Result of FASTA (omim) for
pF1KE0537
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0537, 262 aa
1>>>pF1KE0537 262 - 262 aa - 262 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1791+/-0.000356; mu= 15.2236+/- 0.022
mean_var=59.7067+/-11.908, 0's: 0 Z-trim(112.9): 21 B-trim: 0 in 0/53
Lambda= 0.165983
statistics sampled from 21954 (21963) to 21954 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.636), E-opt: 0.2 (0.258), width: 16
Scan time: 4.430
The best scores are: opt bits E(85289)
NP_002667 (OMIM: 601786) phosphomannomutase 1 [Hom ( 262) 1753 428.1 8e-120
XP_011528532 (OMIM: 601786) PREDICTED: phosphomann ( 267) 1569 384.0 1.5e-106
NP_000294 (OMIM: 212065,601785) phosphomannomutase ( 246) 1144 282.2 6e-76
XP_011528534 (OMIM: 601786) PREDICTED: phosphomann ( 165) 938 232.8 3e-61
XP_005261695 (OMIM: 601786) PREDICTED: phosphomann ( 165) 938 232.8 3e-61
XP_011528533 (OMIM: 601786) PREDICTED: phosphomann ( 192) 938 232.9 3.4e-61
XP_011528531 (OMIM: 601786) PREDICTED: phosphomann ( 305) 938 233.0 5.1e-61
XP_005255431 (OMIM: 212065,601785) PREDICTED: phos ( 163) 800 199.8 2.6e-51
>>NP_002667 (OMIM: 601786) phosphomannomutase 1 [Homo sa (262 aa)
initn: 1753 init1: 1753 opt: 1753 Z-score: 2272.2 bits: 428.1 E(85289): 8e-120
Smith-Waterman score: 1753; 100.0% identity (100.0% similar) in 262 aa overlap (1-262:1-262)
10 20 30 40 50 60
pF1KE0 MAVTAQAARRKERVLCLFDVDGTLTPARQKIDPEVAAFLQKLRSRVQIGVVGGSDYCKIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAVTAQAARRKERVLCLFDVDGTLTPARQKIDPEVAAFLQKLRSRVQIGVVGGSDYCKIA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 EQLGDGDEVIEKFDYVFAENGTVQYKHGRLLSKQTIQNHLGEELLQDLINFCLSYMALLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EQLGDGDEVIEKFDYVFAENGTVQYKHGRLLSKQTIQNHLGEELLQDLINFCLSYMALLR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LPKKRGTFIEFRNGMLNISPIGRSCTLEERIEFSELDKKEKIREKFVEALKTEFAGKGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LPKKRGTFIEFRNGMLNISPIGRSCTLEERIEFSELDKKEKIREKFVEALKTEFAGKGLR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 FSRGGMISFDVFPEGWDKRYCLDSLDQDSFDTIHFFGNETSPGGNDFEIFADPRTVGHSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FSRGGMISFDVFPEGWDKRYCLDSLDQDSFDTIHFFGNETSPGGNDFEIFADPRTVGHSV
190 200 210 220 230 240
250 260
pF1KE0 VSPQDTVQRCREIFFPETAHEA
::::::::::::::::::::::
NP_002 VSPQDTVQRCREIFFPETAHEA
250 260
>>XP_011528532 (OMIM: 601786) PREDICTED: phosphomannomut (267 aa)
initn: 1569 init1: 1569 opt: 1569 Z-score: 2034.0 bits: 384.0 E(85289): 1.5e-106
Smith-Waterman score: 1569; 99.6% identity (100.0% similar) in 234 aa overlap (29-262:34-267)
10 20 30 40 50
pF1KE0 MAVTAQAARRKERVLCLFDVDGTLTPARQKIDPEVAAFLQKLRSRVQIGVVGGSDYCK
.:::::::::::::::::::::::::::::
XP_011 PILCGEVALAWALEAFLQGWIREEDSRTGAKKIDPEVAAFLQKLRSRVQIGVVGGSDYCK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 IAEQLGDGDEVIEKFDYVFAENGTVQYKHGRLLSKQTIQNHLGEELLQDLINFCLSYMAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAEQLGDGDEVIEKFDYVFAENGTVQYKHGRLLSKQTIQNHLGEELLQDLINFCLSYMAL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 LRLPKKRGTFIEFRNGMLNISPIGRSCTLEERIEFSELDKKEKIREKFVEALKTEFAGKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRLPKKRGTFIEFRNGMLNISPIGRSCTLEERIEFSELDKKEKIREKFVEALKTEFAGKG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 LRFSRGGMISFDVFPEGWDKRYCLDSLDQDSFDTIHFFGNETSPGGNDFEIFADPRTVGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRFSRGGMISFDVFPEGWDKRYCLDSLDQDSFDTIHFFGNETSPGGNDFEIFADPRTVGH
190 200 210 220 230 240
240 250 260
pF1KE0 SVVSPQDTVQRCREIFFPETAHEA
::::::::::::::::::::::::
XP_011 SVVSPQDTVQRCREIFFPETAHEA
250 260
>>NP_000294 (OMIM: 212065,601785) phosphomannomutase 2 [ (246 aa)
initn: 938 init1: 918 opt: 1144 Z-score: 1484.5 bits: 282.2 E(85289): 6e-76
Smith-Waterman score: 1144; 68.3% identity (86.7% similar) in 240 aa overlap (15-254:8-245)
10 20 30 40 50 60
pF1KE0 MAVTAQAARRKERVLCLFDVDGTLTPARQKIDPEVAAFLQKLRSRVQIGVVGGSDYCKIA
::::::::::: :::: :. ::::::....::::::::. :.
