Result of FASTA (omim) for
pF1KE1019
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1019, 663 aa
1>>>pF1KE1019 663 - 663 aa - 663 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.2111+/-0.000502; mu= 10.5264+/- 0.031
mean_var=125.0810+/-24.703, 0's: 0 Z-trim(112.4): 393 B-trim: 0 in 0/52
Lambda= 0.114678
statistics sampled from 20847 (21269) to 20847 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.604), E-opt: 0.2 (0.249), width: 16
Scan time: 10.650
The best scores are: opt bits E(85289)
NP_277050 (OMIM: 613351) rho GTPase-activating pro ( 663) 4251 715.4 1.7e-205
XP_005267269 (OMIM: 613351) PREDICTED: rho GTPase- ( 713) 4014 676.2 1.1e-193
XP_005267270 (OMIM: 613351) PREDICTED: rho GTPase- ( 585) 3660 617.6 4.1e-176
XP_016866983 (OMIM: 613351) PREDICTED: rho GTPase- ( 635) 3423 578.4 2.8e-164
NP_001010000 (OMIM: 610592) rho GTPase-activating ( 570) 1112 196.0 3.2e-49
XP_005258201 (OMIM: 610592) PREDICTED: rho GTPase- ( 747) 1112 196.1 3.9e-49
XP_005258202 (OMIM: 610592) PREDICTED: rho GTPase- ( 740) 1109 195.6 5.5e-49
XP_005258203 (OMIM: 610592) PREDICTED: rho GTPase- ( 721) 380 75.0 1.1e-12
NP_443083 (OMIM: 609866) stAR-related lipid transf ( 995) 347 69.6 6.3e-11
NP_001230405 (OMIM: 609866) stAR-related lipid tra (1078) 347 69.6 6.7e-11
XP_011533601 (OMIM: 609866) PREDICTED: stAR-relate (1078) 347 69.6 6.7e-11
XP_016876324 (OMIM: 609866) PREDICTED: stAR-relate (1078) 347 69.6 6.7e-11
XP_016876323 (OMIM: 609866) PREDICTED: stAR-relate (1098) 347 69.6 6.8e-11
NP_821075 (OMIM: 609866) stAR-related lipid transf (1105) 347 69.6 6.9e-11
NP_821074 (OMIM: 609866) stAR-related lipid transf (1113) 347 69.6 6.9e-11
XP_016868441 (OMIM: 114500,604258) PREDICTED: rho (1017) 338 68.1 1.8e-10
NP_001157743 (OMIM: 114500,604258) rho GTPase-acti (1017) 338 68.1 1.8e-10
NP_006085 (OMIM: 114500,604258) rho GTPase-activat (1091) 338 68.1 1.9e-10
NP_001303597 (OMIM: 114500,604258) rho GTPase-acti (1125) 338 68.1 2e-10
XP_016868440 (OMIM: 114500,604258) PREDICTED: rho (1528) 338 68.2 2.5e-10
XP_005273431 (OMIM: 114500,604258) PREDICTED: rho (1528) 338 68.2 2.5e-10
NP_872584 (OMIM: 114500,604258) rho GTPase-activat (1528) 338 68.2 2.5e-10
NP_954976 (OMIM: 610591) rho GTPase-activating pro ( 548) 309 63.2 3e-09
XP_011522776 (OMIM: 610591) PREDICTED: rho GTPase- ( 581) 309 63.2 3.1e-09
XP_005257185 (OMIM: 610591) PREDICTED: rho GTPase- ( 667) 309 63.2 3.5e-09
XP_016879801 (OMIM: 610591) PREDICTED: rho GTPase- ( 689) 309 63.2 3.6e-09
XP_011522774 (OMIM: 610591) PREDICTED: rho GTPase- ( 722) 309 63.2 3.8e-09
XP_011530602 (OMIM: 610586) PREDICTED: rho GTPase- ( 653) 308 63.0 3.9e-09
NP_001036134 (OMIM: 610586) rho GTPase-activating ( 653) 308 63.0 3.9e-09
NP_112595 (OMIM: 610586) rho GTPase-activating pro ( 655) 308 63.0 3.9e-09
NP_001274734 (OMIM: 610586) rho GTPase-activating ( 663) 308 63.0 3.9e-09
XP_011538307 (OMIM: 610585) PREDICTED: rho GTPase- ( 624) 307 62.9 4.2e-09
XP_005270071 (OMIM: 610585) PREDICTED: rho GTPase- ( 624) 307 62.9 4.2e-09
XP_011538309 (OMIM: 610585) PREDICTED: rho GTPase- ( 637) 307 62.9 4.3e-09
NP_001020787 (OMIM: 610586) rho GTPase-activating ( 748) 308 63.1 4.3e-09
XP_011522773 (OMIM: 610591) PREDICTED: rho GTPase- ( 865) 309 63.3 4.4e-09
XP_006721810 (OMIM: 610591) PREDICTED: rho GTPase- ( 867) 309 63.3 4.4e-09
NP_001269219 (OMIM: 610591) rho GTPase-activating ( 889) 309 63.3 4.5e-09
XP_006721808 (OMIM: 610591) PREDICTED: rho GTPase- ( 889) 309 63.3 4.5e-09
XP_011522771 (OMIM: 610591) PREDICTED: rho GTPase- ( 900) 309 63.3 4.5e-09
XP_016879800 (OMIM: 610591) PREDICTED: rho GTPase- ( 922) 309 63.3 4.6e-09
XP_011522770 (OMIM: 610591) PREDICTED: rho GTPase- ( 922) 309 63.3 4.6e-09
NP_001242953 (OMIM: 610585) rho GTPase-activating ( 714) 307 62.9 4.7e-09
XP_011538305 (OMIM: 610585) PREDICTED: rho GTPase- ( 720) 307 62.9 4.7e-09
XP_011538304 (OMIM: 610585) PREDICTED: rho GTPase- ( 720) 307 62.9 4.7e-09
XP_011538314 (OMIM: 610585) PREDICTED: rho GTPase- ( 552) 305 62.5 4.8e-09
XP_016871960 (OMIM: 610585) PREDICTED: rho GTPase- ( 552) 305 62.5 4.8e-09
