Result of FASTA (omim) for
pF1KE0596
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0596, 156 aa
1>>>pF1KE0596 156 - 156 aa - 156 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.2765+/-0.000269; mu= 18.3582+/- 0.017
mean_var=64.6311+/-13.066, 0's: 0 Z-trim(120.0): 34 B-trim: 0 in 0/53
Lambda= 0.159534
statistics sampled from 34616 (34658) to 34616 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.77), E-opt: 0.2 (0.406), width: 16
Scan time: 5.590
The best scores are: opt bits E(85289)
NP_004149 (OMIM: 602921) persephin preproprotein [ ( 156) 1099 260.5 8.2e-70
NP_476432 (OMIM: 603886) artemin isoform 1 preprop ( 220) 319 81.1 1.1e-15
NP_476431 (OMIM: 603886) artemin isoform 3 [Homo s ( 228) 319 81.1 1.2e-15
NP_001129687 (OMIM: 603886) artemin isoform 3 [Hom ( 228) 319 81.1 1.2e-15
XP_011526343 (OMIM: 602018) PREDICTED: neurturin i ( 197) 298 76.2 3e-14
NP_004549 (OMIM: 602018) neurturin preproprotein [ ( 197) 298 76.2 3e-14
NP_001265027 (OMIM: 171300,209880,600837,613711) g ( 159) 230 60.5 1.3e-09
XP_011512332 (OMIM: 171300,209880,600837,613711) P ( 159) 230 60.5 1.3e-09
XP_016864826 (OMIM: 171300,209880,600837,613711) P ( 185) 230 60.5 1.5e-09
NP_954701 (OMIM: 171300,209880,600837,613711) glia ( 185) 230 60.5 1.5e-09
NP_001177398 (OMIM: 171300,209880,600837,613711) g ( 202) 230 60.6 1.6e-09
NP_000505 (OMIM: 171300,209880,600837,613711) glia ( 211) 230 60.6 1.6e-09
NP_001177397 (OMIM: 171300,209880,600837,613711) g ( 228) 230 60.6 1.7e-09
NP_005802 (OMIM: 603936) growth/differentiation fa ( 407) 140 40.2 0.0044
XP_006719257 (OMIM: 603936) PREDICTED: growth/diff ( 407) 140 40.2 0.0044
NP_000470 (OMIM: 261550,600957) muellerian-inhibit ( 560) 140 40.3 0.0054
>>NP_004149 (OMIM: 602921) persephin preproprotein [Homo (156 aa)
initn: 1099 init1: 1099 opt: 1099 Z-score: 1374.4 bits: 260.5 E(85289): 8.2e-70
Smith-Waterman score: 1099; 100.0% identity (100.0% similar) in 156 aa overlap (1-156:1-156)
10 20 30 40 50 60
pF1KE0 MAVGKFLLGSLLLLSLQLGQGWGPDARGVPVADGEFSSEQVAKAGGTWLGTHRPLARLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAVGKFLLGSLLLLSLQLGQGWGPDARGVPVADGEFSSEQVAKAGGTWLGTHRPLARLRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 ALSGPCQLWSLTLSVAELGLGYASEEKVIFRYCAGSCPRGARTQHGLALARLQGQGRAHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ALSGPCQLWSLTLSVAELGLGYASEEKVIFRYCAGSCPRGARTQHGLALARLQGQGRAHG
