Result of FASTA (omim) for
pF1KE0707
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0707, 426 aa
1>>>pF1KE0707 426 - 426 aa - 426 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0210+/-0.000376; mu= 18.8191+/- 0.024
mean_var=91.2845+/-21.730, 0's: 0 Z-trim(113.5): 611 B-trim: 2413 in 2/51
Lambda= 0.134238
statistics sampled from 22039 (22847) to 22039 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.633), E-opt: 0.2 (0.268), width: 16
Scan time: 8.650
The best scores are: opt bits E(85289)
NP_006047 (OMIM: 604153) neuromedin-U receptor 1 [ ( 426) 2912 574.6 1.6e-163
XP_011508789 (OMIM: 604153) PREDICTED: neuromedin- ( 403) 2738 540.9 2.2e-153
XP_006712259 (OMIM: 604153) PREDICTED: neuromedin- ( 333) 2027 403.1 5.4e-112
XP_006712258 (OMIM: 604153) PREDICTED: neuromedin- ( 370) 2023 402.4 9.9e-112
XP_011508790 (OMIM: 604153) PREDICTED: neuromedin- ( 376) 2021 402.0 1.3e-111
XP_011508791 (OMIM: 604153) PREDICTED: neuromedin- ( 313) 2014 400.6 3e-111
XP_011535972 (OMIM: 605108) PREDICTED: neuromedin- ( 321) 898 184.4 3.5e-46
NP_064552 (OMIM: 605108) neuromedin-U receptor 2 [ ( 415) 898 184.6 4.1e-46
NP_002522 (OMIM: 162651) neurotensin receptor type ( 418) 621 130.9 5.9e-30
XP_011527129 (OMIM: 162651) PREDICTED: neurotensin ( 336) 502 107.8 4.4e-23
XP_011515565 (OMIM: 188545) PREDICTED: thyrotropin ( 398) 448 97.4 6.9e-20
NP_003292 (OMIM: 188545) thyrotropin-releasing hor ( 398) 448 97.4 6.9e-20
NP_004113 (OMIM: 601898) growth hormone secretagog ( 289) 425 92.8 1.2e-18
NP_940799 (OMIM: 601898) growth hormone secretagog ( 366) 425 92.9 1.4e-18
NP_001498 (OMIM: 602885) motilin receptor [Homo sa ( 412) 407 89.5 1.7e-17
XP_006711940 (OMIM: 605538) PREDICTED: neurotensin ( 319) 391 86.3 1.3e-16
XP_006711939 (OMIM: 605538) PREDICTED: neurotensin ( 322) 391 86.3 1.3e-16
XP_016859227 (OMIM: 605538) PREDICTED: neurotensin ( 339) 391 86.3 1.3e-16
NP_036476 (OMIM: 605538) neurotensin receptor type ( 410) 391 86.4 1.5e-16
NP_444264 (OMIM: 607449) neuropeptide FF receptor ( 420) 388 85.8 2.3e-16
NP_001138228 (OMIM: 607449) neuropeptide FF recept ( 423) 388 85.8 2.3e-16
NP_004876 (OMIM: 607449) neuropeptide FF receptor ( 522) 388 85.9 2.6e-16
XP_005246213 (OMIM: 605538) PREDICTED: neurotensin ( 250) 353 78.8 1.7e-14
NP_000721 (OMIM: 118444) cholecystokinin receptor ( 428) 341 76.7 1.3e-13
NP_000862 (OMIM: 601109) 5-hydroxytryptamine recep ( 440) 331 74.8 4.9e-13
NP_872588 (OMIM: 602548) nociceptin receptor isofo ( 370) 328 74.1 6.5e-13
XP_016883343 (OMIM: 602548) PREDICTED: nociceptin ( 370) 328 74.1 6.5e-13
NP_000904 (OMIM: 602548) nociceptin receptor isofo ( 370) 328 74.1 6.5e-13
NP_001186948 (OMIM: 602548) nociceptin receptor is ( 370) 328 74.1 6.5e-13
XP_016883341 (OMIM: 602548) PREDICTED: nociceptin ( 388) 328 74.1 6.7e-13
XP_016883342 (OMIM: 602548) PREDICTED: nociceptin ( 388) 328 74.1 6.7e-13
XP_011527130 (OMIM: 602548) PREDICTED: nociceptin ( 388) 328 74.1 6.7e-13
NP_001305782 (OMIM: 602548) nociceptin receptor is ( 399) 328 74.2 6.9e-13
NP_001043 (OMIM: 182454) somatostatin receptor typ ( 388) 324 73.4 1.2e-12
NP_000015 (OMIM: 109690,600807,601665) beta-2 adre ( 413) 323 73.2 1.4e-12
NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 319 72.4 2.2e-12
NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409) 319 72.4 2.3e-12
NP_001048 (OMIM: 162321) substance-K receptor [Hom ( 398) 317 72.0 3e-12
NP_000667 (OMIM: 600446) adenosine receptor A2b [H ( 332) 316 71.8 3e-12
NP_795344 (OMIM: 118445) gastrin/cholecystokinin t ( 447) 309 70.5 9.5e-12
XP_005253267 (OMIM: 118445) PREDICTED: gastrin/cho ( 516) 309 70.6 1e-11
NP_001718 (OMIM: 300107) bombesin receptor subtype ( 399) 306 69.9 1.3e-11
NP_001265616 (OMIM: 182453) somatostatin receptor ( 418) 306 69.9 1.4e-11
XP_016884412 (OMIM: 182453) PREDICTED: somatostati ( 418) 306 69.9 1.4e-11
NP_001042 (OMIM: 182453) somatostatin receptor typ ( 418) 306 69.9 1.4e-11
XP_011528651 (OMIM: 182453) PREDICTED: somatostati ( 418) 306 69.9 1.4e-11
XP_016884413 (OMIM: 182453) PREDICTED: somatostati ( 418) 306 69.9 1.4e-11
XP_006724374 (OMIM: 182453) PREDICTED: somatostati ( 418) 306 69.9 1.4e-11
XP_005261778 (OMIM: 182453) PREDICTED: somatostati ( 418) 306 69.9 1.4e-11
NP_001305783 (OMIM: 602548) nociceptin receptor is ( 365) 302 69.1 2.1e-11
>>NP_006047 (OMIM: 604153) neuromedin-U receptor 1 [Homo (426 aa)
initn: 2912 init1: 2912 opt: 2912 Z-score: 3056.6 bits: 574.6 E(85289): 1.6e-163
Smith-Waterman score: 2912; 100.0% identity (100.0% similar) in 426 aa overlap (1-426:1-426)
10 20 30 40 50 60
pF1KE0 MTPLCLNCSVLPGDLYPGGARNPMACNGSAARGHFDPEDLNLTDEALRLKYLGPQQTELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MTPLCLNCSVLPGDLYPGGARNPMACNGSAARGHFDPEDLNLTDEALRLKYLGPQQTELF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 MPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 MWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 VLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALLFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALLFF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 CLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 CLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 VLVVVFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSAANPVLYSLMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VLVVVFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSAANPVLYSLMS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 SRFRETFQEALCLGACCHRLRPRHSSHSLSRMTTGSTLCDVGSLGSWVHPLAGNDGPEAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SRFRETFQEALCLGACCHRLRPRHSSHSLSRMTTGSTLCDVGSLGSWVHPLAGNDGPEAQ
370 380 390 400 410 420
pF1KE0 QETDPS
::::::
NP_006 QETDPS
>>XP_011508789 (OMIM: 604153) PREDICTED: neuromedin-U re (403 aa)
initn: 2738 init1: 2738 opt: 2738 Z-score: 2874.8 bits: 540.9 E(85289): 2.2e-153
Smith-Waterman score: 2738; 100.0% identity (100.0% similar) in 403 aa overlap (24-426:1-403)
10 20 30 40 50 60
pF1KE0 MTPLCLNCSVLPGDLYPGGARNPMACNGSAARGHFDPEDLNLTDEALRLKYLGPQQTELF
:::::::::::::::::::::::::::::::::::::
XP_011 MACNGSAARGHFDPEDLNLTDEALRLKYLGPQQTELF
10 20 30
70 80 90 100 110 120
pF1KE0 MPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYE
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE0 MWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRR
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE0 VLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALLFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALLFF
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE0 CLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLF
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE0 VLVVVFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSAANPVLYSLMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLVVVFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSAANPVLYSLMS
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE0 SRFRETFQEALCLGACCHRLRPRHSSHSLSRMTTGSTLCDVGSLGSWVHPLAGNDGPEAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRFRETFQEALCLGACCHRLRPRHSSHSLSRMTTGSTLCDVGSLGSWVHPLAGNDGPEAQ
340 350 360 370 380 390
pF1KE0 QETDPS
::::::
XP_011 QETDPS
400
>>XP_006712259 (OMIM: 604153) PREDICTED: neuromedin-U re (333 aa)
initn: 2020 init1: 2020 opt: 2027 Z-score: 2131.6 bits: 403.1 E(85289): 5.4e-112
Smith-Waterman score: 2027; 93.3% identity (95.4% similar) in 328 aa overlap (1-326:1-322)
10 20 30 40 50 60
pF1KE0 MTPLCLNCSVLPGDLYPGGARNPMACNGSAARGHFDPEDLNLTDEALRLKYLGPQQTELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MTPLCLNCSVLPGDLYPGGARNPMACNGSAARGHFDPEDLNLTDEALRLKYLGPQQTELF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 MPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 MWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 VLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALLFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALLFF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 CLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_006 CLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLW
250 260 270 280 290 300
310 320 330 340 350
pF1KE0 VLVVVFGICWAPFHADRVMWSVVSQ--WTDGLHLAFQHVHVISGIFFYLGSAANPVLYSL
: :. :: ..: ...: :
XP_006 VKEF-----WTLSTAD-IYWYMMDQASWVTQRGTCIWSK
310 320 330
>>XP_006712258 (OMIM: 604153) PREDICTED: neuromedin-U re (370 aa)
initn: 2021 init1: 2021 opt: 2023 Z-score: 2126.9 bits: 402.4 E(85289): 9.9e-112
Smith-Waterman score: 2023; 84.0% identity (90.4% similar) in 374 aa overlap (1-373:1-367)
10 20 30 40 50 60
pF1KE0 MTPLCLNCSVLPGDLYPGGARNPMACNGSAARGHFDPEDLNLTDEALRLKYLGPQQTELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MTPLCLNCSVLPGDLYPGGARNPMACNGSAARGHFDPEDLNLTDEALRLKYLGPQQTELF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 MPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 MWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 VLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALLFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALLFF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 CLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_006 CLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLY
250 260 270 280 290 300
310 320 330 340 350
pF1KE0 VLVVVFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGI-FFYLGSAANPVLYSLM
. :. : . :.: . .. ..:: .. . : :. :. :.:. .: :
XP_006 -FQVLDG--FLPIHQPPLSFTSF-LIPPSVHLPYS-ASVPEGVKEFWTLSTAD--IYWYM
310 320 330 340 350
360 370 380 390 400 410
pF1KE0 SSRFRETFQEALCLGACCHRLRPRHSSHSLSRMTTGSTLCDVGSLGSWVHPLAGNDGPEA
.. . :.. :.
