Result of FASTA (ccds) for
pF1KE0253
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0253, 392 aa
1>>>pF1KE0253 392 - 392 aa - 392 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5743+/-0.000936; mu= 14.8632+/- 0.056
mean_var=59.8218+/-11.941, 0's: 0 Z-trim(104.8): 16 B-trim: 6 in 1/49
Lambda= 0.165823
statistics sampled from 8101 (8107) to 8101 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.618), E-opt: 0.2 (0.249), width: 16
Scan time: 2.470
The best scores are: opt bits E(32554)
CCDS8447.1 PANX3 gene_id:116337|Hs108|chr11 ( 392) 2578 625.3 2.9e-179
CCDS8296.1 PANX1 gene_id:24145|Hs108|chr11 ( 426) 929 230.8 1.8e-60
CCDS54544.1 PANX2 gene_id:56666|Hs108|chr22 ( 643) 528 134.9 2e-31
CCDS14085.2 PANX2 gene_id:56666|Hs108|chr22 ( 677) 528 134.9 2.1e-31
>>CCDS8447.1 PANX3 gene_id:116337|Hs108|chr11 (392 aa)
initn: 2578 init1: 2578 opt: 2578 Z-score: 3331.7 bits: 625.3 E(32554): 2.9e-179
Smith-Waterman score: 2578; 100.0% identity (100.0% similar) in 392 aa overlap (1-392:1-392)
10 20 30 40 50 60
pF1KE0 MSLAHTAAEYMLSDALLPDRRGPRLKGLRLELPLDRIVKFVAVGSPLLLMSLAFAQEFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS84 MSLAHTAAEYMLSDALLPDRRGPRLKGLRLELPLDRIVKFVAVGSPLLLMSLAFAQEFSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GSPISCFSPSNFSIRQAAYVDSSCWDSLLHHKQDGPGQDKMKSLWPHKALPYSLLALALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS84 GSPISCFSPSNFSIRQAAYVDSSCWDSLLHHKQDGPGQDKMKSLWPHKALPYSLLALALL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 MYLPVLLWQYAAVPALSSDLLFIISELDKSYNRSIRLVQHMLKIRQKSSDPYVFWNELEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS84 MYLPVLLWQYAAVPALSSDLLFIISELDKSYNRSIRLVQHMLKIRQKSSDPYVFWNELEK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ARKERYFEFPLLERYLACKQRSHSLVATYLLRNSLLLIFTSATYLYLGHFHLDVFFQEEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS84 ARKERYFEFPLLERYLACKQRSHSLVATYLLRNSLLLIFTSATYLYLGHFHLDVFFQEEF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 SCSIKTGLLSDETHVPNLITCRLTSLSIFQIVSLSSVAIYTILVPVIIYNLTRLCRWDKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS84 SCSIKTGLLSDETHVPNLITCRLTSLSIFQIVSLSSVAIYTILVPVIIYNLTRLCRWDKR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 LLSVYEMLPAFDLLSRKMLGCPINDLNVILLFLRANISELISFSWLSVLCVLKDTTTQKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS84 LLSVYEMLPAFDLLSRKMLGCPINDLNVILLFLRANISELISFSWLSVLCVLKDTTTQKH
310 320 330 340 350 360
370 380 390
pF1KE0 NIDTVVDFMTLLAGLEPSKPKHLTNSACDEHP
::::::::::::::::::::::::::::::::
CCDS84 NIDTVVDFMTLLAGLEPSKPKHLTNSACDEHP
370 380 390
>>CCDS8296.1 PANX1 gene_id:24145|Hs108|chr11 (426 aa)
initn: 927 init1: 353 opt: 929 Z-score: 1199.1 bits: 230.8 E(32554): 1.8e-60
Smith-Waterman score: 929; 43.3% identity (72.5% similar) in 360 aa overlap (1-355:1-357)
10 20 30 40 50 60
pF1KE0 MSLAHTAAEYMLSDALLPDRRGPRLKGLRLELPLDRIVKFVAVGSPLLLMSLAFAQEFSS
:..:. :.::..:: :: . :..::::::: .:..: .::: ::::.:::::::.:
CCDS82 MAIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GSPISCFSPSNFSIRQAAYVDSSCWDSLLHHKQDGPGQDKMKSLWPHKALPYSLLALALL
:. :::::::.:: ::::.::: :: .. ..:.. ... :: :: .:: :: .:.:
CCDS82 GTQISCFSPSSFSWRQAAFVDSYCWAAV-QQKNSLQSESGNLPLWLHKFFPYILLLFAIL
70 80 90 100 110
130 140 150 160 170
pF1KE0 MYLPVLLWQYAAVPALSSDLLFIISELDKSYNRSIRLVQHM--LKIRQKS-SDPYVFWNE
.::: :.:..::.: . ::: ::. :::: :::.:. .. : .:. . : : : :
CCDS82 LYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSARDLDMRDGACSVPGVTENL
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 LEKARK--ERYFEFPLLERYLACKQRSHSLVATYLLRNSLLLIFTSATYLYLGHFHLDVF
.. . : .:..:..:.:: :. :..:. :. : ::. . .:::..
