Result of FASTA (omim) for
pF1KE0944
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0944, 343 aa
1>>>pF1KE0944 343 - 343 aa - 343 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.8174+/-0.000464; mu= -5.7852+/- 0.028
mean_var=530.7022+/-117.078, 0's: 0 Z-trim(117.8): 841 B-trim: 33 in 1/59
Lambda= 0.055674
statistics sampled from 28965 (30101) to 28965 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.716), E-opt: 0.2 (0.353), width: 16
Scan time: 7.750
The best scores are: opt bits E(85289)
NP_067675 (OMIM: 609462) tribbles homolog 2 [Homo ( 343) 2306 200.3 5.2e-51
NP_079471 (OMIM: 609461) tribbles homolog 1 isofor ( 372) 1266 116.8 7.6e-26
NP_001269914 (OMIM: 609461) tribbles homolog 1 iso ( 206) 987 94.0 3.1e-19
NP_001288122 (OMIM: 607898) tribbles homolog 3 iso ( 358) 979 93.7 6.5e-19
NP_066981 (OMIM: 607898) tribbles homolog 3 isofor ( 358) 979 93.7 6.5e-19
NP_001288125 (OMIM: 607898) tribbles homolog 3 iso ( 358) 979 93.7 6.5e-19
NP_001288117 (OMIM: 607898) tribbles homolog 3 iso ( 358) 979 93.7 6.5e-19
NP_001288119 (OMIM: 607898) tribbles homolog 3 iso ( 358) 979 93.7 6.5e-19
NP_001288130 (OMIM: 607898) tribbles homolog 3 iso ( 385) 979 93.7 6.8e-19
XP_016883478 (OMIM: 607898) PREDICTED: tribbles ho ( 385) 979 93.7 6.8e-19
XP_011516388 (OMIM: 607025) PREDICTED: maternal em ( 373) 433 49.9 1.1e-05
NP_001243614 (OMIM: 607025) maternal embryonic leu ( 610) 433 50.2 1.4e-05
XP_011516382 (OMIM: 607025) PREDICTED: maternal em ( 622) 433 50.2 1.4e-05
XP_011516378 (OMIM: 607025) PREDICTED: maternal em ( 651) 433 50.2 1.4e-05
XP_011516379 (OMIM: 607025) PREDICTED: maternal em ( 651) 433 50.2 1.4e-05
NP_055606 (OMIM: 607025) maternal embryonic leucin ( 651) 433 50.2 1.4e-05
XP_011516380 (OMIM: 607025) PREDICTED: maternal em ( 651) 433 50.2 1.4e-05
XP_011516381 (OMIM: 607025) PREDICTED: maternal em ( 651) 433 50.2 1.4e-05
XP_011516385 (OMIM: 607025) PREDICTED: maternal em ( 619) 426 49.6 2.1e-05
NP_001243618 (OMIM: 607025) maternal embryonic leu ( 619) 426 49.6 2.1e-05
XP_011516383 (OMIM: 607025) PREDICTED: maternal em ( 619) 426 49.6 2.1e-05
XP_011516384 (OMIM: 607025) PREDICTED: maternal em ( 619) 426 49.6 2.1e-05
XP_011516386 (OMIM: 607025) PREDICTED: maternal em ( 619) 426 49.6 2.1e-05
NP_115806 (OMIM: 609235) serine/threonine-protein ( 778) 418 49.2 3.6e-05
NP_006243 (OMIM: 600497) 5'-AMP-activated protein ( 552) 407 48.0 5.6e-05
NP_742081 (OMIM: 607707) calcium/calmodulin-depend ( 449) 404 47.7 5.9e-05
XP_011516387 (OMIM: 607025) PREDICTED: maternal em ( 568) 406 48.0 6e-05
NP_001243619 (OMIM: 607025) maternal embryonic leu ( 580) 406 48.0 6.1e-05
NP_742080 (OMIM: 607707) calcium/calmodulin-depend ( 479) 404 47.7 6.1e-05
NP_742079 (OMIM: 607707) calcium/calmodulin-depend ( 492) 404 47.7 6.2e-05
XP_016868154 (OMIM: 607707) PREDICTED: calcium/cal ( 493) 404 47.7 6.2e-05
XP_005249921 (OMIM: 607707) PREDICTED: calcium/cal ( 494) 404 47.7 6.2e-05
XP_016868153 (OMIM: 607707) PREDICTED: calcium/cal ( 502) 404 47.7 6.3e-05
NP_742078 (OMIM: 607707) calcium/calmodulin-depend ( 503) 404 47.7 6.3e-05
