Result of FASTA (omim) for
pF1KE0763
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0763, 337 aa
1>>>pF1KE0763 337 - 337 aa - 337 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.2945+/-0.000765; mu= -18.6493+/- 0.044
mean_var=838.8937+/-197.948, 0's: 0 Z-trim(112.3): 101 B-trim: 996 in 1/54
Lambda= 0.044281
statistics sampled from 21087 (21172) to 21087 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.602), E-opt: 0.2 (0.248), width: 16
Scan time: 6.470
The best scores are: opt bits E(85289)
NP_001883 (OMIM: 600505) casein kinase I isoform a ( 337) 2084 149.4 1e-35
NP_001258670 (OMIM: 600505) casein kinase I isofor ( 325) 2037 146.4 8.1e-35
NP_689407 (OMIM: 600863) casein kinase I isoform e ( 416) 1519 113.4 8.5e-25
NP_001885 (OMIM: 600863) casein kinase I isoform e ( 416) 1519 113.4 8.5e-25
NP_620693 (OMIM: 600864,615224) casein kinase I is ( 409) 1517 113.3 9.2e-25
NP_001884 (OMIM: 600864,615224) casein kinase I is ( 415) 1517 113.3 9.3e-25
XP_005256394 (OMIM: 600864,615224) PREDICTED: case ( 427) 1517 113.3 9.4e-25
XP_005256393 (OMIM: 600864,615224) PREDICTED: case ( 450) 1517 113.4 9.7e-25
XP_016879688 (OMIM: 600864,615224) PREDICTED: case ( 393) 1279 98.1 3.4e-20
NP_001258671 (OMIM: 600505) casein kinase I isofor ( 276) 1169 90.8 3.7e-18
NP_001020276 (OMIM: 600505) casein kinase I isofor ( 365) 1169 91.0 4.3e-18
XP_005271953 (OMIM: 604253) PREDICTED: casein kina ( 416) 1095 86.3 1.2e-16
XP_005271948 (OMIM: 604253) PREDICTED: casein kina ( 456) 1096 86.5 1.2e-16
XP_016864558 (OMIM: 604253) PREDICTED: casein kina ( 424) 1095 86.4 1.2e-16
NP_001257501 (OMIM: 604253) casein kinase I isofor ( 424) 1095 86.4 1.2e-16
XP_005271952 (OMIM: 604253) PREDICTED: casein kina ( 424) 1095 86.4 1.2e-16
NP_004375 (OMIM: 604253) casein kinase I isoform g ( 447) 1085 85.8 2e-16
XP_005271951 (OMIM: 604253) PREDICTED: casein kina ( 447) 1085 85.8 2e-16
XP_016864559 (OMIM: 604253) PREDICTED: casein kina ( 415) 1084 85.6 2e-16
XP_005271949 (OMIM: 604253) PREDICTED: casein kina ( 455) 1085 85.8 2e-16
NP_001038188 (OMIM: 604253) casein kinase I isofor ( 455) 1085 85.8 2e-16
NP_001026982 (OMIM: 604253) casein kinase I isofor ( 423) 1084 85.7 2e-16
NP_071331 (OMIM: 606274) casein kinase I isoform g ( 422) 1069 84.7 3.9e-16
NP_001316535 (OMIM: 606274) casein kinase I isofor ( 422) 1069 84.7 3.9e-16
NP_001316536 (OMIM: 606274) casein kinase I isofor ( 438) 1069 84.7 3.9e-16
NP_001316534 (OMIM: 606274) casein kinase I isofor ( 475) 1069 84.8 4.1e-16
XP_005259557 (OMIM: 602214) PREDICTED: casein kina ( 440) 1060 84.1 5.9e-16
NP_001310 (OMIM: 602214) casein kinase I isoform g ( 415) 1058 84.0 6.2e-16
XP_016864552 (OMIM: 604253) PREDICTED: casein kina ( 473) 1015 81.3 4.5e-15
XP_016864556 (OMIM: 604253) PREDICTED: casein kina ( 441) 1014 81.2 4.5e-15
XP_016864548 (OMIM: 604253) PREDICTED: casein kina ( 481) 1015 81.3 4.5e-15
XP_016864547 (OMIM: 604253) PREDICTED: casein kina ( 481) 1015 81.3 4.5e-15
XP_016864546 (OMIM: 604253) PREDICTED: casein kina ( 481) 1015 81.3 4.5e-15
XP_016864549 (OMIM: 604253) PREDICTED: casein kina ( 481) 1015 81.3 4.5e-15
XP_016864553 (OMIM: 604253) PREDICTED: casein kina ( 449) 1014 81.2 4.6e-15
XP_016864557 (OMIM: 604253) PREDICTED: casein kina ( 440) 1003 80.5 7.4e-15