CCDS82 GQSLWEVSESHFKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSS
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 FQEEFSCSIKTGLLSDETHVPNLITCRLTSLSIFQIVSLSSVAIYTILVPVIIYNLTRLC
...:: ::::.:.: ... ::. . :.: ...:::..:. ....:..:.::..:.:
CCDS82 LSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 RWDKRLLSVYEMLPAFDLLSRKMLGCPINDLNVILLFLRANISELISFSWLSVLCVLKDT
: .:.:::.::.::.: : : :::.. :::. ::::. :.. :.:: .:..
CCDS82 RQKTDVLKVYEILPTFDVLHFKSEG--YNDLSLYNLFLEENISEVKSYKCLKVLENIKSS
300 310 320 330 340 350
360 370 380 390
pF1KE0 TTQKHNIDTVVDFMTLLAGLEPSKPKHLTNSACDEHP
CCDS82 GQGIDPMLLLTNLGMIKMDVVDGKTPMSAEMREEQGNQTAELQGMNIDSETKANNGEKNA
360 370 380 390 400 410
>>CCDS54544.1 PANX2 gene_id:56666|Hs108|chr22 (643 aa)
initn: 370 init1: 119 opt: 528 Z-score: 677.7 bits: 134.9 E(32554): 2e-31
Smith-Waterman score: 528; 30.4% identity (60.0% similar) in 395 aa overlap (1-378:11-389)
10 20 30 40
pF1KE0 MSLAHTAAEYMLSDALLP----DRRGPR---LKGLRLELPLDRIVKFVAV
:. : :.: : . .:: :. : : :.::::.::.: . .:
CCDS54 MHHLLEQSADMATALLAGEK-LRELILPGAQDDKAGALAALLLQLKLELPFDRVVTIGTV
10 20 30 40 50
50 60 70 80 90 100
pF1KE0 GSPLLLMSLAFAQEFSSGSPISCFSPSNFSIRQAAYVDSSCWDSLLHHKQDGPGQDKMKS
:.::..:.:...:. :: :..: ::. :: :. . :: : .. :: : :
CCDS54 LVPILLVTLVFTKNFAE-EPIYCYTPHNFTRDQALYARGYCWTEL---RDALPGVDA--S
60 70 80 90 100 110
110 120 130 140 150
pF1KE0 LWP----HKALPYSLLALALLMYLPVLLWQYAAVPALSSDLLFIISELDKSYNRSIRLVQ
::: :: :::.:::.: .::.:.: :.. : :.:.: :...:.:. :.:. .
CCDS54 LWPSLFEHKFLPYALLAFAAIMYVPALGWEFLASTRLTSELNFLLQEIDNCYHRAAEGRA
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE0 HMLKIRQKSSDPYVFWNE----LEKARKERYFEFPLLERYLACKQRSHSLVATYLLRNSL
.. . .:. : . : .:.:.::. : :.:.:: . ::. :. :: :. :
CCDS54 PKIEKQIQSKGPGITEREKREIIENAEKEKSPEQNLFEKYLERRGRSNFLAKLYLARHVL
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE0 LLIFTSATYLYLGHFHLDVFFQEEFSCSIKTGLLSDETHVPNL-ITCRLTSLSIFQIVSL
.:..... :: .. . :.::.:.. .. . : . ..:.: :... .:..
