Result of FASTA (ccds) for
pF1KE1761
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1761, 268 aa
1>>>pF1KE1761 268 - 268 aa - 268 aa
Library: human.CCDS.faa
18921897 residues in 33420 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.4100+/-0.00116; mu= 7.6558+/- 0.071
mean_var=281.2857+/-56.025, 0's: 0 Z-trim(112.5): 112 B-trim: 0 in 0/51
Lambda= 0.076472
statistics sampled from 13324 (13434) to 13324 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.727), E-opt: 0.2 (0.402), width: 16
Scan time: 1.150
The best scores are: opt bits E(33420)
CCDS12489.1 CAPNS1 gene_id:826|Hs109|chr19 ( 268) 1826 214.3 7.3e-56
CCDS54010.1 CAPNS2 gene_id:84290|Hs109|chr16 ( 248) 1117 136.0 2.5e-32
CCDS45246.1 CAPN3 gene_id:825|Hs109|chr15 ( 309) 753 96.0 3.4e-20
CCDS32207.1 CAPN3 gene_id:825|Hs109|chr15 ( 815) 753 96.6 5.9e-20
CCDS45245.1 CAPN3 gene_id:825|Hs109|chr15 ( 821) 753 96.6 6e-20
CCDS10085.1 CAPN3 gene_id:825|Hs109|chr15 ( 729) 749 96.1 7.6e-20
CCDS10086.1 CAPN3 gene_id:825|Hs109|chr15 ( 156) 655 84.8 4.2e-17
CCDS44644.1 CAPN1 gene_id:823|Hs109|chr11 ( 714) 634 83.4 4.9e-16
CCDS53478.1 CAPN2 gene_id:824|Hs109|chr1 ( 622) 606 80.2 3.9e-15
CCDS31035.1 CAPN2 gene_id:824|Hs109|chr1 ( 700) 606 80.3 4.1e-15
CCDS81431.1 CAPN9 gene_id:10753|Hs109|chr1 ( 627) 557 74.8 1.7e-13
CCDS31053.1 CAPN9 gene_id:10753|Hs109|chr1 ( 664) 557 74.9 1.7e-13
CCDS1586.1 CAPN9 gene_id:10753|Hs109|chr1 ( 690) 557 74.9 1.7e-13
CCDS47436.1 CAPN11 gene_id:11131|Hs109|chr6 ( 739) 525 71.4 2.1e-12
CCDS73038.1 CAPN8 gene_id:388743|Hs109|chr1 ( 703) 505 69.2 9.4e-12
>>CCDS12489.1 CAPNS1 gene_id:826|Hs109|chr19 (268 aa)
initn: 1826 init1: 1826 opt: 1826 Z-score: 1116.6 bits: 214.3 E(33420): 7.3e-56
Smith-Waterman score: 1826; 100.0% identity (100.0% similar) in 268 aa overlap (1-268:1-268)
10 20 30 40 50 60
pF1KE1 MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 ILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 MNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 MNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 FDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 FDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMF
190 200 210 220 230 240
250 260
pF1KE1 RAFKSLDKDGTGQIQVNIQEWLQLTMYS
::::::::::::::::::::::::::::
CCDS12 RAFKSLDKDGTGQIQVNIQEWLQLTMYS
250 260
>>CCDS54010.1 CAPNS2 gene_id:84290|Hs109|chr16 (248 aa)
initn: 1068 init1: 1068 opt: 1117 Z-score: 694.2 bits: 136.0 E(33420): 2.5e-32
Smith-Waterman score: 1122; 67.2% identity (86.4% similar) in 250 aa overlap (20-268:10-248)
10 20 30 40 50 60
pF1KE1 MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMR
: :::..::::. :::: ::: . ::
CCDS54 MFLAKALLEGADRGLGEALGGLF-------GGGGQRREGGGRNIGG----
10 20 30
70 80 90 100 110
pF1KE1 ILGGVISAISEAAA-QYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATE
:.::... :::::: ::.::::: . :....::.::::::.::. :.:::: ::::.::.
