FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0645, 217 aa
  1>>>pF1KE0645 217 - 217 aa - 217 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.5848+/-0.00118; mu= 1.8557+/- 0.068
 mean_var=214.2177+/-48.253, 0's: 0 Z-trim(108.0): 192  B-trim: 0 in 0/50
 Lambda= 0.087629
 statistics sampled from 9720 (9952) to 9720 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.695), E-opt: 0.2 (0.306), width:  16
 Scan time:  1.530

The best scores are:                                      opt bits E(32554)
CCDS11202.1 GRAP gene_id:10750|Hs108|chr17         ( 217) 1484 200.3 7.8e-52
CCDS11721.1 GRB2 gene_id:2885|Hs108|chr17          ( 217)  930 130.2 9.5e-31
CCDS45627.1 GRAPL gene_id:400581|Hs108|chr17       ( 118)  660 95.8 1.2e-20
CCDS82085.1 GRAP gene_id:10750|Hs108|chr17         ( 205)  662 96.3 1.4e-20
CCDS13999.1 GRAP2 gene_id:9402|Hs108|chr22         ( 330)  542 81.4 7.3e-16


>>CCDS11202.1 GRAP gene_id:10750|Hs108|chr17              (217 aa)
 initn: 1484 init1: 1484 opt: 1484  Z-score: 1044.0  bits: 200.3 E(32554): 7.8e-52
Smith-Waterman score: 1484; 100.0% identity (100.0% similar) in 217 aa overlap (1-217:1-217)

               10        20        30        40        50        60
pF1KE0 MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPW
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 YSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 YSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYFL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 WEEKFNSLNELVDFYRTTTIAKKRQIFLRDEEPLLKSPGACFAQAQFDFSAQDPSQLSFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 WEEKFNSLNELVDFYRTTTIAKKRQIFLRDEEPLLKSPGACFAQAQFDFSAQDPSQLSFR
              130       140       150       160       170       180

              190       200       210       
pF1KE0 RGDIIEVLERPDPHWWRGRSCGRVGFFPRSYVQPVHL
       :::::::::::::::::::::::::::::::::::::
CCDS11 RGDIIEVLERPDPHWWRGRSCGRVGFFPRSYVQPVHL
              190       200       210       

>>CCDS11721.1 GRB2 gene_id:2885|Hs108|chr17               (217 aa)
 initn: 934 init1: 724 opt: 930  Z-score: 665.5  bits: 130.2 E(32554): 9.5e-31
Smith-Waterman score: 930; 59.7% identity (85.6% similar) in 216 aa overlap (1-216:1-214)

               10        20        30        40        50        60
pF1KE0 MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPW
       ::..: :.:.:: .:::.:..:: ::.:: : ::::::::: : .::::::::..:::::
CCDS11 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 YSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYFL
       . :.: :  :::.: :. : ::::::::::.::.::.::..:..::::::::...:::::
CCDS11 FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 WEEKFNSLNELVDFYRTTTIAKKRQIFLRDEEPLLKSPGACFAQAQFDFSAQDPSQLSFR
       :  ::::::::::..:.:......:::::: : . ..:   ..:: :::. :. ..:.::
CCDS11 WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQP--TYVQALFDFDPQEDGELGFR
              130       140       150         160       170        

              190       200       210         
pF1KE0 RGDIIEVLERPDPHWWRGRSCGRVGFFPRSYVQPVHL  
       :::.:.:..  ::.::.:   :..:.:::.:: ::.   
CCDS11 RGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
      180       190       200       210       

>>CCDS45627.1 GRAPL gene_id:400581|Hs108|chr17            (118 aa)
 initn: 660 init1: 660 opt: 660  Z-score: 484.2  bits: 95.8 E(32554): 1.2e-20
Smith-Waterman score: 660; 100.0% identity (100.0% similar) in 100 aa overlap (1-100:1-100)

               10        20        30        40        50        60
pF1KE0 MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPW
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 YSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYFL
       ::::::::::::::::::::::::::::::::::::::::                    
CCDS45 YSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNNRAQRGPCLGPKSHSRLG  
               70        80        90       100       110          

              130       140       150       160       170       180
pF1KE0 WEEKFNSLNELVDFYRTTTIAKKRQIFLRDEEPLLKSPGACFAQAQFDFSAQDPSQLSFR

>>CCDS82085.1 GRAP gene_id:10750|Hs108|chr17              (205 aa)
 initn: 680 init1: 662 opt: 662  Z-score: 482.7  bits: 96.3 E(32554): 1.4e-20
Smith-Waterman score: 662; 99.0% identity (100.0% similar) in 101 aa overlap (1-101:1-101)

               10        20        30        40        50        60
pF1KE0 MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPW
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 YSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYFL
       ::::::::::::::::::::::::::::::::::::::::.                   
CCDS82 YSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNHLGPALPRPSLTSQPRTPRS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 WEEKFNSLNELVDFYRTTTIAKKRQIFLRDEEPLLKSPGACFAQAQFDFSAQDPSQLSFR
                                                                   
CCDS82 SASAVATSLRSWSAQTPTGGGAGPAGALASSHGVTCSPCTCEQPGGRSGQRAFLQELRSR
              130       140       150       160       170       180

>>CCDS13999.1 GRAP2 gene_id:9402|Hs108|chr22              (330 aa)
 initn: 676 init1: 326 opt: 542  Z-score: 398.2  bits: 81.4 E(32554): 7.3e-16
Smith-Waterman score: 542; 52.7% identity (82.7% similar) in 150 aa overlap (1-150:1-147)

               10        20        30        40        50        60
pF1KE0 MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPW
       ::.:: ..: :.  :::.:. ::.::::.  ....:.:::: . ::..:::.: ..   :
CCDS13 MEAVAKFDFTASGEDELSFHTGDVLKILS--NQEEWFKAELGSQEGYVPKNFIDIQFPKW
               10        20          30        40        50        

               70        80        90       100       110       120
pF1KE0 YSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYFL
       .   .::. ::..:: .. .: :.:: :.::::.::.:: . :.::::::.:. .:.:::
CCDS13 FHEGLSRHQAENLLMGKE-VGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNYFL
       60        70         80        90       100       110       

              130       140       150       160       170       180
pF1KE0 WEEKFNSLNELVDFYRTTTIAKKRQIFLRDEEPLLKSPGACFAQAQFDFSAQDPSQLSFR
       : ::: :::.:::.:::..:....::::::                              
CCDS13 WTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQGHRGNSLDRRSQGGPHLSGAVGEE
       120       130       140       150       160       170       




217 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 19:11:31 2016 done: Wed Nov  2 19:11:32 2016
 Total Scan time:  1.530 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]