XP_016871961 (OMIM: 610585) PREDICTED: rho GTPase- ( 552) 305 62.5 4.8e-09
XP_011538313 (OMIM: 610585) PREDICTED: rho GTPase- ( 565) 305 62.5 4.9e-09
NP_001242955 (OMIM: 610585) rho GTPase-activating ( 608) 305 62.5 5.2e-09
>>NP_277050 (OMIM: 613351) rho GTPase-activating protein (663 aa)
initn: 4251 init1: 4251 opt: 4251 Z-score: 3810.5 bits: 715.4 E(85289): 1.7e-205
Smith-Waterman score: 4251; 99.8% identity (100.0% similar) in 663 aa overlap (1-663:1-663)
10 20 30 40 50 60
pF1KE1 MSWLSSSQGVVLTAYHPSGKDQAVGNSHAKAGEEATSSRRYGQYTMNQESTTIKVMEKPP
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
NP_277 MSWLSSSQGVVLTAYHPSGKDQTVGNSHAKAGEEATSSRRYGQYTMNQESTTIKVMEKPP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FDRSISQDSLDELSMEDYWIELENIKKSSENSQEDQEVVVVKEPDEGELEEEWLKEAGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 FDRSISQDSLDELSMEDYWIELENIKKSSENSQEDQEVVVVKEPDEGELEEEWLKEAGLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 NLFGESAGDPQESIVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQIPDVRDIFAQQRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 NLFGESAGDPQESIVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQIPDVRDIFAQQRE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 SKETAPGGTESQSLRTNENKYQGRDDEASNLVGEEKLIPPEETPAPETDINLEVSFAEQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 SKETAPGGTESQSLRTNENKYQGRDDEASNLVGEEKLIPPEETPAPETDINLEVSFAEQA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 LNQKESSKEKIQKSKGDDATLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 LNQKESSKEKIQKSKGDDATLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALYD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 VLGIELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 VLGIELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLET
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 EGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 EGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 KAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 KAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 VMAPNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQKLLWTIPKFIVNQVRKQNTEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 VMAPNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQKLLWTIPKFIVNQVRKQNTEN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 HKKDKRAMKKLLKKMAYDREKYEKQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 HKKDKRAMKKLLKKMAYDREKYEKQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 ASDVLARFLSQESGVAQTLKKGEVFLYEIGGNIGERCLDDDTYMKDLYQLNPNAEWVIKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 ASDVLARFLSQESGVAQTLKKGEVFLYEIGGNIGERCLDDDTYMKDLYQLNPNAEWVIKS
610 620 630 640 650 660
pF1KE1 KPL
:::
NP_277 KPL
>>XP_005267269 (OMIM: 613351) PREDICTED: rho GTPase-acti (713 aa)
initn: 4012 init1: 4012 opt: 4014 Z-score: 3598.1 bits: 676.2 E(85289): 1.1e-193
Smith-Waterman score: 4014; 95.2% identity (97.1% similar) in 663 aa overlap (1-663:54-713)
10 20 30
pF1KE1 MSWLSSSQGVVLTAYHPSGKDQAVGNSHAK
..: . . :. .:. .. : : :
XP_005 CVDLGRGPWFQGLCVLCVCVCVATPGSDNSVTWETEDTDDCLVDLKPALNSCWVLN---K
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE1 AGEEATSSRRYGQYTMNQESTTIKVMEKPPFDRSISQDSLDELSMEDYWIELENIKKSSE
. . ..::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPGKLFAGRRYGQYTMNQESTTIKVMEKPPFDRSISQDSLDELSMEDYWIELENIKKSSE
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE1 NSQEDQEVVVVKEPDEGELEEEWLKEAGLSNLFGESAGDPQESIVFLSTLTRTQAAAVQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSQEDQEVVVVKEPDEGELEEEWLKEAGLSNLFGESAGDPQESIVFLSTLTRTQAAAVQK
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE1 RVETVSQTLRKKNKQYQIPDVRDIFAQQRESKETAPGGTESQSLRTNENKYQGRDDEASN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVETVSQTLRKKNKQYQIPDVRDIFAQQRESKETAPGGTESQSLRTNENKYQGRDDEASN
210 220 230 240 250 260
220 230 240 250 260 270
pF1KE1 LVGEEKLIPPEETPAPETDINLEVSFAEQALNQKESSKEKIQKSKGDDATLPSFRLPKDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVGEEKLIPPEETPAPETDINLEVSFAEQALNQKESSKEKIQKSKGDDATLPSFRLPKDK
