Result of FASTA (ccds) for
pF1KE0729
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0729, 309 aa
1>>>pF1KE0729 309 - 309 aa - 309 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.7083+/-0.00115; mu= 2.8108+/- 0.066
mean_var=219.3992+/-53.000, 0's: 0 Z-trim(108.8): 695 B-trim: 90 in 1/49
Lambda= 0.086588
statistics sampled from 9608 (10430) to 9608 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.32), width: 16
Scan time: 2.570
The best scores are: opt bits E(32554)
CCDS33128.1 AURKC gene_id:6795|Hs108|chr19 ( 309) 2070 271.7 4.9e-73
CCDS46205.1 AURKC gene_id:6795|Hs108|chr19 ( 290) 1946 256.2 2.2e-68
CCDS46206.1 AURKC gene_id:6795|Hs108|chr19 ( 275) 1855 244.8 5.6e-65
CCDS67162.1 AURKB gene_id:9212|Hs108|chr17 ( 345) 1596 212.6 3.5e-55
CCDS11134.1 AURKB gene_id:9212|Hs108|chr17 ( 344) 1594 212.3 4.2e-55
CCDS58514.1 AURKB gene_id:9212|Hs108|chr17 ( 303) 1582 210.8 1.1e-54
CCDS13451.1 AURKA gene_id:6790|Hs108|chr20 ( 403) 1316 177.7 1.3e-44
CCDS82065.1 AURKB gene_id:9212|Hs108|chr17 ( 312) 1204 163.6 1.8e-40
CCDS60974.1 SIK3 gene_id:23387|Hs108|chr11 (1261) 618 91.0 5e-18
CCDS8379.2 SIK3 gene_id:23387|Hs108|chr11 (1321) 618 91.0 5.2e-18
CCDS3735.1 PLK4 gene_id:10733|Hs108|chr4 ( 970) 609 89.8 9.2e-18
CCDS55947.1 MARK3 gene_id:4140|Hs108|chr14 ( 713) 600 88.5 1.6e-17
CCDS41993.1 MARK3 gene_id:4140|Hs108|chr14 ( 729) 600 88.5 1.7e-17
CCDS45166.1 MARK3 gene_id:4140|Hs108|chr14 ( 744) 600 88.5 1.7e-17
CCDS45165.1 MARK3 gene_id:4140|Hs108|chr14 ( 753) 600 88.5 1.7e-17
CCDS12658.1 MARK4 gene_id:57787|Hs108|chr19 ( 688) 589 87.1 4.2e-17
CCDS56097.1 MARK4 gene_id:57787|Hs108|chr19 ( 752) 589 87.2 4.4e-17
CCDS31892.1 NUAK1 gene_id:9891|Hs108|chr12 ( 661) 588 87.0 4.4e-17
CCDS73034.1 MARK1 gene_id:4139|Hs108|chr1 ( 780) 586 86.8 5.9e-17
CCDS31029.2 MARK1 gene_id:4139|Hs108|chr1 ( 795) 586 86.8 5.9e-17
CCDS73033.1 MARK1 gene_id:4139|Hs108|chr1 ( 796) 586 86.8 5.9e-17
CCDS33575.1 SIK1 gene_id:150094|Hs108|chr21 ( 783) 574 85.3 1.7e-16
CCDS82645.1 LOC102724428 gene_id:102724428|Hs108|c ( 783) 574 85.3 1.7e-16
CCDS58750.1 STK36 gene_id:27148|Hs108|chr2 (1294) 576 85.8 2e-16
CCDS2421.1 STK36 gene_id:27148|Hs108|chr2 (1315) 576 85.8 2e-16
CCDS43075.1 SNRK gene_id:54861|Hs108|chr3 ( 765) 570 84.8 2.3e-16
CCDS53651.1 MARK2 gene_id:2011|Hs108|chr11 ( 709) 568 84.5 2.6e-16
CCDS53650.1 MARK2 gene_id:2011|Hs108|chr11 ( 719) 568 84.5 2.6e-16
CCDS8051.2 MARK2 gene_id:2011|Hs108|chr11 ( 724) 568 84.5 2.6e-16
CCDS41665.1 MARK2 gene_id:2011|Hs108|chr11 ( 745) 568 84.5 2.7e-16
CCDS58411.1 PDPK1 gene_id:5170|Hs108|chr16 ( 454) 564 83.8 2.7e-16
CCDS53649.1 MARK2 gene_id:2011|Hs108|chr11 ( 788) 568 84.5 2.8e-16
CCDS10472.1 PDPK1 gene_id:5170|Hs108|chr16 ( 556) 564 83.9 3.1e-16
CCDS6625.1 PRKACG gene_id:5568|Hs108|chr9 ( 351) 557 82.8 4.2e-16
CCDS8347.1 SIK2 gene_id:23235|Hs108|chr11 ( 926) 562 83.9 5.2e-16
CCDS14125.1 PRKX gene_id:5613|Hs108|chrX ( 358) 553 82.3 6.1e-16
CCDS76779.1 ULK3 gene_id:25989|Hs108|chr15 ( 470) 552 82.3 7.9e-16
CCDS45305.1 ULK3 gene_id:25989|Hs108|chr15 ( 472) 552 82.3 7.9e-16
CCDS12304.1 PRKACA gene_id:5566|Hs108|chr19 ( 351) 549 81.8 8.5e-16
CCDS72813.1 PRKACB gene_id:5567|Hs108|chr1 ( 339) 546 81.4 1.1e-15
CCDS691.1 PRKACB gene_id:5567|Hs108|chr1 ( 351) 546 81.4 1.1e-15
CCDS1453.2 NUAK2 gene_id:81788|Hs108|chr1 ( 672) 551 82.3 1.1e-15
CCDS55610.1 PRKACB gene_id:5567|Hs108|chr1 ( 355) 546 81.4 1.1e-15
CCDS72815.1 PRKACB gene_id:5567|Hs108|chr1 ( 357) 546 81.4 1.1e-15
CCDS9752.1 PRKCH gene_id:5583|Hs108|chr14 ( 683) 551 82.4 1.1e-15
CCDS55609.1 PRKACB gene_id:5567|Hs108|chr1 ( 358) 546 81.4 1.1e-15
CCDS693.1 PRKACB gene_id:5567|Hs108|chr1 ( 398) 546 81.5 1.2e-15
CCDS12305.1 PRKACA gene_id:5566|Hs108|chr19 ( 343) 543 81.0 1.4e-15
