Result of FASTA (omim) for
pF1KE0478
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0478, 375 aa
1>>>pF1KE0478 375 - 375 aa - 375 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9740+/-0.000345; mu= 14.0259+/- 0.021
mean_var=94.2465+/-19.355, 0's: 0 Z-trim(116.3): 57 B-trim: 0 in 0/53
Lambda= 0.132112
statistics sampled from 27288 (27345) to 27288 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.694), E-opt: 0.2 (0.321), width: 16
Scan time: 8.910
The best scores are: opt bits E(85289)
NP_001035110 (OMIM: 158120) monocyte differentiati ( 375) 2497 486.1 5.7e-137
NP_000582 (OMIM: 158120) monocyte differentiation ( 375) 2497 486.1 5.7e-137
NP_001167576 (OMIM: 158120) monocyte differentiati ( 375) 2497 486.1 5.7e-137
NP_001167575 (OMIM: 158120) monocyte differentiati ( 375) 2497 486.1 5.7e-137
XP_016864065 (OMIM: 246300,603028,607948) PREDICTE ( 784) 169 42.6 0.0038
XP_011530518 (OMIM: 246300,603028,607948) PREDICTE ( 784) 169 42.6 0.0038
XP_016864063 (OMIM: 246300,603028,607948) PREDICTE ( 784) 169 42.6 0.0038
XP_016864062 (OMIM: 246300,603028,607948) PREDICTE ( 784) 169 42.6 0.0038
NP_001305724 (OMIM: 246300,603028,607948) toll-lik ( 784) 169 42.6 0.0038
NP_001305725 (OMIM: 246300,603028,607948) toll-lik ( 784) 169 42.6 0.0038
NP_001305716 (OMIM: 246300,603028,607948) toll-lik ( 784) 169 42.6 0.0038
NP_001305722 (OMIM: 246300,603028,607948) toll-lik ( 784) 169 42.6 0.0038
XP_016864064 (OMIM: 246300,603028,607948) PREDICTE ( 784) 169 42.6 0.0038
NP_001305720 (OMIM: 246300,603028,607948) toll-lik ( 784) 169 42.6 0.0038
NP_003255 (OMIM: 246300,603028,607948) toll-like r ( 784) 169 42.6 0.0038
NP_001305718 (OMIM: 246300,603028,607948) toll-lik ( 784) 169 42.6 0.0038
XP_011530517 (OMIM: 246300,603028,607948) PREDICTE ( 784) 169 42.6 0.0038
NP_001305719 (OMIM: 246300,603028,607948) toll-lik ( 784) 169 42.6 0.0038
XP_011512045 (OMIM: 601194,613223) PREDICTED: toll ( 786) 164 41.6 0.0074
XP_011512044 (OMIM: 601194,613223) PREDICTED: toll ( 786) 164 41.6 0.0074
XP_005262719 (OMIM: 601194,613223) PREDICTED: toll ( 786) 164 41.6 0.0074
XP_011512047 (OMIM: 601194,613223) PREDICTED: toll ( 786) 164 41.6 0.0074
XP_011512046 (OMIM: 601194,613223) PREDICTED: toll ( 786) 164 41.6 0.0074
XP_016864060 (OMIM: 601194,613223) PREDICTED: toll ( 786) 164 41.6 0.0074
NP_003254 (OMIM: 601194,613223) toll-like receptor ( 786) 164 41.6 0.0074
XP_016864061 (OMIM: 601194,613223) PREDICTED: toll ( 786) 164 41.6 0.0074
>>NP_001035110 (OMIM: 158120) monocyte differentiation a (375 aa)
initn: 2497 init1: 2497 opt: 2497 Z-score: 2580.0 bits: 486.1 E(85289): 5.7e-137
Smith-Waterman score: 2497; 100.0% identity (100.0% similar) in 375 aa overlap (1-375:1-375)
10 20 30 40 50 60
pF1KE0 MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCVSAVEVEIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCVSAVEVEIH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AGGLNLEPFLKRVDADADPRQYADTVKALRVRRLTVGAAQVPAQLLVGALRVLAYSRLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGGLNLEPFLKRVDADADPRQYADTVKALRVRRLTVGAAQVPAQLLVGALRVLAYSRLKE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LTLEDLKITGTMPPLPLEATGLALSSLRLRNVSWATGRSWLAELQQWLKPGLKVLSIAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTLEDLKITGTMPPLPLEATGLALSSLRLRNVSWATGRSWLAELQQWLKPGLKVLSIAQA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 