Result of FASTA (omim) for
pF1KE0805
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0805, 360 aa
1>>>pF1KE0805 360 - 360 aa - 360 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7543+/-0.00044; mu= 20.2508+/- 0.027
mean_var=107.0731+/-28.658, 0's: 0 Z-trim(111.3): 394 B-trim: 1178 in 1/49
Lambda= 0.123946
statistics sampled from 19233 (19807) to 19233 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.587), E-opt: 0.2 (0.232), width: 16
Scan time: 7.740
The best scores are: opt bits E(85289)
NP_063941 (OMIM: 155540,602025,607948) melanocorti ( 323) 2166 398.6 1e-110
NP_005904 (OMIM: 600042) melanocortin receptor 5 [ ( 325) 1325 248.2 2e-65
NP_005903 (OMIM: 155541,601665) melanocortin recep ( 332) 1273 238.9 1.3e-62
NP_002377 (OMIM: 155555,203200,266300,613098,61309 ( 317) 958 182.5 1.1e-45
NP_000520 (OMIM: 202200,607397) adrenocorticotropi ( 297) 583 115.4 1.6e-25
XP_016881270 (OMIM: 202200,607397) PREDICTED: adre ( 297) 583 115.4 1.6e-25
NP_001278840 (OMIM: 202200,607397) adrenocorticotr ( 297) 583 115.4 1.6e-25
NP_004221 (OMIM: 605111,610419,610419) sphingosine ( 353) 384 80.0 9.3e-15
NP_001391 (OMIM: 601974) sphingosine 1-phosphate r ( 382) 379 79.1 1.8e-14
NP_001307659 (OMIM: 601974) sphingosine 1-phosphat ( 382) 379 79.1 1.8e-14
XP_016882957 (OMIM: 605110) PREDICTED: lysophospha ( 351) 369 77.3 5.9e-14
NP_004711 (OMIM: 605110) lysophosphatidic acid rec ( 351) 369 77.3 5.9e-14
XP_011526723 (OMIM: 605110) PREDICTED: lysophospha ( 351) 369 77.3 5.9e-14
XP_016882958 (OMIM: 605110) PREDICTED: lysophospha ( 351) 369 77.3 5.9e-14
NP_036284 (OMIM: 605106) lysophosphatidic acid rec ( 353) 367 76.9 7.6e-14
NP_005217 (OMIM: 601965) sphingosine 1-phosphate r ( 378) 365 76.6 1e-13
NP_005275 (OMIM: 600553) G-protein coupled recepto ( 362) 333 70.8 5.2e-12
XP_016869881 (OMIM: 602282) PREDICTED: lysophospha ( 364) 333 70.9 5.3e-12
XP_016869894 (OMIM: 602282) PREDICTED: lysophospha ( 364) 333 70.9 5.3e-12
XP_016869887 (OMIM: 602282) PREDICTED: lysophospha ( 364) 333 70.9 5.3e-12
XP_016869886 (OMIM: 602282) PREDICTED: lysophospha ( 364) 333 70.9 5.3e-12
XP_016869893 (OMIM: 602282) PREDICTED: lysophospha ( 364) 333 70.9 5.3e-12
XP_016869895 (OMIM: 602282) PREDICTED: lysophospha ( 364) 333 70.9 5.3e-12
XP_016869880 (OMIM: 602282) PREDICTED: lysophospha ( 364) 333 70.9 5.3e-12
XP_016869883 (OMIM: 602282) PREDICTED: lysophospha ( 364) 333 70.9 5.3e-12
XP_016869885 (OMIM: 602282) PREDICTED: lysophospha ( 364) 333 70.9 5.3e-12
XP_016869884 (OMIM: 602282) PREDICTED: lysophospha ( 364) 333 70.9 5.3e-12
XP_016869892 (OMIM: 602282) PREDICTED: lysophospha ( 364) 333 70.9 5.3e-12
XP_016869874 (OMIM: 602282) PREDICTED: lysophospha ( 364) 333 70.9 5.3e-12
NP_476500 (OMIM: 602282) lysophosphatidic acid rec ( 364) 333 70.9 5.3e-12
XP_016869891 (OMIM: 602282) PREDICTED: lysophospha ( 364) 333 70.9 5.3e-12
XP_005251839 (OMIM: 602282) PREDICTED: lysophospha ( 364) 333 70.9 5.3e-12
XP_016869872 (OMIM: 602282) PREDICTED: lysophospha ( 364) 333 70.9 5.3e-12
XP_016869878 (OMIM: 602282) PREDICTED: lysophospha ( 364) 333 70.9 5.3e-12
XP_005251838 (OMIM: 602282) PREDICTED: lysophospha ( 364) 333 70.9 5.3e-12
