Result of FASTA (omim) for
pF1KE0661
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0661, 236 aa
1>>>pF1KE0661 236 - 236 aa - 236 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6948+/-0.000507; mu= 11.4998+/- 0.032
mean_var=289.1153+/-70.360, 0's: 0 Z-trim(116.0): 160 B-trim: 3130 in 2/56
Lambda= 0.075429
statistics sampled from 26584 (26774) to 26584 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.657), E-opt: 0.2 (0.314), width: 16
Scan time: 3.780
The best scores are: opt bits E(85289)
NP_059965 (OMIM: 612428) RNA-binding protein 38 is ( 239) 871 107.8 1.7e-23
NP_906270 (OMIM: 612428) RNA-binding protein 38 is ( 121) 599 77.7 9.6e-15
NP_001278709 (OMIM: 612428) RNA-binding protein 38 ( 271) 538 71.7 1.4e-12
XP_011527187 (OMIM: 612428) PREDICTED: RNA-binding ( 247) 366 52.9 5.9e-07
XP_005260503 (OMIM: 612428) PREDICTED: RNA-binding ( 153) 342 49.9 2.8e-06
XP_011522588 (OMIM: 607897) PREDICTED: RNA-binding ( 242) 255 40.8 0.0025
XP_016879638 (OMIM: 607897) PREDICTED: RNA-binding ( 259) 255 40.9 0.0026
NP_001309179 (OMIM: 607897) RNA-binding protein Mu ( 324) 255 41.0 0.0029
XP_005257071 (OMIM: 607897) PREDICTED: RNA-binding ( 346) 255 41.1 0.003
XP_005257072 (OMIM: 607897) PREDICTED: RNA-binding ( 346) 255 41.1 0.003
XP_011536664 (OMIM: 603328) PREDICTED: RNA-binding ( 343) 252 40.7 0.0038
XP_016879636 (OMIM: 607897) PREDICTED: RNA-binding ( 315) 248 40.2 0.0049
>>NP_059965 (OMIM: 612428) RNA-binding protein 38 isofor (239 aa)
initn: 950 init1: 790 opt: 871 Z-score: 543.0 bits: 107.8 E(85289): 1.7e-23
Smith-Waterman score: 984; 68.1% identity (79.4% similar) in 238 aa overlap (1-236:24-239)
10 20 30
pF1KE0 MHTTQKDTTYTKIFVGGLPYHTTDASLRKYFEVFGEI
:: .:::::.:::::::::::::::::::::: ::.:
NP_059 MLLQPAPCAPSAGFPRPLAAPGAMHGSQKDTTFTKIFVGGLPYHTTDASLRKYFEGFGDI
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE0 EEAVVITDRQTGKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPRIMQP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: .:
NP_059 EEAVVITDRQTGKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPRSLQT
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE0 GFAFGVQQLHPALIQRPFGIPAHYVYPQAFVQPGVVIPHVQPTAAAASTTPYIDYTGA--
:::.:::::::.:::: .:. ::.:: :.:::.:::: . :. . .: :::.:: :
NP_059 GFAIGVQQLHPTLIQRTYGLTPHYIYPPAIVQPSVVIP-AAPVPSLSS--PYIEYTPASP
130 140 150 160 170
160 170 180 190 200 210
pF1KE0 AYAQYSAAAAAAAAAAAYDQYPYAASPAAAGYVTAGGYGYAVQQPITAAAPGTAAAAAAA
::::: :. :::::::::::.:. .. .: :: : ..::::
