Result of FASTA (omim) for
pF1KE0738
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0738, 424 aa
1>>>pF1KE0738 424 - 424 aa - 424 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0223+/-0.000341; mu= 19.4940+/- 0.021
mean_var=104.9378+/-25.580, 0's: 0 Z-trim(116.2): 527 B-trim: 2879 in 2/48
Lambda= 0.125201
statistics sampled from 26407 (27157) to 26407 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.673), E-opt: 0.2 (0.318), width: 16
Scan time: 9.370
The best scores are: opt bits E(85289)
NP_000698 (OMIM: 600264) vasopressin V1b receptor ( 424) 2883 531.7 1.4e-150
NP_000697 (OMIM: 600821) vasopressin V1a receptor ( 418) 1252 237.1 6.5e-62
NP_000907 (OMIM: 167055) oxytocin receptor [Homo s ( 389) 812 157.6 5.2e-38
XP_011532064 (OMIM: 167055) PREDICTED: oxytocin re ( 389) 812 157.6 5.2e-38
NP_001139623 (OMIM: 300538,300539,304800) vasopres ( 309) 668 131.4 3.1e-30
NP_000045 (OMIM: 300538,300539,304800) vasopressin ( 371) 668 131.5 3.4e-30
XP_006724891 (OMIM: 300538,300539,304800) PREDICTE ( 371) 668 131.5 3.4e-30
NP_997055 (OMIM: 608584,608595) neuropeptide S rec ( 371) 415 85.8 2e-16
NP_997056 (OMIM: 608584,608595) neuropeptide S rec ( 377) 415 85.8 2e-16
NP_001287864 (OMIM: 608584,608595) neuropeptide S ( 390) 415 85.8 2e-16
NP_001517 (OMIM: 602393) orexin receptor type 2 [H ( 444) 355 75.1 4e-13
XP_016866287 (OMIM: 602393) PREDICTED: orexin rece ( 461) 355 75.1 4.1e-13
NP_000397 (OMIM: 138850,146110) gonadotropin-relea ( 328) 335 71.3 4.1e-12
NP_001287862 (OMIM: 608584,608595) neuropeptide S ( 366) 329 70.3 9.2e-12
NP_000612 (OMIM: 103780,164230,181500,182135,60678 ( 471) 327 70.1 1.4e-11
XP_016856596 (OMIM: 602392) PREDICTED: orexin rece ( 389) 325 69.6 1.6e-11
XP_016856594 (OMIM: 602392) PREDICTED: orexin rece ( 425) 319 68.6 3.6e-11
NP_001516 (OMIM: 602392) orexin receptor type 1 [H ( 425) 319 68.6 3.6e-11
XP_016856595 (OMIM: 602392) PREDICTED: orexin rece ( 425) 319 68.6 3.6e-11
NP_795344 (OMIM: 118445) gastrin/cholecystokinin t ( 447) 318 68.4 4.2e-11
XP_005253267 (OMIM: 118445) PREDICTED: gastrin/cho ( 516) 318 68.5 4.5e-11
NP_001138757 (OMIM: 600018) mu-type opioid recepto ( 389) 305 66.0 1.9e-10
NP_001008504 (OMIM: 600018) mu-type opioid recepto ( 392) 305 66.0 1.9e-10
NP_001138755 (OMIM: 600018) mu-type opioid recepto ( 397) 305 66.0 2e-10
NP_000905 (OMIM: 600018) mu-type opioid receptor i ( 400) 305 66.0 2e-10
NP_001138756 (OMIM: 600018) mu-type opioid recepto ( 403) 305 66.0 2e-10
NP_001138754 (OMIM: 600018) mu-type opioid recepto ( 406) 305 66.0 2e-10
NP_001272452 (OMIM: 600018) mu-type opioid recepto ( 414) 305 66.0 2e-10
NP_001008503 (OMIM: 600018) mu-type opioid recepto ( 418) 305 66.0 2e-10
NP_001138758 (OMIM: 600018) mu-type opioid recepto ( 420) 305 66.0 2e-10
NP_000670 (OMIM: 104220) alpha-1B adrenergic recep ( 520) 306 66.3 2.1e-10
NP_001008505 (OMIM: 600018) mu-type opioid recepto ( 446) 305 66.0 2.1e-10
NP_001272453 (OMIM: 600018) mu-type opioid recepto ( 493) 305 66.1 2.3e-10
NP_001138751 (OMIM: 600018) mu-type opioid recepto ( 493) 305 66.1 2.3e-10
XP_016874005 (OMIM: 118445) PREDICTED: gastrin/cho ( 381) 287 62.7 1.8e-09
