Result of FASTA (omim) for
pF1KE0657
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0657, 233 aa
1>>>pF1KE0657 233 - 233 aa - 233 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.6693+/-0.000431; mu= -2.0022+/- 0.026
mean_var=220.0931+/-48.897, 0's: 0 Z-trim(117.5): 374 B-trim: 1491 in 3/55
Lambda= 0.086451
statistics sampled from 29049 (29563) to 29049 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.699), E-opt: 0.2 (0.347), width: 16
Scan time: 4.900
The best scores are: opt bits E(85289)
NP_004655 (OMIM: 603380) protein lin-7 homolog A i ( 233) 1492 198.5 8e-51
NP_001311352 (OMIM: 603380) protein lin-7 homolog ( 162) 1052 143.5 2e-34
XP_011537230 (OMIM: 603380) PREDICTED: protein lin ( 186) 1053 143.7 2e-34
NP_060832 (OMIM: 612332) protein lin-7 homolog C [ ( 197) 1039 142.0 7.2e-34
NP_071448 (OMIM: 612331) protein lin-7 homolog B i ( 207) 1038 141.9 8.1e-34
XP_006723386 (OMIM: 612331) PREDICTED: protein lin ( 183) 736 104.2 1.6e-22
NP_001295348 (OMIM: 612331) protein lin-7 homolog ( 137) 334 53.9 1.6e-07
NP_001136172 (OMIM: 603583) disks large homolog 2 ( 749) 278 47.5 7.3e-05
XP_016872775 (OMIM: 603583) PREDICTED: disks large ( 757) 278 47.5 7.3e-05
XP_011543090 (OMIM: 603583) PREDICTED: disks large ( 767) 278 47.5 7.4e-05
XP_016872774 (OMIM: 603583) PREDICTED: disks large ( 796) 278 47.6 7.6e-05
XP_016872773 (OMIM: 603583) PREDICTED: disks large ( 801) 278 47.6 7.6e-05
XP_016872772 (OMIM: 603583) PREDICTED: disks large ( 810) 278 47.6 7.7e-05
XP_016872771 (OMIM: 603583) PREDICTED: disks large ( 811) 278 47.6 7.7e-05
XP_005273868 (OMIM: 603583) PREDICTED: disks large ( 819) 278 47.6 7.8e-05
XP_016872769 (OMIM: 603583) PREDICTED: disks large ( 820) 278 47.6 7.8e-05
XP_016872770 (OMIM: 603583) PREDICTED: disks large ( 820) 278 47.6 7.8e-05
XP_016872768 (OMIM: 603583) PREDICTED: disks large ( 821) 278 47.6 7.8e-05
XP_005273867 (OMIM: 603583) PREDICTED: disks large ( 837) 278 47.6 7.9e-05
XP_016872767 (OMIM: 603583) PREDICTED: disks large ( 839) 278 47.6 7.9e-05
XP_016872766 (OMIM: 603583) PREDICTED: disks large ( 842) 278 47.6 7.9e-05
XP_016872765 (OMIM: 603583) PREDICTED: disks large ( 848) 278 47.6 8e-05
NP_001287912 (OMIM: 603583) disks large homolog 2 ( 852) 278 47.6 8e-05
XP_016872764 (OMIM: 603583) PREDICTED: disks large ( 857) 278 47.6 8e-05
XP_016872763 (OMIM: 603583) PREDICTED: disks large ( 866) 278 47.6 8.1e-05
NP_001355 (OMIM: 603583) disks large homolog 2 iso ( 870) 278 47.6 8.1e-05
XP_016872762 (OMIM: 603583) PREDICTED: disks large ( 871) 278 47.6 8.1e-05
XP_016872761 (OMIM: 603583) PREDICTED: disks large ( 871) 278 47.6 8.1e-05
XP_016872760 (OMIM: 603583) PREDICTED: disks large ( 872) 278 47.6 8.1e-05
XP_016872759 (OMIM: 603583) PREDICTED: disks large ( 873) 278 47.6 8.2e-05
XP_016872758 (OMIM: 603583) PREDICTED: disks large ( 880) 278 47.6 8.2e-05
XP_016872757 (OMIM: 603583) PREDICTED: disks large ( 883) 278 47.6 8.2e-05
