Result of FASTA (omim) for
pF1KE0702
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0702, 406 aa
1>>>pF1KE0702 406 - 406 aa - 406 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.2449+/-0.000542; mu= 3.4772+/- 0.032
mean_var=597.9945+/-138.597, 0's: 0 Z-trim(116.9): 1723 B-trim: 0 in 0/54
Lambda= 0.052448
statistics sampled from 26191 (28518) to 26191 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.7), E-opt: 0.2 (0.334), width: 16
Scan time: 8.070
The best scores are: opt bits E(85289)
NP_000285 (OMIM: 172471,613027) phosphorylase b ki ( 406) 2754 224.1 4.8e-58
NP_001165903 (OMIM: 172471,613027) phosphorylase b ( 374) 2463 202.0 2e-51
NP_006204 (OMIM: 172470) phosphorylase b kinase ga ( 387) 1717 145.6 2e-34
NP_001245389 (OMIM: 172470) phosphorylase b kinase ( 378) 1590 136.0 1.5e-31
NP_001245388 (OMIM: 172470) phosphorylase b kinase ( 419) 1317 115.4 2.6e-25
XP_005271829 (OMIM: 172470) PREDICTED: phosphoryla ( 309) 1310 114.6 3.3e-25
XP_016867816 (OMIM: 172470) PREDICTED: phosphoryla ( 326) 902 83.8 6.7e-16
XP_016867815 (OMIM: 172470) PREDICTED: phosphoryla ( 354) 902 83.9 6.9e-16
XP_016867814 (OMIM: 172470) PREDICTED: phosphoryla ( 378) 902 83.9 7.1e-16
XP_016867813 (OMIM: 172470) PREDICTED: phosphoryla ( 432) 902 84.0 7.5e-16
XP_016863321 (OMIM: 613166) PREDICTED: serine/thre ( 717) 650 65.4 5.2e-10
XP_005262843 (OMIM: 613166) PREDICTED: serine/thre ( 765) 650 65.4 5.3e-10
NP_001035350 (OMIM: 613166) serine/threonine-prote ( 766) 650 65.4 5.3e-10
NP_003647 (OMIM: 604998) calcium/calmodulin-depend ( 370) 644 64.4 5.3e-10
XP_005262842 (OMIM: 613166) PREDICTED: serine/thre ( 782) 650 65.5 5.4e-10
NP_001035351 (OMIM: 613166) serine/threonine-prote ( 783) 650 65.5 5.4e-10
XP_005265573 (OMIM: 604998) PREDICTED: calcium/cal ( 413) 644 64.5 5.6e-10
XP_016862843 (OMIM: 604998) PREDICTED: calcium/cal ( 326) 639 63.9 6.5e-10
XP_005265574 (OMIM: 604998) PREDICTED: calcium/cal ( 369) 639 64.0 6.9e-10
NP_208382 (OMIM: 613167) serine/threonine-protein ( 648) 641 64.6 7.9e-10
XP_011532469 (OMIM: 613167) PREDICTED: serine/thre ( 648) 641 64.6 7.9e-10
XP_016864167 (OMIM: 607708) PREDICTED: calcium/cal ( 477) 622 62.9 1.9e-09
NP_001308505 (OMIM: 607708) calcium/calmodulin-dep ( 477) 622 62.9 1.9e-09
XP_006724629 (OMIM: 300172,300422,300749) PREDICTE ( 885) 627 63.8 1.9e-09
NP_001119527 (OMIM: 300172,300422,300749) peripher ( 897) 627 63.8 1.9e-09
NP_001119526 (OMIM: 300172,300422,300749) peripher ( 898) 627 63.8 1.9e-09
NP_001308513 (OMIM: 607708) calcium/calmodulin-dep ( 491) 622 63.0 1.9e-09
NP_001308503 (OMIM: 607708) calcium/calmodulin-dep ( 498) 622 63.0 1.9e-09
XP_005272743 (OMIM: 300172,300422,300749) PREDICTE ( 920) 627 63.8 1.9e-09
NP_003679 (OMIM: 300172,300422,300749) peripheral ( 921) 627 63.8 1.9e-09
XP_011530592 (OMIM: 607708) PREDICTED: calcium/cal ( 509) 622 63.0 1.9e-09
NP_001308515 (OMIM: 607708) calcium/calmodulin-dep ( 511) 622 63.0 1.9e-09
NP_001308517 (OMIM: 607708) calcium/calmodulin-dep ( 512) 622 63.0 1.9e-09
XP_005263310 (OMIM: 607708) PREDICTED: calcium/cal ( 532) 622 63.0 2e-09
NP_001182344 (OMIM: 604742) serine/threonine-prote ( 422) 620 62.7 2e-09
NP_001182345 (OMIM: 604742) serine/threonine-prote ( 433) 620 62.7 2e-09
NP_001308510 (OMIM: 607708) calcium/calmodulin-dep ( 453) 620 62.7 2e-09
