Result of FASTA (omim) for
pF1KE1048
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1048, 397 aa
1>>>pF1KE1048 397 - 397 aa - 397 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5560+/-0.000386; mu= 15.7128+/- 0.024
mean_var=65.7360+/-13.215, 0's: 0 Z-trim(112.2): 26 B-trim: 1066 in 1/53
Lambda= 0.158188
statistics sampled from 20981 (21007) to 20981 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.626), E-opt: 0.2 (0.246), width: 16
Scan time: 8.640
The best scores are: opt bits E(85289)
NP_006102 (OMIM: 604770) 3-ketoacyl-CoA thiolase, ( 397) 2580 597.7 1.5e-170
NP_005882 (OMIM: 100678,614055) acetyl-CoA acetylt ( 397) 1004 238.1 2.9e-62
NP_001290182 (OMIM: 100678,614055) acetyl-CoA acet ( 426) 969 230.1 7.8e-60
NP_000010 (OMIM: 203750,607809) acetyl-CoA acetylt ( 427) 876 208.9 1.9e-53
NP_001598 (OMIM: 604054) 3-ketoacyl-CoA thiolase, ( 424) 805 192.7 1.4e-48
XP_016873170 (OMIM: 203750,607809) PREDICTED: acet ( 337) 785 188.1 2.8e-47
XP_006718898 (OMIM: 203750,607809) PREDICTED: acet ( 337) 785 188.1 2.8e-47
XP_016873172 (OMIM: 203750,607809) PREDICTED: acet ( 301) 675 162.9 9.1e-40
XP_016873171 (OMIM: 203750,607809) PREDICTED: acet ( 301) 675 162.9 9.1e-40
XP_006713186 (OMIM: 604054) PREDICTED: 3-ketoacyl- ( 272) 656 158.6 1.7e-38
XP_011531952 (OMIM: 604054) PREDICTED: 3-ketoacyl- ( 279) 656 158.6 1.7e-38
NP_001123882 (OMIM: 604054) 3-ketoacyl-CoA thiolas ( 331) 268 70.1 9e-12
XP_006713185 (OMIM: 604054) PREDICTED: 3-ketoacyl- ( 364) 268 70.1 9.8e-12
NP_001268442 (OMIM: 143450,609015) trifunctional e ( 452) 197 53.9 8.9e-07
NP_001268441 (OMIM: 143450,609015) trifunctional e ( 459) 197 53.9 9.1e-07
NP_000174 (OMIM: 143450,609015) trifunctional enzy ( 474) 197 53.9 9.3e-07
XP_011531105 (OMIM: 143450,609015) PREDICTED: trif ( 474) 197 53.9 9.3e-07
XP_016859428 (OMIM: 143450,609015) PREDICTED: trif ( 481) 175 48.9 3.1e-05
XP_005271160 (OMIM: 184755,613724) PREDICTED: non- ( 463) 167 47.1 0.0001
NP_002970 (OMIM: 184755,613724) non-specific lipid ( 547) 167 47.1 0.00012
NP_001317516 (OMIM: 184755,613724) non-specific li ( 366) 147 42.5 0.002
XP_011540237 (OMIM: 184755,613724) PREDICTED: non- ( 399) 147 42.5 0.0022
>>NP_006102 (OMIM: 604770) 3-ketoacyl-CoA thiolase, mito (397 aa)
initn: 2580 init1: 2580 opt: 2580 Z-score: 3182.7 bits: 597.7 E(85289): 1.5e-170
Smith-Waterman score: 2580; 100.0% identity (100.0% similar) in 397 aa overlap (1-397:1-397)
10 20 30 40 50 60
pF1KE1 MALLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MALLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 QSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 KYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 KDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 SGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSR
310 320 330 340 350 360
370 380 390
pF1KE1 ITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQSTA
:::::::::::::::::::::::::::::::::::::
NP_006 ITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQSTA
370 380 390
>>NP_005882 (OMIM: 100678,614055) acetyl-CoA acetyltrans (397 aa)
initn: 1026 init1: 534 opt: 1004 Z-score: 1238.9 bits: 238.1 E(85289): 2.9e-62
Smith-Waterman score: 1004; 43.0% identity (72.1% similar) in 391 aa overlap (7-394:8-395)
10 20 30 40 50
pF1KE1 MALLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNV
: .:.: :: .:...: : . ::. . : .:. . :.:: :. ::.:.:
NP_005 MNAGSDPVVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 LQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGT
: .. . :.... .::: .:: . . .::::.... . : : . .. .:. ::
NP_005 LAAGCGQNPV-RQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGM
70 80 90 100 110
120 130 140 150 160 170
pF1KE1 ESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVS-LTDQHVQLPMAMTAENLAVKHKISREE
:.::.::. . .: :.:.: .. : ::. . ::: . :..::::.: : ..:::.
