Result of FASTA (ccds) for
pF1KE0439
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0439, 314 aa
1>>>pF1KE0439 314 - 314 aa - 314 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2702+/-0.000951; mu= 15.5832+/- 0.057
mean_var=60.6621+/-12.005, 0's: 0 Z-trim(103.7): 22 B-trim: 7 in 1/50
Lambda= 0.164670
statistics sampled from 7540 (7551) to 7540 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.601), E-opt: 0.2 (0.232), width: 16
Scan time: 2.220
The best scores are: opt bits E(32554)
CCDS3678.1 HADH gene_id:3033|Hs108|chr4 ( 314) 1972 477.1 7.6e-135
CCDS82943.1 HADH gene_id:3033|Hs108|chr4 ( 318) 1715 416.1 1.8e-116
CCDS54790.1 HADH gene_id:3033|Hs108|chr4 ( 331) 1437 350.0 1.4e-96
CCDS1721.1 HADHA gene_id:3030|Hs108|chr2 ( 763) 548 139.0 1.1e-32
CCDS54694.1 EHHADH gene_id:1962|Hs108|chr3 ( 627) 441 113.5 4.3e-25
CCDS33901.1 EHHADH gene_id:1962|Hs108|chr3 ( 723) 441 113.6 4.8e-25
CCDS41871.1 CRYL1 gene_id:51084|Hs108|chr13 ( 319) 307 81.6 9.1e-16
>>CCDS3678.1 HADH gene_id:3033|Hs108|chr4 (314 aa)
initn: 1972 init1: 1972 opt: 1972 Z-score: 2534.4 bits: 477.1 E(32554): 7.6e-135
Smith-Waterman score: 1972; 99.7% identity (99.7% similar) in 314 aa overlap (1-314:1-314)
10 20 30 40 50 60
pF1KE0 MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DILAKSKKGIEESLRKVAKKKFAENPKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAI
::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
CCDS36 DILAKSKKGIEESLRKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 VENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 VENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 VEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 VEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDAS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 KEDIDTAMKLGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 KEDIDTAMKLGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAEN
250 260 270 280 290 300
310
pF1KE0 KFGKKTGEGFYKYK
::::::::::::::
CCDS36 KFGKKTGEGFYKYK
310
>>CCDS82943.1 HADH gene_id:3033|Hs108|chr4 (318 aa)
initn: 1715 init1: 1715 opt: 1715 Z-score: 2204.3 bits: 416.1 E(32554): 1.8e-116
Smith-Waterman score: 1715; 98.2% identity (98.9% similar) in 275 aa overlap (40-314:44-318)
10 20 30 40 50 60
pF1KE0 RSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKG
: . .:::::::::::::::::::::::::
CCDS82 LGVCWRKEHDPAEMLRVGRAELGGWKPSWEAIVKEVAAATGHTVVLVDQTEDILAKSKKG
20 30 40 50 60 70
70 80 90 100 110 120
pF1KE0 IEESLRKVAKKKFAENPKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNE
:::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
CCDS82 IEESLRKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNE
80 90 100 110 120 130
130 140 150 160 170 180
pF1KE0 LFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 LFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMT
140 150 160 170 180 190
190 200 210 220 230 240
pF1KE0 SQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 SQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMK
200 210 220 230 240 250
250 260 270 280 290 300
pF1KE0 LGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 LGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEG
260 270 280 290 300 310
310
pF1KE0 FYKYK
:::::
CCDS82 FYKYK
>>CCDS54790.1 HADH gene_id:3033|Hs108|chr4 (331 aa)
initn: 1436 init1: 1436 opt: 1437 Z-score: 1847.1 bits: 350.0 E(32554): 1.4e-96
Smith-Waterman score: 1928; 94.6% identity (94.6% similar) in 331 aa overlap (1-314:1-331)
10 20 30 40 50 60
pF1KE0 MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DILAKSKKGIEESLRKVAKKKFAENPKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAI
::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
CCDS54 DILAKSKKGIEESLRKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 VENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 VENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKL
130 140 150 160 170 180
190 200 210 220 230
pF1KE0 VEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYER----
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 VEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERDFQT
190 200 210 220 230 240
240 250 260 270 280
