Result of FASTA (ccds) for
pF1KE0639
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0639, 214 aa
1>>>pF1KE0639 214 - 214 aa - 214 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.9517+/-0.00112; mu= 4.6376+/- 0.065
mean_var=192.4122+/-44.715, 0's: 0 Z-trim(108.8): 687 B-trim: 338 in 1/48
Lambda= 0.092461
statistics sampled from 9622 (10429) to 9622 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.705), E-opt: 0.2 (0.32), width: 16
Scan time: 1.830
The best scores are: opt bits E(32554)
CCDS76779.1 ULK3 gene_id:25989|Hs108|chr15 ( 470) 1379 196.7 2e-50
CCDS45305.1 ULK3 gene_id:25989|Hs108|chr15 ( 472) 1379 196.7 2e-50
CCDS9274.1 ULK1 gene_id:8408|Hs108|chr12 (1050) 561 88.0 2.3e-17
CCDS11213.1 ULK2 gene_id:9706|Hs108|chr17 (1036) 525 83.2 6.5e-16
CCDS58750.1 STK36 gene_id:27148|Hs108|chr2 (1294) 452 73.6 6.4e-13
CCDS2421.1 STK36 gene_id:27148|Hs108|chr2 (1315) 452 73.6 6.4e-13
CCDS12658.1 MARK4 gene_id:57787|Hs108|chr19 ( 688) 443 72.1 9.7e-13
CCDS56097.1 MARK4 gene_id:57787|Hs108|chr19 ( 752) 443 72.1 1e-12
CCDS13843.1 CHEK2 gene_id:11200|Hs108|chr22 ( 543) 439 71.4 1.2e-12
CCDS33629.1 CHEK2 gene_id:11200|Hs108|chr22 ( 586) 439 71.4 1.3e-12
CCDS12116.1 DAPK3 gene_id:1613|Hs108|chr19 ( 454) 436 70.9 1.4e-12
CCDS2582.1 CAMK1 gene_id:8536|Hs108|chr3 ( 370) 429 69.9 2.4e-12
CCDS73034.1 MARK1 gene_id:4139|Hs108|chr1 ( 780) 431 70.5 3.2e-12
CCDS31029.2 MARK1 gene_id:4139|Hs108|chr1 ( 795) 431 70.5 3.2e-12
CCDS73033.1 MARK1 gene_id:4139|Hs108|chr1 ( 796) 431 70.5 3.2e-12
CCDS55947.1 MARK3 gene_id:4140|Hs108|chr14 ( 713) 430 70.3 3.3e-12
CCDS41993.1 MARK3 gene_id:4140|Hs108|chr14 ( 729) 430 70.4 3.4e-12
CCDS45166.1 MARK3 gene_id:4140|Hs108|chr14 ( 744) 430 70.4 3.4e-12
CCDS45165.1 MARK3 gene_id:4140|Hs108|chr14 ( 753) 430 70.4 3.4e-12
CCDS13451.1 AURKA gene_id:6790|Hs108|chr20 ( 403) 424 69.2 4e-12
CCDS53651.1 MARK2 gene_id:2011|Hs108|chr11 ( 709) 427 69.9 4.4e-12
CCDS53650.1 MARK2 gene_id:2011|Hs108|chr11 ( 719) 427 69.9 4.4e-12
CCDS8051.2 MARK2 gene_id:2011|Hs108|chr11 ( 724) 427 70.0 4.4e-12
CCDS41665.1 MARK2 gene_id:2011|Hs108|chr11 ( 745) 427 70.0 4.5e-12
CCDS53649.1 MARK2 gene_id:2011|Hs108|chr11 ( 788) 427 70.0 4.7e-12
CCDS60974.1 SIK3 gene_id:23387|Hs108|chr11 (1261) 428 70.4 5.8e-12
CCDS8379.2 SIK3 gene_id:23387|Hs108|chr11 (1321) 428 70.4 5.9e-12
CCDS1486.1 CAMK1G gene_id:57172|Hs108|chr1 ( 476) 420 68.8 6.5e-12
CCDS59401.1 PRKD2 gene_id:25865|Hs108|chr19 ( 721) 419 68.9 9.2e-12
CCDS58514.1 AURKB gene_id:9212|Hs108|chr17 ( 303) 412 67.5 1e-11
CCDS12689.1 PRKD2 gene_id:25865|Hs108|chr19 ( 878) 419 69.0 1e-11
CCDS11134.1 AURKB gene_id:9212|Hs108|chr17 ( 344) 412 67.6 1.1e-11
CCDS67162.1 AURKB gene_id:9212|Hs108|chr17 ( 345) 412 67.6 1.1e-11
CCDS7092.1 CAMK1D gene_id:57118|Hs108|chr10 ( 357) 412 67.6 1.1e-11
CCDS7091.1 CAMK1D gene_id:57118|Hs108|chr10 ( 385) 412 67.6 1.2e-11
