Result of FASTA (omim) for
pF1KE0305
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0305, 652 aa
1>>>pF1KE0305 652 - 652 aa - 652 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.5253+/-0.00036; mu= 6.1672+/- 0.022
mean_var=255.9098+/-51.227, 0's: 0 Z-trim(121.7): 430 B-trim: 41 in 1/58
Lambda= 0.080173
statistics sampled from 38091 (38582) to 38091 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.776), E-opt: 0.2 (0.452), width: 16
Scan time: 13.680
The best scores are: opt bits E(85289)
NP_036204 (OMIM: 120577) complement component C1q ( 652) 4648 551.2 4.3e-156
XP_011525684 (OMIM: 604710,613177) PREDICTED: late (1554) 566 79.4 1.1e-13
XP_011525689 (OMIM: 604710,613177) PREDICTED: late (1421) 549 77.4 3.9e-13
XP_011525688 (OMIM: 604710,613177) PREDICTED: late (1436) 549 77.4 3.9e-13
XP_016882843 (OMIM: 604710,613177) PREDICTED: late (1438) 549 77.4 3.9e-13
XP_011525687 (OMIM: 604710,613177) PREDICTED: late (1478) 549 77.4 4e-13
XP_011525686 (OMIM: 604710,613177) PREDICTED: late (1480) 549 77.4 4e-13
XP_011525685 (OMIM: 604710,613177) PREDICTED: late (1522) 549 77.5 4.1e-13
XP_016882842 (OMIM: 604710,613177) PREDICTED: late (1549) 549 77.5 4.1e-13
NP_001036010 (OMIM: 604710,613177) latent-transfor (1557) 549 77.5 4.1e-13
NP_003564 (OMIM: 604710,613177) latent-transformin (1587) 549 77.5 4.2e-13
XP_016882841 (OMIM: 604710,613177) PREDICTED: late (1591) 549 77.5 4.2e-13
XP_011525683 (OMIM: 604710,613177) PREDICTED: late (1593) 549 77.5 4.2e-13
XP_011525682 (OMIM: 604710,613177) PREDICTED: late (1593) 549 77.5 4.2e-13
XP_011525681 (OMIM: 604710,613177) PREDICTED: late (1595) 549 77.5 4.2e-13
XP_011525680 (OMIM: 604710,613177) PREDICTED: late (1611) 549 77.5 4.2e-13
NP_001036009 (OMIM: 604710,613177) latent-transfor (1624) 549 77.5 4.3e-13
XP_011525679 (OMIM: 604710,613177) PREDICTED: late (1635) 549 77.5 4.3e-13
XP_011525678 (OMIM: 604710,613177) PREDICTED: late (1662) 549 77.5 4.3e-13
XP_011531163 (OMIM: 150390) PREDICTED: latent-tran (1632) 544 76.9 6.4e-13
XP_011531164 (OMIM: 150390) PREDICTED: latent-tran (1248) 540 76.3 7.3e-13
XP_016859599 (OMIM: 150390) PREDICTED: latent-tran (1639) 542 76.7 7.5e-13
NP_001159738 (OMIM: 150390) latent-transforming gr (1300) 540 76.3 7.5e-13
XP_016859597 (OMIM: 150390) PREDICTED: latent-tran (1681) 542 76.7 7.6e-13
XP_011531158 (OMIM: 150390) PREDICTED: latent-tran (1682) 542 76.7 7.6e-13
NP_001159737 (OMIM: 150390) latent-transforming gr (1342) 540 76.4 7.7e-13
NP_001159736 (OMIM: 150390) latent-transforming gr (1353) 540 76.4 7.7e-13
NP_000618 (OMIM: 150390) latent-transforming growt (1395) 540 76.4 7.9e-13
NP_001157738 (OMIM: 601216,602090,613097) latent-t (1139) 537 75.9 8.7e-13
XP_005264375 (OMIM: 150390) PREDICTED: latent-tran (1626) 540 76.4 8.8e-13
XP_011531162 (OMIM: 150390) PREDICTED: latent-tran (1666) 540 76.5 8.9e-13
XP_005264374 (OMIM: 150390) PREDICTED: latent-tran (1668) 540 76.5 8.9e-13
XP_011531161 (OMIM: 150390) PREDICTED: latent-tran (1669) 540 76.5 8.9e-13
XP_016859598 (OMIM: 150390) PREDICTED: latent-tran (1679) 540 76.5 9e-13
XP_011531159 (OMIM: 150390) PREDICTED: latent-tran (1680) 540 76.5 9e-13
XP_011531160 (OMIM: 150390) PREDICTED: latent-tran (1680) 540 76.5 9e-13
XP_011531157 (OMIM: 150390) PREDICTED: latent-tran (1720) 540 76.5 9.1e-13
NP_996826 (OMIM: 150390) latent-transforming growt (1721) 540 76.5 9.1e-13
XP_011531155 (OMIM: 150390) PREDICTED: latent-tran (1722) 540 76.5 9.1e-13
NP_066548 (OMIM: 601216,602090,613097) latent-tran (1256) 537 76.0 9.4e-13
XP_011543335 (OMIM: 601216,602090,613097) PREDICTE (1265) 537 76.0 9.4e-13
NP_001123616 (OMIM: 601216,602090,613097) latent-t (1303) 537 76.0 9.6e-13
XP_011543334 (OMIM: 601216,602090,613097) PREDICTE (1312) 537 76.0 9.6e-13
NP_065137 (OMIM: 606064) endosialin precursor [Hom ( 757) 526 74.5 1.6e-12
XP_016872833 (OMIM: 611115) PREDICTED: von Willebr ( 519) 522 73.8 1.7e-12
XP_011543119 (OMIM: 611115) PREDICTED: von Willebr ( 857) 522 74.1 2.4e-12
XP_006718525 (OMIM: 611115) PREDICTED: von Willebr ( 895) 522 74.1 2.5e-12
XP_006718523 (OMIM: 611115) PREDICTED: von Willebr ( 947) 522 74.1 2.6e-12
NP_689931 (OMIM: 611115) von Willebrand factor C a ( 955) 522 74.1 2.6e-12
NP_058634 (OMIM: 604633,614437) EGF-containing fib ( 443) 502 71.5 7.6e-12
>>NP_036204 (OMIM: 120577) complement component C1q rece (652 aa)
initn: 4648 init1: 4648 opt: 4648 Z-score: 2923.3 bits: 551.2 E(85289): 4.3e-156
Smith-Waterman score: 4648; 99.8% identity (99.8% similar) in 652 aa overlap (1-652:1-652)
10 20 30 40 50 60