XP_016869876 (OMIM: 602282) PREDICTED: lysophospha ( 364) 333 70.9 5.3e-12
XP_016869877 (OMIM: 602282) PREDICTED: lysophospha ( 364) 333 70.9 5.3e-12
XP_016869896 (OMIM: 602282) PREDICTED: lysophospha ( 364) 333 70.9 5.3e-12
XP_016869873 (OMIM: 602282) PREDICTED: lysophospha ( 364) 333 70.9 5.3e-12
XP_016869882 (OMIM: 602282) PREDICTED: lysophospha ( 364) 333 70.9 5.3e-12
XP_016869875 (OMIM: 602282) PREDICTED: lysophospha ( 364) 333 70.9 5.3e-12
XP_016869888 (OMIM: 602282) PREDICTED: lysophospha ( 364) 333 70.9 5.3e-12
NP_001392 (OMIM: 602282) lysophosphatidic acid rec ( 364) 333 70.9 5.3e-12
XP_016869889 (OMIM: 602282) PREDICTED: lysophospha ( 364) 333 70.9 5.3e-12
XP_016869879 (OMIM: 602282) PREDICTED: lysophospha ( 364) 333 70.9 5.3e-12
XP_016869890 (OMIM: 602282) PREDICTED: lysophospha ( 364) 333 70.9 5.3e-12
NP_001273028 (OMIM: 600553) G-protein coupled rece ( 377) 333 70.9 5.4e-12
NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369) 269 59.4 1.5e-08
NP_005279 (OMIM: 600752) G-protein coupled recepto ( 334) 252 56.3 1.1e-07
NP_110387 (OMIM: 605146) sphingosine 1-phosphate r ( 398) 250 56.1 1.6e-07
>>NP_063941 (OMIM: 155540,602025,607948) melanocortin re (323 aa)
initn: 2166 init1: 2166 opt: 2166 Z-score: 2108.5 bits: 398.6 E(85289): 1e-110
Smith-Waterman score: 2166; 100.0% identity (100.0% similar) in 323 aa overlap (38-360:1-323)
10 20 30 40 50 60
pF1KE0 LEGDFVFPVSSSSFLRTLLEPQLGSALLTAMNASCCLPSVQPTLPNGSEHLQAPFFSNQS
::::::::::::::::::::::::::::::
NP_063 MNASCCLPSVQPTLPNGSEHLQAPFFSNQS
10 20 30
70 80 90 100 110 120
pF1KE0 SSAFCEQVFIKPEVFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_063 SSAFCEQVFIKPEVFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVS
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE0 NALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_063 NALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYAL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE0 RYHSIMTVRKALTLIVAIWVCCGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_063 RYHSIMTVRKALTLIVAIWVCCGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHM
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE0 FLFARLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_063 FLFARLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPT
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE0 NPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILCGCNGMNLG
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_063 NPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILCGCNGMNLG
280 290 300 310 320
>>NP_005904 (OMIM: 600042) melanocortin receptor 5 [Homo (325 aa)
initn: 1280 init1: 891 opt: 1325 Z-score: 1295.7 bits: 248.2 E(85289): 2e-65
Smith-Waterman score: 1325; 61.6% identity (85.1% similar) in 323 aa overlap (38-359:1-317)
10 20 30 40 50 60
pF1KE0 LEGDFVFPVSSSSFLRTLLEPQLGSALLTAMNASCCLPSVQPTLPNGSE-HLQAPFFSNQ
::.: : .. .: :..: .:..: .:.
NP_005 MNSSFHLHFLDLNL-NATEGNLSGPNVKNK
10 20
70 80 90 100 110 120
pF1KE0 SSSAFCEQVFIKPEVFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSV
:: ::.. : ::::.::..::::::::: :.:.: :::::::::.:::::::::::.
