (518 aa)
initn: 1512 init1: 668 opt: 1535 Z-score: 1812.7 bits: 345.0 E(32554): 1.2e-94
Smith-Waterman score: 1535; 49.6% identity (77.0% similar) in 448 aa overlap (54-500:71-512)
30 40 50 60 70 80
pF1KE1 HGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGS
:. ..:. :::::.: ::.:::.:: .:.
CCDS13 RVVAPTPGPGTPAERHADGLALALEPALASPAGAANFLAMVDNLQGDSGRGYYLEMLIGT
50 60 70 80 90 100
90 100 110 120 130 140
pF1KE1 PPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGT
::: :.::::::::::::...:: .. :.. . :::::. : : ::::.: : .:
CCDS13 PPQKLQILVDTGSSNFAVAGTPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGE
110 120 130 140 150 160
150 160 170 180 190 200
pF1KE1 DLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVK
:::.::.: :.. .:::.: ::..::. : .:.:::::::: .:.:..::: ::::::
CCDS13 DLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVT
170 180 190 200 210 220
210 220 230 240 250 260
pF1KE1 QTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVI
:...::.::.:.::::.:. : .. :::...:::. ::: :..:::::..::::..
CCDS13 QANIPNVFSMQMCGAGLPVAGS---GTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIE
230 240 250 260 270
270 280 290 300 310 320
pF1KE1 IVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFW
:...::.::.:..::.::: ::.::::::: ::::.:::.:.:... :: .: ::::
CCDS13 ILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGFW
280 290 300 310 320 330
330 340 350 360 370 380
pF1KE1 LGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKF
: ::.:: . :::. :: ::.:: : ...::::::::: :..:. .. . . ::.:
CCDS13 TGSQLACWTNSETPWSYFPKISIYLRDENSSRSFRITILPQLYIQPMMGAGLNYE-CYRF
340 350 360 370 380 390
390 400 410 420 430 440
pF1KE1 AISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDC
.:: :... :.::..::::::.::::.::.:::.: : .. . ::: : :. .
CCDS13 GISPSTNALVIGATVMEGFYVIFDRAQKRVGFAASPCAEIAGAAVSEISGPFSTEDVASN
400 410 420 430 440 450
450 460 470 480 490 500
pF1KE1 GYNIPQTDESTLMTIAYVMAAIC-ALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLLK
. .: : ..:.. ..: :.... . :.. .:: : : . . ..: : :
CCDS13 CVPAQSLSEPILWIVSYALMSVCGAILLVLIVLLLLPFRCQR--RPRDPEVVNDESSLVR
460 470 480 490 500 510
CCDS13 HRWK
>>CCDS13670.1 BACE2 gene_id:25825|Hs108|chr21 (396 aa)
initn: 1247 init1: 668 opt: 1249 Z-score: 1476.5 bits: 282.4 E(32554): 6.3e-76
Smith-Waterman score: 1249; 56.4% identity (82.1% similar) in 312 aa overlap (54-365:71-379)
30 40 50 60 70 80
pF1KE1 HGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGS
:. ..:. :::::.: ::.:::.:: .:.
CCDS13 RVVAPTPGPGTPAERHADGLALALEPALASPAGAANFLAMVDNLQGDSGRGYYLEMLIGT
50 60 70 80 90 100
90 100 110 120 130 140
pF1KE1 PPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGT
::: :.::::::::::::...:: .. :.. . :::::. : : ::::.: : .:
CCDS13 PPQKLQILVDTGSSNFAVAGTPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGE
110 120 130 140 150 160
150 160 170 180 190 200
pF1KE1 DLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVK
:::.::.: :.. .:::.: ::..::. : .:.:::::::: .:.:..::: ::::::
CCDS13 DLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVT
170 180 190 200 210 220
210 220 230 240 250 260
pF1KE1 QTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVI
:...::.::.:.::::.:. : .. :::...:::. ::: :..:::::..::::..
CCDS13 QANIPNVFSMQMCGAGLPVAGS---GTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIE
230 240 250 260 270
270 280 290 300 310 320
pF1KE1 IVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFW
:...::.::.:..::.::: ::.::::::: ::::.:::.:.:... :: .: ::::
CCDS13 ILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGFW
280 290 300 310 320 330
330 340 350 360 370 380
pF1KE1 LGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKF
: ::.:: . :::. :: ::.:: : ...:::::::::.
CCDS13 TGSQLACWTNSETPWSYFPKISIYLRDENSSRSFRITILPQKLQVLQCLKFPGLSQQRM
340 350 360 370 380 390
390 400 410 420 430 440
pF1KE1 AISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDC
>>CCDS13669.1 BACE2 gene_id:25825|Hs108|chr21 (468 aa)
initn: 1276 init1: 668 opt: 1041 Z-score: 1229.8 bits: 237.0 E(32554): 3.5e-62
Smith-Waterman score: 1209; 43.3% identity (69.2% similar) in 448 aa overlap (54-500:71-462)
30 40 50 60 70 80
pF1KE1 HGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGS
:. ..:. :::::.: ::.:::.:: .:.
