Result of FASTA (omim) for
pF1KE1051
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1051, 445 aa
1>>>pF1KE1051 445 - 445 aa - 445 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8249+/-0.000324; mu= 15.5287+/- 0.020
mean_var=77.0679+/-15.537, 0's: 0 Z-trim(116.5): 59 B-trim: 41 in 1/50
Lambda= 0.146096
statistics sampled from 27666 (27727) to 27666 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.678), E-opt: 0.2 (0.325), width: 16
Scan time: 8.750
The best scores are: opt bits E(85289)
NP_068373 (OMIM: 606150) fatty acid desaturase 3 [ ( 445) 3152 673.6 2.8e-193
XP_011543325 (OMIM: 606150) PREDICTED: fatty acid ( 454) 2754 589.8 5e-168
XP_016873213 (OMIM: 606150) PREDICTED: fatty acid ( 491) 2628 563.2 5.3e-160
XP_016873212 (OMIM: 606150) PREDICTED: fatty acid ( 500) 2230 479.3 9.6e-135
NP_004256 (OMIM: 606149) fatty acid desaturase 2 i ( 444) 2051 441.6 2e-123
NP_001268431 (OMIM: 606149) fatty acid desaturase ( 413) 1791 386.8 5.9e-107
NP_001268430 (OMIM: 606149) fatty acid desaturase ( 422) 1791 386.8 6e-107
NP_037534 (OMIM: 606148) fatty acid desaturase 1 [ ( 501) 1682 363.8 5.7e-100
XP_011543324 (OMIM: 606148) PREDICTED: fatty acid ( 430) 1481 321.4 2.8e-87
NP_001905 (OMIM: 250790,613218) cytochrome b5 isof ( 98) 178 46.5 3.8e-05
XP_011524137 (OMIM: 250790,613218) PREDICTED: cyto ( 98) 178 46.5 3.8e-05
NP_683725 (OMIM: 250790,613218) cytochrome b5 isof ( 134) 178 46.5 4.9e-05
NP_001177736 (OMIM: 250790,613218) cytochrome b5 i ( 124) 174 45.7 8.3e-05
NP_085056 (OMIM: 611964) cytochrome b5 type B [Hom ( 150) 152 41.1 0.0024
>>NP_068373 (OMIM: 606150) fatty acid desaturase 3 [Homo (445 aa)
initn: 3152 init1: 3152 opt: 3152 Z-score: 3591.1 bits: 673.6 E(85289): 2.8e-193
Smith-Waterman score: 3152; 100.0% identity (100.0% similar) in 445 aa overlap (1-445:1-445)
10 20 30 40 50 60
pF1KE1 MGGVGEPGPREGPAQPGAPLPTFCWEQIRAHDQPGDKWLVIERRVYDISRWAQRHPGGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 MGGVGEPGPREGPAQPGAPLPTFCWEQIRAHDQPGDKWLVIERRVYDISRWAQRHPGGSR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LIGHHGAEDATDAFRAFHQDLNFVRKFLQPLLIGELAPEEPSQDGPLNAQLVEDFRALHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 LIGHHGAEDATDAFRAFHQDLNFVRKFLQPLLIGELAPEEPSQDGPLNAQLVEDFRALHQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 AAEDMKLFDASPTFFAFLLGHILAMEVLAWLLIYLLGPGWVPSALAAFILAISQAQSWCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 AAEDMKLFDASPTFFAFLLGHILAMEVLAWLLIYLLGPGWVPSALAAFILAISQAQSWCL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 QHDLGHASIFKKSWWNHVAQKFVMGQLKGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 QHDLGHASIFKKSWWNHVAQKFVMGQLKGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAPV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 