NP_005 ENMSKAPHLAY-LRTGVKIG-EMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSRED
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 CDKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPV
:: :. ::.: . :. ::.:. :..:. :.:.:: ...:: : ...: ..:: :
NP_005 QDKVAVLSQNRTENAQKAGHFDKEIVPVLVSTRKGLIEVKTDEFPRHGSNIEAMSKLKPY
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 FKKDGT--VTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGP
: ::: :: .::::. :::.::.. ... . :...:::::::.. : .::::::::
NP_005 FLTDGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGP
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE1 VPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGG
.:::. :. ::: ::.:.:. :.::::: :. . : :. :.:..:::::::::::.
NP_005 IPAIKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGA
300 310 320 330 340 350
360 370 380 390
pF1KE1 SGSRITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQSTA
:: :: . :.: :.: : . .:.. :::::.:::. .:
NP_005 SGCRILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQRE
360 370 380 390
>>NP_001290182 (OMIM: 100678,614055) acetyl-CoA acetyltr (426 aa)
initn: 981 init1: 534 opt: 969 Z-score: 1195.2 bits: 230.1 E(85289): 7.8e-60
Smith-Waterman score: 969; 42.7% identity (72.0% similar) in 379 aa overlap (19-394:49-424)
10 20 30 40
pF1KE1 MALLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSP
...: : . ::. . : .:. . :.:
NP_001 SLGRSGGRLSSPRLLRVVAPTLTFAQTSRCSFNGALAAVPVQDLGSTVIKEVLKRATVAP
20 30 40 50 60 70
50 60 70 80 90 100
pF1KE1 ETVDSVIMGNVLQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICV
: :. ::.:.:: .. . :.... .::: .:: . . .::::.... . : : .
NP_001 EDVSEVIFGHVLAAGCGQNPV-RQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGI
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE1 KEAEVVLCGGTESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVS-LTDQHVQLPMAMTAEN
.. .:. :: :.::.::. . .: :.:.: .. : ::. . ::: . :..::::
NP_001 GDSSIVVAGGMENMSKAPH-LAYLRTGVKIG-EMPLTDSILCDGLTDAFHNCHMGITAEN
140 150 160 170 180 190
170 180 190 200 210 220
pF1KE1 LAVKHKISREECDKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQT
.: : ..:::. :: :. ::.: . :. ::.:. :..:. :.:.:: ...:: : .
NP_001 VAKKWQVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLVSTRKGLIEVKTDEFPRHGS
200 210 220 230 240 250
230 240 250 260 270 280
pF1KE1 TLEQLQKLPPVFKKDGT--VTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVS
..: ..:: : : ::: :: .::::. :::.::.. ... . :...:::::::..