NP_059 AYAQYPPAT--------YDQYPYAASPATAASFVGYSYPAAVPQALSAAAP---------
180 190 200 210 220
220 230
pF1KE0 AAAAAAFGQYQPQQLQTDRMQ
:...: ::: ::: ::::
NP_059 --AGTTFVQYQAPQLQPDRMQ
230
>>NP_906270 (OMIM: 612428) RNA-binding protein 38 isofor (121 aa)
initn: 599 init1: 599 opt: 599 Z-score: 385.7 bits: 77.7 E(85289): 9.6e-15
Smith-Waterman score: 599; 91.8% identity (95.9% similar) in 98 aa overlap (1-98:24-121)
10 20 30
pF1KE0 MHTTQKDTTYTKIFVGGLPYHTTDASLRKYFEVFGEI
:: .:::::.:::::::::::::::::::::: ::.:
NP_906 MLLQPAPCAPSAGFPRPLAAPGAMHGSQKDTTFTKIFVGGLPYHTTDASLRKYFEGFGDI
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE0 EEAVVITDRQTGKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPRIMQP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: .:
NP_906 EEAVVITDRQTGKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPRSLQT
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE0 GFAFGVQQLHPALIQRPFGIPAHYVYPQAFVQPGVVIPHVQPTAAAASTTPYIDYTGAAY
:
NP_906 G
>>NP_001278709 (OMIM: 612428) RNA-binding protein 38 iso (271 aa)
initn: 936 init1: 451 opt: 538 Z-score: 346.6 bits: 71.7 E(85289): 1.4e-12
Smith-Waterman score: 910; 60.0% identity (70.0% similar) in 270 aa overlap (1-236:24-271)
10 20 30
pF1KE0 MHTTQKDTTYTKIFVGGLPYHTTDASLRKYFEVFGEI
:: .:::::.:::::::::::::::::::::: ::.:
NP_001 MLLQPAPCAPSAGFPRPLAAPGAMHGSQKDTTFTKIFVGGLPYHTTDASLRKYFEGFGDI
10 20 30 40 50 60
40 50 60
pF1KE0 EEAVVITDRQTGKSRGYGF--------------------------------VTMADRAAA
::::::::::::::::::: :::::::::
NP_001 EEAVVITDRQTGKSRGYGFGIIFVLEGHISQALNFDGRSWNPGGIFVGEPQVTMADRAAA
70 80 90 100 110 120
70 80 90 100 110 120
pF1KE0 ERACKDPNPIIDGRKANVNLAYLGAKPRIMQPGFAFGVQQLHPALIQRPFGIPAHYVYPQ
:::::::::::::::::::::::::::: .: :::.:::::::.:::: .:. ::.::
NP_001 ERACKDPNPIIDGRKANVNLAYLGAKPRSLQTGFAIGVQQLHPTLIQRTYGLTPHYIYPP
130 140 150 160 170 180
130 140 150 160 170 180
pF1KE0 AFVQPGVVIPHVQPTAAAASTTPYIDYTGA--AYAQYSAAAAAAAAAAAYDQYPYAASPA
:.:::.:::: . :. . .: :::.:: : ::::: :. :::::::::::
NP_001 AIVQPSVVIP-AAPVPSLSS--PYIEYTPASPAYAQYPPAT--------YDQYPYAASPA
190 200 210 220
190 200 210 220 230
pF1KE0 AAGYVTAGGYGYAVQQPITAAAPGTAAAAAAAAAAAAAFGQYQPQQLQTDRMQ
.:. .. .: :: : ..:::: :...: ::: ::: ::::
NP_001 TAASFVGYSYPAAVPQALSAAAP-----------AGTTFVQYQAPQLQPDRMQ
230 240 250 260 270
>>XP_011527187 (OMIM: 612428) PREDICTED: RNA-binding pro (247 aa)
initn: 685 init1: 360 opt: 366 Z-score: 245.8 bits: 52.9 E(85289): 5.9e-07
Smith-Waterman score: 625; 70.3% identity (75.0% similar) in 148 aa overlap (1-116:24-171)
