FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1237, 420 aa
  1>>>pF1KE1237 420 - 420 aa - 420 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.5318+/-0.00119; mu= -0.0767+/- 0.072
 mean_var=286.7786+/-58.268, 0's: 0 Z-trim(111.0): 32  B-trim: 178 in 1/53
 Lambda= 0.075736
 statistics sampled from 12019 (12035) to 12019 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.706), E-opt: 0.2 (0.37), width:  16
 Scan time:  2.190

The best scores are:                                      opt bits E(32554)
CCDS41623.1 NUCB2 gene_id:4925|Hs108|chr11         ( 420) 2773 316.4 3.3e-86
CCDS81556.1 NUCB2 gene_id:4925|Hs108|chr11         ( 390) 2047 237.0 2.3e-62
CCDS12740.1 NUCB1 gene_id:4924|Hs108|chr19         ( 461) 1637 192.3 8.1e-49


>>CCDS41623.1 NUCB2 gene_id:4925|Hs108|chr11              (420 aa)
 initn: 2773 init1: 2773 opt: 2773  Z-score: 1661.3  bits: 316.4 E(32554): 3.3e-86
Smith-Waterman score: 2773; 100.0% identity (100.0% similar) in 420 aa overlap (1-420:1-420)

               10        20        30        40        50        60
pF1KE1 MRWRTILLQYCFLLITCLLTALEAVPIDIDKTKVQNIHPVESAKIEPPDTGLYYDEYLKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 MRWRTILLQYCFLLITCLLTALEAVPIDIDKTKVQNIHPVESAKIEPPDTGLYYDEYLKQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 VIDVLETDKHFREKLQKADIEEIKSGRLSKELDLVSHHVRTKLDELKRQEVGRLRMLIKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 VIDVLETDKHFREKLQKADIEEIKSGRLSKELDLVSHHVRTKLDELKRQEVGRLRMLIKA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 KLDSLQDIGMDHQALLKQFDHLNHLNPDKFESTDLDMLIKAATSDLEHYDKTRHEEFKKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 KLDSLQDIGMDHQALLKQFDHLNHLNPDKFESTDLDMLIKAATSDLEHYDKTRHEEFKKY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 EMMKEHERREYLKTLNEEKRKEEESKFEEMKKKHENHPKVNHPGSKDQLKEVWEETDGLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 EMMKEHERREYLKTLNEEKRKEEESKFEEMKKKHENHPKVNHPGSKDQLKEVWEETDGLD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 PNDFDPKTFFKLHDVNSDGFLDEQELEALFTKELEKVYDPKNEEDDMVEMEEERLRMREH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 PNDFDPKTFFKLHDVNSDGFLDEQELEALFTKELEKVYDPKNEEDDMVEMEEERLRMREH
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE1 VMNEVDTNKDRLVTLEEFLKATEKKEFLEPDSWETLDQQQFFTEEELKEYENIIALQENE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 VMNEVDTNKDRLVTLEEFLKATEKKEFLEPDSWETLDQQQFFTEEELKEYENIIALQENE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE1 LKKKADELQKQKEELQRQHDQLEAQKLEYHQVIQQMEQKKLQQGIPPSGPAGELKFEPHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 LKKKADELQKQKEELQRQHDQLEAQKLEYHQVIQQMEQKKLQQGIPPSGPAGELKFEPHI
              370       380       390       400       410       420

>>CCDS81556.1 NUCB2 gene_id:4925|Hs108|chr11              (390 aa)
 initn: 2140 init1: 2016 opt: 2047  Z-score: 1233.0  bits: 237.0 E(32554): 2.3e-62
Smith-Waterman score: 2509; 92.9% identity (92.9% similar) in 420 aa overlap (1-420:1-390)

               10        20        30        40        50        60
pF1KE1 MRWRTILLQYCFLLITCLLTALEAVPIDIDKTKVQNIHPVESAKIEPPDTGLYYDEYLKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 MRWRTILLQYCFLLITCLLTALEAVPIDIDKTKVQNIHPVESAKIEPPDTGLYYDEYLKQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 VIDVLETDKHFREKLQKADIEEIKSGRLSKELDLVSHHVRTKLDELKRQEVGRLRMLIKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 VIDVLETDKHFREKLQKADIEEIKSGRLSKELDLVSHHVRTKLDELKRQEVGRLRMLIKA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 KLDSLQDIGMDHQALLKQFDHLNHLNPDKFESTDLDMLIKAATSDLEHYDKTRHEEFKKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 KLDSLQDIGMDHQALLKQFDHLNHLNPDKFESTDLDMLIKAATSDLEHYDKTRHEEFKKY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 EMMKEHERREYLKTLNEEKRKEEESKFEEMKKKHENHPKVNHPGSKDQLKEVWEETDGLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 EMMKEHERREYLKTLNEEKRKEEESKFEEMKKKHENHPKVNHPGSKDQLKEVWEETDGLD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 PNDFDPKTFFKLHDVNSDGFLDEQELEALFTKELEKVYDPKNEEDDMVEMEEERLRMREH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 PNDFDPKTFFKLHDVNSDGFLDEQELEALFTKELEKVYDPKNEEDDMVEMEEERLRMREH
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE1 VMNEVDTNKDRLVTLEEFLKATEKKEFLEPDSWETLDQQQFFTEEELKEYENIIALQENE
       ::::                              ::::::::::::::::::::::::::
CCDS81 VMNE------------------------------TLDQQQFFTEEELKEYENIIALQENE
                                            310       320       330

