Result of FASTA (omim) for
pF1KE0724
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0724, 415 aa
1>>>pF1KE0724 415 - 415 aa - 415 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.0523+/-0.000555; mu= -5.4519+/- 0.033
mean_var=615.4964+/-150.305, 0's: 0 Z-trim(116.0): 98 B-trim: 0 in 0/51
Lambda= 0.051697
statistics sampled from 26710 (26796) to 26710 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.672), E-opt: 0.2 (0.314), width: 16
Scan time: 8.680
The best scores are: opt bits E(85289)
NP_001310 (OMIM: 602214) casein kinase I isoform g ( 415) 2819 226.0 1.3e-58
XP_005259557 (OMIM: 602214) PREDICTED: casein kina ( 440) 2458 199.1 1.7e-50
XP_016881787 (OMIM: 602214) PREDICTED: casein kina ( 367) 2399 194.6 3.4e-49
XP_005271953 (OMIM: 604253) PREDICTED: casein kina ( 416) 2366 192.2 2e-48
XP_016864559 (OMIM: 604253) PREDICTED: casein kina ( 415) 2348 190.9 5e-48
NP_001316535 (OMIM: 606274) casein kinase I isofor ( 422) 2269 185.0 3e-46
NP_071331 (OMIM: 606274) casein kinase I isoform g ( 422) 2269 185.0 3e-46
XP_016864558 (OMIM: 604253) PREDICTED: casein kina ( 424) 2245 183.2 1e-45
XP_005271952 (OMIM: 604253) PREDICTED: casein kina ( 424) 2245 183.2 1e-45
NP_001257501 (OMIM: 604253) casein kinase I isofor ( 424) 2245 183.2 1e-45
NP_001026982 (OMIM: 604253) casein kinase I isofor ( 423) 2227 181.9 2.6e-45
NP_001316536 (OMIM: 606274) casein kinase I isofor ( 438) 2178 178.3 3.4e-44
XP_005259555 (OMIM: 602214) PREDICTED: casein kina ( 445) 2172 177.8 4.6e-44
XP_005259556 (OMIM: 602214) PREDICTED: casein kina ( 445) 2172 177.8 4.6e-44
XP_016881786 (OMIM: 602214) PREDICTED: casein kina ( 445) 2172 177.8 4.6e-44
XP_016864556 (OMIM: 604253) PREDICTED: casein kina ( 441) 2131 174.8 3.8e-43
XP_016864557 (OMIM: 604253) PREDICTED: casein kina ( 440) 2113 173.4 9.7e-43
XP_005271948 (OMIM: 604253) PREDICTED: casein kina ( 456) 2052 168.9 2.3e-41
XP_005259558 (OMIM: 602214) PREDICTED: casein kina ( 392) 2038 167.7 4.4e-41
XP_005271951 (OMIM: 604253) PREDICTED: casein kina ( 447) 2034 167.5 5.8e-41
NP_004375 (OMIM: 604253) casein kinase I isoform g ( 447) 2034 167.5 5.8e-41
XP_005271949 (OMIM: 604253) PREDICTED: casein kina ( 455) 2034 167.5 5.9e-41
NP_001038188 (OMIM: 604253) casein kinase I isofor ( 455) 2034 167.5 5.9e-41
XP_016864553 (OMIM: 604253) PREDICTED: casein kina ( 449) 2010 165.7 2e-40
NP_001316534 (OMIM: 606274) casein kinase I isofor ( 475) 2003 165.3 3e-40
XP_016864555 (OMIM: 604253) PREDICTED: casein kina ( 448) 1992 164.4 5.1e-40
XP_016864554 (OMIM: 604253) PREDICTED: casein kina ( 448) 1992 164.4 5.1e-40
NP_001257502 (OMIM: 604253) casein kinase I isofor ( 348) 1890 156.6 8.8e-38
XP_016864552 (OMIM: 604253) PREDICTED: casein kina ( 473) 1817 151.4 4.5e-36
XP_016864548 (OMIM: 604253) PREDICTED: casein kina ( 481) 1817 151.4 4.5e-36
XP_016864546 (OMIM: 604253) PREDICTED: casein kina ( 481) 1817 151.4 4.5e-36
XP_016864549 (OMIM: 604253) PREDICTED: casein kina ( 481) 1817 151.4 4.5e-36
XP_016864547 (OMIM: 604253) PREDICTED: casein kina ( 481) 1817 151.4 4.5e-36
XP_016864551 (OMIM: 604253) PREDICTED: casein kina ( 480) 1799 150.1 1.1e-35
XP_016864550 (OMIM: 604253) PREDICTED: casein kina ( 480) 1799 150.1 1.1e-35
