Result of FASTA (ccds) for
pF1KE0422
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0422, 393 aa
1>>>pF1KE0422 393 - 393 aa - 393 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6179+/-0.00095; mu= 14.5604+/- 0.057
mean_var=61.2961+/-12.129, 0's: 0 Z-trim(103.7): 27 B-trim: 0 in 0/51
Lambda= 0.163817
statistics sampled from 7521 (7531) to 7521 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.602), E-opt: 0.2 (0.231), width: 16
Scan time: 2.520
The best scores are: opt bits E(32554)
CCDS14730.1 IDH3G gene_id:3421|Hs108|chrX ( 393) 2553 612.2 2.6e-175
CCDS44019.1 IDH3G gene_id:3421|Hs108|chrX ( 380) 2348 563.7 9.7e-161
CCDS13032.1 IDH3B gene_id:3420|Hs108|chr20 ( 385) 1169 285.1 7.5e-77
CCDS82594.1 IDH3B gene_id:3420|Hs108|chr20 ( 387) 1169 285.1 7.5e-77
CCDS13031.1 IDH3B gene_id:3420|Hs108|chr20 ( 383) 1144 279.2 4.5e-75
CCDS74696.1 IDH3B gene_id:3420|Hs108|chr20 ( 376) 1114 272.1 6e-73
CCDS10297.1 IDH3A gene_id:3419|Hs108|chr15 ( 366) 928 228.1 1e-59
>>CCDS14730.1 IDH3G gene_id:3421|Hs108|chrX (393 aa)
initn: 2553 init1: 2553 opt: 2553 Z-score: 3260.8 bits: 612.2 E(32554): 2.6e-175
Smith-Waterman score: 2553; 100.0% identity (100.0% similar) in 393 aa overlap (1-393:1-393)
10 20 30 40 50 60
pF1KE0 MALKVATVAGSAAKAVLGPALLCRPWEVLGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 MALKVATVAGSAAKAVLGPALLCRPWEVLGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNAIMAIRRNRVALKGNIET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 PGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNAIMAIRRNRVALKGNIET
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 NHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 NHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 SVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 SVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 ARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 HVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 HVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNEN
310 320 330 340 350 360
370 380 390
pF1KE0 MHTPDIGGQGTTSEAIQDVIRHIRVINGRAVEA
:::::::::::::::::::::::::::::::::
CCDS14 MHTPDIGGQGTTSEAIQDVIRHIRVINGRAVEA
370 380 390
>>CCDS44019.1 IDH3G gene_id:3421|Hs108|chrX (380 aa)
initn: 2377 init1: 2348 opt: 2348 Z-score: 2999.2 bits: 563.7 E(32554): 9.7e-161
Smith-Waterman score: 2348; 99.2% identity (99.7% similar) in 364 aa overlap (1-364:1-364)
10 20 30 40 50 60
pF1KE0 MALKVATVAGSAAKAVLGPALLCRPWEVLGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MALKVATVAGSAAKAVLGPALLCRPWEVLGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNAIMAIRRNRVALKGNIET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 PGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNAIMAIRRNRVALKGNIET
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 NHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 NHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 SVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 HVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 HVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNEN
310 320 330 340 350 360
370 380 390
pF1KE0 MHTPDIGGQGTTSEAIQDVIRHIRVINGRAVEA
.. :
CCDS44 VRFPSHPTLLPRPVSPCSLL
370 380
>>CCDS13032.1 IDH3B gene_id:3420|Hs108|chr20 (385 aa)
initn: 1190 init1: 1010 opt: 1169 Z-score: 1493.2 bits: 285.1 E(32554): 7.5e-77
Smith-Waterman score: 1169; 54.6% identity (78.5% similar) in 335 aa overlap (53-384:47-381)
30 40 50 60 70 80
pF1KE0 CRPWEVLGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACV
: :::.::::.::::: :: ::. : :
CCDS13 AGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAV
20 30 40 50 60 70
90 100 110 120 130
pF1KE0 PVDFEEVHVS---SNADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSL
::.:.: :.: . :.:: ..... ....:.::. :.:.: . : . :: .:
CCDS13 PVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRKL
80 90 100 110 120 130
140 150 160 170 180 190
pF1KE0 DLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLR
::.:::.: ::::: .:::...:..:.::.::::::::::::. ::.: :::.:.::: :
CCDS13 DLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQR
140 150 160 170 180 190
200 210 220 230 240 250
pF1KE0 IAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQ
::..:: : ..:: ::::::::::::::::::::::.::: ::.: ::.::.:: ::
CCDS13 IAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQ
200 210 220 230 240 250
260 270 280 290 300 310
pF1KE0 LVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIAN
::. : ::::.:::::::::..:. :::::: :.: : .:. ::::::..:. . ..