HSPAFSCEQVRAFPALTSLDLSDNPGLGERGLMAALCPHKFPAIQNLALRNTGMETPTGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSPAFSCEQVRAFPALTSLDLSDNPGLGERGLMAALCPHKFPAIQNLALRNTGMETPTGV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 CAALAAAGVQPHSLDLSHNSLRATVNPSAPRCMWSSALNSLNLSFAGLEQVPKGLPAKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CAALAAAGVQPHSLDLSHNSLRATVNPSAPRCMWSSALNSLNLSFAGLEQVPKGLPAKLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 VLDLSCNRLNRAPQPDELPEVDNLTLDGNPFLVPGTALPHEGSMNSGVVPACARSTLSVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLDLSCNRLNRAPQPDELPEVDNLTLDGNPFLVPGTALPHEGSMNSGVVPACARSTLSVG
310 320 330 340 350 360
370
pF1KE0 VSGTLVLLQGARGFA
:::::::::::::::
NP_001 VSGTLVLLQGARGFA
370
>>NP_000582 (OMIM: 158120) monocyte differentiation anti (375 aa)
initn: 2497 init1: 2497 opt: 2497 Z-score: 2580.0 bits: 486.1 E(85289): 5.7e-137
Smith-Waterman score: 2497; 100.0% identity (100.0% similar) in 375 aa overlap (1-375:1-375)
10 20 30 40 50 60
pF1KE0 MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCVSAVEVEIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCVSAVEVEIH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AGGLNLEPFLKRVDADADPRQYADTVKALRVRRLTVGAAQVPAQLLVGALRVLAYSRLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AGGLNLEPFLKRVDADADPRQYADTVKALRVRRLTVGAAQVPAQLLVGALRVLAYSRLKE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LTLEDLKITGTMPPLPLEATGLALSSLRLRNVSWATGRSWLAELQQWLKPGLKVLSIAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LTLEDLKITGTMPPLPLEATGLALSSLRLRNVSWATGRSWLAELQQWLKPGLKVLSIAQA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 HSPAFSCEQVRAFPALTSLDLSDNPGLGERGLMAALCPHKFPAIQNLALRNTGMETPTGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HSPAFSCEQVRAFPALTSLDLSDNPGLGERGLMAALCPHKFPAIQNLALRNTGMETPTGV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 CAALAAAGVQPHSLDLSHNSLRATVNPSAPRCMWSSALNSLNLSFAGLEQVPKGLPAKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CAALAAAGVQPHSLDLSHNSLRATVNPSAPRCMWSSALNSLNLSFAGLEQVPKGLPAKLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 VLDLSCNRLNRAPQPDELPEVDNLTLDGNPFLVPGTALPHEGSMNSGVVPACARSTLSVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VLDLSCNRLNRAPQPDELPEVDNLTLDGNPFLVPGTALPHEGSMNSGVVPACARSTLSVG
310 320 330 340 350 360
370
pF1KE0 VSGTLVLLQGARGFA
:::::::::::::::
NP_000 VSGTLVLLQGARGFA
370
>>NP_001167576 (OMIM: 158120) monocyte differentiation a (375 aa)
initn: 2497 init1: 2497 opt: 2497 Z-score: 2580.0 bits: 486.1 E(85289): 5.7e-137
Smith-Waterman score: 2497; 100.0% identity (100.0% similar) in 375 aa overlap (1-375:1-375)
10 20 30 40 50 60
pF1KE0 MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCVSAVEVEIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCVSAVEVEIH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AGGLNLEPFLKRVDADADPRQYADTVKALRVRRLTVGAAQVPAQLLVGALRVLAYSRLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGGLNLEPFLKRVDADADPRQYADTVKALRVRRLTVGAAQVPAQLLVGALRVLAYSRLKE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LTLEDLKITGTMPPLPLEATGLALSSLRLRNVSWATGRSWLAELQQWLKPGLKVLSIAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTLEDLKITGTMPPLPLEATGLALSSLRLRNVSWATGRSWLAELQQWLKPGLKVLSIAQA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 