Result of FASTA (omim) for
pF1KE0278
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0278, 211 aa
1>>>pF1KE0278 211 - 211 aa - 211 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8272+/-0.000262; mu= 12.6898+/- 0.017
mean_var=91.5968+/-17.988, 0's: 0 Z-trim(122.3): 27 B-trim: 471 in 1/56
Lambda= 0.134009
statistics sampled from 40205 (40232) to 40205 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.804), E-opt: 0.2 (0.472), width: 16
Scan time: 6.420
The best scores are: opt bits E(85289)
XP_011540258 (OMIM: 616793) PREDICTED: group IIF s ( 211) 1544 307.4 1.1e-83
NP_073730 (OMIM: 616793) group IIF secretory phosp ( 211) 1544 307.4 1.1e-83
XP_011540257 (OMIM: 616793) PREDICTED: group IIF s ( 219) 1021 206.3 3.2e-53
NP_036532 (OMIM: 605630) group IID secretory phosp ( 145) 475 100.6 1.4e-21
NP_001155199 (OMIM: 172411) phospholipase A2, memb ( 144) 414 88.8 4.8e-18
NP_001155201 (OMIM: 172411) phospholipase A2, memb ( 144) 414 88.8 4.8e-18
NP_001155200 (OMIM: 172411) phospholipase A2, memb ( 144) 414 88.8 4.8e-18
NP_000291 (OMIM: 172411) phospholipase A2, membran ( 144) 414 88.8 4.8e-18
XP_005245950 (OMIM: 228980,601192) PREDICTED: calc ( 138) 382 82.6 3.4e-16
XP_011539890 (OMIM: 228980,601192) PREDICTED: calc ( 138) 382 82.6 3.4e-16
NP_000920 (OMIM: 228980,601192) calcium-dependent ( 138) 382 82.6 3.4e-16
XP_011539892 (OMIM: 228980,601192) PREDICTED: calc ( 138) 382 82.6 3.4e-16
XP_011539891 (OMIM: 228980,601192) PREDICTED: calc ( 138) 382 82.6 3.4e-16
XP_011539889 (OMIM: 228980,601192) PREDICTED: calc ( 138) 382 82.6 3.4e-16
XP_011539893 (OMIM: 228980,601192) PREDICTED: calc ( 138) 382 82.6 3.4e-16
XP_011539894 (OMIM: 228980,601192) PREDICTED: calc ( 138) 382 82.6 3.4e-16
XP_005245949 (OMIM: 228980,601192) PREDICTED: calc ( 169) 382 82.7 4e-16
XP_005245948 (OMIM: 228980,601192) PREDICTED: calc ( 169) 382 82.7 4e-16
XP_011539888 (OMIM: 228980,601192) PREDICTED: calc ( 169) 382 82.7 4e-16
NP_003552 (OMIM: 603603) group 10 secretory phosph ( 165) 375 81.3 1e-15
NP_000919 (OMIM: 172410) phospholipase A2 precurso ( 148) 304 67.5 1.2e-11
XP_011521000 (OMIM: 603603) PREDICTED: group 10 se ( 120) 288 64.4 9e-11
XP_011520999 (OMIM: 603603) PREDICTED: group 10 se ( 124) 288 64.4 9.2e-11
XP_011520998 (OMIM: 603603) PREDICTED: group 10 se ( 131) 288 64.4 9.6e-11
XP_011520997 (OMIM: 603603) PREDICTED: group 10 se ( 133) 288 64.4 9.8e-11
NP_001073868 (OMIM: 601658) otoconin-90 precursor ( 477) 261 59.6 9.9e-09
NP_001258743 (OMIM: 605630) group IID secretory ph ( 62) 205 48.1 3.6e-06
>>XP_011540258 (OMIM: 616793) PREDICTED: group IIF secre (211 aa)
initn: 1544 init1: 1544 opt: 1544 Z-score: 1623.3 bits: 307.4 E(85289): 1.1e-83
Smith-Waterman score: 1544; 100.0% identity (100.0% similar) in 211 aa overlap (1-211:1-211)
10 20 30 40 50 60
pF1KE0 MADGAKANPKGFKKKVLDRCFSGWRGPRFGASCPSRTSRSSLGMKKFFTVAILAGSVLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MADGAKANPKGFKKKVLDRCFSGWRGPRFGASCPSRTSRSSLGMKKFFTVAILAGSVLST
