Result of FASTA (omim) for
pF1KE0558
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0558, 401 aa
1>>>pF1KE0558 401 - 401 aa - 401 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3793+/-0.000333; mu= 12.6610+/- 0.021
mean_var=106.4094+/-21.495, 0's: 0 Z-trim(118.4): 72 B-trim: 0 in 0/51
Lambda= 0.124332
statistics sampled from 31145 (31217) to 31145 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.727), E-opt: 0.2 (0.366), width: 16
Scan time: 8.790
The best scores are: opt bits E(85289)
NP_660279 (OMIM: 615313) UDP-GlcNAc:betaGal beta-1 ( 401) 2798 512.3 8.1e-145
XP_005247010 (OMIM: 615313) PREDICTED: UDP-GlcNAc: ( 328) 2293 421.7 1.3e-117
XP_011525928 (OMIM: 605863) PREDICTED: N-acetyllac ( 372) 997 189.3 1.4e-47
NP_055071 (OMIM: 605863) N-acetyllactosaminide bet ( 372) 997 189.3 1.4e-47
NP_619651 (OMIM: 615315) acetylgalactosaminyl-O-gl ( 384) 967 183.9 5.8e-46
NP_001317421 (OMIM: 605864) N-acetyllactosaminide ( 353) 917 174.9 2.7e-43
NP_110392 (OMIM: 605864) N-acetyllactosaminide bet ( 378) 917 174.9 2.9e-43
NP_006568 (OMIM: 605581) N-acetyllactosaminide bet ( 397) 877 167.8 4.3e-41
NP_001306004 (OMIM: 605581) N-acetyllactosaminide ( 397) 877 167.8 4.3e-41
XP_011525236 (OMIM: 615357) PREDICTED: UDP-GlcNAc: ( 397) 633 124.0 6.4e-28
NP_940942 (OMIM: 615357) UDP-GlcNAc:betaGal beta-1 ( 397) 633 124.0 6.4e-28
XP_011511527 (OMIM: 615333) PREDICTED: lactosylcer ( 378) 621 121.8 2.8e-27
XP_005247882 (OMIM: 615333) PREDICTED: lactosylcer ( 378) 621 121.8 2.8e-27
XP_016862798 (OMIM: 615333) PREDICTED: lactosylcer ( 378) 621 121.8 2.8e-27
XP_011511531 (OMIM: 615333) PREDICTED: lactosylcer ( 378) 621 121.8 2.8e-27
XP_011511529 (OMIM: 615333) PREDICTED: lactosylcer ( 378) 621 121.8 2.8e-27
XP_011511528 (OMIM: 615333) PREDICTED: lactosylcer ( 378) 621 121.8 2.8e-27
XP_011511530 (OMIM: 615333) PREDICTED: lactosylcer ( 378) 621 121.8 2.8e-27
XP_005247880 (OMIM: 615333) PREDICTED: lactosylcer ( 378) 621 121.8 2.8e-27
NP_114436 (OMIM: 615333) lactosylceramide 1,3-N-ac ( 378) 621 121.8 2.8e-27
XP_005247881 (OMIM: 615333) PREDICTED: lactosylcer ( 378) 621 121.8 2.8e-27
NP_003774 (OMIM: 603018) beta-1,3-galactosyltransf ( 422) 564 111.6 3.6e-24
XP_006712882 (OMIM: 603093) PREDICTED: beta-1,3-ga ( 326) 532 105.8 1.6e-22
XP_005246988 (OMIM: 603093) PREDICTED: beta-1,3-ga ( 326) 532 105.8 1.6e-22
NP_066191 (OMIM: 603093) beta-1,3-galactosyltransf ( 326) 532 105.8 1.6e-22
XP_011510387 (OMIM: 603093) PREDICTED: beta-1,3-ga ( 326) 532 105.8 1.6e-22
XP_016883718 (OMIM: 604066) PREDICTED: beta-1,3-ga ( 310) 502 100.4 6.3e-21
XP_016883727 (OMIM: 604066) PREDICTED: beta-1,3-ga ( 310) 502 100.4 6.3e-21
NP_149361 (OMIM: 604066) beta-1,3-galactosyltransf ( 310) 502 100.4 6.3e-21
XP_016883719 (OMIM: 604066) PREDICTED: beta-1,3-ga ( 310) 502 100.4 6.3e-21
XP_016883726 (OMIM: 604066) PREDICTED: beta-1,3-ga ( 310) 502 100.4 6.3e-21
XP_016883717 (OMIM: 604066) PREDICTED: beta-1,3-ga ( 310) 502 100.4 6.3e-21
XP_016883729 (OMIM: 604066) PREDICTED: beta-1,3-ga ( 310) 502 100.4 6.3e-21
