Result of FASTA (omim) for
pF1KE0425
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0425, 373 aa
1>>>pF1KE0425 373 - 373 aa - 373 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7706+/-0.000423; mu= 19.2773+/- 0.026
mean_var=66.6965+/-13.638, 0's: 0 Z-trim(111.2): 44 B-trim: 22 in 1/52
Lambda= 0.157044
statistics sampled from 19748 (19792) to 19748 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.614), E-opt: 0.2 (0.232), width: 16
Scan time: 7.540
The best scores are: opt bits E(85289)
NP_001123237 (OMIM: 300275,300831,308050) sterol-4 ( 373) 2485 572.3 6.3e-163
XP_011529480 (OMIM: 300275,300831,308050) PREDICTE ( 373) 2485 572.3 6.3e-163
NP_057006 (OMIM: 300275,300831,308050) sterol-4-al ( 373) 2485 572.3 6.3e-163
XP_016885053 (OMIM: 300275,300831,308050) PREDICTE ( 389) 2485 572.3 6.5e-163
XP_011521773 (OMIM: 616164) PREDICTED: short-chain ( 390) 514 125.7 1.8e-28
XP_011521774 (OMIM: 616164) PREDICTED: short-chain ( 390) 514 125.7 1.8e-28
XP_005256314 (OMIM: 616164) PREDICTED: short-chain ( 393) 514 125.7 1.8e-28
NP_660151 (OMIM: 616164) short-chain dehydrogenase ( 393) 514 125.7 1.8e-28
NP_001315544 (OMIM: 109715) 3 beta-hydroxysteroid ( 373) 324 82.7 1.5e-15
NP_000853 (OMIM: 109715) 3 beta-hydroxysteroid deh ( 373) 324 82.7 1.5e-15
XP_016856608 (OMIM: 109715) PREDICTED: 3 beta-hydr ( 375) 324 82.7 1.6e-15
NP_000189 (OMIM: 201810,613890) 3 beta-hydroxyster ( 372) 303 77.9 4.2e-14
NP_001159592 (OMIM: 201810,613890) 3 beta-hydroxys ( 372) 303 77.9 4.2e-14
XP_011544262 (OMIM: 607764,607765) PREDICTED: 3 be ( 369) 286 74.1 6e-13
XP_005255658 (OMIM: 607764,607765) PREDICTED: 3 be ( 369) 286 74.1 6e-13
NP_079469 (OMIM: 607764,607765) 3 beta-hydroxyster ( 369) 286 74.1 6e-13
XP_011544263 (OMIM: 607764,607765) PREDICTED: 3 be ( 369) 286 74.1 6e-13
XP_016860499 (OMIM: 609749) PREDICTED: UDP-glucuro ( 357) 210 56.8 8.9e-08
XP_006712838 (OMIM: 609749) PREDICTED: UDP-glucuro ( 362) 210 56.8 9e-08
XP_016860498 (OMIM: 609749) PREDICTED: UDP-glucuro ( 366) 210 56.8 9.1e-08
XP_016860497 (OMIM: 609749) PREDICTED: UDP-glucuro ( 371) 210 56.8 9.2e-08
XP_011510205 (OMIM: 609749) PREDICTED: UDP-glucuro ( 414) 210 56.9 1e-07
XP_011510204 (OMIM: 609749) PREDICTED: UDP-glucuro ( 419) 210 56.9 1e-07
NP_079352 (OMIM: 609749) UDP-glucuronic acid decar ( 420) 210 56.9 1e-07
NP_001240804 (OMIM: 609749) UDP-glucuronic acid de ( 425) 210 56.9 1e-07
XP_011510206 (OMIM: 609749) PREDICTED: UDP-glucuro ( 365) 195 53.4 9.6e-07
XP_016860500 (OMIM: 609749) PREDICTED: UDP-glucuro ( 355) 189 52.1 2.4e-06
XP_016860501 (OMIM: 609749) PREDICTED: UDP-glucuro ( 355) 189 52.1 2.4e-06
XP_016860502 (OMIM: 609749) PREDICTED: UDP-glucuro ( 312) 169 47.5 5e-05
NP_001136249 (OMIM: 607764,607765) 3 beta-hydroxys ( 196) 162 45.7 0.00011
XP_011544264 (OMIM: 607764,607765) PREDICTED: 3 be ( 196) 162 45.7 0.00011
XP_016879221 (OMIM: 607764,607765) PREDICTED: 3 be ( 196) 162 45.7 0.00011
NP_001136250 (OMIM: 607764,607765) 3 beta-hydroxys ( 196) 162 45.7 0.00011
XP_011519367 (OMIM: 616145,616146) PREDICTED: dTDP ( 318) 157 44.8 0.00034
NP_001291359 (OMIM: 616145,616146) dTDP-D-glucose ( 318) 157 44.8 0.00034
XP_011519368 (OMIM: 616145,616146) PREDICTED: dTDP ( 318) 157 44.8 0.00034
XP_016860503 (OMIM: 609749) PREDICTED: UDP-glucuro ( 252) 137 40.2 0.0065
NP_001240805 (OMIM: 609749) UDP-glucuronic acid de ( 252) 137 40.2 0.0065
>>NP_001123237 (OMIM: 300275,300831,308050) sterol-4-alp (373 aa)
initn: 2485 init1: 2485 opt: 2485 Z-score: 3046.0 bits: 572.3 E(85289): 6.3e-163
