Result of FASTA (omim) for
pF1KE0946
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0946, 367 aa
1>>>pF1KE0946 367 - 367 aa - 367 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.1156+/-0.000509; mu= 1.7135+/- 0.031
mean_var=564.9827+/-126.344, 0's: 0 Z-trim(119.4): 1634 B-trim: 0 in 0/59
Lambda= 0.053958
statistics sampled from 31043 (33332) to 31043 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.737), E-opt: 0.2 (0.391), width: 16
Scan time: 9.200
The best scores are: opt bits E(85289)
NP_114417 (OMIM: 610709) testis-specific serine/th ( 367) 2475 207.6 3.8e-53
NP_443732 (OMIM: 610710) testis-specific serine/th ( 358) 1597 139.2 1.4e-32
NP_443073 (OMIM: 607660) testis-specific serine/th ( 268) 866 82.1 1.6e-15
NP_114426 (OMIM: 610712) testis-specific serine/th ( 273) 817 78.3 2.3e-14
XP_011527776 (OMIM: 605705,616341) PREDICTED: seri ( 734) 702 70.1 1.9e-11
XP_016872913 (OMIM: 614776) PREDICTED: serine/thre (1213) 702 70.4 2.4e-11
NP_001268678 (OMIM: 614776) serine/threonine-prote (1261) 702 70.5 2.4e-11
XP_005271539 (OMIM: 614776) PREDICTED: serine/thre (1321) 702 70.5 2.5e-11
NP_775490 (OMIM: 605705,616341) serine/threonine-p ( 783) 696 69.6 2.7e-11
XP_011541028 (OMIM: 614776) PREDICTED: serine/thre ( 660) 682 68.4 5.2e-11
XP_005271541 (OMIM: 614776) PREDICTED: serine/thre (1261) 682 68.9 7.2e-11
XP_011541024 (OMIM: 614776) PREDICTED: serine/thre (1309) 682 68.9 7.3e-11
NP_079440 (OMIM: 614776) serine/threonine-protein (1321) 682 68.9 7.3e-11
XP_011541023 (OMIM: 614776) PREDICTED: serine/thre (1369) 682 69.0 7.5e-11
XP_005271538 (OMIM: 614776) PREDICTED: serine/thre (1369) 682 69.0 7.5e-11
NP_056006 (OMIM: 608973) serine/threonine-protein ( 926) 662 67.1 1.8e-10
NP_001273055 (OMIM: 606511) serine/threonine-prote ( 780) 648 65.9 3.5e-10
XP_005273191 (OMIM: 606511) PREDICTED: serine/thre ( 781) 648 65.9 3.5e-10
XP_011507863 (OMIM: 606511) PREDICTED: serine/thre ( 788) 648 65.9 3.6e-10
NP_061120 (OMIM: 606511) serine/threonine-protein ( 795) 648 65.9 3.6e-10
NP_001273053 (OMIM: 606511) serine/threonine-prote ( 796) 648 65.9 3.6e-10
XP_005267700 (OMIM: 602678) PREDICTED: MAP/microtu ( 643) 645 65.5 3.8e-10
XP_016876782 (OMIM: 602678) PREDICTED: MAP/microtu ( 708) 645 65.6 4e-10
NP_001156769 (OMIM: 600526) serine/threonine-prote ( 709) 645 65.6 4e-10
NP_001122392 (OMIM: 602678) MAP/microtubule affini ( 713) 645 65.6 4e-10
NP_001156768 (OMIM: 600526) serine/threonine-prote ( 719) 645 65.6 4e-10
XP_016876781 (OMIM: 602678) PREDICTED: MAP/microtu ( 722) 645 65.6 4e-10
NP_004945 (OMIM: 600526) serine/threonine-protein ( 724) 645 65.6 4e-10
XP_016876780 (OMIM: 602678) PREDICTED: MAP/microtu ( 728) 645 65.6 4e-10
XP_011543100 (OMIM: 600526) PREDICTED: serine/thre ( 729) 645 65.6 4e-10
NP_002367 (OMIM: 602678) MAP/microtubule affinity- ( 729) 645 65.6 4e-10
XP_005267699 (OMIM: 602678) PREDICTED: MAP/microtu ( 737) 645 65.6 4.1e-10
XP_005267698 (OMIM: 602678) PREDICTED: MAP/microtu ( 738) 645 65.6 4.1e-10
XP_016872800 (OMIM: 600526) PREDICTED: serine/thre ( 738) 645 65.6 4.1e-10
XP_011543099 (OMIM: 600526) PREDICTED: serine/thre ( 739) 645 65.6 4.1e-10
XP_006720209 (OMIM: 602678) PREDICTED: MAP/microtu ( 739) 645 65.6 4.1e-10
XP_011543098 (OMIM: 600526) PREDICTED: serine/thre ( 744) 645 65.6 4.1e-10
NP_001122391 (OMIM: 602678) MAP/microtubule affini ( 744) 645 65.6 4.1e-10
NP_059672 (OMIM: 600526) serine/threonine-protein ( 745) 645 65.6 4.1e-10
XP_011543097 (OMIM: 600526) PREDICTED: serine/thre ( 745) 645 65.6 4.1e-10
