Result of FASTA (omim) for
pF1KE0639
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0639, 214 aa
1>>>pF1KE0639 214 - 214 aa - 214 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.6321+/-0.000621; mu= -8.2782+/- 0.037
mean_var=581.6991+/-130.429, 0's: 0 Z-trim(115.8): 1834 B-trim: 0 in 0/51
Lambda= 0.053177
statistics sampled from 23978 (26459) to 23978 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.686), E-opt: 0.2 (0.31), width: 16
Scan time: 4.650
The best scores are: opt bits E(85289)
NP_001271293 (OMIM: 613472) serine/threonine-prote ( 470) 1379 121.0 3.2e-27
NP_001092906 (OMIM: 613472) serine/threonine-prote ( 472) 1379 121.0 3.2e-27
XP_016877557 (OMIM: 613472) PREDICTED: serine/thre ( 481) 1144 103.0 8.6e-22
XP_005254346 (OMIM: 613472) PREDICTED: serine/thre ( 483) 1144 103.0 8.6e-22
XP_016877560 (OMIM: 613472) PREDICTED: serine/thre ( 380) 783 75.1 1.7e-13
XP_016877561 (OMIM: 613472) PREDICTED: serine/thre ( 380) 783 75.1 1.7e-13
XP_016877558 (OMIM: 613472) PREDICTED: serine/thre ( 382) 783 75.2 1.7e-13
XP_016877559 (OMIM: 613472) PREDICTED: serine/thre ( 382) 783 75.2 1.7e-13
NP_001271294 (OMIM: 613472) serine/threonine-prote ( 355) 599 61.0 2.8e-09
XP_011537101 (OMIM: 603168) PREDICTED: serine/thre (1044) 561 58.8 3.7e-08
NP_003556 (OMIM: 603168) serine/threonine-protein (1050) 561 58.8 3.7e-08
XP_011537100 (OMIM: 603168) PREDICTED: serine/thre (1073) 561 58.8 3.8e-08
NP_055498 (OMIM: 608650) serine/threonine-protein (1036) 525 56.1 2.5e-07
NP_001136082 (OMIM: 608650) serine/threonine-prote (1036) 525 56.1 2.5e-07
NP_001230242 (OMIM: 607652) serine/threonine-prote (1294) 452 50.6 1.4e-05
XP_016859293 (OMIM: 607652) PREDICTED: serine/thre (1294) 452 50.6 1.4e-05
XP_011509261 (OMIM: 607652) PREDICTED: serine/thre (1306) 452 50.6 1.4e-05
NP_056505 (OMIM: 607652) serine/threonine-protein (1315) 452 50.6 1.4e-05
XP_005246521 (OMIM: 607652) PREDICTED: serine/thre (1315) 452 50.6 1.4e-05
NP_113605 (OMIM: 606495) MAP/microtubule affinity- ( 688) 443 49.5 1.6e-05
NP_001186796 (OMIM: 606495) MAP/microtubule affini ( 752) 443 49.5 1.7e-05
NP_009125 (OMIM: 114480,176807,259500,604373,60926 ( 543) 439 49.0 1.7e-05
XP_016884049 (OMIM: 114480,176807,259500,604373,60 ( 584) 439 49.1 1.8e-05
NP_001005735 (OMIM: 114480,176807,259500,604373,60 ( 586) 439 49.1 1.8e-05
XP_011528141 (OMIM: 114480,176807,259500,604373,60 ( 596) 439 49.1 1.8e-05
NP_001339 (OMIM: 603289) death-associated protein ( 454) 436 48.7 1.9e-05
XP_005259565 (OMIM: 603289) PREDICTED: death-assoc ( 454) 436 48.7 1.9e-05
NP_003647 (OMIM: 604998) calcium/calmodulin-depend ( 370) 429 48.0 2.4e-05
XP_005265573 (OMIM: 604998) PREDICTED: calcium/cal ( 413) 429 48.0 2.6e-05
NP_001244316 (OMIM: 114480,176807,259500,604373,60 ( 322) 425 47.6 2.8e-05
XP_011528147 (OMIM: 114480,176807,259500,604373,60 ( 322) 425 47.6 2.8e-05
XP_016884050 (OMIM: 114480,176807,259500,604373,60 ( 322) 425 47.6 2.8e-05
XP_005267700 (OMIM: 602678) PREDICTED: MAP/microtu ( 643) 430 48.4 3.1e-05
NP_001273055 (OMIM: 606511) serine/threonine-prote ( 780) 431 48.6 3.2e-05