XP_016883728 (OMIM: 604066) PREDICTED: beta-1,3-ga ( 310) 502 100.4 6.3e-21
XP_016883725 (OMIM: 604066) PREDICTED: beta-1,3-ga ( 310) 502 100.4 6.3e-21
NP_001265579 (OMIM: 604066) beta-1,3-galactosyltra ( 310) 502 100.4 6.3e-21
XP_016883722 (OMIM: 604066) PREDICTED: beta-1,3-ga ( 310) 502 100.4 6.3e-21
XP_016883720 (OMIM: 604066) PREDICTED: beta-1,3-ga ( 310) 502 100.4 6.3e-21
NP_149360 (OMIM: 604066) beta-1,3-galactosyltransf ( 310) 502 100.4 6.3e-21
XP_016883721 (OMIM: 604066) PREDICTED: beta-1,3-ga ( 310) 502 100.4 6.3e-21
XP_016883716 (OMIM: 604066) PREDICTED: beta-1,3-ga ( 310) 502 100.4 6.3e-21
XP_016883730 (OMIM: 604066) PREDICTED: beta-1,3-ga ( 310) 502 100.4 6.3e-21
NP_006048 (OMIM: 604066) beta-1,3-galactosyltransf ( 310) 502 100.4 6.3e-21
XP_016883724 (OMIM: 604066) PREDICTED: beta-1,3-ga ( 310) 502 100.4 6.3e-21
XP_016883723 (OMIM: 604066) PREDICTED: beta-1,3-ga ( 310) 502 100.4 6.3e-21
NP_149362 (OMIM: 604066) beta-1,3-galactosyltransf ( 314) 502 100.4 6.3e-21
XP_005247916 (OMIM: 111400,603094,615021) PREDICTE ( 331) 469 94.5 4e-19
XP_016862895 (OMIM: 111400,603094,615021) PREDICTE ( 331) 469 94.5 4e-19
NP_149359 (OMIM: 111400,603094,615021) UDP-GalNAc: ( 331) 469 94.5 4e-19
XP_016862897 (OMIM: 111400,603094,615021) PREDICTE ( 331) 469 94.5 4e-19
>>NP_660279 (OMIM: 615313) UDP-GlcNAc:betaGal beta-1,3-N (401 aa)
initn: 2798 init1: 2798 opt: 2798 Z-score: 2720.9 bits: 512.3 E(85289): 8.1e-145
Smith-Waterman score: 2798; 100.0% identity (100.0% similar) in 401 aa overlap (1-401:1-401)
10 20 30 40 50 60
pF1KE0 MSLWKKTVYRSLCLALALLVAVTVFQRSLTPGQFLQEPPPPTLEPQKAQKPNGQLVNPNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_660 MSLWKKTVYRSLCLALALLVAVTVFQRSLTPGQFLQEPPPPTLEPQKAQKPNGQLVNPNN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 FWKNPKDVAAPTPMASQGPQAWDVTTTNCSANINLTHQPWFQVLEPQFRQFLFYRHCRYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_660 FWKNPKDVAAPTPMASQGPQAWDVTTTNCSANINLTHQPWFQVLEPQFRQFLFYRHCRYF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 PMLLNHPEKCRGDVYLLVVVKSVITQHDRREAIRQTWGRERQSAGGGRGAVRTLFLLGTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_660 PMLLNHPEKCRGDVYLLVVVKSVITQHDRREAIRQTWGRERQSAGGGRGAVRTLFLLGTA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 SKQEERTHYQQLLAYEDRLYGDILQWGFLDTFFNLTLKEIHFLKWLDIYCPHVPFIFKGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_660 SKQEERTHYQQLLAYEDRLYGDILQWGFLDTFFNLTLKEIHFLKWLDIYCPHVPFIFKGD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 DDVFVNPTNLLEFLADRQPQENLFVGDVLQHARPIRRKDNKYYIPGALYGKASYPPYAGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_660 DDVFVNPTNLLEFLADRQPQENLFVGDVLQHARPIRRKDNKYYIPGALYGKASYPPYAGG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 GGFLMAGSLARRLHHACDTLELYPIDDVFLGMCLEVLGVQPTAHEGFKTFGISRNRNSRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_660 GGFLMAGSLARRLHHACDTLELYPIDDVFLGMCLEVLGVQPTAHEGFKTFGISRNRNSRM
310 320 330 340 350 360
370 380 390 400
pF1KE0 NKEPCFFRAMLVVHKLLPPELLAMWGLVHSNLTCSRKLQVL
:::::::::::::::::::::::::::::::::::::::::
NP_660 NKEPCFFRAMLVVHKLLPPELLAMWGLVHSNLTCSRKLQVL
370 380 390 400