CCDS54 ILLLSAVPISYLCTYYA-TQKQNEFTCALGASPDGAAGAGPAVRVSCKLPSVQLQRIIAG
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE0 SSVAIYTILVPVIIYNLTRLCRWDKRLLSVYEMLPAFDLLSRKMLG-CPINDLNVILLFL
.... .. .:. :: .: . : . ... : . .:.. . :.:.. .:
CCDS54 VDIVLLCVMNLIILVNLIHLFIFRKSNF-IFDKLHKVGIKTRRQWRRSQFCDINILAMFC
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE0 RANISELISFSWLSVLCVLKDTTTQKHNIDTVVDFMTLLAGLEPSKPKHLTNSACDEHP
: ... :.. :. . .: :.:: :::.: :
CCDS54 NENRDHIKSLNRLDFITNESDLM-----YDNVVR--QLLAALAQSNHDATPTVRDSGVQT
360 370 380 390 400
CCDS54 VDPSANPAEPDGAAEPPVVKRPRKKMKWIPTSNPLPQPFKEPLAIMRVENSKAEKPKPAR
410 420 430 440 450 460
>>CCDS14085.2 PANX2 gene_id:56666|Hs108|chr22 (677 aa)
initn: 370 init1: 119 opt: 528 Z-score: 677.3 bits: 134.9 E(32554): 2.1e-31
Smith-Waterman score: 528; 30.4% identity (60.0% similar) in 395 aa overlap (1-378:11-389)
10 20 30 40
pF1KE0 MSLAHTAAEYMLSDALLP----DRRGPR---LKGLRLELPLDRIVKFVAV
:. : :.: : . .:: :. : : :.::::.::.: . .:
CCDS14 MHHLLEQSADMATALLAGEK-LRELILPGAQDDKAGALAALLLQLKLELPFDRVVTIGTV
10 20 30 40 50
50 60 70 80 90 100
pF1KE0 GSPLLLMSLAFAQEFSSGSPISCFSPSNFSIRQAAYVDSSCWDSLLHHKQDGPGQDKMKS
:.::..:.:...:. :: :..: ::. :: :. . :: : .. :: : :
CCDS14 LVPILLVTLVFTKNFAE-EPIYCYTPHNFTRDQALYARGYCWTEL---RDALPGVDA--S
60 70 80 90 100 110
110 120 130 140 150
pF1KE0 LWP----HKALPYSLLALALLMYLPVLLWQYAAVPALSSDLLFIISELDKSYNRSIRLVQ
::: :: :::.:::.: .::.:.: :.. : :.:.: :...:.:. :.:. .
CCDS14 LWPSLFEHKFLPYALLAFAAIMYVPALGWEFLASTRLTSELNFLLQEIDNCYHRAAEGRA
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE0 HMLKIRQKSSDPYVFWNE----LEKARKERYFEFPLLERYLACKQRSHSLVATYLLRNSL
.. . .:. : . : .:.:.::. : :.:.:: . ::. :. :: :. :
CCDS14 PKIEKQIQSKGPGITEREKREIIENAEKEKSPEQNLFEKYLERRGRSNFLAKLYLARHVL
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE0 LLIFTSATYLYLGHFHLDVFFQEEFSCSIKTGLLSDETHVPNL-ITCRLTSLSIFQIVSL
.:..... :: .. . :.::.:.. .. . : . ..:.: :... .:..
CCDS14 ILLLSAVPISYLCTYYA-TQKQNEFTCALGASPDGAAGAGPAVRVSCKLPSVQLQRIIAG
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE0 SSVAIYTILVPVIIYNLTRLCRWDKRLLSVYEMLPAFDLLSRKMLG-CPINDLNVILLFL
.... .. .:. :: .: . : . ... : . .:.. . :.:.. .:
CCDS14 VDIVLLCVMNLIILVNLIHLFIFRKSNF-IFDKLHKVGIKTRRQWRRSQFCDINILAMFC
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE0 RANISELISFSWLSVLCVLKDTTTQKHNIDTVVDFMTLLAGLEPSKPKHLTNSACDEHP
: ... :.. :. . .: :.:: :::.: :
CCDS14 NENRDHIKSLNRLDFITNESDLM-----YDNVVR--QLLAALAQSNHDATPTVRDSGVQT
360 370 380 390 400
CCDS14 VDPSANPAEPDGAAEPPVVKRPRKKMKWIPTSNPLPQPFKEPLAIMRVENSKAEKPKPAR
410 420 430 440 450 460
392 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 18:57:05 2016 done: Thu Nov 3 18:57:05 2016
Total Scan time: 2.470 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]