Smith-Waterman score: 2485; 100.0% identity (100.0% similar) in 373 aa overlap (1-373:1-373)
10 20 30 40 50 60
pF1KE0 MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 RAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 YYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAME
310 320 330 340 350 360
370
pF1KE0 RTVQSFRHLRRVK
:::::::::::::
NP_001 RTVQSFRHLRRVK
370
>>XP_011529480 (OMIM: 300275,300831,308050) PREDICTED: s (373 aa)
initn: 2485 init1: 2485 opt: 2485 Z-score: 3046.0 bits: 572.3 E(85289): 6.3e-163
Smith-Waterman score: 2485; 100.0% identity (100.0% similar) in 373 aa overlap (1-373:1-373)
10 20 30 40 50 60
pF1KE0 MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 RAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 YYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAME
310 320 330 340 350 360
370
pF1KE0 RTVQSFRHLRRVK
:::::::::::::
XP_011 RTVQSFRHLRRVK
370
>>NP_057006 (OMIM: 300275,300831,308050) sterol-4-alpha- (373 aa)
initn: 2485 init1: 2485 opt: 2485 Z-score: 3046.0 bits: 572.3 E(85289): 6.3e-163
Smith-Waterman score: 2485; 100.0% identity (100.0% similar) in 373 aa overlap (1-373:1-373)
10 20 30 40 50 60
pF1KE0 MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 RAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 RAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 ENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 YYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 YYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAME
310 320 330 340 350 360
370
pF1KE0 RTVQSFRHLRRVK
:::::::::::::
NP_057 RTVQSFRHLRRVK
370
>>XP_016885053 (OMIM: 300275,300831,308050) PREDICTED: s (389 aa)
initn: 2485 init1: 2485 opt: 2485 Z-score: 3045.8 bits: 572.3 E(85289): 6.5e-163
Smith-Waterman score: 2485; 100.0% identity (100.0% similar) in 373 aa overlap (1-373:17-389)
10 20 30 40
pF1KE0 MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIG
::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRKEKLITNGTIFCFEMEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIG
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 GSGFLGQHMVEQLLARGYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGFLGQHMVEQLLARGYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHC
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 ASPPPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASPPPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPY
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE0 AMKPIDYYTETKILQERAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AMKPIDYYTETKILQERAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKM
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE0 KFVIGNGKNLVDFTFVENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFVIGNGKNLVDFTFVENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILT
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE0 GLNYEAPKYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLNYEAPKYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAK
310 320 330 340 350 360
350 360 370
pF1KE0 KAMGYQPLVTMDDAMERTVQSFRHLRRVK
:::::::::::::::::::::::::::::
XP_016 KAMGYQPLVTMDDAMERTVQSFRHLRRVK
370 380
>>XP_011521773 (OMIM: 616164) PREDICTED: short-chain deh (390 aa)
initn: 447 init1: 171 opt: 514 Z-score: 632.3 bits: 125.7 E(85289): 1.8e-28
Smith-Waterman score: 563; 34.5% identity (66.1% similar) in 319 aa overlap (61-360:29-345)
40 50 60 70 80
pF1KE0 KVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDN-PQ-VRFFLGDLCSR
: : .:::.. .. :. ..:. ::.
