Result of FASTA (omim) for
pF1KE0692
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0692, 402 aa
1>>>pF1KE0692 402 - 402 aa - 402 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.8220+/-0.000362; mu= 6.5932+/- 0.022
mean_var=248.5890+/-58.925, 0's: 0 Z-trim(121.2): 134 B-trim: 3567 in 2/57
Lambda= 0.081345
statistics sampled from 37044 (37382) to 37044 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.772), E-opt: 0.2 (0.438), width: 16
Scan time: 10.130
The best scores are: opt bits E(85289)
NP_003140 (OMIM: 602317) SH3 and cysteine-rich dom ( 402) 2737 334.3 3.3e-91
XP_011532338 (OMIM: 602317) PREDICTED: SH3 and cys ( 406) 2491 305.4 1.6e-82
XP_011532339 (OMIM: 602317) PREDICTED: SH3 and cys ( 391) 2436 298.9 1.4e-80
XP_011532340 (OMIM: 602317) PREDICTED: SH3 and cys ( 334) 2298 282.6 9.5e-76
XP_016862572 (OMIM: 602317) PREDICTED: SH3 and cys ( 334) 2298 282.6 9.5e-76
XP_016862573 (OMIM: 602317) PREDICTED: SH3 and cys ( 215) 1456 183.6 4e-46
NP_001278978 (OMIM: 602317) SH3 and cysteine-rich ( 341) 1451 183.2 8e-46
NP_001273186 (OMIM: 255995,615521) SH3 and cystein ( 178) 431 63.2 5.8e-10
NP_001273185 (OMIM: 255995,615521) SH3 and cystein ( 325) 431 63.5 8.4e-10
NP_659501 (OMIM: 255995,615521) SH3 and cysteine-r ( 364) 431 63.6 9.1e-10
XP_011536428 (OMIM: 255995,615521) PREDICTED: SH3 ( 364) 431 63.6 9.1e-10
>>NP_003140 (OMIM: 602317) SH3 and cysteine-rich domain- (402 aa)
initn: 2737 init1: 2737 opt: 2737 Z-score: 1758.4 bits: 334.3 E(85289): 3.3e-91
Smith-Waterman score: 2737; 99.8% identity (100.0% similar) in 402 aa overlap (1-402:1-402)
10 20 30 40 50 60
pF1KE0 MIPPSSPREDGVDGLPKEAVGAEQPPSPASTSSQESKLQKLKRSLSFKTKSLRSKSADNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MIPPSSPREDGVDGLPKEAVGAEQPPSPASTSSQESKLQKLKRSLSFKTKSLRSKSADNF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 FQRTNSEDMKLQAHMVAEISPSSSPLPAPGSLTSTPARAGLHPGGKAHAFHEYIFKKPTF
::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
NP_003 FQRTNSEDMKLQAHMVAEISPSSSPLPAPGSLTSTPARAGLHPGGKAHAFQEYIFKKPTF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 CDVCNHMIVGTNAKHGLRCKACKMSIHHKCTDGLAPQRCMGKLPKGFRRYYSSPLLIHEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 CDVCNHMIVGTNAKHGLRCKACKMSIHHKCTDGLAPQRCMGKLPKGFRRYYSSPLLIHEQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 FGCIKEVMPIACGNKVDPVYETLRFGTSLAQRTKKGSSGSGSDSPHRTSTSDLVEVPEEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FGCIKEVMPIACGNKVDPVYETLRFGTSLAQRTKKGSSGSGSDSPHRTSTSDLVEVPEEA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 NGPGGGYDLRKRSNSVFTYPENGTDDFRDPAKNINHQGSLSKDPLQMNTYVALYKFVPQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NGPGGGYDLRKRSNSVFTYPENGTDDFRDPAKNINHQGSLSKDPLQMNTYVALYKFVPQE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 NEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANFVQRLQQNEKIFRCVRTFIGCKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANFVQRLQQNEKIFRCVRTFIGCKE