NP_001186948 (OMIM: 602548) nociceptin receptor is ( 370) 286 62.5 2e-09
XP_016883343 (OMIM: 602548) PREDICTED: nociceptin ( 370) 286 62.5 2e-09
NP_872588 (OMIM: 602548) nociceptin receptor isofo ( 370) 286 62.5 2e-09
NP_000904 (OMIM: 602548) nociceptin receptor isofo ( 370) 286 62.5 2e-09
XP_016883342 (OMIM: 602548) PREDICTED: nociceptin ( 388) 286 62.5 2.1e-09
XP_016883341 (OMIM: 602548) PREDICTED: nociceptin ( 388) 286 62.5 2.1e-09
XP_011527130 (OMIM: 602548) PREDICTED: nociceptin ( 388) 286 62.5 2.1e-09
NP_001305782 (OMIM: 602548) nociceptin receptor is ( 399) 286 62.6 2.1e-09
NP_001050 (OMIM: 162332,614840) neuromedin-K recep ( 465) 285 62.5 2.7e-09
XP_011527461 (OMIM: 244200,607123) PREDICTED: prok ( 348) 282 61.8 3.2e-09
XP_016883135 (OMIM: 244200,607123) PREDICTED: prok ( 384) 282 61.8 3.4e-09
NP_658986 (OMIM: 244200,607123) prokineticin recep ( 384) 282 61.8 3.4e-09
NP_001305783 (OMIM: 602548) nociceptin receptor is ( 365) 280 61.4 4.3e-09
XP_016883344 (OMIM: 602548) PREDICTED: nociceptin ( 365) 280 61.4 4.3e-09
NP_062873 (OMIM: 182137) 5-hydroxytryptamine recep ( 479) 281 61.8 4.5e-09
>>NP_000698 (OMIM: 600264) vasopressin V1b receptor [Hom (424 aa)
initn: 2883 init1: 2883 opt: 2883 Z-score: 2824.6 bits: 531.7 E(85289): 1.4e-150
Smith-Waterman score: 2883; 100.0% identity (100.0% similar) in 424 aa overlap (1-424:1-424)
10 20 30 40 50 60
pF1KE0 MDSGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNLAVLLTLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MDSGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNLAVLLTLG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 QLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 STYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 STYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 SGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 GGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFFSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFFSV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 QMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHLACCGGPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHLACCGGPQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 PRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRPRPEESPRDLELADGEGTAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRPRPEESPRDLELADGEGTAE
370 380 390 400 410 420
pF1KE0 TIIF
::::
NP_000 TIIF
>>NP_000697 (OMIM: 600821) vasopressin V1a receptor [Hom (418 aa)
initn: 1257 init1: 844 opt: 1252 Z-score: 1232.5 bits: 237.1 E(85289): 6.5e-62
Smith-Waterman score: 1254; 51.4% identity (75.5% similar) in 383 aa overlap (2-377:14-386)
10 20 30 40
pF1KE0 MDSGPLWD----ANPTPRGTLSAPNATTPWLG-RDEELAKVEIGVLAT
.:.: : :. : : . . ... : :.:::::.::.:::.
NP_000 MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 VLVLATGGNLAVLLTLGQLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGP
....:. :: .:::.: . :: ::::::. ::.:.:::::.::::::. :::::::.::
NP_000 TFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 DLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAI
: :::.::.:::..::::.:::..:: :::.::::::..::::.. . :.::: :.:. .