              370       380       390       400       410       420
pF1KE1 LKKKADELQKQKEELQRQHDQLEAQKLEYHQVIQQMEQKKLQQGIPPSGPAGELKFEPHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 LKKKADELQKQKEELQRQHDQLEAQKLEYHQVIQQMEQKKLQQGIPPSGPAGELKFEPHI
              340       350       360       370       380       390

>>CCDS12740.1 NUCB1 gene_id:4924|Hs108|chr19              (461 aa)
 initn: 1179 init1: 985 opt: 1637  Z-score: 989.9  bits: 192.3 E(32554): 8.1e-49
Smith-Waterman score: 1637; 61.4% identity (81.9% similar) in 415 aa overlap (13-418:15-424)

                 10        20        30        40        50        
pF1KE1   MRWRTILLQYCFLLITCLLTALEAVPIDIDKTKVQNIHPVESAKIEPPDTGLYYDEYL
                     ::.  :: :. :::..    . .     :.   : ::::::: .::
CCDS12 MPPSGPRGTLLLLPLLLLLLLRAVLAVPLERGAPNKE-----ETPATESPDTGLYYHRYL
               10        20        30             40        50     

       60        70        80        90       100       110        
pF1KE1 KQVIDVLETDKHFREKLQKADIEEIKSGRLSKELDLVSHHVRTKLDELKRQEVGRLRMLI
       ..:::::::: ::::::: :. :.::::.::.:::.:::::::::::::::::.:::::.
CCDS12 QEVIDVLETDGHFREKLQAANAEDIKSGKLSRELDFVSHHVRTKLDELKRQEVSRLRMLL
          60        70        80        90       100       110     

      120         130       140       150       160       170      
pF1KE1 KAKLDSLQD--IGMDHQALLKQFDHLNHLNPDKFESTDLDMLIKAATSDLEHYDKTRHEE
       :::.:. ::  . .::  :::::.::.  :   ::. ::..::..:: :: .:: ..:::
CCDS12 KAKMDAEQDPNVQVDHLNLLKQFEHLDPQNQHTFEARDLELLIQTATRDLAQYDAAHHEE
         120       130       140       150       160       170     

        180       190       200       210       220       230      
pF1KE1 FKKYEMMKEHERREYLKTLNEEKRKEEESKFEEMKKKHENHPKVNHPGSKDQLKEVWEET
       ::.:::.::::::.::..:.::.::: : :.::....:..::::: :::. :::::::: 
CCDS12 FKRYEMLKEHERRRYLESLGEEQRKEAERKLEEQQRRHREHPKVNVPGSQAQLKEVWEEL
         180       190       200       210       220       230     

        240       250       260       270       280       290      
pF1KE1 DGLDPNDFDPKTFFKLHDVNSDGFLDEQELEALFTKELEKVYDPKNEEDDMVEMEEERLR
       :::::: :.::::: :::.:::: ::::::::::::::::::::::::::: ::::::::
CCDS12 DGLDPNRFNPKTFFILHDINSDGVLDEQELEALFTKELEKVYDPKNEEDDMREMEEERLR
         240       250       260       270       280       290     

        300       310       320       330        340       350     
pF1KE1 MREHVMNEVDTNKDRLVTLEEFLKATEKKEFLEP-DSWETLDQQQFFTEEELKEYENIIA
       ::::::..::::.:::::::::: .:..::: .  ..:::....  .:::::...:. .:
CCDS12 MREHVMKNVDTNQDRLVTLEEFLASTQRKEFGDTGEGWETVEMHPAYTEEELRRFEEELA
         300       310       320       330       340       350     

         360       370       380       390       400               
pF1KE1 LQENELKKKADELQKQKEELQRQHDQLEAQKLEYHQVIQQMEQKKLQQG------IPPSG
        .: ::. ::..:... : : :.. .::::: : .:.. .:::.: ::        : . 
CCDS12 AREAELNAKAQRLSQETEALGRSQGRLEAQKRELQQAVLHMEQRKQQQQQQQGHKAPAAH
         360       370       380       390       400       410     

     410       420                                   
pF1KE1 PAGELKFEPHI                                   
       : :.:::.:                                     
CCDS12 PEGQLKFHPDTDDVPVPAPAGDQKEVDTSEKKLLERLPEVEVPQHL
         420       430       440       450       460 




420 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 16:45:08 2016 done: Tue Nov  8 16:45:09 2016
 Total Scan time:  2.190 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]