Result of FASTA (ccds) for
pF1KE1722
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1722, 233 aa
1>>>pF1KE1722 233 - 233 aa - 233 aa
Library: human.CCDS.faa
18921897 residues in 33420 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0286+/-0.000782; mu= 16.3047+/- 0.048
mean_var=82.7714+/-16.790, 0's: 0 Z-trim(110.1): 155 B-trim: 412 in 1/51
Lambda= 0.140972
statistics sampled from 11366 (11545) to 11366 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.724), E-opt: 0.2 (0.345), width: 16
Scan time: 1.030
The best scores are: opt bits E(33420)
CCDS35246.1 ERAS gene_id:3266|Hs109|chrX ( 233) 1598 334.2 4.5e-92
CCDS8702.1 KRAS gene_id:3845|Hs109|chr12 ( 188) 513 113.4 1e-25
CCDS877.1 NRAS gene_id:4893|Hs109|chr1 ( 189) 495 109.8 1.3e-24
CCDS8703.1 KRAS gene_id:3845|Hs109|chr12 ( 189) 484 107.6 6.2e-24
CCDS7698.1 HRAS gene_id:3265|Hs109|chr11 ( 189) 477 106.1 1.7e-23
CCDS7699.1 HRAS gene_id:3265|Hs109|chr11 ( 170) 431 96.7 1e-20
CCDS840.1 RAP1A gene_id:5906|Hs109|chr1 ( 184) 396 89.6 1.5e-18
CCDS7814.1 RRAS2 gene_id:22800|Hs109|chr11 ( 204) 386 87.7 6.5e-18
CCDS8984.1 RAP1B gene_id:5908|Hs109|chr12 ( 184) 379 86.2 1.6e-17
CCDS2131.1 RALB gene_id:5899|Hs109|chr2 ( 206) 376 85.6 2.7e-17
CCDS9485.1 RAP2A gene_id:5911|Hs109|chr13 ( 183) 372 84.8 4.4e-17
CCDS12774.1 RRAS gene_id:6237|Hs109|chr19 ( 218) 370 84.4 6.5e-17
CCDS14632.1 RAP2C gene_id:57826|Hs109|chrX ( 183) 363 82.9 1.5e-16
CCDS3100.1 MRAS gene_id:22808|Hs109|chr3 ( 208) 361 82.6 2.2e-16
CCDS3170.1 RAP2B gene_id:5912|Hs109|chr3 ( 183) 360 82.3 2.4e-16
CCDS1123.1 RIT1 gene_id:6016|Hs109|chr1 ( 219) 358 82.0 3.6e-16
CCDS58037.1 RIT1 gene_id:6016|Hs109|chr1 ( 236) 358 82.0 3.8e-16
CCDS5460.1 RALA gene_id:5898|Hs109|chr7 ( 206) 354 81.1 6e-16
CCDS11921.1 RIT2 gene_id:6014|Hs109|chr18 ( 217) 331 76.5 1.6e-14
CCDS6687.1 DIRAS2 gene_id:54769|Hs109|chr9 ( 199) 305 71.2 5.8e-13
CCDS53603.1 RRAS2 gene_id:22800|Hs109|chr11 ( 169) 290 68.0 4.3e-12
CCDS12092.1 DIRAS1 gene_id:148252|Hs109|chr19 ( 198) 287 67.5 7.4e-12
CCDS58036.1 RIT1 gene_id:6016|Hs109|chr1 ( 183) 283 66.7 1.2e-11
CCDS8778.1 RHEBL1 gene_id:121268|Hs109|chr12 ( 183) 276 65.2 3.3e-11
CCDS62431.1 RIT2 gene_id:6014|Hs109|chr18 ( 153) 269 63.7 7.8e-11
>>CCDS35246.1 ERAS gene_id:3266|Hs109|chrX (233 aa)
initn: 1598 init1: 1598 opt: 1598 Z-score: 1766.7 bits: 334.2 E(33420): 4.5e-92
Smith-Waterman score: 1598; 100.0% identity (100.0% similar) in 233 aa overlap (1-233:1-233)
