Result of FASTA (omim) for
pF1KE0920
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0920, 313 aa
1>>>pF1KE0920 313 - 313 aa - 313 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.7802+/-0.000604; mu= -17.5918+/- 0.035
mean_var=681.5709+/-149.324, 0's: 0 Z-trim(116.6): 962 B-trim: 0 in 0/56
Lambda= 0.049127
statistics sampled from 26611 (27922) to 26611 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.327), width: 16
Scan time: 8.050
The best scores are: opt bits E(85289)
NP_002639 (OMIM: 164960) serine/threonine-protein ( 313) 2158 168.4 1.7e-41
NP_001230115 (OMIM: 164960) serine/threonine-prote ( 404) 2158 168.6 1.9e-41
NP_001001852 (OMIM: 610580) serine/threonine-prote ( 326) 1491 121.2 2.9e-27
NP_006866 (OMIM: 300295) serine/threonine-protein ( 311) 1146 96.7 6.5e-20
NP_112214 (OMIM: 608131) NUAK family SNF1-like kin ( 672) 510 52.1 3.8e-06
NP_055655 (OMIM: 608130) NUAK family SNF1-like kin ( 661) 504 51.6 5e-06
NP_115806 (OMIM: 609235) serine/threonine-protein ( 778) 488 50.6 1.2e-05
XP_011527776 (OMIM: 605705,616341) PREDICTED: seri ( 734) 476 49.7 2.1e-05
NP_056006 (OMIM: 608973) serine/threonine-protein ( 926) 478 50.0 2.2e-05
NP_775490 (OMIM: 605705,616341) serine/threonine-p ( 783) 476 49.8 2.2e-05
XP_005247048 (OMIM: 607505) PREDICTED: PAS domain- (1107) 478 50.1 2.4e-05
NP_003948 (OMIM: 609236) serine/threonine-protein ( 668) 472 49.4 2.4e-05
NP_001243558 (OMIM: 609236) serine/threonine-prote ( 674) 472 49.4 2.4e-05
XP_011509134 (OMIM: 607505) PREDICTED: PAS domain- (1137) 478 50.1 2.5e-05
XP_005253275 (OMIM: 609236) PREDICTED: serine/thre ( 720) 472 49.4 2.5e-05
NP_001243556 (OMIM: 609236) serine/threonine-prote ( 736) 472 49.4 2.6e-05
XP_006718437 (OMIM: 609236) PREDICTED: serine/thre ( 758) 472 49.5 2.6e-05
NP_001239051 (OMIM: 607505) PAS domain-containing (1288) 478 50.2 2.6e-05
XP_016859124 (OMIM: 607505) PREDICTED: PAS domain- (1323) 478 50.2 2.7e-05
NP_001239049 (OMIM: 607505) PAS domain-containing (1323) 478 50.2 2.7e-05
NP_055963 (OMIM: 607505) PAS domain-containing ser (1323) 478 50.2 2.7e-05
XP_016859125 (OMIM: 607505) PREDICTED: PAS domain- (1323) 478 50.2 2.7e-05
XP_016859123 (OMIM: 607505) PREDICTED: PAS domain- (1414) 478 50.3 2.8e-05
XP_016874025 (OMIM: 609236) PREDICTED: serine/thre ( 858) 472 49.5 2.8e-05
XP_016874022 (OMIM: 609236) PREDICTED: serine/thre ( 880) 472 49.6 2.8e-05
XP_011516388 (OMIM: 607025) PREDICTED: maternal em ( 373) 454 47.8 4.2e-05
NP_001156769 (OMIM: 600526) serine/threonine-prote ( 709) 457 48.4 5.2e-05
NP_001156768 (OMIM: 600526) serine/threonine-prote ( 719) 457 48.4 5.3e-05
NP_004945 (OMIM: 600526) serine/threonine-protein ( 724) 457 48.4 5.3e-05
XP_011543100 (OMIM: 600526) PREDICTED: serine/thre ( 729) 457 48.4 5.3e-05
XP_016872800 (OMIM: 600526) PREDICTED: serine/thre ( 738) 457 48.4 5.4e-05
XP_011543099 (OMIM: 600526) PREDICTED: serine/thre ( 739) 457 48.4 5.4e-05
XP_011543098 (OMIM: 600526) PREDICTED: serine/thre ( 744) 457 48.4 5.4e-05
XP_011543097 (OMIM: 600526) PREDICTED: serine/thre ( 745) 457 48.4 5.4e-05
XP_011543096 (OMIM: 600526) PREDICTED: serine/thre ( 753) 457 48.4 5.4e-05
XP_016872799 (OMIM: 600526) PREDICTED: serine/thre ( 763) 457 48.4 5.5e-05