XP_005273191 (OMIM: 606511) PREDICTED: serine/thre ( 781) 431 48.7 3.2e-05
XP_016876782 (OMIM: 602678) PREDICTED: MAP/microtu ( 708) 430 48.5 3.2e-05
XP_011507863 (OMIM: 606511) PREDICTED: serine/thre ( 788) 431 48.7 3.2e-05
NP_001122392 (OMIM: 602678) MAP/microtubule affini ( 713) 430 48.5 3.2e-05
NP_061120 (OMIM: 606511) serine/threonine-protein ( 795) 431 48.7 3.3e-05
NP_001273053 (OMIM: 606511) serine/threonine-prote ( 796) 431 48.7 3.3e-05
XP_016876781 (OMIM: 602678) PREDICTED: MAP/microtu ( 722) 430 48.5 3.3e-05
XP_016876780 (OMIM: 602678) PREDICTED: MAP/microtu ( 728) 430 48.5 3.3e-05
NP_002367 (OMIM: 602678) MAP/microtubule affinity- ( 729) 430 48.5 3.3e-05
XP_005267699 (OMIM: 602678) PREDICTED: MAP/microtu ( 737) 430 48.5 3.3e-05
XP_005267698 (OMIM: 602678) PREDICTED: MAP/microtu ( 738) 430 48.5 3.3e-05
XP_006720209 (OMIM: 602678) PREDICTED: MAP/microtu ( 739) 430 48.5 3.3e-05
NP_001122391 (OMIM: 602678) MAP/microtubule affini ( 744) 430 48.5 3.3e-05
NP_001310234 (OMIM: 603072) aurora kinase A [Homo ( 403) 424 47.6 3.3e-05
XP_016883524 (OMIM: 603072) PREDICTED: aurora kina ( 403) 424 47.6 3.3e-05
NP_001310233 (OMIM: 603072) aurora kinase A [Homo ( 403) 424 47.6 3.3e-05
>>NP_001271293 (OMIM: 613472) serine/threonine-protein k (470 aa)
initn: 1379 init1: 1379 opt: 1379 Z-score: 609.7 bits: 121.0 E(85289): 3.2e-27
Smith-Waterman score: 1379; 100.0% identity (100.0% similar) in 204 aa overlap (1-204:1-204)
10 20 30 40 50 60
pF1KE0 MAGPGWGPPRLDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAGPGWGPPRLDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 TEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYM
130 140 150 160 170 180
190 200 210
pF1KE0 APEMVCQRQYDARVDLWSMGVILYGETSFPCFSP
::::::::::::::::::::::::
NP_001 APEMVCQRQYDARVDLWSMGVILYEALFGQPPFASRSFSELEEKIRSNRVIELPLRPLLS
190 200 210 220 230 240
>>NP_001092906 (OMIM: 613472) serine/threonine-protein k (472 aa)
initn: 1379 init1: 1379 opt: 1379 Z-score: 609.7 bits: 121.0 E(85289): 3.2e-27
Smith-Waterman score: 1379; 100.0% identity (100.0% similar) in 204 aa overlap (1-204:1-204)
10 20 30 40 50 60
pF1KE0 MAGPGWGPPRLDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAGPGWGPPRLDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 TEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYM
130 140 150 160 170 180
190 200 210
pF1KE0 APEMVCQRQYDARVDLWSMGVILYGETSFPCFSP
::::::::::::::::::::::::
NP_001 APEMVCQRQYDARVDLWSMGVILYEALFGQPPFASRSFSELEEKIRSNRVIELPLRPLLS
190 200 210 220 230 240
>>XP_016877557 (OMIM: 613472) PREDICTED: serine/threonin (481 aa)
initn: 1144 init1: 1144 opt: 1144 Z-score: 512.2 bits: 103.0 E(85289): 8.6e-22
Smith-Waterman score: 1144; 97.1% identity (98.3% similar) in 175 aa overlap (30-204:41-215)
10 20 30 40 50
pF1KE0 MAGPGWGPPRLDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENL
. . :::::::::::::::::::::::::
XP_016 LEKTRLRLCREARIPESAFLTGLTRESWEARCWCAKDTREVVAIKCVAKKSLNKASVENL
20 30 40 50 60 70
60 70 80 90 100 110
pF1KE0 LTEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQ
80 90 100 110 120 130
120 130 140 150 160 170
pF1KE0 QLASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLY
140 150 160 170 180 190
180 190 200 210
pF1KE0 MAPEMVCQRQYDARVDLWSMGVILYGETSFPCFSP
:::::::::::::::::::::::::
XP_016 MAPEMVCQRQYDARVDLWSMGVILYEALFGQPPFASRSFSELEEKIRSNRVIELPLRPLL
200 210 220 230 240 250
>>XP_005254346 (OMIM: 613472) PREDICTED: serine/threonin (483 aa)
initn: 1144 init1: 1144 opt: 1144 Z-score: 512.2 bits: 103.0 E(85289): 8.6e-22
Smith-Waterman score: 1144; 97.1% identity (98.3% similar) in 175 aa overlap (30-204:41-215)
10 20 30 40 50
pF1KE0 MAGPGWGPPRLDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENL
. . :::::::::::::::::::::::::
XP_005 LEKTRLRLCREARIPESAFLTGLTRESWEARCWCAKDTREVVAIKCVAKKSLNKASVENL
20 30 40 50 60 70
60 70 80 90 100 110
pF1KE0 LTEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQ
80 90 100 110 120 130
120 130 140 150 160 170
pF1KE0 QLASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLY
140 150 160 170 180 190
180 190 200 210
pF1KE0 MAPEMVCQRQYDARVDLWSMGVILYGETSFPCFSP
:::::::::::::::::::::::::
XP_005 MAPEMVCQRQYDARVDLWSMGVILYEALFGQPPFASRSFSELEEKIRSNRVIELPLRPLL
200 210 220 230 240 250
>>XP_016877560 (OMIM: 613472) PREDICTED: serine/threonin (380 aa)
initn: 783 init1: 783 opt: 783 Z-score: 363.5 bits: 75.1 E(85289): 1.7e-13
Smith-Waterman score: 783; 100.0% identity (100.0% similar) in 114 aa overlap (91-204:1-114)
70 80 90 100 110 120
pF1KE0 TEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQ
::::::::::::::::::::::::::::::
XP_016 MEFCAGGDLSRFIHTRRILPEKVARVFMQQ
10 20 30
130 140 150 160 170 180
pF1KE0 LASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYM
40 50 60 70 80 90
190 200 210
pF1KE0 APEMVCQRQYDARVDLWSMGVILYGETSFPCFSP
::::::::::::::::::::::::
XP_016 APEMVCQRQYDARVDLWSMGVILYEALFGQPPFASRSFSELEEKIRSNRVIELPLRPLLS
100 110 120 130 140 150
>>XP_016877561 (OMIM: 613472) PREDICTED: serine/threonin (380 aa)
initn: 783 init1: 783 opt: 783 Z-score: 363.5 bits: 75.1 E(85289): 1.7e-13
Smith-Waterman score: 783; 100.0% identity (100.0% similar) in 114 aa overlap (91-204:1-114)
70 80 90 100 110 120
pF1KE0 TEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQ
::::::::::::::::::::::::::::::
XP_016 MEFCAGGDLSRFIHTRRILPEKVARVFMQQ
10 20 30
130 140 150 160 170 180
pF1KE0 LASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYM
40 50 60 70 80 90
190 200 210
pF1KE0 APEMVCQRQYDARVDLWSMGVILYGETSFPCFSP
::::::::::::::::::::::::
XP_016 APEMVCQRQYDARVDLWSMGVILYEALFGQPPFASRSFSELEEKIRSNRVIELPLRPLLS
100 110 120 130 140 150
>>XP_016877558 (OMIM: 613472) PREDICTED: serine/threonin (382 aa)
initn: 783 init1: 783 opt: 783 Z-score: 363.5 bits: 75.2 E(85289): 1.7e-13
Smith-Waterman score: 783; 100.0% identity (100.0% similar) in 114 aa overlap (91-204:1-114)
70 80 90 100 110 120
pF1KE0 TEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQ
::::::::::::::::::::::::::::::
XP_016 MEFCAGGDLSRFIHTRRILPEKVARVFMQQ
10 20 30
130 140 150 160 170 180
pF1KE0 LASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYM
40 50 60 70 80 90
190 200 210
