Result of FASTA (omim) for
pF1KE0336
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0336, 488 aa
1>>>pF1KE0336 488 - 488 aa - 488 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3939+/-0.000441; mu= 16.9395+/- 0.027
mean_var=63.1530+/-13.251, 0's: 0 Z-trim(108.9): 41 B-trim: 0 in 0/46
Lambda= 0.161390
statistics sampled from 16987 (17009) to 16987 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.541), E-opt: 0.2 (0.199), width: 16
Scan time: 6.330
The best scores are: opt bits E(85289)
NP_077010 (OMIM: 607143,607144) dol-P-Man:Man(7)Gl ( 488) 3254 767.0 0
XP_016884426 (OMIM: 607143,607144) PREDICTED: dol- ( 441) 2770 654.2 2.1e-187
XP_016884425 (OMIM: 607143,607144) PREDICTED: dol- ( 447) 2770 654.2 2.1e-187
XP_011528673 (OMIM: 607143,607144) PREDICTED: dol- ( 352) 2231 528.7 1e-149
NP_004846 (OMIM: 604122) GPI mannosyltransferase 3 ( 554) 295 78.0 7.6e-14
XP_016878219 (OMIM: 604122) PREDICTED: GPI mannosy ( 421) 286 75.9 2.5e-13
XP_011520539 (OMIM: 604122) PREDICTED: GPI mannosy ( 421) 286 75.9 2.5e-13
XP_016878220 (OMIM: 604122) PREDICTED: GPI mannosy ( 421) 286 75.9 2.5e-13
XP_005254852 (OMIM: 604122) PREDICTED: GPI mannosy ( 393) 282 74.9 4.6e-13
XP_011520538 (OMIM: 604122) PREDICTED: GPI mannosy ( 519) 282 75.0 5.8e-13
XP_016878221 (OMIM: 604122) PREDICTED: GPI mannosy ( 378) 172 49.3 2.3e-05
XP_011520537 (OMIM: 604122) PREDICTED: GPI mannosy ( 539) 172 49.4 3.1e-05
>>NP_077010 (OMIM: 607143,607144) dol-P-Man:Man(7)GlcNAc (488 aa)
initn: 3254 init1: 3254 opt: 3254 Z-score: 4093.9 bits: 767.0 E(85289): 0
Smith-Waterman score: 3254; 100.0% identity (100.0% similar) in 488 aa overlap (1-488:1-488)
10 20 30 40 50 60
pF1KE0 MAGKGSSGRRPLLLGLLVAVATVHLVICPYTKVEESFNLQATHDLLYHWQDLEQYDHLEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 MAGKGSSGRRPLLLGLLVAVATVHLVICPYTKVEESFNLQATHDLLYHWQDLEQYDHLEF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PGVVPRTFLGPVVIAVFSSPAVYVLSLLEMSKFYSQLIVRGVLGLGVIFGLWTLQKEVRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 PGVVPRTFLGPVVIAVFSSPAVYVLSLLEMSKFYSQLIVRGVLGLGVIFGLWTLQKEVRR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 HFGAMVATMFCWVTAMQFHLMFYCTRTLPNVLALPVVLLALAAWLRHEWARFIWLSAFAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 HFGAMVATMFCWVTAMQFHLMFYCTRTLPNVLALPVVLLALAAWLRHEWARFIWLSAFAI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 IVFRVELCLFLGLLLLLALGNRKVSVVRALRHAVPAGILCLGLTVAVDSYFWRQLTWPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 IVFRVELCLFLGLLLLLALGNRKVSVVRALRHAVPAGILCLGLTVAVDSYFWRQLTWPEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 KVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLLFIPLGLVDRRTHAPTVLALGFMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 KVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLLFIPLGLVDRRTHAPTVLALGFMA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 LYSLLPHKELRFIIYAFPMLNITAARGCSYLLNNYKKSWLYKAGSLLVIGHLVVNAAYSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 LYSLLPHKELRFIIYAFPMLNITAARGCSYLLNNYKKSWLYKAGSLLVIGHLVVNAAYSA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 TALYVSHFNYPGGVAMQRLHQLVPPQTDVLLHIDVAAAQTGVSRFLQVNSAWRYDKREDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 TALYVSHFNYPGGVAMQRLHQLVPPQTDVLLHIDVAAAQTGVSRFLQVNSAWRYDKREDV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 QPGTGMLAYTHILMEAAPGLLALYRDTHRVLASVVGTTGVSLNLTQLPPFNVHLQTKLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 QPGTGMLAYTHILMEAAPGLLALYRDTHRVLASVVGTTGVSLNLTQLPPFNVHLQTKLVL
430 440 450 460 470 480
pF1KE0 LERLPRPS
::::::::
NP_077 LERLPRPS
>>XP_016884426 (OMIM: 607143,607144) PREDICTED: dol-P-Ma (441 aa)