>>XP_005247010 (OMIM: 615313) PREDICTED: UDP-GlcNAc:beta (328 aa)
initn: 2293 init1: 2293 opt: 2293 Z-score: 2232.6 bits: 421.7 E(85289): 1.3e-117
Smith-Waterman score: 2293; 100.0% identity (100.0% similar) in 328 aa overlap (74-401:1-328)
50 60 70 80 90 100
pF1KE0 EPQKAQKPNGQLVNPNNFWKNPKDVAAPTPMASQGPQAWDVTTTNCSANINLTHQPWFQV
::::::::::::::::::::::::::::::
XP_005 MASQGPQAWDVTTTNCSANINLTHQPWFQV
10 20 30
110 120 130 140 150 160
pF1KE0 LEPQFRQFLFYRHCRYFPMLLNHPEKCRGDVYLLVVVKSVITQHDRREAIRQTWGRERQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEPQFRQFLFYRHCRYFPMLLNHPEKCRGDVYLLVVVKSVITQHDRREAIRQTWGRERQS
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE0 AGGGRGAVRTLFLLGTASKQEERTHYQQLLAYEDRLYGDILQWGFLDTFFNLTLKEIHFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGGGRGAVRTLFLLGTASKQEERTHYQQLLAYEDRLYGDILQWGFLDTFFNLTLKEIHFL
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE0 KWLDIYCPHVPFIFKGDDDVFVNPTNLLEFLADRQPQENLFVGDVLQHARPIRRKDNKYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KWLDIYCPHVPFIFKGDDDVFVNPTNLLEFLADRQPQENLFVGDVLQHARPIRRKDNKYY
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE0 IPGALYGKASYPPYAGGGGFLMAGSLARRLHHACDTLELYPIDDVFLGMCLEVLGVQPTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IPGALYGKASYPPYAGGGGFLMAGSLARRLHHACDTLELYPIDDVFLGMCLEVLGVQPTA
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE0 HEGFKTFGISRNRNSRMNKEPCFFRAMLVVHKLLPPELLAMWGLVHSNLTCSRKLQVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HEGFKTFGISRNRNSRMNKEPCFFRAMLVVHKLLPPELLAMWGLVHSNLTCSRKLQVL
280 290 300 310 320
>>XP_011525928 (OMIM: 605863) PREDICTED: N-acetyllactosa (372 aa)
initn: 980 init1: 720 opt: 997 Z-score: 975.5 bits: 189.3 E(85289): 1.4e-47
Smith-Waterman score: 1001; 44.4% identity (72.1% similar) in 340 aa overlap (65-400:44-371)
40 50 60 70 80 90
pF1KE0 LQEPPPPTLEPQKAQKPNGQLVNPNNFWKNPKDVAAPTPMASQGPQAWDVTTTNCSANIN
:. .: ::: . .: : :: .
XP_011 ILAIGAFTLLLFSLLVSPPTCKVQEQPPAIPEALAWPTPPTRPAPAP-------CHANTS
20 30 40 50 60
100 110 120 130 140 150
pF1KE0 LTHQPWFQVLEPQFRQ-FLFYRHCRYFPMLLN-HPEKCRGDVYLLVVVKSVITQHDRREA
.. .: : . .:: : ::.:::::.::.: . : :: :.::.:.:: ... :::
XP_011 MVTHPDFAT-QPQHVQNFLLYRHCRHFPLLQDVPPSKCAQPVFLLLVIKSSPSNYVRREL
70 80 90 100 110 120
160 170 180 190 200 210
pF1KE0 IRQTWGRERQSAGGGRGAVRTLFLLGTASKQEERTHYQQLLAYEDRLYGDILQWGFLDTF
.:.::::::. : .: :::.::::. .: . ..:: : . .:::::: : :.:
XP_011 LRRTWGRERKVRGL---QLRLLFLVGTASNPHEARKVNRLLELEAQTHGDILQWDFHDSF
130 140 150 160 170 180
220 230 240 250 260 270
pF1KE0 FNLTLKEIHFLKWLDIYCPHVPFIFKGDDDVFVNPTNLLEFLADRQPQENLFVGDVLQHA
::::::.. ::.: . : .. :...::::::.. :.. .: :..: ..::::...:..
XP_011 FNLTLKQVLFLQWQETRCANASFVLNGDDDVFAHTDNMVFYLQDHDPGRHLFVGQLIQNV
190 200 210 220 230 240
280 290 300 310 320 330
pF1KE0 RPIRRKDNKYYIPGALYGKASYPPYAGGGGFLMAGSLARRLHHACDTLELYPIDDVFLGM
::: .:::.: .. . :::: ::::::.. : :..: .:...:::::::::
XP_011 GPIRAFWSKYYVPEVVTQNERYPPYCGGGGFLLSRFTAAALRRAAHVLDIFPIDDVFLGM
250 260 270 280 290 300
340 350 360 370 380 390
pF1KE0 CLEVLGVQPTAHEGFKTFGISRNRNSRMNK-EPCFFRAMLVVHKLLPPELLAMW-GLVHS
:::. :..:..: :..: :. : ..:... .:::.: .:.::..:: :.: :: .: .