NP_001257503 (OMIM: 604253) casein kinase I isofor ( 311) 1667 139.9 8.4e-33
NP_620693 (OMIM: 600864,615224) casein kinase I is ( 409) 1208 105.9 2e-22
NP_001884 (OMIM: 600864,615224) casein kinase I is ( 415) 1208 105.9 2e-22
XP_005256394 (OMIM: 600864,615224) PREDICTED: case ( 427) 1208 105.9 2e-22
XP_005256393 (OMIM: 600864,615224) PREDICTED: case ( 450) 1208 105.9 2.1e-22
NP_689407 (OMIM: 600863) casein kinase I isoform e ( 416) 1203 105.5 2.6e-22
NP_001885 (OMIM: 600863) casein kinase I isoform e ( 416) 1203 105.5 2.6e-22
NP_001258670 (OMIM: 600505) casein kinase I isofor ( 325) 1099 97.6 4.9e-20
NP_001883 (OMIM: 600505) casein kinase I isoform a ( 337) 1099 97.6 4.9e-20
XP_016879688 (OMIM: 600864,615224) PREDICTED: case ( 393) 1014 91.4 4.3e-18
NP_001258671 (OMIM: 600505) casein kinase I isofor ( 276) 619 61.7 2.7e-09
NP_001020276 (OMIM: 600505) casein kinase I isofor ( 365) 619 61.9 3.1e-09
NP_775771 (OMIM: 604432,611695) tau-tubulin kinase (1244) 550 57.6 2.1e-07
XP_005254230 (OMIM: 604432,611695) PREDICTED: tau- (1175) 468 51.4 1.4e-05
XP_006720466 (OMIM: 604432,611695) PREDICTED: tau- (1175) 468 51.4 1.4e-05
>>NP_001310 (OMIM: 602214) casein kinase I isoform gamma (415 aa)
initn: 2819 init1: 2819 opt: 2819 Z-score: 1173.1 bits: 226.0 E(85289): 1.3e-58
Smith-Waterman score: 2819; 100.0% identity (100.0% similar) in 415 aa overlap (1-415:1-415)
10 20 30 40 50 60
pF1KE0 MDFDKKGGKGETEEGRRMSKAGGGRSSHGIRSSGTSSGVLMVGPNFRVGKKIGCGNFGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDFDKKGGKGETEEGRRMSKAGGGRSSHGIRSSGTSSGVLMVGPNFRVGKKIGCGNFGEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 RLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATEGVPQVYYFGPCGKYNAMVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATEGVPQVYYFGPCGKYNAMVLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 QHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 MFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 EKPDYDYLRKLFTDLFDRSGFVFDYEYDWAGKPLPTPIGTVHTDLPSQPQLRDKTQPHSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKPDYDYLRKLFTDLFDRSGFVFDYEYDWAGKPLPTPIGTVHTDLPSQPQLRDKTQPHSK
310 320 330 340 350 360
370 380 390 400 410
pF1KE0 NQALNSTNGELNADDPTAGHSNAPITAPAEVEVADETKCCCFFKRRKRKSLQRHK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQALNSTNGELNADDPTAGHSNAPITAPAEVEVADETKCCCFFKRRKRKSLQRHK
370 380 390 400 410
>>XP_005259557 (OMIM: 602214) PREDICTED: casein kinase I (440 aa)
initn: 2457 init1: 2457 opt: 2458 Z-score: 1027.3 bits: 199.1 E(85289): 1.7e-50
Smith-Waterman score: 2759; 94.3% identity (94.3% similar) in 440 aa overlap (1-415:1-440)
10 20 30 40 50 60
pF1KE0 MDFDKKGGKGETEEGRRMSKAGGGRSSHGIRSSGTSSGVLMVGPNFRVGKKIGCGNFGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDFDKKGGKGETEEGRRMSKAGGGRSSHGIRSSGTSSGVLMVGPNFRVGKKIGCGNFGEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 RLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATEGVPQVYYFGPCGKYNAMVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATEGVPQVYYFGPCGKYNAMVLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 QHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 MFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 EKPDYDYLRKLFTDLFDRSGFVFDYEYDWAGKPLPTPIGTVHTDLPSQPQLRDKTQPHSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKPDYDYLRKLFTDLFDRSGFVFDYEYDWAGKPLPTPIGTVHTDLPSQPQLRDKTQPHSK
