Result of FASTA (omim) for
pF1KE0563
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0563, 222 aa
1>>>pF1KE0563 222 - 222 aa - 222 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2001+/-0.000334; mu= 14.5499+/- 0.021
mean_var=65.0196+/-13.160, 0's: 0 Z-trim(113.9): 35 B-trim: 38 in 1/52
Lambda= 0.159057
statistics sampled from 23378 (23413) to 23378 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.653), E-opt: 0.2 (0.275), width: 16
Scan time: 4.640
The best scores are: opt bits E(85289)
NP_714543 (OMIM: 607605) glutathione S-transferase ( 222) 1423 335.0 5.9e-92
NP_665683 (OMIM: 138359) glutathione S-transferase ( 222) 1287 303.8 1.5e-82
NP_000837 (OMIM: 138360) glutathione S-transferase ( 222) 1265 298.8 4.8e-81
XP_011512834 (OMIM: 138360) PREDICTED: glutathione ( 222) 1265 298.8 4.8e-81
NP_000838 (OMIM: 605449) glutathione S-transferase ( 222) 1222 288.9 4.5e-78
XP_005249091 (OMIM: 138359) PREDICTED: glutathione ( 225) 1035 246.0 3.8e-65
XP_016866283 (OMIM: 605449) PREDICTED: glutathione ( 172) 962 229.2 3.3e-60
XP_006715135 (OMIM: 605449) PREDICTED: glutathione ( 172) 962 229.2 3.3e-60
XP_005249092 (OMIM: 605450) PREDICTED: glutathione ( 222) 822 197.1 1.9e-50
NP_001503 (OMIM: 605450) glutathione S-transferase ( 222) 822 197.1 1.9e-50
NP_001305988 (OMIM: 138359) glutathione S-transfer ( 129) 741 178.4 4.8e-45
XP_011512835 (OMIM: 605449) PREDICTED: glutathione ( 129) 696 168.1 6.2e-42
XP_011512836 (OMIM: 605450) PREDICTED: glutathione ( 185) 618 150.3 2e-36
XP_011512837 (OMIM: 605450) PREDICTED: glutathione ( 185) 618 150.3 2e-36
NP_000843 (OMIM: 134660) glutathione S-transferase ( 210) 279 72.5 5.9e-13
NP_055300 (OMIM: 602598) hematopoietic prostagland ( 199) 241 63.8 2.4e-10
NP_000840 (OMIM: 138390) glutathione S-transferase ( 225) 218 58.5 1e-08
NP_000839 (OMIM: 138380) glutathione S-transferase ( 218) 212 57.1 2.6e-08
NP_000552 (OMIM: 138350) glutathione S-transferase ( 218) 204 55.3 9.3e-08
NP_000841 (OMIM: 138333) glutathione S-transferase ( 218) 201 54.6 1.5e-07
NP_001135840 (OMIM: 138380) glutathione S-transfer ( 191) 198 53.9 2.2e-07
NP_671489 (OMIM: 138333) glutathione S-transferase ( 195) 185 50.9 1.7e-06
XP_016856574 (OMIM: 138333) PREDICTED: glutathione ( 254) 185 51.0 2.2e-06
NP_000842 (OMIM: 138385) glutathione S-transferase ( 218) 180 49.8 4.2e-06
XP_005270841 (OMIM: 138385) PREDICTED: glutathione ( 218) 180 49.8 4.2e-06
NP_665877 (OMIM: 603758) maleylacetoacetate isomer ( 216) 179 49.6 4.9e-06
XP_005270839 (OMIM: 138350) PREDICTED: glutathione ( 184) 173 48.2 1.1e-05
XP_016856576 (OMIM: 138333) PREDICTED: glutathione ( 177) 169 47.2 2e-05
NP_001299589 (OMIM: 603758) maleylacetoacetate iso ( 161) 157 44.4 0.00013
NP_666533 (OMIM: 138350) glutathione S-transferase ( 181) 156 44.2 0.00016
XP_016856575 (OMIM: 138333) PREDICTED: glutathione ( 213) 153 43.6 0.0003
>>NP_714543 (OMIM: 607605) glutathione S-transferase A5 (222 aa)
initn: 1423 init1: 1423 opt: 1423 Z-score: 1771.9 bits: 335.0 E(85289): 5.9e-92
Smith-Waterman score: 1423; 100.0% identity (100.0% similar) in 222 aa overlap (1-222:1-222)
10 20 30 40 50 60
pF1KE0 MAEKPKLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_714 MAEKPKLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_714 DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_714 TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPL
130 140 150 160 170 180
190 200 210 220
pF1KE0 LKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFRF
::::::::::::::::::::::::::::::::::::::::::
NP_714 LKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFRF
190 200 210 220
>>NP_665683 (OMIM: 138359) glutathione S-transferase A1 (222 aa)
initn: 1287 init1: 1287 opt: 1287 Z-score: 1603.3 bits: 303.8 E(85289): 1.5e-82
Smith-Waterman score: 1287; 90.1% identity (94.6% similar) in 222 aa overlap (1-222:1-222)
10 20 30 40 50 60
pF1KE0 MAEKPKLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEI
::::::::: :::: ::: ::::::::::.::::..:::::::::::: :.:::::::::
NP_665 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK
:::::::::::::::::::::::::.::::::::: :::.:: :::::: .: :::.:::