NP_001122390 (OMIM: 602678) MAP/microtubule affini ( 753) 645 65.6 4.1e-10
XP_011543096 (OMIM: 600526) PREDICTED: serine/thre ( 753) 645 65.6 4.1e-10
XP_016872799 (OMIM: 600526) PREDICTED: serine/thre ( 763) 645 65.7 4.1e-10
XP_011543095 (OMIM: 600526) PREDICTED: serine/thre ( 784) 645 65.7 4.2e-10
NP_001034558 (OMIM: 600526) serine/threonine-prote ( 788) 645 65.7 4.2e-10
XP_011543094 (OMIM: 600526) PREDICTED: serine/thre ( 793) 645 65.7 4.2e-10
XP_011543093 (OMIM: 600526) PREDICTED: serine/thre ( 798) 645 65.7 4.2e-10
XP_011543092 (OMIM: 600526) PREDICTED: serine/thre ( 799) 645 65.7 4.2e-10
XP_011543091 (OMIM: 600526) PREDICTED: serine/thre ( 808) 645 65.7 4.2e-10
NP_113605 (OMIM: 606495) MAP/microtubule affinity- ( 688) 631 64.5 8.3e-10
>>NP_114417 (OMIM: 610709) testis-specific serine/threon (367 aa)
initn: 2475 init1: 2475 opt: 2475 Z-score: 1075.2 bits: 207.6 E(85289): 3.8e-53
Smith-Waterman score: 2475; 100.0% identity (100.0% similar) in 367 aa overlap (1-367:1-367)
10 20 30 40 50 60
pF1KE0 MDDAAVLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 MDDAAVLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPRE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 IEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 IEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 SLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 SLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 YAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 YAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 LTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQPKARGSPSVAINKEGESSRGTEPLWTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 LTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQPKARGSPSVAINKEGESSRGTEPLWTP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 EPGSDKKSATKLEPEGEAQPQAQPETKPEGTAMQMSRQSEILGFPSKPSTMETEEGPPQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 EPGSDKKSATKLEPEGEAQPQAQPETKPEGTAMQMSRQSEILGFPSKPSTMETEEGPPQQ
310 320 330 340 350 360
pF1KE0 PPETRAQ
:::::::
NP_114 PPETRAQ
>>NP_443732 (OMIM: 610710) testis-specific serine/threon (358 aa)
initn: 1602 init1: 1566 opt: 1597 Z-score: 705.9 bits: 139.2 E(85289): 1.4e-32
Smith-Waterman score: 1597; 71.8% identity (89.4% similar) in 330 aa overlap (1-327:1-330)
10 20 30 40 50 60
pF1KE0 MDDAAVLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPRE
::::.::...::..:::::.:::::::::::::::::::.:::::::.:.::.:.:::::
NP_443 MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPRE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 IEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQL
..::: .:: :::::::::::: :..::.:::.:::::::.:: .:::::: ::: :.::
NP_443 MDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 SLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPA
: :.:::::::.:::::::.:::::::::::::::.::::::::..::. :::::::: :
NP_443 SSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 YAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKH
::::::::.::::::::::::::::::::::::::::::.:.:::::::::::.:::::.
NP_443 YAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKN
190 200 210 220 230 240
250 260 270 280 290
pF1KE0 LTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQP-KARGSPSVAINKEGESSRGTEPLWT
:: :::::::.::::::..:::::::::: :.:: : ... :.....:::.. .:
NP_443 LTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQPPKPKATSSASFKREGEGKYRAECKLD
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE0 PEPG--SDKKSATKLEPEGEAQPQAQPETKPEGTAMQMSRQSEILGFPSKPSTMETEEGP
. : :.. :: . . . . ::..