310 320 330 340 350 360
370 380 390
pF1KE0 NQ-------------------------ALNSTNGELNADDPTAGHSNAPITAPAEVEVAD
:: :::::::::::::::::::::::::::::::::
XP_005 NQVRPGRDRPPQGGAWAASVTPYCPHQALNSTNGELNADDPTAGHSNAPITAPAEVEVAD
370 380 390 400 410 420
400 410
pF1KE0 ETKCCCFFKRRKRKSLQRHK
::::::::::::::::::::
XP_005 ETKCCCFFKRRKRKSLQRHK
430 440
>>XP_016881787 (OMIM: 602214) PREDICTED: casein kinase I (367 aa)
initn: 2399 init1: 2399 opt: 2399 Z-score: 1004.3 bits: 194.6 E(85289): 3.4e-49
Smith-Waterman score: 2399; 100.0% identity (100.0% similar) in 353 aa overlap (63-415:15-367)
40 50 60 70 80 90
pF1KE0 SGTSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRF
::::::::::::::::::::::::::::::
XP_016 MDRWMVAVRMDRVAGKNLYTNEYVAIKLEPIKSRAPQLHLEYRF
10 20 30 40
100 110 120 130 140 150
pF1KE0 YKQLSATEGVPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKQLSATEGVPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITR
50 60 70 80 90 100
160 170 180 190 200 210
pF1KE0 MEYVHTKSLIYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEYVHTKSLIYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKSL
110 120 130 140 150 160
220 230 240 250 260 270
pF1KE0 TGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKR
170 180 190 200 210 220
280 290 300 310 320 330
pF1KE0 ATPIEVLCENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGFVFDYEYDWAGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATPIEVLCENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGFVFDYEYDWAGK
230 240 250 260 270 280
340 350 360 370 380 390
pF1KE0 PLPTPIGTVHTDLPSQPQLRDKTQPHSKNQALNSTNGELNADDPTAGHSNAPITAPAEVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLPTPIGTVHTDLPSQPQLRDKTQPHSKNQALNSTNGELNADDPTAGHSNAPITAPAEVE
290 300 310 320 330 340
400 410
pF1KE0 VADETKCCCFFKRRKRKSLQRHK
:::::::::::::::::::::::
XP_016 VADETKCCCFFKRRKRKSLQRHK
350 360
>>XP_005271953 (OMIM: 604253) PREDICTED: casein kinase I (416 aa)
initn: 2324 init1: 1997 opt: 2366 Z-score: 990.5 bits: 192.2 E(85289): 2e-48
Smith-Waterman score: 2366; 84.0% identity (94.0% similar) in 418 aa overlap (4-415:3-416)
10 20 30 40 50
pF1KE0 MDFDKKGGKGETEEGRRMSKAGGGRSSHGIRSSGTSS-GVLMVGPNFRVGKKIGCGNFGE
.:: : .... ::.. .: ::.:. :..:.:: ::::::::::::::::::::::
XP_005 MENKKKDKDKSDD--RMARPSG-RSGHNTRGTGSSSSGVLMVGPNFRVGKKIGCGNFGE
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATEGVPQVYYFGPCGKYNAMVL
:::::::::::::::::::.:::::::::::::::::.. .:.:::::::::::::::::
XP_005 LRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 ELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTK
::::::::::::::::::.::::::::::::.::::::.:.::::::::::::.::::.:
XP_005 ELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 RQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALG
:..::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 HMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 FEKPDYDYLRKLFTDLFDRSGFVFDYEYDWAGKPLPTPIGTVHTD--LPSQ---PQLRDK
:::::::::::::::::::.:..::::::: :: ::::.:.:. : : :. : :::
XP_005 FEKPDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDK
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE0 TQPHSKNQALNSTNGELNADDPTAGHSNAPITAPAEVEVADETKCCCFFKRRKRKSLQRH