HSPAFSCEQVRAFPALTSLDLSDNPGLGERGLMAALCPHKFPAIQNLALRNTGMETPTGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSPAFSCEQVRAFPALTSLDLSDNPGLGERGLMAALCPHKFPAIQNLALRNTGMETPTGV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 CAALAAAGVQPHSLDLSHNSLRATVNPSAPRCMWSSALNSLNLSFAGLEQVPKGLPAKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CAALAAAGVQPHSLDLSHNSLRATVNPSAPRCMWSSALNSLNLSFAGLEQVPKGLPAKLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 VLDLSCNRLNRAPQPDELPEVDNLTLDGNPFLVPGTALPHEGSMNSGVVPACARSTLSVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLDLSCNRLNRAPQPDELPEVDNLTLDGNPFLVPGTALPHEGSMNSGVVPACARSTLSVG
310 320 330 340 350 360
370
pF1KE0 VSGTLVLLQGARGFA
:::::::::::::::
NP_001 VSGTLVLLQGARGFA
370
>>NP_001167575 (OMIM: 158120) monocyte differentiation a (375 aa)
initn: 2497 init1: 2497 opt: 2497 Z-score: 2580.0 bits: 486.1 E(85289): 5.7e-137
Smith-Waterman score: 2497; 100.0% identity (100.0% similar) in 375 aa overlap (1-375:1-375)
10 20 30 40 50 60
pF1KE0 MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCVSAVEVEIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCVSAVEVEIH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AGGLNLEPFLKRVDADADPRQYADTVKALRVRRLTVGAAQVPAQLLVGALRVLAYSRLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGGLNLEPFLKRVDADADPRQYADTVKALRVRRLTVGAAQVPAQLLVGALRVLAYSRLKE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LTLEDLKITGTMPPLPLEATGLALSSLRLRNVSWATGRSWLAELQQWLKPGLKVLSIAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTLEDLKITGTMPPLPLEATGLALSSLRLRNVSWATGRSWLAELQQWLKPGLKVLSIAQA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 HSPAFSCEQVRAFPALTSLDLSDNPGLGERGLMAALCPHKFPAIQNLALRNTGMETPTGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSPAFSCEQVRAFPALTSLDLSDNPGLGERGLMAALCPHKFPAIQNLALRNTGMETPTGV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 CAALAAAGVQPHSLDLSHNSLRATVNPSAPRCMWSSALNSLNLSFAGLEQVPKGLPAKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CAALAAAGVQPHSLDLSHNSLRATVNPSAPRCMWSSALNSLNLSFAGLEQVPKGLPAKLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 VLDLSCNRLNRAPQPDELPEVDNLTLDGNPFLVPGTALPHEGSMNSGVVPACARSTLSVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLDLSCNRLNRAPQPDELPEVDNLTLDGNPFLVPGTALPHEGSMNSGVVPACARSTLSVG
310 320 330 340 350 360
370
pF1KE0 VSGTLVLLQGARGFA
:::::::::::::::
NP_001 VSGTLVLLQGARGFA
370
>>XP_016864065 (OMIM: 246300,603028,607948) PREDICTED: t (784 aa)
initn: 97 init1: 97 opt: 169 Z-score: 177.5 bits: 42.6 E(85289): 0.0038
Smith-Waterman score: 170; 22.8% identity (51.8% similar) in 338 aa overlap (23-338:177-497)
10 20 30 40 50
pF1KE0 MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCV
: :.: :.. .: ...: :
XP_016 HLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELEIDASDLQSY------EPKSLKSIQNV
150 160 170 180 190 200
60 70 80 90 100
pF1KE0 SAVEVEIHAGGLNLEPF---------LKRVDADADPRQYADTVKALR---VRRLTVGAAQ
: . .... : :: : :. :.: : .... . ....: ..
XP_016 SHLILHMKQHILLLEIFVDVTSSVECLELRDTDLDTFHFSELSTGETNSLIKKFTFRNVK
210 220 230 240 250 260
110 120 130 140 150
pF1KE0 VPAQLLVGALRVLAY-SRLKELTLEDLKITGTMPPLPLEATGLA----LSSLRLRNVSWA
. . : ....: : : :: ..: ..:. . . . .: .: .