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AHGSLLNLKAMVEAVTGRSAILSFVGYGCYCGLGGRGQPKDEVDWCCHAHDCCYQELFDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHGSLLNLKAMVEAVTGRSAILSFVGYGCYCGLGGRGQPKDEVDWCCHAHDCCYQELFDQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 GCHPYVDHYDHTIENNTEIVCSDLNKTECDKQTCMCDKNMVLCLMNQTYREEYRGFLNVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCHPYVDHYDHTIENNTEIVCSDLNKTECDKQTCMCDKNMVLCLMNQTYREEYRGFLNVY
130 140 150 160 170 180
190 200 210
pF1KE0 CQGPTPNCSIYEPPPEEVTCSHQSPAPPAPP
:::::::::::::::::::::::::::::::
XP_011 CQGPTPNCSIYEPPPEEVTCSHQSPAPPAPP
190 200 210
>>NP_073730 (OMIM: 616793) group IIF secretory phospholi (211 aa)
initn: 1544 init1: 1544 opt: 1544 Z-score: 1623.3 bits: 307.4 E(85289): 1.1e-83
Smith-Waterman score: 1544; 100.0% identity (100.0% similar) in 211 aa overlap (1-211:1-211)
10 20 30 40 50 60
pF1KE0 MADGAKANPKGFKKKVLDRCFSGWRGPRFGASCPSRTSRSSLGMKKFFTVAILAGSVLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 MADGAKANPKGFKKKVLDRCFSGWRGPRFGASCPSRTSRSSLGMKKFFTVAILAGSVLST
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AHGSLLNLKAMVEAVTGRSAILSFVGYGCYCGLGGRGQPKDEVDWCCHAHDCCYQELFDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 AHGSLLNLKAMVEAVTGRSAILSFVGYGCYCGLGGRGQPKDEVDWCCHAHDCCYQELFDQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 GCHPYVDHYDHTIENNTEIVCSDLNKTECDKQTCMCDKNMVLCLMNQTYREEYRGFLNVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 GCHPYVDHYDHTIENNTEIVCSDLNKTECDKQTCMCDKNMVLCLMNQTYREEYRGFLNVY
130 140 150 160 170 180
190 200 210
pF1KE0 CQGPTPNCSIYEPPPEEVTCSHQSPAPPAPP
:::::::::::::::::::::::::::::::
NP_073 CQGPTPNCSIYEPPPEEVTCSHQSPAPPAPP
190 200 210
>>XP_011540257 (OMIM: 616793) PREDICTED: group IIF secre (219 aa)
initn: 1037 init1: 1021 opt: 1021 Z-score: 1076.6 bits: 206.3 E(85289): 3.2e-53
Smith-Waterman score: 1021; 100.0% identity (100.0% similar) in 142 aa overlap (1-142:1-142)
10 20 30 40 50 60
pF1KE0 MADGAKANPKGFKKKVLDRCFSGWRGPRFGASCPSRTSRSSLGMKKFFTVAILAGSVLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MADGAKANPKGFKKKVLDRCFSGWRGPRFGASCPSRTSRSSLGMKKFFTVAILAGSVLST
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AHGSLLNLKAMVEAVTGRSAILSFVGYGCYCGLGGRGQPKDEVDWCCHAHDCCYQELFDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHGSLLNLKAMVEAVTGRSAILSFVGYGCYCGLGGRGQPKDEVDWCCHAHDCCYQELFDQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 GCHPYVDHYDHTIENNTEIVCSDLNKTECDKQTCMCDKNMVLCLMNQTYREEYRGFLNVY
::::::::::::::::::::::
XP_011 GCHPYVDHYDHTIENNTEIVCSAPYLPPYLPEPQLRVSSLHGASPTCPKTTEATLRPDST
130 140 150 160 170 180
>>NP_036532 (OMIM: 605630) group IID secretory phospholi (145 aa)
initn: 452 init1: 367 opt: 475 Z-score: 508.6 bits: 100.6 E(85289): 1.4e-21
Smith-Waterman score: 475; 45.4% identity (74.5% similar) in 141 aa overlap (50-188:9-145)
20 30 40 50 60 70
pF1KE0 CFSGWRGPRFGASCPSRTSRSSLGMKKFFTVAILAGSVLSTAHGSLLNLKAMVEAVTGRS
....:: . .:..:::. ::. :::.
