FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1066, 492 aa
  1>>>pF1KE1066 492 - 492 aa - 492 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.8111+/-0.000361; mu= 11.9408+/- 0.022
 mean_var=128.0880+/-25.594, 0's: 0 Z-trim(117.6): 22  B-trim: 939 in 2/52
 Lambda= 0.113324
 statistics sampled from 29775 (29797) to 29775 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.706), E-opt: 0.2 (0.349), width:  16
 Scan time: 10.740

The best scores are:                                      opt bits E(85289)
NP_055739 (OMIM: 613515) beclin 1-associated autop ( 492) 3274 546.7 5.7e-155
XP_011534865 (OMIM: 613515) PREDICTED: beclin 1-as ( 379) 2496 419.4 9.1e-117


>>NP_055739 (OMIM: 613515) beclin 1-associated autophagy  (492 aa)
 initn: 3274 init1: 3274 opt: 3274  Z-score: 2903.2  bits: 546.7 E(85289): 5.7e-155
Smith-Waterman score: 3274; 100.0% identity (100.0% similar) in 492 aa overlap (1-492:1-492)

               10        20        30        40        50        60
pF1KE1 MASPSGKGARALEAPGCGPRPLARDLVDSVDDAEGLYVAVERCPLCNTTRRRLTCAKCVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MASPSGKGARALEAPGCGPRPLARDLVDSVDDAEGLYVAVERCPLCNTTRRRLTCAKCVQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 SGDFVYFDGRDRERFIDKKERLSRLKSKQEEFQKEVLKAMEGKWITDQLRWKIMSCKMRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SGDFVYFDGRDRERFIDKKERLSRLKSKQEEFQKEVLKAMEGKWITDQLRWKIMSCKMRI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 EQLKQTICKGNEEMEKNSEGLLKTKEKNQKLYSRAQRHQEKKEKIQRHNRKLGDLVEKKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EQLKQTICKGNEEMEKNSEGLLKTKEKNQKLYSRAQRHQEKKEKIQRHNRKLGDLVEKKT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 IDLRSHYERLANLRRSHILELTSVIFPIEEVKTGVRDPADVSSESDSAMTSSTVSKLAEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IDLRSHYERLANLRRSHILELTSVIFPIEEVKTGVRDPADVSSESDSAMTSSTVSKLAEA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 RRTTYLSGRWVCDDHNGDTSISITGPWISLPNNGDYSAYYSWVEEKKTTQGPDMEQSNPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RRTTYLSGRWVCDDHNGDTSISITGPWISLPNNGDYSAYYSWVEEKKTTQGPDMEQSNPA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE1 YTISAALCYATQLVNILSHILDVNLPKKLCNSEFCGENLSKQKFTRAVKKLNANILYLCF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YTISAALCYATQLVNILSHILDVNLPKKLCNSEFCGENLSKQKFTRAVKKLNANILYLCF
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE1 SQHVNLDQLQPLHTLRNLMYLVSPSSEHLGRSGPFEVRADLEESMEFVDPGVAGESDESG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SQHVNLDQLQPLHTLRNLMYLVSPSSEHLGRSGPFEVRADLEESMEFVDPGVAGESDESG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE1 DERVSDEETDLGTDWENLPSPRFCDIPSQSVEVSQSQSTQASPPIASSSAGGMISSAAAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DERVSDEETDLGTDWENLPSPRFCDIPSQSVEVSQSQSTQASPPIASSSAGGMISSAAAS
              430       440       450       460       470       480

              490  
pF1KE1 VTSWFKAYTGHR
       ::::::::::::
NP_055 VTSWFKAYTGHR
              490  

>>XP_011534865 (OMIM: 613515) PREDICTED: beclin 1-associ  (379 aa)
 initn: 2496 init1: 2496 opt: 2496  Z-score: 2217.3  bits: 419.4 E(85289): 9.1e-117
Smith-Waterman score: 2496; 100.0% identity (100.0% similar) in 379 aa overlap (114-492:1-379)

            90       100       110       120       130       140   
pF1KE1 RLKSKQEEFQKEVLKAMEGKWITDQLRWKIMSCKMRIEQLKQTICKGNEEMEKNSEGLLK
                                     ::::::::::::::::::::::::::::::
XP_011                               MSCKMRIEQLKQTICKGNEEMEKNSEGLLK
                                             10        20        30

           150       160       170       180       190       200   
pF1KE1 TKEKNQKLYSRAQRHQEKKEKIQRHNRKLGDLVEKKTIDLRSHYERLANLRRSHILELTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKEKNQKLYSRAQRHQEKKEKIQRHNRKLGDLVEKKTIDLRSHYERLANLRRSHILELTS
               40        50        60        70        80        90

           210       220       230       240       250       260   
pF1KE1 VIFPIEEVKTGVRDPADVSSESDSAMTSSTVSKLAEARRTTYLSGRWVCDDHNGDTSISI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIFPIEEVKTGVRDPADVSSESDSAMTSSTVSKLAEARRTTYLSGRWVCDDHNGDTSISI
              100       110       120       130       140       150

           270       280       290       300       310       320   
pF1KE1 TGPWISLPNNGDYSAYYSWVEEKKTTQGPDMEQSNPAYTISAALCYATQLVNILSHILDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGPWISLPNNGDYSAYYSWVEEKKTTQGPDMEQSNPAYTISAALCYATQLVNILSHILDV
              160       170       180       190       200       210

           330       340       350       360       370       380   
pF1KE1 NLPKKLCNSEFCGENLSKQKFTRAVKKLNANILYLCFSQHVNLDQLQPLHTLRNLMYLVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLPKKLCNSEFCGENLSKQKFTRAVKKLNANILYLCFSQHVNLDQLQPLHTLRNLMYLVS
              220       230       240       250       260       270

           390       400       410       420       430       440   
pF1KE1 PSSEHLGRSGPFEVRADLEESMEFVDPGVAGESDESGDERVSDEETDLGTDWENLPSPRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSSEHLGRSGPFEVRADLEESMEFVDPGVAGESDESGDERVSDEETDLGTDWENLPSPRF
              280       290       300       310       320       330

           450       460       470       480       490  
pF1KE1 CDIPSQSVEVSQSQSTQASPPIASSSAGGMISSAAASVTSWFKAYTGHR
       :::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CDIPSQSVEVSQSQSTQASPPIASSSAGGMISSAAASVTSWFKAYTGHR
              340       350       360       370         




492 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 20:12:51 2016 done: Sat Nov  5 20:12:52 2016
 Total Scan time: 10.740 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]