Result of FASTA (omim) for
pF1KE0422
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0422, 393 aa
1>>>pF1KE0422 393 - 393 aa - 393 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7575+/-0.000445; mu= 13.8735+/- 0.028
mean_var=66.6455+/-13.492, 0's: 0 Z-trim(110.1): 37 B-trim: 5 in 1/53
Lambda= 0.157105
statistics sampled from 18316 (18332) to 18316 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.587), E-opt: 0.2 (0.215), width: 16
Scan time: 7.400
The best scores are: opt bits E(85289)
NP_004126 (OMIM: 300089) isocitrate dehydrogenase ( 393) 2553 588.0 1.3e-167
NP_777358 (OMIM: 300089) isocitrate dehydrogenase ( 380) 2348 541.5 1.2e-153
NP_008830 (OMIM: 604526,612572) isocitrate dehydro ( 385) 1169 274.3 3.4e-73
NP_001317692 (OMIM: 604526,612572) isocitrate dehy ( 387) 1169 274.3 3.5e-73
NP_777280 (OMIM: 604526,612572) isocitrate dehydro ( 383) 1144 268.6 1.7e-71
NP_001245313 (OMIM: 604526,612572) isocitrate dehy ( 376) 1114 261.8 1.9e-69
NP_005521 (OMIM: 601149) isocitrate dehydrogenase ( 366) 928 219.7 9.1e-57
XP_016877607 (OMIM: 601149) PREDICTED: isocitrate ( 316) 820 195.2 1.9e-49
XP_016877609 (OMIM: 601149) PREDICTED: isocitrate ( 257) 773 184.5 2.5e-46
XP_005254393 (OMIM: 601149) PREDICTED: isocitrate ( 257) 773 184.5 2.5e-46
XP_016877608 (OMIM: 601149) PREDICTED: isocitrate ( 257) 773 184.5 2.5e-46
>>NP_004126 (OMIM: 300089) isocitrate dehydrogenase [NAD (393 aa)
initn: 2553 init1: 2553 opt: 2553 Z-score: 3130.1 bits: 588.0 E(85289): 1.3e-167
Smith-Waterman score: 2553; 100.0% identity (100.0% similar) in 393 aa overlap (1-393:1-393)
10 20 30 40 50 60
pF1KE0 MALKVATVAGSAAKAVLGPALLCRPWEVLGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MALKVATVAGSAAKAVLGPALLCRPWEVLGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNAIMAIRRNRVALKGNIET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNAIMAIRRNRVALKGNIET
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 NHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 SVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 HVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNEN
310 320 330 340 350 360
370 380 390
pF1KE0 MHTPDIGGQGTTSEAIQDVIRHIRVINGRAVEA
:::::::::::::::::::::::::::::::::
NP_004 MHTPDIGGQGTTSEAIQDVIRHIRVINGRAVEA
370 380 390
>>NP_777358 (OMIM: 300089) isocitrate dehydrogenase [NAD (380 aa)
initn: 2377 init1: 2348 opt: 2348 Z-score: 2879.3 bits: 541.5 E(85289): 1.2e-153
Smith-Waterman score: 2348; 99.2% identity (99.7% similar) in 364 aa overlap (1-364:1-364)
10 20 30 40 50 60
pF1KE0 MALKVATVAGSAAKAVLGPALLCRPWEVLGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 MALKVATVAGSAAKAVLGPALLCRPWEVLGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNAIMAIRRNRVALKGNIET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 PGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNAIMAIRRNRVALKGNIET
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 NHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 NHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 SVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 SVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 ARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 HVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 HVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNEN
310 320 330 340 350 360
370 380 390
pF1KE0 MHTPDIGGQGTTSEAIQDVIRHIRVINGRAVEA
.. :
NP_777 VRFPSHPTLLPRPVSPCSLL
370 380
>>NP_008830 (OMIM: 604526,612572) isocitrate dehydrogena (385 aa)
initn: 1190 init1: 1010 opt: 1169 Z-score: 1435.0 bits: 274.3 E(85289): 3.4e-73
Smith-Waterman score: 1169; 54.6% identity (78.5% similar) in 335 aa overlap (53-384:47-381)
30 40 50 60 70 80
pF1KE0 CRPWEVLGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACV
: :::.::::.::::: :: ::. : :
NP_008 AGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAV
20 30 40 50 60 70
90 100 110 120 130
pF1KE0 PVDFEEVHVS---SNADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSL
::.:.: :.: . :.:: ..... ....:.::. :.:.: . : . :: .:
NP_008 PVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRKL
80 90 100 110 120 130
140 150 160 170 180 190
pF1KE0 DLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLR
::.:::.: ::::: .:::...:..:.::.::::::::::::. ::.: :::.:.::: :
NP_008 DLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQR
140 150 160 170 180 190
200 210 220 230 240 250
pF1KE0 IAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQ
::..:: : ..:: ::::::::::::::::::::::.::: ::.: ::.::.:: ::
NP_008 IAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQ
200 210 220 230 240 250
260 270 280 290 300 310
pF1KE0 LVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIAN
::. : ::::.:::::::::..:. :::::: :.: : .:. ::::::..:. . ..