pF1KE0 APEMVCQRQYDARVDLWSMGVILYGETSFPCFSP
::::::::::::::::::::::::
XP_016 APEMVCQRQYDARVDLWSMGVILYEALFGQPPFASRSFSELEEKIRSNRVIELPLRPLLS
100 110 120 130 140 150
>>XP_016877559 (OMIM: 613472) PREDICTED: serine/threonin (382 aa)
initn: 783 init1: 783 opt: 783 Z-score: 363.5 bits: 75.2 E(85289): 1.7e-13
Smith-Waterman score: 783; 100.0% identity (100.0% similar) in 114 aa overlap (91-204:1-114)
70 80 90 100 110 120
pF1KE0 TEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQ
::::::::::::::::::::::::::::::
XP_016 MEFCAGGDLSRFIHTRRILPEKVARVFMQQ
10 20 30
130 140 150 160 170 180
pF1KE0 LASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYM
40 50 60 70 80 90
190 200 210
pF1KE0 APEMVCQRQYDARVDLWSMGVILYGETSFPCFSP
::::::::::::::::::::::::
XP_016 APEMVCQRQYDARVDLWSMGVILYEALFGQPPFASRSFSELEEKIRSNRVIELPLRPLLS
100 110 120 130 140 150
>>NP_001271294 (OMIM: 613472) serine/threonine-protein k (355 aa)
initn: 599 init1: 599 opt: 599 Z-score: 287.5 bits: 61.0 E(85289): 2.8e-09
Smith-Waterman score: 599; 100.0% identity (100.0% similar) in 87 aa overlap (118-204:1-87)
90 100 110 120 130 140
pF1KE0 YLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLHERNISHLDLKPQNILLSS
::::::::::::::::::::::::::::::
NP_001 MQQLASALQFLHERNISHLDLKPQNILLSS
10 20 30
150 160 170 180 190 200
pF1KE0 LEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYMAPEMVCQRQYDARVDLWSMGVILYGET
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYMAPEMVCQRQYDARVDLWSMGVILYEAL
40 50 60 70 80 90
210
pF1KE0 SFPCFSP
NP_001 FGQPPFASRSFSELEEKIRSNRVIELPLRPLLSRDCRDLLQRLLERDPSRRISFQDFFAH
100 110 120 130 140 150
>>XP_011537101 (OMIM: 603168) PREDICTED: serine/threonin (1044 aa)
initn: 528 init1: 318 opt: 561 Z-score: 267.4 bits: 58.8 E(85289): 3.7e-08
Smith-Waterman score: 569; 41.8% identity (71.6% similar) in 225 aa overlap (4-214:3-226)
10 20 30 40 50
pF1KE0 MAGPGWGPPRLDG-FILTER--LGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVE
:: : . : : .... .: :..:.:.:. .. ::.::. ::.: :...
XP_011 MEPGRGGTETVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTL
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 NLLTEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVF
: ::.::: ..: .:: : ::: ....::.::.: ::::. ..:. : : : . :.:
XP_011 -LGKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLF
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 MQQLASALQFLHERNISHLDLKPQNILLSS----LEKPH---LKLADFGFAQHMSPWDEK
.::.:.:...:: ..: : ::::::::::. .:. .:.::::::....
XP_011 LQQIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRANPNSIRVKIADFGFARYLQSNMMA
120 130 140 150 160 170
180 190 200 210
pF1KE0 HVLRGSPLYMAPEMVCQRQYDARVDLWSMGVILY----GETSFPCFSP
.: :::.:::::.. ...::...::::.:.:.: :.. : ::
XP_011 ATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFYEKNKT
180 190 200 210 220 230
XP_011 LVPTIPRETSAPLRQLLLALLQRNHKDRMDFDEFFHHPFLDASPSVRKSPPVPVPSYPSS
240 250 260 270 280 290
214 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 19:19:15 2016 done: Wed Nov 2 19:19:16 2016
Total Scan time: 4.650 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]