NP_443 TKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAETSRAKDHHISGAEVGKAST
310 320 330 340 350
>>NP_443073 (OMIM: 607660) testis-specific serine/threon (268 aa)
initn: 825 init1: 447 opt: 866 Z-score: 399.5 bits: 82.1 E(85289): 1.6e-15
Smith-Waterman score: 866; 47.4% identity (76.5% similar) in 272 aa overlap (1-272:1-265)
10 20 30 40 50 60
pF1KE0 MDDAAVLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPRE
:.: : :: :: ..:::.:.::: :.:.. . .::::.::. .: .:...:::::
NP_443 MED--FLLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRE
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 IEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQL
..:. :.: .::..::..:.. ::. .::::: ::... . . : : :..:. :.:.
NP_443 LQIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 SLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPA
::.::: :.::::::.: :: . ::.::.::.:.: . : : ::.::::: :
NP_443 VEAIRYCHGCGVAHRDLKCENALL-QGFNLKLTDFGFAK--VLPKSHR-ELSQTFCGSTA
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 YAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKH
:::::::::::.. : :.::.::.::.:.:.:.:.::..: ::: :... :.::
NP_443 YAAPEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLW-QQQKGVSFPTHLS
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE0 LTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQPKARGSPSVAINKEGESSRGTEPLWTP
....:.::. ..:.::. : :.:. : :.
NP_443 ISADCQDLLKRLLEPDMILRPSIEEVSWHPWLAST
240 250 260
310 320 330 340 350 360
pF1KE0 EPGSDKKSATKLEPEGEAQPQAQPETKPEGTAMQMSRQSEILGFPSKPSTMETEEGPPQQ
>>NP_114426 (OMIM: 610712) testis-specific serine/threon (273 aa)
initn: 771 init1: 302 opt: 817 Z-score: 378.8 bits: 78.3 E(85289): 2.3e-14
Smith-Waterman score: 817; 46.2% identity (72.0% similar) in 279 aa overlap (1-278:1-273)
10 20 30 40 50 60
pF1KE0 MDDAAVLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPRE
:. .:.. :: :: ..:::::.::: : :.. : .::::..::..:: ::..::::::
NP_114 MSGDKLLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 IEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQL
. :: . : :....:..:. .::.::::: :. :::. .. : . .:: : :.
NP_114 LSILRGVRHPHIVHVFEFIEVCNGKLYIVMEAAAT-DLLQAVQRNGRIPGVQARDLFAQI
70 80 90 100 110
130 140 150 160 170
pF1KE0 SLAIKYCHDLDVVHRDLKCDNLLLDKDFN-IKLSDFSFSKRCLRDDSGRMALSKTFCGSP
. :..: :: .:::::::.:.::. : .::.::.:. :. : :: :.:::
NP_114 AGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFG----RQAHGYPDLSTTYCGSA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 AYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSK
:::.:::: ::::.:: ::.::.::.::.:: : ::.:::.: . : ::. : .:..
NP_114 AYASPEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQKRG-VLYPEGL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 HLTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQPKARGSPSVAINKEGESSRGTEPLWT
.:. .:: :: ..:: . . : .. .::.. :
NP_114 ELSERCKALIAELLQFSPSARPSAGQVARNCWLRAGDSG
240 250 260 270
300 310 320 330 340 350
pF1KE0 PEPGSDKKSATKLEPEGEAQPQAQPETKPEGTAMQMSRQSEILGFPSKPSTMETEEGPPQ
>>XP_011527776 (OMIM: 605705,616341) PREDICTED: serine/t (734 aa)
initn: 750 init1: 264 opt: 702 Z-score: 326.6 bits: 70.1 E(85289): 1.9e-11
Smith-Waterman score: 702; 39.2% identity (64.7% similar) in 334 aa overlap (18-341:33-356)
10 20 30 40
pF1KE0 MDDAAVLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKK
::.:..: :: : . : .:::::::. .
XP_011 IMSEFSADPAGQGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTR
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 APADFLEKFLPREIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGA
.. :::. ::.... .::: ::: :...::. .::: :.: .:.... . . :
XP_011 LDSSNLEKIY-REVQLMKLLNHPHIIKLYQVMETKD-MLYIVTEFAKNGEMFDYLTSNGH
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 LHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSG
: :.:::::: :. :..:::: .:::::: .::::: ...:::.::.:.. ::
XP_011 LSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLADFGFGNF---YKSG
130 140 150 160 170
170 180 190 200 210 220
pF1KE0 RMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRI
. :: :.:::: ::::::..: :. :::::::.::..::::.:.: :. . .