310 320 330 340 350 360
370 380 390 400
pF1KE0 QGQITLKENQICVSSEEEQDGFIRVLSGKKKGLIPLDVLENI
::::::::::::::::::::::::::::::::::::::::::
NP_003 QGQITLKENQICVSSEEEQDGFIRVLSGKKKGLIPLDVLENI
370 380 390 400
>>XP_011532338 (OMIM: 602317) PREDICTED: SH3 and cystein (406 aa)
initn: 2490 init1: 2490 opt: 2491 Z-score: 1602.4 bits: 305.4 E(85289): 1.6e-82
Smith-Waterman score: 2491; 94.8% identity (97.2% similar) in 388 aa overlap (16-402:19-406)
10 20 30 40 50
pF1KE0 MIPPSSPREDGVDGLPKEAVGAEQPPSPA-STSSQESKLQKLKRSLSFKTKSLRSKS
:. . : . : : . ... .:::::::::::::::::::
XP_011 MILHSDTDLKISCIHSIHPRASWGKIEEASHALNYQGNIFQLQKLKRSLSFKTKSLRSKS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 ADNFFQRTNSEDMKLQAHMVAEISPSSSPLPAPGSLTSTPARAGLHPGGKAHAFHEYIFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::
XP_011 ADNFFQRTNSEDMKLQAHMVAEISPSSSPLPAPGSLTSTPARAGLHPGGKAHAFQEYIFK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 KPTFCDVCNHMIVGTNAKHGLRCKACKMSIHHKCTDGLAPQRCMGKLPKGFRRYYSSPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPTFCDVCNHMIVGTNAKHGLRCKACKMSIHHKCTDGLAPQRCMGKLPKGFRRYYSSPLL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 IHEQFGCIKEVMPIACGNKVDPVYETLRFGTSLAQRTKKGSSGSGSDSPHRTSTSDLVEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHEQFGCIKEVMPIACGNKVDPVYETLRFGTSLAQRTKKGSSGSGSDSPHRTSTSDLVEV
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE0 PEEANGPGGGYDLRKRSNSVFTYPENGTDDFRDPAKNINHQGSLSKDPLQMNTYVALYKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEEANGPGGGYDLRKRSNSVFTYPENGTDDFRDPAKNINHQGSLSKDPLQMNTYVALYKF
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE0 VPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANFVQRLQQNEKIFRCVRTFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANFVQRLQQNEKIFRCVRTFI
310 320 330 340 350 360
360 370 380 390 400
pF1KE0 GCKEQGQITLKENQICVSSEEEQDGFIRVLSGKKKGLIPLDVLENI
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCKEQGQITLKENQICVSSEEEQDGFIRVLSGKKKGLIPLDVLENI
370 380 390 400
>>XP_011532339 (OMIM: 602317) PREDICTED: SH3 and cystein (391 aa)
initn: 2429 init1: 2429 opt: 2436 Z-score: 1567.7 bits: 298.9 E(85289): 1.4e-80
Smith-Waterman score: 2640; 97.0% identity (97.3% similar) in 402 aa overlap (1-402:1-391)
10 20 30 40 50 60
pF1KE0 MIPPSSPREDGVDGLPKEAVGAEQPPSPASTSSQESKLQKLKRSLSFKTKSLRSKSADNF
::::::::::::::::::::::::::::::::::::: ::::::::::::
XP_011 MIPPSSPREDGVDGLPKEAVGAEQPPSPASTSSQESK-----------TKSLRSKSADNF
10 20 30 40
70 80 90 100 110 120
pF1KE0 FQRTNSEDMKLQAHMVAEISPSSSPLPAPGSLTSTPARAGLHPGGKAHAFHEYIFKKPTF
::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
XP_011 FQRTNSEDMKLQAHMVAEISPSSSPLPAPGSLTSTPARAGLHPGGKAHAFQEYIFKKPTF
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE0 CDVCNHMIVGTNAKHGLRCKACKMSIHHKCTDGLAPQRCMGKLPKGFRRYYSSPLLIHEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CDVCNHMIVGTNAKHGLRCKACKMSIHHKCTDGLAPQRCMGKLPKGFRRYYSSPLLIHEQ