NP_742113 (OMIM: 607708) calcium/calmodulin-depend ( 478) 620 62.8 2.1e-09
NP_742126 (OMIM: 607708) calcium/calmodulin-depend ( 478) 620 62.8 2.1e-09
NP_742125 (OMIM: 607708) calcium/calmodulin-depend ( 478) 620 62.8 2.1e-09
NP_742127 (OMIM: 607708) calcium/calmodulin-depend ( 489) 620 62.8 2.1e-09
XP_011530593 (OMIM: 607708) PREDICTED: calcium/cal ( 489) 620 62.8 2.1e-09
NP_001308511 (OMIM: 607708) calcium/calmodulin-dep ( 489) 620 62.8 2.1e-09
NP_001308519 (OMIM: 607708) calcium/calmodulin-dep ( 492) 620 62.8 2.1e-09
NP_742112 (OMIM: 607708) calcium/calmodulin-depend ( 492) 620 62.8 2.1e-09
NP_001308518 (OMIM: 607708) calcium/calmodulin-dep ( 492) 620 62.8 2.1e-09
XP_016864165 (OMIM: 607708) PREDICTED: calcium/cal ( 494) 620 62.8 2.1e-09
XP_016864164 (OMIM: 607708) PREDICTED: calcium/cal ( 494) 620 62.8 2.1e-09
NP_001213 (OMIM: 602123) calcium/calmodulin-depend ( 495) 620 62.8 2.1e-09
NP_001212 (OMIM: 607708) calcium/calmodulin-depend ( 499) 620 62.8 2.1e-09
>>NP_000285 (OMIM: 172471,613027) phosphorylase b kinase (406 aa)
initn: 2754 init1: 2754 opt: 2754 Z-score: 1163.1 bits: 224.1 E(85289): 4.8e-58
Smith-Waterman score: 2754; 100.0% identity (100.0% similar) in 406 aa overlap (1-406:1-406)
10 20 30 40 50 60
pF1KE0 MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 RLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 EKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQIL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 MLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFERCEGSQPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFERCEGSQPW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 NLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNCAFRLYGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNCAFRLYGH
310 320 330 340 350 360
370 380 390 400
pF1KE0 WVKKGEQQNRAALFQHRPPGPFPIMGPEEEGDSAAITEDEAVLVLG
::::::::::::::::::::::::::::::::::::::::::::::
NP_000 WVKKGEQQNRAALFQHRPPGPFPIMGPEEEGDSAAITEDEAVLVLG
370 380 390 400
>>NP_001165903 (OMIM: 172471,613027) phosphorylase b kin (374 aa)
initn: 2463 init1: 2463 opt: 2463 Z-score: 1044.3 bits: 202.0 E(85289): 2e-51
Smith-Waterman score: 2463; 99.5% identity (100.0% similar) in 364 aa overlap (1-364:1-364)
10 20 30 40 50 60
pF1KE0 MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 RLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 EKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQIL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 MLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFERCEGSQPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFERCEGSQPW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 NLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNCAFRLYGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNCAFRLYGH
310 320 330 340 350 360
370 380 390 400
pF1KE0 WVKKGEQQNRAALFQHRPPGPFPIMGPEEEGDSAAITEDEAVLVLG
:..:
NP_001 WIRKQWIGKLMACV
370
>>NP_006204 (OMIM: 172470) phosphorylase b kinase gamma (387 aa)
initn: 1718 init1: 1509 opt: 1717 Z-score: 739.2 bits: 145.6 E(85289): 2e-34
Smith-Waterman score: 1717; 64.5% identity (89.0% similar) in 372 aa overlap (8-378:4-375)
10 20 30 40 50 60
pF1KE0 MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAE
.. ::: .:..::..:.::...:::::::::::.:. :..:.:::...::.
