Result of FASTA (omim) for
pF1KE0911
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0911, 239 aa
1>>>pF1KE0911 239 - 239 aa - 239 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2092+/-0.000358; mu= 14.2753+/- 0.022
mean_var=59.0556+/-12.260, 0's: 0 Z-trim(113.3): 17 B-trim: 915 in 1/52
Lambda= 0.166895
statistics sampled from 22605 (22622) to 22605 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.265), width: 16
Scan time: 6.320
The best scores are: opt bits E(85289)
NP_071356 (OMIM: 606426) egl nine homolog 3 isofor ( 239) 1663 408.7 4.7e-114
NP_071334 (OMIM: 606425,609070,609820) egl nine ho ( 426) 1043 259.5 6.7e-69
NP_444274 (OMIM: 606424) egl nine homolog 2 [Homo ( 407) 1002 249.6 6e-66
NP_542770 (OMIM: 606424) egl nine homolog 2 [Homo ( 407) 1002 249.6 6e-66
XP_005273223 (OMIM: 606425,609070,609820) PREDICTE ( 383) 936 233.7 3.5e-61
NP_001295032 (OMIM: 606426) egl nine homolog 3 iso ( 145) 850 212.8 2.6e-55
XP_005273224 (OMIM: 606425,609070,609820) PREDICTE ( 345) 665 168.4 1.4e-41
>>NP_071356 (OMIM: 606426) egl nine homolog 3 isoform 1 (239 aa)
initn: 1663 init1: 1663 opt: 1663 Z-score: 2168.7 bits: 408.7 E(85289): 4.7e-114
Smith-Waterman score: 1663; 100.0% identity (100.0% similar) in 239 aa overlap (1-239:1-239)
10 20 30 40 50 60
pF1KE0 MPLGHIMRLDLEKIALEYIVPCLHEVGFCYLDNFLGEVVGDCVLERVKQLHCTGALRDGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MPLGHIMRLDLEKIALEYIVPCLHEVGFCYLDNFLGEVVGDCVLERVKQLHCTGALRDGQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 LAGPRAGVSKRHLRGDQITWIGGNEEGCEAISFLLSLIDRLVLYCGSRLGKYYVKERSKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 LAGPRAGVSKRHLRGDQITWIGGNEEGCEAISFLLSLIDRLVLYCGSRLGKYYVKERSKA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 MVACYPGNGTGYVRHVDNPNGDGRCITCIYYLNKNWDAKLHGGILRIFPEGKSFIADVEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MVACYPGNGTGYVRHVDNPNGDGRCITCIYYLNKNWDAKLHGGILRIFPEGKSFIADVEP
130 140 150 160 170 180
190 200 210 220 230
pF1KE0 IFDRLLFFWSDRRNPHEVQPSYATRYAMTVWYFDAEERAEAKKKFRNLTRKTESALTED
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 IFDRLLFFWSDRRNPHEVQPSYATRYAMTVWYFDAEERAEAKKKFRNLTRKTESALTED
190 200 210 220 230
>>NP_071334 (OMIM: 606425,609070,609820) egl nine homolo (426 aa)
initn: 1032 init1: 854 opt: 1043 Z-score: 1358.0 bits: 259.5 E(85289): 6.7e-69
Smith-Waterman score: 1043; 64.3% identity (85.7% similar) in 224 aa overlap (2-225:181-403)
10 20 30
pF1KE0 MPLGHIMRLDLEKIALEYIVPCLHEVGFCYL
: :. : :.::::::::... :.: .
NP_071 ARSSLFQEKANLYPPSNTPGDALSPGGGLRPNGQTKPLPALKLALEYIVPCMNKHGICVV
160 170 180 190 200 210
40 50 60 70 80 90
pF1KE0 DNFLGEVVGDCVLERVKQLHCTGALRDGQLAGPRAGVSKRHLRGDQITWIGGNEEGCEAI
:.:::. .:. . ..:. :: :: . ::::.. .. :: .:::.:::: :.: :::.:
NP_071 DDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSK-DIRGDKITWIEGKEPGCETI
220 230 240 250 260
100 110 120 130 140 150
pF1KE0 SFLLSLIDRLVLYCGSRLGKYYVKERSKAMVACYPGNGTGYVRHVDNPNGDGRCITCIYY
..:.: .: :. .:...::.: .. :.:::::::::::::::::::::::::::.:::::
NP_071 GLLMSSMDDLIRHCNGKLGSYKINGRTKAMVACYPGNGTGYVRHVDNPNGDGRCVTCIYY
270 280 290 300 310 320
160 170 180 190 200 210
pF1KE0 LNKNWDAKLHGGILRIFPEGKSFIADVEPIFDRLLFFWSDRRNPHEVQPSYATRYAMTVW
:::.::::. :::::::::::. .::.:: :::::::::::::::::::.::::::.:::
NP_071 LNKDWDAKVSGGILRIFPEGKAQFADIEPKFDRLLFFWSDRRNPHEVQPAYATRYAITVW
330 340 350 360 370 380
220 230
pF1KE0 YFDAEERAEAKKKFRNLTRKTESALTED
::::.:::.:: :.