initn: 2796 init1: 2770 opt: 2770 Z-score: 3485.6 bits: 654.2 E(85289): 2.1e-187
Smith-Waterman score: 2770; 99.3% identity (99.5% similar) in 416 aa overlap (1-416:1-416)
10 20 30 40 50 60
pF1KE0 MAGKGSSGRRPLLLGLLVAVATVHLVICPYTKVEESFNLQATHDLLYHWQDLEQYDHLEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGKGSSGRRPLLLGLLVAVATVHLVICPYTKVEESFNLQATHDLLYHWQDLEQYDHLEF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PGVVPRTFLGPVVIAVFSSPAVYVLSLLEMSKFYSQLIVRGVLGLGVIFGLWTLQKEVRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGVVPRTFLGPVVIAVFSSPAVYVLSLLEMSKFYSQLIVRGVLGLGVIFGLWTLQKEVRR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 HFGAMVATMFCWVTAMQFHLMFYCTRTLPNVLALPVVLLALAAWLRHEWARFIWLSAFAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HFGAMVATMFCWVTAMQFHLMFYCTRTLPNVLALPVVLLALAAWLRHEWARFIWLSAFAI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 IVFRVELCLFLGLLLLLALGNRKVSVVRALRHAVPAGILCLGLTVAVDSYFWRQLTWPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVFRVELCLFLGLLLLLALGNRKVSVVRALRHAVPAGILCLGLTVAVDSYFWRQLTWPEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 KVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLLFIPLGLVDRRTHAPTVLALGFMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLLFIPLGLVDRRTHAPTVLALGFMA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 LYSLLPHKELRFIIYAFPMLNITAARGCSYLLNNYKKSWLYKAGSLLVIGHLVVNAAYSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYSLLPHKELRFIIYAFPMLNITAARGCSYLLNNYKKSWLYKAGSLLVIGHLVVNAAYSA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 TALYVSHFNYPGGVAMQRLHQLVPPQTDVLLHIDVAAAQTGVSRFLQVNSAWRYDKREDV
:::::::::::::::::::::::::::::::::::::::::::::::::::: . :
XP_016 TALYVSHFNYPGGVAMQRLHQLVPPQTDVLLHIDVAAAQTGVSRFLQVNSAWSFPKSLNK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 QPGTGMLAYTHILMEAAPGLLALYRDTHRVLASVVGTTGVSLNLTQLPPFNVHLQTKLVL
XP_016 RKTRTVKPQSSDVINNNKKED
430 440
>>XP_016884425 (OMIM: 607143,607144) PREDICTED: dol-P-Ma (447 aa)
initn: 2769 init1: 2769 opt: 2770 Z-score: 3485.5 bits: 654.2 E(85289): 2.1e-187
Smith-Waterman score: 2770; 95.7% identity (97.3% similar) in 437 aa overlap (1-437:1-432)
10 20 30 40 50 60
pF1KE0 MAGKGSSGRRPLLLGLLVAVATVHLVICPYTKVEESFNLQATHDLLYHWQDLEQYDHLEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGKGSSGRRPLLLGLLVAVATVHLVICPYTKVEESFNLQATHDLLYHWQDLEQYDHLEF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PGVVPRTFLGPVVIAVFSSPAVYVLSLLEMSKFYSQLIVRGVLGLGVIFGLWTLQKEVRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGVVPRTFLGPVVIAVFSSPAVYVLSLLEMSKFYSQLIVRGVLGLGVIFGLWTLQKEVRR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 HFGAMVATMFCWVTAMQFHLMFYCTRTLPNVLALPVVLLALAAWLRHEWARFIWLSAFAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HFGAMVATMFCWVTAMQFHLMFYCTRTLPNVLALPVVLLALAAWLRHEWARFIWLSAFAI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 IVFRVELCLFLGLLLLLALGNRKVSVVRALRHAVPAGILCLGLTVAVDSYFWRQLTWPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVFRVELCLFLGLLLLLALGNRKVSVVRALRHAVPAGILCLGLTVAVDSYFWRQLTWPEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 KVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLLFIPLGLVDRRTHAPTVLALGFMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLLFIPLGLVDRRTHAPTVLALGFMA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 LYSLLPHKELRFIIYAFPMLNITAARGCSYLLNNYKKSWLYKAGSLLVIGHLVVNAAYSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYSLLPHKELRFIIYAFPMLNITAARGCSYLLNNYKKSWLYKAGSLLVIGHLVVNAAYSA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 TALYVSHFNYPGGVAMQRLHQLVPPQTDVLLHIDVAAAQTGVSRFLQVNSAWRYDKREDV
::::::::::::::::::::::::::::::::::::::::::::::::::::: .