XP_016864551 (OMIM: 604253) PREDICTED: casein kina ( 480) 1004 80.6 7.4e-15
XP_016864550 (OMIM: 604253) PREDICTED: casein kina ( 480) 1004 80.6 7.4e-15
XP_016864554 (OMIM: 604253) PREDICTED: casein kina ( 448) 1003 80.5 7.4e-15
XP_016864555 (OMIM: 604253) PREDICTED: casein kina ( 448) 1003 80.5 7.4e-15
XP_005259558 (OMIM: 602214) PREDICTED: casein kina ( 392) 984 79.2 1.6e-14
XP_016881787 (OMIM: 602214) PREDICTED: casein kina ( 367) 982 79.0 1.7e-14
NP_001257502 (OMIM: 604253) casein kinase I isofor ( 348) 967 78.1 3.2e-14
XP_005259555 (OMIM: 602214) PREDICTED: casein kina ( 445) 912 74.7 4.2e-13
XP_016881786 (OMIM: 602214) PREDICTED: casein kina ( 445) 912 74.7 4.2e-13
XP_005259556 (OMIM: 602214) PREDICTED: casein kina ( 445) 912 74.7 4.2e-13
NP_001257503 (OMIM: 604253) casein kinase I isofor ( 311) 897 73.5 6.7e-13
NP_775771 (OMIM: 604432,611695) tau-tubulin kinase (1244) 543 51.8 9.1e-06
XP_006720466 (OMIM: 604432,611695) PREDICTED: tau- (1175) 440 45.2 0.00084
XP_005254230 (OMIM: 604432,611695) PREDICTED: tau- (1175) 440 45.2 0.00084
>>NP_001883 (OMIM: 600505) casein kinase I isoform alpha (337 aa)
initn: 2139 init1: 2075 opt: 2084 Z-score: 762.1 bits: 149.4 E(85289): 1e-35
Smith-Waterman score: 2084; 91.6% identity (97.9% similar) in 335 aa overlap (1-335:1-335)
10 20 30 40 50 60
pF1KE0 MTNNSGSKAELVVGGKYKLVRKIGSGSFGDVYLGITTTNGEEVAVKLESQKVKHPQLLYE
:...::::::..::::::::::::::::::.::.:. ::::::::::::::..:::::::
NP_001 MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 SKLYTILQGGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
:::: ::::::::::..::::::: :::::::::::::::::::::::::::::::::::
NP_001 SKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ISRIEYVHTKNFLHRDIKPDNFLMGTGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKH
::::::::::::.:::::::::::: :::::::::::::::::::::::::::::::::.
NP_001 ISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 LIGTVRYASINAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLKAMTKKQKYEKISEKK
: ::.:::::::::::::::::::::::::.::::::::::::::: :::::::::::::
NP_001 LTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLFRILFRTLNHQYDYTFDWTM
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
NP_001 MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTM
250 260 270 280 290 300
310 320 330
pF1KE0 LKQKAAQQAASSSGQGQQAQTQTGKQTEKNKNNVKDN
::::::::::::::::::::: :::::.:.:.:.:
NP_001 LKQKAAQQAASSSGQGQQAQTPTGKQTDKTKSNMKGF
310 320 330
>>NP_001258670 (OMIM: 600505) casein kinase I isoform al (325 aa)
initn: 2037 init1: 2037 opt: 2037 Z-score: 746.0 bits: 146.4 E(85289): 8.1e-35
Smith-Waterman score: 2037; 92.6% identity (97.8% similar) in 324 aa overlap (1-324:1-324)
10 20 30 40 50 60
pF1KE0 MTNNSGSKAELVVGGKYKLVRKIGSGSFGDVYLGITTTNGEEVAVKLESQKVKHPQLLYE
:...::::::..::::::::::::::::::.::.:. ::::::::::::::..:::::::
NP_001 MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 SKLYTILQGGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
:::: ::::::::::..::::::: :::::::::::::::::::::::::::::::::::
NP_001 SKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ISRIEYVHTKNFLHRDIKPDNFLMGTGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKH
::::::::::::.:::::::::::: :::::::::::::::::::::::::::::::::.