pF1KE0 MATSMGLLLLLLLLLTQPGAGTGADTEAVVCVGTACYTAHSGKLSAAEAQNHCNQNGGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MATSMGLLLLLLLLLTQPGAGTGADTEAVVCVGTACYTAHSGKLSAAEAQNHCNQNGGNL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 ATVKSKEEAQHVQRVLAQLLRREAALTARMSKFWIGLQREKGKCLDPSLPLKGFSWVGGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ATVKSKEEAQHVQRVLAQLLRREAALTARMSKFWIGLQREKGKCLDPSLPLKGFSWVGGG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 EDTPYSNWHKELRNSCISKRCVSLLLDLSQPLLPSRLPKWSEGPCGSPGSPGSNIEGFVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EDTPYSNWHKELRNSCISKRCVSLLLDLSQPLLPSRLPKWSEGPCGSPGSPGSNIEGFVC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 KFSFKGMCRPLALGGPGQVTYTTPFQTTSSSLEAVPFASAANVACGEGDKDETQSHYFLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KFSFKGMCRPLALGGPGQVTYTTPFQTTSSSLEAVPFASAANVACGEGDKDETQSHYFLC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 KEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 ASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECVN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 TPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 DGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSCTMGPVSLGPPSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSCTMGPVSLGPPSGP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 PDEEDKGEKEGSTVPRAATASPTRGPEGTLKATPTTSRPSLSSDAPITSAPLKMLAPSGS
::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::
NP_036 PDEEDKGEKEGSTVPRAATASPTRGPEGTPKATPTTSRPSLSSDAPITSAPLKMLAPSGS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 PGVWREPSIHHATAASGPQEPAGGDSSVATQNNDGTDGQKLLLFYILGTVVAILLLLALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PGVWREPSIHHATAASGPQEPAGGDSSVATQNNDGTDGQKLLLFYILGTVVAILLLLALA
550 560 570 580 590 600
610 620 630 640 650
pF1KE0 LGLLVYRKRRAKREEKKEKKPQNAADSYSWVPERAESRAMENQYSPTPGTDC
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LGLLVYRKRRAKREEKKEKKPQNAADSYSWVPERAESRAMENQYSPTPGTDC
610 620 630 640 650
>>XP_011525684 (OMIM: 604710,613177) PREDICTED: latent-t (1554 aa)
initn: 260 init1: 260 opt: 566 Z-score: 367.0 bits: 79.4 E(85289): 1.1e-13
Smith-Waterman score: 566; 33.9% identity (57.0% similar) in 330 aa overlap (153-467:539-848)
130 140 150 160 170 180
pF1KE0 TPYSNWHKELRNSCISKRCVSLLLDLSQPLLPSRLPKWSEGPCGSPGSPGSNIEGFVCKF
::: .: :. :: ..:.:.. :.
XP_011 SRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPS-IPAWT-GPEIPESGPSSGM----CQR
510 520 530 540 550 560
190 200 210 220 230
pF1KE0 SFKGMCRP-LALGGPGQVTYT--TPFQTTSSSLEAVPFASAANVA--CGEGDKDETQSHY
. . .: : .. :. : . . :. . .. . . : :. : . :..
XP_011 NPQ-VCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPG-RCENSPGS
570 580 590 600 610 620
240 250 260 270 280 290
pF1KE0 FLCKEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDL
: : .: : : . :.. :. : :. ::::: : :..
XP_011 FRCVC-GPG-FRAGPRAAECLDVDE-CHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHG
630 640 650 660 670
300 310 320 330 340 350
pF1KE0 VTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDS-PC
..: . . :. :: : : : . .: .. : ::.:.: ... .: :::::.. :
XP_011 ASCQDVDECARSPPPCTYG-RCE-NTEG-SFQCVCPMGFQPNTAGSECEDVDECENHLAC
680 690 700 710 720 730
360 370 380 390 400 410
pF1KE0 -AQECVNTPGGFRCE-CWVGYEPGGPGEGACQDVDECALGRSPCA-QG-CTNTDGSFHCS
.:::::.::.:.:. : :.. .: : :::::. : ::. .: ::::.:::.::
XP_011 PGQECVNSPGSFQCRTCPSGHHL---HRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCS
740 750 760 770 780 790
420 430 440 450 460
pF1KE0 CEEGY-VLAGEDGTQCQDVDECVGPGGPLC--DSLCFNTQGSFHCGCLPGWVLAPNGVSC
: :: . .:. : : ::.::. : .: . :.::.::: : : ::. .: :.::
XP_011 CAPGYRAPSGRPGP-CADVNECL--EGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC
800 810 820 830 840
470 480 490 500 510 520
pF1KE0 TMGPVSLGPPSGPPDEEDKGEKEGSTVPRAATASPTRGPEGTLKATPTTSRPSLSSDAPI
XP_011 LDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRC
850 860 870 880 890 900
>--
initn: 211 init1: 185 opt: 510 Z-score: 332.0 bits: 73.0 E(85289): 9.4e-12
Smith-Waterman score: 510; 37.0% identity (54.0% similar) in 289 aa overlap (271-541:860-1120)
250 260 270 280 290 300
pF1KE0 KEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTC
:.. . :::: : : :: : ::..:
XP_011 SFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC
830 840 850 860 870 880
310 320 330 340 350
pF1KE0 ASRNPCSS-SP--CRGGATCVLGPHGKNYTC--RCPQGYQLDSSQLDCVDVDECQD-SP-
. . : .: : :. : .: .: : : ::. . . : ::::::. .:
XP_011 LDVDECRERGPALC-GSQRCENSPG--SYRCVRDCDPGYHA-GPEGTCDDVDECQEYGPE
890 900 910 920 930 940
360 370 380 390 400
pF1KE0 -C-AQECVNTPGGFRCE--CWVGYEPGGPGEGACQDVDECALGRSPCAQG--CTNTDGSF
: ::.: ::::..:: : ::.: :: :.::::::: .:: :. : : :::
XP_011 ICGAQRCENTPGSYRCTPACDPGYQPT-PG-GGCQDVDECR-NRSFCGAHAVCQNLPGSF
950 960 970 980 990 1000
410 420 430 440 450 460
pF1KE0 HCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC
.: :..:: : .:: .: ::.:: : .:: :..::: : : ::.