10 20 30
pF1KE0 MHTTQKDTTYTKIFVGGLPYHTTDASLRKYFEVFGEI
:: .:::::.:::::::::::::::::::::: ::.:
XP_011 MLLQPAPCAPSAGFPRPLAAPGAMHGSQKDTTFTKIFVGGLPYHTTDASLRKYFEGFGDI
10 20 30 40 50 60
40 50 60
pF1KE0 EEAVVITDRQTGKSRGYGF--------------------------------VTMADRAAA
::::::::::::::::::: :::::::::
XP_011 EEAVVITDRQTGKSRGYGFGIIFVLEGHISQALNFDGRSWNPGGIFVGEPQVTMADRAAA
70 80 90 100 110 120
70 80 90 100 110 120
pF1KE0 ERACKDPNPIIDGRKANVNLAYLGAKPRIMQPGFAFGVQQLHPALIQRPFGIPAHYVYPQ
:::::::::::::::::::::::::::: .: :::.:::::::.:::: .:
XP_011 ERACKDPNPIIDGRKANVNLAYLGAKPRSLQTGFAIGVQQLHPTLIQRTYGRKMEVFTEA
130 140 150 160 170 180
130 140 150 160 170 180
pF1KE0 AFVQPGVVIPHVQPTAAAASTTPYIDYTGAAYAQYSAAAAAAAAAAAYDQYPYAASPAAA
XP_011 TTGFHLSLTGHNWVTGHGHHRGSEMRRQAPRTPECQADPALHLPTSHRAAQRGDPSRPCP
190 200 210 220 230 240
>>XP_005260503 (OMIM: 612428) PREDICTED: RNA-binding pro (153 aa)
initn: 585 init1: 339 opt: 342 Z-score: 233.6 bits: 49.9 E(85289): 2.8e-06
Smith-Waterman score: 525; 69.2% identity (72.3% similar) in 130 aa overlap (1-98:24-153)
10 20 30
pF1KE0 MHTTQKDTTYTKIFVGGLPYHTTDASLRKYFEVFGEI
:: .:::::.:::::::::::::::::::::: ::.:
XP_005 MLLQPAPCAPSAGFPRPLAAPGAMHGSQKDTTFTKIFVGGLPYHTTDASLRKYFEGFGDI
10 20 30 40 50 60
40 50 60
pF1KE0 EEAVVITDRQTGKSRGYGF--------------------------------VTMADRAAA
::::::::::::::::::: :::::::::
XP_005 EEAVVITDRQTGKSRGYGFGIIFVLEGHISQALNFDGRSWNPGGIFVGEPQVTMADRAAA
70 80 90 100 110 120
70 80 90 100 110 120
pF1KE0 ERACKDPNPIIDGRKANVNLAYLGAKPRIMQPGFAFGVQQLHPALIQRPFGIPAHYVYPQ
:::::::::::::::::::::::::::: .: :
XP_005 ERACKDPNPIIDGRKANVNLAYLGAKPRSLQTG
130 140 150
130 140 150 160 170 180
pF1KE0 AFVQPGVVIPHVQPTAAAASTTPYIDYTGAAYAQYSAAAAAAAAAAAYDQYPYAASPAAA
>>XP_011522588 (OMIM: 607897) PREDICTED: RNA-binding pro (242 aa)
initn: 305 init1: 189 opt: 255 Z-score: 180.6 bits: 40.8 E(85289): 0.0025
Smith-Waterman score: 255; 28.8% identity (57.6% similar) in 229 aa overlap (8-225:3-212)
10 20 30 40 50 60
pF1KE0 MHTTQKDTTYTKIFVGGLPYHTTDASLRKYFEVFGEIEEAVVITDRQTGKSRGYGFVTMA
: ::::::: .:. ....::: ::..:.:... :. :.. ::.::::.
XP_011 MVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFE
10 20 30 40 50
70 80 90 100 110
pF1KE0 DRAAAERACKDPNPIIDGRKANVNLAYLGAKPR-IMQP----GFAFGVQQLHPALIQRPF
.. ..:..:. :... .. . :.:. .: : : : :. :.. .
XP_011 NEDVVEKVCEIHFHEINNKMVECK----KAQPKEVMFPPGTRGRARGLPYTMDAFM---L
60 70 80 90 100
120 130 140 150 160 170
pF1KE0 GIPAHYVYPQAFVQPGVVIPHVQPTAAAASTTPYIDYTGAAYAQYSAAAAAAAAAAAYDQ
:. . ::. . : : :. . . . .:::. .:::.::: ... ..
