Result of FASTA (omim) for
pF1KE0540
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0540, 266 aa
1>>>pF1KE0540 266 - 266 aa - 266 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2298+/-0.00027; mu= 16.7013+/- 0.017
mean_var=80.5710+/-16.488, 0's: 0 Z-trim(120.3): 7 B-trim: 58 in 1/56
Lambda= 0.142884
statistics sampled from 35313 (35320) to 35313 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.774), E-opt: 0.2 (0.414), width: 16
Scan time: 6.600
The best scores are: opt bits E(85289)
NP_001162581 (OMIM: 604272,604377,608908) protein ( 266) 1807 381.2 1e-105
NP_001162580 (OMIM: 604272,604377,608908) protein ( 266) 1807 381.2 1e-105
NP_001162582 (OMIM: 604272,604377,608908) protein ( 266) 1807 381.2 1e-105
NP_005129 (OMIM: 604272,604377,608908) protein SCO ( 266) 1807 381.2 1e-105
NP_004580 (OMIM: 220110,603644) protein SCO1 homol ( 301) 712 155.6 1e-37
XP_005256808 (OMIM: 220110,603644) PREDICTED: prot ( 190) 672 147.2 2.2e-35
>>NP_001162581 (OMIM: 604272,604377,608908) protein SCO2 (266 aa)
initn: 1807 init1: 1807 opt: 1807 Z-score: 2018.9 bits: 381.2 E(85289): 1e-105
Smith-Waterman score: 1807; 99.6% identity (99.6% similar) in 266 aa overlap (1-266:1-266)
10 20 30 40 50 60
pF1KE0 MLLLTRSPTAWHRLSQLKPPVLPGTLGGQALHLRSWLLSRQGPAETGGQGQPQGPGLRTR
::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
NP_001 MLLLTRSPTAWHRLSQLKPRVLPGTLGGQALHLRSWLLSRQGPAETGGQGQPQGPGLRTR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 LLITGLFGAGLGGAWLALRAEKERLQQQKRTEALRQAAVGQGDFHLLDHRGRARCKADFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLITGLFGAGLGGAWLALRAEKERLQQQKRTEALRQAAVGQGDFHLLDHRGRARCKADFR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 GQWVLMYFGFTHCPDICPDELEKLVQVVRQLEAEPGLPPVQPVFITVDPERDDVEAMARY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQWVLMYFGFTHCPDICPDELEKLVQVVRQLEAEPGLPPVQPVFITVDPERDDVEAMARY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 VQDFHPRLLGLTGSTKQVAQASHSYRVYYNAGPKDEDQDYIVDHSIAIYLLNPDGLFTDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQDFHPRLLGLTGSTKQVAQASHSYRVYYNAGPKDEDQDYIVDHSIAIYLLNPDGLFTDY
190 200 210 220 230 240
250 260
pF1KE0 YGRSRSAEQISDSVRRHMAAFRSVLS
::::::::::::::::::::::::::
NP_001 YGRSRSAEQISDSVRRHMAAFRSVLS
250 260
>>NP_001162580 (OMIM: 604272,604377,608908) protein SCO2 (266 aa)
initn: 1807 init1: 1807 opt: 1807 Z-score: 2018.9 bits: 381.2 E(85289): 1e-105
Smith-Waterman score: 1807; 99.6% identity (99.6% similar) in 266 aa overlap (1-266:1-266)
10 20 30 40 50 60
pF1KE0 MLLLTRSPTAWHRLSQLKPPVLPGTLGGQALHLRSWLLSRQGPAETGGQGQPQGPGLRTR
::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