NP_001 NIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQV
260 270 280 290 300 310
290 300 310 320 330 340
pF1KE1 GCDPSIMGIGPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNG
: .::::::::.:::. :. ::: ::.:.:. :.::::: :. . : :. :.:..:
NP_001 GVEPSIMGIGPIPAIKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEG
320 330 340 350 360 370
350 360 370 380 390
pF1KE1 GAIALGHPLGGSGSRITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQSTA
::::::::::.:: :: . :.: :.: : . .:.. :::::.:::. .:
NP_001 GAIALGHPLGASGCRILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQRE
380 390 400 410 420
>>NP_000010 (OMIM: 203750,607809) acetyl-CoA acetyltrans (427 aa)
initn: 657 init1: 401 opt: 876 Z-score: 1080.5 bits: 208.9 E(85289): 1.9e-53
Smith-Waterman score: 876; 42.0% identity (70.6% similar) in 395 aa overlap (4-394:39-425)
10 20 30
pF1KE1 MALLRGVFVVAAKRTPFGAYGGLLKDFTATDLS
:. : .:.: :::.:.. : :. . :: :.
NP_000 RSGARSRSPLLRRLVQEIRYVERSYVSKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLG
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE1 EFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARHVGLRVGIPKETPALTINRLCG
.: ..:. . . : : . ::::::.. .. .:.. : .:.: :: :::..:.
NP_000 SIAIQGAIEKAGIPKEEVKEAYMGNVLQGG-EGQAPTRQAVLGAGLPISTPCTTINKVCA
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE1 SGFQSIVNGCQEICVKEAEVVLCGGTESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVS--
::...:. . : . . .:.. :: ::::..:: : : : .: :. .:::: : :.
NP_000 SGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPY-VMN-RGSTPYGG-VKLED-LIVKDG
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE1 LTDQHVQLPMAMTAENLAVKHKISREECDKYALQSQQRWKAANDAGYFNDEMAPIEVKTK
::: . .. :. ::: : : .:.:.: : ::..: : ::: .:: :..:. :. : :
NP_000 LTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTV-TV
190 200 210 220 230 240
220 230 240 250 260
pF1KE1 KGKQTMQVDEHAR-PQTTLEQLQKLPPVFKKD-GTVTAGNASGVADGAGAVIIASEDAVK
::. . : : . .. . .. :: ::.:. :::::.::: . :::.:... . ::.:
NP_000 KGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVLMTADAAK
250 260 270 280 290 300
270 280 290 300 310 320
pF1KE1 KHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLA
. : :::::::.. .. .: . :.:: : : .:: .::. .:. . ::::::. ::
NP_000 RLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSLVVLA
310 320 330 340 350 360
330 340 350 360 370 380
pF1KE1 VERSLDLDISKTNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGKYAVGSACIGGGQGI
. :..: .:.:.::::..::::.: ::.::..::.: :.. :.:...: : ::: .
NP_000 NIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQ--GEYGLASICNGGGGAS
370 380 390 400 410 420
390
pF1KE1 AVIIQSTA
:..::
NP_000 AMLIQKL
>>NP_001598 (OMIM: 604054) 3-ketoacyl-CoA thiolase, pero (424 aa)
initn: 774 init1: 477 opt: 805 Z-score: 993.0 bits: 192.7 E(85289): 1.4e-48
Smith-Waterman score: 805; 39.2% identity (65.6% similar) in 395 aa overlap (7-394:38-420)
10 20 30
pF1KE1 MALLRGVFVVAAKRTPFGAYG-GLLKDFTATDLSEF
: :: ..:: . : : .:: : .:
NP_001 LGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSA
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE1 AAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSG
. :.:. .. :: . .. .::::: .. :: .:: . . ::. .: :.:: :.::
NP_001 VMTAVLKDVNLRPEQLGDICVGNVLQPGAGAI-MARIAQFLSDIPETVPLSTVNRQCSSG
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE1 FQSIVNGCQEICVKEAEVVLCGGTESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQ
.:.... : .. . :.:::: : :. .. . : . .
