Result of FASTA (omim) for
pF1KE0474
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0474, 167 aa
1>>>pF1KE0474 167 - 167 aa - 167 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2012+/-0.000321; mu= 12.5667+/- 0.020
mean_var=83.8939+/-17.201, 0's: 0 Z-trim(118.3): 210 B-trim: 539 in 2/48
Lambda= 0.140026
statistics sampled from 30816 (31130) to 30816 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.751), E-opt: 0.2 (0.365), width: 16
Scan time: 5.300
The best scores are: opt bits E(85289)
NP_536316 (OMIM: 601584) protein tyrosine phosphat ( 167) 1162 243.9 9.1e-65
XP_011534413 (OMIM: 601585) PREDICTED: protein tyr ( 173) 1044 220.1 1.4e-57
XP_011534414 (OMIM: 601585) PREDICTED: protein tyr ( 173) 1044 220.1 1.4e-57
NP_003454 (OMIM: 601585) protein tyrosine phosphat ( 173) 1044 220.1 1.4e-57
XP_016866760 (OMIM: 601585) PREDICTED: protein tyr ( 173) 1044 220.1 1.4e-57
XP_016866759 (OMIM: 601585) PREDICTED: protein tyr ( 173) 1044 220.1 1.4e-57
NP_116000 (OMIM: 606449) protein tyrosine phosphat ( 173) 927 196.4 1.8e-50
XP_011515107 (OMIM: 606449) PREDICTED: protein tyr ( 173) 927 196.4 1.8e-50
XP_005250821 (OMIM: 606449) PREDICTED: protein tyr ( 173) 927 196.4 1.8e-50
XP_011515105 (OMIM: 606449) PREDICTED: protein tyr ( 173) 927 196.4 1.8e-50
XP_016866761 (OMIM: 601585) PREDICTED: protein tyr ( 135) 819 174.5 5.7e-44
XP_006716563 (OMIM: 606449) PREDICTED: protein tyr ( 149) 753 161.2 6.3e-40
NP_001182029 (OMIM: 601584) protein tyrosine phosp ( 142) 752 161.0 7e-40
XP_005271288 (OMIM: 601584) PREDICTED: protein tyr ( 142) 752 161.0 7e-40
XP_016857890 (OMIM: 601584) PREDICTED: protein tyr ( 136) 751 160.8 7.8e-40
XP_005271289 (OMIM: 601584) PREDICTED: protein tyr ( 136) 751 160.8 7.8e-40
NP_001182030 (OMIM: 601584) protein tyrosine phosp ( 136) 751 160.8 7.8e-40
XP_016868487 (OMIM: 606449) PREDICTED: protein tyr ( 148) 602 130.7 9.5e-31
NP_009010 (OMIM: 606449) protein tyrosine phosphat ( 148) 602 130.7 9.5e-31
XP_016868488 (OMIM: 606449) PREDICTED: protein tyr ( 124) 428 95.5 3.2e-20
XP_016870738 (OMIM: 603505) PREDICTED: dual specif ( 296) 169 43.5 0.00034
XP_011517461 (OMIM: 603505) PREDICTED: dual specif ( 331) 169 43.5 0.00037
NP_201570 (OMIM: 603504,616958) dual specificity p ( 383) 169 43.6 0.00041
XP_016870737 (OMIM: 603505) PREDICTED: dual specif ( 390) 169 43.6 0.00041
XP_011540648 (OMIM: 603504,616958) PREDICTED: dual ( 392) 169 43.6 0.00042
XP_016870736 (OMIM: 603505) PREDICTED: dual specif ( 422) 169 43.6 0.00044
XP_016870735 (OMIM: 603505) PREDICTED: dual specif ( 448) 169 43.7 0.00046
XP_005252345 (OMIM: 603505) PREDICTED: dual specif ( 448) 169 43.7 0.00046
NP_003662 (OMIM: 603505) dual specificity protein ( 459) 169 43.7 0.00047
NP_001070649 (OMIM: 603505) dual specificity prote ( 461) 169 43.7 0.00047
XP_011517460 (OMIM: 603505) PREDICTED: dual specif ( 471) 169 43.7 0.00047
XP_016870734 (OMIM: 603505) PREDICTED: dual specif ( 479) 169 43.7 0.00048
XP_016870733 (OMIM: 603505) PREDICTED: dual specif ( 483) 169 43.7 0.00048
XP_016870732 (OMIM: 603505) PREDICTED: dual specif ( 485) 169 43.7 0.00048
XP_016858136 (OMIM: 603504,616958) PREDICTED: dual ( 489) 169 43.7 0.00049
XP_016858135 (OMIM: 603504,616958) PREDICTED: dual ( 490) 169 43.7 0.00049
XP_011540647 (OMIM: 603504,616958) PREDICTED: dual ( 495) 169 43.7 0.00049
NP_201588 (OMIM: 603505) dual specificity protein ( 498) 169 43.7 0.00049
XP_011517458 (OMIM: 603505) PREDICTED: dual specif ( 514) 169 43.7 0.00051
XP_016870731 (OMIM: 603505) PREDICTED: dual specif ( 520) 169 43.7 0.00051
XP_016870730 (OMIM: 603505) PREDICTED: dual specif ( 544) 169 43.7 0.00053
XP_011517455 (OMIM: 603505) PREDICTED: dual specif ( 552) 169 43.7 0.00053
XP_011517454 (OMIM: 603505) PREDICTED: dual specif ( 564) 169 43.8 0.00054
NP_001306140 (OMIM: 603504,616958) dual specificit ( 565) 169 43.8 0.00054
XP_011517452 (OMIM: 603505) PREDICTED: dual specif ( 578) 169 43.8 0.00055
XP_011517453 (OMIM: 603505) PREDICTED: dual specif ( 578) 169 43.8 0.00055
XP_011517451 (OMIM: 603505) PREDICTED: dual specif ( 585) 169 43.8 0.00056
XP_011517450 (OMIM: 603505) PREDICTED: dual specif ( 591) 169 43.8 0.00056
NP_003663 (OMIM: 603504,616958) dual specificity p ( 594) 169 43.8 0.00056
XP_005271353 (OMIM: 603504,616958) PREDICTED: dual ( 595) 169 43.8 0.00056
>>NP_536316 (OMIM: 601584) protein tyrosine phosphatase (167 aa)