NP_000 DWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFV
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE0 FSLPQVFIFSLREVIQGSGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLIC
.: :: :.::. :: . . . :::: : ::: :::.:: : .::: ::..: .::..::
NP_000 LSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFIC
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE0 HEICKNLKVKTQAWRVGGGGWRTWDRPSPSTLAATTRG--LPSRVSSINTISRAKIRTVK
..: :.. :: . . : . .. .: .: : :::...::::::::::
NP_000 YNIWCNVRGKTASRQSKG---------AEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVK
250 260 270 280 290
290 300 310 320 330 340
pF1KE0 MTFVIVLAYIACWAPFFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGF
:::::: :::.:::::: .::::::: . .: : ..::. :::.::::::::::: :
NP_000 MTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFF
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE0 NSHLLPRPLRHLACCGGPQPRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRP
..::: .. . :: . . .. .. .: :.: :.:
NP_000 SGHLLQDCVQSFPCCQNMKEKFNKEDTD-SMSRRQTFYSNNRSPTNSTGMWKDSPKSSKS
360 370 380 390 400 410
410 420
pF1KE0 RPEESPRDLELADGEGTAETIIF
NP_000 IKFIPVST
>>NP_000907 (OMIM: 167055) oxytocin receptor [Homo sapie (389 aa)
initn: 1154 init1: 494 opt: 812 Z-score: 803.3 bits: 157.6 E(85289): 5.2e-38
Smith-Waterman score: 1224; 52.3% identity (75.5% similar) in 371 aa overlap (8-378:15-368)
10 20 30 40 50
pF1KE0 MDSGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNL
.:. .: :. . .: : :.: ::.::..:: .:.:: .::
NP_000 MEGALAANWSAEAANASAAPPGAEGNRTAGPP--RRNEALARVEVAVLCLILLLALSGNA
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 AVLLTLGQLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYL
:::.: .:.::. .:. ::...::.::.::::::::::::.:: ::::::: ::::
NP_000 CVLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 QVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFSLPQVFIFS
::..::::::.:: :.::: ::.:.:::::.. .. : . : :: . : ::: :::
NP_000 QVVGMFASTYLLLLMSLDRCLAICQPLRSLRR--RTDRLAVLATWLGCLVASAPQVHIFS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 LREVIQGSGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVK
:::: ..::.:::: : ::::.::.:: :::....:: .:.:::.:: .: .::..:
NP_000 LREV--ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 TQAWRVGGGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIAC
: : .. . : .. . : .::::.. ::.::::::::::.::::.:.:
NP_000 TAAAAAA-------EAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVC
240 250 260 270 280
300 310 320 330 340 350
pF1KE0 WAPFFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHL
:.::: :::::::: ::: : : :: : :::..::::::::::: :..::. . ....
NP_000 WTPFFFVQMWSVWDANAPKEAS---AFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRF
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE0 ACCGGPQPRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRPRPEESPRDLELA
::.. . :: :.. : :.. ..
NP_000 LCCSASYLKGRR-LGETSASKKSNSSSFVLSHRSSSQRSCSQPSTA
350 360 370 380
>>XP_011532064 (OMIM: 167055) PREDICTED: oxytocin recept (389 aa)
initn: 1154 init1: 494 opt: 812 Z-score: 803.3 bits: 157.6 E(85289): 5.2e-38
Smith-Waterman score: 1224; 52.3% identity (75.5% similar) in 371 aa overlap (8-378:15-368)
10 20 30 40 50
pF1KE0 MDSGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNL
.:. .: :. . .: : :.: ::.::..:: .:.:: .::
XP_011 MEGALAANWSAEAANASAAPPGAEGNRTAGPP--RRNEALARVEVAVLCLILLLALSGNA
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 AVLLTLGQLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYL
:::.: .:.::. .:. ::...::.::.::::::::::::.:: ::::::: ::::
XP_011 CVLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 QVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFSLPQVFIFS
::..::::::.:: :.::: ::.:.:::::.. .. : . : :: . : ::: :::
XP_011 QVVGMFASTYLLLLMSLDRCLAICQPLRSLRR--RTDRLAVLATWLGCLVASAPQVHIFS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 LREVIQGSGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVK
:::: ..::.:::: : ::::.::.:: :::....:: .:.:::.:: .: .::..:
XP_011 LREV--ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 TQAWRVGGGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIAC
: : .. . : .. . : .::::.. ::.::::::::::.::::.:.:
XP_011 TAAAAAA-------EAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVC
240 250 260 270 280
300 310 320 330 340 350
pF1KE0 WAPFFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHL
:.::: :::::::: ::: : : :: : :::..::::::::::: :..::. . ....
XP_011 WTPFFFVQMWSVWDANAPKEAS---AFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRF
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE0 ACCGGPQPRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRPRPEESPRDLELA
::.. . :: :.. : :.. ..
XP_011 LCCSASYLKGRR-LGETSASKKSNSSSFVLSHRSSSQRSCSQPSTA
350 360 370 380
>>NP_001139623 (OMIM: 300538,300539,304800) vasopressin (309 aa)
initn: 821 init1: 352 opt: 668 Z-score: 663.9 bits: 131.4 E(85289): 3.1e-30
Smith-Waterman score: 811; 44.3% identity (68.6% similar) in 309 aa overlap (10-313:13-303)
10 20 30 40 50
pF1KE0 MDSGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNLAVLL
.:. . : . : :: ::..:...:. :.: .. .: ::
NP_001 MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 TLGQLGRKR--SRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYLQV
.:.. ::. . .:.:. :: :.::::::::::::: : : ::.::: :::::::::.