NP_008 LVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVG
260 270 280 290 300 310
320 330 340 350 360 370
pF1KE0 KNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDV
.::::::: ::.. :: ::.:. ... : :: . ...: :.:: .::.. :..:
NP_008 RNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKSV
320 330 340 350 360 370
380 390
pF1KE0 IRHIRVINGRAVEA
: :..
NP_008 IGHLQTKGS
380
>>NP_001317692 (OMIM: 604526,612572) isocitrate dehydrog (387 aa)
initn: 1190 init1: 1010 opt: 1169 Z-score: 1434.9 bits: 274.3 E(85289): 3.5e-73
Smith-Waterman score: 1169; 54.6% identity (78.5% similar) in 335 aa overlap (53-384:47-381)
30 40 50 60 70 80
pF1KE0 CRPWEVLGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACV
: :::.::::.::::: :: ::. : :
NP_001 AGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAV
20 30 40 50 60 70
90 100 110 120 130
pF1KE0 PVDFEEVHVS---SNADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSL
::.:.: :.: . :.:: ..... ....:.::. :.:.: . : . :: .:
NP_001 PVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRKL
80 90 100 110 120 130
140 150 160 170 180 190
pF1KE0 DLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLR
::.:::.: ::::: .:::...:..:.::.::::::::::::. ::.: :::.:.::: :
NP_001 DLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQR
140 150 160 170 180 190
200 210 220 230 240 250
pF1KE0 IAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQ
::..:: : ..:: ::::::::::::::::::::::.::: ::.: ::.::.:: ::
NP_001 IAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQ
200 210 220 230 240 250
260 270 280 290 300 310
pF1KE0 LVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIAN
::. : ::::.:::::::::..:. :::::: :.: : .:. ::::::..:. . ..
NP_001 LVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVG
260 270 280 290 300 310
320 330 340 350 360 370
pF1KE0 KNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDV
.::::::: ::.. :: ::.:. ... : :: . ...: :.:: .::.. :..:
NP_001 RNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKSV
320 330 340 350 360 370
380 390
pF1KE0 IRHIRVINGRAVEA
: :..
NP_001 IGHLQTKGSNL
380
>>NP_777280 (OMIM: 604526,612572) isocitrate dehydrogena (383 aa)
initn: 1174 init1: 994 opt: 1144 Z-score: 1404.4 bits: 268.6 E(85289): 1.7e-71
Smith-Waterman score: 1144; 54.4% identity (77.3% similar) in 331 aa overlap (53-380:47-377)
30 40 50 60 70 80
pF1KE0 CRPWEVLGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACV
: :::.::::.::::: :: ::. : :
NP_777 AGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAV
20 30 40 50 60 70
90 100 110 120 130
pF1KE0 PVDFEEVHVS---SNADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSL
::.:.: :.: . :.:: ..... ....:.::. :.:.: . : . :: .:
NP_777 PVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRKL
80 90 100 110 120 130
140 150 160 170 180 190
pF1KE0 DLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLR
::.:::.: ::::: .:::...:..:.::.::::::::::::. ::.: :::.:.::: :
NP_777 DLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQR
140 150 160 170 180 190
200 210 220 230 240 250
pF1KE0 IAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQ
::..:: : ..:: ::::::::::::::::::::::.::: ::.: ::.::.:: ::
NP_777 IAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQ
200 210 220 230 240 250
260 270 280 290 300 310
pF1KE0 LVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIAN
::. : ::::.:::::::::..:. :::::: :.: : .:. ::::::..:. . ..