: .::::...:::::::.::::::.::::::::.:::: :::::::::::::::..:::
XP_005 MQ-QSKNQVVSSTNGELNTDDPTAGRSNAPITAPTEVEVMDETKCCCFFKRRKRKTIQRH
360 370 380 390 400 410
pF1KE0 K
:
XP_005 K
>>XP_016864559 (OMIM: 604253) PREDICTED: casein kinase I (415 aa)
initn: 1958 init1: 1631 opt: 2348 Z-score: 983.2 bits: 190.9 E(85289): 5e-48
Smith-Waterman score: 2348; 83.7% identity (93.8% similar) in 418 aa overlap (4-415:3-415)
10 20 30 40 50
pF1KE0 MDFDKKGGKGETEEGRRMSKAGGGRSSHGIRSSGTSS-GVLMVGPNFRVGKKIGCGNFGE
.:: : .... ::.. .: ::.:. :..:.:: ::::::::::::::::::::::
XP_016 MENKKKDKDKSDD--RMARPSG-RSGHNTRGTGSSSSGVLMVGPNFRVGKKIGCGNFGE
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATEGVPQVYYFGPCGKYNAMVL
:::::::::::::::::::.:::::::::::::::::.. .:.:::::::::::::::::
XP_016 LRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 ELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTK
::::::::::::::::::.::::::::::::.::::::.:.::::::::::::.::::.:
XP_016 ELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 RQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALG
:..::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 HMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDF
:::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::
XP_016 HMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPE-MATYLRYVRRLDF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 FEKPDYDYLRKLFTDLFDRSGFVFDYEYDWAGKPLPTPIGTVHTD--LPSQ---PQLRDK
:::::::::::::::::::.:..::::::: :: ::::.:.:. : : :. : :::
XP_016 FEKPDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDK
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE0 TQPHSKNQALNSTNGELNADDPTAGHSNAPITAPAEVEVADETKCCCFFKRRKRKSLQRH
: .::::...:::::::.::::::.::::::::.:::: :::::::::::::::..:::
XP_016 MQ-QSKNQVVSSTNGELNTDDPTAGRSNAPITAPTEVEVMDETKCCCFFKRRKRKTIQRH
360 370 380 390 400 410
pF1KE0 K
:
XP_016 K
>>NP_001316535 (OMIM: 606274) casein kinase I isoform ga (422 aa)
initn: 2269 init1: 1558 opt: 2269 Z-score: 951.3 bits: 185.0 E(85289): 3e-46
Smith-Waterman score: 2269; 80.0% identity (91.8% similar) in 416 aa overlap (11-415:7-422)
10 20 30 40 50
pF1KE0 MDFDKKGGKGETEEGRRMSKAGGGRSSHGIRSSGTSS--GVLMVGPNFRVGKKIGCGNFG
: .: .: .: . ::.: : ::.:: :::::::::::::::::::::
NP_001 MDHPSREKDERQRTTKPMAQRSAHCSRPSGSSSSSGVLMVGPNFRVGKKIGCGNFG
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 ELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQL-SATEGVPQVYYFGPCGKYNAM
:::::::::::::::::::::::::::::::::::::: :: ::.:::::::::::::::
NP_001 ELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGEGLPQVYYFGPCGKYNAM
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 VLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPG
::::::::::::::::::::::::::::::::..::::::.:.::::::::::::.:: :
NP_001 VLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 TKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEA
.:..:.::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 LGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRL
::::::::::::::::::::::::::::::::::: ::::.:::::::::::::::::::
NP_001 LGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 DFFEKPDYDYLRKLFTDLFDRSGFVFDYEYDWAGKPLPTPIGTVHTDLPSQPQLRD----
::::::::.::: ::::::...:..::: :::.:.:.:::.:.::.: .. :.