XP_011543095 (OMIM: 600526) PREDICTED: serine/thre ( 784) 457 48.4 5.6e-05
NP_001243614 (OMIM: 607025) maternal embryonic leu ( 610) 454 48.1 5.6e-05
NP_001034558 (OMIM: 600526) serine/threonine-prote ( 788) 457 48.4 5.6e-05
XP_011543094 (OMIM: 600526) PREDICTED: serine/thre ( 793) 457 48.4 5.6e-05
XP_011543093 (OMIM: 600526) PREDICTED: serine/thre ( 798) 457 48.4 5.6e-05
XP_011543092 (OMIM: 600526) PREDICTED: serine/thre ( 799) 457 48.4 5.6e-05
XP_011509137 (OMIM: 607505) PREDICTED: PAS domain- ( 873) 458 48.6 5.6e-05
XP_011516382 (OMIM: 607025) PREDICTED: maternal em ( 622) 454 48.1 5.6e-05
XP_011543091 (OMIM: 600526) PREDICTED: serine/thre ( 808) 457 48.4 5.7e-05
XP_011516379 (OMIM: 607025) PREDICTED: maternal em ( 651) 454 48.1 5.8e-05
NP_055606 (OMIM: 607025) maternal embryonic leucin ( 651) 454 48.1 5.8e-05
XP_011516381 (OMIM: 607025) PREDICTED: maternal em ( 651) 454 48.1 5.8e-05
XP_011516380 (OMIM: 607025) PREDICTED: maternal em ( 651) 454 48.1 5.8e-05
XP_011516378 (OMIM: 607025) PREDICTED: maternal em ( 651) 454 48.1 5.8e-05
>>NP_002639 (OMIM: 164960) serine/threonine-protein kina (313 aa)
initn: 2158 init1: 2158 opt: 2158 Z-score: 866.1 bits: 168.4 E(85289): 1.7e-41
Smith-Waterman score: 2158; 100.0% identity (100.0% similar) in 313 aa overlap (1-313:1-313)
10 20 30 40 50 60
pF1KE0 MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 NLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLIL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 PFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETA
250 260 270 280 290 300
310
pF1KE0 EIHLHSLSPGPSK
:::::::::::::
NP_002 EIHLHSLSPGPSK
310
>>NP_001230115 (OMIM: 164960) serine/threonine-protein k (404 aa)
initn: 2158 init1: 2158 opt: 2158 Z-score: 865.0 bits: 168.6 E(85289): 1.9e-41
Smith-Waterman score: 2158; 100.0% identity (100.0% similar) in 313 aa overlap (1-313:92-404)
10 20 30
pF1KE0 MLLSKINSLAHLRAAPCNDLHATKLAPGKE
::::::::::::::::::::::::::::::
NP_001 PRHSLRHSPGSGSCGSSSGHRPCADILEVGMLLSKINSLAHLRAAPCNDLHATKLAPGKE
70 80 90 100 110 120
40 50 60 70 80 90
pF1KE0 KEPLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEPLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEV
130 140 150 160 170 180
100 110 120 130 140 150
pF1KE0 VLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQ
190 200 210 220 230 240
160 170 180 190 200 210
pF1KE0 VLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPP
250 260 270 280 290 300
220 230 240 250 260 270
pF1KE0 EWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWC
310 320 330 340 350 360
280 290 300 310
pF1KE0 LALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLHSLSPGPSK
:::::::::::::::::::::::::::::::::::::::::::
NP_001 LALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLHSLSPGPSK
370 380 390 400
>>NP_001001852 (OMIM: 610580) serine/threonine-protein k (326 aa)
initn: 1466 init1: 1155 opt: 1491 Z-score: 610.4 bits: 121.2 E(85289): 2.9e-27
Smith-Waterman score: 1491; 69.5% identity (87.3% similar) in 315 aa overlap (1-309:1-313)
10 20 30 40 50
pF1KE0 MLLSKINSLAHLRAAPCNDLHATK-LAPGK-EKEPLESQYQVGPLLGSGGFGSVYSGIRV
:::::..::::: . : .: : :.: .:: .:. :::: .:::::::.::.: :.
