Result of FASTA (ccds) for
pF1KE0646
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0646, 380 aa
1>>>pF1KE0646 380 - 380 aa - 380 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.4007+/-0.000749; mu= 8.0942+/- 0.045
mean_var=131.0079+/-25.953, 0's: 0 Z-trim(113.0): 25 B-trim: 0 in 0/52
Lambda= 0.112054
statistics sampled from 13653 (13673) to 13653 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.775), E-opt: 0.2 (0.42), width: 16
Scan time: 2.930
The best scores are: opt bits E(32554)
CCDS14614.1 SASH3 gene_id:54440|Hs108|chrX ( 380) 2517 417.7 8.5e-117
CCDS5212.1 SASH1 gene_id:23328|Hs108|chr6 (1247) 834 145.9 1.8e-34
CCDS42906.1 SAMSN1 gene_id:64092|Hs108|chr21 ( 373) 821 143.5 2.9e-34
CCDS58786.1 SAMSN1 gene_id:64092|Hs108|chr21 ( 441) 816 142.8 5.8e-34
CCDS74774.1 SAMSN1 gene_id:64092|Hs108|chr21 ( 304) 755 132.8 3.9e-31
>>CCDS14614.1 SASH3 gene_id:54440|Hs108|chrX (380 aa)
initn: 2517 init1: 2517 opt: 2517 Z-score: 2210.3 bits: 417.7 E(32554): 8.5e-117
Smith-Waterman score: 2517; 100.0% identity (100.0% similar) in 380 aa overlap (1-380:1-380)
10 20 30 40 50 60
pF1KE0 MLRRKPSNASEKEPTQKKKLSLQRSSSFKDFAKSKPSSPVVSEKEFNLDDNIPEDDSGVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 MLRRKPSNASEKEPTQKKKLSLQRSSSFKDFAKSKPSSPVVSEKEFNLDDNIPEDDSGVP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 TPEDAGKSGKKLGKKWRAVISRTMNRKMGKMMVKALSEEMADTLEEGSASPTSPDYSLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 TPEDAGKSGKKLGKKWRAVISRTMNRKMGKMMVKALSEEMADTLEEGSASPTSPDYSLDS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 PGPEKMALAFSEQEEHELPVLSRQASTGSELCSPSPGSGSFGEEPPAPQYTGPFCGRARV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 PGPEKMALAFSEQEEHELPVLSRQASTGSELCSPSPGSGSFGEEPPAPQYTGPFCGRARV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 HTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDVLPEEAVGHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 HTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDVLPEEAVGHA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 RPSRRQSKGKRPKPKTLHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHLNELNIMDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 RPSRRQSKGKRPKPKTLHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHLNELNIMDP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 QHRAKLLTAAELLLDYDTGSEEAEEGAESSQEPVAHTVSEPKVDIPRDSGCFEGSESGRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 QHRAKLLTAAELLLDYDTGSEEAEEGAESSQEPVAHTVSEPKVDIPRDSGCFEGSESGRD
310 320 330 340 350 360
370 380
pF1KE0 DAELAGTEEQLQGLSLAGAP
::::::::::::::::::::
CCDS14 DAELAGTEEQLQGLSLAGAP
370 380
>>CCDS5212.1 SASH1 gene_id:23328|Hs108|chr6 (1247 aa)
initn: 830 init1: 694 opt: 834 Z-score: 732.2 bits: 145.9 E(32554): 1.8e-34
Smith-Waterman score: 834; 45.6% identity (67.0% similar) in 351 aa overlap (20-357:400-733)
10 20 30 40
pF1KE0 MLRRKPSNASEKEPTQKKKLSLQRSSSFKDFAKSKPSSPVVSEKEFNLD
:: :. :: : .. : : :. : :
CCDS52 GTFFSYPEEEKAQKVSRSLTEGEMKKGLGSLSHGRTCSFGGFDLTNRSLHVGSN---NSD
370 380 390 400 410 420
50 60 70 80 90 100
pF1KE0 DNIPEDD----SGVPTPEDAGKSGKKLGKKWRAVISRTMNRKMGKMMVKALSEEMA--DT
: : . .: : .:::: ..: ..:: ..:.: . ...::. . :
CCDS52 PMGKEGDFVYKEVIKSPT---ASRISLGKKVKSV-KETMRKRMSKKYSSSVSEQDSGLDG
430 440 450 460 470 480
110 120 130 140 150
pF1KE0 LEEGSASPTSPD-YSLDSP-----GP-EKMALAFSEQEEHELPVLSRQASTGSELCSPSP
. :: :..:: ::.: : :.. ..: : ..: :. :. : .