initn: 1162 init1: 1162 opt: 1162 Z-score: 1283.7 bits: 243.9 E(85289): 9.1e-65
Smith-Waterman score: 1162; 100.0% identity (100.0% similar) in 167 aa overlap (1-167:1-167)
10 20 30 40 50 60
pF1KE0 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_536 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 HVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALIECG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_536 HVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALIECG
70 80 90 100 110 120
130 140 150 160
pF1KE0 MKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGHCCVQ
:::::::::::::::::::::::::::::::::::::::::::::::
NP_536 MKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGHCCVQ
130 140 150 160
>>XP_011534413 (OMIM: 601585) PREDICTED: protein tyrosin (173 aa)
initn: 1046 init1: 1023 opt: 1044 Z-score: 1154.7 bits: 220.1 E(85289): 1.4e-57
Smith-Waterman score: 1044; 87.6% identity (94.7% similar) in 170 aa overlap (1-167:4-173)
10 20 30 40 50
pF1KE0 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEK
::::::::..:.:::::::::::::::::: ::::::::::.::::.:::: . :::
XP_011 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 EGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALI
:::::::::::::::: ::::::::.:.: :::::::::.::::::::::::::::::::
XP_011 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI
70 80 90 100 110 120
120 130 140 150 160
pF1KE0 ECGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGH---CCVQ
: ::::::::::::::::::::::::::::::::::::::.:.::: ::.:
XP_011 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
130 140 150 160 170
>>XP_011534414 (OMIM: 601585) PREDICTED: protein tyrosin (173 aa)
initn: 1046 init1: 1023 opt: 1044 Z-score: 1154.7 bits: 220.1 E(85289): 1.4e-57
Smith-Waterman score: 1044; 87.6% identity (94.7% similar) in 170 aa overlap (1-167:4-173)
10 20 30 40 50
pF1KE0 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEK
::::::::..:.:::::::::::::::::: ::::::::::.::::.:::: . :::
XP_011 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 EGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALI
:::::::::::::::: ::::::::.:.: :::::::::.::::::::::::::::::::
XP_011 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI
70 80 90 100 110 120
120 130 140 150 160
pF1KE0 ECGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGH---CCVQ
: ::::::::::::::::::::::::::::::::::::::.:.::: ::.:
XP_011 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
130 140 150 160 170
>>NP_003454 (OMIM: 601585) protein tyrosine phosphatase (173 aa)
initn: 1046 init1: 1023 opt: 1044 Z-score: 1154.7 bits: 220.1 E(85289): 1.4e-57
Smith-Waterman score: 1044; 87.6% identity (94.7% similar) in 170 aa overlap (1-167:4-173)
10 20 30 40 50
pF1KE0 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEK
::::::::..:.:::::::::::::::::: ::::::::::.::::.:::: . :::
NP_003 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 EGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALI
:::::::::::::::: ::::::::.:.: :::::::::.::::::::::::::::::::
NP_003 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI
70 80 90 100 110 120
120 130 140 150 160
pF1KE0 ECGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGH---CCVQ
: ::::::::::::::::::::::::::::::::::::::.:.::: ::.:
NP_003 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
130 140 150 160 170
>>XP_016866760 (OMIM: 601585) PREDICTED: protein tyrosin (173 aa)
initn: 1046 init1: 1023 opt: 1044 Z-score: 1154.7 bits: 220.1 E(85289): 1.4e-57
Smith-Waterman score: 1044; 87.6% identity (94.7% similar) in 170 aa overlap (1-167:4-173)
10 20 30 40 50
pF1KE0 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEK
::::::::..:.:::::::::::::::::: ::::::::::.::::.:::: . :::
XP_016 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 EGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALI
:::::::::::::::: ::::::::.:.: :::::::::.::::::::::::::::::::
XP_016 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI
70 80 90 100 110 120
120 130 140 150 160
pF1KE0 ECGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGH---CCVQ
: ::::::::::::::::::::::::::::::::::::::.:.::: ::.:
XP_016 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
130 140 150 160 170
>>XP_016866759 (OMIM: 601585) PREDICTED: protein tyrosin (173 aa)
initn: 1046 init1: 1023 opt: 1044 Z-score: 1154.7 bits: 220.1 E(85289): 1.4e-57