NP_005 SSP--CEDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSM
30 40 50 60 70 80
130 140 150 160 170 180
pF1KE0 SNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYA
:.: ::: : .... .:.. : :..:.::.::::::::.:::.:.:::::::::::::::
NP_005 SSAWETITIYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYA
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE0 LRYHSIMTVRKALTLIVAIWVCCGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVH
:::: :::.:.. ..:..::. : ::.:::.:::: .::.:::.:::::..:. .::.:
NP_005 LRYHHIMTARRSGAIIAGIWAFCTGCGIVFILYSESTYVILCLISMFFAMLFLLVSLYIH
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE0 MFLFARLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCP
:::.:: ::::::::: :. . .:.. :.::::.:.::::: :::::::::.:...::
NP_005 MFLLARTHVKRIAALPGAS--SARQRTSMQGAVTVTMLLGVFTVCWAPFFLHLTLMLSCP
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE0 TNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILCGCNGMNLG
: :: . .::: ::.:::::::.::::::::: :.:.::.::.: : :. .
NP_005 QNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIIC-CRGFRIACSFPRR
270 280 290 300 310 320
NP_005 D
>>NP_005903 (OMIM: 155541,601665) melanocortin receptor (332 aa)
initn: 1267 init1: 514 opt: 1273 Z-score: 1245.4 bits: 238.9 E(85289): 1.3e-62
Smith-Waterman score: 1273; 61.4% identity (85.5% similar) in 303 aa overlap (53-354:26-319)
30 40 50 60 70 80
pF1KE0 RTLLEPQLGSALLTAMNASCCLPSVQPTLPNGSEHLQAPFFSNQSSSAFC-EQVFIKPEV
:.:: : . :.. : ::.:..:::
NP_005 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGY-----SDGGCYEQLFVSPEV
10 20 30 40 50
90 100 110 120 130 140
pF1KE0 FLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSD
:..::..:::::::::.:...: :::::::::.::::::::::::::. :::.:....:
NP_005 FVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNST
60 70 80 90 100 110
150 160 170 180 190 200
pF1KE0 YLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTL
: ..: ..::..::.:: ::.::::.::.:::::: ::::::.::.::::... .
NP_005 D-TDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGII
120 130 140 150 160
210 220 230 240 250 260
pF1KE0 IVAIWVCCGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAAL
: ::. : : :..::.::.:. ::.:::::::.:. ::..:::::::.::::.::::.:
NP_005 ISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVL
170 180 190 200 210 220
270 280 290 300 310 320
pF1KE0 PPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTY
: . .. .: . ::::.:.:::.:::. :::::::::.. :.:: ::::.:. .::: :
NP_005 PGTGAI--RQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLY
230 240 250 260 270 280
330 340 350 360
pF1KE0 LVLIMCNSVIDPLIYAFRSLELRNTFREILCGCNGMNLG
:.::::::.:::::::.:: :::.::.::.: :
NP_005 LILIMCNSIIDPLIYALRSQELRKTFKEIIC-CYPLGGLCDLSSRY
290 300 310 320 330
>>NP_002377 (OMIM: 155555,203200,266300,613098,613099) m (317 aa)
initn: 940 init1: 584 opt: 958 Z-score: 941.2 bits: 182.5 E(85289): 1.1e-45
Smith-Waterman score: 958; 49.5% identity (77.6% similar) in 295 aa overlap (59-352:23-315)
30 40 50 60 70 80
pF1KE0 QLGSALLTAMNASCCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIV
: . .::.. : : .: :. .:::::.:
NP_002 MAVQGSQRRLLGSLNSTPTAIPQLGLAANQTG-ARCLEVSISDGLFLSLGLV
10 20 30 40 50
90 100 110 120 130 140
pF1KE0 SLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQ
::.:: ::. ....: ::::::: :.: ::..:.::: ::.::: .: .... :. .
NP_002 SLVENALVVATIAKNRNLHSPMYCFICCLALSDLLVSGSNVLETAVILLLEAGALVARAA
60 70 80 90 100 110
150 160 170 180 190 200
pF1KE0 FIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVC
.:..::..: . : :...:.: : :::::::..::::::::::.:. .: ..::::
NP_002 VLQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVA
120 130 140 150 160 170
210 220 230 240 250 260
pF1KE0 CGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVA
: ...::.: . :..::...:.::..::..:::::. : :.. :: : . .
NP_002 SVVFSTLFIAYYDHVAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRPV
180 190 200 210 220 230
270 280 290 300 310 320
pF1KE0 PQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCN
: . .:::::.:::::.:..::.::::::.::. :: .: : : .:: .:.::.::
NP_002 HQGFG-LKGAVTLTILLGIFFLCWGPFFLHLTLIVLCPEHPTCGCIFKNFNLFLALIICN
240 250 260 270 280 290
330 340 350 360
pF1KE0 SVIDPLIYAFRSLELRNTFREIL-CGCNGMNLG
..::::::::.: ::: :..:.: :
NP_002 AIIDPLIYAFHSQELRRTLKEVLTCSW
300 310
>>NP_000520 (OMIM: 202200,607397) adrenocorticotropic ho (297 aa)
initn: 951 init1: 583 opt: 583 Z-score: 579.1 bits: 115.4 E(85289): 1.6e-25
Smith-Waterman score: 940; 47.9% identity (79.8% similar) in 282 aa overlap (72-352:21-293)
50 60 70 80 90 100
pF1KE0 CCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVILAVV
: .: . :.:....::..:::..:.:::
NP_000 MKHIINSYENINNTARNNSDCPRVVLPEEIFFTISIVGVLENLIVLLAVF
10 20 30 40 50
110 120 130 140 150 160
pF1KE0 RNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMI
.: ::..:::::.::::..::: :. . ::.:.: . . :: . .: :.:.::..
NP_000 KNKNLQAPMYFFICSLAISDMLGSLYKILENILIILRNMGYLKPRGSFETTADDIIDSLF
60 70 80 90 100 110
170 180 190 200 210 220
pF1KE0 CISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFIVYSE
.::..:: .: .::.:::.:::.:::::::.:.:........::. : :......:.
NP_000 VLSLLGSIFSLSVIAADRYITIFHALRYHSIVTMRRTVVVLTVIWTFCTGTGITMVIFSH
120 130 140 150 160 170
230 240 250 260 270 280
pF1KE0 SKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVTI
... . ..: :.... :::::::.:: :...:..:: :. ::::.:.
NP_000 HVPTVITFTSLFPLMLVFILCLYVHMFLLARSHTRKISTLPRAN---------MKGAITL
180 190 200 210 220
290 300 310 320 330 340
pF1KE0 TILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSL
:::::::::::::: ::..:. ::.:::: :: . :.. .:::::.::::.::::::
NP_000 TILLGVFIFCWAPFVLHVLLMTFCPSNPYCACYMSLFQVNGMLIMCNAVIDPFIYAFRSP
230 240 250 260 270 280
350 360
pF1KE0 ELRNTFRE-ILCGCNGMNLG
:::..:.. :.:
NP_000 ELRDAFKKMIFCSRYW
290
>>XP_016881270 (OMIM: 202200,607397) PREDICTED: adrenoco (297 aa)
initn: 951 init1: 583 opt: 583 Z-score: 579.1 bits: 115.4 E(85289): 1.6e-25
Smith-Waterman score: 940; 47.9% identity (79.8% similar) in 282 aa overlap (72-352:21-293)
50 60 70 80 90 100
pF1KE0 CCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVILAVV
: .: . :.:....::..:::..:.:::
XP_016 MKHIINSYENINNTARNNSDCPRVVLPEEIFFTISIVGVLENLIVLLAVF
10 20 30 40 50
110 120 130 140 150 160
pF1KE0 RNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMI
.: ::..:::::.::::..::: :. . ::.:.: . . :: . .: :.:.::..
XP_016 KNKNLQAPMYFFICSLAISDMLGSLYKILENILIILRNMGYLKPRGSFETTADDIIDSLF
60 70 80 90 100 110
170 180 190 200 210 220
pF1KE0 CISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFIVYSE
.::..:: .: .::.:::.:::.:::::::.:.:........::. : :......:.
XP_016 VLSLLGSIFSLSVIAADRYITIFHALRYHSIVTMRRTVVVLTVIWTFCTGTGITMVIFSH
120 130 140 150 160 170
230 240 250 260 270 280
pF1KE0 SKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVTI
... . ..: :.... :::::::.:: :...:..:: :. ::::.:.