CCDS72816.1 PRKACB gene_id:5567|Hs108|chr1 ( 338) 538 80.4 2.1e-15
CCDS2582.1 CAMK1 gene_id:8536|Hs108|chr3 ( 370) 533 79.8 3.5e-15
>>CCDS33128.1 AURKC gene_id:6795|Hs108|chr19 (309 aa)
initn: 2070 init1: 2070 opt: 2070 Z-score: 1424.6 bits: 271.7 E(32554): 4.9e-73
Smith-Waterman score: 2070; 100.0% identity (100.0% similar) in 309 aa overlap (1-309:1-309)
10 20 30 40 50 60
pF1KE0 MSSPRAVVQLGKAQPAGEELATANQTAQQPSSPAMRRLTVDDFEIGRPLGKGKFGNVYLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 MSSPRAVVQLGKAQPAGEELATANQTAQQPSSPAMRRLTVDDFEIGRPLGKGKFGNVYLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 RLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 RLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLIL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 EYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 EYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 KIADFGWSVHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 KIADFGWSVHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 SASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLAQILKHPWVQAHSRRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 SASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLAQILKHPWVQAHSRRV
250 260 270 280 290 300
pF1KE0 LPPCAQMAS
:::::::::
CCDS33 LPPCAQMAS
>>CCDS46205.1 AURKC gene_id:6795|Hs108|chr19 (290 aa)
initn: 1946 init1: 1946 opt: 1946 Z-score: 1341.3 bits: 256.2 E(32554): 2.2e-68
Smith-Waterman score: 1946; 99.7% identity (100.0% similar) in 290 aa overlap (20-309:1-290)
10 20 30 40 50 60
pF1KE0 MSSPRAVVQLGKAQPAGEELATANQTAQQPSSPAMRRLTVDDFEIGRPLGKGKFGNVYLA
.::::::::::::::::::::::::::::::::::::::::
CCDS46 MATANQTAQQPSSPAMRRLTVDDFEIGRPLGKGKFGNVYLA
10 20 30 40
70 80 90 100 110 120
pF1KE0 RLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 RLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLIL
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE0 EYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 EYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEV
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE0 KIADFGWSVHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 KIADFGWSVHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFE
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE0 SASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLAQILKHPWVQAHSRRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 SASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLAQILKHPWVQAHSRRV
230 240 250 260 270 280
pF1KE0 LPPCAQMAS
:::::::::
CCDS46 LPPCAQMAS
290
>>CCDS46206.1 AURKC gene_id:6795|Hs108|chr19 (275 aa)
initn: 1855 init1: 1855 opt: 1855 Z-score: 1280.1 bits: 244.8 E(32554): 5.6e-65
Smith-Waterman score: 1855; 100.0% identity (100.0% similar) in 275 aa overlap (35-309:1-275)
10 20 30 40 50 60
pF1KE0 RAVVQLGKAQPAGEELATANQTAQQPSSPAMRRLTVDDFEIGRPLGKGKFGNVYLARLKE
::::::::::::::::::::::::::::::
CCDS46 MRRLTVDDFEIGRPLGKGKFGNVYLARLKE
10 20 30
70 80 90 100 110 120
pF1KE0 SHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 SHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAP
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE0 RGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 RGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIAD
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE0 FGWSVHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 FGWSVHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASH
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE0 SETYRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLAQILKHPWVQAHSRRVLPPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 SETYRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLAQILKHPWVQAHSRRVLPPC
220 230 240 250 260 270
pF1KE0 AQMAS
:::::
CCDS46 AQMAS
>>CCDS67162.1 AURKB gene_id:9212|Hs108|chr17 (345 aa)
initn: 1563 init1: 1563 opt: 1596 Z-score: 1104.1 bits: 212.6 E(32554): 3.5e-55
Smith-Waterman score: 1596; 76.8% identity (90.8% similar) in 306 aa overlap (3-305:35-340)
10 20
pF1KE0 MSSPRAVVQLGKA--QP-AGEELATANQTAQQ
.: :.: .... :: :. . ....
CCDS67 ENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMENSSGT
10 20 30 40 50 60
30 40 50 60 70 80
pF1KE0 PSSPAMRRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLR
:. . :..:.::::::::::::::::::::: :.:::::::::::::::::::.:::::
CCDS67 PDILTRRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLR
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE0 REIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEE
:::::::::.:::::::::::.: ::.::::::::::::::::::: .::::::::.::
CCDS67 REIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEE
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE0 LADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKTMCGTLDYLPPE
::::: ::: ::::::::::::::::..::.::::::::::.::::::::::::::::::
CCDS67 LADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPE
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE0 MIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDL
::::: ..:::::::::::::::::: ::::::::.::::::.:::..:: :.:.::.::
CCDS67 MIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDL
250 260 270 280 290 300
270 280 290 300
pF1KE0 ISRLLRYQPLERLPLAQILKHPWVQAHSRRVLPPCAQMAS
::.:::..: :::::::. ::::.:.::::::: :
CCDS67 ISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
310 320 330 340
>>CCDS11134.1 AURKB gene_id:9212|Hs108|chr17 (344 aa)
initn: 1580 init1: 1580 opt: 1594 Z-score: 1102.7 bits: 212.3 E(32554): 4.2e-55
Smith-Waterman score: 1594; 77.0% identity (90.6% similar) in 309 aa overlap (3-305:35-339)
10 20 30
pF1KE0 MSSPRAVVQLGKA--QPAGEELATANQTAQQP
.: :.: .... ::. :. .: ...
CCDS11 ENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPT----AAPGQKVMEN
10 20 30 40 50 60
40 50 60 70 80
pF1KE0 SS--PAM--RRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEH
:: : . :..:.::::::::::::::::::::: :.:::::::::::::::::::.::
CCDS11 SSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEH
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE0 QLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATI
::::::::::::.:::::::::::.: ::.::::::::::::::::::: .::::::::
CCDS11 QLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATI
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE0 IEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKTMCGTLDYL
.::::::: ::: ::::::::::::::::..::.::::::::::.:::::::::::::::
CCDS11 MEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYL
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE0 PPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGA
:::::::: ..:::::::::::::::::: ::::::::.::::::.:::..:: :.:.::
CCDS11 PPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGA
250 260 270 280 290 300
270 280 290 300
pF1KE0 RDLISRLLRYQPLERLPLAQILKHPWVQAHSRRVLPPCAQMAS
.::::.:::..: :::::::. ::::.:.::::::: :
CCDS11 QDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
310 320 330 340
>>CCDS58514.1 AURKB gene_id:9212|Hs108|chr17 (303 aa)
initn: 1580 init1: 1580 opt: 1582 Z-score: 1095.3 bits: 210.8 E(32554): 1.1e-54
Smith-Waterman score: 1582; 80.6% identity (92.7% similar) in 289 aa overlap (21-305:10-298)
10 20 30 40 50
pF1KE0 MSSPRAVVQLGKAQPAGEELATANQTAQQPSS--PAM--RRLTVDDFEIGRPLGKGKFGN
:. .: ... :: : . :..:.::::::::::::::::
CCDS58 MSRSNVQPTAAPGQKVMENSSGTPDILTRHFTIDDFEIGRPLGKGKFGN
10 20 30 40
60 70 80 90 100 110
pF1KE0 VYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRV
::::: :.:::::::::::::::::::.::::::::::::::.:::::::::::.: ::.