NP_001 ALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQM
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 LSMFASTYMLLAMTLDRYLAVCHPLRSLQQPGQSTY---LLIAAPWLLAAIFSLPQVFIF
..:.::.::.:::::::. :.:.:. . .. . . . .:.: : .. ..::::.:::
NP_001 VGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVA--WAFSLLLSLPQLFIF
130 140 150 160 170
180 190 200 210 220 230
pF1KE0 SLREVIQGSGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKV
. :.: :::: :::: :. ::: :.:.:: .: .:: :. ..:: :: .:: .: :
NP_001 AQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASL-V
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 KTQAWRVGGGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIA
. : :: : : . : :.. . . : : .::.::.:::..:.
NP_001 PGPSERPGG---RRRGRRT---------GSPGEGAHV---SAAVAKTVRMTLVIVVVYVL
240 250 260 270 280
300 310 320 330 340 350
pF1KE0 CWAPFFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRH
:::::: ::.:..:: .:: :
NP_001 CWAPFFLVQLWAAWDPEAPLEGGCSRG
290 300
>>NP_000045 (OMIM: 300538,300539,304800) vasopressin V2 (371 aa)
initn: 931 init1: 352 opt: 668 Z-score: 663.0 bits: 131.5 E(85289): 3.4e-30
Smith-Waterman score: 933; 44.4% identity (67.4% similar) in 356 aa overlap (10-361:13-348)
10 20 30 40 50
pF1KE0 MDSGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNLAVLL
.:. . : . : :: ::..:...:. :.: .. .: ::
NP_000 MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 TLGQLGRKR--SRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYLQV
.:.. ::. . .:.:. :: :.::::::::::::: : : ::.::: :::::::::.
NP_000 ALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQM
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 LSMFASTYMLLAMTLDRYLAVCHPLRSLQQ-PGQSTYLLIAAPWLLAAIFSLPQVFIFSL
..:.::.::.:::::::. :.:.:. . .. : . . : .. ..::::.:::.
NP_000 VGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQ
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 REVIQGSGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKT
:.: :::: :::: :. ::: :.:.:: .: .:: :. ..:: :: .:: .: :
NP_000 RNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASL-VPG
190 200 210 220 230
240 250 260 270 280 290
pF1KE0 QAWRVGGGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACW
. : :: : : . : :.. . . : : .::.::.:::..:. ::
NP_000 PSERPGG---RRRGRRT---------GSPGEGAHV---SAAVAKTVRMTLVIVVVYVLCW
240 250 260 270 280
300 310 320 330 340 350
pF1KE0 APFFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHLA
:::: ::.:..:: .:: : .. :.. :::..:::: ::::: .:.: . :: :
NP_000 APFFLVQLWAAWDPEAPLE---GAPFVLLMLLASLNSCTNPWIYASFSSSV-SSELRSLL
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE0 CCG-GPQPRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRPRPEESPRDLELA
::. : :
NP_000 CCARGRTPPSLGPQDESCTTASSSLAKDTSS
350 360 370
>>XP_006724891 (OMIM: 300538,300539,304800) PREDICTED: v (371 aa)
initn: 931 init1: 352 opt: 668 Z-score: 663.0 bits: 131.5 E(85289): 3.4e-30
Smith-Waterman score: 933; 44.4% identity (67.4% similar) in 356 aa overlap (10-361:13-348)
10 20 30 40 50
pF1KE0 MDSGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNLAVLL
.:. . : . : :: ::..:...:. :.: .. .: ::
XP_006 MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 TLGQLGRKR--SRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYLQV
.:.. ::. . .:.:. :: :.::::::::::::: : : ::.::: :::::::::.
XP_006 ALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQM
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 LSMFASTYMLLAMTLDRYLAVCHPLRSLQQ-PGQSTYLLIAAPWLLAAIFSLPQVFIFSL
..:.::.::.:::::::. :.:.:. . .. : . . : .. ..::::.:::.