CCDS54 IVGGIVNFISEAAAAQYTPEPPPTQQHFTSVEASESEEVRRFRQQFTQLAGPDMEVGATD
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE1 LMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYK
::::::::...: :::::::..:::::.:.:::::::::::::::::::::::.:: .::
CCDS54 LMNILNKVLSKHKDLKTDGFSLDTCRSIVSVMDSDTTGKLGFEEFKYLWNNIKKWQCVYK
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE1 QFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAM
:.: :.::.. ::.: ::..::::.:::.::.::.:::..:.:.:::.::::::::::::
CCDS54 QYDRDHSGSLGSSQLRGALQAAGFQLNEQLYQMIVRRYANEDGDMDFNNFISCLVRLDAM
160 170 180 190 200 210
240 250 260
pF1KE1 FRAFKSLDKDGTGQIQVNIQEWLQLTMYS
::::::::.: : :::.:.:::::::::
CCDS54 FRAFKSLDRDRDGLIQVSIKEWLQLTMYS
220 230 240
>>CCDS45246.1 CAPN3 gene_id:825|Hs109|chr15 (309 aa)
initn: 818 init1: 744 opt: 753 Z-score: 476.2 bits: 96.0 E(33420): 3.4e-20
Smith-Waterman score: 753; 54.6% identity (80.9% similar) in 194 aa overlap (75-268:122-309)
50 60 70 80 90 100
pF1KE1 GGGGGGGGGGGGTAMRILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRL
. .:.: : . .:::: .::: .
CCDS45 FVSDRANSNKELGVDQESEEGKGKTSPDKQKQSPQPQPGSSD------QESEEQQQFRNI
100 110 120 130 140
110 120 130 140 150 160
pF1KE1 FAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEF
: :.::::::. : :: ..:: ::..: :::: :: ...::::.:.::.: .:::...::
CCDS45 FKQIAGDDMEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEF
150 160 170 180 190 200
170 180 190 200 210 220
pF1KE1 KYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNM
..:::.:: :: :.:..:::.:::: : :. .: . ::::::..::..: ::.:. :.
CCDS45 HHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNI
210 220 230 240 250 260
230 240 250 260
pF1KE1 DFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS
:::.:: :.:::..:::::...:::: : :..:. ::::::::.
CCDS45 DFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA
270 280 290 300
>>CCDS32207.1 CAPN3 gene_id:825|Hs109|chr15 (815 aa)
initn: 744 init1: 744 opt: 753 Z-score: 471.9 bits: 96.6 E(33420): 5.9e-20
Smith-Waterman score: 753; 54.6% identity (80.9% similar) in 194 aa overlap (75-268:628-815)
50 60 70 80 90 100
pF1KE1 GGGGGGGGGGGGTAMRILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRL
. .:.: : . .:::: .::: .
CCDS32 FVSDRANSNKELGVDQESEEGKGKTSPDKQKQSPQPQPGSSD------QESEEQQQFRNI
600 610 620 630 640 650
110 120 130 140 150 160
pF1KE1 FAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEF
: :.::::::. : :: ..:: ::..: :::: :: ...::::.:.::.: .:::...::
CCDS32 FKQIAGDDMEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEF
660 670 680 690 700 710
170 180 190 200 210 220
pF1KE1 KYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNM
..:::.:: :: :.:..:::.:::: : :. .: . ::::::..::..: ::.:. :.
CCDS32 HHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNI
720 730 740 750 760 770
230 240 250 260
pF1KE1 DFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS
:::.:: :.:::..:::::...:::: : :..:. ::::::::.
CCDS32 DFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA
780 790 800 810
>>CCDS45245.1 CAPN3 gene_id:825|Hs109|chr15 (821 aa)
initn: 744 init1: 744 opt: 753 Z-score: 471.9 bits: 96.6 E(33420): 6e-20
Smith-Waterman score: 753; 54.6% identity (80.9% similar) in 194 aa overlap (75-268:634-821)
50 60 70 80 90 100
pF1KE1 GGGGGGGGGGGGTAMRILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRL
. .:.: : . .:::: .::: .