pF1KE0 -------------GDASKEDIDTAMKLGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAE
:::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 CGDSNSGLGFSLKGDASKEDIDTAMKLGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAE
250 260 270 280 290 300
290 300 310
pF1KE0 NPLHQPSPSLNKLVAENKFGKKTGEGFYKYK
:::::::::::::::::::::::::::::::
CCDS54 NPLHQPSPSLNKLVAENKFGKKTGEGFYKYK
310 320 330
>>CCDS1721.1 HADHA gene_id:3030|Hs108|chr2 (763 aa)
initn: 380 init1: 252 opt: 548 Z-score: 700.1 bits: 139.0 E(32554): 1.1e-32
Smith-Waterman score: 548; 34.1% identity (66.2% similar) in 290 aa overlap (27-314:361-640)
10 20 30 40 50
pF1KE0 MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLV
:::....:.::::::::::.. : ..:
CCDS17 VMTKESKALMGLYHGQVLCKKNKFGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILK
340 350 360 370 380 390
60 70 80 90 100 110
pF1KE0 DQTEDILAKSKKGIEESLRKVAKKKFAENPKAGDEFVEKTLSTIATSTDAASVVHSTDLV
: : : .... . ..: .::: : : . .. . :. . ...:.:
CCDS17 DATLTALDRGQQQVFKGLNDKVKKK------ALTSFERDSIFSNLTGQLDYQGFEKADMV
400 410 420 430 440
120 130 140 150 160 170
pF1KE0 VEAIVENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVP
.::. :.:..:....:... .: :::::::.: :. :: .. : .. :.:.:.::
CCDS17 IEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALPISEIAAVSKRPEKVIGMHYFSPVD
450 460 470 480 490 500
180 190 200 210 220 230
pF1KE0 VMKLVEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYER
:.:.:.: : ::. : : : . :: . :: ::: ..: :.:.. :.::. ..
CCDS17 KMQLLEIITTEKTSKDTSASAVAVGLKQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQE
510 520 530 540 550 560
240 250 260 270 280 290
pF1KE0 G-DASKEDIDTAMKLGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSL-N
: : .: : .. . :.:.: :.: ::.:..: ... .. .: . .: : .
CCDS17 GVDPKKLD---SLTTSFGFPVGAATLVDEVGVDVAKHVAEDLGKVFGER-FGGGNPELLT
570 580 590 600 610 620
300 310
pF1KE0 KLVAENKFGKKTGEGFYKYK
..:... .:.:.:.::: :.
CCDS17 QMVSKGFLGRKSGKGFYIYQEGVKRKDLNSDMDSILASLKLPPKSEVSSDEDIQFRLVTR
630 640 650 660 670 680
>>CCDS54694.1 EHHADH gene_id:1962|Hs108|chr3 (627 aa)
initn: 468 init1: 286 opt: 441 Z-score: 564.0 bits: 113.5 E(32554): 4.3e-25
Smith-Waterman score: 455; 31.9% identity (60.1% similar) in 313 aa overlap (13-313:189-486)
10 20 30 40
pF1KE0 MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGI
:..: .:::. :. : :.: : :: ::
CCDS54 LFLYLLQSGQARALQYAFFAERKANKWSTPSGASWKTASARP--VSSVGVVGLGTMGRGI
160 170 180 190 200 210
50 60 70 80 90 100
pF1KE0 AQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKK-KFAENPKAGDEFVEKTLSTIA
. : . :. ::. .. :: ..: : :.: :.: . . .: .: . . :..
CCDS54 VISFARARIPVIAVDSDKNQLATANKMITSVLEKEASKMQQSGHPWSGPK--PRLTSSVK
220 230 240 250 260 270
110 120 130 140 150 160
pF1KE0 TSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATT
. ..:::.::. :....:...: .:. .... .:::.:.. ::..:
CCDS54 E-------LGGVDLVIEAVFEEMSLKKQVFAELSAVCKPEAFLCTNTSALDVDEIASSTD
280 290 300 310 320
170 180 190 200 210 220
pF1KE0 RQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNR
: : :::.:. ::::.::: . ..: :. .....:: . : : . ::. ::
CCDS54 RPHLVIGTHFFSPAHVMKLLEVIPSQYSSPTTIATVMNLSKKIKKIGVVVGNCFGFVGNR
330 340 350 360 370 380
230 240 250 260 270
pF1KE0 LLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLDYVGLD-----------TT
.: :: .: : :.: .. :..: ... :. ::::.. : .::: :
CCDS54 MLNPYYNQAYFLLEEG-SKPEEVDQVLEE-FGFKMGPFRVSDLAGLDVGWKSRKGQGLTG
390 400 410 420 430 440
280 290 300 310
pF1KE0 KFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKYK
.. : : . : :.. : ..::.:::.:.:.:
CCDS54 PTLLPGTPARKRGNRRYCPIPDV--LCELGRFGQKTGKGWYQYDKPLGRIHKPDPWLSKF
450 460 470 480 490 500
CCDS54 LSRYRKTHHIEPRTISQDEILERCLYSLINEAFRILGEGIAASPEHIDVVYLHGYGWPRH
510 520 530 540 550 560
>>CCDS33901.1 EHHADH gene_id:1962|Hs108|chr3 (723 aa)
initn: 468 init1: 286 opt: 441 Z-score: 563.1 bits: 113.6 E(32554): 4.8e-25
Smith-Waterman score: 455; 31.9% identity (60.1% similar) in 313 aa overlap (13-313:285-582)
10 20 30 40
pF1KE0 MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGI
:..: .:::. :. : :.: : :: ::
CCDS33 LFLYLLQSGQARALQYAFFAERKANKWSTPSGASWKTASARP--VSSVGVVGLGTMGRGI
260 270 280 290 300 310
50 60 70 80 90 100
pF1KE0 AQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKK-KFAENPKAGDEFVEKTLSTIA
. : . :. ::. .. :: ..: : :.: :.: . . .: .: . . :..