10 20 30 40 50 60
pF1KE1 MELPTKPGTFDLGLATWSPSFQGETHRAQARRRDVGRQLPEYKAVVVGASGVGKSALTIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 MELPTKPGTFDLGLATWSPSFQGETHRAQARRRDVGRQLPEYKAVVVGASGVGKSALTIQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAGQAIHRALRDQCLAVCDGVLGVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 LNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAGQAIHRALRDQCLAVCDGVLGVF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ALDDPSSLIQLQQIWATWGPHPAQPLVLVGNKCDLVTTAGDAHAAAAALAHSWGAHFVET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 ALDDPSSLIQLQQIWATWGPHPAQPLVLVGNKCDLVTTAGDAHAAAAALAHSWGAHFVET
130 140 150 160 170 180
190 200 210 220 230
pF1KE1 SAKTRQGVEEAFSLLVHEIQRVQEAMAKEPMARSCREKTRHQKATCHCGCSVA
:::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 SAKTRQGVEEAFSLLVHEIQRVQEAMAKEPMARSCREKTRHQKATCHCGCSVA
190 200 210 220 230
>>CCDS8702.1 KRAS gene_id:3845|Hs109|chr12 (188 aa)
initn: 521 init1: 312 opt: 513 Z-score: 575.3 bits: 113.4 E(33420): 1e-25
Smith-Waterman score: 513; 47.3% identity (75.3% similar) in 186 aa overlap (39-220:1-184)
10 20 30 40 50 60
pF1KE1 TFDLGLATWSPSFQGETHRAQARRRDVGRQLPEYKAVVVGASGVGKSALTIQLNHQCFVE
. ::: :::::.::::::::::: .. ::.
CCDS87 MTEYKLVVVGAGGVGKSALTIQLIQNHFVD
10 20 30
70 80 90 100 110 120
pF1KE1 DHDPTIQDSYWKELTLDSGDCILNVLDTAGQAIHRALRDQCLAVCDGVLGVFALDDPSSL
..::::.::: :....:. :.:..:::::: . :.::: . . .: : :::... .:.
CCDS87 EYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSF
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 IQL----QQIWATWGPHPAQPLVLVGNKCDLVTTAGDAHAAAAALAHSWGAHFVETSAKT
.. .:: . . . :.::::::::: . . :.. : ::.:.: :.::::::
CCDS87 EDIHHYREQIKRVKDSEDV-PMVLVGNKCDLPSRTVDTKQAQD-LARSYGIPFIETSAKT
100 110 120 130 140
190 200 210 220 230
pF1KE1 RQGVEEAFSLLVHEIQRVQEAMAKEPMARSCREKTRHQKATCHCGCSVA
::::..:: ::.::.. .: :.:. .. . ::.
CCDS87 RQGVDDAFYTLVREIRKHKEKMSKDGKKKKKKSKTKCVIM
150 160 170 180
>>CCDS877.1 NRAS gene_id:4893|Hs109|chr1 (189 aa)
initn: 483 init1: 313 opt: 495 Z-score: 555.5 bits: 109.8 E(33420): 1.3e-24
Smith-Waterman score: 495; 47.5% identity (74.9% similar) in 183 aa overlap (39-215:1-181)
10 20 30 40 50 60
pF1KE1 TFDLGLATWSPSFQGETHRAQARRRDVGRQLPEYKAVVVGASGVGKSALTIQLNHQCFVE
. ::: :::::.::::::::::: .. ::.
CCDS87 MTEYKLVVVGAGGVGKSALTIQLIQNHFVD
10 20 30
70 80 90 100 110 120
pF1KE1 DHDPTIQDSYWKELTLDSGDCILNVLDTAGQAIHRALRDQCLAVCDGVLGVFALDDPSSL
..::::.::: :....:. :.:..:::::: . :.::: . . .: : :::... .:.