NP_006 MTRDEALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGG
10 20 30 40 50
70 80 90 100 110
pF1KE0 -RLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYL
.:::...:.:::: .:. :::.:.:::.:: : :.::...:.:::::::..:::::::
NP_006 GSFSPEEVRELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 TEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLE
::::.:::::::.:::.:::.. :: ::::::::::::::::::.:.:.::::::.::
NP_006 TEKVTLSEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 PGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQI
:::.:::.::::.::::::..:::.: :::::::::.:. :::..::::::::::::.:.
NP_006 PGERLREVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQM
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 LMLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFERCEGSQP
::::::: :.:::.:::::: :.:::::.::.: :.:. : :::.:: ::::.. .
NP_006 LMLRMIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFFQQYLVEEV
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 WNLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNCAFRLYG
...:: .:.: . ::::. :. . .::.:.:.. ..::::::: .:.::: :::.::
NP_006 RHFSPRGKFKVIALTVLASVRIYYQYRRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYG
300 310 320 330 340 350
360 370 380 390 400
pF1KE0 HWVKKGEQQNRAALFQHRPPGPFPIMGPEEEGDSAAITEDEAVLVLG
::::::.::::::::.. :
NP_006 HWVKKGQQQNRAALFENTPKAVLLSLAEEDY
360 370 380
>>NP_001245389 (OMIM: 172470) phosphorylase b kinase gam (378 aa)
initn: 1650 init1: 1375 opt: 1590 Z-score: 687.3 bits: 136.0 E(85289): 1.5e-31
Smith-Waterman score: 1645; 62.9% identity (86.8% similar) in 372 aa overlap (8-378:4-366)
10 20 30 40 50 60
pF1KE0 MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAE
.. ::: .:..::..:.::...:::::::::::.:. :..:.:::...::.
NP_001 MTRDEALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGG
10 20 30 40 50
70 80 90 100 110
pF1KE0 -RLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYL
.:::...:.:::: .:. :::. : :.::...:.:::::::..:::::::
NP_001 GSFSPEEVRELREATLKEVDILRK---------LKDTYETNTFFFLVFDLMKRGELFDYL
60 70 80 90 100
120 130 140 150 160 170
pF1KE0 TEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLE
::::.:::::::.:::.:::.. :: ::::::::::::::::::.:.:.::::::.::
NP_001 TEKVTLSEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLE
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE0 PGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQI
:::.:::.::::.::::::..:::.: :::::::::.:. :::..::::::::::::.:.
NP_001 PGERLREVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQM
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE0 LMLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFERCEGSQP
::::::: :.:::.:::::: :.:::::.::.: :.:. : :::.:: ::::.. .
NP_001 LMLRMIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFFQQYLVEEV
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE0 WNLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNCAFRLYG
...:: .:.: . ::::. :. . .::.:.:.. ..::::::: .:.::: :::.::
NP_001 RHFSPRGKFKVIALTVLASVRIYYQYRRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYG
290 300 310 320 330 340
360 370 380 390 400
pF1KE0 HWVKKGEQQNRAALFQHRPPGPFPIMGPEEEGDSAAITEDEAVLVLG
::::::.::::::::.. :
NP_001 HWVKKGQQQNRAALFENTPKAVLLSLAEEDY
350 360 370
>>NP_001245388 (OMIM: 172470) phosphorylase b kinase gam (419 aa)
initn: 1713 init1: 1317 opt: 1317 Z-score: 575.3 bits: 115.4 E(85289): 2.6e-25
Smith-Waterman score: 1643; 59.4% identity (81.9% similar) in 404 aa overlap (8-378:4-407)
10 20 30 40 50 60
pF1KE0 MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAE
.. ::: .:..::..:.::...:::::::::::.:. :..:.:::...::.