70 80 90 100 110 120
130 140 150
pF1KE0 GPCCRPTRYTDVAFLDDRHRWQRLPQLSAAACGCGG
::::::::::::::::::::::::::::::::::::
NP_004 GPCCRPTRYTDVAFLDDRHRWQRLPQLSAAACGCGG
130 140 150
>>NP_476432 (OMIM: 603886) artemin isoform 1 preproprote (220 aa)
initn: 327 init1: 162 opt: 319 Z-score: 402.3 bits: 81.1 E(85289): 1.1e-15
Smith-Waterman score: 319; 45.6% identity (60.8% similar) in 125 aa overlap (40-156:104-220)
10 20 30 40 50 60
pF1KE0 SLLLLSLQLGQGWGPDARGVPVADGEFSSEQVAKAGGTWLGTHRPLARLRRALSGPCQLW
..:.::: : .: : : . :.:
NP_476 CSGRARRPPPQPSRPAPPPPAPPSALPRGGRAARAGG-------PGSRARAAGARGCRLR
80 90 100 110 120
70 80 90 100 110 120
pF1KE0 SLTLSVAELGLGYASEEKVIFRYCAGSCPRGARTQHGLALARLQGQG--RAHGG------
: . : ::::. :.: : ::.:.::: : ::. : :.:: : : : : :
NP_476 SQLVPVRALGLGHRSDELVRFRFCSGSC-RRARSPHDLSLASLLGAGALRPPPGSRPVSQ
130 140 150 160 170 180
130 140 150
pF1KE0 PCCRPTRYTDVAFLDDRHRWQRLPQLSAAACGCGG
:::::::: :.:.: :. . .:::.:::: :
NP_476 PCCRPTRYEAVSFMDVNSTWRTVDRLSATACGCLG
190 200 210 220
>>NP_476431 (OMIM: 603886) artemin isoform 3 [Homo sapie (228 aa)
initn: 307 init1: 162 opt: 319 Z-score: 402.1 bits: 81.1 E(85289): 1.2e-15
Smith-Waterman score: 319; 45.6% identity (60.8% similar) in 125 aa overlap (40-156:112-228)
10 20 30 40 50 60
pF1KE0 SLLLLSLQLGQGWGPDARGVPVADGEFSSEQVAKAGGTWLGTHRPLARLRRALSGPCQLW
..:.::: : .: : : . :.:
NP_476 CSGRARRPPPQPSRPAPPPPAPPSALPRGGRAARAGG-------PGSRARAAGARGCRLR
90 100 110 120 130
70 80 90 100 110 120
pF1KE0 SLTLSVAELGLGYASEEKVIFRYCAGSCPRGARTQHGLALARLQGQG--RAHGG------
: . : ::::. :.: : ::.:.::: : ::. : :.:: : : : : :
NP_476 SQLVPVRALGLGHRSDELVRFRFCSGSC-RRARSPHDLSLASLLGAGALRPPPGSRPVSQ
140 150 160 170 180 190
130 140 150
pF1KE0 PCCRPTRYTDVAFLDDRHRWQRLPQLSAAACGCGG
:::::::: :.:.: :. . .:::.:::: :
NP_476 PCCRPTRYEAVSFMDVNSTWRTVDRLSATACGCLG
200 210 220
>>NP_001129687 (OMIM: 603886) artemin isoform 3 [Homo sa (228 aa)
initn: 307 init1: 162 opt: 319 Z-score: 402.1 bits: 81.1 E(85289): 1.2e-15
Smith-Waterman score: 319; 45.6% identity (60.8% similar) in 125 aa overlap (40-156:112-228)
10 20 30 40 50 60
pF1KE0 SLLLLSLQLGQGWGPDARGVPVADGEFSSEQVAKAGGTWLGTHRPLARLRRALSGPCQLW
..:.::: : .: : : . :.:
NP_001 CSGRARRPPPQPSRPAPPPPAPPSALPRGGRAARAGG-------PGSRARAAGARGCRLR
90 100 110 120 130
70 80 90 100 110 120
pF1KE0 SLTLSVAELGLGYASEEKVIFRYCAGSCPRGARTQHGLALARLQGQG--RAHGG------
: . : ::::. :.: : ::.:.::: : ::. : :.:: : : : : :