CCDS87 EYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSF
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 IQL----QQIWATWGPHPAQPLVLVGNKCDLVTTAGDAHAAAAALAHSWGAHFVETSAKT
.. .:: . . :.::::::::: : . :.. : ::.:.: :.::::::
CCDS87 ADINLYREQIKRVKDSDDV-PMVLVGNKCDLPTRTVDTKQAHE-LAKSYGIPFIETSAKT
100 110 120 130 140
190 200 210 220 230
pF1KE1 RQGVEEAFSLLVHEIQ--RVQEAMAKEPMARSCREKTRHQKATCHCGCSVA
:::::.:: ::.::. :... ... ...:
CCDS87 RQGVEDAFYTLVREIRQYRMKKLNSSDDGTQGCMGLPCVVM
150 160 170 180
>>CCDS8703.1 KRAS gene_id:3845|Hs109|chr12 (189 aa)
initn: 488 init1: 312 opt: 484 Z-score: 543.4 bits: 107.6 E(33420): 6.2e-24
Smith-Waterman score: 484; 47.3% identity (74.7% similar) in 182 aa overlap (39-215:1-180)
10 20 30 40 50 60
pF1KE1 TFDLGLATWSPSFQGETHRAQARRRDVGRQLPEYKAVVVGASGVGKSALTIQLNHQCFVE
. ::: :::::.::::::::::: .. ::.
CCDS87 MTEYKLVVVGAGGVGKSALTIQLIQNHFVD
10 20 30
70 80 90 100 110 120
pF1KE1 DHDPTIQDSYWKELTLDSGDCILNVLDTAGQAIHRALRDQCLAVCDGVLGVFALDDPSSL
..::::.::: :....:. :.:..:::::: . :.::: . . .: : :::... .:.
CCDS87 EYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSF
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 IQL----QQIWATWGPHPAQPLVLVGNKCDLVTTAGDAHAAAAALAHSWGAHFVETSAKT
.. .:: . . . :.::::::::: . . :.. : ::.:.: :.::::::
CCDS87 EDIHHYREQIKRVKDSEDV-PMVLVGNKCDLPSRTVDTKQAQD-LARSYGIPFIETSAKT
100 110 120 130 140
190 200 210 220 230
pF1KE1 RQGVEEAFSLLVHEIQRVQ-EAMAKEPMARSCREKTRHQKATCHCGCSVA
:: ::.:: ::.::.. . . ..:: . .:
CCDS87 RQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM
150 160 170 180
>>CCDS7698.1 HRAS gene_id:3265|Hs109|chr11 (189 aa)
initn: 495 init1: 318 opt: 477 Z-score: 535.7 bits: 106.1 E(33420): 1.7e-23
Smith-Waterman score: 477; 48.8% identity (75.3% similar) in 166 aa overlap (39-201:1-165)
10 20 30 40 50 60
pF1KE1 TFDLGLATWSPSFQGETHRAQARRRDVGRQLPEYKAVVVGASGVGKSALTIQLNHQCFVE
. ::: :::::.::::::::::: .. ::.
CCDS76 MTEYKLVVVGAGGVGKSALTIQLIQNHFVD
10 20 30
70 80 90 100 110 120
pF1KE1 DHDPTIQDSYWKELTLDSGDCILNVLDTAGQAIHRALRDQCLAVCDGVLGVFALDDPSSL
..::::.::: :....:. :.:..:::::: . :.::: . . .: : :::... .:.
CCDS76 EYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSF
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 IQLQQIWATWG---PHPAQPLVLVGNKCDLVTTAGDAHAAAAALAHSWGAHFVETSAKTR
...: :.:::::::::.. . ... : ::.:.: ..:::::::
CCDS76 EDIHQYREQIKRVKDSDDVPMVLVGNKCDLAARTVESRQAQD-LARSYGIPYIETSAKTR
100 110 120 130 140
190 200 210 220 230
pF1KE1 QGVEEAFSLLVHEIQRVQEAMAKEPMARSCREKTRHQKATCHCGCSVA
::::.:: ::.::..
CCDS76 QGVEDAFYTLVREIRQHKLRKLNPPDESGPGCMSCKCVLS
150 160 170 180
>>CCDS7699.1 HRAS gene_id:3265|Hs109|chr11 (170 aa)
initn: 451 init1: 318 opt: 431 Z-score: 485.7 bits: 96.7 E(33420): 1e-20
Smith-Waterman score: 431; 48.0% identity (74.3% similar) in 152 aa overlap (39-187:1-151)
10 20 30 40 50 60
pF1KE1 TFDLGLATWSPSFQGETHRAQARRRDVGRQLPEYKAVVVGASGVGKSALTIQLNHQCFVE
. ::: :::::.::::::::::: .. ::.