XP_011 CLELEGLKPASHSGIRTSGV-RAPSQRLSSFDPCFYRDLLLVHRFLPYEMLLMWDALNQP
310 320 330 340 350 360
400
pF1KE0 NLTCSRKLQVL
::::. . :.
XP_011 NLTCGNQTQIY
370
>>NP_055071 (OMIM: 605863) N-acetyllactosaminide beta-1, (372 aa)
initn: 980 init1: 720 opt: 997 Z-score: 975.5 bits: 189.3 E(85289): 1.4e-47
Smith-Waterman score: 1001; 44.4% identity (72.1% similar) in 340 aa overlap (65-400:44-371)
40 50 60 70 80 90
pF1KE0 LQEPPPPTLEPQKAQKPNGQLVNPNNFWKNPKDVAAPTPMASQGPQAWDVTTTNCSANIN
:. .: ::: . .: : :: .
NP_055 ILAIGAFTLLLFSLLVSPPTCKVQEQPPAIPEALAWPTPPTRPAPAP-------CHANTS
20 30 40 50 60
100 110 120 130 140 150
pF1KE0 LTHQPWFQVLEPQFRQ-FLFYRHCRYFPMLLN-HPEKCRGDVYLLVVVKSVITQHDRREA
.. .: : . .:: : ::.:::::.::.: . : :: :.::.:.:: ... :::
NP_055 MVTHPDFAT-QPQHVQNFLLYRHCRHFPLLQDVPPSKCAQPVFLLLVIKSSPSNYVRREL
70 80 90 100 110 120
160 170 180 190 200 210
pF1KE0 IRQTWGRERQSAGGGRGAVRTLFLLGTASKQEERTHYQQLLAYEDRLYGDILQWGFLDTF
.:.::::::. : .: :::.::::. .: . ..:: : . .:::::: : :.:
NP_055 LRRTWGRERKVRGL---QLRLLFLVGTASNPHEARKVNRLLELEAQTHGDILQWDFHDSF
130 140 150 160 170 180
220 230 240 250 260 270
pF1KE0 FNLTLKEIHFLKWLDIYCPHVPFIFKGDDDVFVNPTNLLEFLADRQPQENLFVGDVLQHA
::::::.. ::.: . : .. :...::::::.. :.. .: :..: ..::::...:..
NP_055 FNLTLKQVLFLQWQETRCANASFVLNGDDDVFAHTDNMVFYLQDHDPGRHLFVGQLIQNV
190 200 210 220 230 240
280 290 300 310 320 330
pF1KE0 RPIRRKDNKYYIPGALYGKASYPPYAGGGGFLMAGSLARRLHHACDTLELYPIDDVFLGM
::: .:::.: .. . :::: ::::::.. : :..: .:...:::::::::
NP_055 GPIRAFWSKYYVPEVVTQNERYPPYCGGGGFLLSRFTAAALRRAAHVLDIFPIDDVFLGM
250 260 270 280 290 300
340 350 360 370 380 390
pF1KE0 CLEVLGVQPTAHEGFKTFGISRNRNSRMNK-EPCFFRAMLVVHKLLPPELLAMW-GLVHS
:::. :..:..: :..: :. : ..:... .:::.: .:.::..:: :.: :: .: .
NP_055 CLELEGLKPASHSGIRTSGV-RAPSQRLSSFDPCFYRDLLLVHRFLPYEMLLMWDALNQP
310 320 330 340 350 360
400
pF1KE0 NLTCSRKLQVL
::::. . :.