NP_742077 (OMIM: 607707) calcium/calmodulin-depend ( 517) 404 47.8 6.4e-05
XP_006715847 (OMIM: 607707) PREDICTED: calcium/cal ( 518) 404 47.8 6.4e-05
NP_742076 (OMIM: 607707) calcium/calmodulin-depend ( 518) 404 47.8 6.4e-05
XP_005249919 (OMIM: 607707) PREDICTED: calcium/cal ( 527) 404 47.8 6.4e-05
NP_742075 (OMIM: 607707) calcium/calmodulin-depend ( 542) 404 47.8 6.5e-05
NP_001280099 (OMIM: 607707) calcium/calmodulin-dep ( 542) 404 47.8 6.5e-05
XP_016868151 (OMIM: 607707) PREDICTED: calcium/cal ( 603) 404 47.9 6.9e-05
XP_011513860 (OMIM: 607707) PREDICTED: calcium/cal ( 607) 404 47.9 6.9e-05
NP_113605 (OMIM: 606495) MAP/microtubule affinity- ( 688) 405 48.0 7e-05
XP_006715844 (OMIM: 607707) PREDICTED: calcium/cal ( 626) 404 47.9 7.1e-05
XP_016868150 (OMIM: 607707) PREDICTED: calcium/cal ( 656) 404 47.9 7.2e-05
XP_011513859 (OMIM: 607707) PREDICTED: calcium/cal ( 660) 404 47.9 7.3e-05
XP_011513858 (OMIM: 607707) PREDICTED: calcium/cal ( 661) 404 47.9 7.3e-05
NP_001211 (OMIM: 607707) calcium/calmodulin-depend ( 666) 404 47.9 7.3e-05
XP_011513857 (OMIM: 607707) PREDICTED: calcium/cal ( 666) 404 47.9 7.3e-05
XP_011513856 (OMIM: 607707) PREDICTED: calcium/cal ( 669) 404 47.9 7.3e-05
>>NP_067675 (OMIM: 609462) tribbles homolog 2 [Homo sapi (343 aa)
initn: 2306 init1: 2306 opt: 2306 Z-score: 1036.8 bits: 200.3 E(85289): 5.2e-51
Smith-Waterman score: 2306; 100.0% identity (100.0% similar) in 343 aa overlap (1-343:1-343)
10 20 30 40 50 60
pF1KE0 MNIHRSTPITIARYGRSRNKTQDFEELSSIRSAEPSQSFSPNLGSPSPPETPNLSHCVSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 MNIHRSTPITIARYGRSRNKTQDFEELSSIRSAEPSQSFSPNLGSPSPPETPNLSHCVSC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 IGKYLLLEPLEGDHVFRAVHLHSGEELVCKVFDISCYQESLAPCFCLSAHSNINQITEII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 IGKYLLLEPLEGDHVFRAVHLHSGEELVCKVFDISCYQESLAPCFCLSAHSNINQITEII
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LGETKAYVFFERSYGDMHSFVRTCKKLREEEAARLFYQIASAVAHCHDGGLVLRDLKLRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 LGETKAYVFFERSYGDMHSFVRTCKKLREEEAARLFYQIASAVAHCHDGGLVLRDLKLRK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 FIFKDEERTRVKLESLEDAYILRGDDDSLSDKHGCPAYVSPEILNTSGSYSGKAADVWSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 FIFKDEERTRVKLESLEDAYILRGDDDSLSDKHGCPAYVSPEILNTSGSYSGKAADVWSL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 GVMLYTMLVGRYPFHDIEPSSLFSKIRRGQFNIPETLSPKAKCLIRSILRREPSERLTSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 GVMLYTMLVGRYPFHDIEPSSLFSKIRRGQFNIPETLSPKAKCLIRSILRREPSERLTSQ
250 260 270 280 290 300
310 320 330 340
pF1KE0 EILDHPWFSTDFSVSNSAYGAKEVSDQLVPDVNMEENLDPFFN
:::::::::::::::::::::::::::::::::::::::::::
NP_067 EILDHPWFSTDFSVSNSAYGAKEVSDQLVPDVNMEENLDPFFN
310 320 330 340
>>NP_079471 (OMIM: 609461) tribbles homolog 1 isoform 1 (372 aa)
initn: 1283 init1: 1215 opt: 1266 Z-score: 585.0 bits: 116.8 E(85289): 7.6e-26
Smith-Waterman score: 1275; 61.9% identity (81.2% similar) in 320 aa overlap (35-342:56-371)
10 20 30 40 50
pF1KE0 RSTPITIARYGRSRNKTQDFEELSSIRSAEPSQSFSPNLGSPSPPETPNLSHCV------
: . .:: ::: :. : . .