CCDS58 VYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRI
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE0 YLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGF
::::::::::::::::::: .::::::::.::::::: ::: ::::::::::::::::.
CCDS58 YLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGL
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE0 RGEVKIADFGWSVHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGY
.::.::::::::::.::::::::::::::::::::::: ..::::::::::::::::::
CCDS58 KGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGN
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE0 PPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLAQILKHPWVQAH
::::::::.::::::.:::..:: :.:.::.::::.:::..: :::::::. ::::.:.
CCDS58 PPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLRHNPSERLPLAQVSAHPWVRAN
230 240 250 260 270 280
300
pF1KE0 SRRVLPPCAQMAS
::::::: :
CCDS58 SRRVLPPSALQSVA
290 300
>>CCDS13451.1 AURKA gene_id:6790|Hs108|chr20 (403 aa)
initn: 1300 init1: 1300 opt: 1316 Z-score: 914.2 bits: 177.7 E(32554): 1.3e-44
Smith-Waterman score: 1316; 68.1% identity (86.5% similar) in 282 aa overlap (18-299:112-389)
10 20 30 40
pF1KE0 MSSPRAVVQLGKAQPAGEELATANQTAQQPSSPAMRRLTVDDFEIGR
::::. ... .. . :. ...::::::
CCDS13 TSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKNEESKK----RQWALEDFEIGR
90 100 110 120 130
50 60 70 80 90 100
pF1KE0 PLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLY
:::::::::::::: :.:.::.:::::::.:.:: :.:::::::.:::.::.::::::::
CCDS13 PLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLY
140 150 160 170 180 190
110 120 130 140 150 160
pF1KE0 NYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDI
.::::: :::::::::: : .:.:::: :.::::::: : :::.::.:::.:.::::::
CCDS13 GYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDI
200 210 220 230 240 250
170 180 190 200 210 220
pF1KE0 KPENLLLGFRGEVKIADFGWSVHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGV
:::::::: ::.::::::::::.:: :: :.::::::::::::::: .::::::: .::
CCDS13 KPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGV
260 270 280 290 300 310
230 240 250 260 270 280
pF1KE0 LCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLAQI
::::.::: ::::. ...:::.:: .:. :: . ::::::::::...: .: : ..
CCDS13 LCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREV
320 330 340 350 360 370
290 300
pF1KE0 LKHPWVQAHSRRVLPPCAQMAS
:.:::. :.: .
CCDS13 LEHPWITANSSKPSNCQNKESASKQS
380 390 400
>>CCDS82065.1 AURKB gene_id:9212|Hs108|chr17 (312 aa)
initn: 1286 init1: 1204 opt: 1204 Z-score: 839.9 bits: 163.6 E(32554): 1.8e-40
Smith-Waterman score: 1235; 64.1% identity (77.7% similar) in 309 aa overlap (3-305:35-307)
10 20 30
pF1KE0 MSSPRAVVQLGKA--QPAGEELATANQTAQQP
.: :.: .... ::. :. .: ...
CCDS82 ENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPT----AAPGQKVMEN
10 20 30 40 50 60
40 50 60 70 80
pF1KE0 SS--PAM--RRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEH
:: : . :..:.::::::::::: :: :.
CCDS82 SSGTPDILTRHFTIDDFEIGRPLGK------------------ALLCLWP----------
70 80 90
90 100 110 120 130 140
pF1KE0 QLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATI
: . .:::::::::::.: ::.::::::::::::::::::: .::::::::
CCDS82 ----EASSVSSPSHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATI
100 110 120 130 140
150 160 170 180 190 200
pF1KE0 IEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKTMCGTLDYL
.::::::: ::: ::::::::::::::::..::.::::::::::.:::::::::::::::
CCDS82 MEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYL
150 160 170 180 190 200
210 220 230 240 250 260
pF1KE0 PPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGA
:::::::: ..:::::::::::::::::: ::::::::.::::::.:::..:: :.:.::
CCDS82 PPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGA
210 220 230 240 250 260
270 280 290 300
pF1KE0 RDLISRLLRYQPLERLPLAQILKHPWVQAHSRRVLPPCAQMAS
.::::.:::..: :::::::. ::::.:.::::::: :
CCDS82 QDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
270 280 290 300 310
>>CCDS60974.1 SIK3 gene_id:23387|Hs108|chr11 (1261 aa)
initn: 598 init1: 274 opt: 618 Z-score: 437.0 bits: 91.0 E(32554): 5e-18
Smith-Waterman score: 618; 34.3% identity (63.4% similar) in 303 aa overlap (15-307:35-336)
10 20 30 40
pF1KE0 MSSPRAVVQLGKAQPAGEELATANQTAQQPSSPAMRR---LTVD
::. .. .: .:: : .
