FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1860, 380 aa
  1>>>pF1KE1860 380 - 380 aa - 380 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 13.7955+/-0.00114; mu= -16.1346+/- 0.069
 mean_var=708.8464+/-145.517, 0's: 0 Z-trim(118.8): 24  B-trim: 203 in 1/52
 Lambda= 0.048172
 statistics sampled from 19796 (19819) to 19796 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.841), E-opt: 0.2 (0.609), width:  16
 Scan time:  3.550

The best scores are:                                      opt bits E(32554)
CCDS33051.1 VASP gene_id:7408|Hs108|chr19          ( 380) 2636 197.3 1.9e-50
CCDS81851.1 EVL gene_id:51466|Hs108|chr14          ( 416)  958 80.7 2.6e-15
CCDS9955.1 EVL gene_id:51466|Hs108|chr14           ( 418)  951 80.3 3.6e-15


>>CCDS33051.1 VASP gene_id:7408|Hs108|chr19               (380 aa)
 initn: 2636 init1: 2636 opt: 2636  Z-score: 1019.2  bits: 197.3 E(32554): 1.9e-50
Smith-Waterman score: 2636; 100.0% identity (100.0% similar) in 380 aa overlap (1-380:1-380)

               10        20        30        40        50        60
pF1KE1 MSETVICSSRATVMLYDDGNKRWLPAGTGPQAFSRVQIYHNPTANSFRVVGRKMQPDQQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 MSETVICSSRATVMLYDDGNKRWLPAGTGPQAFSRVQIYHNPTANSFRVVGRKMQPDQQV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 VINCAIVRGVKYNQATPNFHQWRDARQVWGLNFGSKEDAAQFAAGMASALEALEGGGPPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 VINCAIVRGVKYNQATPNFHQWRDARQVWGLNFGSKEDAAQFAAGMASALEALEGGGPPP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 PPALPTWSVPNGPSPEEVEQQKRQQPGPSEHIERRVSNAGGPPAPPAGGPPPPPGPPPPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 PPALPTWSVPNGPSPEEVEQQKRQQPGPSEHIERRVSNAGGPPAPPAGGPPPPPGPPPPP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 GPPPPPGLPPSGVPAAAHGAGGGPPPAPPLPAAQGPGGGGAGAPGLAAAIAGAKLRKVSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 GPPPPPGLPPSGVPAAAHGAGGGPPPAPPLPAAQGPGGGGAGAPGLAAAIAGAKLRKVSK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 QEEASGGPTAPKAESGRSGGGGLMEEMNAMLARRRKATQVGEKTPKDESANQEEPEARVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 QEEASGGPTAPKAESGRSGGGGLMEEMNAMLARRRKATQVGEKTPKDESANQEEPEARVP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE1 AQSESVRRPWEKNSTTLPRMKSSSSVTTSETQPCTPSSSDYSDLQRVKQELLEEVKKELQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 AQSESVRRPWEKNSTTLPRMKSSSSVTTSETQPCTPSSSDYSDLQRVKQELLEEVKKELQ
              310       320       330       340       350       360

              370       380
pF1KE1 KVKEEIIEAFVQELRKRGSP
       ::::::::::::::::::::
CCDS33 KVKEEIIEAFVQELRKRGSP
              370       380

>>CCDS81851.1 EVL gene_id:51466|Hs108|chr14               (416 aa)
 initn: 338 init1: 338 opt: 958  Z-score: 388.5  bits: 80.7 E(32554): 2.6e-15
Smith-Waterman score: 1100; 48.1% identity (67.5% similar) in 428 aa overlap (1-374:1-410)

               10        20        30        40        50        60
pF1KE1 MSETVICSSRATVMLYDDGNKRWLPAGTGPQAFSRVQIYHNPTANSFRVVGRKMQPDQQV
       :::  ::..::.::.::: .:.:.:   : :.:::..:::: ..:.::::: :.: ::::
CCDS81 MSEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASNTFRVVGVKLQ-DQQV
               10        20        30        40        50          

               70        80        90       100       110          
pF1KE1 VINCAIVRGVKYNQATPNFHQWRDARQVWGLNFGSKEDAAQFAAGMASALEALEG--GGP
       ::: .::.:.:::::::.::::::::::.::::.:::.:. :. .:  ::. ...  :::
CCDS81 VINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMNSQEGGP
      60        70        80        90       100       110         

      120       130       140            150       160         170 
pF1KE1 PPPPALPTWSVPNGPSPEEVEQQKRQ-----QPGPSEHIERRVSNAGG--PPAPPAGGPP
                .: :::::.:.. :.::     :   .: .:::.: .:   ::. :...  
CCDS81 SSQR-----QVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGHPSSAAS
     120            130       140       150       160       170    

                180       190       200       210         220      
pF1KE1 PP---PGPPPPPGPPPPPGLPPSGVPAAAHGAGGGPPPAPPLPA--AQGPGGGGAGAPGL
        :    :::::: :: ::  ::.:.          ::: :::::  ::: .   ..  ::
CCDS81 APVSCSGPPPPPPPPVPP--PPTGAT---------PPPPPPLPAGGAQGSSHDESSMSGL
          180       190                  200       210       220   