XP_011 MHSEGLRMSQEDLDQPHLDCLGCALNQNGVHVILFDISSPAQTIPEGIKFIQGDIRHL
10 20 30 40 50
90 100 110 120 130 140
pF1KE0 QDLYPALKG--VNTVFHCASPPPSSN---NKELFYRVNYIGTKNVIETCKEAGVQKLILT
.:. :.. :. ::: :: :. :..:. .:: :: :....:.. : .:. :
XP_011 SDVEKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYT
60 70 80 90 100 110
150 160 170 180 190
pF1KE0 SSASVIFEGVDIKNGTEDLPYA---MKPIDYYTETKILQERAVLGAN----DPEKNFLTT
:. .::: : :.:: :.::: ..: :.:..:: . :. :: :: : . : :
XP_011 STFNVIFGGQVIRNGDESLPYLPLHLHP-DHYSRTKSIAEQKVLEANATPLDRGDGVLRT
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE0 -AIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQLS
:.:: ::.:: . . .: .. ..: .::: :. ..::.:. :.:.:..::::.: :
XP_011 CALRPAGIYGPGEQRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALR
180 190 200 210 220 230
260 270 280 290 300 310
pF1KE0 RDS--TLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVAYYLALLLSLLVMV
:. .:. . :.. .:. . :. .. ::.: :. ..: ..: .:.: .. ..
XP_011 ADKGHIASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSTRLPLTLVYCFAFLTEMVHFI
240 250 260 270 280 290
320 330 340 350 360 370
pF1KE0 ISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGY--QPLVTMDDAMERTVQSFRHLRR
.. . ..:: .: .: .:. ::.: :.::: .:: ::. ...:.:
XP_011 LGRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYKAQPF-DLQEAVEWFKAHGHGRSS
300 310 320 330 340 350
pF1KE0 VK
XP_011 GSRDSECFVWDGLLVFLLIIAVLMWLPSSVILSL
360 370 380 390
>>XP_011521774 (OMIM: 616164) PREDICTED: short-chain deh (390 aa)
initn: 447 init1: 171 opt: 514 Z-score: 632.3 bits: 125.7 E(85289): 1.8e-28
Smith-Waterman score: 563; 34.5% identity (66.1% similar) in 319 aa overlap (61-360:29-345)
40 50 60 70 80
pF1KE0 KVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDN-PQ-VRFFLGDLCSR
: : .:::.. .. :. ..:. ::.
XP_011 MHSEGLRMSQEDLDQPHLDCLGCALNQNGVHVILFDISSPAQTIPEGIKFIQGDIRHL
10 20 30 40 50
90 100 110 120 130 140
pF1KE0 QDLYPALKG--VNTVFHCASPPPSSN---NKELFYRVNYIGTKNVIETCKEAGVQKLILT
.:. :.. :. ::: :: :. :..:. .:: :: :....:.. : .:. :
XP_011 SDVEKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYT
60 70 80 90 100 110
150 160 170 180 190
pF1KE0 SSASVIFEGVDIKNGTEDLPYA---MKPIDYYTETKILQERAVLGAN----DPEKNFLTT
:. .::: : :.:: :.::: ..: :.:..:: . :. :: :: : . : :
XP_011 STFNVIFGGQVIRNGDESLPYLPLHLHP-DHYSRTKSIAEQKVLEANATPLDRGDGVLRT
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE0 -AIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQLS
:.:: ::.:: . . .: .. ..: .::: :. ..::.:. :.:.:..::::.: :
XP_011 CALRPAGIYGPGEQRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALR
180 190 200 210 220 230
260 270 280 290 300 310
pF1KE0 RDS--TLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVAYYLALLLSLLVMV
:. .:. . :.. .:. . :. .. ::.: :. ..: ..: .:.: .. ..