NP_001 LQAVASIAGGIRNGSYDIGMACGVESMSLADR-----------GNPGNITSRLMEKEKAR
130 140 150 160 170
160 170 180 190 200 210
pF1KE1 HVQLPMAMTAENLAVKHKISREECDKYALQSQQRWKAANDAGYFNDEMAPIE--VKTKKG
.::..:.::.: . ::::. : .:: :::. :.. : :. :..:. :. ::
NP_001 DCLIPMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKG
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE1 -KQTMQV--DEHARPQTTLEQLQKLPPVFKKDGTVTAGNASGVADGAGAVIIASEDAVKK
:... : :: ::.::.: : :: :.:::::..::::.: :.:::.:...: .. ...
NP_001 TKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEE
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE1 HNFTPLARIVGYFVSGCDPSIMGIGPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAV
.. :. . .: : : :.::::::. :: ::.::::...:.:. :.::::: :
NP_001 LGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYC
300 310 320 330 340 350
340 350 360 370 380
pF1KE1 ERSLDLDISKTNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGK-YAVGSACIGGGQGI
..: : :.: :::.::::::: .:.: . :..::.::: . :.: : ::: :.:
NP_001 VEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGA
360 370 380 390 400 410
390
pF1KE1 AVIIQSTA
:....
NP_001 AAVFEYPGN
420
>>XP_016873170 (OMIM: 203750,607809) PREDICTED: acetyl-C (337 aa)
initn: 566 init1: 401 opt: 785 Z-score: 969.9 bits: 188.1 E(85289): 2.8e-47
Smith-Waterman score: 785; 43.4% identity (71.7% similar) in 343 aa overlap (56-394:1-335)
30 40 50 60 70 80
pF1KE1 DFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARHVGLRVGIPKETPA
::::::.. .. .:.. : .:.: ::
XP_016 MGNVLQGG-EGQAPTRQAVLGAGLPISTPC
10 20
90 100 110 120 130 140
pF1KE1 LTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAPYCVRNVRFGTKLGSDIKLE
:::..:.::...:. . : . . .:.. :: ::::..:: : : : .: :. .:::
XP_016 TTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPY-VMN-RGSTPYGG-VKLE
30 40 50 60 70 80
150 160 170 180 190 200
pF1KE1 DSLWVS--LTDQHVQLPMAMTAENLAVKHKISREECDKYALQSQQRWKAANDAGYFNDEM
: : :. ::: . .. :. ::: : : .:.:.: : ::..: : ::: .:: :..:.
XP_016 D-LIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEV
90 100 110 120 130 140
210 220 230 240 250 260
pF1KE1 APIEVKTKKGKQTMQVDEHAR-PQTTLEQLQKLPPVFKKD-GTVTAGNASGVADGAGAVI
:. : : ::. . : : . .. . .. :: ::.:. :::::.::: . :::.:..
XP_016 IPVTV-TVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALV
150 160 170 180 190 200
270 280 290 300 310 320
pF1KE1 IASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGALKKAGLSLKDMDLVEVNE
. . ::.:. : :::::::.. .. .: . :.:: : : .:: .::. .:. . ::::
XP_016 LMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNE
210 220 230 240 250 260
330 340 350 360 370 380
pF1KE1 AFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGKYAVGSA
::. :: . :..: .:.:.::::..::::.: ::.::..::.: :.. :.:...:
XP_016 AFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQ--GEYGLASI
270 280 290 300 310 320
390
pF1KE1 CIGGGQGIAVIIQSTA
: ::: . :..::
XP_016 CNGGGGASAMLIQKL
330
>>XP_006718898 (OMIM: 203750,607809) PREDICTED: acetyl-C (337 aa)
initn: 566 init1: 401 opt: 785 Z-score: 969.9 bits: 188.1 E(85289): 2.8e-47
Smith-Waterman score: 785; 43.4% identity (71.7% similar) in 343 aa overlap (56-394:1-335)
30 40 50 60 70 80
pF1KE1 DFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARHVGLRVGIPKETPA
::::::.. .. .:.. : .:.: ::
XP_006 MGNVLQGG-EGQAPTRQAVLGAGLPISTPC
10 20
90 100 110 120 130 140
pF1KE1 LTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAPYCVRNVRFGTKLGSDIKLE
:::..:.::...:. . : . . .:.. :: ::::..:: : : : .: :. .:::
XP_006 TTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPY-VMN-RGSTPYGG-VKLE
30 40 50 60 70 80
150 160 170 180 190 200
pF1KE1 DSLWVS--LTDQHVQLPMAMTAENLAVKHKISREECDKYALQSQQRWKAANDAGYFNDEM
: : :. ::: . .. :. ::: : : .:.:.: : ::..: : ::: .:: :..:.