XP_016 HVPTVITFTSLFPLMLVFILCLYVHMFLLARSHTRKISTLPRAN---------MKGAITL
180 190 200 210 220
290 300 310 320 330 340
pF1KE0 TILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSL
:::::::::::::: ::..:. ::.:::: :: . :.. .:::::.::::.::::::
XP_016 TILLGVFIFCWAPFVLHVLLMTFCPSNPYCACYMSLFQVNGMLIMCNAVIDPFIYAFRSP
230 240 250 260 270 280
350 360
pF1KE0 ELRNTFRE-ILCGCNGMNLG
:::..:.. :.:
XP_016 ELRDAFKKMIFCSRYW
290
>>NP_001278840 (OMIM: 202200,607397) adrenocorticotropic (297 aa)
initn: 951 init1: 583 opt: 583 Z-score: 579.1 bits: 115.4 E(85289): 1.6e-25
Smith-Waterman score: 940; 47.9% identity (79.8% similar) in 282 aa overlap (72-352:21-293)
50 60 70 80 90 100
pF1KE0 CCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVILAVV
: .: . :.:....::..:::..:.:::
NP_001 MKHIINSYENINNTARNNSDCPRVVLPEEIFFTISIVGVLENLIVLLAVF
10 20 30 40 50
110 120 130 140 150 160
pF1KE0 RNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMI
.: ::..:::::.::::..::: :. . ::.:.: . . :: . .: :.:.::..
NP_001 KNKNLQAPMYFFICSLAISDMLGSLYKILENILIILRNMGYLKPRGSFETTADDIIDSLF
60 70 80 90 100 110
170 180 190 200 210 220
pF1KE0 CISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFIVYSE
.::..:: .: .::.:::.:::.:::::::.:.:........::. : :......:.
NP_001 VLSLLGSIFSLSVIAADRYITIFHALRYHSIVTMRRTVVVLTVIWTFCTGTGITMVIFSH
120 130 140 150 160 170
230 240 250 260 270 280
pF1KE0 SKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVTI
... . ..: :.... :::::::.:: :...:..:: :. ::::.:.
NP_001 HVPTVITFTSLFPLMLVFILCLYVHMFLLARSHTRKISTLPRAN---------MKGAITL
180 190 200 210 220
290 300 310 320 330 340
pF1KE0 TILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSL
:::::::::::::: ::..:. ::.:::: :: . :.. .:::::.::::.::::::
NP_001 TILLGVFIFCWAPFVLHVLLMTFCPSNPYCACYMSLFQVNGMLIMCNAVIDPFIYAFRSP
230 240 250 260 270 280
350 360
pF1KE0 ELRNTFRE-ILCGCNGMNLG
:::..:.. :.:
NP_001 ELRDAFKKMIFCSRYW
290
>>NP_004221 (OMIM: 605111,610419,610419) sphingosine 1-p (353 aa)
initn: 355 init1: 135 opt: 384 Z-score: 386.0 bits: 80.0 E(85289): 9.3e-15
Smith-Waterman score: 430; 32.7% identity (61.2% similar) in 327 aa overlap (52-359:11-312)
30 40 50 60 70 80
pF1KE0 LRTLLEPQLGSALLTAMNASCCLPSVQPTLPNG-SEHLQAPFFSNQSSSAFCEQVFIKPE
:: .:: . . ... . .::
NP_004 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFI
10 20 30 40
90 100 110 120 130 140
pF1KE0 VFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHS
:.: .:: .::.::..::.::...:: ::.:: .::..:.:..:. . .:.. . : .
NP_004 VILCCAIV--VENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSV-T
50 60 70 80 90
150 160 170 180 190 200
pF1KE0 DYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALT
:: :.. . . : :.: ::. .:::::..:.:.: . : : . : :
NP_004 LRLT-PVQWFAREGSAF-----ITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCR-MLL
100 110 120 130 140 150
210 220 230 240
pF1KE0 LIVAIWV--------------CCG---VCGVVFIVYSESKMVIVCLITMFFAMMLLMGTL
:: : :. : : .:..:. .: .: ..:..:.: ..: . .:
NP_004 LIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLY--AKHYVLCVVTIFSIILLAIVAL
160 170 180 190 200
250 260 270 280 290 300
pF1KE0 YVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLII
::... .: :: .::: . .: :.::.::::: :: : : :.:
NP_004 YVRIYCVVRSS--------HADMAAPQTLALLK---TVTIVLGVFIVCWLPAFSILLLDY
210 220 230 240 250
310 320 330 340 350 360
pF1KE0 TCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELR-NTFREILCGCNGMNLG
.::.. : : ::. .... ::...:.::..:: .:: ...: . : :...