XP_011 ADKGHIASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSTRLPLTLVYCFAFLTEMVHFI
240 250 260 270 280 290
320 330 340 350 360 370
pF1KE0 ISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGY--QPLVTMDDAMERTVQSFRHLRR
.. . ..:: .: .: .:. ::.: :.::: .:: ::. ...:.:
XP_011 LGRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYKAQPF-DLQEAVEWFKAHGHGRSS
300 310 320 330 340 350
pF1KE0 VK
XP_011 GSRDSECFVWDGLLVFLLIIAVLMWLPSSVILSL
360 370 380 390
>>XP_005256314 (OMIM: 616164) PREDICTED: short-chain deh (393 aa)
initn: 503 init1: 171 opt: 514 Z-score: 632.3 bits: 125.7 E(85289): 1.8e-28
Smith-Waterman score: 604; 33.8% identity (65.3% similar) in 346 aa overlap (34-360:5-348)
10 20 30 40 50 60
pF1KE0 AVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYA
..: . . ::::..: .. : :
XP_005 MDPKRSQKESVLITGGSGYFGFRLGCALNQNGVH
10 20 30
70 80 90 100 110
pF1KE0 VNVFDIQQGFDN-PQ-VRFFLGDLCSRQDLYPALKG--VNTVFHCASPPPSSN---NKEL
: .:::.. .. :. ..:. ::. .:. :.. :. ::: :: :. :..:
XP_005 VILFDISSPAQTIPEGIKFIQGDIRHLSDVEKAFQDADVTCVFHIASYGMSGREQLNRNL
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE0 FYRVNYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYA---MKPIDYYT
. .:: :: :....:.. : .:. ::. .::: : :.:: :.::: ..: :.:.
XP_005 IKEVNVRGTDNILQVCQRRRVPRLVYTSTFNVIFGGQVIRNGDESLPYLPLHLHP-DHYS
100 110 120 130 140 150
180 190 200 210 220
pF1KE0 ETKILQERAVLGAN----DPEKNFLTT-AIRPHGIFGPRDPQLVPILIEAARNGKMKFVI
.:: . :. :: :: : . : : :.:: ::.:: . . .: .. ..: .:::
XP_005 RTKSIAEQKVLEANATPLDRGDGVLRTCALRPAGIYGPGEQRHLPRIVSYIEKGLFKFVY
160 170 180 190 200 210
230 240 250 260 270 280
pF1KE0 GNGKNLVDFTFVENVVHGHILAAEQLSRDS--TLGGKAFHITNDEPIPFWTFLSRILTGL
:. ..::.:. :.:.:..::::.: : :. .:. . :.. .:. . :. .. ::
XP_005 GDPRSLVEFVHVDNLVQAHILASEALRADKGHIASGQPYFISDGRPVNNFEFFRPLVEGL
220 230 240 250 260 270
290 300 310 320 330 340
pF1KE0 NYEAPKYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKA
.: :. ..: ..: .:.: .. .... . ..:: .: .: .:. ::.: :.:::
XP_005 GYTFPSTRLPLTLVYCFAFLTEMVHFILGRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKE
280 290 300 310 320 330
350 360 370
pF1KE0 MGY--QPLVTMDDAMERTVQSFRHLRRVK
.:: ::. ...:.:
XP_005 LGYKAQPF-DLQEAVEWFKAHGHGRSSGSRDSECFVWDGLLVFLLIIAVLMWLPSSVILS
340 350 360 370 380 390
>>NP_660151 (OMIM: 616164) short-chain dehydrogenase/red (393 aa)
initn: 503 init1: 171 opt: 514 Z-score: 632.3 bits: 125.7 E(85289): 1.8e-28
Smith-Waterman score: 604; 33.8% identity (65.3% similar) in 346 aa overlap (34-360:5-348)
10 20 30 40 50 60
pF1KE0 AVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYA
..: . . ::::..: .. : :
NP_660 MDPKRSQKESVLITGGSGYFGFRLGCALNQNGVH
10 20 30
70 80 90 100 110
pF1KE0 VNVFDIQQGFDN-PQ-VRFFLGDLCSRQDLYPALKG--VNTVFHCASPPPSSN---NKEL
: .:::.. .. :. ..:. ::. .:. :.. :. ::: :: :. :..:
NP_660 VILFDISSPAQTIPEGIKFIQGDIRHLSDVEKAFQDADVTCVFHIASYGMSGREQLNRNL
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE0 FYRVNYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYA---MKPIDYYT
. .:: :: :....:.. : .:. ::. .::: : :.:: :.::: ..: :.:.
