Result of FASTA (ccds) for
pF1KE0944
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0944, 343 aa
1>>>pF1KE0944 343 - 343 aa - 343 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.1863+/-0.00106; mu= -9.0788+/- 0.061
mean_var=293.7399+/-66.956, 0's: 0 Z-trim(109.9): 358 B-trim: 0 in 0/53
Lambda= 0.074833
statistics sampled from 10758 (11185) to 10758 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.707), E-opt: 0.2 (0.344), width: 16
Scan time: 2.860
The best scores are: opt bits E(32554)
CCDS1683.1 TRIB2 gene_id:28951|Hs108|chr2 ( 343) 2306 262.7 3.1e-70
CCDS6357.1 TRIB1 gene_id:10221|Hs108|chr8 ( 372) 1266 150.5 2.1e-36
CCDS64971.1 TRIB1 gene_id:10221|Hs108|chr8 ( 206) 987 120.2 1.5e-27
CCDS12997.1 TRIB3 gene_id:57761|Hs108|chr20 ( 358) 979 119.5 4.3e-27
CCDS77554.1 TRIB3 gene_id:57761|Hs108|chr20 ( 385) 979 119.5 4.5e-27
>>CCDS1683.1 TRIB2 gene_id:28951|Hs108|chr2 (343 aa)
initn: 2306 init1: 2306 opt: 2306 Z-score: 1374.4 bits: 262.7 E(32554): 3.1e-70
Smith-Waterman score: 2306; 100.0% identity (100.0% similar) in 343 aa overlap (1-343:1-343)
10 20 30 40 50 60
pF1KE0 MNIHRSTPITIARYGRSRNKTQDFEELSSIRSAEPSQSFSPNLGSPSPPETPNLSHCVSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS16 MNIHRSTPITIARYGRSRNKTQDFEELSSIRSAEPSQSFSPNLGSPSPPETPNLSHCVSC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 IGKYLLLEPLEGDHVFRAVHLHSGEELVCKVFDISCYQESLAPCFCLSAHSNINQITEII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS16 IGKYLLLEPLEGDHVFRAVHLHSGEELVCKVFDISCYQESLAPCFCLSAHSNINQITEII
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LGETKAYVFFERSYGDMHSFVRTCKKLREEEAARLFYQIASAVAHCHDGGLVLRDLKLRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS16 LGETKAYVFFERSYGDMHSFVRTCKKLREEEAARLFYQIASAVAHCHDGGLVLRDLKLRK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 FIFKDEERTRVKLESLEDAYILRGDDDSLSDKHGCPAYVSPEILNTSGSYSGKAADVWSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS16 FIFKDEERTRVKLESLEDAYILRGDDDSLSDKHGCPAYVSPEILNTSGSYSGKAADVWSL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 GVMLYTMLVGRYPFHDIEPSSLFSKIRRGQFNIPETLSPKAKCLIRSILRREPSERLTSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS16 GVMLYTMLVGRYPFHDIEPSSLFSKIRRGQFNIPETLSPKAKCLIRSILRREPSERLTSQ
250 260 270 280 290 300
310 320 330 340
pF1KE0 EILDHPWFSTDFSVSNSAYGAKEVSDQLVPDVNMEENLDPFFN
:::::::::::::::::::::::::::::::::::::::::::
CCDS16 EILDHPWFSTDFSVSNSAYGAKEVSDQLVPDVNMEENLDPFFN
310 320 330 340
>>CCDS6357.1 TRIB1 gene_id:10221|Hs108|chr8 (372 aa)
initn: 1283 init1: 1215 opt: 1266 Z-score: 767.1 bits: 150.5 E(32554): 2.1e-36
Smith-Waterman score: 1275; 61.9% identity (81.2% similar) in 320 aa overlap (35-342:56-371)
10 20 30 40 50
pF1KE0 RSTPITIARYGRSRNKTQDFEELSSIRSAEPSQSFSPNLGSPSPPETPNLSHCV------
: . .:: ::: :. : . .
CCDS63 TRGVPAKRLLDADDAAAVAAKCPRLSECSSPPDYLSPP-GSPCSPQPPPAAPGAGGGSGS
30 40 50 60 70 80
60 70 80 90 100 110
pF1KE0 ----SCIGKYLLLEPLEGDHVFRAVHLHSGEELVCKVFDISCYQESLAPCFCLSAHSNIN
: :. :::: : .:: ::. .:.:.:: :::: :. ::... : . : .::::.