XP_011 E-PLS-TWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQR
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE0 QKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCWM--QPKARGSPSVAIN
: : .: .. .:..:: .:: : ::. : .: .: :: .: : :..
XP_011 VLEGRFRIPF--FMSQDCESLIRRMLVVDPARRITIAQIRQHRWMRAEPCLPGPACPAFS
240 250 260 270 280 290
290 300 310 320 330
pF1KE0 KEGESSR----GTEPLWTPEP-GSDKKSATKLEPEGEAQPQAQPET---KPEGTAMQMSR
.. .: . : . : :.. .... :: . .: .:. : .:
XP_011 AHSYTSNLGDYDEQALGIMQTLGVDRQRTVEVPQEGLSTDPFRPALLCPQPQ-TLVQSVL
300 310 320 330 340 350
340 350 360
pF1KE0 QSEILGFPSKPSTMETEEGPPQQPPETRAQ
:.:.
XP_011 QAEMDCELQSSLQWPLFFPVDASCSGVFRPRPVSPSSLLDTAISEEARQGPGLEEEQDTQ
360 370 380 390 400 410
>>XP_016872913 (OMIM: 614776) PREDICTED: serine/threonin (1213 aa)
initn: 657 init1: 245 opt: 702 Z-score: 324.7 bits: 70.4 E(85289): 2.4e-11
Smith-Waterman score: 707; 38.2% identity (65.4% similar) in 356 aa overlap (9-340:62-404)
10 20 30
pF1KE0 MDDAAVLKRRGYL-LGINLGEGSYAKVKSAYSERLKFN
: :: . ..:.:..: :: : : .
XP_016 PGSPAAPAAVSPAAGQPRPPAPASRGPMPARIGYYEIDRTIGKGNFAVVKRATHLVTKAK
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE0 VAIKIIDRKKAPADFLEKFLPREIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGD
:::::::. . . :.:.. ::..:. :: : ::. :...:: . .:.: : : :.
XP_016 VAIKIIDKTQLDEENLKKIF-REVQIMKMLCHPHIIRLYQVMETER-MIYLVTEYASGGE
100 110 120 130 140
100 110 120 130 140 150
pF1KE0 LLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSF
... . ..: . : :::.::.:. :. .:: ..:::::: .::::: ..:::..::.:
XP_016 IFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGF
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE0 SKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQ-PKVYDIWSLGVILYIMVCGSMPY
:. :. : ::.:::: :::::...: :. ::: :::::::.::..:::..:.
XP_016 SNLFT---PGQ--LLKTWCGSPPYAAPELFEGKEYDGPKV-DIWSLGVVLYVLVCGALPF
210 220 230 240 250 260
220 230 240 250 260 270
pF1KE0 DDSNIKKM-LRIQK-EHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQP
: :..... :. . . :. : .. ::. :: ::: : :.:: ...: .: ::.
XP_016 DGSTLQNLRARVLSGKFRIPF----FMSTECEHLIRHMLVLDPNKRLSMEQICKHKWMK-
270 280 290 300 310
280 290 300 310 320
pF1KE0 KARGSPS----VAINKEGESSRGTEPL------WTPEPGSDKKSATKLEPEGEAQ----P
. ..:. .: .. . : ..:: . : ::... . : : :. :
XP_016 LGDADPNFDRLIAECQQLKEERQVDPLNEDVLLAMEDMGLDKEQTLQAEQAGTAMNISVP
320 330 340 350 360 370
330 340 350 360
pF1KE0 QAQ---PETK---PEGTAMQMSRQSEILGFPSKPSTMETEEGPPQQPPETRAQ
:.: ::.. :.:: : ..:
XP_016 QVQLINPENQIVEPDGTLNLDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMEDLQKL
380 390 400 410 420 430
>>NP_001268678 (OMIM: 614776) serine/threonine-protein k (1261 aa)
initn: 657 init1: 245 opt: 702 Z-score: 324.6 bits: 70.5 E(85289): 2.4e-11
Smith-Waterman score: 707; 38.2% identity (65.4% similar) in 356 aa overlap (9-340:62-404)
10 20 30
pF1KE0 MDDAAVLKRRGYL-LGINLGEGSYAKVKSAYSERLKFN
: :: . ..:.:..: :: : : .