270 280 290 300 310 320
280 290 300 310 320 330
pF1KE1 TGTTRIGDLAPQDMKKVCHLALIELTALYDVLGIELKQQKAVKIKTKDSGLFCVPLTALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TGTTRIGDLAPQDMKKVCHLALIELTALYDVLGIELKQQKAVKIKTKDSGLFCVPLTALL
330 340 350 360 370 380
340 350 360 370 380 390
pF1KE1 EQDQRKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EQDQRKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFN
390 400 410 420 430 440
400 410 420 430 440 450
pF1KE1 WESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDAN
450 460 470 480 490 500
460 470 480 490 500 510
pF1KE1 RDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTAN
510 520 530 540 550 560
520 530 540 550 560 570
pF1KE1 TMHLLIKYQKLLWTIPKFIVNQVRKQNTENHKKDKRAMKKLLKKMAYDREKYEKQDKSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TMHLLIKYQKLLWTIPKFIVNQVRKQNTENHKKDKRAMKKLLKKMAYDREKYEKQDKSTN
570 580 590 600 610 620
580 590 600 610 620 630
pF1KE1 DADVPQGVIRVQAPHLSKVSMAIQLTEELKASDVLARFLSQESGVAQTLKKGEVFLYEIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DADVPQGVIRVQAPHLSKVSMAIQLTEELKASDVLARFLSQESGVAQTLKKGEVFLYEIG
630 640 650 660 670 680
640 650 660
pF1KE1 GNIGERCLDDDTYMKDLYQLNPNAEWVIKSKPL
:::::::::::::::::::::::::::::::::
XP_005 GNIGERCLDDDTYMKDLYQLNPNAEWVIKSKPL
690 700 710
>>XP_005267270 (OMIM: 613351) PREDICTED: rho GTPase-acti (585 aa)
initn: 3655 init1: 3655 opt: 3660 Z-score: 3282.9 bits: 617.6 E(85289): 4.1e-176
Smith-Waterman score: 3660; 99.3% identity (99.5% similar) in 575 aa overlap (1-575:1-575)
10 20 30 40 50 60
pF1KE1 MSWLSSSQGVVLTAYHPSGKDQAVGNSHAKAGEEATSSRRYGQYTMNQESTTIKVMEKPP
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
XP_005 MSWLSSSQGVVLTAYHPSGKDQTVGNSHAKAGEEATSSRRYGQYTMNQESTTIKVMEKPP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FDRSISQDSLDELSMEDYWIELENIKKSSENSQEDQEVVVVKEPDEGELEEEWLKEAGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FDRSISQDSLDELSMEDYWIELENIKKSSENSQEDQEVVVVKEPDEGELEEEWLKEAGLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 NLFGESAGDPQESIVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQIPDVRDIFAQQRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLFGESAGDPQESIVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQIPDVRDIFAQQRE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 SKETAPGGTESQSLRTNENKYQGRDDEASNLVGEEKLIPPEETPAPETDINLEVSFAEQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKETAPGGTESQSLRTNENKYQGRDDEASNLVGEEKLIPPEETPAPETDINLEVSFAEQA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 LNQKESSKEKIQKSKGDDATLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNQKESSKEKIQKSKGDDATLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALYD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 VLGIELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLGIELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLET
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 EGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 KAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 VMAPNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQKLLWTIPKFIVNQVRKQNTEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VMAPNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQKLLWTIPKFIVNQVRKQNTEN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 HKKDKRAMKKLLKKMAYDREKYEKQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELK
::::::::::::::::::::::::::::::: :
XP_005 HKKDKRAMKKLLKKMAYDREKYEKQDKSTNDWGCPDSQERRSFFV
550 560 570 580
610 620 630 640 650 660
pF1KE1 ASDVLARFLSQESGVAQTLKKGEVFLYEIGGNIGERCLDDDTYMKDLYQLNPNAEWVIKS
>>XP_016866983 (OMIM: 613351) PREDICTED: rho GTPase-acti (635 aa)
initn: 3416 init1: 3416 opt: 3423 Z-score: 3070.4 bits: 578.4 E(85289): 2.8e-164
Smith-Waterman score: 3423; 93.9% identity (96.2% similar) in 575 aa overlap (1-575:54-625)
10 20 30
pF1KE1 MSWLSSSQGVVLTAYHPSGKDQAVGNSHAK
..: . . :. .:. .. : : :
XP_016 CVDLGRGPWFQGLCVLCVCVCVATPGSDNSVTWETEDTDDCLVDLKPALNSCWVLN---K
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE1 AGEEATSSRRYGQYTMNQESTTIKVMEKPPFDRSISQDSLDELSMEDYWIELENIKKSSE