NP_004 ACPVHSCPILYKAHY--FFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGR
260 270 280 290 300 310
NP_004 RRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
320 330 340 350
>>NP_001391 (OMIM: 601974) sphingosine 1-phosphate recep (382 aa)
initn: 324 init1: 126 opt: 379 Z-score: 380.8 bits: 79.1 E(85289): 1.8e-14
Smith-Waterman score: 391; 28.0% identity (63.1% similar) in 293 aa overlap (81-354:51-331)
60 70 80 90 100 110
pF1KE0 LPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVILAVVRNGNLHSPM
::. . .::::.:.:.. .. ..: ::
NP_001 NYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPM
30 40 50 60 70 80
120 130 140 150 160 170
pF1KE0 YFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASIC
:.:. .::..:.:..:. . ..... . . :: . :... ::. ..: ::.
NP_001 YYFIGNLALSDLLAGVAYT-ANLLLSGATTYKLTPAQWFLRE-----GSMF-VALSASVF
90 100 110 120 130
180 190 200 210
pF1KE0 NLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWV--------------CCGV---CG
.:::::..::.:.. .. :. . . . :: : :: : .. :.
NP_001 SLLAIAIERYITML-KMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCS
140 150 160 170 180 190
220 230 240 250 260 270
pF1KE0 VVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHS
.:. .: . .... : :.: ..: . :: ... ..: . .:.. . .. ....
NP_001 TVLPLYHK-HYILFCT-TVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEK
200 210 220 230 240 250
280 290 300 310 320 330
pF1KE0 CMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDP
. :. :.:.::: ::::.:. :.: . : .. : . :.. .::: . :: .:
NP_001 SLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEY--FLVLAVLNSGTNP
260 270 280 290 300
340 350 360
pF1KE0 LIYAFRSLELRNTFREIL--CGCNGMNLG
.::.. . :.: .: .:. : :
NP_001 IIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDN
310 320 330 340 350 360
>>NP_001307659 (OMIM: 601974) sphingosine 1-phosphate re (382 aa)
initn: 324 init1: 126 opt: 379 Z-score: 380.8 bits: 79.1 E(85289): 1.8e-14
Smith-Waterman score: 391; 28.0% identity (63.1% similar) in 293 aa overlap (81-354:51-331)
60 70 80 90 100 110
pF1KE0 LPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVILAVVRNGNLHSPM
::. . .::::.:.:.. .. ..: ::
NP_001 NYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPM
30 40 50 60 70 80
120 130 140 150 160 170
pF1KE0 YFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASIC
:.:. .::..:.:..:. . ..... . . :: . :... ::. ..: ::.
NP_001 YYFIGNLALSDLLAGVAYT-ANLLLSGATTYKLTPAQWFLRE-----GSMF-VALSASVF
90 100 110 120 130
180 190 200 210
pF1KE0 NLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWV--------------CCGV---CG
.:::::..::.:.. .. :. . . . :: : :: : .. :.
NP_001 SLLAIAIERYITML-KMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCS
140 150 160 170 180 190
220 230 240 250 260 270
pF1KE0 VVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHS
.:. .: . .... : :.: ..: . :: ... ..: . .:.. . .. ....
NP_001 TVLPLYHK-HYILFCT-TVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEK
200 210 220 230 240 250
280 290 300 310 320 330
pF1KE0 CMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDP
. :. :.:.::: ::::.:. :.: . : .. : . :.. .::: . :: .:
NP_001 SLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEY--FLVLAVLNSGTNP
260 270 280 290 300
340 350 360
pF1KE0 LIYAFRSLELRNTFREIL--CGCNGMNLG
.::.. . :.: .: .:. : :
NP_001 IIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDN
310 320 330 340 350 360
360 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 03:14:45 2016 done: Sat Nov 5 03:14:46 2016
Total Scan time: 7.740 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]