XP_016 TALYVSHFNYPGGVAMQRLHQLVPPQTDVLLHIDVAAAQTGVSRFLQVNSAWRVSL---C
370 380 390 400 410
430 440 450 460 470 480
pF1KE0 QPGTGMLAYTHILMEAAPGLLALYRDTHRVLASVVGTTGVSLNLTQLPPFNVHLQTKLVL
.::.. : : . . .:
XP_016 RPGSS--AVTSLQLTTASTSQAQVILPPQPPE
420 430 440
>>XP_011528673 (OMIM: 607143,607144) PREDICTED: dol-P-Ma (352 aa)
initn: 2231 init1: 2231 opt: 2231 Z-score: 2808.8 bits: 528.7 E(85289): 1e-149
Smith-Waterman score: 2231; 100.0% identity (100.0% similar) in 331 aa overlap (1-331:1-331)
10 20 30 40 50 60
pF1KE0 MAGKGSSGRRPLLLGLLVAVATVHLVICPYTKVEESFNLQATHDLLYHWQDLEQYDHLEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAGKGSSGRRPLLLGLLVAVATVHLVICPYTKVEESFNLQATHDLLYHWQDLEQYDHLEF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PGVVPRTFLGPVVIAVFSSPAVYVLSLLEMSKFYSQLIVRGVLGLGVIFGLWTLQKEVRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGVVPRTFLGPVVIAVFSSPAVYVLSLLEMSKFYSQLIVRGVLGLGVIFGLWTLQKEVRR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 HFGAMVATMFCWVTAMQFHLMFYCTRTLPNVLALPVVLLALAAWLRHEWARFIWLSAFAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HFGAMVATMFCWVTAMQFHLMFYCTRTLPNVLALPVVLLALAAWLRHEWARFIWLSAFAI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 IVFRVELCLFLGLLLLLALGNRKVSVVRALRHAVPAGILCLGLTVAVDSYFWRQLTWPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVFRVELCLFLGLLLLLALGNRKVSVVRALRHAVPAGILCLGLTVAVDSYFWRQLTWPEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 KVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLLFIPLGLVDRRTHAPTVLALGFMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLLFIPLGLVDRRTHAPTVLALGFMA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 LYSLLPHKELRFIIYAFPMLNITAARGCSYLLNNYKKSWLYKAGSLLVIGHLVVNAAYSA
:::::::::::::::::::::::::::::::
XP_011 LYSLLPHKELRFIIYAFPMLNITAARGCSYLWRRNAEAAPAGAPPDRRPSAH
310 320 330 340 350
370 380 390 400 410 420
pF1KE0 TALYVSHFNYPGGVAMQRLHQLVPPQTDVLLHIDVAAAQTGVSRFLQVNSAWRYDKREDV
>>NP_004846 (OMIM: 604122) GPI mannosyltransferase 3 [Ho (554 aa)
initn: 179 init1: 75 opt: 295 Z-score: 369.6 bits: 78.0 E(85289): 7.6e-14
Smith-Waterman score: 310; 26.2% identity (56.3% similar) in 378 aa overlap (6-359:49-403)
10 20 30
pF1KE0 MAGKGSSGRRPLLLGLLVAVATVHLVICPYT-KVE
:. :: ::: ...:.. . ..