FLLGESSVEYGKKKRRYLPYNQQHLYFFLIGPPLLTLVNFEVENLAYMLVCMQWADLLWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 FLLGESSVEYGKKKRRYLPYNQQHLYFFLIGPPLLTLVNFEVENLAYMLVCMQWADLLWA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 ASFYARFFLSYLPFYGVPGVLLFFVAVRVLESHWFVWITQMNHIPKEIGHEKHRDWVSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 ASFYARFFLSYLPFYGVPGVLLFFVAVRVLESHWFVWITQMNHIPKEIGHEKHRDWVSSQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 LAATCNVEPSLFTNWFSGHLNFQIEHHLFPRMPRHNYSRVAPLVKSLCAKHGLSYEVKPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 LAATCNVEPSLFTNWFSGHLNFQIEHHLFPRMPRHNYSRVAPLVKSLCAKHGLSYEVKPF
370 380 390 400 410 420
430 440
pF1KE1 LTALVDIVRSLKKSGDIWLDAYLHQ
:::::::::::::::::::::::::
NP_068 LTALVDIVRSLKKSGDIWLDAYLHQ
430 440
>>XP_011543325 (OMIM: 606150) PREDICTED: fatty acid desa (454 aa)
initn: 3158 init1: 2750 opt: 2754 Z-score: 3137.6 bits: 589.8 E(85289): 5e-168
Smith-Waterman score: 3115; 97.8% identity (98.0% similar) in 454 aa overlap (1-445:1-454)
10 20 30 40 50 60
pF1KE1 MGGVGEPGPREGPAQPGAPLPTFCWEQIRAHDQPGDKWLVIERRVYDISRWAQRHPGGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGGVGEPGPREGPAQPGAPLPTFCWEQIRAHDQPGDKWLVIERRVYDISRWAQRHPGGSR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LIGHHGAEDATDAFRAFHQDLNFVRKFLQPLLIGELAPEEPSQDGPLNAQLVEDFRALHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIGHHGAEDATDAFRAFHQDLNFVRKFLQPLLIGELAPEEPSQDGPLNAQLVEDFRALHQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 AAEDMKLFDASPTFFAFLLGHILAMEVLAWLLIYLLGPGWVPSALAAFILAISQAQSWCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAEDMKLFDASPTFFAFLLGHILAMEVLAWLLIYLLGPGWVPSALAAFILAISQAQSWCL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 QHDLGHASIFKKSWWNHVAQKFVMGQLKGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHDLGHASIFKKSWWNHVAQKFVMGQLKGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAPV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 FLLGESSVEYGKKKRRYLPYNQQHLYFFLIGPPLLTLVNFEVENLAYMLVCMQWADLLWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLLGESSVEYGKKKRRYLPYNQQHLYFFLIGPPLLTLVNFEVENLAYMLVCMQWADLLWA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 ASFYARFFLSYLPFYGVPGVLLFFVAVRVLESHWFVWITQMNHIPKEIGHEKHRDWVSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASFYARFFLSYLPFYGVPGVLLFFVAVRVLESHWFVWITQMNHIPKEIGHEKHRDWVSSQ
310 320 330 340 350 360
370 380 390 400 410
pF1KE1 LAATCNVEPSLFTNWFSGHLNFQIEHH---------LFPRMPRHNYSRVAPLVKSLCAKH
::::::::::::::::::::::::::. ::::::::::::::::::::::::
XP_011 LAATCNVEPSLFTNWFSGHLNFQIEHQCQHTLPTPSLFPRMPRHNYSRVAPLVKSLCAKH
370 380 390 400 410 420
420 430 440
pF1KE1 GLSYEVKPFLTALVDIVRSLKKSGDIWLDAYLHQ
::::::::::::::::::::::::::::::::::
XP_011 GLSYEVKPFLTALVDIVRSLKKSGDIWLDAYLHQ
430 440 450
>>XP_016873213 (OMIM: 606150) PREDICTED: fatty acid desa (491 aa)
initn: 2628 init1: 2628 opt: 2628 Z-score: 2993.5 bits: 563.2 E(85289): 5.3e-160