XP_016 ITDESLFQVMKLLNQISGLLELEFDDCTLNGVGNFRASDNDRVIDPGKVETLTIRRLH--
270 280 290 300 310
160 170 180 190 200 210
pF1KE0 TGRSWL-AELQQWLKPGLKVLSIAQAHSPAF--SCEQVRAFPALTSLDLSDNPGLGERGL
: .: .:. . .: :. .: .: : . . .: ::::.: . :. :
XP_016 IPRFYLFYDLSTLYSLTERVKRITVENSKVFLVPCLLSQHLKSLEYLDLSENL-MVEEYL
320 330 340 350 360 370
220 230 240 250 260 270
pF1KE0 MAALCPHKFPAIQNLALRNTGMETPTGVCAALAAAGVQPHSLDLSHNSLRATVNPSAPR-
. : .:..:.: ::.. . . . .: . . ..:.:.::.. : :.
XP_016 KNSACEDAWPSLQTLILRQNHLASLEKTGETLLTLK-NLTNIDISKNSFH-----SMPET
380 390 400 410 420 430
280 290 300 310 320 330
pF1KE0 CMWSSALNSLNLSFAGLEQVPKGLPAKLRVLDLSCNRLNRAPQPDELPEVDNLTLDGNPF
:.: .. :::: . ...: .: :..::.: : :: .::.. .: .. : .
XP_016 CQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNNLNLFSL--NLPQLKELYISRNKL
440 450 460 470 480
340 350 360 370
pF1KE0 L-VPGTALPHEGSMNSGVVPACARSTLSVGVSGTLVLLQGARGFA
. .: ..:
XP_016 MTLPDASLLPMLLVLKISRNAITTFSKEQLDSFHTLKTLEAGGNNFICSCEFLSFTQEQQ
490 500 510 520 530 540
>>XP_011530518 (OMIM: 246300,603028,607948) PREDICTED: t (784 aa)
initn: 97 init1: 97 opt: 169 Z-score: 177.5 bits: 42.6 E(85289): 0.0038
Smith-Waterman score: 170; 22.8% identity (51.8% similar) in 338 aa overlap (23-338:177-497)
10 20 30 40 50
pF1KE0 MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCV
: :.: :.. .: ...: :
XP_011 HLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELEIDASDLQSY------EPKSLKSIQNV
150 160 170 180 190 200
60 70 80 90 100
pF1KE0 SAVEVEIHAGGLNLEPF---------LKRVDADADPRQYADTVKALR---VRRLTVGAAQ
: . .... : :: : :. :.: : .... . ....: ..
XP_011 SHLILHMKQHILLLEIFVDVTSSVECLELRDTDLDTFHFSELSTGETNSLIKKFTFRNVK
210 220 230 240 250 260
110 120 130 140 150
pF1KE0 VPAQLLVGALRVLAY-SRLKELTLEDLKITGTMPPLPLEATGLA----LSSLRLRNVSWA
. . : ....: : : :: ..: ..:. . . . .: .: .
XP_011 ITDESLFQVMKLLNQISGLLELEFDDCTLNGVGNFRASDNDRVIDPGKVETLTIRRLH--
270 280 290 300 310
160 170 180 190 200 210
pF1KE0 TGRSWL-AELQQWLKPGLKVLSIAQAHSPAF--SCEQVRAFPALTSLDLSDNPGLGERGL
: .: .:. . .: :. .: .: : . . .: ::::.: . :. :
XP_011 IPRFYLFYDLSTLYSLTERVKRITVENSKVFLVPCLLSQHLKSLEYLDLSENL-MVEEYL
320 330 340 350 360 370
220 230 240 250 260 270
pF1KE0 MAALCPHKFPAIQNLALRNTGMETPTGVCAALAAAGVQPHSLDLSHNSLRATVNPSAPR-
. : .:..:.: ::.. . . . .: . . ..:.:.::.. : :.
XP_011 KNSACEDAWPSLQTLILRQNHLASLEKTGETLLTLK-NLTNIDISKNSFH-----SMPET
380 390 400 410 420 430
280 290 300 310 320 330
pF1KE0 CMWSSALNSLNLSFAGLEQVPKGLPAKLRVLDLSCNRLNRAPQPDELPEVDNLTLDGNPF
:.: .. :::: . ...: .: :..::.: : :: .::.. .: .. : .