XP_006 VGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQ
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 REVIQGSGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKT
:.: :::: :::: :. ::: :.:.:: .: .:: :. ..:: :: .:: .: :
XP_006 RNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASL-VPG
190 200 210 220 230
240 250 260 270 280 290
pF1KE0 QAWRVGGGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACW
. : :: : : . : :.. . . : : .::.::.:::..:. ::
XP_006 PSERPGG---RRRGRRT---------GSPGEGAHV---SAAVAKTVRMTLVIVVVYVLCW
240 250 260 270 280
300 310 320 330 340 350
pF1KE0 APFFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHLA
:::: ::.:..:: .:: : .. :.. :::..:::: ::::: .:.: . :: :
XP_006 APFFLVQLWAAWDPEAPLE---GAPFVLLMLLASLNSCTNPWIYASFSSSV-SSELRSLL
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE0 CCG-GPQPRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRPRPEESPRDLELA
::. : :
XP_006 CCARGRTPPSLGPQDESCTTASSSLAKDTSS
350 360 370
>>NP_997055 (OMIM: 608584,608595) neuropeptide S recepto (371 aa)
initn: 477 init1: 267 opt: 415 Z-score: 416.0 bits: 85.8 E(85289): 2e-16
Smith-Waterman score: 539; 30.4% identity (63.4% similar) in 352 aa overlap (3-345:15-337)
10 20 30 40
pF1KE0 MDSGPLWDANP---TPRGTLSAPNATTPWLGRDEELAKVEIGVLATVL
.: :..: : :.. : . . .. .: ...
NP_997 MPANFTEGSFDSSGTGQTLDSSPVACTETVTFTEVVEGKEWGSFYYSFKTEQLITLWVLF
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 VLATGGNLAVLLTLGQLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDL
:.. :: .::.. . .:.::: .:: .::.:: ..: ..: .. : .: : .:::
NP_997 VFTIVGNSVVLFSTWRR-KKKSRMTFFVTQLAITDSFTGLVNILTDINWRFTGDFTAPDL
70 80 90 100 110
110 120 130 140 150 160
pF1KE0 LCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFS
.::.:.::::. ..::::.:.....::: :. .:.. :: :. :.. : : :. .::
NP_997 VCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQARVLIVIA-WSLSFLFS
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE0 LPQVFIFSLREVIQGSGVLDCWA---DFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLI
.: ..::. : . ..: ..::: : .. : : :.: ... .. .:.:... :...
NP_997 IPTLIIFGKRTL--SNGEVQCWALWPDDSY-WTP--YMTIVAFLVYFIPLTIISIMYGIV
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE0 CHEICKNLKVKTQAWRVGGGGWRTWDRPSPSTLAAT-TRGLPSRVSSINTISRAKIRTVK
... .:...... . . : . : .. .::: ::.:::...:
NP_997 ----IRTIWIKSKTYET------VISNCSDGKLCSSYNRGL---------ISKAKIKAIK
240 250 260 270
290 300 310 320 330
pF1KE0 MTFVIVLAYIACWAPFFSVQMWSVWDKNA--PDEDSTNVAFTISMLLGNLNSCCNPWIYM
....:.::.: ::.:.: .... :. :: . : .: . : ::: :: ::
NP_997 YSIIIILAFICCWSPYF---LFDILDNFNLLPDTQERFYASVIIQNLPALNSAINPLIYC
280 290 300 310 320 330
340 350 360 370 380 390
pF1KE0 GFNSHLLPRPLRHLACCGGPQPRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSG
:.: .
NP_997 VFSSSISFPCREQRSQDSRMTFRERTERHEMQILSKPEFI
340 350 360 370
>>NP_997056 (OMIM: 608584,608595) neuropeptide S recepto (377 aa)
initn: 477 init1: 267 opt: 415 Z-score: 415.9 bits: 85.8 E(85289): 2e-16
Smith-Waterman score: 539; 30.4% identity (63.4% similar) in 352 aa overlap (3-345:15-337)
10 20 30 40
pF1KE0 MDSGPLWDANP---TPRGTLSAPNATTPWLGRDEELAKVEIGVLATVL
.: :..: : :.. : . . .. .: ...
NP_997 MPANFTEGSFDSSGTGQTLDSSPVACTETVTFTEVVEGKEWGSFYYSFKTEQLITLWVLF
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 VLATGGNLAVLLTLGQLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDL
:.. :: .::.. . .:.::: .:: .::.:: ..: ..: .. : .: : .:::
NP_997 VFTIVGNSVVLFSTWRR-KKKSRMTFFVTQLAITDSFTGLVNILTDINWRFTGDFTAPDL
70 80 90 100 110
110 120 130 140 150 160
pF1KE0 LCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFS
.::.:.::::. ..::::.:.....::: :. .:.. :: :. :.. : : :. .::
NP_997 VCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQARVLIVIA-WSLSFLFS
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE0 LPQVFIFSLREVIQGSGVLDCWA---DFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLI
.: ..::. : . ..: ..::: : .. : : :.: ... .. .:.:... :...
