Result of FASTA (omim) for
pF1KE1003
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1003, 153 aa
1>>>pF1KE1003 153 - 153 aa - 153 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.6952+/-0.000392; mu= 14.5529+/- 0.024
mean_var=57.9044+/-11.932, 0's: 0 Z-trim(112.1): 52 B-trim: 33 in 1/48
Lambda= 0.168546
statistics sampled from 20885 (20937) to 20885 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.618), E-opt: 0.2 (0.245), width: 16
Scan time: 4.400
The best scores are: opt bits E(85289)
NP_002362 (OMIM: 188860) myelin and lymphocyte pro ( 153) 1001 251.5 3.9e-67
NP_071883 (OMIM: 188860) myelin and lymphocyte pro ( 111) 591 151.7 3.1e-37
NP_071884 (OMIM: 188860) myelin and lymphocyte pro ( 97) 421 110.3 7.8e-25
NP_005425 (OMIM: 602022) MAL-like protein [Homo sa ( 153) 396 104.4 7.5e-23
XP_011510111 (OMIM: 602022) PREDICTED: MAL-like pr ( 149) 325 87.1 1.2e-17
NP_443118 (OMIM: 609684) protein MAL2 [Homo sapien ( 176) 293 79.4 2.9e-15
NP_849199 (OMIM: 607891) CKLF-like MARVEL transmem ( 173) 250 68.9 4e-12
NP_071885 (OMIM: 188860) myelin and lymphocyte pro ( 55) 220 61.3 2.6e-10
XP_016861268 (OMIM: 607891) PREDICTED: CKLF-like M ( 130) 213 59.8 1.6e-09
XP_011531718 (OMIM: 607891) PREDICTED: CKLF-like M ( 196) 214 60.2 1.9e-09
NP_057077 (OMIM: 600340) plasmolipin [Homo sapiens ( 182) 198 56.3 2.7e-08
NP_001277123 (OMIM: 609959) myeloid-associated dif ( 322) 179 51.8 1e-06
NP_001277118 (OMIM: 609959) myeloid-associated dif ( 322) 179 51.8 1e-06
NP_001277119 (OMIM: 609959) myeloid-associated dif ( 322) 179 51.8 1e-06
NP_001018656 (OMIM: 609959) myeloid-associated dif ( 322) 179 51.8 1e-06
NP_612382 (OMIM: 609959) myeloid-associated differ ( 322) 179 51.8 1e-06
NP_001277122 (OMIM: 609959) myeloid-associated dif ( 322) 179 51.8 1e-06
NP_001277120 (OMIM: 609959) myeloid-associated dif ( 322) 179 51.8 1e-06
NP_001277117 (OMIM: 609959) myeloid-associated dif ( 322) 179 51.8 1e-06
NP_001018657 (OMIM: 609959) myeloid-associated dif ( 322) 179 51.8 1e-06
NP_001277121 (OMIM: 609959) myeloid-associated dif ( 322) 179 51.8 1e-06
NP_001018654 (OMIM: 609959) myeloid-associated dif ( 322) 179 51.8 1e-06
NP_001018655 (OMIM: 609959) myeloid-associated dif ( 322) 179 51.8 1e-06
XP_016861269 (OMIM: 607891) PREDICTED: CKLF-like M ( 100) 158 46.4 1.4e-05
>>NP_002362 (OMIM: 188860) myelin and lymphocyte protein (153 aa)
initn: 1001 init1: 1001 opt: 1001 Z-score: 1326.2 bits: 251.5 E(85289): 3.9e-67
Smith-Waterman score: 1001; 100.0% identity (100.0% similar) in 153 aa overlap (1-153:1-153)
10 20 30 40 50 60
pF1KE1 MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFIFGGLVWILVASSLVPWPLVQGWVMFVSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFIFGGLVWILVASSLVPWPLVQGWVMFVSV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FCFVATTTLIILYIIGAHGGETSWVTLDAAYHCTAALFYLSASVLEALATITMQDGFTYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FCFVATTTLIILYIIGAHGGETSWVTLDAAYHCTAALFYLSASVLEALATITMQDGFTYR
70 80 90 100 110 120
130 140 150
pF1KE1 HYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS
:::::::::::::::::::::::::::::::::
NP_002 HYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS
130 140 150
>>NP_071883 (OMIM: 188860) myelin and lymphocyte protein (111 aa)
initn: 581 init1: 581 opt: 591 Z-score: 789.4 bits: 151.7 E(85289): 3.1e-37
Smith-Waterman score: 637; 72.5% identity (72.5% similar) in 153 aa overlap (1-153:1-111)
10 20 30 40 50 60
pF1KE1 MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFIFGGLVWILVASSLVPWPLVQGWVMFVSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFIFGGLVWILVASSLVPWPLVQGWVMFVSV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FCFVATTTLIILYIIGAHGGETSWVTLDAAYHCTAALFYLSASVLEALATITMQDGFTYR