NP_001 ISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 LIGTVRYASINAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLKAMTKKQKYEKISEKK
: ::.:::::::::::::::::::::::::.::::::::::::::: :::::::::::::
NP_001 LTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLFRILFRTLNHQYDYTFDWTM
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
NP_001 MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTM
250 260 270 280 290 300
310 320 330
pF1KE0 LKQKAAQQAASSSGQGQQAQTQTGKQTEKNKNNVKDN
::::::::::::::::::::: ::
NP_001 LKQKAAQQAASSSGQGQQAQTPTGF
310 320
>>NP_689407 (OMIM: 600863) casein kinase I isoform epsil (416 aa)
initn: 1519 init1: 1519 opt: 1519 Z-score: 566.2 bits: 113.4 E(85289): 8.5e-25
Smith-Waterman score: 1519; 72.5% identity (89.6% similar) in 298 aa overlap (10-307:2-299)
10 20 30 40 50 60
pF1KE0 MTNNSGSKAELVVGGKYKLVRKIGSGSFGDVYLGITTTNGEEVAVKLESQKVKHPQLLYE
:: ::.::.: ::::::::::.::: . ..:::::.::: :.::::: :
NP_689 MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIE
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 SKLYTILQGGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
::.: ..::::::: ..: : : : ::.::.:::::::::::::::.:..::::.:::::
NP_689 SKFYKMMQGGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 ISRIEYVHTKNFLHRDIKPDNFLMGTGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKH
::::::.:.:::.:::.:::::::: :.. : ...::::::::::: ::.:::::::.:.
NP_689 ISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 LIGTVRYASINAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLKAMTKKQKYEKISEKK
: ::.::::::.:::::::::::.::::::.:::: ::::::::: ::.::::.:::::
NP_689 LTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKK
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE0 MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLFRILFRTLNHQYDYTFDWTM
::::.::::::.:.::. :::.::.:::.. ::: ::::::: ::. . .:::.:::.:
NP_689 MSTPIEVLCKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNM
240 250 260 270 280 290
310 320 330
pF1KE0 LKQKAAQQAASSSGQGQQAQTQTGKQTEKNKNNVKDN
:: ::.
NP_689 LKFGAARNPEDVDRERREHEREERMGQLRGSATRALPPGPPTGATANRLRSAAEPVASTP
300 310 320 330 340 350
>>NP_001885 (OMIM: 600863) casein kinase I isoform epsil (416 aa)
initn: 1519 init1: 1519 opt: 1519 Z-score: 566.2 bits: 113.4 E(85289): 8.5e-25
Smith-Waterman score: 1519; 72.5% identity (89.6% similar) in 298 aa overlap (10-307:2-299)
10 20 30 40 50 60
pF1KE0 MTNNSGSKAELVVGGKYKLVRKIGSGSFGDVYLGITTTNGEEVAVKLESQKVKHPQLLYE
:: ::.::.: ::::::::::.::: . ..:::::.::: :.::::: :
NP_001 MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIE
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 SKLYTILQGGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
::.: ..::::::: ..: : : : ::.::.:::::::::::::::.:..::::.:::::
NP_001 SKFYKMMQGGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 ISRIEYVHTKNFLHRDIKPDNFLMGTGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKH
::::::.:.:::.:::.:::::::: :.. : ...::::::::::: ::.:::::::.:.
NP_001 ISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 LIGTVRYASINAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLKAMTKKQKYEKISEKK
: ::.::::::.:::::::::::.::::::.:::: ::::::::: ::.::::.:::::
NP_001 LTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKK
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE0 MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLFRILFRTLNHQYDYTFDWTM
::::.::::::.:.::. :::.::.:::.. ::: ::::::: ::. . .:::.:::.:
NP_001 MSTPIEVLCKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNM
240 250 260 270 280 290
310 320 330
pF1KE0 LKQKAAQQAASSSGQGQQAQTQTGKQTEKNKNNVKDN
:: ::.
NP_001 LKFGAARNPEDVDRERREHEREERMGQLRGSATRALPPGPPTGATANRLRSAAEPVASTP
300 310 320 330 340 350
>>NP_620693 (OMIM: 600864,615224) casein kinase I isofor (409 aa)
initn: 1512 init1: 1512 opt: 1517 Z-score: 565.5 bits: 113.3 E(85289): 9.2e-25
Smith-Waterman score: 1517; 72.0% identity (88.7% similar) in 300 aa overlap (10-309:2-301)
10 20 30 40 50 60
pF1KE0 MTNNSGSKAELVVGGKYKLVRKIGSGSFGDVYLGITTTNGEEVAVKLESQKVKHPQLLYE
:: ::..:.: ::::::::::.::: . :::::.::: :.::::: :
NP_620 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIE
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 SKLYTILQGGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
::.: ..::::::: ..: : : : ::.::.:::::::::::::::.:..::::.:::::
NP_620 SKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 ISRIEYVHTKNFLHRDIKPDNFLMGTGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKH
::::::.:.:::.:::.:::::::: :.. : ...::::::::::: ::.:::::::.:.