NP_000 MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQ
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 EQLGDGDEVIEKFDYVFAENGTVQYKHGRLLSKQTIQNHLGEELLQDLINFCLSYMALLR
:::: ..:.::.:::: ::: : :: :.:: .:.::.:::: :.:::::.::::.: ..
NP_000 EQLG--NDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 LPKKRGTFIEFRNGMLNISPIGRSCTLEERIEFSELDKKEKIREKFVEALKTEFAGKGLR
:::::::::::::::::.:::::::. :::::: ::::::.::.::: :. :::::::
NP_000 LPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLT
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 FSRGGMISFDVFPEGWDKRYCLDSLDQDSFDTIHFFGNETSPGGNDFEIFADPRTVGHSV
:: ::.:::::::.:::::::: ...:.. ::.:::..: ::::: :::.::::.:.::
NP_000 FSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSV
180 190 200 210 220 230
250 260
pF1KE0 VSPQDTVQRCREIFFPETAHEA
..:.:: . :. .:
NP_000 TAPEDTRRICELLFS
240
>>XP_011528534 (OMIM: 601786) PREDICTED: phosphomannomut (165 aa)
initn: 938 init1: 938 opt: 938 Z-score: 1220.6 bits: 232.8 E(85289): 3e-61
Smith-Waterman score: 938; 100.0% identity (100.0% similar) in 137 aa overlap (126-262:29-165)
100 110 120 130 140 150
pF1KE0 IQNHLGEELLQDLINFCLSYMALLRLPKKRGTFIEFRNGMLNISPIGRSCTLEERIEFSE
::::::::::::::::::::::::::::::
XP_011 MKSLRSLIMCLPRTGRCSISTDDCSPSSGTFIEFRNGMLNISPIGRSCTLEERIEFSE
10 20 30 40 50
160 170 180 190 200 210
pF1KE0 LDKKEKIREKFVEALKTEFAGKGLRFSRGGMISFDVFPEGWDKRYCLDSLDQDSFDTIHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDKKEKIREKFVEALKTEFAGKGLRFSRGGMISFDVFPEGWDKRYCLDSLDQDSFDTIHF
60 70 80 90 100 110
220 230 240 250 260
pF1KE0 FGNETSPGGNDFEIFADPRTVGHSVVSPQDTVQRCREIFFPETAHEA
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGNETSPGGNDFEIFADPRTVGHSVVSPQDTVQRCREIFFPETAHEA
120 130 140 150 160
>>XP_005261695 (OMIM: 601786) PREDICTED: phosphomannomut (165 aa)
initn: 938 init1: 938 opt: 938 Z-score: 1220.6 bits: 232.8 E(85289): 3e-61
Smith-Waterman score: 938; 100.0% identity (100.0% similar) in 137 aa overlap (126-262:29-165)
100 110 120 130 140 150
pF1KE0 IQNHLGEELLQDLINFCLSYMALLRLPKKRGTFIEFRNGMLNISPIGRSCTLEERIEFSE
::::::::::::::::::::::::::::::
XP_005 MKSLRSLIMCLPRTGRCSISTDDCSPSSGTFIEFRNGMLNISPIGRSCTLEERIEFSE
10 20 30 40 50
160 170 180 190 200 210
pF1KE0 LDKKEKIREKFVEALKTEFAGKGLRFSRGGMISFDVFPEGWDKRYCLDSLDQDSFDTIHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDKKEKIREKFVEALKTEFAGKGLRFSRGGMISFDVFPEGWDKRYCLDSLDQDSFDTIHF
60 70 80 90 100 110
220 230 240 250 260
pF1KE0 FGNETSPGGNDFEIFADPRTVGHSVVSPQDTVQRCREIFFPETAHEA
:::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FGNETSPGGNDFEIFADPRTVGHSVVSPQDTVQRCREIFFPETAHEA
120 130 140 150 160
>>XP_011528533 (OMIM: 601786) PREDICTED: phosphomannomut (192 aa)
initn: 1112 init1: 938 opt: 938 Z-score: 1219.6 bits: 232.9 E(85289): 3.4e-61
Smith-Waterman score: 985; 66.4% identity (70.2% similar) in 262 aa overlap (1-262:1-192)
10 20 30 40 50 60
pF1KE0 MAVTAQAARRKERVLCLFDVDGTLTPARQKIDPEVAAFLQKLRSRVQIGVVGGSDYCKIA
:::::::::::::::::::::::::::::. ::: .. . . :.:.