Smith-Waterman score: 2628; 97.4% identity (97.9% similar) in 388 aa overlap (58-445:104-491)
30 40 50 60 70 80
pF1KE1 IRAHDQPGDKWLVIERRVYDISRWAQRHPGGSRLIGHHGAEDATDAFRAFHQDLNFVRKF
::: :. . ::::::::::::::::
XP_016 PPLGALDLTLQDARLEAPQAPLLTDRDSASGSRGRGEALRDAQQDAFRAFHQDLNFVRKF
80 90 100 110 120 130
90 100 110 120 130 140
pF1KE1 LQPLLIGELAPEEPSQDGPLNAQLVEDFRALHQAAEDMKLFDASPTFFAFLLGHILAMEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQPLLIGELAPEEPSQDGPLNAQLVEDFRALHQAAEDMKLFDASPTFFAFLLGHILAMEV
140 150 160 170 180 190
150 160 170 180 190 200
pF1KE1 LAWLLIYLLGPGWVPSALAAFILAISQAQSWCLQHDLGHASIFKKSWWNHVAQKFVMGQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAWLLIYLLGPGWVPSALAAFILAISQAQSWCLQHDLGHASIFKKSWWNHVAQKFVMGQL
200 210 220 230 240 250
210 220 230 240 250 260
pF1KE1 KGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAPVFLLGESSVEYGKKKRRYLPYNQQHLYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAPVFLLGESSVEYGKKKRRYLPYNQQHLYF
260 270 280 290 300 310
270 280 290 300 310 320
pF1KE1 FLIGPPLLTLVNFEVENLAYMLVCMQWADLLWAASFYARFFLSYLPFYGVPGVLLFFVAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLIGPPLLTLVNFEVENLAYMLVCMQWADLLWAASFYARFFLSYLPFYGVPGVLLFFVAV
320 330 340 350 360 370
330 340 350 360 370 380
pF1KE1 RVLESHWFVWITQMNHIPKEIGHEKHRDWVSSQLAATCNVEPSLFTNWFSGHLNFQIEHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVLESHWFVWITQMNHIPKEIGHEKHRDWVSSQLAATCNVEPSLFTNWFSGHLNFQIEHH
380 390 400 410 420 430
390 400 410 420 430 440
pF1KE1 LFPRMPRHNYSRVAPLVKSLCAKHGLSYEVKPFLTALVDIVRSLKKSGDIWLDAYLHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFPRMPRHNYSRVAPLVKSLCAKHGLSYEVKPFLTALVDIVRSLKKSGDIWLDAYLHQ
440 450 460 470 480 490
>>XP_016873212 (OMIM: 606150) PREDICTED: fatty acid desa (500 aa)
initn: 2658 init1: 2226 opt: 2230 Z-score: 2540.0 bits: 479.3 E(85289): 9.6e-135
Smith-Waterman score: 2591; 95.0% identity (95.7% similar) in 397 aa overlap (58-445:104-500)
30 40 50 60 70 80
pF1KE1 IRAHDQPGDKWLVIERRVYDISRWAQRHPGGSRLIGHHGAEDATDAFRAFHQDLNFVRKF
::: :. . ::::::::::::::::
XP_016 PPLGALDLTLQDARLEAPQAPLLTDRDSASGSRGRGEALRDAQQDAFRAFHQDLNFVRKF
80 90 100 110 120 130
90 100 110 120 130 140
pF1KE1 LQPLLIGELAPEEPSQDGPLNAQLVEDFRALHQAAEDMKLFDASPTFFAFLLGHILAMEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQPLLIGELAPEEPSQDGPLNAQLVEDFRALHQAAEDMKLFDASPTFFAFLLGHILAMEV
140 150 160 170 180 190
150 160 170 180 190 200
pF1KE1 LAWLLIYLLGPGWVPSALAAFILAISQAQSWCLQHDLGHASIFKKSWWNHVAQKFVMGQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAWLLIYLLGPGWVPSALAAFILAISQAQSWCLQHDLGHASIFKKSWWNHVAQKFVMGQL
200 210 220 230 240 250
210 220 230 240 250 260
pF1KE1 KGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAPVFLLGESSVEYGKKKRRYLPYNQQHLYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAPVFLLGESSVEYGKKKRRYLPYNQQHLYF