CCDS63 APGPSRIADYLLLPLAEREHVSRALCIHTGRELRCKVFPIKHYQDKIRPYIQLPSHSNIT
90 100 110 120 130 140
120 130 140 150 160 170
pF1KE0 QITEIILGETKAYVFFERSYGDMHSFVRTCKKLREEEAARLFYQIASAVAHCHDGGLVLR
:.:.::::::::::::...:::::.::. :.:::::::::: ::.:::::::....::
CCDS63 GIVEVILGETKAYVFFEKDFGDMHSYVRSRKRLREEEAARLFKQIVSAVAHCHQSAIVLG
150 160 170 180 190 200
180 190 200 210 220 230
pF1KE0 DLKLRKFIFKDEERTRVKLESLEDAYILRGDDDSLSDKHGCPAYVSPEILNTSGSYSGKA
:::::::.:. ::::...::::::..:..:.::.::::::::::::::::::.:.:::::
CCDS63 DLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDALSDKHGCPAYVSPEILNTTGTYSGKA
210 220 230 240 250 260
240 250 260 270 280 290
pF1KE0 ADVWSLGVMLYTMLVGRYPFHDIEPSSLFSKIRRGQFNIPETLSPKAKCLIRSILRREPS
::::::::::::.::::::::: .::.:::::::::: ::: .::::.:::::.::::::
CCDS63 ADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRGQFCIPEHISPKARCLIRSLLRREPS
270 280 290 300 310 320
300 310 320 330 340
pF1KE0 ERLTSQEILDHPWFSTDFSVSNSAYGAKEV--SDQLVPDVNMEENLDPFFN
::::. ::: :::: :: . .: .:. :::.::. . . ... ::
CCDS63 ERLTAPEILLHPWFE---SVLEPGYIDSEIGTSDQIVPEYQEDSDISSFFC
330 340 350 360 370
>>CCDS64971.1 TRIB1 gene_id:10221|Hs108|chr8 (206 aa)
initn: 1009 init1: 945 opt: 987 Z-score: 607.8 bits: 120.2 E(32554): 1.5e-27
Smith-Waterman score: 987; 70.2% identity (88.9% similar) in 208 aa overlap (137-342:1-205)
110 120 130 140 150 160
pF1KE0 LSAHSNINQITEIILGETKAYVFFERSYGDMHSFVRTCKKLREEEAARLFYQIASAVAHC
:::.::. :.:::::::::: ::.::::::
CCDS64 MHSYVRSRKRLREEEAARLFKQIVSAVAHC
10 20 30
170 180 190 200 210 220
pF1KE0 HDGGLVLRDLKLRKFIFKDEERTRVKLESLEDAYILRGDDDSLSDKHGCPAYVSPEILNT
:....:: :::::::.:. ::::...::::::..:..:.::.::::::::::::::::::
CCDS64 HQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDALSDKHGCPAYVSPEILNT
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE0 SGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSKIRRGQFNIPETLSPKAKCLIR
.:.:::::::::::::::::.::::::::: .::.:::::::::: ::: .::::.::::
CCDS64 TGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRGQFCIPEHISPKARCLIR
100 110 120 130 140 150
290 300 310 320 330 340
pF1KE0 SILRREPSERLTSQEILDHPWFSTDFSVSNSAYGAKEV--SDQLVPDVNMEENLDPFFN
:.::::::::::. ::: :::: :: . .: .:. :::.::. . . ... ::
CCDS64 SLLRREPSERLTAPEILLHPWFE---SVLEPGYIDSEIGTSDQIVPEYQEDSDISSFFC
160 170 180 190 200
>>CCDS12997.1 TRIB3 gene_id:57761|Hs108|chr20 (358 aa)
initn: 947 init1: 947 opt: 979 Z-score: 599.9 bits: 119.5 E(32554): 4.3e-27
Smith-Waterman score: 993; 46.9% identity (70.0% similar) in 337 aa overlap (5-331:2-338)
10 20 30 40 50
pF1KE0 MNIHRSTPITIARYGRSRNKTQDFEE-LSSIRSAE------PSQSFSPNLGSPSPPETPN
:.::.. . ::.: .... :.. : .. :. . : : ::: .:.