CCDS76 MTEYKLVVVGAGGVGKSALTIQLIQNHFVD
10 20 30
70 80 90 100 110 120
pF1KE1 DHDPTIQDSYWKELTLDSGDCILNVLDTAGQAIHRALRDQCLAVCDGVLGVFALDDPSSL
..::::.::: :....:. :.:..:::::: . :.::: . . .: : :::... .:.
CCDS76 EYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSF
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 IQLQQIWATWG---PHPAQPLVLVGNKCDLVTTAGDAHAAAAALAHSWGAHFVETSAKTR
...: :.:::::::::.. . ... : ::.:.: ..:::::::
CCDS76 EDIHQYREQIKRVKDSDDVPMVLVGNKCDLAARTVESRQAQD-LARSYGIPYIETSAKTR
100 110 120 130 140
190 200 210 220 230
pF1KE1 QGVEEAFSLLVHEIQRVQEAMAKEPMARSCREKTRHQKATCHCGCSVA
::
CCDS76 QGSRSGSSSSSGTLWDPPGPM
150 160 170
>>CCDS840.1 RAP1A gene_id:5906|Hs109|chr1 (184 aa)
initn: 407 init1: 263 opt: 396 Z-score: 446.8 bits: 89.6 E(33420): 1.5e-18
Smith-Waterman score: 396; 40.0% identity (66.1% similar) in 180 aa overlap (41-215:3-181)
20 30 40 50 60 70
pF1KE1 DLGLATWSPSFQGETHRAQARRRDVGRQLPEYKAVVVGASGVGKSALTIQLNHQCFVEDH
::: ::.:..::::::::.:. . ::: .
CCDS84 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKY
10 20 30
80 90 100 110 120 130
pF1KE1 DPTIQDSYWKELTLDSGDCILNVLDTAGQAIHRALRDQCLAVCDGVLGVFALDDPSSLIQ
::::.::: :.. .: .:.:..::::: :.:: . .: :... :.. .
CCDS84 DPTIEDSYRKQVEVDCQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFND
40 50 60 70 80 90
140 150 160 170 180
pF1KE1 LQ----QIWATWGPHPAQPLVLVGNKCDLVTTAGDAHAAAAALAHSW-GAHFVETSAKTR
:: :: . . . :..:::::::: .. . ::..: . :.:.:::..
CCDS84 LQDLREQILRVKDTEDV-PMILVGNKCDLEDERVVGKEQGQNLARQWCNCAFLESSAKSK
100 110 120 130 140 150
190 200 210 220 230
pF1KE1 QGVEEAFSLLVHEIQRVQEAMAKEPMARSCREKTRHQKATCHCGCSVA
.:.: : ::..:.: . :.: .::
CCDS84 INVNEIFYDLVRQINRKTPVEKKKPKKKSCLLL
160 170 180
>>CCDS7814.1 RRAS2 gene_id:22800|Hs109|chr11 (204 aa)
initn: 369 init1: 259 opt: 386 Z-score: 435.2 bits: 87.7 E(33420): 6.5e-18
Smith-Waterman score: 386; 37.7% identity (63.2% similar) in 204 aa overlap (28-228:2-201)
10 20 30 40 50 60
pF1KE1 MELPTKPGTFDLGLATWSPSFQGETHRAQARRRDVGRQLPEYKAVVVGASGVGKSALTIQ
: : :: : .:. ::::..::::::::::
CCDS78 MAAAGWRD-GSGQEKYRLVVVGGGGVGKSALTIQ
10 20 30
70 80 90 100 110 120
pF1KE1 LNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAGQAIHRALRDQCLAVCDGVLGVF
. .. :: :.::::.::: :. ..:. :..:::::: :.:.: . . .: : ::
CCDS78 FIQSYFVTDYDPTIEDSYTKQCVIDDRAARLDILDTAGQEEFGAMREQYMRTGEGFLLVF
40 50 60 70 80 90
130 140 150 160 170
pF1KE1 ALDDPSS---LIQLQQIWATWGPHPAQPLVLVGNKCDLVTTAGDAHAAAAALAHSWGAHF
.. : .: . ..:. . :..:.::: :: .. . ::.. . .