XP_011 CQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNNLNLFSL--NLPQLKELYISRNKL
440 450 460 470 480
340 350 360 370
pF1KE0 L-VPGTALPHEGSMNSGVVPACARSTLSVGVSGTLVLLQGARGFA
. .: ..:
XP_011 MTLPDASLLPMLLVLKISRNAITTFSKEQLDSFHTLKTLEAGGNNFICSCEFLSFTQEQQ
490 500 510 520 530 540
>>XP_016864063 (OMIM: 246300,603028,607948) PREDICTED: t (784 aa)
initn: 97 init1: 97 opt: 169 Z-score: 177.5 bits: 42.6 E(85289): 0.0038
Smith-Waterman score: 170; 22.8% identity (51.8% similar) in 338 aa overlap (23-338:177-497)
10 20 30 40 50
pF1KE0 MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCV
: :.: :.. .: ...: :
XP_016 HLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELEIDASDLQSY------EPKSLKSIQNV
150 160 170 180 190 200
60 70 80 90 100
pF1KE0 SAVEVEIHAGGLNLEPF---------LKRVDADADPRQYADTVKALR---VRRLTVGAAQ
: . .... : :: : :. :.: : .... . ....: ..
XP_016 SHLILHMKQHILLLEIFVDVTSSVECLELRDTDLDTFHFSELSTGETNSLIKKFTFRNVK
210 220 230 240 250 260
110 120 130 140 150
pF1KE0 VPAQLLVGALRVLAY-SRLKELTLEDLKITGTMPPLPLEATGLA----LSSLRLRNVSWA
. . : ....: : : :: ..: ..:. . . . .: .: .
XP_016 ITDESLFQVMKLLNQISGLLELEFDDCTLNGVGNFRASDNDRVIDPGKVETLTIRRLH--
270 280 290 300 310
160 170 180 190 200 210
pF1KE0 TGRSWL-AELQQWLKPGLKVLSIAQAHSPAF--SCEQVRAFPALTSLDLSDNPGLGERGL
: .: .:. . .: :. .: .: : . . .: ::::.: . :. :
XP_016 IPRFYLFYDLSTLYSLTERVKRITVENSKVFLVPCLLSQHLKSLEYLDLSENL-MVEEYL
320 330 340 350 360 370
220 230 240 250 260 270
pF1KE0 MAALCPHKFPAIQNLALRNTGMETPTGVCAALAAAGVQPHSLDLSHNSLRATVNPSAPR-
. : .:..:.: ::.. . . . .: . . ..:.:.::.. : :.
XP_016 KNSACEDAWPSLQTLILRQNHLASLEKTGETLLTLK-NLTNIDISKNSFH-----SMPET
380 390 400 410 420 430
280 290 300 310 320 330
pF1KE0 CMWSSALNSLNLSFAGLEQVPKGLPAKLRVLDLSCNRLNRAPQPDELPEVDNLTLDGNPF
:.: .. :::: . ...: .: :..::.: : :: .::.. .: .. : .
XP_016 CQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNNLNLFSL--NLPQLKELYISRNKL
440 450 460 470 480
340 350 360 370
pF1KE0 L-VPGTALPHEGSMNSGVVPACARSTLSVGVSGTLVLLQGARGFA
. .: ..:
XP_016 MTLPDASLLPMLLVLKISRNAITTFSKEQLDSFHTLKTLEAGGNNFICSCEFLSFTQEQQ
490 500 510 520 530 540
>>XP_016864062 (OMIM: 246300,603028,607948) PREDICTED: t (784 aa)
initn: 97 init1: 97 opt: 169 Z-score: 177.5 bits: 42.6 E(85289): 0.0038
Smith-Waterman score: 170; 22.8% identity (51.8% similar) in 338 aa overlap (23-338:177-497)
10 20 30 40 50
pF1KE0 MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCV
: :.: :.. .: ...: :
XP_016 HLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELEIDASDLQSY------EPKSLKSIQNV
150 160 170 180 190 200
60 70 80 90 100
pF1KE0 SAVEVEIHAGGLNLEPF---------LKRVDADADPRQYADTVKALR---VRRLTVGAAQ
: . .... : :: : :. :.: : .... . ....: ..