CCDS3735.1 PLK4 gene_id:10733|Hs108|chr4 ( 970) 418 68.9 1.2e-11
CCDS46206.1 AURKC gene_id:6795|Hs108|chr19 ( 275) 409 67.1 1.3e-11
CCDS46205.1 AURKC gene_id:6795|Hs108|chr19 ( 290) 409 67.1 1.3e-11
CCDS33128.1 AURKC gene_id:6795|Hs108|chr19 ( 309) 409 67.1 1.4e-11
CCDS13610.1 HUNK gene_id:30811|Hs108|chr21 ( 714) 414 68.2 1.5e-11
CCDS1789.1 PRKD3 gene_id:23683|Hs108|chr2 ( 890) 414 68.3 1.7e-11
CCDS82645.1 LOC102724428 gene_id:102724428|Hs108|c ( 783) 412 68.0 1.9e-11
CCDS33575.1 SIK1 gene_id:150094|Hs108|chr21 ( 783) 412 68.0 1.9e-11
CCDS1453.2 NUAK2 gene_id:81788|Hs108|chr1 ( 672) 410 67.6 2e-11
CCDS31892.1 NUAK1 gene_id:9891|Hs108|chr12 ( 661) 409 67.5 2.2e-11
CCDS10188.1 DAPK2 gene_id:23604|Hs108|chr15 ( 370) 403 66.4 2.6e-11
CCDS9637.1 PRKD1 gene_id:5587|Hs108|chr14 ( 912) 408 67.5 3e-11
CCDS81796.1 PRKD1 gene_id:5587|Hs108|chr14 ( 920) 408 67.5 3e-11
CCDS43842.1 DAPK1 gene_id:1612|Hs108|chr9 (1430) 411 68.2 3e-11
CCDS12921.1 BRSK1 gene_id:84446|Hs108|chr19 ( 778) 405 67.1 3.5e-11
>>CCDS76779.1 ULK3 gene_id:25989|Hs108|chr15 (470 aa)
initn: 1379 init1: 1379 opt: 1379 Z-score: 1018.8 bits: 196.7 E(32554): 2e-50
Smith-Waterman score: 1379; 100.0% identity (100.0% similar) in 204 aa overlap (1-204:1-204)
10 20 30 40 50 60
pF1KE0 MAGPGWGPPRLDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 MAGPGWGPPRLDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 TEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 TEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 LASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYM
130 140 150 160 170 180
190 200 210
pF1KE0 APEMVCQRQYDARVDLWSMGVILYGETSFPCFSP
::::::::::::::::::::::::
CCDS76 APEMVCQRQYDARVDLWSMGVILYEALFGQPPFASRSFSELEEKIRSNRVIELPLRPLLS
190 200 210 220 230 240
>>CCDS45305.1 ULK3 gene_id:25989|Hs108|chr15 (472 aa)
initn: 1379 init1: 1379 opt: 1379 Z-score: 1018.8 bits: 196.7 E(32554): 2e-50
Smith-Waterman score: 1379; 100.0% identity (100.0% similar) in 204 aa overlap (1-204:1-204)
10 20 30 40 50 60
pF1KE0 MAGPGWGPPRLDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MAGPGWGPPRLDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 TEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 TEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 LASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYM
130 140 150 160 170 180
190 200 210
pF1KE0 APEMVCQRQYDARVDLWSMGVILYGETSFPCFSP
::::::::::::::::::::::::
CCDS45 APEMVCQRQYDARVDLWSMGVILYEALFGQPPFASRSFSELEEKIRSNRVIELPLRPLLS
190 200 210 220 230 240
>>CCDS9274.1 ULK1 gene_id:8408|Hs108|chr12 (1050 aa)
initn: 528 init1: 318 opt: 561 Z-score: 425.1 bits: 88.0 E(32554): 2.3e-17
Smith-Waterman score: 569; 41.8% identity (71.6% similar) in 225 aa overlap (4-214:3-226)
10 20 30 40 50
pF1KE0 MAGPGWGPPRLDG-FILTER--LGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVE
:: : . : : .... .: :..:.:.:. .. ::.::. ::.: :...