CCDS33 VISFARARIPVIAVDSDKNQLATANKMITSVLEKEASKMQQSGHPWSGPK--PRLTSSVK
320 330 340 350 360 370
110 120 130 140 150 160
pF1KE0 TSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATT
. ..:::.::. :....:...: .:. .... .:::.:.. ::..:
CCDS33 E-------LGGVDLVIEAVFEEMSLKKQVFAELSAVCKPEAFLCTNTSALDVDEIASSTD
380 390 400 410 420
170 180 190 200 210 220
pF1KE0 RQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNR
: : :::.:. ::::.::: . ..: :. .....:: . : : . ::. ::
CCDS33 RPHLVIGTHFFSPAHVMKLLEVIPSQYSSPTTIATVMNLSKKIKKIGVVVGNCFGFVGNR
430 440 450 460 470 480
230 240 250 260 270
pF1KE0 LLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLDYVGLD-----------TT
.: :: .: : :.: .. :..: ... :. ::::.. : .::: :
CCDS33 MLNPYYNQAYFLLEEG-SKPEEVDQVLEE-FGFKMGPFRVSDLAGLDVGWKSRKGQGLTG
490 500 510 520 530 540
280 290 300 310
pF1KE0 KFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKYK
.. : : . : :.. : ..::.:::.:.:.:
CCDS33 PTLLPGTPARKRGNRRYCPIPDV--LCELGRFGQKTGKGWYQYDKPLGRIHKPDPWLSKF
550 560 570 580 590
CCDS33 LSRYRKTHHIEPRTISQDEILERCLYSLINEAFRILGEGIAASPEHIDVVYLHGYGWPRH
600 610 620 630 640 650
>>CCDS41871.1 CRYL1 gene_id:51084|Hs108|chr13 (319 aa)
initn: 238 init1: 150 opt: 307 Z-score: 396.5 bits: 81.6 E(32554): 9.1e-16
Smith-Waterman score: 307; 28.3% identity (59.1% similar) in 237 aa overlap (30-262:9-241)
10 20 30 40 50 60
pF1KE0 MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTE
:...:.:..: . :.. :. : : : :
CCDS41 MASSAAGCVVIVGSGVIGRSWAMLFASGGFQVKLYD---
10 20 30
70 80 90 100 110 120
pF1KE0 DILAKSKKGIEESLRKVAKKKFAENPKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAI
: .. .. :..:: : . :. ::. :: :. . .:... . : .
CCDS41 -IEQQQIRNALENIRKEMKLLEQAGSLKGSLSVEEQLSLISGCPNIQEAVEGAMHIQECV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE0 VENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKL
:.:..:...: .::.. ...:..:.:: :. ... . .. . : :: . :
CCDS41 PEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSKLFAGLVHVKQCIVAHPVNPPYYIPL
100 110 120 130 140 150
190 200 210 220 230
pF1KE0 VEVIKTPMTSQKTFESLVDFSKALGKHPVSC-KDTPGFIVNRLLVPYLMEAIRLYERGDA
::.. : :. : . . : .:. :. :.. ::..::: . :: :: :.: .
CCDS41 VELVPHPETAPTTVDRTHALMKKIGQCPMRVQKEVAGFVLNRLQYAIISEAWRLVEEGIV
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE0 SKEDIDTAMKLGAGYP---MGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKL
: :.: .:. : :. .::.: .
CCDS41 SPSDLDLVMSEGLGMRYAFIGPLETMHLNAEGMLSYCDRYSEGIKHVLQTFGPIPEFSRA
220 230 240 250 260 270
314 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 08:54:35 2016 done: Thu Nov 3 08:54:35 2016
Total Scan time: 2.220 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]