NP_665 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPL
::.::::::::::::::::::: :::::::::: ::::::::.::::::::::::::::
NP_665 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL
130 140 150 160 170 180
190 200 210 220
pF1KE0 LKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFRF
:::::::::::::::::::::: :::::::::::::::::::
NP_665 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF
190 200 210 220
>>NP_000837 (OMIM: 138360) glutathione S-transferase A2 (222 aa)
initn: 1265 init1: 1265 opt: 1265 Z-score: 1576.0 bits: 298.8 E(85289): 4.8e-81
Smith-Waterman score: 1265; 88.7% identity (94.6% similar) in 222 aa overlap (1-222:1-222)
10 20 30 40 50 60
pF1KE0 MAEKPKLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEI
::::::::::: :: ::::::::::::::.::::..:::::::::::: :.:::::::::
NP_000 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK
:::::::::::::::::::::::::.::.:::::: :::.:: :::::: . ::::.:::
NP_000 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPL
::..:: ::::::::::::::: :::::::::: ::::::::.::::::::::::::::
NP_000 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL
130 140 150 160 170 180
190 200 210 220
pF1KE0 LKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFRF
:::::::::::::::::::::: ::::::::::::.::::::
NP_000 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF
190 200 210 220
>>XP_011512834 (OMIM: 138360) PREDICTED: glutathione S-t (222 aa)
initn: 1265 init1: 1265 opt: 1265 Z-score: 1576.0 bits: 298.8 E(85289): 4.8e-81
Smith-Waterman score: 1265; 88.7% identity (94.6% similar) in 222 aa overlap (1-222:1-222)
10 20 30 40 50 60
pF1KE0 MAEKPKLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEI
::::::::::: :: ::::::::::::::.::::..:::::::::::: :.:::::::::
XP_011 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK
:::::::::::::::::::::::::.::.:::::: :::.:: :::::: . ::::.:::
XP_011 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPL
::..:: ::::::::::::::: :::::::::: ::::::::.::::::::::::::::
XP_011 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL
130 140 150 160 170 180
190 200 210 220
pF1KE0 LKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFRF
:::::::::::::::::::::: ::::::::::::.::::::
XP_011 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF
190 200 210 220
>>NP_000838 (OMIM: 605449) glutathione S-transferase A3 (222 aa)
initn: 1222 init1: 1222 opt: 1222 Z-score: 1522.7 bits: 288.9 E(85289): 4.5e-78
Smith-Waterman score: 1222; 85.6% identity (93.2% similar) in 222 aa overlap (1-222:1-222)
10 20 30 40 50 60
pF1KE0 MAEKPKLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEI
:: :::::: :.:: :: :::::::::::.::::. ::::: ::::::::.:::::::::
NP_000 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK
:::::::::::::::::::::::::.::::::::::::..::.:::::: .:.:::.:::
NP_000 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPL
::.::: :.::::::::::.:: :::::::::: ::: ::::.::::::::::::.:::
NP_000 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL
130 140 150 160 170 180
190 200 210 220
pF1KE0 LKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFRF
:::::::::::::::::::::: :::: : :.::::::::::
NP_000 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF
190 200 210 220
>>XP_005249091 (OMIM: 138359) PREDICTED: glutathione S-t (225 aa)
initn: 1035 init1: 1035 opt: 1035 Z-score: 1290.7 bits: 246.0 E(85289): 3.8e-65
Smith-Waterman score: 1035; 88.5% identity (94.0% similar) in 182 aa overlap (1-182:1-182)
10 20 30 40 50 60
pF1KE0 MAEKPKLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEI
::::::::: :::: ::: ::::::::::.::::..:::::::::::: :.:::::::::
XP_005 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK
:::::::::::::::::::::::::.::::::::: :::.:: :::::: .: :::.:::
XP_005 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPL
::.::::::::::::::::::: :::::::::: ::::::::.::::::::::::::::
XP_005 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL
130 140 150 160 170 180
190 200 210 220
pF1KE0 LKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFRF
::
XP_005 LKVTHFTAQRGSPTSPILGSCIWALRLTKFCPSLLQAFSAPRSPK
190 200 210 220