. . ..::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPGKLFAGRRYGQYTMNQESTTIKVMEKPPFDRSISQDSLDELSMEDYWIELENIKKSSE
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE1 NSQEDQEVVVVKEPDEGELEEEWLKEAGLSNLFGESAGDPQESIVFLSTLTRTQAAAVQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSQEDQEVVVVKEPDEGELEEEWLKEAGLSNLFGESAGDPQESIVFLSTLTRTQAAAVQK
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE1 RVETVSQTLRKKNKQYQIPDVRDIFAQQRESKETAPGGTESQSLRTNENKYQGRDDEASN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVETVSQTLRKKNKQYQIPDVRDIFAQQRESKETAPGGTESQSLRTNENKYQGRDDEASN
210 220 230 240 250 260
220 230 240 250 260 270
pF1KE1 LVGEEKLIPPEETPAPETDINLEVSFAEQALNQKESSKEKIQKSKGDDATLPSFRLPKDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVGEEKLIPPEETPAPETDINLEVSFAEQALNQKESSKEKIQKSKGDDATLPSFRLPKDK
270 280 290 300 310 320
280 290 300 310 320 330
pF1KE1 TGTTRIGDLAPQDMKKVCHLALIELTALYDVLGIELKQQKAVKIKTKDSGLFCVPLTALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGTTRIGDLAPQDMKKVCHLALIELTALYDVLGIELKQQKAVKIKTKDSGLFCVPLTALL
330 340 350 360 370 380
340 350 360 370 380 390
pF1KE1 EQDQRKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQDQRKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFN
390 400 410 420 430 440
400 410 420 430 440 450
pF1KE1 WESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDAN
450 460 470 480 490 500
460 470 480 490 500 510
pF1KE1 RDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTAN
510 520 530 540 550 560
520 530 540 550 560 570
pF1KE1 TMHLLIKYQKLLWTIPKFIVNQVRKQNTENHKKDKRAMKKLLKKMAYDREKYEKQDKSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TMHLLIKYQKLLWTIPKFIVNQVRKQNTENHKKDKRAMKKLLKKMAYDREKYEKQDKSTN
570 580 590 600 610 620
580 590 600 610 620 630
pF1KE1 DADVPQGVIRVQAPHLSKVSMAIQLTEELKASDVLARFLSQESGVAQTLKKGEVFLYEIG
: :
XP_016 DWGCPDSQERRSFFV
630
>>NP_001010000 (OMIM: 610592) rho GTPase-activating prot (570 aa)
initn: 1238 init1: 555 opt: 1112 Z-score: 1004.8 bits: 196.0 E(85289): 3.2e-49
Smith-Waterman score: 1291; 44.7% identity (76.5% similar) in 459 aa overlap (215-661:117-567)
190 200 210 220 230 240
pF1KE1 APGGTESQSLRTNENKYQGRDDEASNLVGEEKLIPPEETPAPETDINLEVSFAEQALNQK
:: :::: : : ...:::..:.. .
NP_001 ETIPVLPVHSNGSPEPGQPVQNAISDDDFLEKNIPPE---AEE--LSFEVSYSEMVTEAL
90 100 110 120 130 140
250 260 270 280 290 300
pF1KE1 ESSKEKIQKSKGDDATLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALYDVLGI
. .: : .. : .: .: .: . : . : :. :::. .::::. ::.::::::..:..::
NP_001 KRNKLKKSEIKKEDYVLTKFNVQKTRFGLTEAGDLSAEDMKKIRHLSLIELTAFFDAFGI
150 160 170 180 190 200
310 320 330 340 350 360
pF1KE1 ELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGLL
.::..:. :.: .:.:.: ::::.::. :..: ::...::..::.. ..:: :::.::..
NP_001 QLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIF
210 220 230 240 250 260
370 380 390 400 410 420
pF1KE1 RIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQ
:. : . ..:. .::.::: :.:... ...:: .:: :.:::: :. :::. ::
NP_001 RLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFI
270 280 290 300 310 320
430 440 450 460 470 480
pF1KE1 AVQNL-PTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMA
.... : : :.:::.:.:. :::::::. .::. :...:: :. ::.:.. :.. :::
NP_001 SLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKVIANESKNRMSLWNISTVMA
330 340 350 360 370 380
490 500 510 520 530 540
pF1KE1 PNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQKLLWTIPKFIVNQVRKQNTENH--
::::. .. : :. .:...: .:. ..:..::::.:: .:.:...:::..: .
NP_001 PNLFFSRS---KHSDYEELLLANTAAHIIRLMLKYQKILWKVPSFLITQVRRMNEATMLL
390 400 410 420 430
550 560 570 580 590
pF1KE1 KKDKRAMKKLLKKMAYDREK--------YEKQDKSTNDADVPQGVIRVQAPHLSKVSMAI
::. ...:::.. . .:: .:. .. .:::.:::::.:: ::::::::
NP_001 KKQLPSVRKLLRRKTLERETASPKTSKVLQKSPSARRMSDVPEGVIRVHAPLLSKVSMAI
440 450 460 470 480 490
600 610 620 630 640 650
pF1KE1 QLTEELKASDVLARFLSQES-GVAQTLKKGEVFLYEIGGNIGERCLDDDTYMKDLYQLNP
::... ::.:.::.: ..: : .. .: . ::::::::::.::: :.:. :.:..::
NP_001 QLNNQTKAKDILAKFQYENSHGSSECIKIQNQRLYEIGGNIGEHCLDPDAYILDVYRINP
500 510 520 530 540 550
660
pF1KE1 NAEWVIKSKPL
.:::::: .