XP_011 QCLCDQGYEGA-RDGRHCVDVNECETLQGVCGAALCENVEGSFLCVC-------PNS---
1010 1020 1030 1040 1050
470 480 490 500 510 520
pF1KE0 TMGPVSLGPPSG---PPDEEDKGEKEGSTVPRAATAS--PTRGPEGTLKATPTTSRPSLS
: . : .: :: . . : :: :.: .. :.: : : :::
XP_011 ---PEEFDPMTGRCVPP-RTSAGTFPGSQ-PQAPASPVLPARPPP-----PPLPRRPSTP
1060 1070 1080 1090 1100
530 540 550 560 570 580
pF1KE0 SDAPITSAPLKMLAPSGSPGVWREPSIHHATAASGPQEPAGGDSSVATQNNDGTDGQKLL
..:. :. . ...:
XP_011 RQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEY
1110 1120 1130 1140 1150 1160
>>XP_011525689 (OMIM: 604710,613177) PREDICTED: latent-t (1421 aa)
initn: 260 init1: 260 opt: 549 Z-score: 356.8 bits: 77.4 E(85289): 3.9e-13
Smith-Waterman score: 566; 33.2% identity (51.1% similar) in 407 aa overlap (107-467:321-715)
80 90 100 110 120 130
pF1KE0 AQLLRREAALTARMSKFWIGLQREKGKCLDPSLPLKGF-SWVGG--GEDTPYSNWHKELR
: ::: .. .:.: :. : :. ..
XP_011 LPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNP
300 310 320 330 340 350
140 150 160 170
pF1KE0 NSCISKRCVS------LLLDLSQPLLP--SRLPKWSE-----GPCGSPG----SPGSNIE
. : ::.: : . : : .: .: :: .:: ::::
XP_011 QVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPC-APGRCENSPGS--F
360 370 380 390 400
180 190 200 210 220
pF1KE0 GFVCKFSFKGMCRPLALGGPGQVTYTTP-------FQTTSSSLEAVPFA-SAANVACGEG
:: .:.. : . . : .: .: : . : . .:: . .
XP_011 RCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQ
410 420 430 440 450 460
230 240 250 260 270 280
pF1KE0 DKDETQSHYFLCKEKA----PDVF----DWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGD
: :: . :: . : : : : : : : . : ..
XP_011 DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTA
470 480 490 500 510 520
290 300 310 320 330
pF1KE0 GSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDS
::: :.: ::: . : . . :. :: : : : . .: .. : ::.:.: ..
XP_011 GSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYG-RCE-NTEG-SFQCVCPMGFQPNT
530 540 550 560 570 580
340 350 360 370 380 390
pF1KE0 SQLDCVDVDECQDS-PC-AQECVNTPGGFRCE-CWVGYEPGGPGEGACQDVDECALGRSP
. .: :::::.. : .:::::.::.:.:. : :.. .: : :::::. : :
XP_011 AGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLH---RGRCTDVDECSSGAPP
590 600 610 620 630 640
400 410 420 430 440 450
pF1KE0 CA-QG-CTNTDGSFHCSCEEGY-VLAGEDGTQCQDVDECVGPGGPLC--DSLCFNTQGSF
:. .: ::::.:::.::: :: . .:. : : ::.::. : .: . :.::.:::
XP_011 CGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP-CADVNECLE--GDFCFPHGECLNTDGSF
650 660 670 680 690
460 470 480 490 500 510
pF1KE0 HCGCLPGWVLAPNGVSCTMGPVSLGPPSGPPDEEDKGEKEGSTVPRAATASPTRGPEGTL
: : ::. .: :.::
XP_011 ACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLD
700 710 720 730 740 750
>--
initn: 211 init1: 185 opt: 510 Z-score: 332.5 bits: 72.9 E(85289): 8.9e-12
Smith-Waterman score: 510; 37.0% identity (54.0% similar) in 289 aa overlap (271-541:727-987)
250 260 270 280 290 300
pF1KE0 KEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTC
:.. . :::: : : :: : ::..:
XP_011 SFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC
700 710 720 730 740 750
310 320 330 340 350
pF1KE0 ASRNPCSS-SP--CRGGATCVLGPHGKNYTC--RCPQGYQLDSSQLDCVDVDECQD-SP-
. . : .: : :. : .: .: : : ::. . . : ::::::. .:
XP_011 LDVDECRERGPALC-GSQRCENSPG--SYRCVRDCDPGYHA-GPEGTCDDVDECQEYGPE
760 770 780 790 800 810
360 370 380 390 400
pF1KE0 -C-AQECVNTPGGFRCE--CWVGYEPGGPGEGACQDVDECALGRSPCAQG--CTNTDGSF
: ::.: ::::..:: : ::.: :: :.::::::: .:: :. : : :::
XP_011 ICGAQRCENTPGSYRCTPACDPGYQPT-PG-GGCQDVDECR-NRSFCGAHAVCQNLPGSF
820 830 840 850 860
410 420 430 440 450 460
pF1KE0 HCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC
.: :..:: : .:: .: ::.:: : .:: :..::: : : ::.