NP_001 MLLLTRSPTAWHRLSQLKPRVLPGTLGGQALHLRSWLLSRQGPAETGGQGQPQGPGLRTR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 LLITGLFGAGLGGAWLALRAEKERLQQQKRTEALRQAAVGQGDFHLLDHRGRARCKADFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLITGLFGAGLGGAWLALRAEKERLQQQKRTEALRQAAVGQGDFHLLDHRGRARCKADFR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 GQWVLMYFGFTHCPDICPDELEKLVQVVRQLEAEPGLPPVQPVFITVDPERDDVEAMARY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQWVLMYFGFTHCPDICPDELEKLVQVVRQLEAEPGLPPVQPVFITVDPERDDVEAMARY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 VQDFHPRLLGLTGSTKQVAQASHSYRVYYNAGPKDEDQDYIVDHSIAIYLLNPDGLFTDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQDFHPRLLGLTGSTKQVAQASHSYRVYYNAGPKDEDQDYIVDHSIAIYLLNPDGLFTDY
190 200 210 220 230 240
250 260
pF1KE0 YGRSRSAEQISDSVRRHMAAFRSVLS
::::::::::::::::::::::::::
NP_001 YGRSRSAEQISDSVRRHMAAFRSVLS
250 260
>>NP_001162582 (OMIM: 604272,604377,608908) protein SCO2 (266 aa)
initn: 1807 init1: 1807 opt: 1807 Z-score: 2018.9 bits: 381.2 E(85289): 1e-105
Smith-Waterman score: 1807; 99.6% identity (99.6% similar) in 266 aa overlap (1-266:1-266)
10 20 30 40 50 60
pF1KE0 MLLLTRSPTAWHRLSQLKPPVLPGTLGGQALHLRSWLLSRQGPAETGGQGQPQGPGLRTR
::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
NP_001 MLLLTRSPTAWHRLSQLKPRVLPGTLGGQALHLRSWLLSRQGPAETGGQGQPQGPGLRTR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 LLITGLFGAGLGGAWLALRAEKERLQQQKRTEALRQAAVGQGDFHLLDHRGRARCKADFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLITGLFGAGLGGAWLALRAEKERLQQQKRTEALRQAAVGQGDFHLLDHRGRARCKADFR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 GQWVLMYFGFTHCPDICPDELEKLVQVVRQLEAEPGLPPVQPVFITVDPERDDVEAMARY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQWVLMYFGFTHCPDICPDELEKLVQVVRQLEAEPGLPPVQPVFITVDPERDDVEAMARY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 VQDFHPRLLGLTGSTKQVAQASHSYRVYYNAGPKDEDQDYIVDHSIAIYLLNPDGLFTDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQDFHPRLLGLTGSTKQVAQASHSYRVYYNAGPKDEDQDYIVDHSIAIYLLNPDGLFTDY
190 200 210 220 230 240
250 260
pF1KE0 YGRSRSAEQISDSVRRHMAAFRSVLS
::::::::::::::::::::::::::
NP_001 YGRSRSAEQISDSVRRHMAAFRSVLS
250 260
>>NP_005129 (OMIM: 604272,604377,608908) protein SCO2 ho (266 aa)
initn: 1807 init1: 1807 opt: 1807 Z-score: 2018.9 bits: 381.2 E(85289): 1e-105
Smith-Waterman score: 1807; 99.6% identity (99.6% similar) in 266 aa overlap (1-266:1-266)
10 20 30 40 50 60
pF1KE0 MLLLTRSPTAWHRLSQLKPPVLPGTLGGQALHLRSWLLSRQGPAETGGQGQPQGPGLRTR
::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
NP_005 MLLLTRSPTAWHRLSQLKPRVLPGTLGGQALHLRSWLLSRQGPAETGGQGQPQGPGLRTR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 LLITGLFGAGLGGAWLALRAEKERLQQQKRTEALRQAAVGQGDFHLLDHRGRARCKADFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LLITGLFGAGLGGAWLALRAEKERLQQQKRTEALRQAAVGQGDFHLLDHRGRARCKADFR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 GQWVLMYFGFTHCPDICPDELEKLVQVVRQLEAEPGLPPVQPVFITVDPERDDVEAMARY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GQWVLMYFGFTHCPDICPDELEKLVQVVRQLEAEPGLPPVQPVFITVDPERDDVEAMARY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 VQDFHPRLLGLTGSTKQVAQASHSYRVYYNAGPKDEDQDYIVDHSIAIYLLNPDGLFTDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VQDFHPRLLGLTGSTKQVAQASHSYRVYYNAGPKDEDQDYIVDHSIAIYLLNPDGLFTDY