260 270 280 290 300 310
270 280 290 300 310 320
pF1KE1 FLIGPPLLTLVNFEVENLAYMLVCMQWADLLWAASFYARFFLSYLPFYGVPGVLLFFVAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLIGPPLLTLVNFEVENLAYMLVCMQWADLLWAASFYARFFLSYLPFYGVPGVLLFFVAV
320 330 340 350 360 370
330 340 350 360 370 380
pF1KE1 RVLESHWFVWITQMNHIPKEIGHEKHRDWVSSQLAATCNVEPSLFTNWFSGHLNFQIEHH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_016 RVLESHWFVWITQMNHIPKEIGHEKHRDWVSSQLAATCNVEPSLFTNWFSGHLNFQIEHQ
380 390 400 410 420 430
390 400 410 420 430
pF1KE1 ---------LFPRMPRHNYSRVAPLVKSLCAKHGLSYEVKPFLTALVDIVRSLKKSGDIW
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CQHTLPTPSLFPRMPRHNYSRVAPLVKSLCAKHGLSYEVKPFLTALVDIVRSLKKSGDIW
440 450 460 470 480 490
440
pF1KE1 LDAYLHQ
:::::::
XP_016 LDAYLHQ
500
>>NP_004256 (OMIM: 606149) fatty acid desaturase 2 isofo (444 aa)
initn: 2076 init1: 1064 opt: 2051 Z-score: 2336.9 bits: 441.6 E(85289): 2e-123
Smith-Waterman score: 2051; 62.6% identity (84.1% similar) in 446 aa overlap (1-445:1-444)
10 20 30 40 50 60
pF1KE1 MGGVGEPGPREGPAQPGAPLPTFCWEQIRAHDQPGDKWLVIERRVYDISRWAQRHPGGSR
:: :. : :: :. . .::: ::.:. :. :.::::.:.::.:..:. .::::.:
NP_004 MGKGGNQG--EGAAEREVSVPTFSWEEIQKHNLRTDRWLVIDRKVYNITKWSIQHPGGQR
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 LIGHHGAEDATDAFRAFHQDLNFVRKFLQPLLIGELAPEEPSQDGPLNAQLVEDFRALHQ
.:::...::::::::::: ::.:: :::.::::::::::::::: :....::::::..
NP_004 VIGHYAGEDATDAFRAFHPDLEFVGKFLKPLLIGELAPEEPSQDHGKNSKITEDFRALRK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 AAEDMKLFDASPTFFAFLLGHILAMEVLAWLLIYLLGPGWVPSALAAFILAISQAQSWCL
.::::.:: .. .:: .::.::.:.: .::. .. .: ::.:. ..::.:: ::::. :
NP_004 TAEDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGWL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 QHDLGHASIFKKSWWNHVAQKFVMGQLKGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAPV
::: :: :...: :::...:::.:.::: ::.::: ::::::::::::::::::.. :
NP_004 QHDYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDVNMLHV
180 190 200 210 220 230
250 260 270 280 290
pF1KE1 FLLGE-SSVEYGKKKRRYLPYNQQHLYFFLIGPPLLTLVNFEVENLAYMLVCMQWADLLW
:.::: . .:::::: .:::::.:: :::::::::: . :. . . :.: .:.:: :
NP_004 FVLGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAW
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE1 AASFYARFFLSYLPFYGVPGVLLFFVAVRVLESHWFVWITQMNHIPKEIGHEKHRDWVSS
:.:.: :::..:.::::. :.:::. .: ::::::::.:::::: :: .: .::: ::
NP_004 AVSYYIRFFITYIPFYGILGALLFLNFIRFLESHWFVWVTQMNHIVMEIDQEAYRDWFSS
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE1 QLAATCNVEPSLFTNWFSGHLNFQIEHHLFPRMPRHNYSRVAPLVKSLCAKHGLSYEVKP
::.:::::: :.:..:::::::::::::::: ::::: ..::::::::::::. :. ::
NP_004 QLTATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKP
360 370 380 390 400 410
420 430 440
pF1KE1 FLTALVDIVRSLKKSGDIWLDAYLHQ
.: ::.::.::::::: .:::::::.