NP_079 TRGVPAKRLLDADDAAAVAAKCPRLSECSSPPDYLSPP-GSPCSPQPPPAAPGAGGGSGS
30 40 50 60 70 80
60 70 80 90 100 110
pF1KE0 ----SCIGKYLLLEPLEGDHVFRAVHLHSGEELVCKVFDISCYQESLAPCFCLSAHSNIN
: :. :::: : .:: ::. .:.:.:: :::: :. ::... : . : .::::.
NP_079 APGPSRIADYLLLPLAEREHVSRALCIHTGRELRCKVFPIKHYQDKIRPYIQLPSHSNIT
90 100 110 120 130 140
120 130 140 150 160 170
pF1KE0 QITEIILGETKAYVFFERSYGDMHSFVRTCKKLREEEAARLFYQIASAVAHCHDGGLVLR
:.:.::::::::::::...:::::.::. :.:::::::::: ::.:::::::....::
NP_079 GIVEVILGETKAYVFFEKDFGDMHSYVRSRKRLREEEAARLFKQIVSAVAHCHQSAIVLG
150 160 170 180 190 200
180 190 200 210 220 230
pF1KE0 DLKLRKFIFKDEERTRVKLESLEDAYILRGDDDSLSDKHGCPAYVSPEILNTSGSYSGKA
:::::::.:. ::::...::::::..:..:.::.::::::::::::::::::.:.:::::
NP_079 DLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDALSDKHGCPAYVSPEILNTTGTYSGKA
210 220 230 240 250 260
240 250 260 270 280 290
pF1KE0 ADVWSLGVMLYTMLVGRYPFHDIEPSSLFSKIRRGQFNIPETLSPKAKCLIRSILRREPS
::::::::::::.::::::::: .::.:::::::::: ::: .::::.:::::.::::::
NP_079 ADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRGQFCIPEHISPKARCLIRSLLRREPS
270 280 290 300 310 320
300 310 320 330 340
pF1KE0 ERLTSQEILDHPWFSTDFSVSNSAYGAKEV--SDQLVPDVNMEENLDPFFN
::::. ::: :::: :: . .: .:. :::.::. . . ... ::
NP_079 ERLTAPEILLHPWFE---SVLEPGYIDSEIGTSDQIVPEYQEDSDISSFFC
330 340 350 360 370
>>NP_001269914 (OMIM: 609461) tribbles homolog 1 isoform (206 aa)
initn: 1009 init1: 945 opt: 987 Z-score: 466.4 bits: 94.0 E(85289): 3.1e-19
Smith-Waterman score: 987; 70.2% identity (88.9% similar) in 208 aa overlap (137-342:1-205)
110 120 130 140 150 160
pF1KE0 LSAHSNINQITEIILGETKAYVFFERSYGDMHSFVRTCKKLREEEAARLFYQIASAVAHC
:::.::. :.:::::::::: ::.::::::
NP_001 MHSYVRSRKRLREEEAARLFKQIVSAVAHC
10 20 30
170 180 190 200 210 220
pF1KE0 HDGGLVLRDLKLRKFIFKDEERTRVKLESLEDAYILRGDDDSLSDKHGCPAYVSPEILNT
:....:: :::::::.:. ::::...::::::..:..:.::.::::::::::::::::::
NP_001 HQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDALSDKHGCPAYVSPEILNT
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE0 SGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSKIRRGQFNIPETLSPKAKCLIR
.:.:::::::::::::::::.::::::::: .::.:::::::::: ::: .::::.::::
NP_001 TGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRGQFCIPEHISPKARCLIR
100 110 120 130 140 150