NP_055 NLTCGNQTQIY
370
>>NP_619651 (OMIM: 615315) acetylgalactosaminyl-O-glycos (384 aa)
initn: 946 init1: 678 opt: 967 Z-score: 946.2 bits: 183.9 E(85289): 5.8e-46
Smith-Waterman score: 980; 42.2% identity (67.1% similar) in 374 aa overlap (34-400:30-383)
10 20 30 40 50 60
pF1KE0 WKKTVYRSLCLALALLVAVTVFQRSLTPGQFLQEPPPPTLE--PQKAQKPNGQLVNPNNF
::: : : : ::. . :.:
NP_619 MAFPCRRSLTAKTLACLLVGVSFLALQQWFLQAPRSPREERSPQE-ETPEG--------
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 WKNPKDVAAPTPMASQGPQAWDVTTTNCSANINLTHQPWFQVLEPQFRQFLFYRHCRYFP
: : :: :.. : . : : :: . . :. : ....:: :::::.::
NP_619 ---PTD--AP---AADEPPSELVPGPPCVANASANATADFEQLPARIQDFLRYRHCRHFP
60 70 80 90 100
130 140 150 160 170
pF1KE0 MLLNHPEKCRGD--VYLLVVVKSVITQHDRREAIRQTWGRERQSAGGGRGAVRTLFLLGT
.: . : :: : :.::..:::. ...::: ::.:::.:: . ::: :: ::::::
NP_619 LLWDAPAKCAGGRGVFLLLAVKSAPEHYERRELIRRTWGQER--SYGGR-PVRRLFLLGT
110 120 130 140 150
180 190 200 210 220 230
pF1KE0 ASKQEERT--HYQQLLAYEDRLYGDILQWGFLDTFFNLTLKEIHFLKWLDIYCPHVPFIF
. ..: . .:.: : : .::.:::.: :::.:::::..:.: :: :::. :..
NP_619 PGPEDEARAERLAELVALEAREHGDVLQWAFADTFLNLTLKHLHLLDWLAARCPHARFLL
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE0 KGDDDVFVNPTNLLEFLADRQPQENLFVGDVLQHARPIRRKDNKYYIPGALYGKASYPPY
.:::::::. .:...:: . : ..:: :.... . ::: . .::..: :. ..:: :
NP_619 SGDDDVFVHTANVVRFLQAQPPGRHLFSGQLMEGSVPIRDSWSKYFVPPQLFPGSAYPVY
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE0 AGGGGFLMAGSLARRLHHACDTLELYPIDDVFLGMCLEVLGVQPTAHEGFKTFGISRNRN
.:::::..: :: :. : :.::::...::::: :. :..:::.. ::..
NP_619 CSGGGFLLSGPTARALRAAARHTPLFPIDDAYMGMCLERAGLAPSGHEGIRPFGVQLPGA
280 290 300 310 320 330
360 370 380 390 400
pF1KE0 SRMNKEPCFFRAMLVVHKLLPPELLAMWGLVHS-NLTCSRKLQVL
.. . .::..: .:.::.. : :.: :: .:: :.:.: .:
NP_619 QQSSFDPCMYRELLLVHRFAPYEMLLMWKALHSPALSCDRGHRVS
340 350 360 370 380
>>NP_001317421 (OMIM: 605864) N-acetyllactosaminide beta (353 aa)
initn: 880 init1: 643 opt: 917 Z-score: 898.2 bits: 174.9 E(85289): 2.7e-43
Smith-Waterman score: 952; 44.3% identity (66.5% similar) in 352 aa overlap (46-395:25-346)
20 30 40 50 60 70
pF1KE0 LALLVAVTVFQRSLTPGQFLQEPPPPTLEPQKAQKPNGQLVNPNNFWKNPKDVAAPTPMA
.:: :: :. . . :: : :::
NP_001 MLCRLCWLVSYSLAVLLLGCLLFLRKAAKPAGDPTAHQPFW------APPTPRH
10 20 30 40
80 90 100 110 120 130
pF1KE0 SQGPQAWDVTTTNCSANINLTHQPWFQVLEPQFRQFLFYRHCRYFPMLLNHPEKCRGDVY
:. : :.... : : . : :: ::::: : .::. : : :..
NP_001 SRCPPNHTVSSASLS-------------LPSRHRLFLTYRHCRNFSILLE-PSGCSKDTF
50 60 70 80 90
140 150 160 170 180 190
pF1KE0 LLVVVKSVITQHDRREAIRQTWGRERQSAGGGRG-AVRTLFLLGTASKQEERTHYQQLLA
::...:: . .:: :::.:::: .: .:: .. .::::.:.. ::::
NP_001 LLLAIKSQPGHVERRAAIRSTWGR---VGGWARGRQLKLVFLLGVAGSAPP----AQLLA
100 110 120 130 140
200 210 220 230 240 250
pF1KE0 YEDRLYGDILQWGFLDTFFNLTLKEIHFLKWLDIYCPHVPFIFKGDDDVFVNPTNLLEFL
::.: . ::::: : . ::::::::.:. .:. ::.. :..::::::::. :.::::
NP_001 YESREFDDILQWDFTEDFFNLTLKELHLQRWVVAACPQAHFMLKGDDDVFVHVPNVLEFL
150 160 170 180 190 200
260 270 280 290 300 310
pF1KE0 ADRQPQENLFVGDVLQHARPIRRKDNKYYIPGALYGKASYPPYAGGGGFLMAGSLARRLH
.: ..:.::::...: : : ::.:: ..: . :::::::::..:. . .:::.