XP_011 MAVTAQAARRKERVLCLFDVDGTLTPARQS-----------LRSLIM--CLPRTGRCSIS
10 20 30 40
70 80 90 100 110 120
pF1KE0 EQLGDGDEVIEKFDYVFAENGTVQYKHGRLLSKQTIQNHLGEELLQDLINFCLSYMALLR
:. :
XP_011 T-----DD-------------------------------------------CS-------
50
130 140 150 160 170 180
pF1KE0 LPKKRGTFIEFRNGMLNISPIGRSCTLEERIEFSELDKKEKIREKFVEALKTEFAGKGLR
:.. :::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 -PSS-GTFIEFRNGMLNISPIGRSCTLEERIEFSELDKKEKIREKFVEALKTEFAGKGLR
60 70 80 90 100 110
190 200 210 220 230 240
pF1KE0 FSRGGMISFDVFPEGWDKRYCLDSLDQDSFDTIHFFGNETSPGGNDFEIFADPRTVGHSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSRGGMISFDVFPEGWDKRYCLDSLDQDSFDTIHFFGNETSPGGNDFEIFADPRTVGHSV
120 130 140 150 160 170
250 260
pF1KE0 VSPQDTVQRCREIFFPETAHEA
::::::::::::::::::::::
XP_011 VSPQDTVQRCREIFFPETAHEA
180 190
>>XP_011528531 (OMIM: 601786) PREDICTED: phosphomannomut (305 aa)
initn: 1110 init1: 938 opt: 938 Z-score: 1216.5 bits: 233.0 E(85289): 5.1e-61
Smith-Waterman score: 960; 58.4% identity (69.6% similar) in 296 aa overlap (12-262:12-305)
10 20 30 40 50 60
pF1KE0 MAVTAQAARRKERVLCLFDVDGTLTPARQKIDPEVAAFLQKLRSRVQIGVVGGSDYCKIA
::::::::::::::::::. . : . : ... : .. : :. .
XP_011 MAVTAQAARRKERVLCLFDVDGTLTPARQSWSRE-GFFSNSFMSSTHPDVRGSRPSLFAV
10 20 30 40 50
70 80
pF1KE0 EQL--GDGDEV-----IEKFDYVFAENGTVQYKHGR------------------------
. : ..: : . :. .. . . ::
XP_011 RTLRNSEGPECPSPSSVVKLPWLGPWRPSCRGGSGRKIAGLEQRKLTLRWPPSCRSYEVE
60 70 80 90 100 110
90 100 110 120 130
pF1KE0 --------LLSKQTIQNHL-GEELLQDLINFCLSYMALLRLPK-----KRGTFIEFRNGM
: . ..... . : . :..:: .:: . . . ::::::::::
XP_011 CRSVWWAALTTVRSLSSWVTGMKSLRSLI-MCLPRTGRCSISTDDCSPSSGTFIEFRNGM
120 130 140 150 160 170
140 150 160 170 180 190
pF1KE0 LNISPIGRSCTLEERIEFSELDKKEKIREKFVEALKTEFAGKGLRFSRGGMISFDVFPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNISPIGRSCTLEERIEFSELDKKEKIREKFVEALKTEFAGKGLRFSRGGMISFDVFPEG
180 190 200 210 220 230
200 210 220 230 240 250
pF1KE0 WDKRYCLDSLDQDSFDTIHFFGNETSPGGNDFEIFADPRTVGHSVVSPQDTVQRCREIFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WDKRYCLDSLDQDSFDTIHFFGNETSPGGNDFEIFADPRTVGHSVVSPQDTVQRCREIFF
240 250 260 270 280 290
260
pF1KE0 PETAHEA
:::::::
XP_011 PETAHEA
300
>>XP_005255431 (OMIM: 212065,601785) PREDICTED: phosphom (163 aa)
initn: 786 init1: 786 opt: 800 Z-score: 1042.1 bits: 199.8 E(85289): 2.6e-51
Smith-Waterman score: 800; 70.4% identity (89.3% similar) in 159 aa overlap (96-254:4-162)
70 80 90 100 110 120
pF1KE0 GDEVIEKFDYVFAENGTVQYKHGRLLSKQTIQNHLGEELLQDLINFCLSYMALLRLPKKR
::.:::: :.:::::.::::.: ..:::::
XP_005 MMNIQSHLGEALIQDLINYCLSYIAKIKLPKKR
10 20 30
130 140 150 160 170 180
pF1KE0 GTFIEFRNGMLNISPIGRSCTLEERIEFSELDKKEKIREKFVEALKTEFAGKGLRFSRGG
::::::::::::.:::::::. :::::: ::::::.::.::: :. ::::::: :: ::
XP_005 GTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGG
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE0 MISFDVFPEGWDKRYCLDSLDQDSFDTIHFFGNETSPGGNDFEIFADPRTVGHSVVSPQD
.:::::::.:::::::: ...:.. ::.:::..: ::::: :::.::::.:.::..:.:
XP_005 QISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPED
100 110 120 130 140 150
250 260
pF1KE0 TVQRCREIFFPETAHEA
: . :. .:
XP_005 TRRICELLFS
160
262 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 00:33:40 2016 done: Thu Nov 3 00:33:40 2016
Total Scan time: 4.430 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]