:::::::::::::::::::::::::::
NP_071 FCFVATTTLIILYIIGAHGGETSWVTL---------------------------------
70 80
130 140 150
pF1KE1 HYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS
::::::::::::::::::::::::
NP_071 ---------VFSYIATLLYVVHAVFSLIRWKSS
90 100 110
>>NP_071884 (OMIM: 188860) myelin and lymphocyte protein (97 aa)
initn: 421 init1: 421 opt: 421 Z-score: 566.9 bits: 110.3 E(85289): 7.8e-25
Smith-Waterman score: 498; 63.4% identity (63.4% similar) in 153 aa overlap (1-153:1-97)
10 20 30 40 50 60
pF1KE1 MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFIFGGLVWILVASSLVPWPLVQGWVMFVSV
:::::::::::::::::::::::::::::::
NP_071 MAPAAATGGSTLPSGFSVFTTLPDLLFIFEF-----------------------------
10 20 30
70 80 90 100 110 120
pF1KE1 FCFVATTTLIILYIIGAHGGETSWVTLDAAYHCTAALFYLSASVLEALATITMQDGFTYR
:::::::::::::::::::::::::::::::::
NP_071 ---------------------------DAAYHCTAALFYLSASVLEALATITMQDGFTYR
40 50 60
130 140 150
pF1KE1 HYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS
:::::::::::::::::::::::::::::::::
NP_071 HYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS
70 80 90
>>NP_005425 (OMIM: 602022) MAL-like protein [Homo sapien (153 aa)
initn: 393 init1: 393 opt: 396 Z-score: 531.2 bits: 104.4 E(85289): 7.5e-23
Smith-Waterman score: 396; 42.8% identity (73.8% similar) in 145 aa overlap (3-147:7-150)
10 20 30 40 50
pF1KE1 MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFIFGGLVWILVASSLVPWPLVQGWVM
::.. . : .::: ..: :.: .:. :.::: ::: .::.. . .::.:::::
NP_005 MASPDPPATSYAPSDVPSGVALFLTIPFAFFLPELIFGFLVWTMVAATHIVYPLLQGWVM
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 FVSVFCFVATTTLIILYIIGAHGGETSWVTLDAAYHCTAALFYLSASVLEALATITMQDG
.::. :. . ... :..: . :: .::. :: :....:.::.::.. :::. .
NP_005 YVSLTSFLISLMFLLSYLFGFYKRFESWRVLDSLYHGTTGILYMSAAVLQVHATIVSEKL
70 80 90 100 110 120
120 130 140 150
pF1KE1 FTYRHYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS
. : :. : :: :..::::::..:: ::.
NP_005 LDPRIYYINSAASFFAFIATLLYILHA-FSIYYH
130 140 150
>>XP_011510111 (OMIM: 602022) PREDICTED: MAL-like protei (149 aa)
initn: 322 init1: 322 opt: 325 Z-score: 438.0 bits: 87.1 E(85289): 1.2e-17
Smith-Waterman score: 325; 43.6% identity (74.4% similar) in 117 aa overlap (31-147:31-146)
10 20 30 40 50 60
pF1KE1 MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFIFGGLVWILVASSLVPWPLVQGWVMFVSV
.::: ::: .::.. . .::.:::::.::.
XP_011 MEKLTEDSRKKKKGAGIFGKETRIQNTTKLLIFGFLVWTMVAATHIVYPLLQGWVMYVSL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FCFVATTTLIILYIIGAHGGETSWVTLDAAYHCTAALFYLSASVLEALATITMQDGFTYR
:. . ... :..: . :: .::. :: :....:.::.::.. :::. . . :
XP_011 TSFLISLMFLLSYLFGFYKRFESWRVLDSLYHGTTGILYMSAAVLQVHATIVSEKLLDPR
70 80 90 100 110 120
130 140 150
pF1KE1 HYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS
:. : :: :..::::::..:: ::.
XP_011 IYYINSAASFFAFIATLLYILHA-FSIYYH
130 140
>>NP_443118 (OMIM: 609684) protein MAL2 [Homo sapiens] (176 aa)
initn: 342 init1: 210 opt: 293 Z-score: 395.0 bits: 79.4 E(85289): 2.9e-15
Smith-Waterman score: 338; 40.1% identity (64.5% similar) in 152 aa overlap (11-151:24-175)
10 20 30 40
pF1KE1 MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFIFGGLVWILVASSLVP
:::.: ... : . .:..:::::::::::: ::
NP_443 MSAGGASVPPPPNPAVSFPPPRVTLPAGPDILRTYSGAFVCLEILFGGLVWILVASSNVP
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 WPLVQGWVMFVSVFCFVATTTLIILYIIGAHGG-ETSWVTLDAAYHCTAALFYLSASVLE
::.::::::::: : . .. ... : . ...: :: ::: :. .::..: .::
NP_443 LPLLQGWVMFVSVTAFFFSLLFLGMFLSGMVAQIDANWNFLDFAYHFTVFVFYFGAFLLE
70 80 90 100 110 120
110 120 130 140 150
pF1KE1 ALAT----------ITMQDGFTYRHYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS
: :: :: : .. .:. :.:: .:....: : ..: ::.