NP_001 MTRDEALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGG
10 20 30 40 50
70 80 90 100
pF1KE0 -RLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDL----------
.:::...:.:::: .:. :::.:.:::.:: : :.::...:.::::::
NP_001 GSFSPEEVRELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLWEDTDTMEME
60 70 80 90 100 110
110 120 130 140
pF1KE0 ----------------------MRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHAN
:..:::::::::::.:::::::.:::.:::.. ::
NP_001 QKWCLGWDSPKSTNFRAQGRARMKRGELFDYLTEKVTLSEKETRKIMRALLEVICTLHKL
120 130 140 150 160 170
150 160 170 180 190 200
pF1KE0 NIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETH
::::::::::::::::::.:.:.::::::.:::::.:::.::::.::::::..:::.: :
NP_001 NIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLREVCGTPSYLAPEIIECSMNEDH
180 190 200 210 220 230
210 220 230 240 250 260
pF1KE0 PGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSSTVKDL
::::::::.:. :::..::::::::::::.:.::::::: :.:::.:::::: :.:::::
NP_001 PGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDL
240 250 260 270 280 290
270 280 290 300 310 320
pF1KE0 ISRLLQVDPEARLTAEQALQHPFFERCEGSQPWNLTPRQRFRVAVWTVLAAGRVALSTHR
.::.: :.:. : :::.:: ::::.. . ...:: .:.: . ::::. :. . .:
NP_001 VSRFLVVQPQNRYTAEEALAHPFFQQYLVEEVRHFSPRGKFKVIALTVLASVRIYYQYRR
300 310 320 330 340 350
330 340 350 360 370 380
pF1KE0 VRPLTKNALLRDPYALRSVRHLIDNCAFRLYGHWVKKGEQQNRAALFQHRPPGPFPIMGP
:.:.:.. ..::::::: .:.::: :::.::::::::.::::::::.. :
NP_001 VKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFENTPKAVLLSLAE
360 370 380 390 400 410
390 400
pF1KE0 EEEGDSAAITEDEAVLVLG
NP_001 EDY
>>XP_005271829 (OMIM: 172470) PREDICTED: phosphorylase b (309 aa)
initn: 1379 init1: 1296 opt: 1310 Z-score: 573.5 bits: 114.6 E(85289): 3.3e-25
Smith-Waterman score: 1310; 67.0% identity (88.3% similar) in 273 aa overlap (106-378:25-297)
80 90 100 110 120 130
pF1KE0 RETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMR
.. :..:::::::::::.:::::::.:::
XP_005 MTRDEALPDSHSAQDFYENYEPKEILGRMKRGELFDYLTEKVTLSEKETRKIMR
10 20 30 40 50
140 150 160 170 180 190
pF1KE0 SLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLA
.:::.. :: ::::::::::::::::::.:.:.::::::.:::::.:::.::::.:::
XP_005 ALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLREVCGTPSYLA
60 70 80 90 100 110
200 210 220 230 240 250
pF1KE0 PEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSP
:::..:::.: :::::::::.:. :::..::::::::::::.:.::::::: :.:::.::
XP_005 PEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSP
120 130 140 150 160 170
260 270 280 290 300 310
pF1KE0 EWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFERCEGSQPWNLTPRQRFRVAVWTV
:::: :.:::::.::.: :.:. : :::.:: ::::.. . ...:: .:.: . ::
XP_005 EWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFFQQYLVEEVRHFSPRGKFKVIALTV
180 190 200 210 220 230
320 330 340 350 360 370
pF1KE0 LAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNCAFRLYGHWVKKGEQQNRAALFQ
::. :. . .::.:.:.. ..::::::: .:.::: :::.::::::::.::::::::.
