Result of FASTA (ccds) for
pF1KE0493
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0493, 395 aa
1>>>pF1KE0493 395 - 395 aa - 395 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4812+/-0.000798; mu= 16.3748+/- 0.048
mean_var=72.9493+/-14.762, 0's: 0 Z-trim(108.7): 13 B-trim: 176 in 1/49
Lambda= 0.150163
statistics sampled from 10400 (10413) to 10400 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.701), E-opt: 0.2 (0.32), width: 16
Scan time: 3.060
The best scores are: opt bits E(32554)
CCDS14099.1 CHKB gene_id:1120|Hs108|chr22 ( 395) 2680 589.7 1.6e-168
CCDS8179.1 CHKA gene_id:1119|Hs108|chr11 ( 439) 1511 336.5 2.9e-92
CCDS8178.1 CHKA gene_id:1119|Hs108|chr11 ( 457) 1227 274.9 1e-73
CCDS8698.1 ETNK1 gene_id:55500|Hs108|chr12 ( 452) 419 99.9 5e-21
CCDS73006.1 ETNK2 gene_id:55224|Hs108|chr1 ( 394) 349 84.7 1.6e-16
>>CCDS14099.1 CHKB gene_id:1120|Hs108|chr22 (395 aa)
initn: 2680 init1: 2680 opt: 2680 Z-score: 3139.1 bits: 589.7 E(32554): 1.6e-168
Smith-Waterman score: 2680; 100.0% identity (100.0% similar) in 395 aa overlap (1-395:1-395)
10 20 30 40 50 60
pF1KE0 MAAEATAVAGSGAVGGCLAKDGLQQSKCPDTTPKRRRASSLSRDAERRAYQWCREYLGGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 MAAEATAVAGSGAVGGCLAKDGLQQSKCPDTTPKRRRASSLSRDAERRAYQWCREYLGGA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 WRRVQPEELRVYPVSGGLSNLLFRCSLPDHLPSVGEEPREVLLRLYGAILQGVDSLVLES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 WRRVQPEELRVYPVSGGLSNLLFRCSLPDHLPSVGEEPREVLLRLYGAILQGVDSLVLES
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 VMFAILAERSLGPQLYGVFPEGRLEQYIPSRPLKTQELREPVLSAAIATKMAQFHGMEMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 VMFAILAERSLGPQLYGVFPEGRLEQYIPSRPLKTQELREPVLSAAIATKMAQFHGMEMP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 FTKEPHWLFGTMERYLKQIQDLPPTGLPEMNLLEMYSLKDEMGNLRKLLESTPSPVVFCH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 FTKEPHWLFGTMERYLKQIQDLPPTGLPEMNLLEMYSLKDEMGNLRKLLESTPSPVVFCH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 NDIQEGNILLLSEPENADSLMLVDFEYSSYNYRGFDIGNHFCEWVYDYTHEEWPFYKARP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 NDIQEGNILLLSEPENADSLMLVDFEYSSYNYRGFDIGNHFCEWVYDYTHEEWPFYKARP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 TDYPTQEQQLHFIRHYLAEAKKGETLSQEEQRKLEEDLLVEVSRYALASHFFWGLWSILQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 TDYPTQEQQLHFIRHYLAEAKKGETLSQEEQRKLEEDLLVEVSRYALASHFFWGLWSILQ
310 320 330 340 350 360
370 380 390
pF1KE0 ASMSTIEFGYLDYAQSRFQFYFQQKGQLTSVHSSS
:::::::::::::::::::::::::::::::::::
CCDS14 ASMSTIEFGYLDYAQSRFQFYFQQKGQLTSVHSSS
370 380 390
>>CCDS8179.1 CHKA gene_id:1119|Hs108|chr11 (439 aa)
initn: 1327 init1: 448 opt: 1511 Z-score: 1769.8 bits: 336.5 E(32554): 2.9e-92
Smith-Waterman score: 1511; 60.8% identity (81.5% similar) in 367 aa overlap (29-388:74-437)
10 20 30 40 50
pF1KE0 MAAEATAVAGSGAVGGCLAKDGLQQSKCPDTTPKRRRASSLSRDAERRAYQWCREYLG
: : .. .: :::: ::.:.:
CCDS81 ESKQLGGQQPPLALPPPPPLPLPLPLPQPPPPQPPADEQPEPRTR---RRAYLWCKEFLP