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE0 FGCIKEVMPIACGNKVDPVYETLRFGTSLAQRTKKGSSGSGSDSPHRTSTSDLVEVPEEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGCIKEVMPIACGNKVDPVYETLRFGTSLAQRTKKGSSGSGSDSPHRTSTSDLVEVPEEA
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE0 NGPGGGYDLRKRSNSVFTYPENGTDDFRDPAKNINHQGSLSKDPLQMNTYVALYKFVPQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGPGGGYDLRKRSNSVFTYPENGTDDFRDPAKNINHQGSLSKDPLQMNTYVALYKFVPQE
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE0 NEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANFVQRLQQNEKIFRCVRTFIGCKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANFVQRLQQNEKIFRCVRTFIGCKE
290 300 310 320 330 340
370 380 390 400
pF1KE0 QGQITLKENQICVSSEEEQDGFIRVLSGKKKGLIPLDVLENI
::::::::::::::::::::::::::::::::::::::::::
XP_011 QGQITLKENQICVSSEEEQDGFIRVLSGKKKGLIPLDVLENI
350 360 370 380 390
>>XP_011532340 (OMIM: 602317) PREDICTED: SH3 and cystein (334 aa)
initn: 2298 init1: 2298 opt: 2298 Z-score: 1480.9 bits: 282.6 E(85289): 9.5e-76
Smith-Waterman score: 2298; 99.7% identity (100.0% similar) in 334 aa overlap (69-402:1-334)
40 50 60 70 80 90
pF1KE0 QKLKRSLSFKTKSLRSKSADNFFQRTNSEDMKLQAHMVAEISPSSSPLPAPGSLTSTPAR
::::::::::::::::::::::::::::::
XP_011 MKLQAHMVAEISPSSSPLPAPGSLTSTPAR
10 20 30
100 110 120 130 140 150
pF1KE0 AGLHPGGKAHAFHEYIFKKPTFCDVCNHMIVGTNAKHGLRCKACKMSIHHKCTDGLAPQR
::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGLHPGGKAHAFQEYIFKKPTFCDVCNHMIVGTNAKHGLRCKACKMSIHHKCTDGLAPQR
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE0 CMGKLPKGFRRYYSSPLLIHEQFGCIKEVMPIACGNKVDPVYETLRFGTSLAQRTKKGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CMGKLPKGFRRYYSSPLLIHEQFGCIKEVMPIACGNKVDPVYETLRFGTSLAQRTKKGSS
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE0 GSGSDSPHRTSTSDLVEVPEEANGPGGGYDLRKRSNSVFTYPENGTDDFRDPAKNINHQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSGSDSPHRTSTSDLVEVPEEANGPGGGYDLRKRSNSVFTYPENGTDDFRDPAKNINHQG
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE0 SLSKDPLQMNTYVALYKFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLSKDPLQMNTYVALYKFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANF
220 230 240 250 260 270
340 350 360 370 380 390
pF1KE0 VQRLQQNEKIFRCVRTFIGCKEQGQITLKENQICVSSEEEQDGFIRVLSGKKKGLIPLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQRLQQNEKIFRCVRTFIGCKEQGQITLKENQICVSSEEEQDGFIRVLSGKKKGLIPLDV
280 290 300 310 320 330
400
pF1KE0 LENI
::::
XP_011 LENI
>>XP_016862572 (OMIM: 602317) PREDICTED: SH3 and cystein (334 aa)
initn: 2298 init1: 2298 opt: 2298 Z-score: 1480.9 bits: 282.6 E(85289): 9.5e-76
Smith-Waterman score: 2298; 99.7% identity (100.0% similar) in 334 aa overlap (69-402:1-334)
40 50 60 70 80 90
pF1KE0 QKLKRSLSFKTKSLRSKSADNFFQRTNSEDMKLQAHMVAEISPSSSPLPAPGSLTSTPAR
::::::::::::::::::::::::::::::
XP_016 MKLQAHMVAEISPSSSPLPAPGSLTSTPAR
10 20 30
100 110 120 130 140 150
pF1KE0 AGLHPGGKAHAFHEYIFKKPTFCDVCNHMIVGTNAKHGLRCKACKMSIHHKCTDGLAPQR