NP_001 MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKAYQVGAVLGSGGFGTVYAGSRI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 SDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSS--GFSGVIRLLDWFERPDSF
.:.::::.::: :.:...:: : .:. ::.:::::.::.. : :::::::::::::.:
NP_001 ADGLPVAVKHVVKERVTEWGSL-GGATVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGF
70 80 90 100 110
120 130 140 150 160 170
pF1KE0 VLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILID
.:.::::::.:::::::::::::.: ::: :: ::: ::::::.:::.::::::::.:.:
NP_001 LLVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVD
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 LNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMV
: ::::::::::::::::::::::::::::::::::::::::::::.:::::.::::::
NP_001 LRSGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 CGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWM--QDVL
:::::::.::::.::...::.::: :::.::::::.::::.::....: :::: :
NP_001 CGDIPFEQDEEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWMLGADGG
240 250 260 270 280 290
300 310
pF1KE0 LPQETAEIHLHSLSPGPSK
.: :. ...: .:.:
NP_001 VP-ESCDLRLCTLDPDDVASTTSSSESL
300 310 320
>>NP_006866 (OMIM: 300295) serine/threonine-protein kina (311 aa)
initn: 1143 init1: 907 opt: 1146 Z-score: 478.5 bits: 96.7 E(85289): 6.5e-20
Smith-Waterman score: 1146; 56.3% identity (77.2% similar) in 302 aa overlap (12-311:6-304)
10 20 30 40 50 60
pF1KE0 MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSD
:.. : : ::..: .:..:..:::::.::::.:..: :..:
NP_006 MLTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLGPLLGKGGFGTVFAGHRLTD
10 20 30 40 50
70 80 90 100 110
pF1KE0 NLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSG--FSGVIRLLDWFERPDSFVL
: :::: . ..:. :. : ... :.::.:: ::..: :::::::::: ..:.:
NP_006 RLQVAIKVIPRNRVLGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFML
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 ILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLN
.:::: :.:::::.:::.: : : .: :: ::. :..:::. ::.:::::::::::::
NP_006 VLERPLPAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 RGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCG
:: :::::::::::.: :::::::::::::::: :.::. :.::::::::::::::
NP_006 RGCAKLIDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 DIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQE
:::::.:.::..... : .:: .: ::: ::: .::.::..::: :::: : :
NP_006 DIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQT---PAE
240 250 260 270 280 290
300 310
pF1KE0 TAEIHLHSLSPGPSK
. .. . .:.:
NP_006 DVPLNPSKGGPAPLAWSLLP
300 310
>>NP_112214 (OMIM: 608131) NUAK family SNF1-like kinase (672 aa)
initn: 393 init1: 277 opt: 510 Z-score: 231.4 bits: 52.1 E(85289): 3.8e-06
Smith-Waterman score: 510; 36.0% identity (65.2% similar) in 267 aa overlap (31-290:90-347)
10 20 30 40 50 60
pF1KE0 MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSD
:. :. .:. ::.: .:.: .. . :
NP_112 AAELARPLAEGLIKSPKPLMKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKVKKARESSG
60 70 80 90 100 110
70 80 90 100 110 120
pF1KE0 NLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLIL
: :::: ..::.:.: .: . : :. ...... .: . . :: ...:...
NP_112 RL-VAIKSIRKDKIKDEQDLMHIRR---EIEIMSSLN--HPHIIAIHEVFENSSKIVIVM
120 130 140 150 160 170
130 140 150 160 170 180
pF1KE0 ERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRG
: ::.:.:.:: :.:. :: :: :.. ::..::. :.:::.: ::::.: : :
NP_112 EYASR-GDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDAN-G
180 190 200 210 220 230
190 200 210 220 230
pF1KE0 ELKLIDFGSGALLKDTVYTD-FDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGD
..:. ::: . : .. . . : :. .:. :: . . : : . ::::.::: .: :
NP_112 NIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEVDSWSLGVLLYILVHGT
240 250 260 270 280 290
240 250 260 270 280 290
pF1KE0 IPFE-HDEEIIRGQVF---FRQ--RVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDV
.::. ::..:. :. .:. . :. : :::: : . :. : :.:.. .: :.
NP_112 MPFDGHDHKILVKQISNGAYREPPKPSDACG-LIRWLLMVNPTRRATLEDVASHWWVNWG
300 310 320 330 340 350
300 310
pF1KE0 LLPQETAEIHLHSLSPGPSK
NP_112 YATRVGEQEAPHEGGHPGSDSARASMADWLRRSSRPLLENGAKVCSFFKQHAPGGGSTTP
360 370 380 390 400 410
>>NP_055655 (OMIM: 608130) NUAK family SNF1-like kinase (661 aa)
initn: 418 init1: 256 opt: 504 Z-score: 229.2 bits: 51.6 E(85289): 5e-06
Smith-Waterman score: 504; 35.0% identity (64.7% similar) in 266 aa overlap (31-290:48-306)
10 20 30 40 50 60
pF1KE0 MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSD
:. :. .:.. ::.: .:.: . . .