XP_011 GM-GMLGYPNFVATYGRGYPGFAPSYGYQ----FPGFPAAAYGPVAAAAVAAARGSVLNS
110 120 130 140 150 160
180 190 200 210 220
pF1KE0 Y---PY---AASPAAAGYVTAGGYGYAVQQPITAAAPGTAAAAAAAAAAAAAFGQYQPQQ
: : ::::... . ::. : : .:: .: . :. .. :.:
XP_011 YSAQPNFGAPASPAGSNPARPGGF------P-GANSPGPVADLYGPASQDSGVGNYISAA
170 180 190 200 210
230
pF1KE0 LQTDRMQ
XP_011 SPQPGSGFGHGIAGPLIATAFTNGYH
220 230 240
>>XP_016879638 (OMIM: 607897) PREDICTED: RNA-binding pro (259 aa)
initn: 305 init1: 189 opt: 255 Z-score: 180.4 bits: 40.9 E(85289): 0.0026
Smith-Waterman score: 255; 28.8% identity (57.6% similar) in 229 aa overlap (8-225:20-229)
10 20 30 40
pF1KE0 MHTTQKDTTYTKIFVGGLPYHTTDASLRKYFEVFGEIEEAVVITDRQT
: ::::::: .:. ....::: ::..:.:... :. :
XP_016 MTAGLRAELSGDAGPLKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTT
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 GKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPR-IMQP----GFAFGV
.. ::.::::. .. ..:..:. :... .. . :.:. .: : : : :.
XP_016 NRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECK----KAQPKEVMFPPGTRGRARGL
70 80 90 100 110
110 120 130 140 150 160
pF1KE0 QQLHPALIQRPFGIPAHYVYPQAFVQPGVVIPHVQPTAAAASTTPYIDYTGAAYAQYSAA
:.. .:. . ::. . : : :. . . . .:::. .::
XP_016 PYTMDAFM---LGM-GMLGYPNFVATYGRGYPGFAPSYGYQ----FPGFPAAAYGPVAAA
120 130 140 150 160
170 180 190 200 210
pF1KE0 AAAAAAAAAYDQY---PY---AASPAAAGYVTAGGYGYAVQQPITAAAPGTAAAAAAAAA
:.::: ... ..: : ::::... . ::. : : .:: .: . :.
XP_016 AVAAARGSVLNSYSAQPNFGAPASPAGSNPARPGGF------P-GANSPGPVADLYGPAS
170 180 190 200 210 220
220 230
pF1KE0 AAAAFGQYQPQQLQTDRMQ
.. :.:
XP_016 QDSGVGNYISAASPQPGSGFGHGIAGPLIATAFTNGYH
230 240 250
>>NP_001309179 (OMIM: 607897) RNA-binding protein Musash (324 aa)
initn: 305 init1: 189 opt: 255 Z-score: 179.5 bits: 41.0 E(85289): 0.0029
Smith-Waterman score: 255; 28.8% identity (57.6% similar) in 229 aa overlap (8-225:85-294)
10 20 30
pF1KE0 MHTTQKDTTYTKIFVGGLPYHTTDASLRKYFEVFGEI
: ::::::: .:. ....::: ::..
NP_001 KVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKV
60 70 80 90 100 110
40 50 60 70 80 90
pF1KE0 EEAVVITDRQTGKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPR-IMQ
:.:... :. :.. ::.::::. .. ..:..:. :... .. . :.:. .:
NP_001 EDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECK----KAQPKEVMF
120 130 140 150 160 170
100 110 120 130 140 150
pF1KE0 P----GFAFGVQQLHPALIQRPFGIPAHYVYPQAFVQPGVVIPHVQPTAAAASTTPYIDY
: : : :. :.. .:. . ::. . : : :. . . .
NP_001 PPGTRGRARGLPYTMDAFM---LGM-GMLGYPNFVATYGRGYPGFAPSYGYQ----FPGF
180 190 200 210 220
160 170 180 190 200
pF1KE0 TGAAYAQYSAAAAAAAAAAAYDQY---PY---AASPAAAGYVTAGGYGYAVQQPITAAAP
.:::. .:::.::: ... ..: : ::::... . ::. : : .:
NP_001 PAAAYGPVAAAAVAAARGSVLNSYSAQPNFGAPASPAGSNPARPGGF------P-GANSP
230 240 250 260 270
210 220 230
pF1KE0 GTAAAAAAAAAAAAAFGQYQPQQLQTDRMQ
: .: . :. .. :.:
NP_001 GPVADLYGPASQDSGVGNYISAASPQPGSGFGHGIAGPLIATAFTNGYH
280 290 300 310 320
>>XP_005257071 (OMIM: 607897) PREDICTED: RNA-binding pro (346 aa)
initn: 305 init1: 189 opt: 255 Z-score: 179.2 bits: 41.1 E(85289): 0.003
Smith-Waterman score: 255; 28.8% identity (57.6% similar) in 229 aa overlap (8-225:107-316)
10 20 30
pF1KE0 MHTTQKDTTYTKIFVGGLPYHTTDASLRKYFEVFGEI
: ::::::: .:. ....::: ::..