NP_001 DGWDPAQDLLVGDVIRQALPNRNTKVKYFIPPSMYRATHYPPYAGGGGYVMSRATVRRLQ
210 220 230 240 250 260
320 330 340 350 360 370
pF1KE0 HACDTLELYPIDDVFLGMCLEVLGVQPTAHEGFKTFGISRNRNSRMNKEPCFFRAMLVVH
. ::.::::::.::::. ::..: : ::::::: : . .::..:..:.::
NP_001 AIMEDAELFPIDDVFVGMCLRRLGLSPMHHAGFKTFGIRRPLDPL---DPCLYRGLLLVH
270 280 290 300 310 320
380 390 400
pF1KE0 KLLPPELLAMWGLVHSN-LTCSRKLQVL
.: : :. .::.:: .. : :.
NP_001 RLSPLEMWTMWALVTDEGLKCAAGPIPQR
330 340 350
>>NP_110392 (OMIM: 605864) N-acetyllactosaminide beta-1, (378 aa)
initn: 880 init1: 643 opt: 917 Z-score: 897.8 bits: 174.9 E(85289): 2.9e-43
Smith-Waterman score: 952; 44.3% identity (66.5% similar) in 352 aa overlap (46-395:50-371)
20 30 40 50 60 70
pF1KE0 LALLVAVTVFQRSLTPGQFLQEPPPPTLEPQKAQKPNGQLVNPNNFWKNPKDVAAPTPMA
.:: :: :. . . :: : :::
NP_110 LPKGPAMLCRLCWLVSYSLAVLLLGCLLFLRKAAKPAGDPTAHQPFW------APPTPRH
20 30 40 50 60 70
80 90 100 110 120 130
pF1KE0 SQGPQAWDVTTTNCSANINLTHQPWFQVLEPQFRQFLFYRHCRYFPMLLNHPEKCRGDVY
:. : :.... : : . : :: ::::: : .::. : : :..
NP_110 SRCPPNHTVSSASLS-------------LPSRHRLFLTYRHCRNFSILLE-PSGCSKDTF
80 90 100 110
140 150 160 170 180 190
pF1KE0 LLVVVKSVITQHDRREAIRQTWGRERQSAGGGRG-AVRTLFLLGTASKQEERTHYQQLLA
::...:: . .:: :::.:::: .: .:: .. .::::.:.. ::::
NP_110 LLLAIKSQPGHVERRAAIRSTWGR---VGGWARGRQLKLVFLLGVAGSAPP----AQLLA
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE0 YEDRLYGDILQWGFLDTFFNLTLKEIHFLKWLDIYCPHVPFIFKGDDDVFVNPTNLLEFL
::.: . ::::: : . ::::::::.:. .:. ::.. :..::::::::. :.::::
NP_110 YESREFDDILQWDFTEDFFNLTLKELHLQRWVVAACPQAHFMLKGDDDVFVHVPNVLEFL
180 190 200 210 220 230
260 270 280 290 300 310
pF1KE0 ADRQPQENLFVGDVLQHARPIRRKDNKYYIPGALYGKASYPPYAGGGGFLMAGSLARRLH
.: ..:.::::...: : : ::.:: ..: . :::::::::..:. . .:::.
NP_110 DGWDPAQDLLVGDVIRQALPNRNTKVKYFIPPSMYRATHYPPYAGGGGYVMSRATVRRLQ
240 250 260 270 280 290
320 330 340 350 360 370
pF1KE0 HACDTLELYPIDDVFLGMCLEVLGVQPTAHEGFKTFGISRNRNSRMNKEPCFFRAMLVVH
. ::.::::::.::::. ::..: : ::::::: : . .::..:..:.::
NP_110 AIMEDAELFPIDDVFVGMCLRRLGLSPMHHAGFKTFGIRRPLDPL---DPCLYRGLLLVH
300 310 320 330 340
380 390 400
pF1KE0 KLLPPELLAMWGLVHSN-LTCSRKLQVL
.: : :. .::.:: .. : :.
NP_110 RLSPLEMWTMWALVTDEGLKCAAGPIPQR
350 360 370
>>NP_006568 (OMIM: 605581) N-acetyllactosaminide beta-1, (397 aa)
initn: 669 init1: 294 opt: 877 Z-score: 858.7 bits: 167.8 E(85289): 4.3e-41
Smith-Waterman score: 878; 37.8% identity (67.9% similar) in 368 aa overlap (33-394:47-397)
10 20 30 40 50 60
pF1KE0 LWKKTVYRSLCLALALLVAVTVFQRSLTPGQFLQEPPPPTLEPQKAQKPNGQLVNPNNFW
.: . :: .. :. .. ::
NP_006 ANVFIYFIMEVSKSSSQEKNGKGEVIIPKEKFWKISTPPEAYWNREQEKLNRQYNPI---
20 30 40 50 60 70
70 80 90 100 110 120
pF1KE0 KNPKDVAAPTPMASQGPQAWDVTTTN-CSANINLTHQ-PWFQVLEPQFRQFLFYRHCRYF
.. : ..... . ... : : .. .: :. : .:..::.: .:: .