XP_011 QCLCDQGYEGA-RDGRHCVDVNECETLQGVCGAALCENVEGSFLCVC-------PNS---
870 880 890 900 910
470 480 490 500 510 520
pF1KE0 TMGPVSLGPPSG---PPDEEDKGEKEGSTVPRAATAS--PTRGPEGTLKATPTTSRPSLS
: . : .: :: . . : :: :.: .. :.: : : :::
XP_011 ---PEEFDPMTGRCVPP-RTSAGTFPGSQ-PQAPASPVLPARPPP-----PPLPRRPSTP
920 930 940 950 960
530 540 550 560 570 580
pF1KE0 SDAPITSAPLKMLAPSGSPGVWREPSIHHATAASGPQEPAGGDSSVATQNNDGTDGQKLL
..:. :. . ...:
XP_011 RQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEY
970 980 990 1000 1010 1020
>>XP_011525688 (OMIM: 604710,613177) PREDICTED: latent-t (1436 aa)
initn: 260 init1: 260 opt: 549 Z-score: 356.8 bits: 77.4 E(85289): 3.9e-13
Smith-Waterman score: 566; 33.2% identity (51.1% similar) in 407 aa overlap (107-467:535-929)
80 90 100 110 120 130
pF1KE0 AQLLRREAALTARMSKFWIGLQREKGKCLDPSLPLKGF-SWVGG--GEDTPYSNWHKELR
: ::: .. .:.: :. : :. ..
XP_011 LPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNP
510 520 530 540 550 560
140 150 160 170
pF1KE0 NSCISKRCVS------LLLDLSQPLLP--SRLPKWSE-----GPCGSPG----SPGSNIE
. : ::.: : . : : .: .: :: .:: ::::
XP_011 QVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPC-APGRCENSPGS--F
570 580 590 600 610 620
180 190 200 210 220
pF1KE0 GFVCKFSFKGMCRPLALGGPGQVTYTTP-------FQTTSSSLEAVPFA-SAANVACGEG
:: .:.. : . . : .: .: : . : . .:: . .
XP_011 RCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQ
630 640 650 660 670 680
230 240 250 260 270 280
pF1KE0 DKDETQSHYFLCKEKA----PDVF----DWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGD
: :: . :: . : : : : : : : . : ..
XP_011 DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTA
690 700 710 720 730 740
290 300 310 320 330
pF1KE0 GSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDS
::: :.: ::: . : . . :. :: : : : . .: .. : ::.:.: ..
XP_011 GSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYG-RCE-NTEG-SFQCVCPMGFQPNT
750 760 770 780 790
340 350 360 370 380 390
pF1KE0 SQLDCVDVDECQDS-PC-AQECVNTPGGFRCE-CWVGYEPGGPGEGACQDVDECALGRSP
. .: :::::.. : .:::::.::.:.:. : :.. .: : :::::. : :
XP_011 AGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLH---RGRCTDVDECSSGAPP
800 810 820 830 840 850
400 410 420 430 440 450
pF1KE0 CA-QG-CTNTDGSFHCSCEEGY-VLAGEDGTQCQDVDECVGPGGPLC--DSLCFNTQGSF
:. .: ::::.:::.::: :: . .:. : : ::.::. : .: . :.::.:::
XP_011 CGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP-CADVNECLE--GDFCFPHGECLNTDGSF
860 870 880 890 900 910
460 470 480 490 500 510
pF1KE0 HCGCLPGWVLAPNGVSCTMGPVSLGPPSGPPDEEDKGEKEGSTVPRAATASPTRGPEGTL
: : ::. .: :.::
XP_011 ACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLD
920 930 940 950 960 970
>>XP_016882843 (OMIM: 604710,613177) PREDICTED: latent-t (1438 aa)
initn: 260 init1: 260 opt: 549 Z-score: 356.8 bits: 77.4 E(85289): 3.9e-13
Smith-Waterman score: 560; 31.9% identity (51.2% similar) in 385 aa overlap (107-467:535-887)
80 90 100 110 120 130
pF1KE0 AQLLRREAALTARMSKFWIGLQREKGKCLDPSLPLKGF-SWVGG--GEDTPYSNWHKELR
: ::: .. .:.: :. : :. ..
XP_016 LPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNP
510 520 530 540 550 560
140 150 160 170 180
pF1KE0 NSCISKRCVS------LLLDLSQPLLPSRLPKWSEGPCGSPGSPGSNIEGFVCKFSFKGM
. : ::.: : . : :. . : : : . :
XP_016 QVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECHRVPPP--------CDL---GR
570 580 590 600 610
190 200 210 220 230 240
pF1KE0 CRPLALGGPGQVTYTTP--FQTT--SSSLEAVPFASAANVACGEGD-KDETQSHYFLCKE
:. . ::. . : .:.. ..: . : . . ::.: :. : .:
XP_016 CE----NTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPA
620 630 640 650 660
250 260 270 280 290 300
pF1KE0 KAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCAS
: : : : . : .. ::: :.: ::: . : .