XP_005 LASVRIYYQYRRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFE
240 250 260 270 280 290
380 390 400
pF1KE0 HRPPGPFPIMGPEEEGDSAAITEDEAVLVLG
. :
XP_005 NTPKAVLLSLAEEDY
300
>>XP_016867816 (OMIM: 172470) PREDICTED: phosphorylase b (326 aa)
initn: 1289 init1: 895 opt: 902 Z-score: 406.5 bits: 83.8 E(85289): 6.7e-16
Smith-Waterman score: 1209; 58.3% identity (76.1% similar) in 314 aa overlap (110-378:1-314)
80 90 100 110 120 130
pF1KE0 ILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLE
:..:::::::::::.:::::::.:::.:::
XP_016 MKRGELFDYLTEKVTLSEKETRKIMRALLE
10 20 30
140 150 160 170 180
pF1KE0 AVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLR--------------
.. :: ::::::::::::::::::.:.:.::::::.:::::.::
XP_016 VICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLRVETGFHHVGQAGLE
40 50 60 70 80 90
190 200 210
pF1KE0 -------------------------------ELCGTPGYLAPEILKCSMDETHPGYGKEV
:.::::.::::::..:::.: ::::::::
XP_016 LLTLRSARLGLPKCCDYRREPPCPAGLGISSEVCGTPSYLAPEIIECSMNEDHPGYGKEV
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE0 DLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQV
:.:. :::..::::::::::::.:.::::::: :.:::.:::::: :.:::::.::.: :
XP_016 DMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLVSRFLVV
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE0 DPEARLTAEQALQHPFFERCEGSQPWNLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKN
.:. : :::.:: ::::.. . ...:: .:.: . ::::. :. . .::.:.:..
XP_016 QPQNRYTAEEALAHPFFQQYLVEEVRHFSPRGKFKVIALTVLASVRIYYQYRRVKPVTRE
220 230 240 250 260 270
340 350 360 370 380 390
pF1KE0 ALLRDPYALRSVRHLIDNCAFRLYGHWVKKGEQQNRAALFQHRPPGPFPIMGPEEEGDSA
..::::::: .:.::: :::.::::::::.::::::::.. :
XP_016 IVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFENTPKAVLLSLAEEDY
280 290 300 310 320
400
pF1KE0 AITEDEAVLVLG
>>XP_016867815 (OMIM: 172470) PREDICTED: phosphorylase b (354 aa)
initn: 1290 init1: 895 opt: 902 Z-score: 406.2 bits: 83.9 E(85289): 6.9e-16
Smith-Waterman score: 1210; 57.5% identity (75.8% similar) in 318 aa overlap (106-378:25-342)
80 90 100 110 120 130
pF1KE0 RETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMR
.. :..:::::::::::.:::::::.:::
XP_016 MTRDEALPDSHSAQDFYENYEPKEILGRMKRGELFDYLTEKVTLSEKETRKIMR
10 20 30 40 50
140 150 160 170 180
pF1KE0 SLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLR----------
.:::.. :: ::::::::::::::::::.:.:.::::::.:::::.::
XP_016 ALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLRVETGFHHVGQ
60 70 80 90 100 110
190 200 210
pF1KE0 -----------------------------------ELCGTPGYLAPEILKCSMDETHPGY
:.::::.::::::..:::.: ::::
XP_016 AGLELLTLRSARLGLPKCCDYRREPPCPAGLGISSEVCGTPSYLAPEIIECSMNEDHPGY
120 130 140 150 160 170
220 230 240 250 260 270
pF1KE0 GKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSSTVKDLISR
:::::.:. :::..::::::::::::.:.::::::: :.:::.:::::: :.:::::.::
XP_016 GKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLVSR
180 190 200 210 220 230
280 290 300 310 320 330
pF1KE0 LLQVDPEARLTAEQALQHPFFERCEGSQPWNLTPRQRFRVAVWTVLAAGRVALSTHRVRP
.: :.:. : :::.:: ::::.. . ...:: .:.: . ::::. :. . .::.:
XP_016 FLVVQPQNRYTAEEALAHPFFQQYLVEEVRHFSPRGKFKVIALTVLASVRIYYQYRRVKP
240 250 260 270 280 290
340 350 360 370 380 390
pF1KE0 LTKNALLRDPYALRSVRHLIDNCAFRLYGHWVKKGEQQNRAALFQHRPPGPFPIMGPEEE
.:.. ..::::::: .:.::: :::.::::::::.::::::::.. :
XP_016 VTREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFENTPKAVLLSLAEEDY
300 310 320 330 340 350
400
pF1KE0 GDSAAITEDEAVLVLG
>>XP_016867814 (OMIM: 172470) PREDICTED: phosphorylase b (378 aa)
initn: 1289 init1: 895 opt: 902 Z-score: 406.0 bits: 83.9 E(85289): 7.1e-16