NP_006 -----LSMLTNQTGEAGRLSNISHLNYCEPDLRVTSVVTGFNNLPDRFKDFLLYLRCRNY
80 90 100 110 120
130 140 150 160 170 180
pF1KE0 PMLLNHPEKCRGDVYLLVVVKSVITQHDRREAIRQTWGRERQSAGGGRGAVRTLFLLGTA
.:...:.:: .::...::. . ::.:::..::.: : .:.. .:: .:::: .
NP_006 SLLIDQPDKCAKKPFLLLAIKSLTPHFARRQAIRESWGQE--SNAGNQTVVR-VFLLGQT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 SKQEERTHYQQLLAYEDRLYGDILQWGFLDTFFNLTLKEIHFLKWLDIYCPHVPFIFKGD
.... ...: .:.. . :::.:.. ::::::.:::. ::.:.. :: . :.::::
NP_006 PPEDNHPDLSDMLKFESEKHQDILMWNYRDTFFNLSLKEVLFLRWVSTSCPDTEFVFKGD
190 200 210 220 230 240
250 260 270 280 290
pF1KE0 DDVFVNPTNLLEFLAD--RQPQENLFVGDVLQHARPIRRKDNKYYIPGALYGKASYPPYA
:::::: ..:..: . . ..::.:::...: : : : ::::: ..:. . :::::
NP_006 DDVFVNTHHILNYLNSLSKTKAKDLFIGDVIHNAGPHRDKKLKYYIPEVVYS-GLYPPYA
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE0 GGGGFLMAGSLARRLHHACDTLELYPIDDVFLGMCLEVLGVQPTAHEGFKTFGIS-RNRN
::::::..: :: ::.: : ..:::::::. ::::. ::. : :.::.:: : .:.:
NP_006 GGGGFLYSGHLALRLYHITDQVHLYPIDDVYTGMCLQKLGLVPEKHKGFRTFDIEEKNKN
310 320 330 340 350 360
360 370 380 390 400
pF1KE0 SRMNKEPCFFRAMLVVHKLLPPELLAMWGLVHS-NLTCSRKLQVL
. : . ...::. : :.. .:. ..: .: :
NP_006 N-----ICSYVDLMLVHSRKPQEMIDIWSQLQSAHLKC
370 380 390
>>NP_001306004 (OMIM: 605581) N-acetyllactosaminide beta (397 aa)
initn: 669 init1: 294 opt: 877 Z-score: 858.7 bits: 167.8 E(85289): 4.3e-41
Smith-Waterman score: 878; 37.8% identity (67.9% similar) in 368 aa overlap (33-394:47-397)
10 20 30 40 50 60
pF1KE0 LWKKTVYRSLCLALALLVAVTVFQRSLTPGQFLQEPPPPTLEPQKAQKPNGQLVNPNNFW
.: . :: .. :. .. ::
NP_001 ANVFIYFIMEVSKSSSQEKNGKGEVIIPKEKFWKISTPPEAYWNREQEKLNRQYNPI---
20 30 40 50 60 70
70 80 90 100 110 120
pF1KE0 KNPKDVAAPTPMASQGPQAWDVTTTN-CSANINLTHQ-PWFQVLEPQFRQFLFYRHCRYF
.. : ..... . ... : : .. .: :. : .:..::.: .:: .
NP_001 -----LSMLTNQTGEAGRLSNISHLNYCEPDLRVTSVVTGFNNLPDRFKDFLLYLRCRNY
80 90 100 110 120
130 140 150 160 170 180
pF1KE0 PMLLNHPEKCRGDVYLLVVVKSVITQHDRREAIRQTWGRERQSAGGGRGAVRTLFLLGTA
.:...:.:: .::...::. . ::.:::..::.: : .:.. .:: .:::: .