XP_005 KVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKV
80 90 100 110 120 130
40 50 60 70 80 90
pF1KE0 EEAVVITDRQTGKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPR-IMQ
:.:... :. :.. ::.::::. .. ..:..:. :... .. . :.:. .:
XP_005 EDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECK----KAQPKEVMF
140 150 160 170 180 190
100 110 120 130 140 150
pF1KE0 P----GFAFGVQQLHPALIQRPFGIPAHYVYPQAFVQPGVVIPHVQPTAAAASTTPYIDY
: : : :. :.. .:. . ::. . : : :. . . .
XP_005 PPGTRGRARGLPYTMDAFM---LGM-GMLGYPNFVATYGRGYPGFAPSYGYQ----FPGF
200 210 220 230 240
160 170 180 190 200
pF1KE0 TGAAYAQYSAAAAAAAAAAAYDQY---PY---AASPAAAGYVTAGGYGYAVQQPITAAAP
.:::. .:::.::: ... ..: : ::::... . ::. : : .:
XP_005 PAAAYGPVAAAAVAAARGSVLNSYSAQPNFGAPASPAGSNPARPGGF------P-GANSP
250 260 270 280 290
210 220 230
pF1KE0 GTAAAAAAAAAAAAAFGQYQPQQLQTDRMQ
: .: . :. .. :.:
XP_005 GPVADLYGPASQDSGVGNYISAASPQPGSGFGHGIAGPLIATAFTNGYH
300 310 320 330 340
>>XP_005257072 (OMIM: 607897) PREDICTED: RNA-binding pro (346 aa)
initn: 305 init1: 189 opt: 255 Z-score: 179.2 bits: 41.1 E(85289): 0.003
Smith-Waterman score: 255; 28.8% identity (57.6% similar) in 229 aa overlap (8-225:107-316)
10 20 30
pF1KE0 MHTTQKDTTYTKIFVGGLPYHTTDASLRKYFEVFGEI
: ::::::: .:. ....::: ::..
XP_005 KVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKV
80 90 100 110 120 130
40 50 60 70 80 90
pF1KE0 EEAVVITDRQTGKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPR-IMQ
:.:... :. :.. ::.::::. .. ..:..:. :... .. . :.:. .:
XP_005 EDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECK----KAQPKEVMF
140 150 160 170 180 190
100 110 120 130 140 150
pF1KE0 P----GFAFGVQQLHPALIQRPFGIPAHYVYPQAFVQPGVVIPHVQPTAAAASTTPYIDY
: : : :. :.. .:. . ::. . : : :. . . .
XP_005 PPGTRGRARGLPYTMDAFM---LGM-GMLGYPNFVATYGRGYPGFAPSYGYQ----FPGF
200 210 220 230 240
160 170 180 190 200
pF1KE0 TGAAYAQYSAAAAAAAAAAAYDQY---PY---AASPAAAGYVTAGGYGYAVQQPITAAAP
.:::. .:::.::: ... ..: : ::::... . ::. : : .:
XP_005 PAAAYGPVAAAAVAAARGSVLNSYSAQPNFGAPASPAGSNPARPGGF------P-GANSP
250 260 270 280 290
210 220 230
pF1KE0 GTAAAAAAAAAAAAAFGQYQPQQLQTDRMQ
: .: . :. .. :.:
XP_005 GPVADLYGPASQDSGVGNYISAASPQPGSGFGHGIASIPGCPGKTGRSF
300 310 320 330 340
236 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 18:33:33 2016 done: Wed Nov 2 18:33:34 2016
Total Scan time: 3.780 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]