XP_006 D-LIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEV
90 100 110 120 130 140
210 220 230 240 250 260
pF1KE1 APIEVKTKKGKQTMQVDEHAR-PQTTLEQLQKLPPVFKKD-GTVTAGNASGVADGAGAVI
:. : : ::. . : : . .. . .. :: ::.:. :::::.::: . :::.:..
XP_006 IPVTV-TVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALV
150 160 170 180 190 200
270 280 290 300 310 320
pF1KE1 IASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGALKKAGLSLKDMDLVEVNE
. . ::.:. : :::::::.. .. .: . :.:: : : .:: .::. .:. . ::::
XP_006 LMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNE
210 220 230 240 250 260
330 340 350 360 370 380
pF1KE1 AFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGKYAVGSA
::. :: . :..: .:.:.::::..::::.: ::.::..::.: :.. :.:...:
XP_006 AFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQ--GEYGLASI
270 280 290 300 310 320
390
pF1KE1 CIGGGQGIAVIIQSTA
: ::: . :..::
XP_006 CNGGGGASAMLIQKL
330
>>XP_016873172 (OMIM: 203750,607809) PREDICTED: acetyl-C (301 aa)
initn: 451 init1: 401 opt: 675 Z-score: 835.0 bits: 162.9 E(85289): 9.1e-40
Smith-Waterman score: 675; 44.9% identity (72.1% similar) in 287 aa overlap (112-394:20-299)
90 100 110 120 130 140
pF1KE1 ETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAPYCVRNVRFGTKLGSD
.:.. :: ::::..:: : : : .: :.
XP_016 MFYKEVKDKLLQGRQYWVQDVMVAGGMESMSNVPY-VMN-RGSTPYGG-
10 20 30 40
150 160 170 180 190
pF1KE1 IKLEDSLWVS--LTDQHVQLPMAMTAENLAVKHKISREECDKYALQSQQRWKAANDAGYF
.:::: : :. ::: . .. :. ::: : : .:.:.: : ::..: : ::: .:: :
XP_016 VKLED-LIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKF
50 60 70 80 90 100
200 210 220 230 240 250
pF1KE1 NDEMAPIEVKTKKGKQTMQVDEHAR-PQTTLEQLQKLPPVFKKD-GTVTAGNASGVADGA
..:. :. : : ::. . : : . .. . .. :: ::.:. :::::.::: . :::
XP_016 GNEVIPVTV-TVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGA
110 120 130 140 150 160
260 270 280 290 300 310
pF1KE1 GAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGALKKAGLSLKDMDLV
.:... . ::.:. : :::::::.. .. .: . :.:: : : .:: .::. .:. .
XP_016 AALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMW
170 180 190 200 210 220
320 330 340 350 360 370
pF1KE1 EVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGKYA
::::::. :: . :..: .:.:.::::..::::.: ::.::..::.: :.. :.:.