190 200 210 220 230 240
250 260
pF1KE0 YGRSRSAEQISDSVRRHMAAFRSVLS
::::::::::::::::::::::::::
NP_005 YGRSRSAEQISDSVRRHMAAFRSVLS
250 260
>>NP_004580 (OMIM: 220110,603644) protein SCO1 homolog, (301 aa)
initn: 667 init1: 617 opt: 712 Z-score: 798.2 bits: 155.6 E(85289): 1e-37
Smith-Waterman score: 712; 44.1% identity (72.7% similar) in 227 aa overlap (36-262:76-298)
10 20 30 40 50 60
pF1KE0 RSPTAWHRLSQLKPPVLPGTLGGQALHLRSWLLSRQGPAETGGQGQPQGPGLRTRLLITG
: :..::... ..: :: : ::
NP_004 ARQAEAWRASGRPGYCLGTRPLSTARPPPPW--SQKGPGDSTRPSKP-GPVSWKSLAITF
50 60 70 80 90 100
70 80 90 100 110 120
pF1KE0 LFGAGLGGAWLALRAEKERLQQQKRTEALRQAAVGQGDFHLLDHRGRARCKADFRGQWVL
.:..: .. .. :: . ...: . . . .: : : : : :. . :. :::.:
NP_004 AIGGALLAGMKHVKKEKAEKLEKERQRHIGKPLLG-GPFSLTTHTGERKTDKDYLGQWLL
110 120 130 140 150 160
130 140 150 160 170 180
pF1KE0 MYFGFTHCPDICPDELEKLVQVVRQLEAEPGLPPVQPVFITVDPERDDVEAMARYVQDFH
.:::::::::.::.::::..::: .... :: . :.::..::::: ::.: ::..:
NP_004 IYFGFTHCPDVCPEELEKMIQVVDEIDSITTLPDLTPLFISIDPERDTKEAIANYVKEFS
170 180 190 200 210 220
190 200 210 220 230 240
pF1KE0 PRLLGLTGSTKQVAQASHSYRVYYNAGPKDEDQDYIVDHSIAIYLLNPDGLFTDYYGRSR
:.:.::::. ..: :....:::::. ::::::.::::::.: .::..::: : ::.:...
NP_004 PKLVGLTGTREEVDQVARAYRVYYSPGPKDEDEDYIVDHTIIMYLIGPDGEFLDYFGQNK
230 240 250 260 270 280
250 260
pF1KE0 SAEQISDSVRRHMAAFRSVLS
.:. :. :: .:
NP_004 RKGEIAASIATHMRPYRKKS
290 300
>>XP_005256808 (OMIM: 220110,603644) PREDICTED: protein (190 aa)
initn: 651 init1: 617 opt: 672 Z-score: 756.3 bits: 147.2 E(85289): 2.2e-35
Smith-Waterman score: 672; 48.6% identity (75.7% similar) in 181 aa overlap (86-262:7-187)
60 70 80 90 100 110
pF1KE0 GLRTRLLITGLFGAGLGGAWLALRAEKERLQQQKRTEALRQAAVGQ----GDFHLLDHRG
.. .. : :: .:. : : : : :
XP_005 MKHVKKEKAEKLEKERQRHIGKPLLGGPFSLTTHTG
10 20 30
120 130 140 150 160 170
pF1KE0 RARCKADFRGQWVLMYFGFTHCPDICPDELEKLVQVVRQLEAEPGLPPVQPVFITVDPER
. . :. :::.:.:::::::::.::.::::..::: .... :: . :.::..::::
XP_005 ERKTDKDYLGQWLLIYFGFTHCPDVCPEELEKMIQVVDEIDSITTLPDLTPLFISIDPER
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE0 DDVEAMARYVQDFHPRLLGLTGSTKQVAQASHSYRVYYNAGPKDEDQDYIVDHSIAIYLL
: ::.: ::..: :.:.::::. ..: :....:::::. ::::::.::::::.: .::.
XP_005 DTKEAIANYVKEFSPKLVGLTGTREEVDQVARAYRVYYSPGPKDEDEDYIVDHTIIMYLI
100 110 120 130 140 150
240 250 260
pF1KE0 NPDGLFTDYYGRSRSAEQISDSVRRHMAAFRSVLS
.::: : ::.:... .:. :. :: .:
XP_005 GPDGEFLDYFGQNKRKGEIAASIATHMRPYRKKS
160 170 180 190
266 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 00:27:32 2016 done: Thu Nov 3 00:27:33 2016
Total Scan time: 6.600 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]