50 60 70 80 90 100
60 70 80 90 100 110
pF1KE0 GAWRRVQPEELRVYPVSGGLSNLLFRCSLPDHLPSVGEEPREVLLRLYGAILQ-GVDSLV
:::: .. .:... . :::::.::.::::: ..:.:::.::::::::::: :....:
CCDS81 GAWRGLREDEFHISVIRGGLSNMLFQCSLPDTTATLGDEPRKVLLRLYGAILQMGAEAMV
110 120 130 140 150 160
120 130 140 150 160 170
pF1KE0 LESVMFAILAERSLGPQLYGVFPEGRLEQYIPSRPLKTQELREPVLSAAIATKMAQFHGM
::::::::::::::::.:::.::.:::::.:::: : :.:: : .:: :: ::: ::::
CCDS81 LESVMFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDTEELSLPDISAEIAEKMATFHGM
170 180 190 200 210 220
180 190 200 210 220 230
pF1KE0 EMPFTKEPHWLFGTMERYLKQIQDLPPTG---LPEMNLLEMYSLKDEMGNLRKLLESTPS
.:::.:::.:::::::.:::.. . : . ... : :.: :. :::.:::::::
CCDS81 KMPFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSYNLPLELENLRSLLESTPS
230 240 250 260 270 280
240 250 260 270 280 290
pF1KE0 PVVFCHNDIQEGNILLLSEPENADS--LMLVDFEYSSYNYRGFDIGNHFCEWVYDYTHEE
:::::::: :::::::: ::... :::.:::::::::::::::::::::.:::..:.
CCDS81 PVVFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYSYEK
290 300 310 320 330 340
300 310 320 330 340 350
pF1KE0 WPFYKARPTDYPTQEQQLHFIRHYLAEAKKG-ETLSQEEQRKLEEDLLVEVSRYALASHF
.::..: :::..:::::: :: .. :.:: ::. ..:..:.::.:.::::::
CCDS81 YPFFRANIRKYPTKKQQLHFISSYLPAFQNDFENLSTEEKSIIKEEMLLEVNRFALASHF
350 360 370 380 390 400
360 370 380 390
pF1KE0 FWGLWSILQASMSTIEFGYLDYAQSRFQFYFQQKGQLTSVHSSS
.::::::.::..:.:::::.::::.::. ::.:: .:
CCDS81 LWGLWSIVQAKISSIEFGYMDYAQARFDAYFHQKRKLGV
410 420 430
>>CCDS8178.1 CHKA gene_id:1119|Hs108|chr11 (457 aa)
initn: 1047 init1: 456 opt: 1227 Z-score: 1437.0 bits: 274.9 E(32554): 1e-73
Smith-Waterman score: 1475; 57.9% identity (77.7% similar) in 385 aa overlap (29-388:74-455)
10 20 30 40 50
pF1KE0 MAAEATAVAGSGAVGGCLAKDGLQQSKCPDTTPKRRRASSLSRDAERRAYQWCREYLG
: : .. .: :::: ::.:.:
CCDS81 ESKQLGGQQPPLALPPPPPLPLPLPLPQPPPPQPPADEQPEPRTR---RRAYLWCKEFLP
50 60 70 80 90 100
60 70 80 90 100 110
pF1KE0 GAWRRVQPEELRVYPVSGGLSNLLFRCSLPDHLPSVGEEPREVLLRLYGAILQ-------
:::: .. .:... . :::::.::.::::: ..:.:::.:::::::::::
CCDS81 GAWRGLREDEFHISVIRGGLSNMLFQCSLPDTTATLGDEPRKVLLRLYGAILQMRSCNKE
110 120 130 140 150 160
120 130 140 150
pF1KE0 ------------GVDSLVLESVMFAILAERSLGPQLYGVFPEGRLEQYIPSRPLKTQELR
:....:::::::::::::::::.:::.::.:::::.:::: : :.::
CCDS81 GSEQAQKENEFQGAEAMVLESVMFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDTEELS
170 180 190 200 210 220
160 170 180 190 200 210
pF1KE0 EPVLSAAIATKMAQFHGMEMPFTKEPHWLFGTMERYLKQIQDLPPTG---LPEMNLLEMY
: .:: :: ::: ::::.:::.:::.:::::::.:::.. . : . ... : :
CCDS81 LPDISAEIAEKMATFHGMKMPFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSY
230 240 250 260 270 280
220 230 240 250 260 270
pF1KE0 SLKDEMGNLRKLLESTPSPVVFCHNDIQEGNILLLSEPENADS--LMLVDFEYSSYNYRG
.: :. :::.::::::::::::::: :::::::: ::... :::.:::::::::::
CCDS81 NLPLELENLRSLLESTPSPVVFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRG
290 300 310 320 330 340
280 290 300 310 320 330
pF1KE0 FDIGNHFCEWVYDYTHEEWPFYKARPTDYPTQEQQLHFIRHYLAEAKKG-ETLSQEEQRK
::::::::::.:::..:..::..: :::..:::::: :: .. :.:: ::.