CCDS12 MRATPLAAPAGSLSRKKRLELDDNLDTERPVQKRARSGPQPRLPPCLLPLSPPTAPD
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LSHCV---SCIGKYLLLEPLEGDHVFRAVHLHSGEELVCKVFDISCYQESLAPCFCLSAH
. : : .: :.:::: :: ....:.: .: : .:::. .. : : : :
CCDS12 RATAVATASRLGPYVLLEPEEGGRAYQALHCPTGTEYTCKVYPVQEALAVLEPYARLPPH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 SNINQITEIILGETKAYVFFERSYGDMHSFVRTCKKLREEEAARLFYQIASAVAHCHDGG
... . ::.. : :.:: :..:::::.::. ... : ::: :: :.:.:.::::. :
CCDS12 KHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHCHQHG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 LVLRDLKLRKFIFKDEERTRVKLESLEDAYILRGDDDSLSDKHGCPAYVSPEILNTSGSY
:::::::: .:.: :.:: .. ::.:::. .: : :::: :::.:::::.::::.. .::
CCDS12 LVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASY
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 SGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSKIRRGQFNIPETLSPKAKCLIRSILR
:::::::::::: :.:::.:.:::.: :: ::.::::: . .: :: :.::.: .::
CCDS12 SGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVRCLLR
240 250 260 270 280 290
300 310 320 330 340
pF1KE0 REPSERLTSQEILDHPWFSTDFSVSNSAYGAKEVSDQLVPDVNMEENLDPFFN
:::.::::. :: :::. : . . . :.:::
CCDS12 REPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVVPDGLGLDEAREEEGDREVVLY
300 310 320 330 340 350
CCDS12 G
>>CCDS77554.1 TRIB3 gene_id:57761|Hs108|chr20 (385 aa)
initn: 947 init1: 947 opt: 979 Z-score: 599.5 bits: 119.5 E(32554): 4.5e-27
Smith-Waterman score: 993; 46.9% identity (70.0% similar) in 337 aa overlap (5-331:29-365)
10 20 30
pF1KE0 MNIHRSTPITIARYGRSRNKTQDFEE-LSSIRSAE-
:.::.. . ::.: .... :.. : ..
CCDS77 MVLMHLAVKNNRMSANNDHFLTPTWQQMRATPLAAPAGSLSRKKRLELDDNLDTERPVQK
10 20 30 40 50 60
40 50 60 70 80
pF1KE0 -----PSQSFSPNLGSPSPPETPNLSHCV---SCIGKYLLLEPLEGDHVFRAVHLHSGEE
:. . : : ::: .:. . : : .: :.:::: :: ....:.: .: :
CCDS77 RARSGPQPRLPPCLLPLSPPTAPDRATAVATASRLGPYVLLEPEEGGRAYQALHCPTGTE
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE0 LVCKVFDISCYQESLAPCFCLSAHSNINQITEIILGETKAYVFFERSYGDMHSFVRTCKK
.:::. .. : : : :... . ::.. : :.:: :..:::::.::. ..
CCDS77 YTCKVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHR
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE0 LREEEAARLFYQIASAVAHCHDGGLVLRDLKLRKFIFKDEERTRVKLESLEDAYILRGDD
. : ::: :: :.:.:.::::. ::::::::: .:.: :.:: .. ::.:::. .: : :
CCDS77 IPEPEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPD
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE0 DSLSDKHGCPAYVSPEILNTSGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSKI
::: :::.:::::.::::.. .:::::::::::::: :.:::.:.:::.: :: ::.::
CCDS77 DSLWDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKI
250 260 270 280 290 300
270 280 290 300 310 320
pF1KE0 RRGQFNIPETLSPKAKCLIRSILRREPSERLTSQEILDHPWFSTDFSVSNSAYGAKEVSD
::: . .: :: :.::.: .:::::.::::. :: :::. : . . .
CCDS77 RRGAYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAA
310 320 330 340 350 360
330 340
pF1KE0 QLVPDVNMEENLDPFFN
:.:::
CCDS77 QVVPDGLGLDEAREEEGDREVVLYG
370 380
343 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 04:38:47 2016 done: Sat Nov 5 04:38:48 2016
Total Scan time: 2.860 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]