NP_001 DFFEKPDYEYLRTLFTDLFEKKGYTFDYAYDWVGRPIPTPVGSVHVDSGASAITRESHTH
300 310 320 330 340 350
360 370 380 390 400
pF1KE0 KTQPHS----KNQALNSTNGELNADDPTAGHSNAPITAPAEVEVADETKCCCFFKRRKRK
. .: . .::...:::::::.::::..:::::::: :::::..:.::::::::...:
NP_001 RDRPSQQQPLRNQVVSSTNGELNVDDPTGAHSNAPITAHAEVEVVEEAKCCCFFKRKRKK
360 370 380 390 400 410
410
pF1KE0 SLQRHK
. ::::
NP_001 TAQRHK
420
>>NP_071331 (OMIM: 606274) casein kinase I isoform gamma (422 aa)
initn: 2269 init1: 1558 opt: 2269 Z-score: 951.3 bits: 185.0 E(85289): 3e-46
Smith-Waterman score: 2269; 80.0% identity (91.8% similar) in 416 aa overlap (11-415:7-422)
10 20 30 40 50
pF1KE0 MDFDKKGGKGETEEGRRMSKAGGGRSSHGIRSSGTSS--GVLMVGPNFRVGKKIGCGNFG
: .: .: .: . ::.: : ::.:: :::::::::::::::::::::
NP_071 MDHPSREKDERQRTTKPMAQRSAHCSRPSGSSSSSGVLMVGPNFRVGKKIGCGNFG
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 ELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQL-SATEGVPQVYYFGPCGKYNAM
:::::::::::::::::::::::::::::::::::::: :: ::.:::::::::::::::
NP_071 ELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGEGLPQVYYFGPCGKYNAM
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 VLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPG
::::::::::::::::::::::::::::::::..::::::.:.::::::::::::.:: :
NP_071 VLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 TKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEA
.:..:.::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 NKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 LGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRL
::::::::::::::::::::::::::::::::::: ::::.:::::::::::::::::::
NP_071 LGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 DFFEKPDYDYLRKLFTDLFDRSGFVFDYEYDWAGKPLPTPIGTVHTDLPSQPQLRD----
::::::::.::: ::::::...:..::: :::.:.:.:::.:.::.: .. :.
NP_071 DFFEKPDYEYLRTLFTDLFEKKGYTFDYAYDWVGRPIPTPVGSVHVDSGASAITRESHTH
300 310 320 330 340 350
360 370 380 390 400
pF1KE0 KTQPHS----KNQALNSTNGELNADDPTAGHSNAPITAPAEVEVADETKCCCFFKRRKRK
. .: . .::...:::::::.::::..:::::::: :::::..:.::::::::...:
NP_071 RDRPSQQQPLRNQVVSSTNGELNVDDPTGAHSNAPITAHAEVEVVEEAKCCCFFKRKRKK
360 370 380 390 400 410
410
pF1KE0 SLQRHK
. ::::
NP_071 TAQRHK
420
>>XP_016864558 (OMIM: 604253) PREDICTED: casein kinase I (424 aa)
initn: 2316 init1: 1997 opt: 2245 Z-score: 941.6 bits: 183.2 E(85289): 1e-45
Smith-Waterman score: 2334; 82.2% identity (92.3% similar) in 426 aa overlap (4-415:3-424)
10 20 30 40 50
pF1KE0 MDFDKKGGKGETEEGRRMSKAGGGRSSHGIRSSGTSS-GVLMVGPNFRVGKKIGCGNFGE
.:: : .... ::.. .: ::.:. :..:.:: ::::::::::::::::::::::
XP_016 MENKKKDKDKSDD--RMARPSG-RSGHNTRGTGSSSSGVLMVGPNFRVGKKIGCGNFGE
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATEGVPQVYYFGPCGKYNAMVL
:::::::::::::::::::.:::::::::::::::::.. .:.:::::::::::::::::
XP_016 LRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 ELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTK
::::::::::::::::::.::::::::::::.::::::.:.::::::::::::.::::.:
XP_016 ELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 RQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALG
:..::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 HMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 FEKPDYDYLRKLFTDLFDRSGFVFDYEYDWAGKPLPTPIGTVHTD--LPSQ---PQLRDK
:::::::::::::::::::.:..::::::: :: ::::.:.:. : : :. : :::
XP_016 FEKPDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDK
300 310 320 330 340 350
360 370 380 390 400