CCDS78 SVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGQQLARQLKVTY
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE1 VETSAKTRQGVEEAFSLLVHEIQRVQEAMAKEPMARSCREKTRHQKATCHCGCSVA
.:.::: :..:..:: ::. :.. :: : . :.. ..: :::
CCDS78 MEASAKIRMNVDQAFHELVRVIRKFQEQECP-PSPEPTRKE--KDKKGCHCVIF
160 170 180 190 200
>>CCDS8984.1 RAP1B gene_id:5908|Hs109|chr12 (184 aa)
initn: 374 init1: 265 opt: 379 Z-score: 428.1 bits: 86.2 E(33420): 1.6e-17
Smith-Waterman score: 379; 39.2% identity (65.2% similar) in 181 aa overlap (41-216:3-182)
20 30 40 50 60 70
pF1KE1 DLGLATWSPSFQGETHRAQARRRDVGRQLPEYKAVVVGASGVGKSALTIQLNHQCFVEDH
::: ::.:..::::::::.:. . ::: .
CCDS89 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKY
10 20 30
80 90 100 110 120 130
pF1KE1 DPTIQDSYWKELTLDSGDCILNVLDTAGQAIHRALRDQCLAVCDGVLGVFALDDPSSLIQ
::::.::: :.. .:. .:.:..::::: :.:: . .: :... :.. .
CCDS89 DPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFND
40 50 60 70 80 90
140 150 160 170 180
pF1KE1 LQ----QIWATWGPHPAQPLVLVGNKCDLVTTAGDAHAAAAALAHSWGA-HFVETSAKTR
:: :: . . :..:::::::: .. . ::..:. :.:.:::..
CCDS89 LQDLREQILRVKDTDDV-PMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSK
100 110 120 130 140 150
190 200 210 220 230
pF1KE1 QGVEEAFSLLVHEIQRVQEAMAKEPMARSCREKTRHQKATCHCGCSVA
.:.: : ::..:.: . .: ::.
CCDS89 INVNEIFYDLVRQINRKTPVPGKARKKSSCQLL
160 170 180
>>CCDS2131.1 RALB gene_id:5899|Hs109|chr2 (206 aa)
initn: 352 init1: 228 opt: 376 Z-score: 424.2 bits: 85.6 E(33420): 2.7e-17
Smith-Waterman score: 376; 36.1% identity (64.9% similar) in 194 aa overlap (39-228:12-204)
10 20 30 40 50 60
pF1KE1 TFDLGLATWSPSFQGETHRAQARRRDVGRQLPEYKAVVVGASGVGKSALTIQLNHQCFVE
: .:...::..::::::::.:. .. :::
CCDS21 MAANKSKGQSSLALHKVIMVGSGGVGKSALTLQFMYDEFVE
10 20 30 40
70 80 90 100 110 120
pF1KE1 DHDPTIQDSYWKELTLDSGDCILNVLDTAGQAIHRALRDQCLAVCDGVLGVFALDDPSSL
:..:: ::: :...::. . ...:::::: . :.::. . .: : ::.. . :.
CCDS21 DYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLLVFSITEHESF
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE1 IQL----QQIWATWGPHPAQPLVLVGNKCDLVTTAGDAHAAAAALAHSWGAHFVETSAKT
.:: . . . ::..:::: :: : . :. ::...:::::::
CCDS21 TATAEFREQILRVKAEEDKIPLLVVGNKSDLEERRQVPVEEARSKAEEWGVQYVETSAKT
110 120 130 140 150 160
190 200 210 220 230
pF1KE1 RQGVEEAFSLLVHEIQRVQEAMAKEPMARSCREKTRHQKATCHCGCSVA
: .:...: :..::. . . :. ... .. . : : :
CCDS21 RANVDKVFFDLMREIRTKKMSENKDKNGKKSSKNKKSFKERC-CLL
170 180 190 200
233 residues in 1 query sequences
18921897 residues in 33420 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Jun 19 14:28:37 2019 done: Wed Jun 19 14:28:38 2019
Total Scan time: 1.030 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]