CCDS92 MEPGRGGTETVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTL
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 NLLTEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVF
: ::.::: ..: .:: : ::: ....::.::.: ::::. ..:. : : : . :.:
CCDS92 -LGKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLF
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 MQQLASALQFLHERNISHLDLKPQNILLSS----LEKPH---LKLADFGFAQHMSPWDEK
.::.:.:...:: ..: : ::::::::::. .:. .:.::::::....
CCDS92 LQQIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRANPNSIRVKIADFGFARYLQSNMMA
120 130 140 150 160 170
180 190 200 210
pF1KE0 HVLRGSPLYMAPEMVCQRQYDARVDLWSMGVILY----GETSFPCFSP
.: :::.:::::.. ...::...::::.:.:.: :.. : ::
CCDS92 ATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFYEKNKT
180 190 200 210 220 230
CCDS92 LVPTIPRETSAPLRQLLLALLQRNHKDRMDFDEFFHHPFLDASPSVRKSPPVPVPSYPSS
240 250 260 270 280 290
>>CCDS11213.1 ULK2 gene_id:9706|Hs108|chr17 (1036 aa)
initn: 506 init1: 284 opt: 525 Z-score: 399.2 bits: 83.2 E(32554): 6.5e-16
Smith-Waterman score: 531; 41.3% identity (71.4% similar) in 206 aa overlap (20-214:15-219)
10 20 30 40 50 60
pF1KE0 MAGPGWGPPRLDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLL
.: :..:.:... .. : :::: . ::.:.:... :
CCDS11 MEVVGDFEYSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQIL-LG
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 TEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQ
::.::: ..: .:: : : : ....:.::.: ::::. ..... : : . :::..:
CCDS11 KEIKILKELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQ
60 70 80 90 100 110
130 140 150 160 170
pF1KE0 LASALQFLHERNISHLDLKPQNILLS-------SLEKPHLKLADFGFAQHMSPWDEKHVL
.:.:...:: ..: : :::::::::: :. ..:.::::::... .:
CCDS11 IAAAMRILHSKGIIHRDLKPQNILLSYANRRKSSVSGIRIKIADFGFARYLHSNMMAATL
120 130 140 150 160 170
180 190 200 210
pF1KE0 RGSPLYMAPEMVCQRQYDARVDLWSMGVILY----GETSFPCFSP
:::.:::::.. ...:::..::::.:...: :. : ::
CCDS11 CGSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRSLMP
180 190 200 210 220 230
CCDS11 SIPRETSPYLANLLLGLLQRNQKDRMDFEAFFSHPFLEQGPVKKSCPVPVPMYSGSVSGS
240 250 260 270 280 290
>>CCDS58750.1 STK36 gene_id:27148|Hs108|chr2 (1294 aa)
initn: 409 init1: 147 opt: 452 Z-score: 345.5 bits: 73.6 E(32554): 6.4e-13
Smith-Waterman score: 452; 40.4% identity (69.7% similar) in 198 aa overlap (11-204:1-191)
10 20 30 40 50 60
pF1KE0 MAGPGWGPPRLDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLL
.. . . : .: :... :::. .: . .:::.: . : . .. ..::
CCDS58 MEKYHVLEMIGEGSFGRVYKGR-RKYSAQVVALKFIPKLGRSEKELRNLQ
10 20 30 40
70 80 90 100 110
pF1KE0 TEIEILKGIRHPHIVQLKD-FQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQ
::::..:.:::.::.. : :. :.. . .. .. : :.: .... ::: ....
CCDS58 REIEIMRGLRHPNIVHMLDSFETDKE-VVVVTDY-AEGELFQILEDDGKLPEDQVQAIAA
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE0 QLASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVL---RGS
::.::: .:: . : : :.:::::::. . .:: :::::. :: . :: .:.