NP_997 IPTLIIFGKRTL--SNGEVQCWALWPDDSY-WTP--YMTIVAFLVYFIPLTIISIMYGIV
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE0 CHEICKNLKVKTQAWRVGGGGWRTWDRPSPSTLAAT-TRGLPSRVSSINTISRAKIRTVK
... .:...... . . : . : .. .::: ::.:::...:
NP_997 ----IRTIWIKSKTYET------VISNCSDGKLCSSYNRGL---------ISKAKIKAIK
240 250 260 270
290 300 310 320 330
pF1KE0 MTFVIVLAYIACWAPFFSVQMWSVWDKNA--PDEDSTNVAFTISMLLGNLNSCCNPWIYM
....:.::.: ::.:.: .... :. :: . : .: . : ::: :: ::
NP_997 YSIIIILAFICCWSPYF---LFDILDNFNLLPDTQERFYASVIIQNLPALNSAINPLIYC
280 290 300 310 320 330
340 350 360 370 380 390
pF1KE0 GFNSHLLPRPLRHLACCGGPQPRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSG
:.: .
NP_997 VFSSSISFPCRVIRLRQLQEAALMLCPQRENWKGTWPGVPSWALPR
340 350 360 370
>>NP_001287864 (OMIM: 608584,608595) neuropeptide S rece (390 aa)
initn: 493 init1: 283 opt: 415 Z-score: 415.8 bits: 85.8 E(85289): 2e-16
Smith-Waterman score: 539; 30.4% identity (63.4% similar) in 352 aa overlap (3-345:15-337)
10 20 30 40
pF1KE0 MDSGPLWDANP---TPRGTLSAPNATTPWLGRDEELAKVEIGVLATVL
.: :..: : :.. : . . .. .: ...
NP_001 MPANFTEGSFDSSGTGQTLDSSPVACTETVTFTEVVEGKEWGSFYYSFKTEQLITLWVLF
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 VLATGGNLAVLLTLGQLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDL
:.. :: .::.. . .:.::: .:: .::.:: ..: ..: .. : .: : .:::
NP_001 VFTIVGNSVVLFSTWRR-KKKSRMTFFVTQLAITDSFTGLVNILTDINWRFTGDFTAPDL
70 80 90 100 110
110 120 130 140 150 160
pF1KE0 LCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFS
.::.:.::::. ..::::.:.....::: :. .:.. :: :. :.. : : :. .::
NP_001 VCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQARVLIVIA-WSLSFLFS
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE0 LPQVFIFSLREVIQGSGVLDCWA---DFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLI
.: ..::. : . ..: ..::: : .. : : :.: ... .. .:.:... :...
NP_001 IPTLIIFGKRTL--SNGEVQCWALWPDDSY-WTP--YMTIVAFLVYFIPLTIISIMYGIV
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE0 CHEICKNLKVKTQAWRVGGGGWRTWDRPSPSTLAAT-TRGLPSRVSSINTISRAKIRTVK
... .:...... . . : . : .. .::: ::.:::...:
NP_001 ----IRTIWIKSKTYET------VISNCSDGKLCSSYNRGL---------ISKAKIKAIK
240 250 260 270
290 300 310 320 330
pF1KE0 MTFVIVLAYIACWAPFFSVQMWSVWDKNA--PDEDSTNVAFTISMLLGNLNSCCNPWIYM
....:.::.: ::.:.: .... :. :: . : .: . : ::: :: ::
NP_001 YSIIIILAFICCWSPYF---LFDILDNFNLLPDTQERFYASVIIQNLPALNSAINPLIYC
280 290 300 310 320 330
340 350 360 370 380 390
pF1KE0 GFNSHLLPRPLRHLACCGGPQPRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSG
:.: .
NP_001 VFSSSISFPCRANSSVYLLACDVSVLWALVLTSEKESCESWRRKGAKITGFQNDVPGEN
340 350 360 370 380 390
424 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 04:23:34 2016 done: Sat Nov 5 04:23:36 2016
Total Scan time: 9.370 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]