NP_001 SQLVPVRALGLGHRSDELVRFRFCSGSC-RRARSPHDLSLASLLGAGALRPPPGSRPVSQ
140 150 160 170 180 190
130 140 150
pF1KE0 PCCRPTRYTDVAFLDDRHRWQRLPQLSAAACGCGG
:::::::: :.:.: :. . .:::.:::: :
NP_001 PCCRPTRYEAVSFMDVNSTWRTVDRLSATACGCLG
200 210 220
>>XP_011526343 (OMIM: 602018) PREDICTED: neurturin isofo (197 aa)
initn: 323 init1: 168 opt: 298 Z-score: 376.8 bits: 76.2 E(85289): 3e-14
Smith-Waterman score: 298; 46.8% identity (68.5% similar) in 111 aa overlap (50-154:88-196)
20 30 40 50 60 70
pF1KE0 QGWGPDARGVPVADGEFSSEQVAKAGGTWLGTHRPLARLRRALSGPCQLWSLTLSVAELG
: .: :: : . . :: : : . :.:::
XP_011 RALLQGAPDAMELRELTPWAGRPPGPRRRAGPRRRRARARLG-ARPCGLRELEVRVSELG
60 70 80 90 100 110
80 90 100 110 120 130
pF1KE0 LGYASEEKVIFRYCAGSCPRGARTQHGLALARLQGQGR-----AHGGPCCRPTRYTD-VA
:::::.: :.::::::.: .::. . :.: ::. . : ... :::::: : : :.
XP_011 LGYASDETVLFRYCAGACEAAARV-YDLGLRRLRQRRRLRRERVRAQPCCRPTAYEDEVS
120 130 140 150 160 170
140 150
pF1KE0 FLDDRHRWQRLPQLSAAACGCGG
::: . :.. . .::: :.:
XP_011 FLDAHSRYHTVHELSARECACV
180 190
>>NP_004549 (OMIM: 602018) neurturin preproprotein [Homo (197 aa)
initn: 323 init1: 168 opt: 298 Z-score: 376.8 bits: 76.2 E(85289): 3e-14
Smith-Waterman score: 298; 46.8% identity (68.5% similar) in 111 aa overlap (50-154:88-196)
20 30 40 50 60 70
pF1KE0 QGWGPDARGVPVADGEFSSEQVAKAGGTWLGTHRPLARLRRALSGPCQLWSLTLSVAELG
: .: :: : . . :: : : . :.:::
NP_004 RALLQGAPDAMELRELTPWAGRPPGPRRRAGPRRRRARARLG-ARPCGLRELEVRVSELG
60 70 80 90 100 110
80 90 100 110 120 130
pF1KE0 LGYASEEKVIFRYCAGSCPRGARTQHGLALARLQGQGR-----AHGGPCCRPTRYTD-VA
:::::.: :.::::::.: .::. . :.: ::. . : ... :::::: : : :.
NP_004 LGYASDETVLFRYCAGACEAAARV-YDLGLRRLRQRRRLRRERVRAQPCCRPTAYEDEVS
120 130 140 150 160 170
140 150
pF1KE0 FLDDRHRWQRLPQLSAAACGCGG
::: . :.. . .::: :.:
NP_004 FLDAHSRYHTVHELSARECACV
180 190
>>NP_001265027 (OMIM: 171300,209880,600837,613711) glial (159 aa)
initn: 234 init1: 138 opt: 230 Z-score: 293.3 bits: 60.5 E(85289): 1.3e-09
Smith-Waterman score: 230; 39.8% identity (63.1% similar) in 103 aa overlap (57-154:57-158)
30 40 50 60 70 80
pF1KE0 RGVPVADGEFSSEQVAKAGGTWLGTHRPLARLRRALSGPCQLWSLTLSVAELGLGYASEE
: .:. . : : .. :.:..::::: ..:
NP_001 PDKQMAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKE
30 40 50 60 70 80
90 100 110 120 130 140
pF1KE0 KVIFRYCAGSCPRGARTQHGLALARLQGQGR----AHGGPCCRPTRYTD-VAFLDDRHRW
..:::::.::: .:.: . : :. . : : :::: . : ..:::: .