XP_016872756 (OMIM: 603583) PREDICTED: disks large ( 884) 278 47.6 8.2e-05
XP_016872755 (OMIM: 603583) PREDICTED: disks large ( 891) 278 47.6 8.3e-05
XP_011543084 (OMIM: 603583) PREDICTED: disks large ( 891) 278 47.6 8.3e-05
XP_016872754 (OMIM: 603583) PREDICTED: disks large ( 903) 278 47.6 8.4e-05
XP_016872753 (OMIM: 603583) PREDICTED: disks large ( 904) 278 47.6 8.4e-05
XP_016872752 (OMIM: 603583) PREDICTED: disks large ( 905) 278 47.6 8.4e-05
NP_001193698 (OMIM: 603583) disks large homolog 2 ( 909) 278 47.6 8.4e-05
XP_016872751 (OMIM: 603583) PREDICTED: disks large ( 923) 278 47.6 8.5e-05
XP_016872750 (OMIM: 603583) PREDICTED: disks large ( 955) 278 47.6 8.7e-05
XP_016872749 (OMIM: 603583) PREDICTED: disks large ( 968) 278 47.6 8.8e-05
XP_016872748 (OMIM: 603583) PREDICTED: disks large ( 969) 278 47.6 8.8e-05
NP_001136171 (OMIM: 603583) disks large homolog 2 ( 975) 278 47.6 8.9e-05
XP_016872747 (OMIM: 603583) PREDICTED: disks large ( 985) 278 47.6 8.9e-05
XP_011543082 (OMIM: 603583) PREDICTED: disks large (1007) 278 47.6 9.1e-05
XP_016872746 (OMIM: 603583) PREDICTED: disks large (1025) 278 47.7 9.2e-05
XP_011543080 (OMIM: 603583) PREDICTED: disks large (1025) 278 47.7 9.2e-05
XP_016872745 (OMIM: 603583) PREDICTED: disks large (1026) 278 47.7 9.2e-05
XP_016872744 (OMIM: 603583) PREDICTED: disks large (1026) 278 47.7 9.2e-05
>>NP_004655 (OMIM: 603380) protein lin-7 homolog A isofo (233 aa)
initn: 1492 init1: 1492 opt: 1492 Z-score: 1033.5 bits: 198.5 E(85289): 8e-51
Smith-Waterman score: 1492; 100.0% identity (100.0% similar) in 233 aa overlap (1-233:1-233)
10 20 30 40 50 60
pF1KE0 MLKPSVTSAPTADMATLTVVQPLTLDRDVARAIELLEKLQESGEVPVHKLQSLKKVLQSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MLKPSVTSAPTADMATLTVVQPLTLDRDVARAIELLEKLQESGEVPVHKLQSLKKVLQSE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 FCTAIREVYQYMHETITVNGCPEFRARATAKATVAAFAASEGHSHPRVVELPKTDEGLGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FCTAIREVYQYMHETITVNGCPEFRARATAKATVAAFAASEGHSHPRVVELPKTDEGLGF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 NVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKD
130 140 150 160 170 180
190 200 210 220 230
pF1KE0 SVKLVVRYTPKVLEEMEARFEKLRTARRRQQQQLLIQQQQQQQQQQTQQNHMS
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SVKLVVRYTPKVLEEMEARFEKLRTARRRQQQQLLIQQQQQQQQQQTQQNHMS
190 200 210 220 230
>>NP_001311352 (OMIM: 603380) protein lin-7 homolog A is (162 aa)
initn: 1052 init1: 1052 opt: 1052 Z-score: 739.0 bits: 143.5 E(85289): 2e-34
Smith-Waterman score: 1052; 100.0% identity (100.0% similar) in 162 aa overlap (72-233:1-162)
50 60 70 80 90 100
pF1KE0 SGEVPVHKLQSLKKVLQSEFCTAIREVYQYMHETITVNGCPEFRARATAKATVAAFAASE
::::::::::::::::::::::::::::::
NP_001 MHETITVNGCPEFRARATAKATVAAFAASE
10 20 30
110 120 130 140 150 160