NP_071 YFDADERARAKVKYLTGEKGVRVELNKPSDSVGKDVF
390 400 410 420
>>NP_444274 (OMIM: 606424) egl nine homolog 2 [Homo sapi (407 aa)
initn: 1025 init1: 820 opt: 1002 Z-score: 1304.9 bits: 249.6 E(85289): 6e-66
Smith-Waterman score: 1002; 61.9% identity (86.0% similar) in 215 aa overlap (12-226:175-388)
10 20 30 40
pF1KE0 MPLGHIMRLDLEKIALEYIVPCLHEVGFCYLDNFLGEVVGD
:..::.:::::.. :.: :.::: ..:
NP_444 EREGGMSCSCSSGSGEASAGLMEEALPSAPERLALDYIVPCMRYYGICVKDSFLGAALGG
150 160 170 180 190 200
50 60 70 80 90 100
pF1KE0 CVLERVKQLHCTGALRDGQLAGPRAGVSKRHLRGDQITWIGGNEEGCEAISFLLSLIDRL
:: .:. :. : ::::::.. :: . : .:::::.:. :.: ::..:. :.. .: .
NP_444 RVLAEVEALKRGGRLRDGQLVSQRA-IPPRSIRGDQIAWVEGHEPGCRSIGALMAHVDAV
210 220 230 240 250 260
110 120 130 140 150 160
pF1KE0 VLYCGSRLGKYYVKERSKAMVACYPGNGTGYVRHVDNPNGDGRCITCIYYLNKNWDAKLH
. .:..:::.: .. :.::::::::::: :::::::::.:::::::::::::.:::.:.:
NP_444 IRHCAGRLGSYVINGRTKAMVACYPGNGLGYVRHVDNPHGDGRCITCIYYLNQNWDVKVH
270 280 290 300 310 320
170 180 190 200 210 220
pF1KE0 GGILRIFPEGKSFIADVEPIFDRLLFFWSDRRNPHEVQPSYATRYAMTVWYFDAEERAEA
::.:.:::::. .:..::.:::::.:::::::::::.:.::::::.:::::::.::: :
NP_444 GGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEVKPAYATRYAITVWYFDAKERAAA
330 340 350 360 370 380
230
pF1KE0 KKKFRNLTRKTESALTED
: :..
NP_444 KDKYQLASGQKGVQVPVSQPPTPT
390 400
>>NP_542770 (OMIM: 606424) egl nine homolog 2 [Homo sapi (407 aa)
initn: 1025 init1: 820 opt: 1002 Z-score: 1304.9 bits: 249.6 E(85289): 6e-66
Smith-Waterman score: 1002; 61.9% identity (86.0% similar) in 215 aa overlap (12-226:175-388)
10 20 30 40
pF1KE0 MPLGHIMRLDLEKIALEYIVPCLHEVGFCYLDNFLGEVVGD
:..::.:::::.. :.: :.::: ..:
NP_542 EREGGMSCSCSSGSGEASAGLMEEALPSAPERLALDYIVPCMRYYGICVKDSFLGAALGG
150 160 170 180 190 200
50 60 70 80 90 100
pF1KE0 CVLERVKQLHCTGALRDGQLAGPRAGVSKRHLRGDQITWIGGNEEGCEAISFLLSLIDRL
:: .:. :. : ::::::.. :: . : .:::::.:. :.: ::..:. :.. .: .
NP_542 RVLAEVEALKRGGRLRDGQLVSQRA-IPPRSIRGDQIAWVEGHEPGCRSIGALMAHVDAV
210 220 230 240 250 260
110 120 130 140 150 160
pF1KE0 VLYCGSRLGKYYVKERSKAMVACYPGNGTGYVRHVDNPNGDGRCITCIYYLNKNWDAKLH
. .:..:::.: .. :.::::::::::: :::::::::.:::::::::::::.:::.:.:
NP_542 IRHCAGRLGSYVINGRTKAMVACYPGNGLGYVRHVDNPHGDGRCITCIYYLNQNWDVKVH
270 280 290 300 310 320
170 180 190 200 210 220
pF1KE0 GGILRIFPEGKSFIADVEPIFDRLLFFWSDRRNPHEVQPSYATRYAMTVWYFDAEERAEA
::.:.:::::. .:..::.:::::.:::::::::::.:.::::::.:::::::.::: :
NP_542 GGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEVKPAYATRYAITVWYFDAKERAAA
330 340 350 360 370 380
230
pF1KE0 KKKFRNLTRKTESALTED
: :..
NP_542 KDKYQLASGQKGVQVPVSQPPTPT
390 400
>>XP_005273223 (OMIM: 606425,609070,609820) PREDICTED: e (383 aa)
initn: 756 init1: 756 opt: 936 Z-score: 1219.4 bits: 233.7 E(85289): 3.5e-61
Smith-Waterman score: 936; 63.2% identity (84.8% similar) in 204 aa overlap (2-205:181-383)
10 20 30
pF1KE0 MPLGHIMRLDLEKIALEYIVPCLHEVGFCYL
: :. : :.::::::::... :.: .