XP_016 SHLILHMKQHILLLEIFVDVTSSVECLELRDTDLDTFHFSELSTGETNSLIKKFTFRNVK
210 220 230 240 250 260
110 120 130 140 150
pF1KE0 VPAQLLVGALRVLAY-SRLKELTLEDLKITGTMPPLPLEATGLA----LSSLRLRNVSWA
. . : ....: : : :: ..: ..:. . . . .: .: .
XP_016 ITDESLFQVMKLLNQISGLLELEFDDCTLNGVGNFRASDNDRVIDPGKVETLTIRRLH--
270 280 290 300 310
160 170 180 190 200 210
pF1KE0 TGRSWL-AELQQWLKPGLKVLSIAQAHSPAF--SCEQVRAFPALTSLDLSDNPGLGERGL
: .: .:. . .: :. .: .: : . . .: ::::.: . :. :
XP_016 IPRFYLFYDLSTLYSLTERVKRITVENSKVFLVPCLLSQHLKSLEYLDLSENL-MVEEYL
320 330 340 350 360 370
220 230 240 250 260 270
pF1KE0 MAALCPHKFPAIQNLALRNTGMETPTGVCAALAAAGVQPHSLDLSHNSLRATVNPSAPR-
. : .:..:.: ::.. . . . .: . . ..:.:.::.. : :.
XP_016 KNSACEDAWPSLQTLILRQNHLASLEKTGETLLTLK-NLTNIDISKNSFH-----SMPET
380 390 400 410 420 430
280 290 300 310 320 330
pF1KE0 CMWSSALNSLNLSFAGLEQVPKGLPAKLRVLDLSCNRLNRAPQPDELPEVDNLTLDGNPF
:.: .. :::: . ...: .: :..::.: : :: .::.. .: .. : .
XP_016 CQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNNLNLFSL--NLPQLKELYISRNKL
440 450 460 470 480
340 350 360 370
pF1KE0 L-VPGTALPHEGSMNSGVVPACARSTLSVGVSGTLVLLQGARGFA
. .: ..:
XP_016 MTLPDASLLPMLLVLKISRNAITTFSKEQLDSFHTLKTLEAGGNNFICSCEFLSFTQEQQ
490 500 510 520 530 540
>>NP_001305724 (OMIM: 246300,603028,607948) toll-like re (784 aa)
initn: 97 init1: 97 opt: 169 Z-score: 177.5 bits: 42.6 E(85289): 0.0038
Smith-Waterman score: 170; 22.8% identity (51.8% similar) in 338 aa overlap (23-338:177-497)
10 20 30 40 50
pF1KE0 MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCV
: :.: :.. .: ...: :
NP_001 HLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELEIDASDLQSY------EPKSLKSIQNV
150 160 170 180 190 200
60 70 80 90 100
pF1KE0 SAVEVEIHAGGLNLEPF---------LKRVDADADPRQYADTVKALR---VRRLTVGAAQ
: . .... : :: : :. :.: : .... . ....: ..
NP_001 SHLILHMKQHILLLEIFVDVTSSVECLELRDTDLDTFHFSELSTGETNSLIKKFTFRNVK
210 220 230 240 250 260
110 120 130 140 150
pF1KE0 VPAQLLVGALRVLAY-SRLKELTLEDLKITGTMPPLPLEATGLA----LSSLRLRNVSWA
. . : ....: : : :: ..: ..:. . . . .: .: .
NP_001 ITDESLFQVMKLLNQISGLLELEFDDCTLNGVGNFRASDNDRVIDPGKVETLTIRRLH--
270 280 290 300 310
160 170 180 190 200 210
pF1KE0 TGRSWL-AELQQWLKPGLKVLSIAQAHSPAF--SCEQVRAFPALTSLDLSDNPGLGERGL
: .: .:. . .: :. .: .: : . . .: ::::.: . :. :
NP_001 IPRFYLFYDLSTLYSLTERVKRITVENSKVFLVPCLLSQHLKSLEYLDLSENL-MVEEYL
320 330 340 350 360 370
220 230 240 250 260 270
pF1KE0 MAALCPHKFPAIQNLALRNTGMETPTGVCAALAAAGVQPHSLDLSHNSLRATVNPSAPR-
. : .:..:.: ::.. . . . .: . . ..:.:.::.. : :.