::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGLHPGGKAHAFQEYIFKKPTFCDVCNHMIVGTNAKHGLRCKACKMSIHHKCTDGLAPQR
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE0 CMGKLPKGFRRYYSSPLLIHEQFGCIKEVMPIACGNKVDPVYETLRFGTSLAQRTKKGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CMGKLPKGFRRYYSSPLLIHEQFGCIKEVMPIACGNKVDPVYETLRFGTSLAQRTKKGSS
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE0 GSGSDSPHRTSTSDLVEVPEEANGPGGGYDLRKRSNSVFTYPENGTDDFRDPAKNINHQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGSDSPHRTSTSDLVEVPEEANGPGGGYDLRKRSNSVFTYPENGTDDFRDPAKNINHQG
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE0 SLSKDPLQMNTYVALYKFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLSKDPLQMNTYVALYKFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANF
220 230 240 250 260 270
340 350 360 370 380 390
pF1KE0 VQRLQQNEKIFRCVRTFIGCKEQGQITLKENQICVSSEEEQDGFIRVLSGKKKGLIPLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQRLQQNEKIFRCVRTFIGCKEQGQITLKENQICVSSEEEQDGFIRVLSGKKKGLIPLDV
280 290 300 310 320 330
400
pF1KE0 LENI
::::
XP_016 LENI
>>XP_016862573 (OMIM: 602317) PREDICTED: SH3 and cystein (215 aa)
initn: 1456 init1: 1456 opt: 1456 Z-score: 949.1 bits: 183.6 E(85289): 4e-46
Smith-Waterman score: 1456; 100.0% identity (100.0% similar) in 215 aa overlap (188-402:1-215)
160 170 180 190 200 210
pF1KE0 RCMGKLPKGFRRYYSSPLLIHEQFGCIKEVMPIACGNKVDPVYETLRFGTSLAQRTKKGS
::::::::::::::::::::::::::::::
XP_016 MPIACGNKVDPVYETLRFGTSLAQRTKKGS
10 20 30
220 230 240 250 260 270
pF1KE0 SGSGSDSPHRTSTSDLVEVPEEANGPGGGYDLRKRSNSVFTYPENGTDDFRDPAKNINHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGSGSDSPHRTSTSDLVEVPEEANGPGGGYDLRKRSNSVFTYPENGTDDFRDPAKNINHQ
40 50 60 70 80 90
280 290 300 310 320 330
pF1KE0 GSLSKDPLQMNTYVALYKFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSLSKDPLQMNTYVALYKFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPAN
100 110 120 130 140 150
340 350 360 370 380 390
pF1KE0 FVQRLQQNEKIFRCVRTFIGCKEQGQITLKENQICVSSEEEQDGFIRVLSGKKKGLIPLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVQRLQQNEKIFRCVRTFIGCKEQGQITLKENQICVSSEEEQDGFIRVLSGKKKGLIPLD
160 170 180 190 200 210
400
pF1KE0 VLENI
:::::
XP_016 VLENI
>>NP_001278978 (OMIM: 602317) SH3 and cysteine-rich doma (341 aa)
initn: 1442 init1: 1442 opt: 1451 Z-score: 943.6 bits: 183.2 E(85289): 8e-46
Smith-Waterman score: 2158; 84.6% identity (84.8% similar) in 402 aa overlap (1-402:1-341)
10 20 30 40 50 60
pF1KE0 MIPPSSPREDGVDGLPKEAVGAEQPPSPASTSSQESKLQKLKRSLSFKTKSLRSKSADNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIPPSSPREDGVDGLPKEAVGAEQPPSPASTSSQESKLQKLKRSLSFKTKSLRSKSADNF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 FQRTNSEDMKLQAHMVAEISPSSSPLPAPGSLTSTPARAGLHPGGKAHAFHEYIFKKPTF
::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
NP_001 FQRTNSEDMKLQAHMVAEISPSSSPLPAPGSLTSTPARAGLHPGGKAHAFQEYIFKKPTF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 CDVCNHMIVGTNAKHGLRCKACKMSIHHKCTDGLAPQRCMGKLPKGFRRYYSSPLLIHEQ
:::::::::