CCDS13 LVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVG
260 270 280 290 300 310
320 330 340 350 360 370
pF1KE0 KNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDV
.::::::: ::.. :: ::.:. ... : :: . ...: :.:: .::.. :..:
CCDS13 RNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKSV
320 330 340 350 360 370
380 390
pF1KE0 IRHIRVINGRAVEA
: :..
CCDS13 IGHLQTKGS
380
>>CCDS82594.1 IDH3B gene_id:3420|Hs108|chr20 (387 aa)
initn: 1190 init1: 1010 opt: 1169 Z-score: 1493.2 bits: 285.1 E(32554): 7.5e-77
Smith-Waterman score: 1169; 54.6% identity (78.5% similar) in 335 aa overlap (53-384:47-381)
30 40 50 60 70 80
pF1KE0 CRPWEVLGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACV
: :::.::::.::::: :: ::. : :
CCDS82 AGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAV
20 30 40 50 60 70
90 100 110 120 130
pF1KE0 PVDFEEVHVS---SNADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSL
::.:.: :.: . :.:: ..... ....:.::. :.:.: . : . :: .:
CCDS82 PVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRKL
80 90 100 110 120 130
140 150 160 170 180 190
pF1KE0 DLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLR
::.:::.: ::::: .:::...:..:.::.::::::::::::. ::.: :::.:.::: :
CCDS82 DLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQR
140 150 160 170 180 190
200 210 220 230 240 250
pF1KE0 IAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQ
::..:: : ..:: ::::::::::::::::::::::.::: ::.: ::.::.:: ::
CCDS82 IAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQ
200 210 220 230 240 250
260 270 280 290 300 310
pF1KE0 LVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIAN
::. : ::::.:::::::::..:. :::::: :.: : .:. ::::::..:. . ..
CCDS82 LVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVG
260 270 280 290 300 310
320 330 340 350 360 370
pF1KE0 KNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDV
.::::::: ::.. :: ::.:. ... : :: . ...: :.:: .::.. :..:
CCDS82 RNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKSV
320 330 340 350 360 370
380 390
pF1KE0 IRHIRVINGRAVEA
: :..
CCDS82 IGHLQTKGSNL
380
>>CCDS13031.1 IDH3B gene_id:3420|Hs108|chr20 (383 aa)
initn: 1174 init1: 994 opt: 1144 Z-score: 1461.3 bits: 279.2 E(32554): 4.5e-75
Smith-Waterman score: 1144; 54.4% identity (77.3% similar) in 331 aa overlap (53-380:47-377)
30 40 50 60 70 80
pF1KE0 CRPWEVLGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACV
: :::.::::.::::: :: ::. : :
CCDS13 AGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAV
20 30 40 50 60 70
90 100 110 120 130
pF1KE0 PVDFEEVHVS---SNADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSL
::.:.: :.: . :.:: ..... ....:.::. :.:.: . : . :: .:
CCDS13 PVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRKL
80 90 100 110 120 130
140 150 160 170 180 190
pF1KE0 DLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLR
::.:::.: ::::: .:::...:..:.::.::::::::::::. ::.: :::.:.::: :
CCDS13 DLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQR
140 150 160 170 180 190
200 210 220 230 240 250
pF1KE0 IAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQ
::..:: : ..:: ::::::::::::::::::::::.::: ::.: ::.::.:: ::
CCDS13 IAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQ
200 210 220 230 240 250
260 270 280 290 300 310
pF1KE0 LVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIAN
::. : ::::.:::::::::..:. :::::: :.: : .:. ::::::..:. . ..
