Result of FASTA (omim) for
pF1KE0578
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0578, 207 aa
1>>>pF1KE0578 207 - 207 aa - 207 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.3461+/-0.000324; mu= 19.0107+/- 0.020
mean_var=62.1560+/-12.676, 0's: 0 Z-trim(115.8): 83 B-trim: 801 in 1/49
Lambda= 0.162680
statistics sampled from 26405 (26490) to 26405 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.311), width: 16
Scan time: 6.250
The best scores are: opt bits E(85289)
NP_003859 (OMIM: 300827,309630) fibroblast growth ( 207) 1420 341.3 6.7e-94
NP_002001 (OMIM: 600921,612961) fibroblast growth ( 208) 992 240.8 1.2e-63
NP_062825 (OMIM: 605558,615721) fibroblast growth ( 211) 920 223.9 1.4e-58
XP_011533298 (OMIM: 600921,612961) PREDICTED: fibr ( 158) 666 164.2 1e-40
XP_005248321 (OMIM: 149730,180920,602115) PREDICTE ( 208) 413 104.9 9.5e-23
NP_004456 (OMIM: 149730,180920,602115) fibroblast ( 208) 413 104.9 9.5e-23
NP_065688 (OMIM: 605831) fibroblast growth factor ( 170) 403 102.5 4.2e-22
NP_001308876 (OMIM: 601515,609307) fibroblast grow ( 200) 401 102.1 6.5e-22
NP_001308877 (OMIM: 601515,609307) fibroblast grow ( 213) 401 102.1 6.8e-22
NP_001308874 (OMIM: 601515,609307) fibroblast grow ( 213) 401 102.1 6.8e-22
NP_787125 (OMIM: 601515,609307) fibroblast growth ( 252) 401 102.2 7.6e-22
NP_004106 (OMIM: 601515,609307) fibroblast growth ( 247) 398 101.5 1.2e-21
NP_004455 (OMIM: 165190,190330) fibroblast growth ( 268) 398 101.5 1.3e-21
NP_001308869 (OMIM: 601515,609307) fibroblast grow ( 187) 395 100.7 1.6e-21
NP_001308862 (OMIM: 601515,609307) fibroblast grow ( 187) 395 100.7 1.6e-21
NP_001308867 (OMIM: 601515,609307) fibroblast grow ( 187) 395 100.7 1.6e-21
NP_001308873 (OMIM: 601515,609307) fibroblast grow ( 184) 390 99.5 3.7e-21
NP_001308865 (OMIM: 601515,609307) fibroblast grow ( 184) 390 99.5 3.7e-21
NP_001308861 (OMIM: 601515,609307) fibroblast grow ( 184) 390 99.5 3.7e-21
NP_001308870 (OMIM: 601515,609307) fibroblast grow ( 185) 390 99.5 3.7e-21
NP_002000 (OMIM: 148180) fibroblast growth factor ( 194) 380 97.2 1.9e-20
NP_001132970 (OMIM: 300070) fibroblast growth fact ( 199) 377 96.5 3.2e-20
NP_001132973 (OMIM: 300070) fibroblast growth fact ( 226) 376 96.3 4.1e-20
NP_001132974 (OMIM: 300070) fibroblast growth fact ( 226) 376 96.3 4.1e-20
NP_378668 (OMIM: 300070) fibroblast growth factor ( 192) 375 96.0 4.3e-20
NP_004105 (OMIM: 300070) fibroblast growth factor ( 245) 376 96.3 4.4e-20
XP_005262456 (OMIM: 300070) PREDICTED: fibroblast ( 255) 376 96.3 4.5e-20
NP_001132972 (OMIM: 300070) fibroblast growth fact ( 255) 376 96.3 4.5e-20
XP_005247284 (OMIM: 601513,617166) PREDICTED: fibr ( 207) 375 96.0 4.6e-20
XP_006713601 (OMIM: 601513,617166) PREDICTED: fibr ( 178) 369 94.5 1.1e-19
NP_004104 (OMIM: 601513,617166) fibroblast growth ( 181) 369 94.6 1.1e-19
NP_066360 (OMIM: 601513,617166) fibroblast growth ( 243) 369 94.7 1.4e-19
NP_001290389 (OMIM: 601514) fibroblast growth fact ( 166) 349 89.8 2.7e-18
NP_004103 (OMIM: 601514) fibroblast growth factor ( 225) 350 90.2 2.8e-18
NP_066276 (OMIM: 134921) fibroblast growth factor ( 208) 347 89.4 4.4e-18