NP_001 QAEWVIKPQQSS
560 570
>>XP_005258201 (OMIM: 610592) PREDICTED: rho GTPase-acti (747 aa)
initn: 1431 init1: 555 opt: 1112 Z-score: 1003.0 bits: 196.1 E(85289): 3.9e-49
Smith-Waterman score: 1564; 40.3% identity (68.3% similar) in 704 aa overlap (27-661:54-744)
10 20 30 40 50
pF1KE1 MSWLSSSQGVVLTAYHPSGKDQAVGNSHAKAGEEATSSRRYGQYTMNQESTTIKVM
:: . . :: ... ...:: .
XP_005 SGGVVLTAYHSYARAQPPNAESRCAPRAAASHPLSRKSIPRCRRINRM-LSNES-----L
30 40 50 60 70
60 70 80 90 100 110
pF1KE1 EKPPFDRSISQDSLDELSMEDYWIELENIKKSSENSQEDQEVVVVKEPDEGELEEEWLKE
. : :.:: :. :.: ::::.: :.:.:: :: ..::. . : :::::: :::..
XP_005 HPPAFSRSNSEASVDSASMEDFWREIESIKDSSMGGQEEPPPAEVTPVDEGELEAEWLQD
80 90 100 110 120 130
120 130 140 150 160 170
pF1KE1 AGLSNLFGESAGDPQES-IVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQIPDVRDIF
.:::.:. .:: .:. ..::::::::::::::: .: .::.:::.:: .: ::::::
XP_005 VGLSTLI---SGDEEEDGKALLSTLTRTQAAAVQKRYHTYTQTMRKKDKQ-SIRDVRDIF
140 150 160 170 180 190
180 190 200
pF1KE1 AQQRESKETAPGGTESQSLRTNENKYQGR---------DDEA------------------
. .. . . :. .: :.:.. : :: .
XP_005 GVSESPPRDTCGNHTNQLDGTKEERELPRVIKTSGSMPDDASLNSTTLSDASQDKEGSFA
200 210 220 230 240 250
210 220 230
pF1KE1 ---SNLVGEEKLIP---------PE-----------------ETPAPETDINLEVSFAEQ
:. :. . :: :: . : ....:::..:.
XP_005 VPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAISDDDFLEKNIPPEAEELSFEVSYSEM
260 270 280 290 300 310
240 250 260 270 280 290
pF1KE1 ALNQKESSKEKIQKSKGDDATLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALY
. . . .: : .. : .: .: .: . : . : :. :::. .::::. ::.::::::..
XP_005 VTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLTEAGDLSAEDMKKIRHLSLIELTAFF
320 330 340 350 360 370
300 310 320 330 340 350
pF1KE1 DVLGIELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLE
:..::.::..:. :.: .:.:.: ::::.::. :..: ::...::..::.. ..:: :::
XP_005 DAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLVLQKFFEKVEESGLE
380 390 400 410 420 430
360 370 380 390 400 410
pF1KE1 TEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEY
.::..:. : . ..:. .::.::: :.:... ...:: .:: :.:::: :. :::
XP_005 SEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVMLKAFFRELPTSLFPVEY
440 450 460 470 480 490
420 430 440 450 460 470
pF1KE1 LKAFQAVQNL-PTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNV
. :: .... : : :.:::.:.:. :::::::. .::. :...:: :. ::.:.. :.
XP_005 IPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKVIANESKNRMSLWNI
500 510 520 530 540 550
480 490 500 510 520 530
pF1KE1 AMVMAPNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQKLLWTIPKFIVNQVRKQNT
. :::::::. .. : :. .:...: .:. ..:..::::.:: .:.:...:::..:
XP_005 STVMAPNLFFSRS---KHSDYEELLLANTAAHIIRLMLKYQKILWKVPSFLITQVRRMNE
560 570 580 590 600 610
540 550 560 570 580
pF1KE1 ENH--KKDKRAMKKLLKKMAYDREK--------YEKQDKSTNDADVPQGVIRVQAPHLSK
. ::. ...:::.. . .:: .:. .. .:::.:::::.:: :::
XP_005 ATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQKSPSARRMSDVPEGVIRVHAPLLSK
620 630 640 650 660 670
590 600 610 620 630 640
pF1KE1 VSMAIQLTEELKASDVLARFLSQES-GVAQTLKKGEVFLYEIGGNIGERCLDDDTYMKDL
:::::::... ::.:.::.: ..: : .. .: . ::::::::::.::: :.:. :.
XP_005 VSMAIQLNNQTKAKDILAKFQYENSHGSSECIKIQNQRLYEIGGNIGEHCLDPDAYILDV
680 690 700 710 720 730
650 660
pF1KE1 YQLNPNAEWVIKSKPL
:..::.:::::: .
XP_005 YRINPQAEWVIKPQQSS
740
>>XP_005258202 (OMIM: 610592) PREDICTED: rho GTPase-acti (740 aa)
initn: 1256 init1: 555 opt: 1109 Z-score: 1000.4 bits: 195.6 E(85289): 5.5e-49
Smith-Waterman score: 1382; 39.4% identity (67.5% similar) in 650 aa overlap (27-608:54-690)
10 20 30 40 50
pF1KE1 MSWLSSSQGVVLTAYHPSGKDQAVGNSHAKAGEEATSSRRYGQYTMNQESTTIKVM
:: . . :: ... ...:: .