NP_001 SLLIDQPDKCAKKPFLLLAIKSLTPHFARRQAIRESWGQE--SNAGNQTVVR-VFLLGQT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 SKQEERTHYQQLLAYEDRLYGDILQWGFLDTFFNLTLKEIHFLKWLDIYCPHVPFIFKGD
.... ...: .:.. . :::.:.. ::::::.:::. ::.:.. :: . :.::::
NP_001 PPEDNHPDLSDMLKFESEKHQDILMWNYRDTFFNLSLKEVLFLRWVSTSCPDTEFVFKGD
190 200 210 220 230 240
250 260 270 280 290
pF1KE0 DDVFVNPTNLLEFLAD--RQPQENLFVGDVLQHARPIRRKDNKYYIPGALYGKASYPPYA
:::::: ..:..: . . ..::.:::...: : : : ::::: ..:. . :::::
NP_001 DDVFVNTHHILNYLNSLSKTKAKDLFIGDVIHNAGPHRDKKLKYYIPEVVYS-GLYPPYA
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE0 GGGGFLMAGSLARRLHHACDTLELYPIDDVFLGMCLEVLGVQPTAHEGFKTFGIS-RNRN
::::::..: :: ::.: : ..:::::::. ::::. ::. : :.::.:: : .:.:
NP_001 GGGGFLYSGHLALRLYHITDQVHLYPIDDVYTGMCLQKLGLVPEKHKGFRTFDIEEKNKN
310 320 330 340 350 360
360 370 380 390 400
pF1KE0 SRMNKEPCFFRAMLVVHKLLPPELLAMWGLVHS-NLTCSRKLQVL
. : . ...::. : :.. .:. ..: .: :
NP_001 N-----ICSYVDLMLVHSRKPQEMIDIWSQLQSAHLKC
370 380 390
>>XP_011525236 (OMIM: 615357) PREDICTED: UDP-GlcNAc:beta (397 aa)
initn: 450 init1: 210 opt: 633 Z-score: 622.2 bits: 124.0 E(85289): 6.4e-28
Smith-Waterman score: 660; 33.1% identity (59.0% similar) in 405 aa overlap (12-394:8-397)
10 20 30 40 50
pF1KE0 MSLWKKTVYRSLCL-ALALLVAVTVFQRSLTPGQFLQEPPPPTLEPQKAQKPNGQLVNPN
::: :: :... :. . . ... . : : : . : . . :
XP_011 MRCPKCLLCLSALLTLLGLKVYIEWTSESRLSKAYPSPRGTPPSPTPANPEPTLPA
10 20 30 40 50
60 70 80 90 100
pF1KE0 NFWKNPKDVAAPTPMASQGPQAW--------DVTTTN-CSA--NINLTHQPWFQVLEPQF
:. .. . : :.: . : : : : :. :.: :. : : ..
XP_011 NL-STRLGQTIPLPFAYWNQQQWRLGSLPSGDSTETGGCQAWGAAAATEIPDFASYPKDL
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE0 RQFLFYRHCRYFPMLL-----NHPEKCRG-DV-YLLVVVKSVITQHDRREAIRQTWGRER
:.::. :: ::. : .. .: :: :::..::: . .:.:.:.:::
XP_011 RRFLLSAACRSFPQWLPGGGGSQVSSCSDTDVPYLLLAVKSEPGRFAERQAVRETWG---
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE0 QSAGGGRGAVRTLFLLGTASKQEERTHYQQLLAYEDRLYGDILQWGFLDTFFNLTLKEIH
. : : .: :::::. : ..:.:.:.: :.:.: : :::. :: :::..
XP_011 SPAPG----IRLLFLLGSPVG-EAGPDLDSLVAWESRRYSDLLLWDFLDVPFNQTLKDLL
180 190 200 210 220
230 240 250 260 270
pF1KE0 FLKWLDIYCPHVPFIFKGDDDVFVNPTNLLEFLADRQPQ--ENLFVGDVLQHARPIRRKD
.: :: .:: : :.....::.::. :: : : ..:..:.:. .: :.:.
XP_011 LLAWLGRHCPTVSFVLRAQDDAFVHTPALLAHLRALPPASARSLYLGEVFTQAMPLRKPG
230 240 250 260 270 280
280 290 300 310 320 330
pF1KE0 NKYYIPGALYGKASYPPYAGGGGFLMAGSLARRLHHACDTLELYPIDDVFLGMCLEVLGV
. .:.: ... ...:: ::.:::...:: :: : .: . .:..::. :.:...::.
XP_011 GPFYVPESFF-EGGYPAYASGGGYVIAGRLAPWLLRAAARVAPFPFEDVYTGLCIRALGL
290 300 310 320 330 340
340 350 360 370 380 390
pF1KE0 QPTAHEGFKTFGISRNRNSRMNKEPCFFRAMLVVHKLLPPELLAMWGLVHS-NLTCSRKL
: :: :: : . .:.. . : :: .:.:. : : . .: ... : :
XP_011 VPQAHPGFLT-AWPADRTA----DHCAFRNLLLVRPLGPQASIRLWKQLQDPRLQC
350 360 370 380 390
400
pF1KE0 QVL
401 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 23:29:25 2016 done: Wed Nov 2 23:29:26 2016
Total Scan time: 8.790 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]