NP_620 ISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 LIGTVRYASINAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLKAMTKKQKYEKISEKK
: ::.::::::.:::::::::::.::::::.:::: ::::::::: ::.::::.:::::
NP_620 LTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKK
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE0 MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLFRILFRTLNHQYDYTFDWTM
::::.::::::.:.::: :::.::.:::.. ::: ::::::: ::. . .:::.:::.:
NP_620 MSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNM
240 250 260 270 280 290
310 320 330
pF1KE0 LKQKAAQQAASSSGQGQQAQTQTGKQTEKNKNNVKDN
:: :.. :
NP_620 LKFGASRAADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHT
300 310 320 330 340 350
>>NP_001884 (OMIM: 600864,615224) casein kinase I isofor (415 aa)
initn: 1512 init1: 1512 opt: 1517 Z-score: 565.5 bits: 113.3 E(85289): 9.3e-25
Smith-Waterman score: 1517; 72.0% identity (88.7% similar) in 300 aa overlap (10-309:2-301)
10 20 30 40 50 60
pF1KE0 MTNNSGSKAELVVGGKYKLVRKIGSGSFGDVYLGITTTNGEEVAVKLESQKVKHPQLLYE
:: ::..:.: ::::::::::.::: . :::::.::: :.::::: :
NP_001 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIE
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 SKLYTILQGGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
::.: ..::::::: ..: : : : ::.::.:::::::::::::::.:..::::.:::::
NP_001 SKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 ISRIEYVHTKNFLHRDIKPDNFLMGTGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKH
::::::.:.:::.:::.:::::::: :.. : ...::::::::::: ::.:::::::.:.
NP_001 ISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 LIGTVRYASINAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLKAMTKKQKYEKISEKK
: ::.::::::.:::::::::::.::::::.:::: ::::::::: ::.::::.:::::
NP_001 LTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKK
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE0 MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLFRILFRTLNHQYDYTFDWTM
::::.::::::.:.::: :::.::.:::.. ::: ::::::: ::. . .:::.:::.:
NP_001 MSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNM
240 250 260 270 280 290
310 320 330
pF1KE0 LKQKAAQQAASSSGQGQQAQTQTGKQTEKNKNNVKDN
:: :.. :
NP_001 LKFGASRAADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHT
300 310 320 330 340 350
>>XP_005256394 (OMIM: 600864,615224) PREDICTED: casein k (427 aa)
initn: 1512 init1: 1512 opt: 1517 Z-score: 565.4 bits: 113.3 E(85289): 9.4e-25
Smith-Waterman score: 1517; 72.0% identity (88.7% similar) in 300 aa overlap (10-309:2-301)
10 20 30 40 50 60
pF1KE0 MTNNSGSKAELVVGGKYKLVRKIGSGSFGDVYLGITTTNGEEVAVKLESQKVKHPQLLYE
:: ::..:.: ::::::::::.::: . :::::.::: :.::::: :
XP_005 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIE
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 SKLYTILQGGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
::.: ..::::::: ..: : : : ::.::.:::::::::::::::.:..::::.:::::
XP_005 SKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 ISRIEYVHTKNFLHRDIKPDNFLMGTGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKH
::::::.:.:::.:::.:::::::: :.. : ...::::::::::: ::.:::::::.:.
XP_005 ISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 LIGTVRYASINAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLKAMTKKQKYEKISEKK
: ::.::::::.:::::::::::.::::::.:::: ::::::::: ::.::::.:::::
XP_005 LTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKK
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE0 MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLFRILFRTLNHQYDYTFDWTM
::::.::::::.:.::: :::.::.:::.. ::: ::::::: ::. . .:::.:::.:
XP_005 MSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNM
240 250 260 270 280 290
310 320 330
pF1KE0 LKQKAAQQAASSSGQGQQAQTQTGKQTEKNKNNVKDN
:: :.. :
XP_005 LKFGASRAADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHT
300 310 320 330 340 350
>>XP_005256393 (OMIM: 600864,615224) PREDICTED: casein k (450 aa)
initn: 1512 init1: 1512 opt: 1517 Z-score: 565.1 bits: 113.4 E(85289): 9.7e-25
Smith-Waterman score: 1517; 72.0% identity (88.7% similar) in 300 aa overlap (10-309:2-301)
10 20 30 40 50 60
pF1KE0 MTNNSGSKAELVVGGKYKLVRKIGSGSFGDVYLGITTTNGEEVAVKLESQKVKHPQLLYE
:: ::..:.: ::::::::::.::: . :::::.::: :.::::: :
XP_005 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIE
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 SKLYTILQGGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
::.: ..::::::: ..: : : : ::.::.:::::::::::::::.:..::::.:::::
XP_005 SKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 ISRIEYVHTKNFLHRDIKPDNFLMGTGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKH
::::::.:.:::.:::.:::::::: :.. : ...::::::::::: ::.:::::::.:.