XP_006 MDQASWVTQRGTCIWSK
360 370
>>XP_011508790 (OMIM: 604153) PREDICTED: neuromedin-U re (376 aa)
initn: 2021 init1: 2021 opt: 2021 Z-score: 2124.7 bits: 402.0 E(85289): 1.3e-111
Smith-Waterman score: 2021; 98.7% identity (99.3% similar) in 304 aa overlap (1-304:1-304)
10 20 30 40 50 60
pF1KE0 MTPLCLNCSVLPGDLYPGGARNPMACNGSAARGHFDPEDLNLTDEALRLKYLGPQQTELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTPLCLNCSVLPGDLYPGGARNPMACNGSAARGHFDPEDLNLTDEALRLKYLGPQQTELF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 MPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 MWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 VLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALLFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALLFF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 CLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_011 CLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 VLVVVFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSAANPVLYSLMS
:.
XP_011 FQVLDGFLPIHQPPLSFTSFLIPPSVHLPYSASVPEGEYTGIILPFSEKGLISLKIESPR
310 320 330 340 350 360
>>XP_011508791 (OMIM: 604153) PREDICTED: neuromedin-U re (313 aa)
initn: 2014 init1: 2014 opt: 2014 Z-score: 2118.3 bits: 400.6 E(85289): 3e-111
Smith-Waterman score: 2014; 100.0% identity (100.0% similar) in 299 aa overlap (1-299:1-299)
10 20 30 40 50 60
pF1KE0 MTPLCLNCSVLPGDLYPGGARNPMACNGSAARGHFDPEDLNLTDEALRLKYLGPQQTELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTPLCLNCSVLPGDLYPGGARNPMACNGSAARGHFDPEDLNLTDEALRLKYLGPQQTELF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 MPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 MWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 VLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALLFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALLFF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 CLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 VLVVVFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSAANPVLYSLMS
XP_011 ACEAWPPARHLLS
310
>>XP_011535972 (OMIM: 605108) PREDICTED: neuromedin-U re (321 aa)
initn: 1095 init1: 885 opt: 898 Z-score: 950.1 bits: 184.4 E(85289): 3.5e-46
Smith-Waterman score: 1088; 51.9% identity (80.5% similar) in 308 aa overlap (36-342:20-313)
10 20 30 40 50 60
pF1KE0 LNCSVLPGDLYPGGARNPMACNGSAARGHFDPEDLNLTDEALRLKYL-GPQQTELFMPIC
:: . .:.. : .: ::.....:.:.
XP_011 MSGMEKLQNASWIYQQKLEDPFQKHLNSTEEYLAFLCGPRRSHFFLPVS
10 20 30 40
70 80 90 100 110 120
pF1KE0 ATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYEMWHN
..:. :::::..:: :.:::::.:.::.:::::::::::::::::::.:.:::.::::.:
XP_011 VVYVPIFVVGVIGNVLVCLVILQHQAMKTPTNYYLFSLAVSDLLVLLLGMPLEVYEMWRN
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE0 YPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRRVLGA
::::.: ::::.: ::: ::.::.:..:..:::::::..::..:. . :: .. :.::
XP_011 YPFLFGPVGCYFKTALFETVCFASILSITTVSVERYVAILHPFRAKLQSTRRRALRILGI
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE0 VWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALLFFCLPM
:::...: ::::::.:::. . : . :: ::.: ...: .::...:.:..::. :::
XP_011 VWGFSVLFSLPNTSIHGIKFHYFPNGSLVPGSATCTVIKPMWIYNFIIQVTSFLFYLLPM
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE0 AIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLFVLVV
...:::: :..:::.... : .: :.: . :: ..:.:::::::.