XP_005 SGGVVLTAYHSYARAQPPNAESRCAPRAAASHPLSRKSIPRCRRINRM-LSNES-----L
30 40 50 60 70
60 70 80 90 100 110
pF1KE1 EKPPFDRSISQDSLDELSMEDYWIELENIKKSSENSQEDQEVVVVKEPDEGELEEEWLKE
. : :.:: :. :.: ::::.: :.:.:: :: ..::. . : :::::: :::..
XP_005 HPPAFSRSNSEASVDSASMEDFWREIESIKDSSMGGQEEPPPAEVTPVDEGELEAEWLQD
80 90 100 110 120 130
120 130 140 150 160 170
pF1KE1 AGLSNLFGESAGDPQES-IVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQIPDVRDIF
.:::.:. .:: .:. ..::::::::::::::: .: .::.:::.:: .: ::::::
XP_005 VGLSTLI---SGDEEEDGKALLSTLTRTQAAAVQKRYHTYTQTMRKKDKQ-SIRDVRDIF
140 150 160 170 180 190
180 190 200
pF1KE1 AQQRESKETAPGGTESQSLRTNENKYQGR---------DDEA------------------
. .. . . :. .: :.:.. : :: .
XP_005 GVSESPPRDTCGNHTNQLDGTKEERELPRVIKTSGSMPDDASLNSTTLSDASQDKEGSFA
200 210 220 230 240 250
210 220 230
pF1KE1 ---SNLVGEEKLIP---------PE-----------------ETPAPETDINLEVSFAEQ
:. :. . :: :: . : ....:::..:.
XP_005 VPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAISDDDFLEKNIPPEAEELSFEVSYSEM
260 270 280 290 300 310
240 250 260 270 280 290
pF1KE1 ALNQKESSKEKIQKSKGDDATLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALY
. . . .: : .. : .: .: .: . : . : :. :::. .::::. ::.::::::..
XP_005 VTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLTEAGDLSAEDMKKIRHLSLIELTAFF
320 330 340 350 360 370
300 310 320 330 340 350
pF1KE1 DVLGIELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLE
:..::.::..:. :.: .:.:.: ::::.::. :..: ::...::..::.. ..:: :::
XP_005 DAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLVLQKFFEKVEESGLE
380 390 400 410 420 430
360 370 380 390 400 410
pF1KE1 TEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEY
.::..:. : . ..:. .::.::: :.:... ...:: .:: :.:::: :. :::
XP_005 SEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVMLKAFFRELPTSLFPVEY
440 450 460 470 480 490
420 430 440 450 460 470
pF1KE1 LKAFQAVQNL-PTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNV
. :: .... : : :.:::.:.:. :::::::. .::. :...:: :. ::.:.. :.
XP_005 IPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKVIANESKNRMSLWNI
500 510 520 530 540 550
480 490 500 510 520 530
pF1KE1 AMVMAPNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQKLLWTIPKFIVNQVRKQNT
. :::::::. .. : :. .:...: .:. ..:..::::.:: .:.:...:::..:
XP_005 STVMAPNLFFSRS---KHSDYEELLLANTAAHIIRLMLKYQKILWKVPSFLITQVRRMNE
560 570 580 590 600 610
540 550 560 570 580
pF1KE1 ENH--KKDKRAMKKLLKKMAYDREK--------YEKQDKSTNDADVPQGVIRVQAPHLSK
. ::. ...:::.. . .:: .:. .. .:::.:::::.:: :::
XP_005 ATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQKSPSARRMSDVPEGVIRVHAPLLSK
620 630 640 650 660 670
590 600 610 620 630 640
pF1KE1 VSMAIQLTEELKASDVLARFLSQESGVAQTLKKGEVFLYEIGGNIGERCLDDDTYMKDLY
:::::::... ::.:.::.:
XP_005 VSMAIQLNNQTKAKDILAKFQYENRILHWQRAALSFLNGKWVKKEREESTETNRSPKHVF
680 690 700 710 720 730
>>XP_005258203 (OMIM: 610592) PREDICTED: rho GTPase-acti (721 aa)
initn: 1339 init1: 330 opt: 380 Z-score: 348.8 bits: 75.0 E(85289): 1.1e-12
Smith-Waterman score: 1421; 39.1% identity (65.5% similar) in 704 aa overlap (27-661:54-718)
10 20 30 40 50
pF1KE1 MSWLSSSQGVVLTAYHPSGKDQAVGNSHAKAGEEATSSRRYGQYTMNQESTTIKVM
:: . . :: ... ...:: .
XP_005 SGGVVLTAYHSYARAQPPNAESRCAPRAAASHPLSRKSIPRCRRINRM-LSNES-----L
30 40 50 60 70
60 70 80 90 100 110
pF1KE1 EKPPFDRSISQDSLDELSMEDYWIELENIKKSSENSQEDQEVVVVKEPDEGELEEEWLKE
. : :.:: :. :.: ::::.: :.:.:: :: ..::. . : :::::: :::..