XP_005 ISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 LIGTVRYASINAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLKAMTKKQKYEKISEKK
: ::.::::::.:::::::::::.::::::.:::: ::::::::: ::.::::.:::::
XP_005 LTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKK
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE0 MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLFRILFRTLNHQYDYTFDWTM
::::.::::::.:.::: :::.::.:::.. ::: ::::::: ::. . .:::.:::.:
XP_005 MSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNM
240 250 260 270 280 290
310 320 330
pF1KE0 LKQKAAQQAASSSGQGQQAQTQTGKQTEKNKNNVKDN
:: :.. :
XP_005 LKFGASRAADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHT
300 310 320 330 340 350
>>XP_016879688 (OMIM: 600864,615224) PREDICTED: casein k (393 aa)
initn: 1274 init1: 1274 opt: 1279 Z-score: 483.5 bits: 98.1 E(85289): 3.4e-20
Smith-Waterman score: 1279; 73.4% identity (90.6% similar) in 244 aa overlap (66-309:1-244)
40 50 60 70 80 90
pF1KE0 TTTNGEEVAVKLESQKVKHPQLLYESKLYTILQGGVGIPHMHWYGQEKDNNVLVMDLLGP
..::::::: ..: : : : ::.::.::::
XP_016 MMQGGVGIPTIRWCGAEGDYNVMVMELLGP
10 20 30
100 110 120 130 140 150
pF1KE0 SLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFLHRDIKPDNFLMGTGRHCNKLFL
:::::::::::.:..::::.:::::::::::.:.:::.:::.:::::::: :.. : ...
XP_016 SLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYI
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE0 IDFGLAKKYRDNRTRQHIPYREDKHLIGTVRYASINAHLGIEQSRRDDMESLGYVFMYFN
::::::::::: ::.:::::::.:.: ::.::::::.:::::::::::.::::::.::::
XP_016 IDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFN
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE0 RTSLPWQGLKAMTKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEVPDYM
::::::::: ::.::::.:::::::::.::::::.:.::: :::.::.:::.. :::
XP_016 LGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYS
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE0 YLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAASSSGQGQQAQTQTGKQTEKNKNNVK
::::::: ::. . .:::.:::.::: :.. :
XP_016 YLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERRDREERLRHSRNPATRGLP
220 230 240 250 260 270
pF1KE0 DN
XP_016 STASGRLRGTQEVAPPTPLTPTSHTANTSPRPVSGMERERKVSMRLHRGAPVNISSSDLT
280 290 300 310 320 330
>>NP_001258671 (OMIM: 600505) casein kinase I isoform al (276 aa)
initn: 1640 init1: 1160 opt: 1169 Z-score: 447.1 bits: 90.8 E(85289): 3.7e-18
Smith-Waterman score: 1519; 85.0% identity (88.3% similar) in 274 aa overlap (90-335:1-274)
60 70 80 90 100 110
pF1KE0 ESKLYTILQGGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQ
::::::::::::::::::::::::::::::
NP_001 MDLLGPSLEDLFNFCSRRFTMKTVLMLADQ
10 20 30
120 130 140 150
pF1KE0 MISRIEYVHTKNFLHRDIKPDNFLMGTGRHCNK---------------------------
:::::::::::::.:::::::::::: ::::::
NP_001 MISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKCLESPVGKRKRSMTVSTSQDPSFSGLN
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE0 -LFLIDFGLAKKYRDNRTRQHIPYREDKHLIGTVRYASINAHLGIEQSRRDDMESLGYVF
:::::::::::::::::::::::::::.: ::.:::::::::::::::::::::::::.
NP_001 QLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVL
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE0 MYFNRTSLPWQGLKAMTKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEV
::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::.
NP_001 MYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEA
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE0 PDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAASSSGQGQQAQTQTGKQTEKNK
:::::::::::::::::::::::::::::::::::::::::::::::::: :::::.:.:
NP_001 PDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAASSSGQGQQAQTPTGKQTDKTK
220 230 240 250 260 270
pF1KE0 NNVKDN
.:.:
NP_001 SNMKGF
337 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 08:11:43 2016 done: Sat Nov 5 08:11:44 2016
Total Scan time: 6.470 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]