CCDS58 QLVSALYYLHSHRILHRDMKPQNILLA--KGGGIKLCDFGFARAMS--TNTMVLTSIKGT
110 120 130 140 150 160
180 190 200 210
pF1KE0 PLYMAPEMVCQRQYDARVDLWSMGVILYGETSFPCFSP
::::.::.: .: :: .::::.: :::
CCDS58 PLYMSPELVEERPYDHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTI
170 180 190 200 210 220
>>CCDS2421.1 STK36 gene_id:27148|Hs108|chr2 (1315 aa)
initn: 409 init1: 147 opt: 452 Z-score: 345.4 bits: 73.6 E(32554): 6.4e-13
Smith-Waterman score: 452; 40.4% identity (69.7% similar) in 198 aa overlap (11-204:1-191)
10 20 30 40 50 60
pF1KE0 MAGPGWGPPRLDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLL
.. . . : .: :... :::. .: . .:::.: . : . .. ..::
CCDS24 MEKYHVLEMIGEGSFGRVYKGR-RKYSAQVVALKFIPKLGRSEKELRNLQ
10 20 30 40
70 80 90 100 110
pF1KE0 TEIEILKGIRHPHIVQLKD-FQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQ
::::..:.:::.::.. : :. :.. . .. .. : :.: .... ::: ....
CCDS24 REIEIMRGLRHPNIVHMLDSFETDKE-VVVVTDY-AEGELFQILEDDGKLPEDQVQAIAA
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE0 QLASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVL---RGS
::.::: .:: . : : :.:::::::. . .:: :::::. :: . :: .:.
CCDS24 QLVSALYYLHSHRILHRDMKPQNILLA--KGGGIKLCDFGFARAMS--TNTMVLTSIKGT
110 120 130 140 150 160
180 190 200 210
pF1KE0 PLYMAPEMVCQRQYDARVDLWSMGVILYGETSFPCFSP
::::.::.: .: :: .::::.: :::
CCDS24 PLYMSPELVEERPYDHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTI
170 180 190 200 210 220
>>CCDS12658.1 MARK4 gene_id:57787|Hs108|chr19 (688 aa)
initn: 408 init1: 264 opt: 443 Z-score: 342.2 bits: 72.1 E(32554): 9.7e-13
Smith-Waterman score: 443; 37.1% identity (72.6% similar) in 197 aa overlap (9-204:54-247)
10 20 30
pF1KE0 MAGPGWGPPRLDGFILTERLGSGTYATVYKAYAKKDTR
:.. .. : . .:.:..: : : :
CCDS12 GRSSDKGPSWSSRSLGARCRNSIASCPEEQPHVGNYRLLRTIGKGNFAKVKLARHILTGR
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE0 EVVAIKCVAKKSLNKASVENLLTEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGD
:: ::: . : .:: .:...:. :..:.::. ::.::.: . ..::.::. ..:.
CCDS12 EV-AIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGE
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE0 LSRFIHTRRILPEKVARVFMQQLASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADF
. .. .. . :: ::. ..:..::... :..:: : ::: .:.::.. . ..:.:::
CCDS12 VFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDA--EANIKIADF
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE0 GFAQHMSPWDEKHVLRGSPLYMAPEMVCQRQYDA-RVDLWSMGVILYGETSFPCFSP
::..... .. .. ::: : :::. ..::. .::.::.:::::
CCDS12 GFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHN
210 220 230 240 250 260
CCDS12 LKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKDKWINIGYEGEELK
270 280 290 300 310 320
>>CCDS56097.1 MARK4 gene_id:57787|Hs108|chr19 (752 aa)
initn: 408 init1: 264 opt: 443 Z-score: 341.7 bits: 72.1 E(32554): 1e-12
Smith-Waterman score: 443; 37.1% identity (72.6% similar) in 197 aa overlap (9-204:54-247)
10 20 30
pF1KE0 MAGPGWGPPRLDGFILTERLGSGTYATVYKAYAKKDTR
:.. .. : . .:.:..: : : :
CCDS56 GRSSDKGPSWSSRSLGARCRNSIASCPEEQPHVGNYRLLRTIGKGNFAKVKLARHILTGR
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE0 EVVAIKCVAKKSLNKASVENLLTEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGD
:: ::: . : .:: .:...:. :..:.::. ::.::.: . ..::.::. ..:.