XP_005 ARSSLFQEKANLYPPSNTPGDALSPGGGLRPNGQTKPLPALKLALEYIVPCMNKHGICVV
160 170 180 190 200 210
40 50 60 70 80 90
pF1KE0 DNFLGEVVGDCVLERVKQLHCTGALRDGQLAGPRAGVSKRHLRGDQITWIGGNEEGCEAI
:.:::. .:. . ..:. :: :: . ::::.. .. :: .:::.:::: :.: :::.:
XP_005 DDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSK-DIRGDKITWIEGKEPGCETI
220 230 240 250 260
100 110 120 130 140 150
pF1KE0 SFLLSLIDRLVLYCGSRLGKYYVKERSKAMVACYPGNGTGYVRHVDNPNGDGRCITCIYY
..:.: .: :. .:...::.: .. :.:::::::::::::::::::::::::::.:::::
XP_005 GLLMSSMDDLIRHCNGKLGSYKINGRTKAMVACYPGNGTGYVRHVDNPNGDGRCVTCIYY
270 280 290 300 310 320
160 170 180 190 200 210
pF1KE0 LNKNWDAKLHGGILRIFPEGKSFIADVEPIFDRLLFFWSDRRNPHEVQPSYATRYAMTVW
:::.::::. :::::::::::. .::.:: :::::::::::::::::::.::::
XP_005 LNKDWDAKVSGGILRIFPEGKAQFADIEPKFDRLLFFWSDRRNPHEVQPAYATR
330 340 350 360 370 380
220 230
pF1KE0 YFDAEERAEAKKKFRNLTRKTESALTED
>>NP_001295032 (OMIM: 606426) egl nine homolog 3 isoform (145 aa)
initn: 845 init1: 845 opt: 850 Z-score: 1114.1 bits: 212.8 E(85289): 2.6e-55
Smith-Waterman score: 850; 94.6% identity (96.1% similar) in 129 aa overlap (111-239:17-145)
90 100 110 120 130 140
pF1KE0 IGGNEEGCEAISFLLSLIDRLVLYCGSRLGKYYVKERSKAMVACYPGNGTGYVRHVDNPN
.: : .:::::::::::::::::::::
NP_001 MPLGHIMRLDLEKIALEYIVPCLHEAMVACYPGNGTGYVRHVDNPN
10 20 30 40
150 160 170 180 190 200
pF1KE0 GDGRCITCIYYLNKNWDAKLHGGILRIFPEGKSFIADVEPIFDRLLFFWSDRRNPHEVQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDGRCITCIYYLNKNWDAKLHGGILRIFPEGKSFIADVEPIFDRLLFFWSDRRNPHEVQP
50 60 70 80 90 100
210 220 230
pF1KE0 SYATRYAMTVWYFDAEERAEAKKKFRNLTRKTESALTED
:::::::::::::::::::::::::::::::::::::::
NP_001 SYATRYAMTVWYFDAEERAEAKKKFRNLTRKTESALTED
110 120 130 140
>>XP_005273224 (OMIM: 606425,609070,609820) PREDICTED: e (345 aa)
initn: 654 init1: 476 opt: 665 Z-score: 867.5 bits: 168.4 E(85289): 1.4e-41
Smith-Waterman score: 665; 56.1% identity (82.3% similar) in 164 aa overlap (2-165:181-343)
10 20 30
pF1KE0 MPLGHIMRLDLEKIALEYIVPCLHEVGFCYL
: :. : :.::::::::... :.: .
XP_005 ARSSLFQEKANLYPPSNTPGDALSPGGGLRPNGQTKPLPALKLALEYIVPCMNKHGICVV
160 170 180 190 200 210
40 50 60 70 80 90
pF1KE0 DNFLGEVVGDCVLERVKQLHCTGALRDGQLAGPRAGVSKRHLRGDQITWIGGNEEGCEAI
:.:::. .:. . ..:. :: :: . ::::.. .. :: .:::.:::: :.: :::.:
XP_005 DDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSK-DIRGDKITWIEGKEPGCETI
220 230 240 250 260
100 110 120 130 140 150
pF1KE0 SFLLSLIDRLVLYCGSRLGKYYVKERSKAMVACYPGNGTGYVRHVDNPNGDGRCITCIYY
..:.: .: :. .:...::.: .. :.:::::::::::::::::::::::::::.:::::
XP_005 GLLMSSMDDLIRHCNGKLGSYKINGRTKAMVACYPGNGTGYVRHVDNPNGDGRCVTCIYY
270 280 290 300 310 320
160 170 180 190 200 210
pF1KE0 LNKNWDAKLHGGILRIFPEGKSFIADVEPIFDRLLFFWSDRRNPHEVQPSYATRYAMTVW
:::.::::.... :
XP_005 LNKDWDAKVRNNCLVF
330 340
239 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 04:27:59 2016 done: Sat Nov 5 04:28:00 2016
Total Scan time: 6.320 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]