NP_004 LLRALLDIIRSLKKSGKLWLDAYLHK
420 430 440
>>NP_001268431 (OMIM: 606149) fatty acid desaturase 2 is (413 aa)
initn: 1826 init1: 986 opt: 1791 Z-score: 2041.2 bits: 386.8 E(85289): 5.9e-107
Smith-Waterman score: 1791; 64.2% identity (84.7% similar) in 380 aa overlap (67-445:34-413)
40 50 60 70 80 90
pF1KE1 KWLVIERRVYDISRWAQRHPGGSRLIGHHGAEDATDAFRAFHQDLNFVRKFLQPLLIGEL
: .. ::::::: ::.:: :::.:::::::
NP_001 EPPGCRRVNSLMLYTLRSITSHRSSHPERWATSSQDAFRAFHPDLEFVGKFLKPLLIGEL
10 20 30 40 50 60
100 110 120 130 140 150
pF1KE1 APEEPSQDGPLNAQLVEDFRALHQAAEDMKLFDASPTFFAFLLGHILAMEVLAWLLIYLL
:::::::: :....::::::...::::.:: .. .:: .::.::.:.: .::. .. .
NP_001 APEEPSQDHGKNSKITEDFRALRKTAEDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYF
70 80 90 100 110 120
160 170 180 190 200 210
pF1KE1 GPGWVPSALAAFILAISQAQSWCLQHDLGHASIFKKSWWNHVAQKFVMGQLKGFSAHWWN
: ::.:. ..::.:: ::::. :::: :: :...: :::...:::.:.::: ::.:::
NP_001 GNGWIPTLITAFVLATSQAQAGWLQHDYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWN
130 140 150 160 170 180
220 230 240 250 260 270
pF1KE1 FRHFQHHAKPNIFHKDPDVTVAPVFLLGE-SSVEYGKKKRRYLPYNQQHLYFFLIGPPLL
::::::::::::::::::.. ::.::: . .:::::: .:::::.:: ::::::::::
NP_001 HRHFQHHAKPNIFHKDPDVNMLHVFVLGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLL
190 200 210 220 230 240
280 290 300 310 320 330
pF1KE1 TLVNFEVENLAYMLVCMQWADLLWAASFYARFFLSYLPFYGVPGVLLFFVAVRVLESHWF
. :. . . :.: .:.:: ::.:.: :::..:.::::. :.:::. .: ::::::
NP_001 IPMYFQYQIIMTMIVHKNWVDLAWAVSYYIRFFITYIPFYGILGALLFLNFIRFLESHWF
250 260 270 280 290 300
340 350 360 370 380 390
pF1KE1 VWITQMNHIPKEIGHEKHRDWVSSQLAATCNVEPSLFTNWFSGHLNFQIEHHLFPRMPRH
::.:::::: :: .: .::: ::::.:::::: :.:..:::::::::::::::: ::::
NP_001 VWVTQMNHIVMEIDQEAYRDWFSSQLTATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRH
310 320 330 340 350 360
400 410 420 430 440
pF1KE1 NYSRVAPLVKSLCAKHGLSYEVKPFLTALVDIVRSLKKSGDIWLDAYLHQ
: ..::::::::::::. :. ::.: ::.::.::::::: .:::::::.