CCDS81 FDIGNHFCEWMYDYSYEKYPFFRANIRKYPTKKQQLHFISSYLPAFQNDFENLSTEEKSI
350 360 370 380 390 400
340 350 360 370 380 390
pF1KE0 LEEDLLVEVSRYALASHFFWGLWSILQASMSTIEFGYLDYAQSRFQFYFQQKGQLTSVHS
..:..:.::.:.::::::.::::::.::..:.:::::.::::.::. ::.:: .:
CCDS81 IKEEMLLEVNRFALASHFLWGLWSIVQAKISSIEFGYMDYAQARFDAYFHQKRKLGV
410 420 430 440 450
pF1KE0 SS
>>CCDS8698.1 ETNK1 gene_id:55500|Hs108|chr12 (452 aa)
initn: 527 init1: 266 opt: 419 Z-score: 491.1 bits: 99.9 E(32554): 5e-21
Smith-Waterman score: 555; 30.5% identity (59.0% similar) in 383 aa overlap (29-391:97-448)
10 20 30 40 50
pF1KE0 MAAEATAVAGSGAVGGCLAKDGLQQSKCPDTTPKRRRASSLSRDAERRAYQWCRE---
: .:. . . .: :. . :::
CCDS86 SAPAVLVVAVAVVVVVVSAVAWAMANYIHVPPGSPEVPKLNVTVQDQEE---HRCREGAL
70 80 90 100 110 120
60 70 80 90 100 110
pF1KE0 ----YLGGAWRRVQPEELRVYPVSGGLSNLLFRCSLPDHLPSVGEEPREVLLRLYGAILQ
.: : .:.:. . . :..: :. : . . . .: ::.:.:: .
CCDS86 SLLQHLRPHW---DPQEVTLQLFTDGITNKLIGCYVGNTMEDV------VLVRIYGNKTE
130 140 150 160 170
120 130 140 150 160 170
pF1KE0 GVDSLVLESVMFAILAERSLGPQLYGVFPEGRLEQYIPSRPLKTQELREPVLSAAIATKM
. . : : .: .. .:::: .: .: ..: .. : ... .:.. :: ..
CCDS86 LLVDRDEEVKSFRVLQAHGCAPQLYCTFNNGLCYEFIQGEALDPKHVCNPAIFRLIARQL
180 190 200 210 220 230
180 190 200 210 220
pF1KE0 AQFHGMEMP---FTKEPHWLFGTMERYLKQIQDLPPTGLPEMNLLEMYS--------LKD
:..:... . : :: : .:.. : :::. . .. . . :..