pF1KE0 TQPHSKNQALNSTNGELNADDPTAGHSNAPITAPAEVEVADETKC--------CCFFKRR
: .::::...:::::::.::::::.::::::::.:::: :::.: :::::::
XP_016 MQ-QSKNQVVSSTNGELNTDDPTAGRSNAPITAPTEVEVMDETNCQKVLNMWCCCFFKRR
360 370 380 390 400 410
410
pF1KE0 KRKSLQRHK
:::..::::
XP_016 KRKTIQRHK
420
>>XP_005271952 (OMIM: 604253) PREDICTED: casein kinase I (424 aa)
initn: 2316 init1: 1997 opt: 2245 Z-score: 941.6 bits: 183.2 E(85289): 1e-45
Smith-Waterman score: 2334; 82.2% identity (92.3% similar) in 426 aa overlap (4-415:3-424)
10 20 30 40 50
pF1KE0 MDFDKKGGKGETEEGRRMSKAGGGRSSHGIRSSGTSS-GVLMVGPNFRVGKKIGCGNFGE
.:: : .... ::.. .: ::.:. :..:.:: ::::::::::::::::::::::
XP_005 MENKKKDKDKSDD--RMARPSG-RSGHNTRGTGSSSSGVLMVGPNFRVGKKIGCGNFGE
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATEGVPQVYYFGPCGKYNAMVL
:::::::::::::::::::.:::::::::::::::::.. .:.:::::::::::::::::
XP_005 LRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 ELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTK
::::::::::::::::::.::::::::::::.::::::.:.::::::::::::.::::.:
XP_005 ELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 RQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALG
:..::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 HMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 FEKPDYDYLRKLFTDLFDRSGFVFDYEYDWAGKPLPTPIGTVHTD--LPSQ---PQLRDK
:::::::::::::::::::.:..::::::: :: ::::.:.:. : : :. : :::
XP_005 FEKPDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDK
300 310 320 330 340 350
360 370 380 390 400
pF1KE0 TQPHSKNQALNSTNGELNADDPTAGHSNAPITAPAEVEVADETKC--------CCFFKRR
: .::::...:::::::.::::::.::::::::.:::: :::.: :::::::
XP_005 MQ-QSKNQVVSSTNGELNTDDPTAGRSNAPITAPTEVEVMDETNCQKVLNMWCCCFFKRR
360 370 380 390 400 410
410
pF1KE0 KRKSLQRHK
:::..::::
XP_005 KRKTIQRHK
420
>>NP_001257501 (OMIM: 604253) casein kinase I isoform ga (424 aa)
initn: 2316 init1: 1997 opt: 2245 Z-score: 941.6 bits: 183.2 E(85289): 1e-45
Smith-Waterman score: 2334; 82.2% identity (92.3% similar) in 426 aa overlap (4-415:3-424)
10 20 30 40 50
pF1KE0 MDFDKKGGKGETEEGRRMSKAGGGRSSHGIRSSGTSS-GVLMVGPNFRVGKKIGCGNFGE
.:: : .... ::.. .: ::.:. :..:.:: ::::::::::::::::::::::
NP_001 MENKKKDKDKSDD--RMARPSG-RSGHNTRGTGSSSSGVLMVGPNFRVGKKIGCGNFGE
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATEGVPQVYYFGPCGKYNAMVL
:::::::::::::::::::.:::::::::::::::::.. .:.:::::::::::::::::
NP_001 LRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 ELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTK
::::::::::::::::::.::::::::::::.::::::.:.::::::::::::.::::.:
NP_001 ELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 RQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALG
:..::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 HMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 FEKPDYDYLRKLFTDLFDRSGFVFDYEYDWAGKPLPTPIGTVHTD--LPSQ---PQLRDK
:::::::::::::::::::.:..::::::: :: ::::.:.:. : : :. : :::
NP_001 FEKPDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDK
300 310 320 330 340 350
360 370 380 390 400
pF1KE0 TQPHSKNQALNSTNGELNADDPTAGHSNAPITAPAEVEVADETKC--------CCFFKRR
: .::::...:::::::.::::::.::::::::.:::: :::.: :::::::
NP_001 MQ-QSKNQVVSSTNGELNTDDPTAGRSNAPITAPTEVEVMDETNCQKVLNMWCCCFFKRR
360 370 380 390 400 410
410
pF1KE0 KRKSLQRHK
:::..::::
NP_001 KRKTIQRHK
420
415 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 02:59:14 2016 done: Sat Nov 5 02:59:15 2016
Total Scan time: 8.680 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]