XP_005 HPPAFSRSNSEASVDSASMEDFWREIESIKDSSMGGQEEPPPAEVTPVDEGELEAEWLQD
80 90 100 110 120 130
120 130 140 150 160 170
pF1KE1 AGLSNLFGESAGDPQES-IVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQIPDVRDIF
.:::.:. .:: .:. ..::::::::::::::: .: .::.:::.:: .: ::::::
XP_005 VGLSTLI---SGDEEEDGKALLSTLTRTQAAAVQKRYHTYTQTMRKKDKQ-SIRDVRDIF
140 150 160 170 180 190
180 190 200
pF1KE1 AQQRESKETAPGGTESQSLRTNENKYQGR---------DDEA------------------
. .. . . :. .: :.:.. : :: .
XP_005 GVSESPPRDTCGNHTNQLDGTKEERELPRVIKTSGSMPDDASLNSTTLSDASQDKEGSFA
200 210 220 230 240 250
210 220 230
pF1KE1 ---SNLVGEEKLIP---------PE-----------------ETPAPETDINLEVSFAEQ
:. :. . :: :: . : ....:::..:.
XP_005 VPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAISDDDFLEKNIPPEAEELSFEVSYSEM
260 270 280 290 300 310
240 250 260 270 280 290
pF1KE1 ALNQKESSKEKIQKSKGDDATLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALY
. . . .: : .. : .: .: .: . : . : :. :::. .::::. ::.::::::..
XP_005 VTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLTEAGDLSAEDMKKIRHLSLIELTAFF
320 330 340 350 360 370
300 310 320 330 340 350
pF1KE1 DVLGIELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLE
:..::.::..:. :.: .:.:.: ::::.::. :..: ::...::..:: . :
XP_005 DAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLVLQK-----QYR---
380 390 400 410 420
360 370 380 390 400 410
pF1KE1 TEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEY
.::.::: :.:... ...:: .:: :.:::: :. :::
XP_005 ------------------EELDAKFNADKFKWDKMCHREAAVMLKAFFRELPTSLFPVEY
430 440 450 460
420 430 440 450 460 470
pF1KE1 LKAFQAVQNL-PTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNV
. :: .... : : :.:::.:.:. :::::::. .::. :...:: :. ::.:.. :.
XP_005 IPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKVIANESKNRMSLWNI
470 480 490 500 510 520
480 490 500 510 520 530
pF1KE1 AMVMAPNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQKLLWTIPKFIVNQVRKQNT
. :::::::. .. : :. .:...: .:. ..:..::::.:: .:.:...:::..:
XP_005 STVMAPNLFFSRS---KHSDYEELLLANTAAHIIRLMLKYQKILWKVPSFLITQVRRMNE
530 540 550 560 570 580
540 550 560 570 580
pF1KE1 ENH--KKDKRAMKKLLKKMAYDREK--------YEKQDKSTNDADVPQGVIRVQAPHLSK
. ::. ...:::.. . .:: .:. .. .:::.:::::.:: :::
XP_005 ATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQKSPSARRMSDVPEGVIRVHAPLLSK
590 600 610 620 630 640
590 600 610 620 630 640
pF1KE1 VSMAIQLTEELKASDVLARFLSQES-GVAQTLKKGEVFLYEIGGNIGERCLDDDTYMKDL
:::::::... ::.:.::.: ..: : .. .: . ::::::::::.::: :.:. :.
XP_005 VSMAIQLNNQTKAKDILAKFQYENSHGSSECIKIQNQRLYEIGGNIGEHCLDPDAYILDV
650 660 670 680 690 700
650 660
pF1KE1 YQLNPNAEWVIKSKPL
:..::.:::::: .
XP_005 YRINPQAEWVIKPQQSS
710 720
>>NP_443083 (OMIM: 609866) stAR-related lipid transfer p (995 aa)
initn: 300 init1: 266 opt: 347 Z-score: 317.2 bits: 69.6 E(85289): 6.3e-11
Smith-Waterman score: 366; 26.2% identity (60.8% similar) in 370 aa overlap (206-539:417-766)
180 190 200 210 220 230
pF1KE1 AQQRESKETAPGGTESQSLRTNENKYQGRDDEASNLVGEEKLIPPEETPAPETDINLEVS
: .: :.: . : .:.. .:.
NP_443 KDVLPELQTHDTLVGEPGLSTFPSPNQITLDFEGNSVSEGRTTP--------SDVERDVT
390 400 410 420 430
240 250 260 270 280
pF1KE1 FAEQALNQKESSKEKIQKSKGDDATL--PSFRL----------PKDKTGTTRIGDLAPQD
.::..: . ....: :.: :. :: :. .. .:.. . ..
NP_443 ----SLNESEPPGVRDRRDSGVGASLTRPNRRLRWNSFQLSHQPRPAPASPHISSQTASQ
440 450 460 470 480 490
290 300 310 320 330
pF1KE1 MKKVCHLALIELTALYDVLGIELKQ---------QKAVKIKT-KDSGLFCVPLTALLEQD
.. . ...:..:::... .. :. .: .:. ::...: ::: . .
NP_443 LSLLQRFSLLRLTAIMEKHSMSNKHGWTWSVPKFMKRMKVPDYKDKAVFGVPLIVHV---
500 510 520 530 540 550
340 350 360 370 380 390
pF1KE1 QRKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWES
:: :. .: .:. . .. :. ::.: :. ::. : .... .: :.. :.:.