NP_443 AAATSLHDLHCNTTITGQPLLSDNQYNINVAASIFAFMTTACYGCSLGLALRRWRP
130 140 150 160 170
>>NP_849199 (OMIM: 607891) CKLF-like MARVEL transmembran (173 aa)
initn: 184 init1: 148 opt: 250 Z-score: 338.6 bits: 68.9 E(85289): 4e-12
Smith-Waterman score: 250; 30.2% identity (66.4% similar) in 149 aa overlap (6-152:24-169)
10 20 30 40
pF1KE1 MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFIFGGLVWILVA
.:..:.. . ::: .:.. :...: ::: :.:
NP_849 MEEPQRARSHTVTTTASSFAENFSTSSSSFAYDREFLRTLPGFLIVAEIVLGLLVWTLIA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 SSLVPWPLVQGWVMFVSVFCFVATTTLIILYIIGAHG--GETSWVTLDAAYHCTAALFYL
.. . ::::::.:: .: :. ..:.:: .. .. :.:. .. .: ..::
NP_849 GTEYFRVPAFGWVMFVAVFYWVLTVFFLIIYITMTYTRIPQVPWTTVGLCFNGSAFVLYL
70 80 90 100 110 120
110 120 130 140 150
pF1KE1 SASVLEALATITMQDGFTYRHYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS
::.:..: .. .:. .. . :. :....:. :. .. ::.: :.:
NP_849 SAAVVDASSVSPERDSHNFNSW---AASSFFAFLVTICYAGNTYFSFIAWRSRTIQ
130 140 150 160 170
>>NP_071885 (OMIM: 188860) myelin and lymphocyte protein (55 aa)
initn: 254 init1: 215 opt: 220 Z-score: 306.2 bits: 61.3 E(85289): 2.6e-10
Smith-Waterman score: 220; 69.2% identity (82.7% similar) in 52 aa overlap (1-48:1-52)
10 20 30 40 50
pF1KE1 MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFIFGGLVWILVAS----SLVPWPLVQGWVM
:::::::::::::::::::::::::::::::.:. .. .: . ::. :
NP_071 MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFVFSYIATLLYVVHAVFSLIRWKSS
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 FVSVFCFVATTTLIILYIIGAHGGETSWVTLDAAYHCTAALFYLSASVLEALATITMQDG
>>XP_016861268 (OMIM: 607891) PREDICTED: CKLF-like MARVE (130 aa)
initn: 152 init1: 116 opt: 213 Z-score: 291.7 bits: 59.8 E(85289): 1.6e-09
Smith-Waterman score: 213; 30.9% identity (66.7% similar) in 123 aa overlap (32-152:7-126)
10 20 30 40 50 60
pF1KE1 APAAATGGSTLPSGFSVFTTLPDLLFIFEFIFGGLVWILVASSLVPWPLVQGWVMFVSVF
..: ::: :.:.. . ::::::.::
XP_016 MFRRIQVLGLLVWTLIAGTEYFRVPAFGWVMFVAVF
10 20 30
70 80 90 100 110
pF1KE1 CFVATTTLIILYIIGAHG--GETSWVTLDAAYHCTAALFYLSASVLEALATITMQDGFTY
.: :. ..:.:: .. .. :.:. .. .: ..::::.:..: .. .:. ..
XP_016 YWVLTVFFLIIYITMTYTRIPQVPWTTVGLCFNGSAFVLYLSAAVVDASSVSPERDSHNF
40 50 60 70 80 90
120 130 140 150
pF1KE1 RHYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS
. :. :....:. :. .. ::.: :.:
XP_016 NSW---AASSFFAFLVTICYAGNTYFSFIAWRSRTIQ
100 110 120 130
>>XP_011531718 (OMIM: 607891) PREDICTED: CKLF-like MARVE (196 aa)
initn: 153 init1: 117 opt: 214 Z-score: 290.5 bits: 60.2 E(85289): 1.9e-09
Smith-Waterman score: 214; 30.6% identity (66.9% similar) in 124 aa overlap (31-152:72-192)
10 20 30 40 50 60
pF1KE1 MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFIFGGLVWILVASSLVPWPLVQGWVMFVSV
...: ::: :.:.. . ::::::.:
XP_011 GFLIVAEILISLPITDPLHRSALSTTARDILVLGLLVWTLIAGTEYFRVPAFGWVMFVAV
50 60 70 80 90 100
70 80 90 100 110
pF1KE1 FCFVATTTLIILYIIGAHG--GETSWVTLDAAYHCTAALFYLSASVLEALATITMQDGFT
: .: :. ..:.:: .. .. :.:. .. .: ..::::.:..: .. .:. .
XP_011 FYWVLTVFFLIIYITMTYTRIPQVPWTTVGLCFNGSAFVLYLSAAVVDASSVSPERDSHN
110 120 130 140 150 160
120 130 140 150
pF1KE1 YRHYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS
. . :. :....:. :. .. ::.: :.:
XP_011 FNSW---AASSFFAFLVTICYAGNTYFSFIAWRSRTIQ
170 180 190
153 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 13:20:56 2016 done: Sat Nov 5 13:20:57 2016
Total Scan time: 4.400 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]