NP_001 NLHKIAPLVKSLCAKHGIEYQEKPLLRALLDIIRSLKKSGKLWLDAYLHK
370 380 390 400 410
>>NP_001268430 (OMIM: 606149) fatty acid desaturase 2 is (422 aa)
initn: 1822 init1: 986 opt: 1791 Z-score: 2041.1 bits: 386.8 E(85289): 6e-107
Smith-Waterman score: 1791; 63.0% identity (83.2% similar) in 392 aa overlap (55-445:35-422)
30 40 50 60 70 80
pF1KE1 WEQIRAHDQPGDKWLVIERRVYDISRWAQRHPGGSRLIGHHGAEDATDAFRAFHQDLNFV
::... :: ::::::: ::.::
NP_001 EAGPFVCVCVLLASIPTPQTPLLQASLPPFHPASA---GHP-ITGQQDAFRAFHPDLEFV
10 20 30 40 50 60
90 100 110 120 130 140
pF1KE1 RKFLQPLLIGELAPEEPSQDGPLNAQLVEDFRALHQAAEDMKLFDASPTFFAFLLGHILA
:::.::::::::::::::: :....::::::...::::.:: .. .:: .::.::.:
NP_001 GKFLKPLLIGELAPEEPSQDHGKNSKITEDFRALRKTAEDMNLFKTNHVFFLLLLAHIIA
70 80 90 100 110 120
150 160 170 180 190 200
pF1KE1 MEVLAWLLIYLLGPGWVPSALAAFILAISQAQSWCLQHDLGHASIFKKSWWNHVAQKFVM
.: .::. .. .: ::.:. ..::.:: ::::. :::: :: :...: :::...:::.
NP_001 LESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGWLQHDYGHLSVYRKPKWNHLVHKFVI
130 140 150 160 170 180
210 220 230 240 250 260
pF1KE1 GQLKGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAPVFLLGE-SSVEYGKKKRRYLPYNQQ
:.::: ::.::: ::::::::::::::::::.. ::.::: . .:::::: .:::::.:
NP_001 GHLKGASANWWNHRHFQHHAKPNIFHKDPDVNMLHVFVLGEWQPIEYGKKKLKYLPYNHQ
190 200 210 220 230 240
270 280 290 300 310 320
pF1KE1 HLYFFLIGPPLLTLVNFEVENLAYMLVCMQWADLLWAASFYARFFLSYLPFYGVPGVLLF
: :::::::::: . :. . . :.: .:.:: ::.:.: :::..:.::::. :.:::
NP_001 HEYFFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAWAVSYYIRFFITYIPFYGILGALLF
250 260 270 280 290 300
330 340 350 360 370 380
pF1KE1 FVAVRVLESHWFVWITQMNHIPKEIGHEKHRDWVSSQLAATCNVEPSLFTNWFSGHLNFQ
. .: ::::::::.:::::: :: .: .::: ::::.:::::: :.:..:::::::::
NP_001 LNFIRFLESHWFVWVTQMNHIVMEIDQEAYRDWFSSQLTATCNVEQSFFNDWFSGHLNFQ
310 320 330 340 350 360
390 400 410 420 430 440
pF1KE1 IEHHLFPRMPRHNYSRVAPLVKSLCAKHGLSYEVKPFLTALVDIVRSLKKSGDIWLDAYL
::::::: ::::: ..::::::::::::. :. ::.: ::.::.::::::: .::::::
NP_001 IEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLLRALLDIIRSLKKSGKLWLDAYL
370 380 390 400 410 420
pF1KE1 HQ
:.
NP_001 HK
>>NP_037534 (OMIM: 606148) fatty acid desaturase 1 [Homo (501 aa)
initn: 1719 init1: 922 opt: 1682 Z-score: 1915.8 bits: 363.8 E(85289): 5.7e-100
Smith-Waterman score: 1682; 52.4% identity (78.2% similar) in 450 aa overlap (3-445:52-501)
10 20
pF1KE1 MGGVGEPGPREGP--AQPGAPLPT---FCWEQ
::..:. : :. .: :: : :..
NP_037 RLALGARQQIHSWSPRTPSTRLTAPAGPARGVARPAMAPDPVAAETAAQGPTPRYFTWDE
30 40 50 60 70 80
30 40 50 60 70 80
pF1KE1 IRAHDQPGDKWLVIERRVYDISRWAQRHPGGSRLIGHHGAEDATDAFRAFHQDLNFVRKF
. .. ..::::.:.::.::....:::::::.:.:....:::: : ::: . ..:.:.