pF1KE0 GHSHPRVVELPKTDEGLGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GHSHPRVVELPKTDEGLGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGV
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE0 SVEGEHHEKAVELLKAAKDSVKLVVRYTPKVLEEMEARFEKLRTARRRQQQQLLIQQQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVEGEHHEKAVELLKAAKDSVKLVVRYTPKVLEEMEARFEKLRTARRRQQQQLLIQQQQQ
100 110 120 130 140 150
230
pF1KE0 QQQQQTQQNHMS
::::::::::::
NP_001 QQQQQTQQNHMS
160
>>XP_011537230 (OMIM: 603380) PREDICTED: protein lin-7 h (186 aa)
initn: 1053 init1: 1053 opt: 1053 Z-score: 738.9 bits: 143.7 E(85289): 2e-34
Smith-Waterman score: 1053; 98.2% identity (100.0% similar) in 166 aa overlap (1-166:1-166)
10 20 30 40 50 60
pF1KE0 MLKPSVTSAPTADMATLTVVQPLTLDRDVARAIELLEKLQESGEVPVHKLQSLKKVLQSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLKPSVTSAPTADMATLTVVQPLTLDRDVARAIELLEKLQESGEVPVHKLQSLKKVLQSE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 FCTAIREVYQYMHETITVNGCPEFRARATAKATVAAFAASEGHSHPRVVELPKTDEGLGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FCTAIREVYQYMHETITVNGCPEFRARATAKATVAAFAASEGHSHPRVVELPKTDEGLGF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 NVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKD
:::::::::::::::::::::::::::::::::::::::::..::.
XP_011 NVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVALEGKLLDQTSDSHKFETV
130 140 150 160 170 180
190 200 210 220 230
pF1KE0 SVKLVVRYTPKVLEEMEARFEKLRTARRRQQQQLLIQQQQQQQQQQTQQNHMS
XP_011 LQNPST
>>NP_060832 (OMIM: 612332) protein lin-7 homolog C [Homo (197 aa)
initn: 1038 init1: 1038 opt: 1039 Z-score: 729.1 bits: 142.0 E(85289): 7.2e-34
Smith-Waterman score: 1039; 79.3% identity (94.4% similar) in 198 aa overlap (14-211:1-196)
10 20 30 40 50 60
pF1KE0 MLKPSVTSAPTADMATLTVVQPLTLDRDVARAIELLEKLQESGEVPVHKLQSLKKVLQSE
::.: .:. :.::. ::::::::::.::::: .:::.:..:::::
NP_060 MAALG--EPVRLERDICRAIELLEKLQRSGEVPPQKLQALQRVLQSE
10 20 30 40
70 80 90 100 110 120
pF1KE0 FCTAIREVYQYMHETITVNGCPEFRARATAKATVAAFAASEGHSHPRVVELPKTDEGLGF
::.:.::::....::. ... :: :: :::::::::::::::::::::::::::.:::::
NP_060 FCNAVREVYEHVYETVDISSSPEVRANATAKATVAAFAASEGHSHPRVVELPKTEEGLGF
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE0 NVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKD
:.:::::::::::::::::::.:.::::::::::::::::::::::::::::::::::.
NP_060 NIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQG
110 120 130 140 150 160
190 200 210 220 230
pF1KE0 SVKLVVRYTPKVLEEMEARFEKLRTARRRQQQQLLIQQQQQQQQQQTQQNHMS
.::::::::::::::::.::::.:.:.::::
NP_060 KVKLVVRYTPKVLEEMESRFEKMRSAKRRQQT
170 180 190
>>NP_071448 (OMIM: 612331) protein lin-7 homolog B isofo (207 aa)
initn: 1082 init1: 1028 opt: 1038 Z-score: 728.1 bits: 141.9 E(85289): 8.1e-34
Smith-Waterman score: 1038; 78.5% identity (95.5% similar) in 200 aa overlap (14-213:1-198)
10 20 30 40 50 60
pF1KE0 MLKPSVTSAPTADMATLTVVQPLTLDRDVARAIELLEKLQESGEVPVHKLQSLKKVLQSE
::.: :.:: :.:::.::.::::.::.:::.: .:::.:..::::.