NP_001998 (OMIM: 164980) fibroblast growth factor ( 206) 329 85.2 8.1e-17
NP_001244137 (OMIM: 131220) fibroblast growth fact ( 155) 327 84.6 9.1e-17
NP_000791 (OMIM: 131220) fibroblast growth factor ( 155) 327 84.6 9.1e-17
NP_001244139 (OMIM: 131220) fibroblast growth fact ( 155) 327 84.6 9.1e-17
NP_001244138 (OMIM: 131220) fibroblast growth fact ( 155) 327 84.6 9.1e-17
NP_001244136 (OMIM: 131220) fibroblast growth fact ( 155) 327 84.6 9.1e-17
NP_001138364 (OMIM: 131220) fibroblast growth fact ( 155) 327 84.6 9.1e-17
NP_001138406 (OMIM: 131220) fibroblast growth fact ( 155) 327 84.6 9.1e-17
NP_001244134 (OMIM: 131220) fibroblast growth fact ( 155) 327 84.6 9.1e-17
NP_001138407 (OMIM: 131220) fibroblast growth fact ( 155) 327 84.6 9.1e-17
XP_016861368 (OMIM: 601513,617166) PREDICTED: fibr ( 157) 325 84.2 1.3e-16
NP_005238 (OMIM: 164950,610706) fibroblast growth ( 239) 324 84.1 2e-16
NP_001308860 (OMIM: 601515,609307) fibroblast grow ( 163) 319 82.8 3.5e-16
NP_001308878 (OMIM: 601515,609307) fibroblast grow ( 163) 319 82.8 3.5e-16
NP_001308872 (OMIM: 601515,609307) fibroblast grow ( 163) 319 82.8 3.5e-16
>>NP_003859 (OMIM: 300827,309630) fibroblast growth fact (207 aa)
initn: 1420 init1: 1420 opt: 1420 Z-score: 1806.7 bits: 341.3 E(85289): 6.7e-94
Smith-Waterman score: 1420; 100.0% identity (100.0% similar) in 207 aa overlap (1-207:1-207)
10 20 30 40 50 60
pF1KE0 MAEVGGVFASLDWDLHGFSSSLGNVPLADSPGFLNERLGQIEGKLQRGSPTDFAHLKGIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MAEVGGVFASLDWDLHGFSSSLGNVPLADSPGFLNERLGQIEGKLQRGSPTDFAHLKGIL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 RRRQLYCRTGFHLEIFPNGTVHGTRHDHSRFGILEFISLAVGLISIRGVDSGLYLGMNER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RRRQLYCRTGFHLEIFPNGTVHGTRHDHSRFGILEFISLAVGLISIRGVDSGLYLGMNER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 GELYGSKKLTRECVFREQFEENWYNTYASTLYKHSDSERQYYVALNKDGSPREGYRTKRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GELYGSKKLTRECVFREQFEENWYNTYASTLYKHSDSERQYYVALNKDGSPREGYRTKRH
130 140 150 160 170 180
190 200
pF1KE0 QKFTHFLPRPVDPSKLPSMSRDLFHYR
:::::::::::::::::::::::::::
NP_003 QKFTHFLPRPVDPSKLPSMSRDLFHYR
190 200
>>NP_002001 (OMIM: 600921,612961) fibroblast growth fact (208 aa)
initn: 969 init1: 915 opt: 992 Z-score: 1263.8 bits: 240.8 E(85289): 1.2e-63
Smith-Waterman score: 992; 71.6% identity (87.0% similar) in 208 aa overlap (1-204:4-205)
10 20 30 40 50
pF1KE0 MAEVGGVFASLDWDLHGFSSSLGNVPL--ADSPGFLNERLGQIE-GKLQRGSP-TDF
..:::. :. : . .::::. .::: .:...::: : : : :: ::.
NP_002 MAPLGEVGNYFGVQD------AVPFGNVPVLPVDSPVLLSDHLGQSEAGGLPRGPAVTDL
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 AHLKGILRRRQLYCRTGFHLEIFPNGTVHGTRHDHSRFGILEFISLAVGLISIRGVDSGL
::::::::::::::::::::::::::..:::.::::::::::::.::::.:::::::::
NP_002 DHLKGILRRRQLYCRTGFHLEIFPNGTIQGTRKDHSRFGILEFISIAVGLVSIRGVDSGL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 YLGMNERGELYGSKKLTRECVFREQFEENWYNTYASTLYKHSDSERQYYVALNKDGSPRE
::::::.::::::.:::.::::::::::::::::.:.:::: :. :.:::::::::.:::
NP_002 YLGMNEKGELYGSEKLTQECVFREQFEENWYNTYSSNLYKHVDTGRRYYVALNKDGTPRE
120 130 140 150 160 170
180 190 200
pF1KE0 GYRTKRHQKFTHFLPRPVDPSKLPSMSRDLFHYR
: ::::::::::::::::::.:.: . .:..