290 300 310 320 330 340
pF1KE0 SILRREPSERLTSQEILDHPWFSTDFSVSNSAYGAKEV--SDQLVPDVNMEENLDPFFN
:.::::::::::. ::: :::: :: . .: .:. :::.::. . . ... ::
NP_001 SLLRREPSERLTAPEILLHPWFE---SVLEPGYIDSEIGTSDQIVPEYQEDSDISSFFC
160 170 180 190 200
>>NP_001288122 (OMIM: 607898) tribbles homolog 3 isoform (358 aa)
initn: 947 init1: 947 opt: 979 Z-score: 460.5 bits: 93.7 E(85289): 6.5e-19
Smith-Waterman score: 993; 46.9% identity (70.0% similar) in 337 aa overlap (5-331:2-338)
10 20 30 40 50
pF1KE0 MNIHRSTPITIARYGRSRNKTQDFEE-LSSIRSAE------PSQSFSPNLGSPSPPETPN
:.::.. . ::.: .... :.. : .. :. . : : ::: .:.
NP_001 MRATPLAAPAGSLSRKKRLELDDNLDTERPVQKRARSGPQPRLPPCLLPLSPPTAPD
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LSHCV---SCIGKYLLLEPLEGDHVFRAVHLHSGEELVCKVFDISCYQESLAPCFCLSAH
. : : .: :.:::: :: ....:.: .: : .:::. .. : : : :
NP_001 RATAVATASRLGPYVLLEPEEGGRAYQALHCPTGTEYTCKVYPVQEALAVLEPYARLPPH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 SNINQITEIILGETKAYVFFERSYGDMHSFVRTCKKLREEEAARLFYQIASAVAHCHDGG
... . ::.. : :.:: :..:::::.::. ... : ::: :: :.:.:.::::. :
NP_001 KHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHCHQHG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 LVLRDLKLRKFIFKDEERTRVKLESLEDAYILRGDDDSLSDKHGCPAYVSPEILNTSGSY
:::::::: .:.: :.:: .. ::.:::. .: : :::: :::.:::::.::::.. .::
NP_001 LVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASY
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 SGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSKIRRGQFNIPETLSPKAKCLIRSILR
:::::::::::: :.:::.:.:::.: :: ::.::::: . .: :: :.::.: .::
NP_001 SGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVRCLLR
240 250 260 270 280 290
300 310 320 330 340
pF1KE0 REPSERLTSQEILDHPWFSTDFSVSNSAYGAKEVSDQLVPDVNMEENLDPFFN
:::.::::. :: :::. : . . . :.:::
NP_001 REPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVVPDGLGLDEAREEEGDREVVLY
300 310 320 330 340 350
NP_001 G
>>NP_066981 (OMIM: 607898) tribbles homolog 3 isoform 1 (358 aa)
initn: 947 init1: 947 opt: 979 Z-score: 460.5 bits: 93.7 E(85289): 6.5e-19
Smith-Waterman score: 993; 46.9% identity (70.0% similar) in 337 aa overlap (5-331:2-338)
10 20 30 40 50
pF1KE0 MNIHRSTPITIARYGRSRNKTQDFEE-LSSIRSAE------PSQSFSPNLGSPSPPETPN
:.::.. . ::.: .... :.. : .. :. . : : ::: .:.