XP_011 TVISVLYYLMALRLKKDKSLEADE----GNANIQR--PCR--------KSVNKMLFVLVL
230 240 250 260 270
310 320 330 340 350 360
pF1KE0 VFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSAANPVLYSLMSSRFR
::.::::::: ::...: : .:...: .:. :::.::
XP_011 VFAICWAPFHIDRLFFSFVEEWSESLAAVFNLVHVVSGKTLAGFGA
280 290 300 310 320
370 380 390 400 410 420
pF1KE0 ETFQEALCLGACCHRLRPRHSSHSLSRMTTGSTLCDVGSLGSWVHPLAGNDGPEAQQETD
>>NP_064552 (OMIM: 605108) neuromedin-U receptor 2 [Homo (415 aa)
initn: 1199 init1: 885 opt: 898 Z-score: 948.8 bits: 184.6 E(85289): 4.1e-46
Smith-Waterman score: 1209; 50.7% identity (79.9% similar) in 353 aa overlap (36-387:20-353)
10 20 30 40 50 60
pF1KE0 LNCSVLPGDLYPGGARNPMACNGSAARGHFDPEDLNLTDEALRLKYL-GPQQTELFMPIC
:: . .:.. : .: ::.....:.:.
NP_064 MSGMEKLQNASWIYQQKLEDPFQKHLNSTEEYLAFLCGPRRSHFFLPVS
10 20 30 40
70 80 90 100 110 120
pF1KE0 ATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYEMWHN
..:. :::::..:: :.:::::.:.::.:::::::::::::::::::.:.:::.::::.:
NP_064 VVYVPIFVVGVIGNVLVCLVILQHQAMKTPTNYYLFSLAVSDLLVLLLGMPLEVYEMWRN
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE0 YPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRRVLGA
::::.: ::::.: ::: ::.::.:..:..:::::::..::..:. . :: .. :.::
NP_064 YPFLFGPVGCYFKTALFETVCFASILSITTVSVERYVAILHPFRAKLQSTRRRALRILGI
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE0 VWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALLFFCLPM
:::...: ::::::.:::. . : . :: ::.: ...: .::...:.:..::. :::
NP_064 VWGFSVLFSLPNTSIHGIKFHYFPNGSLVPGSATCTVIKPMWIYNFIIQVTSFLFYLLPM
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE0 AIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLFVLVV
...:::: :..:::.... : .: :.: . :: ..:.:::::::.
NP_064 TVISVLYYLMALRLKKDKSLEADE----GNANIQR--PCR--------KSVNKMLFVLVL
230 240 250 260 270
310 320 330 340 350 360
pF1KE0 VFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSAANPVLYSLMSSRFR
::.::::::: ::...: : .:...: .:. :::.::.::::.::.::..:.:.: ::.
NP_064 VFAICWAPFHIDRLFFSFVEEWSESLAAVFNLVHVVSGVFFYLSSAVNPIIYNLLSRRFQ
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE0 ETFQEALCLGACCHRLRPRHSSHSLSRMTTGSTLCDVGSLGSWVHPLAGNDGPEAQQETD
.::... . :. ::.:
NP_064 AAFQNVI---SSFHK--QWHSQHDPQLPPAQRNIFLTECHFVELTEDIGPQFPCQSSMHN
340 350 360 370 380 390
>>NP_002522 (OMIM: 162651) neurotensin receptor type 1 [ (418 aa)
initn: 431 init1: 162 opt: 621 Z-score: 658.8 bits: 130.9 E(85289): 5.9e-30
Smith-Waterman score: 621; 31.5% identity (67.6% similar) in 340 aa overlap (63-391:66-397)
40 50 60 70 80 90
pF1KE0 GHFDPEDLNLTDEALRLKYLGPQQTELFMPICATYLLIFVVGAVGNGLTCLVILRHKAMR
. :.:: .::::.::: .: ... :.:...
NP_002 GNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQ
40 50 60 70 80 90
100 110 120 130 140
pF1KE0 T---PTNYYLFSLAVSDLLVLLVGLPLELYE-MWHNYPFLLGVGGCYFRTLLFEMVCLAS
. ..:.: :::.::::.::...:.:::. .: ..:. .: .:: .: . :.