CCDS86 AKIHAIHAHNGWIPKSNLWL--KMGKYFSLI----PTGFADEDINKRFLSDIPSSQILQE
240 250 260 270 280
230 240 250 260 270 280
pF1KE0 EMGNLRKLLESTPSPVVFCHNDIQEGNILLLSEPENADSLMLVDFEYSSYNYRGFDIGNH
:: ....: . ::::.::::. ::. :. .....:.:::.::: ..:::::
CCDS86 EMTWMKEILSNLGSPVVLCHNDLLCKNIIY---NEKQGDVQFIDYEYSGYNYLAYDIGNH
290 300 310 320 330 340
290 300 310 320 330
pF1KE0 FCEW--VYDYTHEEWPFYKARPTDYPTQEQQLHFIRHYLAEAKKGETLSQEEQRKLEEDL
: :. : : . . :: .: : ...: :: :. . .. : .: : :
CCDS86 FNEFAGVSDVDY----------SLYPDRELQSQWLRAYLEAYKEFKGFGTEVTEKEVEIL
350 360 370 380 390
340 350 360 370 380 390
pF1KE0 LVEVSRYALASHFFWGLWSILQASMSTIEFGYLDYAQSRFQFYFQQKGQLTSVHSSS
...:...:::::::::::...::..::::: .: :: ::. ::..: ..:..
CCDS86 FIQVNQFALASHFFWGLWALIQAKYSTIEFDFLGYAIVRFNQYFKMKPEVTALKVPE
400 410 420 430 440 450
>>CCDS73006.1 ETNK2 gene_id:55224|Hs108|chr1 (394 aa)
initn: 365 init1: 125 opt: 349 Z-score: 410.0 bits: 84.7 E(32554): 1.6e-16
Smith-Waterman score: 392; 29.6% identity (56.9% similar) in 304 aa overlap (55-347:62-338)
30 40 50 60 70
pF1KE0 QSKCPDTTPKRRRASSLSRDAERRAYQWCREYLGGAWRRVQ-------PEELRVYPVSGG
. : :: : .: ::..:. . :
CCDS73 KAAASASCREPPGPPRAAAVAYFGISVDPDDILPGALRLIQELRPHWKPEQVRTKRFTDG
40 50 60 70 80 90
80 90 100 110 120 130
pF1KE0 LSNLLFRCSLPDHLPSVGEEPREVLLRLYGAILQGVDSLVLESVMFAILAERSLGPQLYG
..: : : . . . . ::.:.:: . . . : : .: .: .:.::
CCDS73 ITNKLVACYVEEDMQDC------VLVRVYGERTELLVDRENEVRNFQLLRAHSCAPKLYC
100 110 120 130 140
140 150 160 170 180 190
pF1KE0 VFPEGRLEQYIPSRPLKTQELREPVLSAAIATKMAQFHGMEMPFTKEPHWLFGTMERYLK
.: .: .:. . :. ...::: : :: .::..: .. . :. :. :.
CCDS73 TFQNGLCYEYMQGVALEPEHIREPRLFRLIALEMAKIHTIHANGSLPKPILWHKMHNYFT
150 160 170 180 190 200
200 210 220 230 240 250
pF1KE0 QIQD-LPPTGLPEMNLLEMYSLKDEMGNLRKLLESTPSPVVFCHNDIQEGNILLLSEPEN
... . :. .. .:. :. :.. :.. : . :::::::::. ::. :
CCDS73 LVKNEINPSLSADVPKVEV--LERELAWLKEHLSQLESPVVFCHNDLLCKNIIYDS---I
210 220 230 240 250 260
260 270 280 290 300 310
pF1KE0 ADSLMLVDFEYSSYNYRGFDIGNHFCEWVYDYTHEEWPFYKARPTDY---PTQEQQLHFI
. ..:.::..:::..::::::: : : . .:: :..: ::...
CCDS73 KGHVRFIDYEYAGYNYQAFDIGNHFNE-----------FAGVNEVDYCLYPARETQLQWL
270 280 290 300
320 330 340 350 360 370
pF1KE0 RHYLAEAKKGETLSQEEQRKLEEDLLVEVSRYALASHFFWGLWSILQASMSTIEFGYLDY
:: .:.:: ... .: .. : :.:...::
CCDS73 -HYYLQAQKGMAVTPREVQR----LYVQVNKFALGPSCVSSTMTASLQCCRVGNRHGEIA
310 320 330 340 350 360
380 390
pF1KE0 AQSRFQFYFQQKGQLTSVHSSS
CCDS73 RLTLSGLFPGVSLLLGSLGPHPEPVLHHRL
370 380 390
395 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 04:23:36 2016 done: Thu Nov 3 04:23:37 2016
Total Scan time: 3.060 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]