NP_443 QR--TGQPLPQSIQQALRYLRSNCLDQVGLFRKSGVKSRIHAL-RQMNENFPENV-NYED
560 570 580 590 600
400 410 420 430 440 450
pF1KE1 VKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDANRDT
. .:.:...: :.:.::.::.. . ..: . . .:.:.:::.. ..:: : ::..
NP_443 QSAYDVADMVKQFFRDLPEPLFTNKLSETFLHIYQYVSKEQRLQAVQAAILLLADENREV
610 620 630 640 650 660
460 470 480 490 500
pF1KE1 LKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSE---QREFVMA-----
:..:: ::. :.. :.:.:: ::.:. .::.:: . : .:: :.... .
NP_443 LQTLLCFLNDVVNLVEENQMTPMNLAVCLAPSLFHLNLLKKESSPRVIQKKYATGKPDQK
670 680 690 700 710 720
510 520 530 540 550
pF1KE1 ------AGTANTMHLLIKYQKLLWTIPKFIVNQVRKQNTENHKKDKRAMKKLLKKMAYDR
:.. . :.... ..:. .:. .: : :.. .:
NP_443 DLNENLAAAQGLAHMIMECDRLF-EVPHELVAQSRNSYVEAEIHVPTLEELGTQLEESGA
730 740 750 760 770 780
560 570 580 590 600 610
pF1KE1 EKYEKQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELKASDVLARFLSQESGVAQTL
NP_443 TFHTYLNHLIQGLQKEAKEKFKGWVTCSSTDNTDLAFKKVGDGNPLKLWKASVEVEAPPS
790 800 810 820 830 840
>>NP_001230405 (OMIM: 609866) stAR-related lipid transfe (1078 aa)
initn: 266 init1: 266 opt: 347 Z-score: 316.7 bits: 69.6 E(85289): 6.7e-11
Smith-Waterman score: 366; 26.2% identity (60.8% similar) in 370 aa overlap (206-539:500-849)
180 190 200 210 220 230
pF1KE1 AQQRESKETAPGGTESQSLRTNENKYQGRDDEASNLVGEEKLIPPEETPAPETDINLEVS
: .: :.: . : .:.. .:.
NP_001 KDVLPELQTHDTLVGEPGLSTFPSPNQITLDFEGNSVSEGRTTP--------SDVERDVT
470 480 490 500 510 520
240 250 260 270 280
pF1KE1 FAEQALNQKESSKEKIQKSKGDDATL--PSFRL----------PKDKTGTTRIGDLAPQD
.::..: . ....: :.: :. :: :. .. .:.. . ..
NP_001 ----SLNESEPPGVRDRRDSGVGASLTRPNRRLRWNSFQLSHQPRPAPASPHISSQTASQ
530 540 550 560 570
290 300 310 320 330
pF1KE1 MKKVCHLALIELTALYDVLGIELKQ---------QKAVKIKT-KDSGLFCVPLTALLEQD
.. . ...:..:::... .. :. .: .:. ::...: ::: . .
NP_001 LSLLQRFSLLRLTAIMEKHSMSNKHGWTWSVPKFMKRMKVPDYKDKAVFGVPLIVHV---
580 590 600 610 620 630
340 350 360 370 380 390
pF1KE1 QRKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWES
:: :. .: .:. . .. :. ::.: :. ::. : .... .: :.. :.:.
NP_001 QR--TGQPLPQSIQQALRYLRSNCLDQVGLFRKSGVKSRIHAL-RQMNENFPENV-NYED
640 650 660 670 680 690
400 410 420 430 440 450
pF1KE1 VKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDANRDT
. .:.:...: :.:.::.::.. . ..: . . .:.:.:::.. ..:: : ::..
NP_001 QSAYDVADMVKQFFRDLPEPLFTNKLSETFLHIYQYVSKEQRLQAVQAAILLLADENREV
700 710 720 730 740 750
460 470 480 490 500
pF1KE1 LKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSE---QREFVMA-----
:..:: ::. :.. :.:.:: ::.:. .::.:: . : .:: :.... .
NP_001 LQTLLCFLNDVVNLVEENQMTPMNLAVCLAPSLFHLNLLKKESSPRVIQKKYATGKPDQK
760 770 780 790 800 810
510 520 530 540 550
pF1KE1 ------AGTANTMHLLIKYQKLLWTIPKFIVNQVRKQNTENHKKDKRAMKKLLKKMAYDR
:.. . :.... ..:. .:. .: : :.. .:
NP_001 DLNENLAAAQGLAHMIMECDRLF-EVPHELVAQSRNSYVEAEIHVPTLEELGTQLEESGA
820 830 840 850 860
560 570 580 590 600 610
pF1KE1 EKYEKQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELKASDVLARFLSQESGVAQTL
NP_001 TFHTYLNHLIQGLQKEAKEKFKGWVTCSSTDNTDLAFKKVGDGNPLKLWKASVEVEAPPS
870 880 890 900 910 920
663 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 07:25:17 2016 done: Sat Nov 5 07:25:18 2016
Total Scan time: 10.650 Total Display time: 0.160
Function used was FASTA [36.3.4 Apr, 2011]