NP_037 VAQRSGCEERWLVIDRKVYNISEFTRRHPGGSRVISHYAGQDATDPFVAFHINKGLVKKY
90 100 110 120 130 140
90 100 110 120 130 140
pF1KE1 LQPLLIGELAPEEPSQDGPLNAQLVEDFRALHQAAEDMKLFDASPTFFAFLLGHILAMEV
.. ::::::.::.:: . : .:...:: :. ..: : :. :. .:: . : ::: ..
NP_037 MNSLLIGELSPEQPSFEPTKNKELTDEFRELRATVERMGLMKANHVFFLLYLLHILLLDG
150 160 170 180 190 200
150 160 170 180 190 200
pF1KE1 LAWLLIYLLGPGWVPSALAAFILAISQAQSWCLQHDLGHASIFKKSWWNHVAQKFVMGQL
::: ....: ...: : : .:. :::. ::::.:: :.:. : :::. ..::.:.:
NP_037 AAWLTLWVFGTSFLPFLLCAVLLSAVQAQAGWLQHDFGHLSVFSTSKWNHLLHHFVIGHL
210 220 230 240 250 260
210 220 230 240 250 260
pF1KE1 KGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAPVFL-LGES-SVEYGKKKRRYLPYNQQHL
:: : ::: ::::::::: :.::::... : :. ::. ::: ::.:..:.:::.::
NP_037 KGAPASWWNHMHFQHHAKPNCFRKDPDINMHPFFFALGKILSVELGKQKKKYMPYNHQHK
270 280 290 300 310 320
270 280 290 300 310 320
pF1KE1 YFFLIGPPLLTLVNFEVENLAYMLVCMQWADLLWAASFYARFFLSYLPFYGVPGVLLFFV
:::::::: : . :. . ... .:.:: : .::.::::.:.:. :. . : .:
NP_037 YFFLIGPPALLPLYFQWYIFYFVIQRKKWVDLAWMITFYVRFFLTYVPLLGLKAFLGLFF
330 340 350 360 370 380
330 340 350 360 370 380
pF1KE1 AVRVLESHWFVWITQMNHIPKEIGHEKHRDWVSSQLAATCNVEPSLFTNWFSGHLNFQIE
:: :::.::::.::::::: .: :... ::::.:: :::::. : :..:::::::::::
NP_037 IVRFLESNWFVWVTQMNHIPMHIDHDRNMDWVSTQLQATCNVHKSAFNDWFSGHLNFQIE
390 400 410 420 430 440
390 400 410 420 430 440
pF1KE1 HHLFPRMPRHNYSRVAPLVKSLCAKHGLSYEVKPFLTALVDIVRSLKKSGDIWLDAYLHQ
::::: :::::: .:::::.:::::::. :. ::.:.:..::..:::.::..::::::::
NP_037 HHLFPTMPRHNYHKVAPLVQSLCAKHGIEYQSKPLLSAFADIIHSLKESGQLWLDAYLHQ
450 460 470 480 490 500
>>XP_011543324 (OMIM: 606148) PREDICTED: fatty acid desa (430 aa)
initn: 1515 init1: 922 opt: 1481 Z-score: 1687.9 bits: 321.4 E(85289): 2.8e-87
Smith-Waterman score: 1481; 54.0% identity (77.7% similar) in 385 aa overlap (65-445:46-430)
40 50 60 70 80 90
pF1KE1 GDKWLVIERRVYDISRWAQRHPGGSRLIGHHGAEDAT--DAFRAFHQDLNFVRKFLQPLL
:: : : : ::: . ..:.:... ::
XP_011 GRRLRPGPRPTRRITYRARGCRTCQRESYRHGPYLAQPKDPFVAFHINKGLVKKYMNSLL
20 30 40 50 60 70
100 110 120 130 140 150
pF1KE1 IGELAPEEPSQDGPLNAQLVEDFRALHQAAEDMKLFDASPTFFAFLLGHILAMEVLAWLL
::::.::.:: . : .:...:: :. ..: : :. :. .:: . : ::: .. :::