NP_055 GAPGSPREAVAGATAALEPRKPHGVKRHHHKHNLKHRYELQETLGKGTYGKVKRATERFS
20 30 40 50 60 70
70 80 90 100 110 120
pF1KE0 NLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLIL
. :::: ..::.:.: .. . : :. ...... .: . . :: :..:.:.
NP_055 GRVVAIKSIRKDKIKDEQDMVHIRR---EIEIMSSLN--HPHIISIYEVFENKDKIVIIM
80 90 100 110 120 130
130 140 150 160 170 180
pF1KE0 ERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRG
: .:.:.:.:: :.:. .: :: :.. ::..::. ::.:::.: ::::.: :
NP_055 EYASK-GELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDN-C
140 150 160 170 180 190
190 200 210 220 230
pF1KE0 ELKLIDFGSGALL-KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGD
..:. ::: . : :: : :. .:. :: . . :.: . :.::.::: .: :
NP_055 NIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLVYGT
200 210 220 230 240 250
240 250 260 270 280 290
pF1KE0 IPFE-HDEEIIRGQVF---FRQRVS-SECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVL
.::. :.. . :. .:. .. :. . :::: : . :. : :.:.: :: :.
NP_055 MPFDGFDHKNLIRQISSGEYREPTQPSDARGLIRWMLMVNPDRRATIEDIANHWWVNWGY
260 270 280 290 300 310
300 310
pF1KE0 LPQETAEIHLHSLSPGPSK
NP_055 KSSVCDCDALHDSESPLLARIIDWHHRSTGLQADTEAKMKGLAKPTTSEVMLERQRSLKK
320 330 340 350 360 370
>>NP_115806 (OMIM: 609235) serine/threonine-protein kina (778 aa)
initn: 362 init1: 260 opt: 488 Z-score: 222.3 bits: 50.6 E(85289): 1.2e-05
Smith-Waterman score: 488; 31.8% identity (61.4% similar) in 280 aa overlap (22-289:14-284)
10 20 30 40 50
pF1KE0 MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPL-----LGSGGFGSVYSG
: .: . . : ..:: ::: ::.: : : :
NP_115 MSSGAKEGGGGSPAYHLPHPHPHPPQHAQY-VGPYRLEKTLGKGQTGLVKLG
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 IRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDS
.. . :::: :.....:. . .: :...:: . :..: : .:
NP_115 VHCITGQKVAIKIVNREKLSESVLM----KVEREIAILKLIEHPH--VLKLHDVYENKKY
60 70 80 90 100
120 130 140 150 160 170
pF1KE0 FVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILI
. :.::. .:::.....: : . ::.:: :.. :. ::. .. :::.: ::.:.
NP_115 LYLVLEHVSG-GELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLL
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE0 DLNRGELKLIDFGSGAL-LKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYD
: ....... ::: ..: . :.. :. :. :: :. ..: :: : .:: :..:.
NP_115 D-EKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFA
170 180 190 200 210 220
240 250 260 270 280
pF1KE0 MVCGDIPFEHD------EEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHP
.. : .::. : :.. :: . . . .:: :.: . ..: : ..:.::.::
NP_115 LLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHP
230 240 250 260 270 280
290 300 310
pF1KE0 WMQDVLLPQETAEIHLHSLSPGPSK
:
NP_115 WYLGGKHEPDPCLEPAPGRRVAMRSLPSNGELDPDVLESMASLGCFRDRERLHRELRSEE
290 300 310 320 330 340
>>XP_011527776 (OMIM: 605705,616341) PREDICTED: serine/t (734 aa)
initn: 303 init1: 273 opt: 476 Z-score: 218.0 bits: 49.7 E(85289): 2.1e-05
Smith-Waterman score: 476; 32.7% identity (64.0% similar) in 272 aa overlap (28-291:17-279)
10 20 30 40 50
pF1KE0 MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQ-YQVGPLLGSGGFGSVYSGIRVS
:..: ::. :.. ::.:.:. : . .
XP_011 MVIMSEFSADPAGQGQGQQK-PLRVGFYDIERTLGKGNFAVVKLARHRV
10 20 30 40
60 70 80 90 100 110
pF1KE0 DNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLI
. :::: ..: :... : .. :: :.: .. .:.: . .: : . ..