CCDS52 MP-GSPPPSQPDPEHLDKPKLKAGGSVESLRSSLSGQSSMSGQTVSTTDSSTSNRESVKS
490 500 510 520 530 540
160 170 180 190 200 210
pF1KE0 GSGSFGEEPPAPQYTGPFCGRARVHTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGL
.:. :::: : ::::::::::::::::::: :::::.:::.:.:: :::.:::.::
CCDS52 EDGD-DEEPP---YRGPFCGRARVHTDFTPSPYDTDSLKLKKGDIIDIISKPPMGTWMGL
550 560 570 580 590
220 230 240 250 260 270
pF1KE0 LNGKVGSFKFIYVDVLPEEAVGHARPSRRQSKGKRPKPKTLHELLERIGLEEHTSTLLLN
::.:::.::::::::: :. ::.::. ::. :.::....::.::.:.:: :.:.:
CCDS52 LNNKVGTFKFIYVDVLSEDEEKPKRPTRRRRKGRPPQPKSVEDLLDRINLKEHMPTFLFN
600 610 620 630 640 650
280 290 300 310 320 330
pF1KE0 GYQTLEDFKELRETHLNELNIMDPQHRAKLLTAAELLLDYDTGSEEAEEGAESSQEPVAH
::. :. :: :.: :.:::: ::.::: ::::.::: .::..:... .::: .
CCDS52 GYEDLDTFKLLEEEDLDELNIRDPEHRAVLLTAVELLQEYDSNSDQS-----GSQEKLLV
660 670 680 690 700 710
340 350 360 370 380
pF1KE0 TVSEPKVDIPRDSGCFEGSESGRDDAELAGTEEQLQGLSLAGAP
. . ::::::.:.::.
CCDS52 DSQGLSGCSPRDSGCYESSENLENGKTRKASLLSAKSSTEPSLKSFSRNQLGNYPTLPLM
720 730 740 750 760 770
>>CCDS42906.1 SAMSN1 gene_id:64092|Hs108|chr21 (373 aa)
initn: 812 init1: 368 opt: 821 Z-score: 728.7 bits: 143.5 E(32554): 2.9e-34
Smith-Waterman score: 886; 45.7% identity (68.7% similar) in 374 aa overlap (1-363:1-355)
10 20 30 40 50 60
pF1KE0 MLRRKPSNASEKEPTQKKKLSLQRSSSFKDFAKSKPSSPVVSEKEFNLDDNIPEDDSGVP
::.:::::.:::: :: : ::::: .: . . .: . . .. : . ::
CCDS42 MLKRKPSNVSEKEKHQKPK----RSSSFGNFDRFRNNSLSKPDDSTEAHEGDPTNGSGEQ
10 20 30 40 50
70 80 90 100 110
pF1KE0 TPEDAGKSGKKLGKKWRAVISRTMNRKMGKMMVKALSEEMADTLEEG-SASPTSPDYSLD
. ....: :::: :: :: ::..:.:: ..:::::: . :.: .: : . .