CCDS13 LVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVG
260 270 280 290 300 310
320 330 340 350 360 370
pF1KE0 KNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDV
.::::::: ::.. :: ::.:. ... : :: . ...: :.:: .: . . :
CCDS13 RNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTSDMGGYATCHDFTEAV
320 330 340 350 360 370
380 390
pF1KE0 IRHIRVINGRAVEA
:
CCDS13 IAALPHP
380
>>CCDS74696.1 IDH3B gene_id:3420|Hs108|chr20 (376 aa)
initn: 1144 init1: 964 opt: 1114 Z-score: 1423.1 bits: 272.1 E(32554): 6e-73
Smith-Waterman score: 1114; 57.1% identity (79.5% similar) in 303 aa overlap (53-352:47-349)
30 40 50 60 70 80
pF1KE0 CRPWEVLGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACV
: :::.::::.::::: :: ::. : :
CCDS74 AGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAV
20 30 40 50 60 70
90 100 110 120 130
pF1KE0 PVDFEEVHVS---SNADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSL
::.:.: :.: . :.:: ..... ....:.::. :.:.: . : . :: .:
CCDS74 PVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRKL
80 90 100 110 120 130
140 150 160 170 180 190
pF1KE0 DLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLR
::.:::.: ::::: .:::...:..:.::.::::::::::::. ::.: :::.:.::: :
CCDS74 DLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQR
140 150 160 170 180 190
200 210 220 230 240 250
pF1KE0 IAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQ
::..:: : ..:: ::::::::::::::::::::::.::: ::.: ::.::.:: ::
CCDS74 IAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQ
200 210 220 230 240 250
260 270 280 290 300 310
pF1KE0 LVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIAN
::. : ::::.:::::::::..:. :::::: :.: : .:. ::::::..:. . ..
CCDS74 LVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVG
260 270 280 290 300 310
320 330 340 350 360 370
pF1KE0 KNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDV
.::::::: ::.. :: ::.:. ... : ::
CCDS74 RNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKIPSAVPSFLLHPLPFSWAI
320 330 340 350 360 370
380 390
pF1KE0 IRHIRVINGRAVEA
>>CCDS10297.1 IDH3A gene_id:3419|Hs108|chr15 (366 aa)
initn: 918 init1: 760 opt: 928 Z-score: 1185.8 bits: 228.1 E(32554): 1e-59
Smith-Waterman score: 928; 42.2% identity (72.3% similar) in 372 aa overlap (18-384:3-363)
10 20 30 40 50 60
pF1KE0 MALKVATVAGSAAKAVLGPALLCRPWEVLGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMI
::: . . ..::: . : ... : :: .:::.:
CCDS10 MAGPAWISKVSRLLGAFHNP-KQVTRGFT-------GGVQTVTLI
10 20 30
70 80 90 100 110
pF1KE0 PGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDI----RNAIMAIRRNRVALKG
::::::::. : ..: : .:...:: .:.. .: .. .:...:::
CCDS10 PGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKG
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE0 NIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSS
..: . .: : : .:: ..:::::: : :. : : . :..:. .:::::::::.
CCDS10 PLKT--PIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSG
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE0 LEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCC
.:: : :::.:.:.::.. : ::::.::. :... :..::::::::::...:::::: :
CCDS10 IEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKC
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE0 REVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAG
:::: .: :..: .:.. ...:. :.::::.:::::::.:....::::.:: :.. .
CCDS10 REVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPS
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE0 ANYG-HVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLAS
.: : . :.::.. ..:. .::.:..::::: ::.. ::: :. : ..:. :. : .:.
CCDS10 GNIGANGVAIFESV-HGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFAT
280 290 300 310 320 330
360 370 380 390
pF1KE0 MDNENMHTPDIGGQGTTSEAIQDVIRHIRVINGRAVEA
. . . : :.::.. :. ... :...
CCDS10 IKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD
340 350 360
393 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 10:51:31 2016 done: Thu Nov 3 10:51:31 2016
Total Scan time: 2.520 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]