CCDS45 FVSDRANSNKELGVDQESEEGKGKTSPDKQKQSPQPQPGSSD------QESEEQQQFRNI
610 620 630 640 650
110 120 130 140 150 160
pF1KE1 FAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEF
: :.::::::. : :: ..:: ::..: :::: :: ...::::.:.::.: .:::...::
CCDS45 FKQIAGDDMEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEF
660 670 680 690 700 710
170 180 190 200 210 220
pF1KE1 KYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNM
..:::.:: :: :.:..:::.:::: : :. .: . ::::::..::..: ::.:. :.
CCDS45 HHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNI
720 730 740 750 760 770
230 240 250 260
pF1KE1 DFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS
:::.:: :.:::..:::::...:::: : :..:. ::::::::.
CCDS45 DFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA
780 790 800 810 820
>>CCDS10085.1 CAPN3 gene_id:825|Hs109|chr15 (729 aa)
initn: 788 init1: 744 opt: 749 Z-score: 470.0 bits: 96.1 E(33420): 7.6e-20
Smith-Waterman score: 749; 50.9% identity (77.6% similar) in 214 aa overlap (55-268:519-729)
30 40 50 60 70 80
pF1KE1 LGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRILGGVISAISEAAAQYNPEPPPPR
: .:... . :. . . : :.
CCDS10 YINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILRVFSEKRNLSEEVENTISVDRPVPQ
490 500 510 520 530 540
90 100 110 120 130 140
pF1KE1 THYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTC
:. .:::: .::: .: :.::::::. : :: ..:: ::..: :::: :: ...:
CCDS10 PGSSD---QESEEQQQFRNIFKQIAGDDMEICADELKKVLNTVVNKHKDLKTHGFTLESC
550 560 570 580 590 600
150 160 170 180 190 200
pF1KE1 RSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFH
:::.:.::.: .:::...::..:::.:: :: :.:..:::.:::: : :. .: . ::::
CCDS10 RSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFH
610 620 630 640 650 660
210 220 230 240 250 260
pF1KE1 LNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQL
::..::..: ::.:. :.:::.:: :.:::..:::::...:::: : :..:. :::::
CCDS10 LNNQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQL
670 680 690 700 710 720
pF1KE1 TMYS
:::.
CCDS10 TMYA
>>CCDS10086.1 CAPN3 gene_id:825|Hs109|chr15 (156 aa)
initn: 729 init1: 655 opt: 655 Z-score: 420.8 bits: 84.8 E(33420): 4.2e-17
Smith-Waterman score: 655; 57.7% identity (85.3% similar) in 156 aa overlap (113-268:1-156)
90 100 110 120 130 140
pF1KE1 PRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGID
::. : :: ..:: ::..: :::: :: ..
CCDS10 MEICADELKKVLNTVVNKHKDLKTHGFTLE
10 20 30
150 160 170 180 190 200
pF1KE1 TCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAG
.::::.:.::.: .:::...::..:::.:: :: :.:..:::.:::: : :. .: . ::
CCDS10 SCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAG
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE1 FHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWL
::::..::..: ::.:. :.:::.:: :.:::..:::::...:::: : :..:. :::
CCDS10 FHLNNQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWL
100 110 120 130 140 150
pF1KE1 QLTMYS
:::::.