NP_066 MRATPLAAPAGSLSRKKRLELDDNLDTERPVQKRARSGPQPRLPPCLLPLSPPTAPD
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LSHCV---SCIGKYLLLEPLEGDHVFRAVHLHSGEELVCKVFDISCYQESLAPCFCLSAH
. : : .: :.:::: :: ....:.: .: : .:::. .. : : : :
NP_066 RATAVATASRLGPYVLLEPEEGGRAYQALHCPTGTEYTCKVYPVQEALAVLEPYARLPPH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 SNINQITEIILGETKAYVFFERSYGDMHSFVRTCKKLREEEAARLFYQIASAVAHCHDGG
... . ::.. : :.:: :..:::::.::. ... : ::: :: :.:.:.::::. :
NP_066 KHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHCHQHG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 LVLRDLKLRKFIFKDEERTRVKLESLEDAYILRGDDDSLSDKHGCPAYVSPEILNTSGSY
:::::::: .:.: :.:: .. ::.:::. .: : :::: :::.:::::.::::.. .::
NP_066 LVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASY
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 SGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSKIRRGQFNIPETLSPKAKCLIRSILR
:::::::::::: :.:::.:.:::.: :: ::.::::: . .: :: :.::.: .::
NP_066 SGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVRCLLR
240 250 260 270 280 290
300 310 320 330 340
pF1KE0 REPSERLTSQEILDHPWFSTDFSVSNSAYGAKEVSDQLVPDVNMEENLDPFFN
:::.::::. :: :::. : . . . :.:::
NP_066 REPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVVPDGLGLDEAREEEGDREVVLY
300 310 320 330 340 350
NP_066 G
>>NP_001288125 (OMIM: 607898) tribbles homolog 3 isoform (358 aa)
initn: 947 init1: 947 opt: 979 Z-score: 460.5 bits: 93.7 E(85289): 6.5e-19
Smith-Waterman score: 993; 46.9% identity (70.0% similar) in 337 aa overlap (5-331:2-338)
10 20 30 40 50
pF1KE0 MNIHRSTPITIARYGRSRNKTQDFEE-LSSIRSAE------PSQSFSPNLGSPSPPETPN
:.::.. . ::.: .... :.. : .. :. . : : ::: .:.
NP_001 MRATPLAAPAGSLSRKKRLELDDNLDTERPVQKRARSGPQPRLPPCLLPLSPPTAPD
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LSHCV---SCIGKYLLLEPLEGDHVFRAVHLHSGEELVCKVFDISCYQESLAPCFCLSAH
. : : .: :.:::: :: ....:.: .: : .:::. .. : : : :
NP_001 RATAVATASRLGPYVLLEPEEGGRAYQALHCPTGTEYTCKVYPVQEALAVLEPYARLPPH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 SNINQITEIILGETKAYVFFERSYGDMHSFVRTCKKLREEEAARLFYQIASAVAHCHDGG
... . ::.. : :.:: :..:::::.::. ... : ::: :: :.:.:.::::. :
NP_001 KHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHCHQHG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 LVLRDLKLRKFIFKDEERTRVKLESLEDAYILRGDDDSLSDKHGCPAYVSPEILNTSGSY
:::::::: .:.: :.:: .. ::.:::. .: : :::: :::.:::::.::::.. .::
NP_001 LVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASY
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 SGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSKIRRGQFNIPETLSPKAKCLIRSILR
:::::::::::: :.:::.:.:::.: :: ::.::::: . .: :: :.::.: .::
NP_001 SGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVRCLLR
240 250 260 270 280 290
300 310 320 330 340
pF1KE0 REPSERLTSQEILDHPWFSTDFSVSNSAYGAKEVSDQLVPDVNMEENLDPFFN
:::.::::. :: :::. : . . . :.:::
NP_001 REPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVVPDGLGLDEAREEEGDREVVLY
300 310 320 330 340 350
NP_001 G
>>NP_001288117 (OMIM: 607898) tribbles homolog 3 isoform (358 aa)
initn: 947 init1: 947 opt: 979 Z-score: 460.5 bits: 93.7 E(85289): 6.5e-19
Smith-Waterman score: 993; 46.9% identity (70.0% similar) in 337 aa overlap (5-331:2-338)
10 20 30 40 50
pF1KE0 MNIHRSTPITIARYGRSRNKTQDFEE-LSSIRSAE------PSQSFSPNLGSPSPPETPN
:.::.. . ::.: .... :.. : .. :. . : : ::: .:.