>>XP_016866283 (OMIM: 605449) PREDICTED: glutathione S-t (172 aa)
initn: 962 init1: 962 opt: 962 Z-score: 1201.9 bits: 229.2 E(85289): 3.3e-60
Smith-Waterman score: 962; 86.6% identity (94.8% similar) in 172 aa overlap (51-222:1-172)
30 40 50 60 70 80
pF1KE0 WLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEIDGMKLVQTRAILNYIASKYN
.:::::::::::::::::::::::::::::
XP_016 MFQQVPMVEIDGMKLVQTRAILNYIASKYN
10 20 30
90 100 110 120 130 140
pF1KE0 LYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAKTALVKEKIKNRYFPAFEKVL
:::::.::::::::::::..::.:::::: .:.:::.::: ::.::: :.::::::::::
XP_016 LYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVL
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE0 KSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPLLKALKTRISNLPTVKKFLQP
.:: :::::::::: ::: ::::.::::::::::::.:::::::::::::::::::::::
XP_016 QSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKALKTRISNLPTVKKFLQP
100 110 120 130 140 150
210 220
pF1KE0 GSQRKPPMDEKSLEEARKIFRF
:: :::: : :.::::::::::
XP_016 GSPRKPPADAKALEEARKIFRF
160 170
>>XP_006715135 (OMIM: 605449) PREDICTED: glutathione S-t (172 aa)
initn: 962 init1: 962 opt: 962 Z-score: 1201.9 bits: 229.2 E(85289): 3.3e-60
Smith-Waterman score: 962; 86.6% identity (94.8% similar) in 172 aa overlap (51-222:1-172)
30 40 50 60 70 80
pF1KE0 WLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEIDGMKLVQTRAILNYIASKYN
.:::::::::::::::::::::::::::::
XP_006 MFQQVPMVEIDGMKLVQTRAILNYIASKYN
10 20 30
90 100 110 120 130 140
pF1KE0 LYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAKTALVKEKIKNRYFPAFEKVL
:::::.::::::::::::..::.:::::: .:.:::.::: ::.::: :.::::::::::
XP_006 LYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVL
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE0 KSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPLLKALKTRISNLPTVKKFLQP
.:: :::::::::: ::: ::::.::::::::::::.:::::::::::::::::::::::
XP_006 QSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKALKTRISNLPTVKKFLQP
100 110 120 130 140 150
210 220
pF1KE0 GSQRKPPMDEKSLEEARKIFRF
:: :::: : :.::::::::::
XP_006 GSPRKPPADAKALEEARKIFRF
160 170
>>XP_005249092 (OMIM: 605450) PREDICTED: glutathione S-t (222 aa)
initn: 822 init1: 822 opt: 822 Z-score: 1026.6 bits: 197.1 E(85289): 1.9e-50
Smith-Waterman score: 822; 53.4% identity (84.2% similar) in 221 aa overlap (1-221:1-221)
10 20 30 40 50 60
pF1KE0 MAEKPKLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEI
:: .::::: :.:: :::.::.:::::::..:.:::. :.: ::.. . :::::::::::
XP_005 MAARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK
:::::::::.::.:::.:.::.::..:::.:::::.:: .:: :.... . .:.... .
XP_005 DGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPL
.. . .: ::::.:::.:..: :..::::.:: ::. :.. . .:: ...:.::.
XP_005 VVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPF
130 140 150 160 170 180
190 200 210 220
pF1KE0 LKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFRF
:. ...::.::.:.::.:::..::: :: .. . .:::
XP_005 LQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFRP
190 200 210 220
>>NP_001503 (OMIM: 605450) glutathione S-transferase A4 (222 aa)
initn: 822 init1: 822 opt: 822 Z-score: 1026.6 bits: 197.1 E(85289): 1.9e-50
Smith-Waterman score: 822; 53.4% identity (84.2% similar) in 221 aa overlap (1-221:1-221)
10 20 30 40 50 60
pF1KE0 MAEKPKLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEI
:: .::::: :.:: :::.::.:::::::..:.:::. :.: ::.. . :::::::::::
NP_001 MAARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK
:::::::::.::.:::.:.::.::..:::.:::::.:: .:: :.... . .:.... .
NP_001 DGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPL
.. . .: ::::.:::.:..: :..::::.:: ::. :.. . .:: ...:.::.
NP_001 VVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPF
130 140 150 160 170 180
190 200 210 220
pF1KE0 LKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFRF
:. ...::.::.:.::.:::..::: :: .. . .:::
NP_001 LQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFRP
190 200 210 220
222 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 23:16:43 2016 done: Wed Nov 2 23:16:43 2016
Total Scan time: 4.640 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]