FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0574, 290 aa
  1>>>pF1KE0574 290 - 290 aa - 290 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.6043+/-0.000366; mu= 14.9823+/- 0.023
 mean_var=92.7237+/-19.302, 0's: 0 Z-trim(115.6): 20  B-trim: 1487 in 1/52
 Lambda= 0.133192
 statistics sampled from 26213 (26226) to 26213 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.307), width:  16
 Scan time:  6.300

The best scores are:                                      opt bits E(85289)
NP_001073945 (OMIM: 613283,613285) glutaredoxin do ( 290) 1969 388.3 9.5e-108
XP_016865197 (OMIM: 615762,615837) PREDICTED: glut ( 152)  226 53.1 3.9e-07
NP_001073985 (OMIM: 615762,615837) glutaredoxin do ( 248)  226 53.3 5.6e-07


>>NP_001073945 (OMIM: 613283,613285) glutaredoxin domain  (290 aa)
 initn: 1969 init1: 1969 opt: 1969  Z-score: 2055.4  bits: 388.3 E(85289): 9.5e-108
Smith-Waterman score: 1969; 100.0% identity (100.0% similar) in 290 aa overlap (1-290:1-290)

               10        20        30        40        50        60
pF1KE0 MLKREMKPESDRPRKVRFRIASSHSGRVLKEVYEDGQPSGSLDSECASICGIDGLGDSDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLKREMKPESDRPRKVRFRIASSHSGRVLKEVYEDGQPSGSLDSECASICGIDGLGDSDG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 QQNGHIESEGDENENDQDSLLVLARAASEKGFGTRRVNILSKNGTVRGVKYKVSAGQALF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQNGHIESEGDENENDQDSLLVLARAASEKGFGTRRVNILSKNGTVRGVKYKVSAGQALF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 NNLTKVLQQPSTDLEFDRVVIYTTCLRVVRTTFERCELVRKIFQNHRVKFEEKNIALNGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNLTKVLQQPSTDLEFDRVVIYTTCLRVVRTTFERCELVRKIFQNHRVKFEEKNIALNGE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 YGKELDERCRRVSEAPSLPVVFIDGHYLGGAEKILSMNESGELQDILTKIERVQHPHECP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGKELDERCRRVSEAPSLPVVFIDGHYLGGAEKILSMNESGELQDILTKIERVQHPHECP
              190       200       210       220       230       240

              250       260       270       280       290
pF1KE0 SCGGFGFLPCSVCHGSKMSMFRNCFTDSFKALKCTACNENGLQRCKNCAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCGGFGFLPCSVCHGSKMSMFRNCFTDSFKALKCTACNENGLQRCKNCAG
              250       260       270       280       290

>>XP_016865197 (OMIM: 615762,615837) PREDICTED: glutared  (152 aa)
 initn: 311 init1: 201 opt: 226  Z-score: 249.1  bits: 53.1 E(85289): 3.9e-07
Smith-Waterman score: 309; 35.8% identity (60.0% similar) in 165 aa overlap (125-288:12-150)

          100       110       120       130       140       150    
pF1KE0 RRVNILSKNGTVRGVKYKVSAGQALFNNLTKVLQQPSTDLEFDRVVIYTTCLRVVRTTFE
                                     .:  ::   ..: ...:::. :...:: ..
XP_016                    MKSDVRFPLQLRVCLQPLPIIDFGKIIIYTNNLKIIRTPMD
                                  10        20        30        40 

          160       170       180       190       200       210    
pF1KE0 RCELVRKIFQNHRVKFEEKNIALNGEYGKELDERCRRVSEAPSLPVVFIDGHYLGGAEKI
       . ..::::.:...   ::. .  .  :: . :.. :        :.:         ::. 
XP_016 KRDFVRKILQKEEEAEEESLMNKEESYGGR-DQHDR--------PLVE--------AEST
              50        60        70                 80            

          220       230        240       250       260       270   
pF1KE0 LSMNESGELQDILTKIERVQHPHE-CPSCGGFGFLPCSVCHGSKMSMFRNCFTDSFKALK
       : .:.  .  ::         :.. :  : : :   ::.:::::.::. : : .:..::.
XP_016 LPQNRYTQEGDI---------PEDSCFHCRGSGSATCSLCHGSKFSMLANRFKESYRALR
           90                100       110       120       130     

           280       290
pF1KE0 CTACNENGLQRCKNCAG
       : :::::::: :. :  
XP_016 CPACNENGLQPCQICNQ
         140       150  

>>NP_001073985 (OMIM: 615762,615837) glutaredoxin domain  (248 aa)
 initn: 463 init1: 201 opt: 226  Z-score: 246.2  bits: 53.3 E(85289): 5.6e-07
Smith-Waterman score: 433; 33.3% identity (57.3% similar) in 288 aa overlap (3-288:5-246)

                 10         20        30        40        50       
pF1KE0   MLKREMKPESD-RPRKVRFRIASSHSGRVLKEVYEDGQPSGSLDSECASICGIDGLGD
           ..... .:: .::::::.:.::.::::::.:.::::   :   :       ..:  
NP_001 MEDPEKKLNQKSDGKPRKVRFKISSSYSGRVLKQVFEDGQELESPKEEYPHSFLQESLET
               10        20        30        40        50        60

        60        70        80        90       100       110       
pF1KE0 SDGQQNGHIESEGDENENDQDSLLVLARAASEKGFGTRRVNILSKNGTVRGVKYKVSAGQ
        ::     . . : :    :          : : . ..:.... .     :  : ...::
NP_001 MDG-----VYGSG-EVPRPQ--------MCSPK-LTAQRISVFRE-----GNAYTLAGGQ
                     70                 80        90            100

       120       130       140       150       160       170       
pF1KE0 ALFNNLTKVLQQPSTDLEFDRVVIYTTCLRVVRTTFERCELVRKIFQNHRVKFEEKNIAL
         ::.     ..:   ..: ...:::. :...:: ... ..::::.:...   ::. .  
NP_001 PRFNDYKANDHKPLPIIDFGKIIIYTNNLKIIRTPMDKRDFVRKILQKEEEAEEESLMNK
              110       120       130       140       150       160

       180       190       200       210       220       230       
pF1KE0 NGEYGKELDERCRRVSEAPSLPVVFIDGHYLGGAEKILSMNESGELQDILTKIERVQHPH
       .  :: . :.. :        :.:         ::. : .:.  .  ::         :.
NP_001 EESYGGR-DQHDR--------PLVE--------AESTLPQNRYTQEGDI---------PE
               170                       180       190             

        240       250       260       270       280       290
pF1KE0 E-CPSCGGFGFLPCSVCHGSKMSMFRNCFTDSFKALKCTACNENGLQRCKNCAG
       . :  : : :   ::.:::::.::. : : .:..::.: :::::::: :. :  
NP_001 DSCFHCRGSGSATCSLCHGSKFSMLANRFKESYRALRCPACNENGLQPCQICNQ
          200       210       220       230       240        




290 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 22:38:33 2016 done: Wed Nov  2 22:38:34 2016
 Total Scan time:  6.300 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]