NP_001 CDVCNHMIV---------------------------------------------------
190 200 210 220 230 240
pF1KE0 FGCIKEVMPIACGNKVDPVYETLRFGTSLAQRTKKGSSGSGSDSPHRTSTSDLVEVPEEA
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ----------ACGNKVDPVYETLRFGTSLAQRTKKGSSGSGSDSPHRTSTSDLVEVPEEA
130 140 150 160 170
250 260 270 280 290 300
pF1KE0 NGPGGGYDLRKRSNSVFTYPENGTDDFRDPAKNINHQGSLSKDPLQMNTYVALYKFVPQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGPGGGYDLRKRSNSVFTYPENGTDDFRDPAKNINHQGSLSKDPLQMNTYVALYKFVPQE
180 190 200 210 220 230
310 320 330 340 350 360
pF1KE0 NEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANFVQRLQQNEKIFRCVRTFIGCKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANFVQRLQQNEKIFRCVRTFIGCKE
240 250 260 270 280 290
370 380 390 400
pF1KE0 QGQITLKENQICVSSEEEQDGFIRVLSGKKKGLIPLDVLENI
::::::::::::::::::::::::::::::::::::::::::
NP_001 QGQITLKENQICVSSEEEQDGFIRVLSGKKKGLIPLDVLENI
300 310 320 330 340
>>NP_001273186 (OMIM: 255995,615521) SH3 and cysteine-ri (178 aa)
initn: 417 init1: 417 opt: 431 Z-score: 299.9 bits: 63.2 E(85289): 5.8e-10
Smith-Waterman score: 431; 41.7% identity (76.4% similar) in 144 aa overlap (260-402:35-178)
230 240 250 260 270 280
pF1KE0 TSDLVEVPEEANGPGGGYDLRKRSNSVFTYPENGTDDFRDPAKNINHQGSLSKDPLQMNT
:..:. . :.. . . . .. .:..
NP_001 ERKKGQADKKNPVAAMMEEEPESARPEEGKPQDGNPEGDKKAEKKTPDDKHKQPGFQQSH
10 20 30 40 50 60
290 300 310 320 330 340
pF1KE0 Y-VALYKFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANFVQRLQQNEKI
: ::::.: :..::.. ::. ::...::::.::.::: ...:::: ::. :.. .:..
NP_001 YFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERV
70 80 90 100 110 120
350 360 370 380 390 400
pF1KE0 FRCVRTFIGCKEQGQITLKENQICVSSEEEQDGFIRVLSGKKKGLIPLDVLENI
: .:.:.: .: ::::::..:: :.. .: :...: .:.: ::.: : ::.:
NP_001 HRVTRSFVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDFLEEI
130 140 150 160 170
>>NP_001273185 (OMIM: 255995,615521) SH3 and cysteine-ri (325 aa)
initn: 692 init1: 417 opt: 431 Z-score: 296.9 bits: 63.5 E(85289): 8.4e-10
Smith-Waterman score: 797; 40.9% identity (69.8% similar) in 298 aa overlap (106-402:49-325)
80 90 100 110 120 130
pF1KE0 VAEISPSSSPLPAPGSLTSTPARAGLHPGGKAHAFHEYIFKKPTFCDVCNHMIVGTNAKH
: : :....:::: ::::: .::: : :
NP_001 GPIYYIYEEEEEEEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIV-LNNKF
20 30 40 50 60 70
140 150 160 170 180 190
pF1KE0 GLRCKACKMSIHHKCTDGLAPQRCMGKLPKGFRRYYSSPLLIHEQFGCIKEVMPIACGNK
::::: :: .::..: . . :::.::.: ::.: ::::: ..:..:.:. .. .:.
NP_001 GLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQYACVKD---LSAANR
80 90 100 110 120 130
200 210 220 230 240 250
pF1KE0 VDPVYETLRFGTSLAQRTKKGSSGSGSDSPHRTSTSDLVEVPEEANGPGGGYDLRKRSNS
:::.:::: :. .:.. .: .:. . . .. . : :: : : :
NP_001 NDPVFETLRTGVIMANKERK----KGQADKKNPVAAMMEEEPESAR-PEEGK--------
140 150 160 170 180
260 270 280 290 300 310
pF1KE0 VFTYPENGTDDFRDPAKNINHQGSLSKDPLQMNTY-VALYKFVPQENEDLEMRPGDIITL
:..:. . :.. . . . .. .:.. : ::::.: :..::.. ::. ::.