XP_016 EVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQ--GEYG
230 240 250 260 270 280
380 390
pF1KE1 VGSACIGGGQGIAVIIQSTA
..: : ::: . :..::
XP_016 LASICNGGGGASAMLIQKL
290 300
>>XP_016873171 (OMIM: 203750,607809) PREDICTED: acetyl-C (301 aa)
initn: 451 init1: 401 opt: 675 Z-score: 835.0 bits: 162.9 E(85289): 9.1e-40
Smith-Waterman score: 675; 44.9% identity (72.1% similar) in 287 aa overlap (112-394:20-299)
90 100 110 120 130 140
pF1KE1 ETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAPYCVRNVRFGTKLGSD
.:.. :: ::::..:: : : : .: :.
XP_016 MFYKEVKDKLLQGRQYWVQDVMVAGGMESMSNVPY-VMN-RGSTPYGG-
10 20 30 40
150 160 170 180 190
pF1KE1 IKLEDSLWVS--LTDQHVQLPMAMTAENLAVKHKISREECDKYALQSQQRWKAANDAGYF
.:::: : :. ::: . .. :. ::: : : .:.:.: : ::..: : ::: .:: :
XP_016 VKLED-LIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKF
50 60 70 80 90 100
200 210 220 230 240 250
pF1KE1 NDEMAPIEVKTKKGKQTMQVDEHAR-PQTTLEQLQKLPPVFKKD-GTVTAGNASGVADGA
..:. :. : : ::. . : : . .. . .. :: ::.:. :::::.::: . :::
XP_016 GNEVIPVTV-TVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGA
110 120 130 140 150 160
260 270 280 290 300 310
pF1KE1 GAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGALKKAGLSLKDMDLV
.:... . ::.:. : :::::::.. .. .: . :.:: : : .:: .::. .:. .
XP_016 AALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMW
170 180 190 200 210 220
320 330 340 350 360 370
pF1KE1 EVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGKYA
::::::. :: . :..: .:.:.::::..::::.: ::.::..::.: :.. :.:.
XP_016 EVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQ--GEYG
230 240 250 260 270 280
380 390
pF1KE1 VGSACIGGGQGIAVIIQSTA
..: : ::: . :..::
XP_016 LASICNGGGGASAMLIQKL
290 300
>>XP_006713186 (OMIM: 604054) PREDICTED: 3-ketoacyl-CoA (272 aa)
initn: 621 init1: 477 opt: 656 Z-score: 812.2 bits: 158.6 E(85289): 1.7e-38
Smith-Waterman score: 656; 46.3% identity (73.6% similar) in 242 aa overlap (159-394:27-268)
130 140 150 160 170 180
pF1KE1 VRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYALQSQQ
.::..:.::.: . ::::. : .:: :::
XP_006 MSLADRGNPGNITSRLMEKEKARDCLIPMGITSENVAERFGISREKQDTFALASQQ
10 20 30 40 50
190 200 210 220 230 240
pF1KE1 RWKAANDAGYFNDEMAPIE--VKTKKG-KQTMQV--DEHARPQTTLEQLQKLPPVFKKDG
. :.. : :. :..:. :. :: :... : :: ::.::.: : :: :.:::::
XP_006 KAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDG
60 70 80 90 100 110
250 260 270 280 290 300
pF1KE1 TVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGA
..::::.: :.:::.:...: .. ... .. :. . .: : : :.::::::. :: :
XP_006 STTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVA
120 130 140 150 160 170
310 320 330 340 350 360
pF1KE1 LKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRITA
:.::::...:.:. :.::::: : ..: : :.: :::.::::::: .:.: .
XP_006 LQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQVI
180 190 200 210 220 230
370 380 390
pF1KE1 HLVHELRRRGGK-YAVGSACIGGGQGIAVIIQSTA
:..::.::: . :.: : ::: :.: :....
XP_006 TLLNELKRRGKRAYGVVSMCIGTGMGAAAVFEYPGN
240 250 260 270
397 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 07:47:27 2016 done: Sat Nov 5 07:47:29 2016
Total Scan time: 8.640 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]