NP_004 LTLHGLQNRSHGKIKLRKRKSTLYFNTQEKSARRRGDLLG-----ENIYLLLFTIALRIL
20 30 40 50 60 70
40 50 60 70 80
pF1KE0 ESFNLQATHDLLYHWQDLEQYDHLEFP-GVVP-------RTFLGPVVIAVFSSPAVY-VL
. : .:.. .::.:: :. : : . :.. :...: ..: .:
NP_004 NCFLVQTSFVPDEYWQSLEVSHHMVFNYGYLTWEWTERLRSYTYPLIFA-----SIYKIL
80 90 100 110 120
90 100 110 120 130
pF1KE0 SLLEMSKFYSQLIV------RGVLGLGVIFGLWTLQKEVRRHFGAMVATMFCWVTAMQFH
:: .: ::.. ...:. . :..:.:... . : . .:: . . .
NP_004 HLL--GKDSVQLLIWIPRLAQALLSAVADVRLYSLMKQLENQEVARWV-FFCQLCS--WF
130 140 150 160 170 180
140 150 160 170 180 190
pF1KE0 LMFYCTRTLPNVLALPVVLLALAAW-----LRHEWARFIWLSAFAIIVFRVELCLFLGLL
. ::::: :.. ....:: . . ... : :.:.:. . . :. ::
NP_004 TWYCCTRTLTNTMETVLTIIALFYYPLEGSKSMNSVKYSSLVALAFIIRPTAVILWTPLL
190 200 210 220 230 240
200 210 220 230 240 250
pF1KE0 LL-LALGNRKVSVVRALRHAVPAGILCLGLTVAVDSYFWRQLTWPEGKVLWYNTVLNKSS
. . ::.... :.: .:.:.. :.:.. .: :. : : . . : .:.. : ..
NP_004 FRHFCQEPRKLDLI--LHHFLPVGFVTLSLSLMIDRIFFGQWTLVQFNFLKFNVLQNWGT
250 260 270 280 290 300
260 270 280 290 300 310
pF1KE0 NWGTSPLLWYFYSALPRGLGCSLLFIPLG--LVDRRTHAPTVLALGFMALYSLLPHKELR
.:. : ::: ...: :: : :. : :. .: . : .: . .::.: :::.:
NP_004 FYGSHPWHWYFSQGFPVILGTHLPFFIHGCYLAPKRYRILLVTVLWTLLVYSMLSHKEFR
310 320 330 340 350 360
320 330 340 350 360 370
pF1KE0 FIIYAFPMLNITAARGCSYLLNNYKKSWLYKAGSLLVIGHLVVNAAYSATALYVSHFNYP
:: ..:. . :.: :.. : .: : :.: ...: . : :.
NP_004 FIYPVLPFCMVF----CGYSLTHLK-TWKKPALSFLFLSNLFL-ALYTGLVHQRGTLDVM
370 380 390 400 410
380 390 400 410 420 430
pF1KE0 GGVAMQRLHQLVPPQTDVLLHIDVAAAQTGVSRFLQVNSAWRYDKREDVQPGTGMLAYTH
NP_004 SHIQKVCYNNPNKSSASIFIMMPCHSTPYYSHVHCPLPMRFLQCPPDLTGKSHYLDEADV
420 430 440 450 460 470
>>XP_016878219 (OMIM: 604122) PREDICTED: GPI mannosyltra (421 aa)
initn: 179 init1: 75 opt: 286 Z-score: 360.1 bits: 75.9 E(85289): 2.5e-13
Smith-Waterman score: 286; 28.0% identity (59.5% similar) in 257 aa overlap (111-359:25-270)
90 100 110 120 130 140
pF1KE0 AVYVLSLLEMSKFYSQLIVRGVLGLGVIFGLWTLQKEVRRHFGAMVATMFCWVTAMQFHL
:..:.:... . : . .:: . . .
XP_016 MQSKQKIWIPRLAQALLSAVADVRLYSLMKQLENQEVARWV-FFCQLCS--WFT
10 20 30 40 50
150 160 170 180 190
pF1KE0 MFYCTRTLPNVLALPVVLLALAAW-----LRHEWARFIWLSAFAIIVFRVELCLFLGLLL
. ::::: :.. ....:: . . ... : :.:.:. . . :. ::.