CCDS60 AASGAGGAAGAGTGGAGPAGRLLPPPAPGSPAAPAAVSPAAGQPRPPAPASRGPMPARIG
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 DFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHP
.:: : .:::.:. : : .. ::.:.. :.:...:.:. .. ::..:. : ::
CCDS60 YYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENLK-KIFREVQIMKMLCHP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 NILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKK
.:.:::. .. : .::. ::: ::.. .: .. :... ..... :. .:: ..
CCDS60 HIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRN
130 140 150 160 170 180
170 180 190 200 210
pF1KE0 VIHRDIKPENLLLGFRGEVKIADFGWS-VHTPSLRRKTMCGTLDYLPPEMIEGRTYD-EK
..:::.: ::::: ..::::::.: . ::. :: ::. : ::..::. :: :
CCDS60 IVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPK
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE0 VDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQPL
::.: .::. : :. : ::.... .. :.:. :.:. : . :: ..: .:
CCDS60 VDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPN
250 260 270 280 290 300
280 290 300
pF1KE0 ERLPLAQILKHPWVQ-----AHSRRVLPPCAQMAS
.:: . :: :: :.. . :.. : :.
CCDS60 KRLSMEQICKHKWMKLGDADPNFDRLIAECQQLKEERQVDPLNEDVLLAMEDMGLDKEQT
310 320 330 340 350 360
CCDS60 LQAEQAGTAMNISVPQVQLINPENQIVEPDGTLNLDSDEGEEPSPEALVRYLSMRRHTVG
370 380 390 400 410 420
>>CCDS8379.2 SIK3 gene_id:23387|Hs108|chr11 (1321 aa)
initn: 598 init1: 274 opt: 618 Z-score: 436.8 bits: 91.0 E(32554): 5.2e-18
Smith-Waterman score: 618; 34.3% identity (63.4% similar) in 303 aa overlap (15-307:35-336)
10 20 30 40
pF1KE0 MSSPRAVVQLGKAQPAGEELATANQTAQQPSSPAMRR---LTVD
::. .. .: .:: : .
CCDS83 AASGAGGAAGAGTGGAGPAGRLLPPPAPGSPAAPAAVSPAAGQPRPPAPASRGPMPARIG
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 DFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHP
.:: : .:::.:. : : .. ::.:.. :.:...:.:. .. ::..:. : ::
CCDS83 YYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENLK-KIFREVQIMKMLCHP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 NILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKK
.:.:::. .. : .::. ::: ::.. .: .. :... ..... :. .:: ..
CCDS83 HIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRN
130 140 150 160 170 180
170 180 190 200 210
pF1KE0 VIHRDIKPENLLLGFRGEVKIADFGWS-VHTPSLRRKTMCGTLDYLPPEMIEGRTYD-EK
..:::.: ::::: ..::::::.: . ::. :: ::. : ::..::. :: :
CCDS83 IVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPK
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE0 VDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQPL
::.: .::. : :. : ::.... .. :.:. :.:. : . :: ..: .:
CCDS83 VDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPN
250 260 270 280 290 300
280 290 300
pF1KE0 ERLPLAQILKHPWVQ-----AHSRRVLPPCAQMAS
.:: . :: :: :.. . :.. : :.
CCDS83 KRLSMEQICKHKWMKLGDADPNFDRLIAECQQLKEERQVDPLNEDVLLAMEDMGLDKEQT
310 320 330 340 350 360
CCDS83 LQSLRSDAYDHYSAIYSLLCDRHKRHKTLRLGALPSMPRALAFQAPVNIQAEQAGTAMNI
370 380 390 400 410 420
309 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 03:00:27 2016 done: Sat Nov 5 03:00:28 2016
Total Scan time: 2.570 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]