NP_001 MRATPLAAPAGSLSRKKRLELDDNLDTERPVQKRARSGPQPRLPPCLLPLSPPTAPD
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LSHCV---SCIGKYLLLEPLEGDHVFRAVHLHSGEELVCKVFDISCYQESLAPCFCLSAH
. : : .: :.:::: :: ....:.: .: : .:::. .. : : : :
NP_001 RATAVATASRLGPYVLLEPEEGGRAYQALHCPTGTEYTCKVYPVQEALAVLEPYARLPPH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 SNINQITEIILGETKAYVFFERSYGDMHSFVRTCKKLREEEAARLFYQIASAVAHCHDGG
... . ::.. : :.:: :..:::::.::. ... : ::: :: :.:.:.::::. :
NP_001 KHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHCHQHG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 LVLRDLKLRKFIFKDEERTRVKLESLEDAYILRGDDDSLSDKHGCPAYVSPEILNTSGSY
:::::::: .:.: :.:: .. ::.:::. .: : :::: :::.:::::.::::.. .::
NP_001 LVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASY
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 SGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSKIRRGQFNIPETLSPKAKCLIRSILR
:::::::::::: :.:::.:.:::.: :: ::.::::: . .: :: :.::.: .::
NP_001 SGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVRCLLR
240 250 260 270 280 290
300 310 320 330 340
pF1KE0 REPSERLTSQEILDHPWFSTDFSVSNSAYGAKEVSDQLVPDVNMEENLDPFFN
:::.::::. :: :::. : . . . :.:::
NP_001 REPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVVPDGLGLDEAREEEGDREVVLY
300 310 320 330 340 350
NP_001 G
>>NP_001288119 (OMIM: 607898) tribbles homolog 3 isoform (358 aa)
initn: 947 init1: 947 opt: 979 Z-score: 460.5 bits: 93.7 E(85289): 6.5e-19
Smith-Waterman score: 993; 46.9% identity (70.0% similar) in 337 aa overlap (5-331:2-338)
10 20 30 40 50
pF1KE0 MNIHRSTPITIARYGRSRNKTQDFEE-LSSIRSAE------PSQSFSPNLGSPSPPETPN
:.::.. . ::.: .... :.. : .. :. . : : ::: .:.
NP_001 MRATPLAAPAGSLSRKKRLELDDNLDTERPVQKRARSGPQPRLPPCLLPLSPPTAPD
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LSHCV---SCIGKYLLLEPLEGDHVFRAVHLHSGEELVCKVFDISCYQESLAPCFCLSAH
. : : .: :.:::: :: ....:.: .: : .:::. .. : : : :
NP_001 RATAVATASRLGPYVLLEPEEGGRAYQALHCPTGTEYTCKVYPVQEALAVLEPYARLPPH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 SNINQITEIILGETKAYVFFERSYGDMHSFVRTCKKLREEEAARLFYQIASAVAHCHDGG
... . ::.. : :.:: :..:::::.::. ... : ::: :: :.:.:.::::. :
NP_001 KHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHCHQHG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 LVLRDLKLRKFIFKDEERTRVKLESLEDAYILRGDDDSLSDKHGCPAYVSPEILNTSGSY
:::::::: .:.: :.:: .. ::.:::. .: : :::: :::.:::::.::::.. .::
NP_001 LVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASY
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 SGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSKIRRGQFNIPETLSPKAKCLIRSILR
:::::::::::: :.:::.:.:::.: :: ::.::::: . .: :: :.::.: .::
NP_001 SGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVRCLLR
240 250 260 270 280 290
300 310 320 330 340
pF1KE0 REPSERLTSQEILDHPWFSTDFSVSNSAYGAKEVSDQLVPDVNMEENLDPFFN
:::.::::. :: :::. : . . . :.:::
NP_001 REPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVVPDGLGLDEAREEEGDREVVLY
300 310 320 330 340 350
NP_001 G
>>NP_001288130 (OMIM: 607898) tribbles homolog 3 isoform (385 aa)
initn: 947 init1: 947 opt: 979 Z-score: 460.2 bits: 93.7 E(85289): 6.8e-19
Smith-Waterman score: 993; 46.9% identity (70.0% similar) in 337 aa overlap (5-331:29-365)
10 20 30
pF1KE0 MNIHRSTPITIARYGRSRNKTQDFEE-LSSIRSAE-
:.::.. . ::.: .... :.. : ..