XP_016 WYCCTRTLTNTMETVLTIIALFYYPLEGSKSMNSVKYSSLVALAFIIRPTAVILWTPLLF
60 70 80 90 100 110
200 210 220 230 240 250
pF1KE0 L-LALGNRKVSVVRALRHAVPAGILCLGLTVAVDSYFWRQLTWPEGKVLWYNTVLNKSSN
. ::.... :.: .:.:.. :.:.. .: :. : : . . : .:.. : ..
XP_016 RHFCQEPRKLDLI--LHHFLPVGFVTLSLSLMIDRIFFGQWTLVQFNFLKFNVLQNWGTF
120 130 140 150 160
260 270 280 290 300 310
pF1KE0 WGTSPLLWYFYSALPRGLGCSLLFIPLG--LVDRRTHAPTVLALGFMALYSLLPHKELRF
.:. : ::: ...: :: : :. : :. .: . : .: . .::.: :::.::
XP_016 YGSHPWHWYFSQGFPVILGTHLPFFIHGCYLAPKRYRILLVTVLWTLLVYSMLSHKEFRF
170 180 190 200 210 220
320 330 340 350 360 370
pF1KE0 IIYAFPMLNITAARGCSYLLNNYKKSWLYKAGSLLVIGHLVVNAAYSATALYVSHFNYPG
: ..:. . :.: :.. : .: : :.: ...: . : :.
XP_016 IYPVLPFCMVF----CGYSLTHLK-TWKKPALSFLFLSNLFL-ALYTGLVHQRGTLDVMS
230 240 250 260 270 280
380 390 400 410 420 430
pF1KE0 GVAMQRLHQLVPPQTDVLLHIDVAAAQTGVSRFLQVNSAWRYDKREDVQPGTGMLAYTHI
XP_016 HIQKVCYNNPNKSSASIFIMMPCHSTPYYSHVHCPLPMRFLQCPPDLTGKSHYLDEADVF
290 300 310 320 330 340
>>XP_011520539 (OMIM: 604122) PREDICTED: GPI mannosyltra (421 aa)
initn: 179 init1: 75 opt: 286 Z-score: 360.1 bits: 75.9 E(85289): 2.5e-13
Smith-Waterman score: 286; 28.0% identity (59.5% similar) in 257 aa overlap (111-359:25-270)
90 100 110 120 130 140
pF1KE0 AVYVLSLLEMSKFYSQLIVRGVLGLGVIFGLWTLQKEVRRHFGAMVATMFCWVTAMQFHL
:..:.:... . : . .:: . . .
XP_011 MQSKQKIWIPRLAQALLSAVADVRLYSLMKQLENQEVARWV-FFCQLCS--WFT
10 20 30 40 50
150 160 170 180 190
pF1KE0 MFYCTRTLPNVLALPVVLLALAAW-----LRHEWARFIWLSAFAIIVFRVELCLFLGLLL
. ::::: :.. ....:: . . ... : :.:.:. . . :. ::.
XP_011 WYCCTRTLTNTMETVLTIIALFYYPLEGSKSMNSVKYSSLVALAFIIRPTAVILWTPLLF
60 70 80 90 100 110
200 210 220 230 240 250
pF1KE0 L-LALGNRKVSVVRALRHAVPAGILCLGLTVAVDSYFWRQLTWPEGKVLWYNTVLNKSSN
. ::.... :.: .:.:.. :.:.. .: :. : : . . : .:.. : ..
XP_011 RHFCQEPRKLDLI--LHHFLPVGFVTLSLSLMIDRIFFGQWTLVQFNFLKFNVLQNWGTF
120 130 140 150 160
260 270 280 290 300 310
pF1KE0 WGTSPLLWYFYSALPRGLGCSLLFIPLG--LVDRRTHAPTVLALGFMALYSLLPHKELRF
.:. : ::: ...: :: : :. : :. .: . : .: . .::.: :::.::
XP_011 YGSHPWHWYFSQGFPVILGTHLPFFIHGCYLAPKRYRILLVTVLWTLLVYSMLSHKEFRF
170 180 190 200 210 220
320 330 340 350 360 370
pF1KE0 IIYAFPMLNITAARGCSYLLNNYKKSWLYKAGSLLVIGHLVVNAAYSATALYVSHFNYPG
: ..:. . :.: :.. : .: : :.: ...: . : :.