NP_777 LVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVG
260 270 280 290 300 310
320 330 340 350 360 370
pF1KE0 KNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDV
.::::::: ::.. :: ::.:. ... : :: . ...: :.:: .: . . :
NP_777 RNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTSDMGGYATCHDFTEAV
320 330 340 350 360 370
380 390
pF1KE0 IRHIRVINGRAVEA
:
NP_777 IAALPHP
380
>>NP_001245313 (OMIM: 604526,612572) isocitrate dehydrog (376 aa)
initn: 1144 init1: 964 opt: 1114 Z-score: 1367.8 bits: 261.8 E(85289): 1.9e-69
Smith-Waterman score: 1114; 57.1% identity (79.5% similar) in 303 aa overlap (53-352:47-349)
30 40 50 60 70 80
pF1KE0 CRPWEVLGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACV
: :::.::::.::::: :: ::. : :
NP_001 AGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAV
20 30 40 50 60 70
90 100 110 120 130
pF1KE0 PVDFEEVHVS---SNADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSL
::.:.: :.: . :.:: ..... ....:.::. :.:.: . : . :: .:
NP_001 PVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRKL
80 90 100 110 120 130
140 150 160 170 180 190
pF1KE0 DLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLR
::.:::.: ::::: .:::...:..:.::.::::::::::::. ::.: :::.:.::: :
NP_001 DLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQR
140 150 160 170 180 190
200 210 220 230 240 250
pF1KE0 IAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQ
::..:: : ..:: ::::::::::::::::::::::.::: ::.: ::.::.:: ::
NP_001 IAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQ
200 210 220 230 240 250
260 270 280 290 300 310
pF1KE0 LVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIAN
::. : ::::.:::::::::..:. :::::: :.: : .:. ::::::..:. . ..
NP_001 LVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVG
260 270 280 290 300 310
320 330 340 350 360 370
pF1KE0 KNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDV
.::::::: ::.. :: ::.:. ... : ::
NP_001 RNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKIPSAVPSFLLHPLPFSWAI
320 330 340 350 360 370
380 390
pF1KE0 IRHIRVINGRAVEA
>>NP_005521 (OMIM: 601149) isocitrate dehydrogenase [NAD (366 aa)
initn: 918 init1: 760 opt: 928 Z-score: 1140.1 bits: 219.7 E(85289): 9.1e-57
Smith-Waterman score: 928; 42.2% identity (72.3% similar) in 372 aa overlap (18-384:3-363)
10 20 30 40 50 60
pF1KE0 MALKVATVAGSAAKAVLGPALLCRPWEVLGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMI
::: . . ..::: . : ... : :: .:::.:
NP_005 MAGPAWISKVSRLLGAFHNP-KQVTRGFT-------GGVQTVTLI
10 20 30
70 80 90 100 110
pF1KE0 PGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDI----RNAIMAIRRNRVALKG
::::::::. : ..: : .:...:: .:.. .: .. .:...:::
NP_005 PGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKG
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE0 NIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSS
..: . .: : : .:: ..:::::: : :. : : . :..:. .:::::::::.
NP_005 PLKT--PIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSG
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE0 LEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCC
.:: : :::.:.:.::.. : ::::.::. :... :..::::::::::...:::::: :
NP_005 IEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKC
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE0 REVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAG
:::: .: :..: .:.. ...:. :.::::.:::::::.:....::::.:: :.. .
NP_005 REVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPS
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE0 ANYG-HVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLAS
.: : . :.::.. ..:. .::.:..::::: ::.. ::: :. : ..:. :. : .:.
NP_005 GNIGANGVAIFESV-HGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFAT
280 290 300 310 320 330
360 370 380 390
pF1KE0 MDNENMHTPDIGGQGTTSEAIQDVIRHIRVINGRAVEA
. . . : :.::.. :. ... :...
NP_005 IKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD
340 350 360
>>XP_016877607 (OMIM: 601149) PREDICTED: isocitrate dehy (316 aa)
initn: 780 init1: 760 opt: 820 Z-score: 1008.8 bits: 195.2 E(85289): 1.9e-49
Smith-Waterman score: 820; 42.7% identity (74.5% similar) in 314 aa overlap (76-384:3-313)
50 60 70 80 90 100
pF1KE0 PPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDI----R
.: : .:...:: .:..