NP_001 PGSPAAPAAVSPAAGQPRPPAPASRGPMPARIGYYEIDRTIGKGNFAVVKRATHLVTKAK
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE0 VAIKIIDRKKAPADFLEKFLPREIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGD
:::::::. . . :.:.. ::..:. :: : ::. :...:: . .:.: : : :.
NP_001 VAIKIIDKTQLDEENLKKIF-REVQIMKMLCHPHIIRLYQVMETER-MIYLVTEYASGGE
100 110 120 130 140
100 110 120 130 140 150
pF1KE0 LLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSF
... . ..: . : :::.::.:. :. .:: ..:::::: .::::: ..:::..::.:
NP_001 IFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGF
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE0 SKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQ-PKVYDIWSLGVILYIMVCGSMPY
:. :. : ::.:::: :::::...: :. ::: :::::::.::..:::..:.
NP_001 SNLFT---PGQ--LLKTWCGSPPYAAPELFEGKEYDGPKV-DIWSLGVVLYVLVCGALPF
210 220 230 240 250 260
220 230 240 250 260 270
pF1KE0 DDSNIKKM-LRIQK-EHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQP
: :..... :. . . :. : .. ::. :: ::: : :.:: ...: .: ::.
NP_001 DGSTLQNLRARVLSGKFRIPF----FMSTECEHLIRHMLVLDPNKRLSMEQICKHKWMK-
270 280 290 300 310
280 290 300 310 320
pF1KE0 KARGSPS----VAINKEGESSRGTEPL------WTPEPGSDKKSATKLEPEGEAQ----P
. ..:. .: .. . : ..:: . : ::... . : : :. :
NP_001 LGDADPNFDRLIAECQQLKEERQVDPLNEDVLLAMEDMGLDKEQTLQAEQAGTAMNISVP
320 330 340 350 360 370
330 340 350 360
pF1KE0 QAQ---PETK---PEGTAMQMSRQSEILGFPSKPSTMETEEGPPQQPPETRAQ
:.: ::.. :.:: : ..:
NP_001 QVQLINPENQIVEPDGTLNLDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMEDLQKL
380 390 400 410 420 430
>>XP_005271539 (OMIM: 614776) PREDICTED: serine/threonin (1321 aa)
initn: 657 init1: 245 opt: 702 Z-score: 324.4 bits: 70.5 E(85289): 2.5e-11
Smith-Waterman score: 707; 38.2% identity (65.4% similar) in 356 aa overlap (9-340:62-404)
10 20 30
pF1KE0 MDDAAVLKRRGYL-LGINLGEGSYAKVKSAYSERLKFN
: :: . ..:.:..: :: : : .
XP_005 PGSPAAPAAVSPAAGQPRPPAPASRGPMPARIGYYEIDRTIGKGNFAVVKRATHLVTKAK
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE0 VAIKIIDRKKAPADFLEKFLPREIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGD
:::::::. . . :.:.. ::..:. :: : ::. :...:: . .:.: : : :.
XP_005 VAIKIIDKTQLDEENLKKIF-REVQIMKMLCHPHIIRLYQVMETER-MIYLVTEYASGGE
100 110 120 130 140
100 110 120 130 140 150
pF1KE0 LLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSF
... . ..: . : :::.::.:. :. .:: ..:::::: .::::: ..:::..::.:
XP_005 IFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGF
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE0 SKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQ-PKVYDIWSLGVILYIMVCGSMPY
:. :. : ::.:::: :::::...: :. ::: :::::::.::..:::..:.
XP_005 SNLFT---PGQ--LLKTWCGSPPYAAPELFEGKEYDGPKV-DIWSLGVVLYVLVCGALPF
210 220 230 240 250 260
220 230 240 250 260 270
pF1KE0 DDSNIKKM-LRIQK-EHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQP
: :..... :. . . :. : .. ::. :: ::: : :.:: ...: .: ::.
XP_005 DGSTLQNLRARVLSGKFRIPF----FMSTECEHLIRHMLVLDPNKRLSMEQICKHKWMK-
270 280 290 300 310
280 290 300 310 320
pF1KE0 KARGSPS----VAINKEGESSRGTEPL------WTPEPGSDKKSATKLEPEGEAQ----P
. ..:. .: .. . : ..:: . : ::... . : : :. :
XP_005 LGDADPNFDRLIAECQQLKEERQVDPLNEDVLLAMEDMGLDKEQTLQAEQAGTAMNISVP
320 330 340 350 360 370
330 340 350 360
pF1KE0 QAQ---PETK---PEGTAMQMSRQSEILGFPSKPSTMETEEGPPQQPPETRAQ
:.: ::.. :.:: : ..:
XP_005 QVQLINPENQIVEPDGTLNLDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMEDLQKL
380 390 400 410 420 430
>>NP_775490 (OMIM: 605705,616341) serine/threonine-prote (783 aa)
initn: 730 init1: 263 opt: 696 Z-score: 323.9 bits: 69.6 E(85289): 2.7e-11
Smith-Waterman score: 696; 43.5% identity (68.8% similar) in 276 aa overlap (18-291:33-299)
10 20 30 40
pF1KE0 MDDAAVLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKK
::.:..: :: : . : .:::::::. .