NP_002 SLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYAT
100 110 120 130 140 150
150 160 170 180 190 200
pF1KE0 VLNVTALSVERYVAVVHPLQARSMVTRAHVRRVLGAVWGLAMLCSLPNTSLHGIRQLHVP
.:::..::::::.:. ::..:.....:..... ..:.: . : ..: : . .
NP_002 ALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMG--EQNRS
160 170 180 190 200 210
210 220 230 240 250 260
pF1KE0 CRGPVPDSAVCMLVRPRALYNMVVQTTALLFFCLPMAIMSVLYLLIGLRLRRERLLLMQE
: . :: . : ..:.:..... : .::...::: .:. .: ... :
NP_002 ADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKL---TVMVRQA
220 230 240 250 260 270
270 280 290 300 310 320
pF1KE0 AKGRGSAAARSRYTCRLQQHDRGRRQV----TKMLFVLVVVFGICWAPFHADRVMWSVVS
:. .. .... . . :: :. ...: ..:..: .:: :.:. :.:. .:
NP_002 AEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYIS
280 290 300 310 320 330
330 340 350 360 370 380
pF1KE0 --QWTDGLHLAFQHVHVISGIFFYLGSAANPVLYSLMSSRFRETFQEALCLGAC-CHRLR
::: :. ... ..... .::..:. ::.::.:.:. ::. : .: :: : :
NP_002 DEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATL---ACLCPVWR
340 350 360 370 380
390 400 410 420
pF1KE0 PRHSSHSLSRMTTGSTLCDVGSLGSWVHPLAGNDGPEAQQETDPS
:.. ..::
NP_002 RRRKRPAFSRKADSVSSNHTLSSNATRETLY
390 400 410
>>XP_011527129 (OMIM: 162651) PREDICTED: neurotensin rec (336 aa)
initn: 374 init1: 162 opt: 502 Z-score: 535.4 bits: 107.8 E(85289): 4.4e-23
Smith-Waterman score: 502; 31.3% identity (67.6% similar) in 275 aa overlap (63-327:66-335)
40 50 60 70 80 90
pF1KE0 GHFDPEDLNLTDEALRLKYLGPQQTELFMPICATYLLIFVVGAVGNGLTCLVILRHKAMR
. :.:: .::::.::: .: ... :.:...
XP_011 GNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQ
40 50 60 70 80 90
100 110 120 130 140
pF1KE0 T---PTNYYLFSLAVSDLLVLLVGLPLELYE-MWHNYPFLLGVGGCYFRTLLFEMVCLAS
. ..:.: :::.::::.::...:.:::. .: ..:. .: .:: .: . :.
XP_011 SLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYAT
100 110 120 130 140 150
150 160 170 180 190 200
pF1KE0 VLNVTALSVERYVAVVHPLQARSMVTRAHVRRVLGAVWGLAMLCSLPNTSLHGIRQLHVP
.:::..::::::.:. ::..:.....:..... ..:.: . : ..: : . .
XP_011 ALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMG--EQNRS
160 170 180 190 200 210
210 220 230 240 250 260
pF1KE0 CRGPVPDSAVCMLVRPRALYNMVVQTTALLFFCLPMAIMSVLYLLIGLRLRRERLLLMQE
: . :: . : ..:.:..... : .::...::: .:. .: ... :
XP_011 ADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLT---VMVRQA
220 230 240 250 260 270
270 280 290 300 310 320
pF1KE0 AKGRGSAAARSRYTCRLQQHDRGRRQV----TKMLFVLVVVFGICWAPFHADRVMWSVVS
:. .. .... . . :: :. ...: ..:..: .:: :.:. :.:. .:
XP_011 AEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYIS
280 290 300 310 320 330
330 340 350 360 370 380
pF1KE0 --QWTDGLHLAFQHVHVISGIFFYLGSAANPVLYSLMSSRFRETFQEALCLGACCHRLRP
:::
XP_011 DEQWTP
426 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 02:53:11 2016 done: Sat Nov 5 02:53:12 2016
Total Scan time: 8.650 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]