NP_001 KNSACEDAWPSLQTLILRQNHLASLEKTGETLLTLK-NLTNIDISKNSFH-----SMPET
380 390 400 410 420 430
280 290 300 310 320 330
pF1KE0 CMWSSALNSLNLSFAGLEQVPKGLPAKLRVLDLSCNRLNRAPQPDELPEVDNLTLDGNPF
:.: .. :::: . ...: .: :..::.: : :: .::.. .: .. : .
NP_001 CQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNNLNLFSL--NLPQLKELYISRNKL
440 450 460 470 480
340 350 360 370
pF1KE0 L-VPGTALPHEGSMNSGVVPACARSTLSVGVSGTLVLLQGARGFA
. .: ..:
NP_001 MTLPDASLLPMLLVLKISRNAITTFSKEQLDSFHTLKTLEAGGNNFICSCEFLSFTQEQQ
490 500 510 520 530 540
>>NP_001305725 (OMIM: 246300,603028,607948) toll-like re (784 aa)
initn: 97 init1: 97 opt: 169 Z-score: 177.5 bits: 42.6 E(85289): 0.0038
Smith-Waterman score: 170; 22.8% identity (51.8% similar) in 338 aa overlap (23-338:177-497)
10 20 30 40 50
pF1KE0 MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCV
: :.: :.. .: ...: :
NP_001 HLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELEIDASDLQSY------EPKSLKSIQNV
150 160 170 180 190 200
60 70 80 90 100
pF1KE0 SAVEVEIHAGGLNLEPF---------LKRVDADADPRQYADTVKALR---VRRLTVGAAQ
: . .... : :: : :. :.: : .... . ....: ..
NP_001 SHLILHMKQHILLLEIFVDVTSSVECLELRDTDLDTFHFSELSTGETNSLIKKFTFRNVK
210 220 230 240 250 260
110 120 130 140 150
pF1KE0 VPAQLLVGALRVLAY-SRLKELTLEDLKITGTMPPLPLEATGLA----LSSLRLRNVSWA
. . : ....: : : :: ..: ..:. . . . .: .: .
NP_001 ITDESLFQVMKLLNQISGLLELEFDDCTLNGVGNFRASDNDRVIDPGKVETLTIRRLH--
270 280 290 300 310
160 170 180 190 200 210
pF1KE0 TGRSWL-AELQQWLKPGLKVLSIAQAHSPAF--SCEQVRAFPALTSLDLSDNPGLGERGL
: .: .:. . .: :. .: .: : . . .: ::::.: . :. :
NP_001 IPRFYLFYDLSTLYSLTERVKRITVENSKVFLVPCLLSQHLKSLEYLDLSENL-MVEEYL
320 330 340 350 360 370
220 230 240 250 260 270
pF1KE0 MAALCPHKFPAIQNLALRNTGMETPTGVCAALAAAGVQPHSLDLSHNSLRATVNPSAPR-
. : .:..:.: ::.. . . . .: . . ..:.:.::.. : :.
NP_001 KNSACEDAWPSLQTLILRQNHLASLEKTGETLLTLK-NLTNIDISKNSFH-----SMPET
380 390 400 410 420 430
280 290 300 310 320 330
pF1KE0 CMWSSALNSLNLSFAGLEQVPKGLPAKLRVLDLSCNRLNRAPQPDELPEVDNLTLDGNPF
:.: .. :::: . ...: .: :..::.: : :: .::.. .: .. : .
NP_001 CQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNNLNLFSL--NLPQLKELYISRNKL
440 450 460 470 480
340 350 360 370
pF1KE0 L-VPGTALPHEGSMNSGVVPACARSTLSVGVSGTLVLLQGARGFA
. .: ..:
NP_001 MTLPDASLLPMLLVLKISRNAITTFSKEQLDSFHTLKTLEAGGNNFICSCEFLSFTQEQQ
490 500 510 520 530 540
375 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 05:16:40 2016 done: Thu Nov 3 05:16:41 2016
Total Scan time: 8.910 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]