NP_071 MAAL--VEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSR
10 20 30 40
70 80 90 100 110 120
pF1KE0 FCTAIREVYQYMHETITVNGCPEFRARATAKATVAAFAASEGHSHPRVVELPKTDEGLGF
::.::::::. ...:. ..: :.::.::::::::::.:::::.::::::::::::::::
NP_071 FCSAIREVYEQLYDTLDITGSAEIRAHATAKATVAAFTASEGHAHPRVVELPKTDEGLGF
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE0 NVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKD
:.::::::::::::::.::::::.::::::::::::::::::::::.:::::::::::.
NP_071 NIMGGKEQNSPIYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEGEQHEKAVELLKAAQG
110 120 130 140 150 160
190 200 210 220 230
pF1KE0 SVKLVVRYTPKVLEEMEARFEKLRTARRRQQQQLLIQQQQQQQQQQTQQNHMS
::::::::::.:::::::::::.:.::::::.:
NP_071 SVKLVVRYTPRVLEEMEARFEKMRSARRRQQHQSYSSLESRG
170 180 190 200
>>XP_006723386 (OMIM: 612331) PREDICTED: protein lin-7 h (183 aa)
initn: 1000 init1: 733 opt: 736 Z-score: 525.3 bits: 104.2 E(85289): 1.6e-22
Smith-Waterman score: 904; 73.0% identity (85.5% similar) in 200 aa overlap (14-213:1-174)
10 20 30 40 50 60
pF1KE0 MLKPSVTSAPTADMATLTVVQPLTLDRDVARAIELLEKLQESGEVPVHKLQSLKKVLQSE
::.: :.:: :.:::.::.::::.::.:::.: .:::.:..::::.
XP_006 MAAL--VEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSR
10 20 30 40
70 80 90 100 110 120
pF1KE0 FCTAIREVYQYMHETITVNGCPEFRARATAKATVAAFAASEGHSHPRVVELPKTDEGLGF
::.:::: ::::::.:::::.::::::::::::::::
XP_006 FCSAIRE------------------------ATVAAFTASEGHAHPRVVELPKTDEGLGF
50 60 70 80
130 140 150 160 170 180
pF1KE0 NVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKD
:.::::::::::::::.::::::.::::::::::::::::::::::.:::::::::::.
XP_006 NIMGGKEQNSPIYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEGEQHEKAVELLKAAQG
90 100 110 120 130 140
190 200 210 220 230
pF1KE0 SVKLVVRYTPKVLEEMEARFEKLRTARRRQQQQLLIQQQQQQQQQQTQQNHMS
::::::::::.:::::::::::.:.::::::.:
XP_006 SVKLVVRYTPRVLEEMEARFEKMRSARRRQQHQSYSSLESRG
150 160 170 180
>>NP_001295348 (OMIM: 612331) protein lin-7 homolog B is (137 aa)
initn: 631 init1: 304 opt: 334 Z-score: 256.0 bits: 53.9 E(85289): 1.6e-07
Smith-Waterman score: 442; 46.0% identity (60.5% similar) in 200 aa overlap (14-213:1-128)
10 20 30 40 50 60
pF1KE0 MLKPSVTSAPTADMATLTVVQPLTLDRDVARAIELLEKLQESGEVPVHKLQSLKKVLQSE
::.: :.:: :.:::.::.::::.::.:::.: .:::.:..::::.
NP_001 MAAL--VEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSR
10 20 30 40
70 80 90 100 110 120
pF1KE0 FCTAIREVYQYMHETITVNGCPEFRARATAKATVAAFAASEGHSHPRVVELPKTDEGLGF
::.::::::. ...:. ..: :.::.::::
NP_001 FCSAIREVYEQLYDTLDITGSAEIRAHATAK-----------------------------
50 60 70
130 140 150 160 170 180
pF1KE0 NVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKD
:::::.:::::::::::.