XP_011 TKTQVAIKIIDKTRLDS----SNLEKIYREVQLMKLLN--HPHIIKLYQVMETKDMLYIV
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE0 LERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNR
: . ..::..: : :.:. ::. :::.: ::..::. ..:::.: ::.:.: :
XP_011 TEFAKN-GEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNM
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE0 GELKLIDFGSGALLKD-TVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCG
..:: ::: : . :. . . :. :. :: .. ..:.: . .::::..:: .:::
XP_011 -DIKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCG
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE0 DIPFEHD------EEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQD
..::. .....:. . .:..:. ::: :.. :. : :. .:..: ::.
XP_011 SLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCESLIRRMLVVDPARRITIAQIRQHRWMRA
230 240 250 260 270 280
300 310
pF1KE0 VLLPQETAEIHLHSLSPGPSK
XP_011 EPCLPGPACPAFSAHSYTSNLGDYDEQALGIMQTLGVDRQRTVEVPQEGLSTDPFRPALL
290 300 310 320 330 340
>>NP_056006 (OMIM: 608973) serine/threonine-protein kina (926 aa)
initn: 364 init1: 265 opt: 478 Z-score: 217.7 bits: 50.0 E(85289): 2.2e-05
Smith-Waterman score: 486; 33.8% identity (62.5% similar) in 275 aa overlap (38-298:20-286)
10 20 30 40 50 60
pF1KE0 SLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIK
:.. ::.:.:. : : . . ::::
NP_056 MVMADGPRHLQRGPVRVGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIK
10 20 30 40
70 80 90 100 110 120
pF1KE0 HVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQ
..:... . : .. :: ..: .. .:.: . .: . . :. : .
NP_056 IIDKSQL----DAVNLEKIYREVQIMKMLD--HPHIIKLYQVMETKSMLYLVTEYAKN-G
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE0 DLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDF
..::.....: :.: :: :::.: :: .::. ..:::.: ::.:.: : ..:. ::
NP_056 EIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLD-NNMNIKIADF
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE0 GSGALLKD-TVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDE
: : ..:. . . . :. :. :: .. ..:.: . .::.:..:: .::: .::.
NP_056 GFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPT
170 180 190 200 210 220
250 260 270 280 290
pF1KE0 -EIIRGQVF---FR--QRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWM-------QDV
:.: .:. :: .: .:.:::: :.: :: : :. .:..: :: . :
NP_056 LPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSKRLTIAQIKEHKWMLIEVPVQRPV
230 240 250 260 270 280
300 310
pF1KE0 LLPQETAEIHLHSLSPGPSK
: :::
NP_056 LYPQEQENEPSIGEFNEQVLRLMHSLGIDQQKTIESLQNKSYNHFAAIYFLLVERLKSHR
290 300 310 320 330 340
>>NP_775490 (OMIM: 605705,616341) serine/threonine-prote (783 aa)
initn: 303 init1: 273 opt: 476 Z-score: 217.7 bits: 49.8 E(85289): 2.2e-05
Smith-Waterman score: 476; 32.7% identity (64.0% similar) in 272 aa overlap (28-291:17-279)
10 20 30 40 50
pF1KE0 MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQ-YQVGPLLGSGGFGSVYSGIRVS
:..: ::. :.. ::.:.:. : . .
NP_775 MVIMSEFSADPAGQGQGQQK-PLRVGFYDIERTLGKGNFAVVKLARHRV
10 20 30 40
60 70 80 90 100 110
pF1KE0 DNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLI
. :::: ..: :... : .. :: :.: .. .:.: . .: : . ..
NP_775 TKTQVAIKIIDKTRLDS----SNLEKIYREVQLMKLLN--HPHIIKLYQVMETKDMLYIV
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE0 LERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNR
: . ..::..: : :.:. ::. :::.: ::..::. ..:::.: ::.:.: :
NP_775 TEFAKN-GEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNM
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE0 GELKLIDFGSGALLKD-TVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCG
..:: ::: : . :. . . :. :. :: .. ..:.: . .::::..:: .:::
NP_775 -DIKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCG
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE0 DIPFEHD------EEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQD
..::. .....:. . .:..:. ::: :.. :. : :. .:..: ::.
NP_775 SLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCESLIRRMLVVDPARRITIAQIRQHRWMRA
230 240 250 260 270 280
300 310
pF1KE0 VLLPQETAEIHLHSLSPGPSK
NP_775 EPCLPGPACPAFSAHSYTSNLGDYDEQALGIMQTLGVDRQRTVESLQNSSYNHFAAIYYL
290 300 310 320 330 340
313 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 04:30:47 2016 done: Sat Nov 5 04:30:48 2016
Total Scan time: 8.050 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]