XP_011 IGELSPEQPSFEPTKNKELTDEFRELRATVERMGLMKANHVFFLLYLLHILLLDGAAWLT
80 90 100 110 120 130
160 170 180 190 200 210
pF1KE1 IYLLGPGWVPSALAAFILAISQAQSWCLQHDLGHASIFKKSWWNHVAQKFVMGQLKGFSA
....: ...: : : .:. :::. ::::.:: :.:. : :::. ..::.:.::: :
XP_011 LWVFGTSFLPFLLCAVLLSAVQAQAGWLQHDFGHLSVFSTSKWNHLLHHFVIGHLKGAPA
140 150 160 170 180 190
220 230 240 250 260 270
pF1KE1 HWWNFRHFQHHAKPNIFHKDPDVTVAPVFL-LGES-SVEYGKKKRRYLPYNQQHLYFFLI
::: ::::::::: :.::::... : :. ::. ::: ::.:..:.:::.:: :::::
XP_011 SWWNHMHFQHHAKPNCFRKDPDINMHPFFFALGKILSVELGKQKKKYMPYNHQHKYFFLI
200 210 220 230 240 250
280 290 300 310 320 330
pF1KE1 GPPLLTLVNFEVENLAYMLVCMQWADLLWAASFYARFFLSYLPFYGVPGVLLFFVAVRVL
::: : . :. . ... .:.:: : .::.::::.:.:. :. . : .: :: :
XP_011 GPPALLPLYFQWYIFYFVIQRKKWVDLAWMITFYVRFFLTYVPLLGLKAFLGLFFIVRFL
260 270 280 290 300 310
340 350 360 370 380 390
pF1KE1 ESHWFVWITQMNHIPKEIGHEKHRDWVSSQLAATCNVEPSLFTNWFSGHLNFQIEHHLFP
::.::::.::::::: .: :... ::::.:: :::::. : :..::::::::::::::::
XP_011 ESNWFVWVTQMNHIPMHIDHDRNMDWVSTQLQATCNVHKSAFNDWFSGHLNFQIEHHLFP
320 330 340 350 360 370
400 410 420 430 440
pF1KE1 RMPRHNYSRVAPLVKSLCAKHGLSYEVKPFLTALVDIVRSLKKSGDIWLDAYLHQ
:::::: .:::::.:::::::. :. ::.:.:..::..:::.::..::::::::
XP_011 TMPRHNYHKVAPLVQSLCAKHGIEYQSKPLLSAFADIIHSLKESGQLWLDAYLHQ
380 390 400 410 420 430
>>NP_001905 (OMIM: 250790,613218) cytochrome b5 isoform (98 aa)
initn: 159 init1: 118 opt: 178 Z-score: 213.4 bits: 46.5 E(85289): 3.8e-05
Smith-Waterman score: 178; 26.9% identity (69.9% similar) in 93 aa overlap (15-106:4-95)
10 20 30 40 50 60
pF1KE1 MGGVGEPGPREGPAQPGAPLPTFCWEQIRAHDQPGDKWLVIERRVYDISRWAQRHPGGSR
: . . :.:. :.. . ::.....:::.... ..:::: .
NP_001 MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEE
10 20 30 40
70 80 90 100 110
pF1KE1 LIGHHGAEDATDAFRAFHQDLNFVRKFLQPLLIGELAPEE-PSQDGPLNAQLVEDFRALH
.. .... :::. :. .. . .:.. . ..:::: :.. :. . :
NP_001 VLREQAGGDATENFEDVGHSTD-AREMSKTFIIGELHPDDRPKLNKPPEP
50 60 70 80 90
120 130 140 150 160 170
pF1KE1 QAAEDMKLFDASPTFFAFLLGHILAMEVLAWLLIYLLGPGWVPSALAAFILAISQAQSWC
445 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 07:49:18 2016 done: Sat Nov 5 07:49:19 2016
Total Scan time: 8.750 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]