FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0455, 226 aa
  1>>>pF1KE0455 226 - 226 aa - 226 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.4865+/-0.000294; mu= 18.1628+/- 0.018
 mean_var=54.3222+/-10.779, 0's: 0 Z-trim(116.7): 22  B-trim: 22 in 1/53
 Lambda= 0.174015
 statistics sampled from 28063 (28085) to 28063 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.688), E-opt: 0.2 (0.329), width:  16
 Scan time:  5.450

The best scores are:                                      opt bits E(85289)
NP_060877 (OMIM: 613296) lysosomal-associated tran ( 317) 1537 393.4 2.3e-109
XP_011540400 (OMIM: 601476) PREDICTED: lysosomal-a ( 205)  165 48.8   8e-06
NP_006753 (OMIM: 601476) lysosomal-associated tran ( 262)  165 48.9 9.7e-06


>>NP_060877 (OMIM: 613296) lysosomal-associated transmem  (317 aa)
 initn: 1537 init1: 1537 opt: 1537  Z-score: 2084.3  bits: 393.4 E(85289): 2.3e-109
Smith-Waterman score: 1537; 100.0% identity (100.0% similar) in 226 aa overlap (1-226:92-317)

                                             10        20        30
pF1KE0                               MKMVAPWTRFYSNSCCLCCHVRTGTILLGV
                                     ::::::::::::::::::::::::::::::
NP_060 SRQQRRGGLQARRSTLLKTCARARATAPGAMKMVAPWTRFYSNSCCLCCHVRTGTILLGV
              70        80        90       100       110       120 

               40        50        60        70        80        90
pF1KE0 WYLIINAVVLLILLSALADPDQYNFSSSELGGDFEFMDDANMCIAIAISLLMILICAMAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 WYLIINAVVLLILLSALADPDQYNFSSSELGGDFEFMDDANMCIAIAISLLMILICAMAT
             130       140       150       160       170       180 

              100       110       120       130       140       150
pF1KE0 YGAYKQRAAWIIPFFCYQIFDFALNMLVAITVLIYPNSIQEYIRQLPPNFPYRDDVMSVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 YGAYKQRAAWIIPFFCYQIFDFALNMLVAITVLIYPNSIQEYIRQLPPNFPYRDDVMSVN
             190       200       210       220       230       240 

              160       170       180       190       200       210
pF1KE0 PTCLVLIILLFISIILTFKGYLISCVWNCYRYINGRNSSDVLVYVTSNDTTVLLPPYDDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 PTCLVLIILLFISIILTFKGYLISCVWNCYRYINGRNSSDVLVYVTSNDTTVLLPPYDDA
             250       260       270       280       290       300 

              220      
pF1KE0 TVNGAAKEPPPPYVSA
       ::::::::::::::::
NP_060 TVNGAAKEPPPPYVSA
             310       

>>XP_011540400 (OMIM: 601476) PREDICTED: lysosomal-assoc  (205 aa)
 initn: 177 init1: 100 opt: 165  Z-score: 225.5  bits: 48.8 E(85289): 8e-06
Smith-Waterman score: 176; 26.2% identity (54.8% similar) in 168 aa overlap (76-223:39-202)

          50        60        70        80        90       100     
pF1KE0 ALADPDQYNFSSSELGGDFEFMDDANMCIAIAISLLMILICAMATYGAYKQRAAWI----
                                     ......  :.: ..  :.: .  :..    
XP_011 RQTCCCFNVRIATTALAIYHVNREKYLLPFLSLQIMDYLLCLLTLLGSYIELPAYLKLAS
       10        20        30        40        50        60        

                     110       120       130       140        150  
pF1KE0 --------IPFFCYQIFDFALNMLVAITVLIYPNSIQEYIRQLPPNF-PYRDDVMSVNPT
               .:..  :..:: :..:.  .  .   .  ..  .   :. : ..: :  :  
XP_011 RSRASSSKFPLMTLQLLDFCLSILTLCSSYMEVPTYLNFKSMNHMNYLPSQED-MPHNQF
       70        80        90       100       110       120        

              160       170       180       190       200       210
pF1KE0 CLVLII--LLFISIILTFKGYLISCVWNCYRYINGRNSSDVLVYVTSNDTTVLLPPYDDA
         ..::  . ::.. : :: :...::: ::: :.  :: .     ..    :.:: :..:
XP_011 IKMMIIFSIAFITV-LIFKVYMFKCVWRCYRLIKCMNSVEEK-RNSKMLQKVVLPSYEEA
       130       140        150       160        170       180     

                   220      
pF1KE0 TVNGAAKEP-----PPPYVSA
        ..  .: :     ::::   
XP_011 -LSLPSKTPEGGPAPPPYSEV
          190       200     

>>NP_006753 (OMIM: 601476) lysosomal-associated transmem  (262 aa)
 initn: 160 init1: 100 opt: 165  Z-score: 224.0  bits: 48.9 E(85289): 9.7e-06
Smith-Waterman score: 193; 25.0% identity (51.1% similar) in 264 aa overlap (6-223:3-259)

               10        20        30        40        50        60
pF1KE0 MKMVAPWTRFYSNSCCLCCHVRTGTILLGVWYLIINAVVLLILLSALADPDQYNFSSSEL
            :      ..:: : .:: .:  :.. : .: .:.:.:  :. .   . . . :..
NP_006    MDPRLSTVRQTCC-CFNVRIATTALAI-YHVIMSVLLFIEHSVEVAHGKASCKLSQM
                  10         20         30        40        50     

                     70        80                            90    
pF1KE0 G----GDF--EFMDDANMCIAIAISLLM--------------------ILICAMATYGAY
       :    .:.   :.   .: . :..:::.                     :.: ..  :.:
NP_006 GYLRIADLISSFLL-ITMLFIISLSLLIGVVKNREKYLLPFLSLQIMDYLLCLLTLLGSY
          60         70        80        90       100       110    

          100                   110       120       130       140  
pF1KE0 KQRAAWI------------IPFFCYQIFDFALNMLVAITVLIYPNSIQEYIRQLPPNF-P
        .  :..            .:..  :..:: :..:.  .  .   .  ..  .   :. :
NP_006 IELPAYLKLASRSRASSSKFPLMTLQLLDFCLSILTLCSSYMEVPTYLNFKSMNHMNYLP
          120       130       140       150       160       170    

             150         160       170       180       190         
pF1KE0 YRDDVMSVNPTCLVLII--LLFISIILTFKGYLISCVWNCYRYINGRNSSDVLVYVTSND
        ..: :  :    ..::  . ::.... :: :...::: ::: :.  :: .     ..  
NP_006 SQED-MPHNQFIKMMIIFSIAFITVLI-FKVYMFKCVWRCYRLIKCMNSVEEK-RNSKML
           180       190       200        210       220        230 

     200       210            220      
pF1KE0 TTVLLPPYDDATVNGAAKEP-----PPPYVSA
         :.:: :..: ..  .: :     ::::   
NP_006 QKVVLPSYEEA-LSLPSKTPEGGPAPPPYSEV
             240        250       260  




226 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 07:41:50 2016 done: Thu Nov  3 07:41:51 2016
 Total Scan time:  5.450 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]