CCDS42 SK--TSNNGGGLGKKMRA-ISWTMKKKVGKKYIKALSEEKDE--EDGENAHPYRNSDPVI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 SPGPEKMALAFSEQEEHELPVLSRQASTGSELCSPSPGS-GSFGEEPPAPQYTGPFCGRA
. ::..: :.. . ....:.: :: . .. :: . .: :.:::::::
CCDS42 GTHTEKVSLKASDSMDSLYS--GQSSSSGITSCSDGTSNRDSFRLDDDGP-YSGPFCGRA
120 130 140 150 160
180 190 200 210 220 230
pF1KE0 RVHTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDVLPEEAVG
:::::::::::: ::::..:::.:.:: : :.: : :.::.:::.::::::::. :: ..
CCDS42 RVHTDFTPSPYDTDSLKIKKGDIIDIICKTPMGMWTGMLNNKVGNFKFIYVDVISEEEAA
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE0 HAR-PSRRQSKGKRPKPKTLHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHLNELNI
. . :.:..: : :::.:.:::: :.:.:::::::::.::::.:...:.:: ::::
CCDS42 PKKIKANRRSNSK--KSKTLQEFLERIHLQEYTSTLLLNGYETLEDLKDIKESHLIELNI
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE0 MDPQHRAKLLTAAELLLDYDTGSEEAEEGAESSQEPVAHT--VSEPKV---DIPRDSGCF
.:. : .::.::: .:. :: . :. ::.. . .: : : ::::::.
CCDS42 ENPDDRRRLLSAAENFLE-----EEIIQEQENEPEPLSLSSDISLNKSQLDDCPRDSGCY
290 300 310 320 330 340
360 370 380
pF1KE0 --EG-SESGRDDAELAGTEEQLQGLSLAGAP
: :..:..: :
CCDS42 ISSGNSDNGKEDLESENLSDMVHKIIITEPSD
350 360 370
>>CCDS58786.1 SAMSN1 gene_id:64092|Hs108|chr21 (441 aa)
initn: 745 init1: 368 opt: 816 Z-score: 723.2 bits: 142.8 E(32554): 5.8e-34
Smith-Waterman score: 816; 44.7% identity (68.7% similar) in 351 aa overlap (24-363:88-423)
10 20 30 40 50
pF1KE0 MLRRKPSNASEKEPTQKKKLSLQRSSSFKDFAKSKPSSPVVSEKEFNLDDNIP
::::: .: . . .: . . .. :
CCDS58 QVGPWDHCSSCIRHTRLKSSCSDMDLLHSWRSSSFGNFDRFRNNSLSKPDDSTEAHEGDP
60 70 80 90 100 110
60 70 80 90 100 110
pF1KE0 EDDSGVPTPEDAGKSGKKLGKKWRAVISRTMNRKMGKMMVKALSEEMADTLEEG-SASPT
. :: . ....: :::: :: :: ::..:.:: ..:::::: . :.: .: :
CCDS58 TNGSGEQSK--TSNNGGGLGKKMRA-ISWTMKKKVGKKYIKALSEEKDE--EDGENAHPY
120 130 140 150 160 170
120 130 140 150 160 170
pF1KE0 SPDYSLDSPGPEKMALAFSEQEEHELPVLSRQASTGSELCSPSPGS-GSFGEEPPAPQYT
. . . ::..: :.. . ....:.: :: . .. :: . .: :.
CCDS58 RNSDPVIGTHTEKVSLKASDSMDSLYS--GQSSSSGITSCSDGTSNRDSFRLDDDGP-YS
180 190 200 210 220
180 190 200 210 220 230
pF1KE0 GPFCGRARVHTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDV
::::::::::::::::::: ::::..:::.:.:: : :.: : :.::.:::.::::::::
CCDS58 GPFCGRARVHTDFTPSPYDTDSLKIKKGDIIDIICKTPMGMWTGMLNNKVGNFKFIYVDV
230 240 250 260 270 280
240 250 260 270 280 290
pF1KE0 LPEEAVGHAR-PSRRQSKGKRPKPKTLHELLERIGLEEHTSTLLLNGYQTLEDFKELRET
. :: .. . . :.:..: : :::.:.:::: :.:.:::::::::.::::.:...:.