NP_036 MELALLCGLVVMAGVI--PIQGGILNLNKMVKQVTGKM
10 20 30
80 90 100 110 120 130
pF1KE0 AILSFVGYGCYCGLGGRGQPKDEVDWCCHAHDCCYQELFDQGCHPYVDHYDHTIENNTEI
:::. :::.::::::::::: .::::..:::::..: ::: : :.: ... .. .:
NP_036 PILSYWPYGCHCGLGGRGQPKDATDWCCQTHDCCYDHLKTQGCSIYKDYYRYNF-SQGNI
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE0 VCSDLNKTECDKQTCMCDKNMVLCLMNQ--TYREEYRGFLNVYCQGPTPNCSIYEPPPEE
::: . . :..: : :::....:: . ::... : . .:.: ::.:
NP_036 HCSD-KGSWCEQQLCACDKEVAFCLKRNLDTYQKRLRFYWRPHCRGQTPGC
100 110 120 130 140
200 210
pF1KE0 VTCSHQSPAPPAPP
>>NP_001155199 (OMIM: 172411) phospholipase A2, membrane (144 aa)
initn: 349 init1: 296 opt: 414 Z-score: 444.9 bits: 88.8 E(85289): 4.8e-18
Smith-Waterman score: 414; 38.8% identity (67.3% similar) in 147 aa overlap (44-188:1-144)
20 30 40 50 60 70
pF1KE0 KKVLDRCFSGWRGPRFGASCPSRTSRSSLGMKKFFTVAILAGSVLSTAHGSLLNLKAMVE
:: .. .:.. : :::.:.:.. :..
NP_001 MKTLLLLAVIMIFGLLQAHGNLVNFHRMIK
10 20 30
80 90 100 110 120 130
pF1KE0 AVTGRSAILSFVGYGCYCGLGGRGQPKDEVDWCCHAHDCCYQELFDQGCHPYVDHYDHTI
.::. : ::. :::.::.::::.::: .: :: .:::::..: .:: : .
NP_001 LTTGKEAALSYGFYGCHCGVGGRGSPKDATDRCCVTHDCCYKRLEKRGCGTKFLSYKFS-
40 50 60 70 80
140 150 160 170 180 190
pF1KE0 ENNTEIVCSDLNKTECDKQTCMCDKNMVLCLMNQ--TYREEYRGFLNVYCQGPTPNCSIY
.....:.:. .. : .: : ::: . :. . :: ..:. . : .:.: :: :
NP_001 NSGSRITCA--KQDSCRSQLCECDKAAATCFARNKTTYNKKYQYYSNKHCRGSTPRC
90 100 110 120 130 140
200 210
pF1KE0 EPPPEEVTCSHQSPAPPAPP
>>NP_001155201 (OMIM: 172411) phospholipase A2, membrane (144 aa)
initn: 349 init1: 296 opt: 414 Z-score: 444.9 bits: 88.8 E(85289): 4.8e-18
Smith-Waterman score: 414; 38.8% identity (67.3% similar) in 147 aa overlap (44-188:1-144)
20 30 40 50 60 70
pF1KE0 KKVLDRCFSGWRGPRFGASCPSRTSRSSLGMKKFFTVAILAGSVLSTAHGSLLNLKAMVE
:: .. .:.. : :::.:.:.. :..