NP_002 GTRTKRHQKFTHFLPRPVDPDKVPELYKDILSQS
180 190 200
>>NP_062825 (OMIM: 605558,615721) fibroblast growth fact (211 aa)
initn: 908 init1: 861 opt: 920 Z-score: 1172.4 bits: 223.9 E(85289): 1.4e-58
Smith-Waterman score: 920; 63.9% identity (86.1% similar) in 208 aa overlap (1-206:4-210)
10 20 30 40 50
pF1KE0 MAEVGGVFASLDWDLHGFSSSLGNVPLADSPGFLNERLGQIEGKLQRGSP--TDFAH
.::::: ...:. . .: . : .. : .:.:: . : . ::.: ...::
NP_062 MAPLAEVGGFLGGLEGLGQQVGSHFLLPPAGERPPLLGERRSAAE-RSARGGPGAAQLAH
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LKGILRRRQLYCRTGFHLEIFPNGTVHGTRHDHSRFGILEFISLAVGLISIRGVDSGLYL
:.::::::::::::::::.:.:.:.:.:::.::: ::::::::.::::.:::::::::::
NP_062 LHGILRRRQLYCRTGFHLQILPDGSVQGTRQDHSLFGILEFISVAVGLVSIRGVDSGLYL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 GMNERGELYGSKKLTRECVFREQFEENWYNTYASTLYKHSDSERQYYVALNKDGSPREGY
:::..::::::.::: ::.:::::::::::::.:..:::.:. :.:.:::::::.::.:
NP_062 GMNDKGELYGSEKLTSECIFREQFEENWYNTYSSNIYKHGDTGRRYFVALNKDGTPRDGA
120 130 140 150 160 170
180 190 200
pF1KE0 RTKRHQKFTHFLPRPVDPSKLPSMSRDLFHYR
:.:::::::::::::::: ..: . .::. :
NP_062 RSKRHQKFTHFLPRPVDPERVPELYKDLLMYT
180 190 200 210
>>XP_011533298 (OMIM: 600921,612961) PREDICTED: fibrobla (158 aa)
initn: 655 init1: 655 opt: 666 Z-score: 851.9 bits: 164.2 E(85289): 1e-40
Smith-Waterman score: 666; 73.7% identity (88.0% similar) in 133 aa overlap (77-204:23-155)
50 60 70 80 90 100
pF1KE0 RGSPTDFAHLKGILRRRQLYCRTGFHLEIFPNG---TVHGTRHDHS--RFGILEFISLAV
: : .. : : :: .:::::::.::
XP_011 MRTAAGYSGSIETVKQKARPLTPRGQRKVLSGKWHLHSLDALGILEFISIAV
10 20 30 40 50
110 120 130 140 150 160
pF1KE0 GLISIRGVDSGLYLGMNERGELYGSKKLTRECVFREQFEENWYNTYASTLYKHSDSERQY
::.:::::::::::::::.::::::.:::.::::::::::::::::.:.:::: :. :.:
XP_011 GLVSIRGVDSGLYLGMNEKGELYGSEKLTQECVFREQFEENWYNTYSSNLYKHVDTGRRY
60 70 80 90 100 110
170 180 190 200
pF1KE0 YVALNKDGSPREGYRTKRHQKFTHFLPRPVDPSKLPSMSRDLFHYR
::::::::.:::: ::::::::::::::::::.:.: . .:..