CCDS56 EV-AIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGE
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE0 LSRFIHTRRILPEKVARVFMQQLASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADF
. .. .. . :: ::. ..:..::... :..:: : ::: .:.::.. . ..:.:::
CCDS56 VFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDA--EANIKIADF
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE0 GFAQHMSPWDEKHVLRGSPLYMAPEMVCQRQYDA-RVDLWSMGVILYGETSFPCFSP
::..... .. .. ::: : :::. ..::. .::.::.:::::
CCDS56 GFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHN
210 220 230 240 250 260
CCDS56 LKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKDKWINIGYEGEELK
270 280 290 300 310 320
>>CCDS13843.1 CHEK2 gene_id:11200|Hs108|chr22 (543 aa)
initn: 333 init1: 156 opt: 439 Z-score: 340.5 bits: 71.4 E(32554): 1.2e-12
Smith-Waterman score: 439; 37.9% identity (68.7% similar) in 214 aa overlap (12-213:218-428)
10 20 30 40
pF1KE0 MAGPGWGPPRLDGFILTERLGSGTYATVYKAYAKKDTREVV
: .:... ::::. . : :. .: ..:
CCDS13 EIALSLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKV-
190 200 210 220 230 240
50 60 70 80 90
pF1KE0 AIKCVAKKSLNKASVE------NLLTEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCA
::: ..:... .:.. :. ::::::: . :: :...:.: .:... :...:.
CCDS13 AIKIISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNF-FDAEDYYIVLELME
250 260 270 280 290 300
100 110 120 130 140 150
pF1KE0 GGDL-SRFIHTRRILPEKVARVFMQQLASALQFLHERNISHLDLKPQNILLSSLEKPHL-
::.: .. . ..: : : . .... :. :.:.::: .: : ::::.:.:::: :. :
CCDS13 GGELFDKVVGNKR-LKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLI
310 320 330 340 350 360
160 170 180 190 200
pF1KE0 KLADFGFAQHMSPWDEKHVLRGSPLYMAPEM---VCQRQYDARVDLWSMGVILYGETS-F
:..::: .. .. . ..: :.: :.:::. : :. :: ::.::::. : .
CCDS13 KITDFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGY
370 380 390 400 410 420
210
pF1KE0 PCFSP
: ::
CCDS13 PPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHP
430 440 450 460 470 480
>>CCDS33629.1 CHEK2 gene_id:11200|Hs108|chr22 (586 aa)
initn: 333 init1: 156 opt: 439 Z-score: 340.1 bits: 71.4 E(32554): 1.3e-12
Smith-Waterman score: 439; 37.9% identity (68.7% similar) in 214 aa overlap (12-213:261-471)
10 20 30 40
pF1KE0 MAGPGWGPPRLDGFILTERLGSGTYATVYKAYAKKDTREVV
: .:... ::::. . : :. .: ..:
CCDS33 EIALSLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKV-
240 250 260 270 280
50 60 70 80 90
pF1KE0 AIKCVAKKSLNKASVE------NLLTEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCA
::: ..:... .:.. :. ::::::: . :: :...:.: .:... :...:.
CCDS33 AIKIISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNF-FDAEDYYIVLELME
290 300 310 320 330 340
100 110 120 130 140 150
pF1KE0 GGDL-SRFIHTRRILPEKVARVFMQQLASALQFLHERNISHLDLKPQNILLSSLEKPHL-
::.: .. . ..: : : . .... :. :.:.::: .: : ::::.:.:::: :. :
CCDS33 GGELFDKVVGNKR-LKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLI
350 360 370 380 390 400
160 170 180 190 200
pF1KE0 KLADFGFAQHMSPWDEKHVLRGSPLYMAPEM---VCQRQYDARVDLWSMGVILYGETS-F
:..::: .. .. . ..: :.: :.:::. : :. :: ::.::::. : .
CCDS33 KITDFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGY
410 420 430 440 450 460
210
pF1KE0 PCFSP
: ::
CCDS33 PPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHP
470 480 490 500 510 520
214 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 19:19:14 2016 done: Wed Nov 2 19:19:14 2016
Total Scan time: 1.830 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]