NP_001 MKTLLLLAVIMIFGLLQAHGNLVNFHRMIK
10 20 30
80 90 100 110 120 130
pF1KE0 AVTGRSAILSFVGYGCYCGLGGRGQPKDEVDWCCHAHDCCYQELFDQGCHPYVDHYDHTI
.::. : ::. :::.::.::::.::: .: :: .:::::..: .:: : .
NP_001 LTTGKEAALSYGFYGCHCGVGGRGSPKDATDRCCVTHDCCYKRLEKRGCGTKFLSYKFS-
40 50 60 70 80
140 150 160 170 180 190
pF1KE0 ENNTEIVCSDLNKTECDKQTCMCDKNMVLCLMNQ--TYREEYRGFLNVYCQGPTPNCSIY
.....:.:. .. : .: : ::: . :. . :: ..:. . : .:.: :: :
NP_001 NSGSRITCA--KQDSCRSQLCECDKAAATCFARNKTTYNKKYQYYSNKHCRGSTPRC
90 100 110 120 130 140
200 210
pF1KE0 EPPPEEVTCSHQSPAPPAPP
>>NP_001155200 (OMIM: 172411) phospholipase A2, membrane (144 aa)
initn: 349 init1: 296 opt: 414 Z-score: 444.9 bits: 88.8 E(85289): 4.8e-18
Smith-Waterman score: 414; 38.8% identity (67.3% similar) in 147 aa overlap (44-188:1-144)
20 30 40 50 60 70
pF1KE0 KKVLDRCFSGWRGPRFGASCPSRTSRSSLGMKKFFTVAILAGSVLSTAHGSLLNLKAMVE
:: .. .:.. : :::.:.:.. :..
NP_001 MKTLLLLAVIMIFGLLQAHGNLVNFHRMIK
10 20 30
80 90 100 110 120 130
pF1KE0 AVTGRSAILSFVGYGCYCGLGGRGQPKDEVDWCCHAHDCCYQELFDQGCHPYVDHYDHTI
.::. : ::. :::.::.::::.::: .: :: .:::::..: .:: : .
NP_001 LTTGKEAALSYGFYGCHCGVGGRGSPKDATDRCCVTHDCCYKRLEKRGCGTKFLSYKFS-
40 50 60 70 80
140 150 160 170 180 190
pF1KE0 ENNTEIVCSDLNKTECDKQTCMCDKNMVLCLMNQ--TYREEYRGFLNVYCQGPTPNCSIY
.....:.:. .. : .: : ::: . :. . :: ..:. . : .:.: :: :
NP_001 NSGSRITCA--KQDSCRSQLCECDKAAATCFARNKTTYNKKYQYYSNKHCRGSTPRC
90 100 110 120 130 140
200 210
pF1KE0 EPPPEEVTCSHQSPAPPAPP
>>NP_000291 (OMIM: 172411) phospholipase A2, membrane as (144 aa)
initn: 349 init1: 296 opt: 414 Z-score: 444.9 bits: 88.8 E(85289): 4.8e-18
Smith-Waterman score: 414; 38.8% identity (67.3% similar) in 147 aa overlap (44-188:1-144)
20 30 40 50 60 70
pF1KE0 KKVLDRCFSGWRGPRFGASCPSRTSRSSLGMKKFFTVAILAGSVLSTAHGSLLNLKAMVE
:: .. .:.. : :::.:.:.. :..
NP_000 MKTLLLLAVIMIFGLLQAHGNLVNFHRMIK
10 20 30
80 90 100 110 120 130
pF1KE0 AVTGRSAILSFVGYGCYCGLGGRGQPKDEVDWCCHAHDCCYQELFDQGCHPYVDHYDHTI
.::. : ::. :::.::.::::.::: .: :: .:::::..: .:: : .