NP_001 MVLMHLAVKNNRMSANNDHFLTPTWQQMRATPLAAPAGSLSRKKRLELDDNLDTERPVQK
10 20 30 40 50 60
40 50 60 70 80
pF1KE0 -----PSQSFSPNLGSPSPPETPNLSHCV---SCIGKYLLLEPLEGDHVFRAVHLHSGEE
:. . : : ::: .:. . : : .: :.:::: :: ....:.: .: :
NP_001 RARSGPQPRLPPCLLPLSPPTAPDRATAVATASRLGPYVLLEPEEGGRAYQALHCPTGTE
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE0 LVCKVFDISCYQESLAPCFCLSAHSNINQITEIILGETKAYVFFERSYGDMHSFVRTCKK
.:::. .. : : : :... . ::.. : :.:: :..:::::.::. ..
NP_001 YTCKVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHR
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE0 LREEEAARLFYQIASAVAHCHDGGLVLRDLKLRKFIFKDEERTRVKLESLEDAYILRGDD
. : ::: :: :.:.:.::::. ::::::::: .:.: :.:: .. ::.:::. .: : :
NP_001 IPEPEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPD
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE0 DSLSDKHGCPAYVSPEILNTSGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSKI
::: :::.:::::.::::.. .:::::::::::::: :.:::.:.:::.: :: ::.::
NP_001 DSLWDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKI
250 260 270 280 290 300
270 280 290 300 310 320
pF1KE0 RRGQFNIPETLSPKAKCLIRSILRREPSERLTSQEILDHPWFSTDFSVSNSAYGAKEVSD
::: . .: :: :.::.: .:::::.::::. :: :::. : . . .
NP_001 RRGAYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAA
310 320 330 340 350 360
330 340
pF1KE0 QLVPDVNMEENLDPFFN
:.:::
NP_001 QVVPDGLGLDEAREEEGDREVVLYG
370 380
>>XP_016883478 (OMIM: 607898) PREDICTED: tribbles homolo (385 aa)
initn: 947 init1: 947 opt: 979 Z-score: 460.2 bits: 93.7 E(85289): 6.8e-19
Smith-Waterman score: 993; 46.9% identity (70.0% similar) in 337 aa overlap (5-331:29-365)
10 20 30
pF1KE0 MNIHRSTPITIARYGRSRNKTQDFEE-LSSIRSAE-
:.::.. . ::.: .... :.. : ..
XP_016 MVLMHLAVKNNRMSANNDHFLTPTWQQMRATPLAAPAGSLSRKKRLELDDNLDTERPVQK
10 20 30 40 50 60
40 50 60 70 80
pF1KE0 -----PSQSFSPNLGSPSPPETPNLSHCV---SCIGKYLLLEPLEGDHVFRAVHLHSGEE
:. . : : ::: .:. . : : .: :.:::: :: ....:.: .: :
XP_016 RARSGPQPRLPPCLLPLSPPTAPDRATAVATASRLGPYVLLEPEEGGRAYQALHCPTGTE
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE0 LVCKVFDISCYQESLAPCFCLSAHSNINQITEIILGETKAYVFFERSYGDMHSFVRTCKK
.:::. .. : : : :... . ::.. : :.:: :..:::::.::. ..
XP_016 YTCKVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHR
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE0 LREEEAARLFYQIASAVAHCHDGGLVLRDLKLRKFIFKDEERTRVKLESLEDAYILRGDD
. : ::: :: :.:.:.::::. ::::::::: .:.: :.:: .. ::.:::. .: : :
XP_016 IPEPEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPD
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE0 DSLSDKHGCPAYVSPEILNTSGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSKI
::: :::.:::::.::::.. .:::::::::::::: :.:::.:.:::.: :: ::.::
XP_016 DSLWDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKI
250 260 270 280 290 300
270 280 290 300 310 320
pF1KE0 RRGQFNIPETLSPKAKCLIRSILRREPSERLTSQEILDHPWFSTDFSVSNSAYGAKEVSD
::: . .: :: :.::.: .:::::.::::. :: :::. : . . .
XP_016 RRGAYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAA
310 320 330 340 350 360
330 340
pF1KE0 QLVPDVNMEENLDPFFN
:.:::
XP_016 QVVPDGLGLDEAREEEGDREVVLYG
370 380
343 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 04:38:48 2016 done: Sat Nov 5 04:38:49 2016
Total Scan time: 7.750 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]