XP_011 YVALNKDGTPREGTRTKRHQKFTHFLPRPVDPDKVPELYKDILSQS
120 130 140 150
>>XP_005248321 (OMIM: 149730,180920,602115) PREDICTED: f (208 aa)
initn: 405 init1: 298 opt: 413 Z-score: 529.4 bits: 104.9 E(85289): 9.5e-23
Smith-Waterman score: 413; 43.4% identity (78.7% similar) in 136 aa overlap (53-188:70-203)
30 40 50 60 70 80
pF1KE0 GNVPLADSPGFLNERLGQIEGKLQRGSPTDFAHLKGILRRRQLYCRTGFHLEIFPNGTVH
. ::.: .: :.:. : . :.: :: :
XP_005 LGQDMVSPEATNSSSSSFSSPSSAGRHVRSYNHLQGDVRWRKLFSFTKYFLKIEKNGKVS
40 50 60 70 80 90
90 100 110 120 130 140
pF1KE0 GTRHDHSRFGILEFISLAVGLISIRGVDSGLYLGMNERGELYGSKKLTRECVFREQFEEN
::.... ..:::. :. .:........:. ::.::..:.:::::... .: ..:..:::
XP_005 GTKKENCPYSILEITSVEIGVVAVKAINSNYYLAMNKKGKLYGSKEFNNDCKLKERIEEN
100 110 120 130 140 150
150 160 170 180 190 200
pF1KE0 WYNTYASTLYKHSDSERQYYVALNKDGSPREGYRTKRHQKFTHFLPRPVDPSKLPSMSRD
:::::: ..:. ::.::::: :.::.: .:.:.. .::::
XP_005 GYNTYASFNWQHNG--RQMYVALNGKGAPRRGQKTRRKNTSAHFLPMVVHS
160 170 180 190 200
pF1KE0 LFHYR
>>NP_004456 (OMIM: 149730,180920,602115) fibroblast grow (208 aa)
initn: 405 init1: 298 opt: 413 Z-score: 529.4 bits: 104.9 E(85289): 9.5e-23
Smith-Waterman score: 413; 43.4% identity (78.7% similar) in 136 aa overlap (53-188:70-203)
30 40 50 60 70 80
pF1KE0 GNVPLADSPGFLNERLGQIEGKLQRGSPTDFAHLKGILRRRQLYCRTGFHLEIFPNGTVH
. ::.: .: :.:. : . :.: :: :
NP_004 LGQDMVSPEATNSSSSSFSSPSSAGRHVRSYNHLQGDVRWRKLFSFTKYFLKIEKNGKVS
40 50 60 70 80 90
90 100 110 120 130 140
pF1KE0 GTRHDHSRFGILEFISLAVGLISIRGVDSGLYLGMNERGELYGSKKLTRECVFREQFEEN
::.... ..:::. :. .:........:. ::.::..:.:::::... .: ..:..:::
NP_004 GTKKENCPYSILEITSVEIGVVAVKAINSNYYLAMNKKGKLYGSKEFNNDCKLKERIEEN
100 110 120 130 140 150
150 160 170 180 190 200
pF1KE0 WYNTYASTLYKHSDSERQYYVALNKDGSPREGYRTKRHQKFTHFLPRPVDPSKLPSMSRD
:::::: ..:. ::.::::: :.::.: .:.:.. .::::
NP_004 GYNTYASFNWQHNG--RQMYVALNGKGAPRRGQKTRRKNTSAHFLPMVVHS
160 170 180 190 200
pF1KE0 LFHYR
>>NP_065688 (OMIM: 605831) fibroblast growth factor 22 i (170 aa)
initn: 390 init1: 305 opt: 403 Z-score: 517.9 bits: 102.5 E(85289): 4.2e-22
Smith-Waterman score: 403; 45.1% identity (76.1% similar) in 142 aa overlap (47-188:28-166)
20 30 40 50 60 70
pF1KE0 GFSSSLGNVPLADSPGFLNERLGQIEGKLQRGSPTDFAHLKGILRRRQLYCRTGFHLEIF
:: : .. ::.: .: :.:. : : :..
NP_065 MRRRLWLGLAWLLLARAPDAAGTPSASRG-PRSYPHLEGDVRWRRLFSSTHFFLRVD
10 20 30 40 50
80 90 100 110 120 130
pF1KE0 PNGTVHGTRHDHSRFGILEFISLAVGLISIRGVDSGLYLGMNERGELYGSKKLTRECVFR
:.: :.::: :.. .:::. :. ::.. :..:.::.:..::.::.::::. : .: ::
NP_065 PGGRVQGTRWRHGQDSILEIRSVHVGVVVIKAVSSGFYVAMNRRGRLYGSRLYTVDCRFR
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE0 EQFEENWYNTYASTLYKHSDSERQYYVALNKDGSPREGYRTKRHQKFTHFLPRPVDPSKL
:..::: .::::: ... . ...::.. :.:: : ::.:.. .::::
NP_065 ERIEENGHNTYASQRWRRRG--QPMFLALDRRGGPRPGGRTRRYHLSAHFLPVLVS
120 130 140 150 160 170
200
pF1KE0 PSMSRDLFHYR
>>NP_001308876 (OMIM: 601515,609307) fibroblast growth f (200 aa)
initn: 425 init1: 370 opt: 401 Z-score: 514.4 bits: 102.1 E(85289): 6.5e-22
Smith-Waterman score: 401; 39.2% identity (74.5% similar) in 153 aa overlap (49-199:15-164)
20 30 40 50 60 70
pF1KE0 SSSLGNVPLADSPGFLNERLGQIEGKLQRGSPTDFAHLKGILRRRQLYCRTGFHLEIFPN
.::: .::::. : :::: :..:.. :.