CCDS58 ISEEEAAPKKIKANRRSNSK--KSKTLQEFLERIHLQEYTSTLLLNGYETLEDLKDIKES
290 300 310 320 330 340
300 310 320 330 340
pF1KE0 HLNELNIMDPQHRAKLLTAAELLLDYDTGSEEAEEGAESSQEPVAHT--VSEPKV---DI
:: :::: .:. : .::.::: .:. :: . :. ::.. . .: : :
CCDS58 HLIELNIENPDDRRRLLSAAENFLE-----EEIIQEQENEPEPLSLSSDISLNKSQLDDC
350 360 370 380 390 400
350 360 370 380
pF1KE0 PRDSGCF--EG-SESGRDDAELAGTEEQLQGLSLAGAP
::::::. : :..:..: :
CCDS58 PRDSGCYISSGNSDNGKEDLESENLSDMVHKIIITEPSD
410 420 430 440
>>CCDS74774.1 SAMSN1 gene_id:64092|Hs108|chr21 (304 aa)
initn: 710 init1: 368 opt: 755 Z-score: 672.4 bits: 132.8 E(32554): 3.9e-31
Smith-Waterman score: 755; 47.5% identity (71.2% similar) in 295 aa overlap (80-363:4-286)
50 60 70 80 90 100
pF1KE0 DNIPEDDSGVPTPEDAGKSGKKLGKKWRAVISRTMNRKMGKMMVKALSEEMADTLEEG-S
:: ::..:.:: ..:::::: . :.: .
CCDS74 MRAISWTMKKKVGKKYIKALSEEKDE--EDGEN
10 20 30
110 120 130 140 150 160
pF1KE0 ASPTSPDYSLDSPGPEKMALAFSEQEEHELPVLSRQASTGSELCSPSPGS-GSFGEEPPA
: : . . . ::..: :.. . ....:.: :: . .. :: . .
CCDS74 AHPYRNSDPVIGTHTEKVSLKASDSMDSLYS--GQSSSSGITSCSDGTSNRDSFRLDDDG
40 50 60 70 80
170 180 190 200 210 220
pF1KE0 PQYTGPFCGRARVHTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFI
: :.::::::::::::::::::: ::::..:::.:.:: : :.: : :.::.:::.::::
CCDS74 P-YSGPFCGRARVHTDFTPSPYDTDSLKIKKGDIIDIICKTPMGMWTGMLNNKVGNFKFI
90 100 110 120 130 140
230 240 250 260 270 280
pF1KE0 YVDVLPEEAVGHAR-PSRRQSKGKRPKPKTLHELLERIGLEEHTSTLLLNGYQTLEDFKE
::::. :: .. . . :.:..: : :::.:.:::: :.:.:::::::::.::::.:.
CCDS74 YVDVISEEEAAPKKIKANRRSNSK--KSKTLQEFLERIHLQEYTSTLLLNGYETLEDLKD
150 160 170 180 190 200
290 300 310 320 330 340
pF1KE0 LRETHLNELNIMDPQHRAKLLTAAELLLDYDTGSEEAEEGAESSQEPVAHT--VSEPKV-
..:.:: :::: .:. : .::.::: .:. :: . :. ::.. . .: :
CCDS74 IKESHLIELNIENPDDRRRLLSAAENFLE-----EEIIQEQENEPEPLSLSSDISLNKSQ
210 220 230 240 250 260
350 360 370 380
pF1KE0 --DIPRDSGCF--EG-SESGRDDAELAGTEEQLQGLSLAGAP
: ::::::. : :..:..: :
CCDS74 LDDCPRDSGCYISSGNSDNGKEDLESENLSDMVHKIIITEPSD
270 280 290 300
380 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 19:09:29 2016 done: Wed Nov 2 19:09:30 2016
Total Scan time: 2.930 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]