XP_016 --------GFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQD
670 680 690 700 710 720
310 320 330 340 350
pF1KE0 RNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDS-PC-AQEC
. :. :: : : : . .: .. : ::.:.: ... .: :::::.. : .:::
XP_016 VDECARSPPPCTYG-RCE-NTEG-SFQCVCPMGFQPNTAGSECEDVDECENHLACPGQEC
730 740 750 760 770
360 370 380 390 400 410
pF1KE0 VNTPGGFRCE-CWVGYEPGGPGEGACQDVDECALGRSPCA-QG-CTNTDGSFHCSCEEGY
::.::.:.:. : :.. .: : :::::. : ::. .: ::::.:::.::: ::
XP_016 VNSPGSFQCRTCPSGHHLH---RGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGY
780 790 800 810 820 830
420 430 440 450 460 470
pF1KE0 -VLAGEDGTQCQDVDECVGPGGPLC--DSLCFNTQGSFHCGCLPGWVLAPNGVSCTMGPV
. .:. : : ::.::. : .: . :.::.::: : : ::. .: :.::
XP_016 RAPSGRPGP-CADVNECLE--GDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDE
840 850 860 870 880 890
480 490 500 510 520 530
pF1KE0 SLGPPSGPPDEEDKGEKEGSTVPRAATASPTRGPEGTLKATPTTSRPSLSSDAPITSAPL
XP_016 CSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPG
900 910 920 930 940 950
>--
initn: 317 init1: 152 opt: 392 Z-score: 258.6 bits: 59.3 E(85289): 1.1e-07
Smith-Waterman score: 418; 37.5% identity (54.2% similar) in 216 aa overlap (271-467:899-1108)
250 260 270 280 290 300
pF1KE0 KEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTC
:.. . :::: : : :: : ::..:
XP_016 SFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC
870 880 890 900 910 920
310 320 330 340 350
pF1KE0 ASRNPCSS-SP--CRGGATCVLGPHGKNYTC--RCPQGYQLDSSQLDCVDVDECQD-SP-
. . : .: : :. : .: .: : : ::. . . : ::::::. .:
XP_016 LDVDECRERGPALC-GSQRCENSPG--SYRCVRDCDPGYHA-GPEGTCDDVDECQEYGPE
930 940 950 960 970 980
360 370 380 390 400
pF1KE0 -C-AQECVNTPGGFRCE--CWVGYEPGGPGEGACQDVDECALGRSPC-AQGCTNTDGSFH
: ::.: ::::..:: : ::.: :: :.::::.:: .. : : : :..:::
XP_016 ICGAQRCENTPGSYRCTPACDPGYQPT-PG-GGCQDVNECETLQGVCGAALCENVEGSFL
990 1000 1010 1020 1030 1040
410 420 430 440 450 460
pF1KE0 CSC----EEGYVLAGE--DGTQCQDVDECVGPGGPLCDS-LCFNTQGSFHCGCLPGWVLA
: : :: ..:. ::::: .: : .: :: .. : : :.
XP_016 CVCPNSPEEFDPMTGRCVPPRTSADVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYH
1050 1060 1070 1080 1090 1100
470 480 490 500 510 520
pF1KE0 PNGVSCTMGPVSLGPPSGPPDEEDKGEKEGSTVPRAATASPTRGPEGTLKATPTTSRPSL
. . :
XP_016 TQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNL
1110 1120 1130 1140 1150 1160
>>XP_011525687 (OMIM: 604710,613177) PREDICTED: latent-t (1478 aa)
initn: 260 init1: 260 opt: 549 Z-score: 356.6 bits: 77.4 E(85289): 4e-13
Smith-Waterman score: 566; 33.2% identity (51.1% similar) in 407 aa overlap (107-467:535-929)
80 90 100 110 120 130
pF1KE0 AQLLRREAALTARMSKFWIGLQREKGKCLDPSLPLKGF-SWVGG--GEDTPYSNWHKELR
: ::: .. .:.: :. : :. ..
XP_011 LPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNP
510 520 530 540 550 560
140 150 160 170
pF1KE0 NSCISKRCVS------LLLDLSQPLLP--SRLPKWSE-----GPCGSPG----SPGSNIE
. : ::.: : . : : .: .: :: .:: ::::
XP_011 QVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPC-APGRCENSPGS--F
570 580 590 600 610 620
180 190 200 210 220
pF1KE0 GFVCKFSFKGMCRPLALGGPGQVTYTTP-------FQTTSSSLEAVPFA-SAANVACGEG
:: .:.. : . . : .: .: : . : . .:: . .
XP_011 RCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQ
630 640 650 660 670 680
230 240 250 260 270 280
pF1KE0 DKDETQSHYFLCKEKA----PDVF----DWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGD
: :: . :: . : : : : : : : . : ..
XP_011 DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTA
690 700 710 720 730 740
290 300 310 320 330
pF1KE0 GSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDS
::: :.: ::: . : . . :. :: : : : . .: .. : ::.:.: ..
XP_011 GSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYG-RCE-NTEG-SFQCVCPMGFQPNT
750 760 770 780 790
340 350 360 370 380 390
pF1KE0 SQLDCVDVDECQDS-PC-AQECVNTPGGFRCE-CWVGYEPGGPGEGACQDVDECALGRSP
. .: :::::.. : .:::::.::.:.:. : :.. .: : :::::. : :
XP_011 AGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLH---RGRCTDVDECSSGAPP
800 810 820 830 840 850
400 410 420 430 440 450
pF1KE0 CA-QG-CTNTDGSFHCSCEEGY-VLAGEDGTQCQDVDECVGPGGPLC--DSLCFNTQGSF
:. .: ::::.:::.::: :: . .:. : : ::.::. : .: . :.::.:::
XP_011 CGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP-CADVNECLE--GDFCFPHGECLNTDGSF
860 870 880 890 900 910
460 470 480 490 500 510
pF1KE0 HCGCLPGWVLAPNGVSCTMGPVSLGPPSGPPDEEDKGEKEGSTVPRAATASPTRGPEGTL
: : ::. .: :.::
XP_011 ACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLD
920 930 940 950 960 970
>--
initn: 245 init1: 150 opt: 403 Z-score: 265.4 bits: 60.6 E(85289): 4.8e-08
Smith-Waterman score: 403; 40.7% identity (63.5% similar) in 167 aa overlap (296-454:931-1085)
270 280 290 300 310 320
pF1KE0 FNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKN
:. :. .. :.:. : : . : .