NP_001 ----PQDGNPEGDKKAEKKTPDDKHKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITV
190 200 210 220 230
320 330 340 350 360 370
pF1KE0 LEDSNEDWWKGKIQDRIGFFPANFVQRLQQNEKIFRCVRTFIGCKEQGQITLKENQICVS
..::::.::.::: ...:::: ::. :.. .:.. : .:.:.: .: ::::::..:: :.
NP_001 IDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQ
240 250 260 270 280 290
380 390 400
pF1KE0 SEEEQDGFIRVLSGKKKGLIPLDVLENI
. .: :...: .:.: ::.: : ::.:
NP_001 KGDEAGGYVKVYTGRKVGLFPTDFLEEI
300 310 320
>>NP_659501 (OMIM: 255995,615521) SH3 and cysteine-rich (364 aa)
initn: 692 init1: 417 opt: 431 Z-score: 296.4 bits: 63.6 E(85289): 9.1e-10
Smith-Waterman score: 807; 36.0% identity (63.2% similar) in 394 aa overlap (17-402:4-364)
10 20 30 40 50
pF1KE0 MIPPSSPREDGVDGLPKEAVGAEQPPSPASTSSQESKLQKLKRSL---SFKTKSLR----
::.. . .: :: : ..: ::.::. : : :: ..
NP_659 MTEKEVLESPKPSFPAET--RQSGLQRLKQLLRKGSTGTKEMELPPE
10 20 30 40
60 70 80 90 100 110
pF1KE0 SKSADNFFQRTNSEDMKLQAHMVAEISPSSSPLPAPGSLTSTPARAGLHPGGKAHAFHEY
.. . .. . . . : : : : .:.. : : :...
NP_659 PQANGEAVGAGGGPIYYIYEEEEEEEEEEEEPPPEPPKLVND----------KPHKFKDH
50 60 70 80 90
120 130 140 150 160 170
pF1KE0 IFKKPTFCDVCNHMIVGTNAKHGLRCKACKMSIHHKCTDGLAPQRCMGKLPKGFRRYYSS
.:::: ::::: .::: : : ::::: :: .::..: . . :::.::.: ::.: :::
NP_659 FFKKPKFCDVCARMIV-LNNKFGLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSS
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE0 PLLIHEQFGCIKEVMPIACGNKVDPVYETLRFGTSLAQRTKKGSSGSGSDSPHRTSTSDL
:: ..:..:.:. .. .:. :::.:::: :. .:.. .: .:. . . .. .
NP_659 PLYSNQQYACVKD---LSAANRNDPVFETLRTGVIMANKERK----KGQADKKNPVAAMM
160 170 180 190 200
240 250 260 270 280 290
pF1KE0 VEVPEEANGPGGGYDLRKRSNSVFTYPENGTDDFRDPAKNINHQGSLSKDPLQMNTY-VA
: :: : : : :..:. . :.. . . . .. .:.. : ::
NP_659 EEEPESAR-PEEGK------------PQDGNPEGDKKAEKKTPDDKHKQPGFQQSHYFVA
210 220 230 240 250
300 310 320 330 340 350
pF1KE0 LYKFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANFVQRLQQNEKIFRCV
::.: :..::.. ::. ::...::::.::.::: ...:::: ::. :.. .:.. : .
NP_659 LYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVT
260 270 280 290 300 310
360 370 380 390 400
pF1KE0 RTFIGCKEQGQITLKENQICVSSEEEQDGFIRVLSGKKKGLIPLDVLENI
:.:.: .: ::::::..:: :.. .: :...: .:.: ::.: : ::.:
NP_659 RSFVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDFLEEI
320 330 340 350 360
402 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 08:03:26 2016 done: Sat Nov 5 08:03:28 2016
Total Scan time: 10.130 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]