NP_660 IKEVNVRGTDNILQVCQRRRVPRLVYTSTFNVIFGGQVIRNGDESLPYLPLHLHP-DHYS
100 110 120 130 140 150
180 190 200 210 220
pF1KE0 ETKILQERAVLGAN----DPEKNFLTT-AIRPHGIFGPRDPQLVPILIEAARNGKMKFVI
.:: . :. :: :: : . : : :.:: ::.:: . . .: .. ..: .:::
NP_660 RTKSIAEQKVLEANATPLDRGDGVLRTCALRPAGIYGPGEQRHLPRIVSYIEKGLFKFVY
160 170 180 190 200 210
230 240 250 260 270 280
pF1KE0 GNGKNLVDFTFVENVVHGHILAAEQLSRDS--TLGGKAFHITNDEPIPFWTFLSRILTGL
:. ..::.:. :.:.:..::::.: : :. .:. . :.. .:. . :. .. ::
NP_660 GDPRSLVEFVHVDNLVQAHILASEALRADKGHIASGQPYFISDGRPVNNFEFFRPLVEGL
220 230 240 250 260 270
290 300 310 320 330 340
pF1KE0 NYEAPKYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKA
.: :. ..: ..: .:.: .. .... . ..:: .: .: .:. ::.: :.:::
NP_660 GYTFPSTRLPLTLVYCFAFLTEMVHFILGRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKE
280 290 300 310 320 330
350 360 370
pF1KE0 MGY--QPLVTMDDAMERTVQSFRHLRRVK
.:: ::. ...:.:
NP_660 LGYKAQPF-DLQEAVEWFKAHGHGRSSGSRDSECFVWDGLLVFLLIIAVLMWLPSSVILS
340 350 360 370 380 390
>>NP_001315544 (OMIM: 109715) 3 beta-hydroxysteroid dehy (373 aa)
initn: 206 init1: 70 opt: 324 Z-score: 399.9 bits: 82.7 E(85289): 1.5e-15
Smith-Waterman score: 378; 27.2% identity (58.9% similar) in 353 aa overlap (40-364:6-355)
10 20 30 40 50 60
pF1KE0 RDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGY--AVNVF
: : :..:::::.... :. . . :.
NP_001 MTGWSCLVTGAGGFLGQRIIRLLVKEKELKEIRVL
10 20 30
70 80 90 100 110
pF1KE0 D------IQQGFDNPQVRFFL----GDLCSRQDLYPALKGVNTVFH--CASPPPSSNNKE
: ... :.. : . : ::. .. : : . :....: : . ...:
NP_001 DKAFGPELREEFSKLQNKTKLTVLEGDILDEPFLKRACQDVSVIIHTACIIDVFGVTHRE
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE0 LFYRVNYIGTKNVIETCKEAGVQKLILTSSASVI----FEGVDIKNGTEDLPYAMKPIDY
.. :: ::. ..:.: .:.: .: ::: : .. . :.:: :. :
NP_001 SIMNVNVKGTQLLLEACVQASVPVFIYTSSIEVAGPNSYKEI-IQNGHEEEPLENTWPAP
100 110 120 130 140 150
180 190 200 210 220
pF1KE0 YTETKILQERAVLGANDPE-KN---FLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFV
: ..: : :.:::.:: . :: . : :.:: :.: . : . :: :. .