XP_011 PHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGIC----TNTDG----S
910 920 930 940 950
330 340 350 360 370
pF1KE0 YTCRCPQGYQLDSSQLDCVDVDECQD-SP--C-AQECVNTPGGFRC--ECWVGYEPGGPG
. : :: :.. . .:.:::::.. .: : .:.: :.::..:: .: ::. .::
XP_011 FECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYH-AGP-
960 970 980 990 1000 1010
380 390 400 410 420 430
pF1KE0 EGACQDVDECALGRSPCAQG--CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGP
::.:.::::: .:: :. : : :::.: :..:: : .:: .: ::.:: :
XP_011 EGTCDDVDECR-NRSFCGAHAVCQNLPGSFQCLCDQGYEGA-RDGRHCVDVNECETLQGV
1020 1030 1040 1050 1060
440 450 460 470 480 490
pF1KE0 LCDSLCFNTQGSFHCGCLPGWVLAPNGVSCTMGPVSLGPPSGPPDEEDKGEKEGSTVPRA
.:: :..::: : :
XP_011 CGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSADVDECQLFRDQVCKSGVCVNTA
1070 1080 1090 1100 1110 1120
>>XP_011525686 (OMIM: 604710,613177) PREDICTED: latent-t (1480 aa)
initn: 260 init1: 260 opt: 549 Z-score: 356.6 bits: 77.4 E(85289): 4e-13
Smith-Waterman score: 566; 33.2% identity (51.1% similar) in 407 aa overlap (107-467:535-929)
80 90 100 110 120 130
pF1KE0 AQLLRREAALTARMSKFWIGLQREKGKCLDPSLPLKGF-SWVGG--GEDTPYSNWHKELR
: ::: .. .:.: :. : :. ..
XP_011 LPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNP
510 520 530 540 550 560
140 150 160 170
pF1KE0 NSCISKRCVS------LLLDLSQPLLP--SRLPKWSE-----GPCGSPG----SPGSNIE
. : ::.: : . : : .: .: :: .:: ::::
XP_011 QVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPC-APGRCENSPGS--F
570 580 590 600 610 620
180 190 200 210 220
pF1KE0 GFVCKFSFKGMCRPLALGGPGQVTYTTP-------FQTTSSSLEAVPFA-SAANVACGEG
:: .:.. : . . : .: .: : . : . .:: . .
XP_011 RCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQ
630 640 650 660 670 680
230 240 250 260 270 280
pF1KE0 DKDETQSHYFLCKEKA----PDVF----DWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGD
: :: . :: . : : : : : : : . : ..
XP_011 DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTA
690 700 710 720 730 740
290 300 310 320 330
pF1KE0 GSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDS
::: :.: ::: . : . . :. :: : : : . .: .. : ::.:.: ..
XP_011 GSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYG-RCE-NTEG-SFQCVCPMGFQPNT
750 760 770 780 790
340 350 360 370 380 390
pF1KE0 SQLDCVDVDECQDS-PC-AQECVNTPGGFRCE-CWVGYEPGGPGEGACQDVDECALGRSP
. .: :::::.. : .:::::.::.:.:. : :.. .: : :::::. : :
XP_011 AGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLH---RGRCTDVDECSSGAPP
800 810 820 830 840 850
400 410 420 430 440 450
pF1KE0 CA-QG-CTNTDGSFHCSCEEGY-VLAGEDGTQCQDVDECVGPGGPLC--DSLCFNTQGSF
:. .: ::::.:::.::: :: . .:. : : ::.::. : .: . :.::.:::
XP_011 CGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP-CADVNECLE--GDFCFPHGECLNTDGSF
860 870 880 890 900 910
460 470 480 490 500 510
pF1KE0 HCGCLPGWVLAPNGVSCTMGPVSLGPPSGPPDEEDKGEKEGSTVPRAATASPTRGPEGTL
: : ::. .: :.::
XP_011 ACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLD
920 930 940 950 960 970
>--
initn: 317 init1: 152 opt: 392 Z-score: 258.5 bits: 59.3 E(85289): 1.2e-07
Smith-Waterman score: 418; 37.5% identity (54.2% similar) in 216 aa overlap (271-467:941-1150)
250 260 270 280 290 300
pF1KE0 KEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTC
:.. . :::: : : :: : ::..:
XP_011 SFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC
920 930 940 950 960 970
310 320 330 340 350
pF1KE0 ASRNPCSS-SP--CRGGATCVLGPHGKNYTC--RCPQGYQLDSSQLDCVDVDECQD-SP-
. . : .: : :. : .: .: : : ::. . . : ::::::. .:
XP_011 LDVDECRERGPALC-GSQRCENSPG--SYRCVRDCDPGYHA-GPEGTCDDVDECQEYGPE
980 990 1000 1010 1020
360 370 380 390 400
pF1KE0 -C-AQECVNTPGGFRCE--CWVGYEPGGPGEGACQDVDECALGRSPC-AQGCTNTDGSFH
: ::.: ::::..:: : ::.: :: :.::::.:: .. : : : :..:::
XP_011 ICGAQRCENTPGSYRCTPACDPGYQPT-PG-GGCQDVNECETLQGVCGAALCENVEGSFL
1030 1040 1050 1060 1070 1080
410 420 430 440 450 460
pF1KE0 CSC----EEGYVLAGE--DGTQCQDVDECVGPGGPLCDS-LCFNTQGSFHCGCLPGWVLA
: : :: ..:. ::::: .: : .: :: .. : : :.
XP_011 CVCPNSPEEFDPMTGRCVPPRTSADVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYH
1090 1100 1110 1120 1130 1140
470 480 490 500 510 520
pF1KE0 PNGVSCTMGPVSLGPPSGPPDEEDKGEKEGSTVPRAATASPTRGPEGTLKATPTTSRPSL
. . :
XP_011 TQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNL
1150 1160 1170 1180 1190 1200
>>XP_011525685 (OMIM: 604710,613177) PREDICTED: latent-t (1522 aa)
initn: 260 init1: 260 opt: 549 Z-score: 356.5 bits: 77.5 E(85289): 4.1e-13
Smith-Waterman score: 566; 33.2% identity (51.1% similar) in 407 aa overlap (107-467:535-929)
80 90 100 110 120 130
pF1KE0 AQLLRREAALTARMSKFWIGLQREKGKCLDPSLPLKGF-SWVGG--GEDTPYSNWHKELR
: ::: .. .:.: :. : :. ..