NP_000 LTTGKEAALSYGFYGCHCGVGGRGSPKDATDRCCVTHDCCYKRLEKRGCGTKFLSYKFS-
40 50 60 70 80
140 150 160 170 180 190
pF1KE0 ENNTEIVCSDLNKTECDKQTCMCDKNMVLCLMNQ--TYREEYRGFLNVYCQGPTPNCSIY
.....:.:. .. : .: : ::: . :. . :: ..:. . : .:.: :: :
NP_000 NSGSRITCA--KQDSCRSQLCECDKAAATCFARNKTTYNKKYQYYSNKHCRGSTPRC
90 100 110 120 130 140
200 210
pF1KE0 EPPPEEVTCSHQSPAPPAPP
>>XP_005245950 (OMIM: 228980,601192) PREDICTED: calcium- (138 aa)
initn: 352 init1: 305 opt: 382 Z-score: 411.7 bits: 82.6 E(85289): 3.4e-16
Smith-Waterman score: 382; 37.9% identity (66.4% similar) in 140 aa overlap (44-181:1-137)
20 30 40 50 60 70
pF1KE0 KKVLDRCFSGWRGPRFGASCPSRTSRSSLGMKKFFTVAILAGSVLSTAHGSLLNLKAMVE
:: .. .: . . . ...:.::.::.:.:
XP_005 MKGLLPLAWFLACSVPAVQGGLLDLKSMIE
10 20 30
80 90 100 110 120 130
pF1KE0 AVTGRSAILSFVGYGCYCGLGGRGQPKDEVDWCCHAHDCCYQELFDQGCHPYVDHYDHTI
:::..:. .. :::::: :::: ::: .:::: ::: :: .: ..::. .. : . .
XP_005 KVTGKNALTNYGFYGCYCGWGGRGTPKDGTDWCCWAHDHCYGRLEEKGCNIRTQSYKYRF
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE0 ENNTEIVCSDLNKTECDKQTCMCDKNMVLCLMN--QTYREEYRGFLNVYCQGPTPNCSIY
.. ..: : . : ::...: :: ..: .:. : :. :
XP_005 AWGV-VTCEP--GPFCHVNLCACDRKLVYCLKRNLRSYNPQYQYFPNILCS
100 110 120 130
200 210
pF1KE0 EPPPEEVTCSHQSPAPPAPP
>>XP_011539890 (OMIM: 228980,601192) PREDICTED: calcium- (138 aa)
initn: 352 init1: 305 opt: 382 Z-score: 411.7 bits: 82.6 E(85289): 3.4e-16
Smith-Waterman score: 382; 37.9% identity (66.4% similar) in 140 aa overlap (44-181:1-137)
20 30 40 50 60 70
pF1KE0 KKVLDRCFSGWRGPRFGASCPSRTSRSSLGMKKFFTVAILAGSVLSTAHGSLLNLKAMVE
:: .. .: . . . ...:.::.::.:.:
XP_011 MKGLLPLAWFLACSVPAVQGGLLDLKSMIE
10 20 30
80 90 100 110 120 130
pF1KE0 AVTGRSAILSFVGYGCYCGLGGRGQPKDEVDWCCHAHDCCYQELFDQGCHPYVDHYDHTI
:::..:. .. :::::: :::: ::: .:::: ::: :: .: ..::. .. : . .
XP_011 KVTGKNALTNYGFYGCYCGWGGRGTPKDGTDWCCWAHDHCYGRLEEKGCNIRTQSYKYRF
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE0 ENNTEIVCSDLNKTECDKQTCMCDKNMVLCLMN--QTYREEYRGFLNVYCQGPTPNCSIY
.. ..: : . : ::...: :: ..: .:. : :. :
XP_011 AWGV-VTCEP--GPFCHVNLCACDRKLVYCLKRNLRSYNPQYQYFPNILCS
100 110 120 130
200 210
pF1KE0 EPPPEEVTCSHQSPAPPAPP
211 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 17:55:37 2016 done: Thu Nov 3 17:55:38 2016
Total Scan time: 6.420 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]