Smith-Waterman score: 1209; 58.3% identity (76.1% similar) in 314 aa overlap (110-378:53-366)
80 90 100 110 120 130
pF1KE0 ILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLE
:..:::::::::::.:::::::.:::.:::
XP_016 LQPGGGAGAARSHAEGGGHPAQGLRAPQHQMKRGELFDYLTEKVTLSEKETRKIMRALLE
30 40 50 60 70 80
140 150 160 170 180
pF1KE0 AVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLR--------------
.. :: ::::::::::::::::::.:.:.::::::.:::::.::
XP_016 VICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLRVETGFHHVGQAGLE
90 100 110 120 130 140
190 200 210
pF1KE0 -------------------------------ELCGTPGYLAPEILKCSMDETHPGYGKEV
:.::::.::::::..:::.: ::::::::
XP_016 LLTLRSARLGLPKCCDYRREPPCPAGLGISSEVCGTPSYLAPEIIECSMNEDHPGYGKEV
150 160 170 180 190 200
220 230 240 250 260 270
pF1KE0 DLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQV
:.:. :::..::::::::::::.:.::::::: :.:::.:::::: :.:::::.::.: :
XP_016 DMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLVSRFLVV
210 220 230 240 250 260
280 290 300 310 320 330
pF1KE0 DPEARLTAEQALQHPFFERCEGSQPWNLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKN
.:. : :::.:: ::::.. . ...:: .:.: . ::::. :. . .::.:.:..
XP_016 QPQNRYTAEEALAHPFFQQYLVEEVRHFSPRGKFKVIALTVLASVRIYYQYRRVKPVTRE
270 280 290 300 310 320
340 350 360 370 380 390
pF1KE0 ALLRDPYALRSVRHLIDNCAFRLYGHWVKKGEQQNRAALFQHRPPGPFPIMGPEEEGDSA
..::::::: .:.::: :::.::::::::.::::::::.. :
XP_016 IVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFENTPKAVLLSLAEEDY
330 340 350 360 370
400
pF1KE0 AITEDEAVLVLG
>>XP_016867813 (OMIM: 172470) PREDICTED: phosphorylase b (432 aa)
initn: 1699 init1: 895 opt: 902 Z-score: 405.5 bits: 84.0 E(85289): 7.5e-16
Smith-Waterman score: 1597; 57.9% identity (79.7% similar) in 409 aa overlap (16-378:12-420)
10 20 30 40 50 60
pF1KE0 MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAE
.:..::..:.::...:::::::::::.:. :..:.:::...::.
XP_016 MTRDEALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGG
10 20 30 40 50
70 80 90 100 110
pF1KE0 -RLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYL
.:::...:.:::: .:. :::.:.:::.:: : :.::...:.:::::::..:::::::
XP_016 GSFSPEEVRELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 TEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLE
::::.:::::::.:::.:::.. :: ::::::::::::::::::.:.:.::::::.::
XP_016 TEKVTLSEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLE
120 130 140 150 160 170
180 190
pF1KE0 PGEKLR---------------------------------------------ELCGTPGYL
:::.:: :.::::.::
XP_016 PGERLRVETGFHHVGQAGLELLTLRSARLGLPKCCDYRREPPCPAGLGISSEVCGTPSYL
180 190 200 210 220 230
200 210 220 230 240 250
pF1KE0 APEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSS
::::..:::.: :::::::::.:. :::..::::::::::::.:.::::::: :.:::.:
XP_016 APEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGS
240 250 260 270 280 290
260 270 280 290 300 310
pF1KE0 PEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFERCEGSQPWNLTPRQRFRVAVWT
::::: :.:::::.::.: :.:. : :::.:: ::::.. . ...:: .:.: . :
XP_016 PEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFFQQYLVEEVRHFSPRGKFKVIALT
300 310 320 330 340 350
320 330 340 350 360 370
pF1KE0 VLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNCAFRLYGHWVKKGEQQNRAALF
:::. :. . .::.:.:.. ..::::::: .:.::: :::.::::::::.::::::::
XP_016 VLASVRIYYQYRRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALF
360 370 380 390 400 410
380 390 400
pF1KE0 QHRPPGPFPIMGPEEEGDSAAITEDEAVLVLG
.. :
XP_016 ENTPKAVLLSLAEEDY
420 430
406 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 02:51:19 2016 done: Sat Nov 5 02:51:20 2016
Total Scan time: 8.070 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]