Smith-Waterman score: 1044; 87.6% identity (94.7% similar) in 170 aa overlap (1-167:4-173)
10 20 30 40 50
pF1KE0 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEK
::::::::..:.:::::::::::::::::: ::::::::::.::::.:::: . :::
XP_016 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 EGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALI
:::::::::::::::: ::::::::.:.: :::::::::.::::::::::::::::::::
XP_016 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI
70 80 90 100 110 120
120 130 140 150 160
pF1KE0 ECGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGH---CCVQ
: ::::::::::::::::::::::::::::::::::::::.:.::: ::.:
XP_016 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
130 140 150 160 170
>>NP_116000 (OMIM: 606449) protein tyrosine phosphatase (173 aa)
initn: 929 init1: 912 opt: 927 Z-score: 1027.0 bits: 196.4 E(85289): 1.8e-50
Smith-Waterman score: 927; 77.5% identity (92.3% similar) in 169 aa overlap (1-166:4-172)
10 20 30 40 50
pF1KE0 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEK
::::::::.::..::::::::::::::. : :.:::::.::.::::..::::.:.::
NP_116 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 EGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALI
.:: :.:::::::::::...:.:::.:.:.:: : :: ::::::::::::::::::::::
NP_116 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI
70 80 90 100 110 120
120 130 140 150 160
pF1KE0 ECGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGH---CCVQ
: :::::::.::::::::::.::::: ::::::::.::::.: . : :::
NP_116 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
130 140 150 160 170
>>XP_011515107 (OMIM: 606449) PREDICTED: protein tyrosin (173 aa)
initn: 929 init1: 912 opt: 927 Z-score: 1027.0 bits: 196.4 E(85289): 1.8e-50
Smith-Waterman score: 927; 77.5% identity (92.3% similar) in 169 aa overlap (1-166:4-172)
10 20 30 40 50
pF1KE0 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEK
::::::::.::..::::::::::::::. : :.:::::.::.::::..::::.:.::
XP_011 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 EGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALI
.:: :.:::::::::::...:.:::.:.:.:: : :: ::::::::::::::::::::::
XP_011 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI
70 80 90 100 110 120
120 130 140 150 160
pF1KE0 ECGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGH---CCVQ
: :::::::.::::::::::.::::: ::::::::.::::.: . : :::
XP_011 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
130 140 150 160 170
>>XP_005250821 (OMIM: 606449) PREDICTED: protein tyrosin (173 aa)
initn: 929 init1: 912 opt: 927 Z-score: 1027.0 bits: 196.4 E(85289): 1.8e-50
Smith-Waterman score: 927; 77.5% identity (92.3% similar) in 169 aa overlap (1-166:4-172)
10 20 30 40 50
pF1KE0 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEK
::::::::.::..::::::::::::::. : :.:::::.::.::::..::::.:.::
XP_005 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 EGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALI
.:: :.:::::::::::...:.:::.:.:.:: : :: ::::::::::::::::::::::
XP_005 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI
70 80 90 100 110 120
120 130 140 150 160
pF1KE0 ECGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGH---CCVQ
: :::::::.::::::::::.::::: ::::::::.::::.: . : :::
XP_005 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
130 140 150 160 170
>>XP_011515105 (OMIM: 606449) PREDICTED: protein tyrosin (173 aa)
initn: 929 init1: 912 opt: 927 Z-score: 1027.0 bits: 196.4 E(85289): 1.8e-50
Smith-Waterman score: 927; 77.5% identity (92.3% similar) in 169 aa overlap (1-166:4-172)
10 20 30 40 50
pF1KE0 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEK
::::::::.::..::::::::::::::. : :.:::::.::.::::..::::.:.::
XP_011 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 EGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALI
.:: :.:::::::::::...:.:::.:.:.:: : :: ::::::::::::::::::::::
XP_011 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI
70 80 90 100 110 120
120 130 140 150 160
pF1KE0 ECGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGH---CCVQ
: :::::::.::::::::::.::::: ::::::::.::::.: . : :::
XP_011 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
130 140 150 160 170
167 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 05:56:04 2016 done: Thu Nov 3 05:56:05 2016
Total Scan time: 5.300 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]