NP_001 ELIFRYCSGSCD-AAETTYDKILKNLSRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVY
90 100 110 120 130 140
150
pF1KE0 QRLPQLSAAACGCGG
. : . :: :::
NP_001 HILRKHSAKRCGCI
150
>>XP_011512332 (OMIM: 171300,209880,600837,613711) PREDI (159 aa)
initn: 234 init1: 138 opt: 230 Z-score: 293.3 bits: 60.5 E(85289): 1.3e-09
Smith-Waterman score: 230; 39.8% identity (63.1% similar) in 103 aa overlap (57-154:57-158)
30 40 50 60 70 80
pF1KE0 RGVPVADGEFSSEQVAKAGGTWLGTHRPLARLRRALSGPCQLWSLTLSVAELGLGYASEE
: .:. . : : .. :.:..::::: ..:
XP_011 PDKQMAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKE
30 40 50 60 70 80
90 100 110 120 130 140
pF1KE0 KVIFRYCAGSCPRGARTQHGLALARLQGQGR----AHGGPCCRPTRYTD-VAFLDDRHRW
..:::::.::: .:.: . : :. . : : :::: . : ..:::: .
XP_011 ELIFRYCSGSCD-AAETTYDKILKNLSRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVY
90 100 110 120 130 140
150
pF1KE0 QRLPQLSAAACGCGG
. : . :: :::
XP_011 HILRKHSAKRCGCI
150
>>XP_016864826 (OMIM: 171300,209880,600837,613711) PREDI (185 aa)
initn: 234 init1: 138 opt: 230 Z-score: 292.5 bits: 60.5 E(85289): 1.5e-09
Smith-Waterman score: 230; 39.8% identity (63.1% similar) in 103 aa overlap (57-154:83-184)
30 40 50 60 70 80
pF1KE0 RGVPVADGEFSSEQVAKAGGTWLGTHRPLARLRRALSGPCQLWSLTLSVAELGLGYASEE
: .:. . : : .. :.:..::::: ..:
XP_016 PDKQMAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKE
60 70 80 90 100 110
90 100 110 120 130 140
pF1KE0 KVIFRYCAGSCPRGARTQHGLALARLQGQGR----AHGGPCCRPTRYTD-VAFLDDRHRW
..:::::.::: .:.: . : :. . : : :::: . : ..:::: .
XP_016 ELIFRYCSGSCD-AAETTYDKILKNLSRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVY
120 130 140 150 160 170
150
pF1KE0 QRLPQLSAAACGCGG
. : . :: :::
XP_016 HILRKHSAKRCGCI
180
>>NP_954701 (OMIM: 171300,209880,600837,613711) glial ce (185 aa)
initn: 234 init1: 138 opt: 230 Z-score: 292.5 bits: 60.5 E(85289): 1.5e-09
Smith-Waterman score: 230; 39.8% identity (63.1% similar) in 103 aa overlap (57-154:83-184)
30 40 50 60 70 80
pF1KE0 RGVPVADGEFSSEQVAKAGGTWLGTHRPLARLRRALSGPCQLWSLTLSVAELGLGYASEE
: .:. . : : .. :.:..::::: ..:
NP_954 PDKQMAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKE
60 70 80 90 100 110
90 100 110 120 130 140
pF1KE0 KVIFRYCAGSCPRGARTQHGLALARLQGQGR----AHGGPCCRPTRYTD-VAFLDDRHRW
..:::::.::: .:.: . : :. . : : :::: . : ..:::: .
NP_954 ELIFRYCSGSCD-AAETTYDKILKNLSRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVY
120 130 140 150 160 170
150
pF1KE0 QRLPQLSAAACGCGG
. : . :: :::
NP_954 HILRKHSAKRCGCI
180
156 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 20:36:08 2016 done: Wed Nov 2 20:36:09 2016
Total Scan time: 5.590 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]