NP_775 IMSEFSADPAGQGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTR
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 APADFLEKFLPREIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGA
.. :::. ::.... .::: ::: :...::. .::: :.: .:.... . . :
NP_775 LDSSNLEKIY-REVQLMKLLNHPHIIKLYQVMETKD-MLYIVTEFAKNGEMFDYLTSNGH
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 LHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSG
: :.:::::: :. :..:::: .:::::: .::::: ...:::.::.:.. ::
NP_775 LSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLADFGFGN---FYKSG
130 140 150 160 170
170 180 190 200 210 220
pF1KE0 RMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRI
. :: :.:::: ::::::..: :. :::::::.::..::::.:.: :. . .
NP_775 E-PLS-TWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQR
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE0 QKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCWM--QPKARGSPSVAIN
: : .: .. .:..:: .:: : ::. : .: .: :: .: : :..
NP_775 VLEGRFRIPF--FMSQDCESLIRRMLVVDPARRITIAQIRQHRWMRAEPCLPGPACPAFS
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE0 KEGESSRGTEPLWTPEPGSDKKSATKLEPEGEAQPQAQPETKPEGTAMQMSRQSEILGFP
.. .:
NP_775 AHSYTSNLGDYDEQALGIMQTLGVDRQRTVESLQNSSYNHFAAIYYLLLERLKEYRNAQC
300 310 320 330 340 350
>>XP_011541028 (OMIM: 614776) PREDICTED: serine/threonin (660 aa)
initn: 682 init1: 245 opt: 682 Z-score: 318.6 bits: 68.4 E(85289): 5.2e-11
Smith-Waterman score: 682; 42.8% identity (70.6% similar) in 269 aa overlap (9-273:62-318)
10 20 30
pF1KE0 MDDAAVLKRRGYL-LGINLGEGSYAKVKSAYSERLKFN
: :: . ..:.:..: :: : : .
XP_011 PGSPAAPAAVSPAAGQPRPPAPASRGPMPARIGYYEIDRTIGKGNFAVVKRATHLVTKAK
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE0 VAIKIIDRKKAPADFLEKFLPREIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGD
:::::::. . . :.:.. ::..:. :: : ::. :...:: . .:.: : : :.
XP_011 VAIKIIDKTQLDEENLKKIF-REVQIMKMLCHPHIIRLYQVMETER-MIYLVTEYASGGE
100 110 120 130 140
100 110 120 130 140 150
pF1KE0 LLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSF
... . ..: . : :::.::.:. :. .:: ..:::::: .::::: ..:::..::.:
XP_011 IFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGF
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE0 SKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQ-PKVYDIWSLGVILYIMVCGSMPY
:. :. : ::.:::: :::::...: :. ::: :::::::.::..:::..:.
XP_011 SNLF---TPGQ--LLKTWCGSPPYAAPELFEGKEYDGPKV-DIWSLGVVLYVLVCGALPF
210 220 230 240 250 260
220 230 240 250 260 270
pF1KE0 DDSNIKKM-LRIQK-EHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQP
: :..... :. . . :. : .. ::. :: ::: : :.:: ...: .: ::.
XP_011 DGSTLQNLRARVLSGKFRIPF----FMSTECEHLIRHMLVLDPNKRLSMEQICKHKWMKL
270 280 290 300 310
280 290 300 310 320 330
pF1KE0 KARGSPSVAINKEGESSRGTEPLWTPEPGSDKKSATKLEPEGEAQPQAQPETKPEGTAMQ
XP_011 GDADPNFDRLIAECQQLKEERQVDPLNEDVLLAMEDMGLDKEQTLQSLRSDAYDHYSAIY
320 330 340 350 360 370
367 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 04:39:54 2016 done: Sat Nov 5 04:39:55 2016
Total Scan time: 9.200 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]