NP_001 MLQCLCGKSLKKNKNPTD-PQLKGIVTR--LYCRQGYYLQMHPD
10 20 30 40
80 90 100 110 120 130
pF1KE0 GTVHGTRHDHSRFGILEFISLAVGLISIRGVDSGLYLGMNERGELYGSKKLTRECVFREQ
:.. ::. : . ....: ... ...:.:: .:::..:: .: :: :. .: :: :.:.
NP_001 GALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFTPECKFKES
50 60 70 80 90 100
140 150 160 170 180 190
pF1KE0 FEENWYNTYASTLYKHSDSERQYYVALNKDGSPREGYRTKRHQKFTHFLPRPVDPS--KL
::.: :.: ::....: : ....:::.:. .: :.:. . .::::.:.. . .
NP_001 VFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPAAHFLPKPLEVAMYRE
110 120 130 140 150 160
200
pF1KE0 PSMSRDLFHYR
::.
NP_001 PSLHDVGETVPKPGVTPSKSTSASAIMNGGKPVNKSKTT
170 180 190 200
>>NP_001308877 (OMIM: 601515,609307) fibroblast growth f (213 aa)
initn: 425 init1: 370 opt: 401 Z-score: 514.1 bits: 102.1 E(85289): 6.8e-22
Smith-Waterman score: 401; 39.2% identity (74.5% similar) in 153 aa overlap (49-199:28-177)
20 30 40 50 60 70
pF1KE0 SSSLGNVPLADSPGFLNERLGQIEGKLQRGSPTDFAHLKGILRRRQLYCRTGFHLEIFPN
.::: .::::. : :::: :..:.. :.
NP_001 MWFLWNIFSKGTHMLQCLCGKSLKKNKNPTD-PQLKGIVTR--LYCRQGYYLQMHPD
10 20 30 40 50
80 90 100 110 120 130
pF1KE0 GTVHGTRHDHSRFGILEFISLAVGLISIRGVDSGLYLGMNERGELYGSKKLTRECVFREQ
:.. ::. : . ....: ... ...:.:: .:::..:: .: :: :. .: :: :.:.
NP_001 GALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFTPECKFKES
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE0 FEENWYNTYASTLYKHSDSERQYYVALNKDGSPREGYRTKRHQKFTHFLPRPVDPS--KL
::.: :.: ::....: : ....:::.:. .: :.:. . .::::.:.. . .
NP_001 VFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPAAHFLPKPLEVAMYRE
120 130 140 150 160 170
200
pF1KE0 PSMSRDLFHYR
::.
NP_001 PSLHDVGETVPKPGVTPSKSTSASAIMNGGKPVNKSKTT
180 190 200 210
>>NP_001308874 (OMIM: 601515,609307) fibroblast growth f (213 aa)
initn: 425 init1: 370 opt: 401 Z-score: 514.1 bits: 102.1 E(85289): 6.8e-22
Smith-Waterman score: 401; 39.2% identity (74.5% similar) in 153 aa overlap (49-199:28-177)
20 30 40 50 60 70
pF1KE0 SSSLGNVPLADSPGFLNERLGQIEGKLQRGSPTDFAHLKGILRRRQLYCRTGFHLEIFPN
.::: .::::. : :::: :..:.. :.
NP_001 MWFLWNIFSKGTHMLQCLCGKSLKKNKNPTD-PQLKGIVTR--LYCRQGYYLQMHPD
10 20 30 40 50
80 90 100 110 120 130
pF1KE0 GTVHGTRHDHSRFGILEFISLAVGLISIRGVDSGLYLGMNERGELYGSKKLTRECVFREQ
:.. ::. : . ....: ... ...:.:: .:::..:: .: :: :. .: :: :.:.
NP_001 GALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFTPECKFKES
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE0 FEENWYNTYASTLYKHSDSERQYYVALNKDGSPREGYRTKRHQKFTHFLPRPVDPS--KL
::.: :.: ::....: : ....:::.:. .: :.:. . .::::.:.. . .
NP_001 VFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPAAHFLPKPLEVAMYRE
120 130 140 150 160 170
200
pF1KE0 PSMSRDLFHYR
::.
NP_001 PSLHDVGETVPKPGVTPSKSTSASAIMNGGKPVNKSKTT
180 190 200 210
207 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 22:22:51 2016 done: Wed Nov 2 22:22:52 2016
Total Scan time: 6.250 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]