XP_011 IYPVLPFCMVF----CGYSLTHLK-TWKKPALSFLFLSNLFL-ALYTGLVHQRGTLDVMS
230 240 250 260 270 280
380 390 400 410 420 430
pF1KE0 GVAMQRLHQLVPPQTDVLLHIDVAAAQTGVSRFLQVNSAWRYDKREDVQPGTGMLAYTHI
XP_011 HIQKVCYNNPNKSSASIFIMMPCHSTPYYSHVHCPLPMRFLQCPPDLTGKSHYLDEADVF
290 300 310 320 330 340
>>XP_016878220 (OMIM: 604122) PREDICTED: GPI mannosyltra (421 aa)
initn: 179 init1: 75 opt: 286 Z-score: 360.1 bits: 75.9 E(85289): 2.5e-13
Smith-Waterman score: 286; 28.0% identity (59.5% similar) in 257 aa overlap (111-359:25-270)
90 100 110 120 130 140
pF1KE0 AVYVLSLLEMSKFYSQLIVRGVLGLGVIFGLWTLQKEVRRHFGAMVATMFCWVTAMQFHL
:..:.:... . : . .:: . . .
XP_016 MQSKQKIWIPRLAQALLSAVADVRLYSLMKQLENQEVARWV-FFCQLCS--WFT
10 20 30 40 50
150 160 170 180 190
pF1KE0 MFYCTRTLPNVLALPVVLLALAAW-----LRHEWARFIWLSAFAIIVFRVELCLFLGLLL
. ::::: :.. ....:: . . ... : :.:.:. . . :. ::.
XP_016 WYCCTRTLTNTMETVLTIIALFYYPLEGSKSMNSVKYSSLVALAFIIRPTAVILWTPLLF
60 70 80 90 100 110
200 210 220 230 240 250
pF1KE0 L-LALGNRKVSVVRALRHAVPAGILCLGLTVAVDSYFWRQLTWPEGKVLWYNTVLNKSSN
. ::.... :.: .:.:.. :.:.. .: :. : : . . : .:.. : ..
XP_016 RHFCQEPRKLDLI--LHHFLPVGFVTLSLSLMIDRIFFGQWTLVQFNFLKFNVLQNWGTF
120 130 140 150 160
260 270 280 290 300 310
pF1KE0 WGTSPLLWYFYSALPRGLGCSLLFIPLG--LVDRRTHAPTVLALGFMALYSLLPHKELRF
.:. : ::: ...: :: : :. : :. .: . : .: . .::.: :::.::
XP_016 YGSHPWHWYFSQGFPVILGTHLPFFIHGCYLAPKRYRILLVTVLWTLLVYSMLSHKEFRF
170 180 190 200 210 220
320 330 340 350 360 370
pF1KE0 IIYAFPMLNITAARGCSYLLNNYKKSWLYKAGSLLVIGHLVVNAAYSATALYVSHFNYPG
: ..:. . :.: :.. : .: : :.: ...: . : :.
XP_016 IYPVLPFCMVF----CGYSLTHLK-TWKKPALSFLFLSNLFL-ALYTGLVHQRGTLDVMS
230 240 250 260 270 280
380 390 400 410 420 430
pF1KE0 GVAMQRLHQLVPPQTDVLLHIDVAAAQTGVSRFLQVNSAWRYDKREDVQPGTGMLAYTHI
XP_016 HIQKVCYNNPNKSSASIFIMMPCHSTPYYSHVHCPLPMRFLQCPPDLTGKSHYLDEADVF
290 300 310 320 330 340
>>XP_005254852 (OMIM: 604122) PREDICTED: GPI mannosyltra (393 aa)
initn: 179 init1: 75 opt: 282 Z-score: 355.6 bits: 74.9 E(85289): 4.6e-13
Smith-Waterman score: 282; 28.6% identity (58.8% similar) in 238 aa overlap (130-359:15-242)
100 110 120 130 140 150
pF1KE0 RGVLGLGVIFGLWTLQKEVRRHFGAMVATMFCWVTAMQFHLMFYCTRTLPNVLALPVVLL
:: . . . . ::::: :.. ....