CCDS10 QLTMYA
>>CCDS44644.1 CAPN1 gene_id:823|Hs109|chr11 (714 aa)
initn: 621 init1: 621 opt: 634 Z-score: 401.5 bits: 83.4 E(33420): 4.9e-16
Smith-Waterman score: 634; 50.6% identity (80.5% similar) in 174 aa overlap (96-268:541-714)
70 80 90 100 110 120
pF1KE1 ISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQ-FRRLFAQLAGDDMEVSATELMNIL
::. . :. :: ::::.:::.:. :: .::
CCDS44 LRFFSEKSAGTVELDDQIQANLPDEQVLSEEEIDENFKALFRQLAGEDMEISVKELRTIL
520 530 540 550 560 570
130 140 150 160 170 180
pF1KE1 NKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTD
:.....: ::.: ::....::::: .:: : .::::. ::. ::: :. . .:...:: :
CCDS44 NRIISKHKDLRTKGFSLESCRSMVNLMDRDGNGKLGLVEFNILWNRIRNYLSIFRKFDLD
580 590 600 610 620 630
190 200 210 220 230 240
pF1KE1 RSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFK
.::.. . :. :.:.:::.::..::..:: :::. . .:::::. :::::..::: ::
CCDS44 KSGSMSAYEMRMAIESAGFKLNKKLYELIITRYSEPDLAVDFDNFVCCLVRLETMFRFFK
640 650 660 670 680 690
250 260
pF1KE1 SLDKDGTGQIQVNIQEWLQLTMYS
.:: : : . .. .::::::..
CCDS44 TLDTDLDGVVTFDLFKWLQLTMFA
700 710
>>CCDS53478.1 CAPN2 gene_id:824|Hs109|chr1 (622 aa)
initn: 680 init1: 593 opt: 606 Z-score: 385.4 bits: 80.2 E(33420): 3.9e-15
Smith-Waterman score: 606; 43.3% identity (78.6% similar) in 201 aa overlap (66-266:421-621)
40 50 60 70 80 90
pF1KE1 AGGGGGGGGGGGGGGGGGGGGTAMRILGGVISAISEAAAQYNPEPPPPRTHYSNIEANES
: ..:: :.:. ... ... .:.
CCDS53 REVLNRFKLPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISED
400 410 420 430 440 450
100 110 120 130 140 150
pF1KE1 EEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDT
. ::::::::::.: :.:: ::..:: .:.... :.:.:::.:.::. :: ..:::
CCDS53 DIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDG
460 470 480 490 500 510
160 170 180 190 200 210
pF1KE1 TGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIR
.::::..:: ::..:...: ::...:.:::::. : :. :.: :::.. .:...:.
CCDS53 SGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVA
520 530 540 550 560 570
220 230 240 250 260
pF1KE1 RYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS
:..:.. .:::::. :::::...:. ::.:: ..:: :.... :: ...
CCDS53 RFADDQLIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSVL
580 590 600 610 620
>>CCDS31035.1 CAPN2 gene_id:824|Hs109|chr1 (700 aa)
initn: 680 init1: 593 opt: 606 Z-score: 384.9 bits: 80.3 E(33420): 4.1e-15
Smith-Waterman score: 606; 43.3% identity (78.6% similar) in 201 aa overlap (66-266:499-699)
40 50 60 70 80 90
pF1KE1 AGGGGGGGGGGGGGGGGGGGGTAMRILGGVISAISEAAAQYNPEPPPPRTHYSNIEANES
: ..:: :.:. ... ... .:.
CCDS31 REVLNRFKLPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISED
470 480 490 500 510 520
100 110 120 130 140 150
pF1KE1 EEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDT
. ::::::::::.: :.:: ::..:: .:.... :.:.:::.:.::. :: ..:::
CCDS31 DIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDG
530 540 550 560 570 580
160 170 180 190 200 210
pF1KE1 TGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIR
.::::..:: ::..:...: ::...:.:::::. : :. :.: :::.. .:...:.
CCDS31 SGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVA
590 600 610 620 630 640
220 230 240 250 260
pF1KE1 RYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS
:..:.. .:::::. :::::...:. ::.:: ..:: :.... :: ...
CCDS31 RFADDQLIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSVL
650 660 670 680 690 700
268 residues in 1 query sequences
18921897 residues in 33420 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Oct 23 17:42:02 2018 done: Tue Oct 23 17:42:02 2018
Total Scan time: 1.150 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]