CCDS13 RVVAPTPGPGTPAERHADGLALALEPALASPAGAANFLAMVDNLQGDSGRGYYLEMLIGT
50 60 70 80 90 100
90 100 110 120 130 140
pF1KE1 PPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGT
::: :.::::::::::::...:: .. :.. . :::::. : : ::::.: : .:
CCDS13 PPQKLQILVDTGSSNFAVAGTPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGE
110 120 130 140 150 160
150 160 170 180 190 200
pF1KE1 DLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVK
:::.::.: :.. .:::.: ::..::. : .:.:::::::: .:.:..::: ::::::
CCDS13 DLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVT
170 180 190 200 210 220
210 220 230 240 250 260
pF1KE1 QTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVI
:...::.::.:.::::.:. : .. :::...:::. ::: :..:::::..::::..
CCDS13 QANIPNVFSMQMCGAGLPVAGS---GTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIE
230 240 250 260 270
270 280 290 300 310 320
pF1KE1 IVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFW
:...::.::.:..::.::: ::.::::::: ::::.:::.:.:... ::
CCDS13 ILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARAS----------
280 290 300 310 320
330 340 350 360 370 380
pF1KE1 LGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKF
:. :..:. .. . . ::.:
CCDS13 ------------------------LL----------------YIQPMMGAGLNYE-CYRF
330 340
390 400 410 420 430 440
pF1KE1 AISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDC
.:: :... :.::..::::::.::::.::.:::.: : .. . ::: : :. .
CCDS13 GISPSTNALVIGATVMEGFYVIFDRAQKRVGFAASPCAEIAGAAVSEISGPFSTEDVASN
350 360 370 380 390 400
450 460 470 480 490 500
pF1KE1 GYNIPQTDESTLMTIAYVMAAIC-ALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLLK
. .: : ..:.. ..: :.... . :.. .:: : : . . ..: : :
CCDS13 CVPAQSLSEPILWIVSYALMSVCGAILLVLIVLLLLPFRCQR--RPRDPEVVNDESSLVR
410 420 430 440 450 460
CCDS13 HRWK
>>CCDS73013.1 CTSE gene_id:1510|Hs108|chr1 (396 aa)
initn: 284 init1: 95 opt: 321 Z-score: 380.2 bits: 79.5 E(32554): 7.4e-15
Smith-Waterman score: 390; 27.5% identity (57.0% similar) in 349 aa overlap (75-416:78-392)
50 60 70 80 90 100
pF1KE1 RETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGA-
:. ...:::::..... ::::::. : .
CCDS73 SHNLDMIQFTESCSMDQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSV
50 60 70 80 90 100
110 120 130 140 150 160
pF1KE1 ---APHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANI
.: : .: . :::: . .. . : :. : .:.: ::. .: .:. .
CCDS73 YCTSPACKTHSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSV-EGLTVVGQQFG
110 120 130 140 150 160
170 180 190 200 210 220
pF1KE1 AAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGF
..:: . :.. ....:::::.: .: .. : ::... : :: .: . .. .
CCDS73 ESVTEPGQTFVD-AEFDGILGLGYPSLAV--GGVTPVFDNMMAQ----NLVDLPMFSVYM
170 180 190 200 210
230 240 250 260 270 280
pF1KE1 PLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKE
: ...:. .:.:: ::: ..::: ..:. .. :... . ....: : :.:
CCDS73 SSNPE---GGAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGG--TVMFCSE
220 230 240 250 260 270
290 300 310 320 330 340
pF1KE1 YNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNI
..:::.::. . :. .. ..: :: :: . : : . :.
CCDS73 GC--QAIVDTGTSLITGPSDKIKQLQNAIGAAPV-----DGEYAVE---C-----ANLNV
280 290 300 310
350 360 370 380 390
pF1KE1 FPVISLYLMGEVTNQSFRITILPQQY--LRPVEDVATSQDDCYKFAISQSSTGT-VMGAV
.: ... . : :. : : : :. . .. . : . ..: :
CCDS73 MPDVTFTING------VPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPLWILGDV
320 330 340 350 360 370
400 410 420 430 440 450
pF1KE1 IMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMT
... :: ::::. .:.:.:
CCDS73 FIRQFYSVFDRGNNRVGLAPAVP
380 390
501 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Apr 22 20:29:05 2018 done: Sun Apr 22 20:29:06 2018
Total Scan time: 1.360 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]