        230       240               250       260       270        
pF1KE1 AAAIAGAKLRKVSKQEEASGG--PT------APKAESGRSGGGGLMEEMNAMLARRRKA-
       ::::::::::.:.. :.::::  :.      : .: :: .:::::::::: .::.:::: 
CCDS81 AAAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSG-GGGGGLMEEMNKLLAKRRKAA
           230       240       250       260        270       280  

       280       290                  300       310           320  
pF1KE1 TQVGEKTPKDESANQEE-------PEARV----PAQSESVRRPWEK-NSTTLPR---MKS
       .:  . . : :. .: :       : .:.    : .::. :.:::. ::.  :    .. 
CCDS81 SQSDKPAEKKEDESQMEDPSTSPSPGTRAASQPPNSSEAGRKPWERSNSVEKPVSSILSR
            290       300       310       320       330       340  

                   330                340       350       360      
pF1KE1 SSSVTTS-------ETQPCT---PSSS------DYSDLQRVKQELLEEVKKELQKVKEEI
       . ::. :       ..:: .   :..:      :  ::.:.:::.:::: .::.::::::
CCDS81 TPSVAKSPEAKSPLQSQPHSRMKPAGSVNDMALDAFDLDRMKQEILEEVVRELHKVKEEI
            350       360       370       380       390       400  

        370       380
pF1KE1 IEAFVQELRKRGSP
       :.:. :::      
CCDS81 IDAIRQELSGISTT
            410      

>>CCDS9955.1 EVL gene_id:51466|Hs108|chr14                (418 aa)
 initn: 338 init1: 338 opt: 951  Z-score: 385.9  bits: 80.3 E(32554): 3.6e-15
Smith-Waterman score: 1093; 48.0% identity (67.4% similar) in 427 aa overlap (2-374:4-412)

                 10        20        30        40        50        
pF1KE1   MSETVICSSRATVMLYDDGNKRWLPAGTGPQAFSRVQIYHNPTANSFRVVGRKMQPDQ
          ::  ::..::.::.::: .:.:.:   : :.:::..:::: ..:.::::: :.: ::
CCDS99 MATSEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASNTFRVVGVKLQ-DQ
               10        20        30        40        50          

       60        70        80        90       100       110        
pF1KE1 QVVINCAIVRGVKYNQATPNFHQWRDARQVWGLNFGSKEDAAQFAAGMASALEALEG--G
       ::::: .::.:.:::::::.::::::::::.::::.:::.:. :. .:  ::. ...  :
CCDS99 QVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMNSQEG
      60        70        80        90       100       110         

        120       130       140            150       160           
pF1KE1 GPPPPPALPTWSVPNGPSPEEVEQQKRQ-----QPGPSEHIERRVSNAGG--PPAPPAGG
       ::         .: :::::.:.. :.::     :   .: .:::.: .:   ::. :...
CCDS99 GPSSQR-----QVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGHPSSA
     120            130       140       150       160       170    

     170          180       190       200       210         220    
pF1KE1 PPPP---PGPPPPPGPPPPPGLPPSGVPAAAHGAGGGPPPAPPLPA--AQGPGGGGAGAP
          :    :::::: :: ::  ::.:.          ::: :::::  ::: .   ..  
CCDS99 ASAPVSCSGPPPPPPPPVPP--PPTGAT---------PPPPPPLPAGGAQGSSHDESSMS
          180       190         200                210       220   

          230       240               250       260       270      
pF1KE1 GLAAAIAGAKLRKVSKQEEASGG--PT------APKAESGRSGGGGLMEEMNAMLARRRK
       ::::::::::::.:.. :.::::  :.      : .: :: .:::::::::: .::.:::
CCDS99 GLAAAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSG-GGGGGLMEEMNKLLAKRRK
           230       240       250       260        270       280  

         280       290                  300       310           320
pF1KE1 A-TQVGEKTPKDESANQEE-------PEARV----PAQSESVRRPWEK-NSTTLPR---M
       : .:  . . : :. .: :       : .:.    : .::. :.:::. ::.  :    .
CCDS99 AASQSDKPAEKKEDESQMEDPSTSPSPGTRAASQPPNSSEAGRKPWERSNSVEKPVSSIL
            290       300       310       320       330       340  

                     330                340       350       360    
pF1KE1 KSSSSVTTS-------ETQPCT---PSSS------DYSDLQRVKQELLEEVKKELQKVKE
       . . ::. :       ..:: .   :..:      :  ::.:.:::.:::: .::.::::
CCDS99 SRTPSVAKSPEAKSPLQSQPHSRMKPAGSVNDMALDAFDLDRMKQEILEEVVRELHKVKE
            350       360       370       380       390       400  

          370       380
pF1KE1 EIIEAFVQELRKRGSP
       :::.:. :::      
CCDS99 EIIDAIRQELSGISTT
            410        




380 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 12:09:57 2016 done: Sun Nov  6 12:09:57 2016
 Total Scan time:  3.550 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]