XP_011 LPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNP
510 520 530 540 550 560
140 150 160 170
pF1KE0 NSCISKRCVS------LLLDLSQPLLP--SRLPKWSE-----GPCGSPG----SPGSNIE
. : ::.: : . : : .: .: :: .:: ::::
XP_011 QVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPC-APGRCENSPGS--F
570 580 590 600 610 620
180 190 200 210 220
pF1KE0 GFVCKFSFKGMCRPLALGGPGQVTYTTP-------FQTTSSSLEAVPFA-SAANVACGEG
:: .:.. : . . : .: .: : . : . .:: . .
XP_011 RCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQ
630 640 650 660 670 680
230 240 250 260 270 280
pF1KE0 DKDETQSHYFLCKEKA----PDVF----DWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGD
: :: . :: . : : : : : : : . : ..
XP_011 DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTA
690 700 710 720 730 740
290 300 310 320 330
pF1KE0 GSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDS
::: :.: ::: . : . . :. :: : : : . .: .. : ::.:.: ..
XP_011 GSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYG-RCE-NTEG-SFQCVCPMGFQPNT
750 760 770 780 790
340 350 360 370 380 390
pF1KE0 SQLDCVDVDECQDS-PC-AQECVNTPGGFRCE-CWVGYEPGGPGEGACQDVDECALGRSP
. .: :::::.. : .:::::.::.:.:. : :.. .: : :::::. : :
XP_011 AGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLH---RGRCTDVDECSSGAPP
800 810 820 830 840 850
400 410 420 430 440 450
pF1KE0 CA-QG-CTNTDGSFHCSCEEGY-VLAGEDGTQCQDVDECVGPGGPLC--DSLCFNTQGSF
:. .: ::::.:::.::: :: . .:. : : ::.::. : .: . :.::.:::
XP_011 CGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP-CADVNECLE--GDFCFPHGECLNTDGSF
860 870 880 890 900 910
460 470 480 490 500 510
pF1KE0 HCGCLPGWVLAPNGVSCTMGPVSLGPPSGPPDEEDKGEKEGSTVPRAATASPTRGPEGTL
: : ::. .: :.::
XP_011 ACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLD
920 930 940 950 960 970
>--
initn: 482 init1: 185 opt: 476 Z-score: 310.8 bits: 69.0 E(85289): 1.4e-10
Smith-Waterman score: 476; 43.1% identity (59.4% similar) in 197 aa overlap (271-454:941-1129)
250 260 270 280 290 300
pF1KE0 KEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTC
:.. . :::: : : :: : ::..:
XP_011 SFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC
920 930 940 950 960 970
310 320 330 340 350
pF1KE0 ASRNPCSS-SP--CRGGATCVLGPHGKNYTC--RCPQGYQLDSSQLDCVDVDECQD-SP-
. . : .: : :. : .: .: : : ::. . . : ::::::. .:
XP_011 LDVDECRERGPALC-GSQRCENSPG--SYRCVRDCDPGYHA-GPEGTCDDVDECQEYGPE
980 990 1000 1010 1020
360 370 380 390 400
pF1KE0 -C-AQECVNTPGGFRCE--CWVGYEPGGPGEGACQDVDECALGRSPCAQG--CTNTDGSF
: ::.: ::::..:: : ::.: :: :.::::::: .:: :. : : :::
XP_011 ICGAQRCENTPGSYRCTPACDPGYQPT-PG-GGCQDVDECR-NRSFCGAHAVCQNLPGSF
1030 1040 1050 1060 1070 1080
410 420 430 440 450 460
pF1KE0 HCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC
.: :..:: : .:: .: ::.:: : .:: :..::: : :
XP_011 QCLCDQGYEGA-RDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGR
1090 1100 1110 1120 1130 1140
470 480 490 500 510 520
pF1KE0 TMGPVSLGPPSGPPDEEDKGEKEGSTVPRAATASPTRGPEGTLKATPTTSRPSLSSDAPI
XP_011 CVPPRTSADVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEE
1150 1160 1170 1180 1190 1200
>>XP_016882842 (OMIM: 604710,613177) PREDICTED: latent-t (1549 aa)
initn: 260 init1: 260 opt: 549 Z-score: 356.4 bits: 77.5 E(85289): 4.1e-13
Smith-Waterman score: 566; 33.2% identity (51.1% similar) in 407 aa overlap (107-467:535-929)
80 90 100 110 120 130
pF1KE0 AQLLRREAALTARMSKFWIGLQREKGKCLDPSLPLKGF-SWVGG--GEDTPYSNWHKELR
: ::: .. .:.: :. : :. ..
XP_016 LPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNP
510 520 530 540 550 560
140 150 160 170
pF1KE0 NSCISKRCVS------LLLDLSQPLLP--SRLPKWSE-----GPCGSPG----SPGSNIE
. : ::.: : . : : .: .: :: .:: ::::
XP_016 QVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPC-APGRCENSPGS--F
570 580 590 600 610 620
180 190 200 210 220
pF1KE0 GFVCKFSFKGMCRPLALGGPGQVTYTTP-------FQTTSSSLEAVPFA-SAANVACGEG
:: .:.. : . . : .: .: : . : . .:: . .
XP_016 RCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQ
630 640 650 660 670 680
230 240 250 260 270 280
pF1KE0 DKDETQSHYFLCKEKA----PDVF----DWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGD
: :: . :: . : : : : : : : . : ..
XP_016 DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTA
690 700 710 720 730 740
290 300 310 320 330
pF1KE0 GSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDS
::: :.: ::: . : . . :. :: : : : . .: .. : ::.:.: ..