NP_001 YPHSKKLAEKAVLAANGWNLKNGGTLYTCALRPMYIYGEGSRFLSASINEALNNNGILSS
160 170 180 190 200 210
230 240 250 260 270 280
pF1KE0 IGNGKNLVDFTFVENVVHGHILAAEQLS---RDSTLGGKAFHITNDEPIPFWTFLSRILT
.:. .. :. ..: ::. .:::: . :. . .. :. ..:..: : . :. :.
NP_001 VGKFST-VNPVYVGNVAWAHILALRALQDPKKAPSIRGQFYYISDDTPHQSYDNLNYTLS
220 230 240 250 260 270
290 300 310 320 330 340
pF1KE0 ---GLNYEAPKYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCE
:: .. .. .: . :....:: .. ... :. .: :. :.:... .: .
NP_001 KEFGLRLDS-RWSFPLSLMYWIGFLLEIVSFLLRPIYTYRPPFNRHIVTLSNSVFTFSYK
280 290 300 310 320 330
350 360 370
pF1KE0 RAKKAMGYQPLVTMDDAMERTVQSFRHLRRVK
.:.. ..:.:: . ..: ..::.
NP_001 KAQRDLAYKPLYSWEEAKQKTVEWVGSLVDRHKETLKSKTQ
340 350 360 370
>>NP_000853 (OMIM: 109715) 3 beta-hydroxysteroid dehydro (373 aa)
initn: 206 init1: 70 opt: 324 Z-score: 399.9 bits: 82.7 E(85289): 1.5e-15
Smith-Waterman score: 378; 27.2% identity (58.9% similar) in 353 aa overlap (40-364:6-355)
10 20 30 40 50 60
pF1KE0 RDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGY--AVNVF
: : :..:::::.... :. . . :.
NP_000 MTGWSCLVTGAGGFLGQRIIRLLVKEKELKEIRVL
10 20 30
70 80 90 100 110
pF1KE0 D------IQQGFDNPQVRFFL----GDLCSRQDLYPALKGVNTVFH--CASPPPSSNNKE
: ... :.. : . : ::. .. : : . :....: : . ...:
NP_000 DKAFGPELREEFSKLQNKTKLTVLEGDILDEPFLKRACQDVSVIIHTACIIDVFGVTHRE
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE0 LFYRVNYIGTKNVIETCKEAGVQKLILTSSASVI----FEGVDIKNGTEDLPYAMKPIDY
.. :: ::. ..:.: .:.: .: ::: : .. . :.:: :. :
NP_000 SIMNVNVKGTQLLLEACVQASVPVFIYTSSIEVAGPNSYKEI-IQNGHEEEPLENTWPAP
100 110 120 130 140 150
180 190 200 210 220
pF1KE0 YTETKILQERAVLGANDPE-KN---FLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFV
: ..: : :.:::.:: . :: . : :.:: :.: . : . :: :. .
NP_000 YPHSKKLAEKAVLAANGWNLKNGGTLYTCALRPMYIYGEGSRFLSASINEALNNNGILSS
160 170 180 190 200 210
230 240 250 260 270 280
pF1KE0 IGNGKNLVDFTFVENVVHGHILAAEQLS---RDSTLGGKAFHITNDEPIPFWTFLSRILT
.:. .. :. ..: ::. .:::: . :. . .. :. ..:..: : . :. :.
NP_000 VGKFST-VNPVYVGNVAWAHILALRALQDPKKAPSIRGQFYYISDDTPHQSYDNLNYTLS
220 230 240 250 260 270
290 300 310 320 330 340
pF1KE0 ---GLNYEAPKYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCE
:: .. .. .: . :....:: .. ... :. .: :. :.:... .: .
NP_000 KEFGLRLDS-RWSFPLSLMYWIGFLLEIVSFLLRPIYTYRPPFNRHIVTLSNSVFTFSYK
280 290 300 310 320 330
350 360 370
pF1KE0 RAKKAMGYQPLVTMDDAMERTVQSFRHLRRVK
.:.. ..:.:: . ..: ..::.
NP_000 KAQRDLAYKPLYSWEEAKQKTVEWVGSLVDRHKETLKSKTQ
340 350 360 370
373 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 10:36:41 2016 done: Thu Nov 3 10:36:42 2016
Total Scan time: 7.540 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]