XP_016 MKIFDAAKAPIQWEERNVTAIQGPGGKWMIPS
10 20 30
110 120 130 140 150 160
pF1KE0 NAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDI
.: .. .:...::: ..: . .: : : .:: ..:::::: : :. : : . :.
XP_016 EAKESMDKNKMGLKGPLKT--PIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDV
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE0 DILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHK
.:. .:::::::::..:: : :::.:.:.::.. : ::::.::. :... :..::::::
XP_016 NIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHK
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE0 ANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVN
::::...:::::: ::::: .: :..: .:.. ...:. :.::::.:::::::.:..
XP_016 ANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILS
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE0 NVCAGLVGGPGLVAGANYG-HVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLK
..::::.:: :.. ..: : . :.::.. ..:. .::.:..::::: ::.. ::: :.
XP_016 DLCAGLIGGLGVTPSGNIGANGVAIFESV-HGTAPDIAGKDMANPTALLLSAVMMLRHMG
220 230 240 250 260
350 360 370 380 390
pF1KE0 LHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHIRVINGRAVEA
: ..:. :. : .:.. . . : :.::.. :. ... :...
XP_016 LFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD
270 280 290 300 310
>>XP_016877609 (OMIM: 601149) PREDICTED: isocitrate dehy (257 aa)
initn: 780 init1: 760 opt: 773 Z-score: 952.7 bits: 184.5 E(85289): 2.5e-46
Smith-Waterman score: 773; 47.2% identity (79.1% similar) in 254 aa overlap (132-384:2-254)
110 120 130 140 150 160
pF1KE0 NAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDI
: .:: ..:::::: : :. : : . :.
XP_016 MNLLLRKTFDLYANVRPCVSIEGYKTPYTDV
10 20 30
170 180 190 200 210 220
pF1KE0 DILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHK
.:. .:::::::::..:: : :::.:.:.::.. : ::::.::. :... :..::::::
XP_016 NIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHK
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE0 ANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVN
::::...:::::: ::::: .: :..: .:.. ...:. :.::::.:::::::.:..
XP_016 ANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILS
100 110 120 130 140 150
290 300 310 320 330 340
pF1KE0 NVCAGLVGGPGLVAGANYG-HVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLK
..::::.:: :.. ..: : . :.::.. ..:. .::.:..::::: ::.. ::: :.
XP_016 DLCAGLIGGLGVTPSGNIGANGVAIFESV-HGTAPDIAGKDMANPTALLLSAVMMLRHMG
160 170 180 190 200 210
350 360 370 380 390
pF1KE0 LHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHIRVINGRAVEA
: ..:. :. : .:.. . . : :.::.. :. ... :...
XP_016 LFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD
220 230 240 250
>>XP_005254393 (OMIM: 601149) PREDICTED: isocitrate dehy (257 aa)
initn: 780 init1: 760 opt: 773 Z-score: 952.7 bits: 184.5 E(85289): 2.5e-46
Smith-Waterman score: 773; 47.2% identity (79.1% similar) in 254 aa overlap (132-384:2-254)
110 120 130 140 150 160
pF1KE0 NAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDI
: .:: ..:::::: : :. : : . :.
XP_005 MNLLLRKTFDLYANVRPCVSIEGYKTPYTDV
10 20 30
170 180 190 200 210 220
pF1KE0 DILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHK
.:. .:::::::::..:: : :::.:.:.::.. : ::::.::. :... :..::::::
XP_005 NIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHK
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE0 ANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVN
::::...:::::: ::::: .: :..: .:.. ...:. :.::::.:::::::.:..
XP_005 ANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILS
100 110 120 130 140 150
290 300 310 320 330 340
pF1KE0 NVCAGLVGGPGLVAGANYG-HVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLK
..::::.:: :.. ..: : . :.::.. ..:. .::.:..::::: ::.. ::: :.
XP_005 DLCAGLIGGLGVTPSGNIGANGVAIFESV-HGTAPDIAGKDMANPTALLLSAVMMLRHMG
160 170 180 190 200 210
350 360 370 380 390
pF1KE0 LHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHIRVINGRAVEA
: ..:. :. : .:.. . . : :.::.. :. ... :...
XP_005 LFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD
220 230 240 250
393 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 10:51:31 2016 done: Thu Nov 3 10:51:32 2016
Total Scan time: 7.400 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]