XP_005 MKQLENQEVARWVFFCQLCS--WFTWYCCTRTLTNTMETVLTII
10 20 30 40
160 170 180 190 200 210
pF1KE0 ALAAW-----LRHEWARFIWLSAFAIIVFRVELCLFLGLLLL-LALGNRKVSVVRALRHA
:: . . ... : :.:.:. . . :. ::. . ::.... :.:
XP_005 ALFYYPLEGSKSMNSVKYSSLVALAFIIRPTAVILWTPLLFRHFCQEPRKLDLI--LHHF
50 60 70 80 90 100
220 230 240 250 260 270
pF1KE0 VPAGILCLGLTVAVDSYFWRQLTWPEGKVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLG
.:.:.. :.:.. .: :. : : . . : .:.. : .. .:. : ::: ...: ::
XP_005 LPVGFVTLSLSLMIDRIFFGQWTLVQFNFLKFNVLQNWGTFYGSHPWHWYFSQGFPVILG
110 120 130 140 150 160
280 290 300 310 320 330
pF1KE0 CSLLFIPLG--LVDRRTHAPTVLALGFMALYSLLPHKELRFIIYAFPMLNITAARGCSYL
: :. : :. .: . : .: . .::.: :::.::: ..:. . :.:
XP_005 THLPFFIHGCYLAPKRYRILLVTVLWTLLVYSMLSHKEFRFIYPVLPFCMVF----CGYS
170 180 190 200 210
340 350 360 370 380 390
pF1KE0 LNNYKKSWLYKAGSLLVIGHLVVNAAYSATALYVSHFNYPGGVAMQRLHQLVPPQTDVLL
:.. : .: : :.: ...: . : :.
XP_005 LTHLK-TWKKPALSFLFLSNLFL-ALYTGLVHQRGTLDVMSHIQKVCYNNPNKSSASIFI
220 230 240 250 260 270
>>XP_011520538 (OMIM: 604122) PREDICTED: GPI mannosyltra (519 aa)
initn: 179 init1: 75 opt: 282 Z-score: 353.7 bits: 75.0 E(85289): 5.8e-13
Smith-Waterman score: 282; 28.6% identity (58.8% similar) in 238 aa overlap (130-359:141-368)
100 110 120 130 140 150
pF1KE0 RGVLGLGVIFGLWTLQKEVRRHFGAMVATMFCWVTAMQFHLMFYCTRTLPNVLALPVVLL
:: . . . . ::::: :.. ....
XP_011 RLRSYTYPLIFASIYKILHLLGKDSVQLLFFCQLCS--WFTWYCCTRTLTNTMETVLTII
120 130 140 150 160
160 170 180 190 200 210
pF1KE0 ALAAW-----LRHEWARFIWLSAFAIIVFRVELCLFLGLLLL-LALGNRKVSVVRALRHA
:: . . ... : :.:.:. . . :. ::. . ::.... :.:
XP_011 ALFYYPLEGSKSMNSVKYSSLVALAFIIRPTAVILWTPLLFRHFCQEPRKLDLI--LHHF
170 180 190 200 210 220
220 230 240 250 260 270
pF1KE0 VPAGILCLGLTVAVDSYFWRQLTWPEGKVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLG
.:.:.. :.:.. .: :. : : . . : .:.. : .. .:. : ::: ...: ::
XP_011 LPVGFVTLSLSLMIDRIFFGQWTLVQFNFLKFNVLQNWGTFYGSHPWHWYFSQGFPVILG
230 240 250 260 270 280
280 290 300 310 320 330
pF1KE0 CSLLFIPLG--LVDRRTHAPTVLALGFMALYSLLPHKELRFIIYAFPMLNITAARGCSYL
: :. : :. .: . : .: . .::.: :::.::: ..:. . :.:
XP_011 THLPFFIHGCYLAPKRYRILLVTVLWTLLVYSMLSHKEFRFIYPVLPFCMVF----CGYS
290 300 310 320 330 340
340 350 360 370 380 390
pF1KE0 LNNYKKSWLYKAGSLLVIGHLVVNAAYSATALYVSHFNYPGGVAMQRLHQLVPPQTDVLL
:.. : .: : :.: ...: . : :.
XP_011 LTHLK-TWKKPALSFLFLSNLFL-ALYTGLVHQRGTLDVMSHIQKVCYNNPNKSSASIFI
350 360 370 380 390 400
488 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 15:22:54 2016 done: Thu Nov 3 15:22:55 2016
Total Scan time: 6.330 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]