NP_001 -----------------------------------------SVEGEQHEKAVELLKAAQG
80 90
190 200 210 220 230
pF1KE0 SVKLVVRYTPKVLEEMEARFEKLRTARRRQQQQLLIQQQQQQQQQQTQQNHMS
::::::::::.:::::::::::.:.::::::.:
NP_001 SVKLVVRYTPRVLEEMEARFEKMRSARRRQQHQSYSSLESRG
100 110 120 130
>>NP_001136172 (OMIM: 603583) disks large homolog 2 isof (749 aa)
initn: 215 init1: 215 opt: 278 Z-score: 208.3 bits: 47.5 E(85289): 7.3e-05
Smith-Waterman score: 278; 40.2% identity (71.8% similar) in 117 aa overlap (88-204:298-413)
60 70 80 90 100 110
pF1KE0 QSEFCTAIREVYQYMHETITVNGCPEFRARATAKATVAAFAASEGHSHPRVVELPKTDEG
:: . ... : ...:: : : : . :
NP_001 LPPISPGRYSPIPKHMLVDDDYTSHSQHSTATRQPSMTLQRAVSLEGEPRKVVLHKGSTG
270 280 290 300 310 320
120 130 140 150 160 170
pF1KE0 LGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKA
::::..:: :.. :..: :. :: :. : :.::::.:::::....: ::.:. ::.
NP_001 LGFNIVGG-EDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKG
330 340 350 360 370 380
180 190 200 210 220 230
pF1KE0 AKDSVKLVVRYTPKVLEEMEARFEKLRTARRRQQQQLLIQQQQQQQQQQTQQNHMS
: ..: ....: :. ..::... ::
NP_001 AGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVRAMFDYDK
390 400 410 420 430 440
>>XP_016872775 (OMIM: 603583) PREDICTED: disks large hom (757 aa)
initn: 215 init1: 215 opt: 278 Z-score: 208.3 bits: 47.5 E(85289): 7.3e-05
Smith-Waterman score: 278; 40.2% identity (71.8% similar) in 117 aa overlap (88-204:274-389)
60 70 80 90 100 110
pF1KE0 QSEFCTAIREVYQYMHETITVNGCPEFRARATAKATVAAFAASEGHSHPRVVELPKTDEG
:: . ... : ...:: : : : . :
XP_016 KSFLLSAPYSHYHLGLLPDSEMTSHSQHSTATRQPSMTLQRAVSLEGEPRKVVLHKGSTG
250 260 270 280 290 300
120 130 140 150 160 170
pF1KE0 LGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKA
::::..:: :.. :..: :. :: :. : :.::::.:::::....: ::.:. ::.
XP_016 LGFNIVGG-EDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKG
310 320 330 340 350 360
180 190 200 210 220 230
pF1KE0 AKDSVKLVVRYTPKVLEEMEARFEKLRTARRRQQQQLLIQQQQQQQQQQTQQNHMS
: ..: ....: :. ..::... ::
XP_016 AGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVRAMFDYDK
370 380 390 400 410 420
>>XP_011543090 (OMIM: 603583) PREDICTED: disks large hom (767 aa)
initn: 215 init1: 215 opt: 278 Z-score: 208.2 bits: 47.5 E(85289): 7.4e-05
Smith-Waterman score: 278; 40.2% identity (71.8% similar) in 117 aa overlap (88-204:316-431)
60 70 80 90 100 110
pF1KE0 QSEFCTAIREVYQYMHETITVNGCPEFRARATAKATVAAFAASEGHSHPRVVELPKTDEG
:: . ... : ...:: : : : . :
XP_011 LPPISPGRYSPIPKHMLVDDDYTSHSQHSTATRQPSMTLQRAVSLEGEPRKVVLHKGSTG
290 300 310 320 330 340
120 130 140 150 160 170
pF1KE0 LGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKA
::::..:: :.. :..: :. :: :. : :.::::.:::::....: ::.:. ::.
XP_011 LGFNIVGG-EDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKG
350 360 370 380 390 400
180 190 200 210 220 230
pF1KE0 AKDSVKLVVRYTPKVLEEMEARFEKLRTARRRQQQQLLIQQQQQQQQQQTQQNHMS
: ..: ....: :. ..::... ::
XP_011 AGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVRAMFDYDK
410 420 430 440 450 460
233 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 18:40:26 2016 done: Wed Nov 2 18:40:27 2016
Total Scan time: 4.900 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]