XP_016 GSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYG-RCE-NTEG-SFQCVCPMGFQPNT
750 760 770 780 790
340 350 360 370 380 390
pF1KE0 SQLDCVDVDECQDS-PC-AQECVNTPGGFRCE-CWVGYEPGGPGEGACQDVDECALGRSP
. .: :::::.. : .:::::.::.:.:. : :.. .: : :::::. : :
XP_016 AGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLH---RGRCTDVDECSSGAPP
800 810 820 830 840 850
400 410 420 430 440 450
pF1KE0 CA-QG-CTNTDGSFHCSCEEGY-VLAGEDGTQCQDVDECVGPGGPLC--DSLCFNTQGSF
:. .: ::::.:::.::: :: . .:. : : ::.::. : .: . :.::.:::
XP_016 CGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP-CADVNECLE--GDFCFPHGECLNTDGSF
860 870 880 890 900 910
460 470 480 490 500 510
pF1KE0 HCGCLPGWVLAPNGVSCTMGPVSLGPPSGPPDEEDKGEKEGSTVPRAATASPTRGPEGTL
: : ::. .: :.::
XP_016 ACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLD
920 930 940 950 960 970
>>NP_001036010 (OMIM: 604710,613177) latent-transforming (1557 aa)
initn: 260 init1: 260 opt: 549 Z-score: 356.3 bits: 77.5 E(85289): 4.1e-13
Smith-Waterman score: 566; 33.2% identity (51.1% similar) in 407 aa overlap (107-467:457-851)
80 90 100 110 120 130
pF1KE0 AQLLRREAALTARMSKFWIGLQREKGKCLDPSLPLKGF-SWVGG--GEDTPYSNWHKELR
: ::: .. .:.: :. : :. ..
NP_001 LPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNP
430 440 450 460 470 480
140 150 160 170
pF1KE0 NSCISKRCVS------LLLDLSQPLLP--SRLPKWSE-----GPCGSPG----SPGSNIE
. : ::.: : . : : .: .: :: .:: ::::
NP_001 QVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPC-APGRCENSPGS--F
490 500 510 520 530 540
180 190 200 210 220
pF1KE0 GFVCKFSFKGMCRPLALGGPGQVTYTTP-------FQTTSSSLEAVPFA-SAANVACGEG
:: .:.. : . . : .: .: : . : . .:: . .
NP_001 RCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQ
550 560 570 580 590 600
230 240 250 260 270 280
pF1KE0 DKDETQSHYFLCKEKA----PDVF----DWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGD
: :: . :: . : : : : : : : . : ..
NP_001 DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTA
610 620 630 640 650 660
290 300 310 320 330
pF1KE0 GSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDS
::: :.: ::: . : . . :. :: : : : . .: .. : ::.:.: ..
NP_001 GSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYG-RCE-NTEG-SFQCVCPMGFQPNT
670 680 690 700 710 720
340 350 360 370 380 390
pF1KE0 SQLDCVDVDECQDS-PC-AQECVNTPGGFRCE-CWVGYEPGGPGEGACQDVDECALGRSP
. .: :::::.. : .:::::.::.:.:. : :.. .: : :::::. : :
NP_001 AGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLH---RGRCTDVDECSSGAPP
730 740 750 760 770
400 410 420 430 440 450
pF1KE0 CA-QG-CTNTDGSFHCSCEEGY-VLAGEDGTQCQDVDECVGPGGPLC--DSLCFNTQGSF
:. .: ::::.:::.::: :: . .:. : : ::.::. : .: . :.::.:::
NP_001 CGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP-CADVNECLE--GDFCFPHGECLNTDGSF
780 790 800 810 820 830
460 470 480 490 500 510
pF1KE0 HCGCLPGWVLAPNGVSCTMGPVSLGPPSGPPDEEDKGEKEGSTVPRAATASPTRGPEGTL
: : ::. .: :.::
NP_001 ACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLD
840 850 860 870 880 890
>--
initn: 211 init1: 185 opt: 510 Z-score: 332.0 bits: 73.0 E(85289): 9.4e-12
Smith-Waterman score: 510; 37.0% identity (54.0% similar) in 289 aa overlap (271-541:863-1123)
250 260 270 280 290 300
pF1KE0 KEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTC
:.. . :::: : : :: : ::..:
NP_001 SFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC
840 850 860 870 880 890
310 320 330 340 350
pF1KE0 ASRNPCSS-SP--CRGGATCVLGPHGKNYTC--RCPQGYQLDSSQLDCVDVDECQD-SP-
. . : .: : :. : .: .: : : ::. . . : ::::::. .:
NP_001 LDVDECRERGPALC-GSQRCENSPG--SYRCVRDCDPGYHA-GPEGTCDDVDECQEYGPE
900 910 920 930 940
360 370 380 390 400
pF1KE0 -C-AQECVNTPGGFRCE--CWVGYEPGGPGEGACQDVDECALGRSPCAQG--CTNTDGSF
: ::.: ::::..:: : ::.: :: :.::::::: .:: :. : : :::
NP_001 ICGAQRCENTPGSYRCTPACDPGYQPT-PG-GGCQDVDECR-NRSFCGAHAVCQNLPGSF
950 960 970 980 990 1000
410 420 430 440 450 460
pF1KE0 HCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC
.: :..:: : .:: .: ::.:: : .:: :..::: : : ::.
NP_001 QCLCDQGYEGA-RDGRHCVDVNECETLQGVCGAALCENVEGSFLCVC-------PNS---
1010 1020 1030 1040 1050
470 480 490 500 510 520
pF1KE0 TMGPVSLGPPSG---PPDEEDKGEKEGSTVPRAATAS--PTRGPEGTLKATPTTSRPSLS
: . : .: :: . . : :: :.: .. :.: : : :::
NP_001 ---PEEFDPMTGRCVPP-RTSAGTFPGSQ-PQAPASPVLPARPPP-----PPLPRRPSTP
1060 1070 1080 1090 1100
530 540 550 560 570 580
pF1KE0 SDAPITSAPLKMLAPSGSPGVWREPSIHHATAASGPQEPAGGDSSVATQNNDGTDGQKLL
..:. :. . ...:
NP_001 RQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEY
1110 1120 1130 1140 1150 1160
652 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 16:28:33 2016 done: Thu Nov 3 16:28:35 2016
Total Scan time: 13.680 Total Display time: 0.180
Function used was FASTA [36.3.4 Apr, 2011]